Immunology Mcqs-III (Gate Helpline)

7/30/2019 Immunology Mcqs-III (Gate Helpline)

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IMMUNOLOGYMCQs-III


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TOPIC: IMMUNE SYSTEM

1. Who recorded the process variolation (inducing infected particles in body for small pox) for thefirst time in the world?

a) American and Russian c) Chinese and Turksb) Japanese and Korean d) Indians and Africans2. Who coined the name vaccination or vaccine?

a) Edward Jenner c) Max Theilerb) Robert Koch d) Louis Pasteur

3. Who discovered phagocytosis?a) Paul ehrlich c) Jules Bordetb) Elie Metchnikoff d) Emil von Behring

4. Which receptor molecule activates immune cells responses after physical barrier breacha) TCR c) Fc receptorsb) TLRs d) B cell receptors

5. Cell type Receptori. Antigen presenting cells CD8+

ii. B cells MHCiii. Helper T cells BCRiv. Cytotoxic T cells CD4+

a) iv, i, ii, iii c) i, ii, iii, ivb) ii, i,iii, iv d) iv,ii,I,iii

6. Arthus reaction belongs to which type of hypersensitivitya) Type I c) Type IIIb) Type II d) Type IV

7. T helper cells binds toa) Free antigen c) Antigen+ MHC Ib) Antigen+ MHC II d) APCs+Antigen

8. Which of the following cells are antigen non specific?a) Lymphocytes c) Mast cellsb) Stem cells d) accessory cells

9. Due to genetic defects, a person X has no antibody and person Y has no T cells. X person is morelikely to succumb to

a) Diphtheria c) malignant myelomab) influenza d) polio

10.similarly person Y is more likely to succumb toa) Diphtheria c) malignant myelomab) influenza d) polio

TOPIC: CELLS AND ORGANS OF IMMUNE SYSTEM


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1. from which part of embryo do the RBC and WBC develop or forma) yolk sac c) fetal spleenb) fetal liver d) bone marrow

2. Which cells provides HIM (hematopoietic inducing- microenvironment) for hematopoietic stemcell?

a) Muscle cells c) stromal cellsb) Bone marrow cells d) lymphoid cells

3. Mach the followingAPCs platelets

Monocyte natural killer cells

Megakaryocyte neutrophils

Granulocyte-Monocyte progenitor dendritic cells

Lymphoid progenitor macrophage

a) iv, ii, iii, i, v c) iii, v, iv, i, iib) iv, iii, ii, i, v d) iii, v, i, ii, iv

4. At what size will the lymphocytes is called lymphoblast?a) 12m c)6mb) 3m d)15m

5. Which type of receptor will the NK cells express during ADCC (antibody dependent cellcytotoxicity)?

a) CD3 c) CD21b) CD4 d) CD16

6. Which of the following generally do not apply to bone marrow?a) cellular proliferation

b) differentiation of lymphocytes

c) cellular interaction

d) antigen dependent response

7. Which of the following applies uniquely to secondary lymphoid organ?a) presence of precursor of B and T cellsb) circulation of lymphocyte

c) terminal differentiation

d) cellular proliferation


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8. Major function of lymphoid system isa) innate immunity

b) inflammation

c) phagocytosis

d) Acquired immunity

9. Removal of bursa of fabricus from a chicken results ina) A markedly decreased no of circulating T cells

b) anemia

c) A delayed rejection of skin graft

d) no serum level of Ab

10.The germinal centers found in the cortical region of lymph nodes and peripheral region ofspleenic lymphatic tissue

a) support development of immature B and T cellb) Removed damaged RBCs from circulation

c) act as a source of stem cell

d) provide a infrastructure that on antigenic stimulation contains population B cell and plasma

cell

11.which of the following statements are correct about NK cells ?a)) They proliferate in response to antigen

b) They kill target cells by phagocytosis and intracellular digestion

c) they are the subset of polymorphonuclear cells

d) they kill target cells in a extracellular fashion

12.Mature dentritic cells are capable of which of the followinga) Activation of native antigen specific T cells

b) Removal of RBCs

c) Production of bradykinnins

d) Extracellular killing of target cell.

Immunology Mcqs-III (Gate Helpline)

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