Immune Parameters Correlate with Protection Against Ebola Virus Infection in Rodents and Nonhuman...

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Immune Parameters Correlate with Protection Against Ebola Virus Infection in Rodents and Nonhuman Primates by Gary Wong, Jason S. Richardson, Stéphane Pillet, Ami Patel, Xiangguo Qiu, Judie Alimonti, Jeff Hogan, Yi Zhang, Ayato Takada, Heinz Feldmann, and Gary P. Kobinger Sci Transl Med Volume 4(158):158ra146-158ra146 October 31, 2012 Published by AAAS

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Fig. 2 Survival and weight loss after challenge, humoral immune response after vaccination in guinea pigs. Gary Wong et al., Sci Transl Med 2012;4:158ra146 Published by AAAS

Transcript of Immune Parameters Correlate with Protection Against Ebola Virus Infection in Rodents and Nonhuman...

Page 1: Immune Parameters Correlate with Protection Against Ebola Virus Infection in Rodents and Nonhuman Primates by Gary Wong, Jason S. Richardson, Stéphane.

Immune Parameters Correlate with Protection Against Ebola Virus Infection in Rodents and Nonhuman Primates

by Gary Wong, Jason S. Richardson, Stéphane Pillet, Ami Patel, Xiangguo Qiu, Judie Alimonti, Jeff Hogan, Yi Zhang, Ayato Takada, Heinz Feldmann, and Gary P.

Kobinger

Sci Transl MedVolume 4(158):158ra146-158ra146

October 31, 2012

Published by AAAS

Page 2: Immune Parameters Correlate with Protection Against Ebola Virus Infection in Rodents and Nonhuman Primates by Gary Wong, Jason S. Richardson, Stéphane.

Fig. 1 Survival and weight loss after challenge, and cellular and humoral immune response after vaccination in mice.

Gary Wong et al., Sci Transl Med 2012;4:158ra146

Published by AAAS

Page 3: Immune Parameters Correlate with Protection Against Ebola Virus Infection in Rodents and Nonhuman Primates by Gary Wong, Jason S. Richardson, Stéphane.

Fig. 2 Survival and weight loss after challenge, humoral immune response after vaccination in guinea pigs.

Gary Wong et al., Sci Transl Med 2012;4:158ra146

Published by AAAS

Page 4: Immune Parameters Correlate with Protection Against Ebola Virus Infection in Rodents and Nonhuman Primates by Gary Wong, Jason S. Richardson, Stéphane.

Fig. 3 Humoral immune response in cynomolgus macaques.

Gary Wong et al., Sci Transl Med 2012;4:158ra146

Published by AAAS

Page 5: Immune Parameters Correlate with Protection Against Ebola Virus Infection in Rodents and Nonhuman Primates by Gary Wong, Jason S. Richardson, Stéphane.

Fig. 4 Cell-mediated immune response in cynomolgus macaques.

Gary Wong et al., Sci Transl Med 2012;4:158ra146

Published by AAAS

Page 6: Immune Parameters Correlate with Protection Against Ebola Virus Infection in Rodents and Nonhuman Primates by Gary Wong, Jason S. Richardson, Stéphane.

Fig. 5 Cytokine and chemokine levels in cynomolgus macaques.

Gary Wong et al., Sci Transl Med 2012;4:158ra146

Published by AAAS