Human Intervention in Evolution
-
Upload
quon-blevins -
Category
Documents
-
view
17 -
download
0
description
Transcript of Human Intervention in Evolution
![Page 1: Human Intervention in Evolution](https://reader030.fdocuments.in/reader030/viewer/2022032414/568132b8550346895d9971bf/html5/thumbnails/1.jpg)
![Page 2: Human Intervention in Evolution](https://reader030.fdocuments.in/reader030/viewer/2022032414/568132b8550346895d9971bf/html5/thumbnails/2.jpg)
Selective BreedingSelective Breeding This is a form of artificial selectionThis is a form of artificial selection Involves choosing individuals from a Involves choosing individuals from a
population that have a certain trait population that have a certain trait and breeding those individualsand breeding those individuals
This is done across several This is done across several generationsgenerations
Eventually the trait is seen in all of the Eventually the trait is seen in all of the offspring and becomes more offspring and becomes more pronouncedpronounced
Used in farming, agriculture, and race Used in farming, agriculture, and race horseshorses
![Page 3: Human Intervention in Evolution](https://reader030.fdocuments.in/reader030/viewer/2022032414/568132b8550346895d9971bf/html5/thumbnails/3.jpg)
![Page 4: Human Intervention in Evolution](https://reader030.fdocuments.in/reader030/viewer/2022032414/568132b8550346895d9971bf/html5/thumbnails/4.jpg)
Reproductive Technology used in livestock
Artificial insemination (AI) – sperm from a selected animal is extracted and artificially introducing it into a female reproductive tract
Sex selection through sperm sorting – sperm are collected and analysed – separated into two groups – X and Y carrying sperm – uses a fluorescent dye
![Page 5: Human Intervention in Evolution](https://reader030.fdocuments.in/reader030/viewer/2022032414/568132b8550346895d9971bf/html5/thumbnails/5.jpg)
Reproductive Technology used in livestock
Multiple Ovulation Embryo Transfer (MOET) stimulate a female to produce
many eggs at once use AI to fertilise them within
the body after 6 days the uterus is flushed
to extract the embryos these are then inserted into
other females to begin gestation
![Page 6: Human Intervention in Evolution](https://reader030.fdocuments.in/reader030/viewer/2022032414/568132b8550346895d9971bf/html5/thumbnails/6.jpg)
CloningCloning
Cloning - creating genetically Cloning - creating genetically identical copies of an organismidentical copies of an organism
Two methods:Two methods: Splitting embryosSplitting embryos
Creating an embryo using IVF and using a Creating an embryo using IVF and using a fine needle to extract embryo cells that can fine needle to extract embryo cells that can divide and form new identical embryosdivide and form new identical embryos
Somatic Cell Nuclear Transfer (SCNT)Somatic Cell Nuclear Transfer (SCNT) Inserting the nucleus of a somatic cell into Inserting the nucleus of a somatic cell into
an ovum that has had its nucleus removedan ovum that has had its nucleus removed
![Page 7: Human Intervention in Evolution](https://reader030.fdocuments.in/reader030/viewer/2022032414/568132b8550346895d9971bf/html5/thumbnails/7.jpg)
Cloning
![Page 8: Human Intervention in Evolution](https://reader030.fdocuments.in/reader030/viewer/2022032414/568132b8550346895d9971bf/html5/thumbnails/8.jpg)
![Page 9: Human Intervention in Evolution](https://reader030.fdocuments.in/reader030/viewer/2022032414/568132b8550346895d9971bf/html5/thumbnails/9.jpg)
Gene TherapyGene Therapy
![Page 10: Human Intervention in Evolution](https://reader030.fdocuments.in/reader030/viewer/2022032414/568132b8550346895d9971bf/html5/thumbnails/10.jpg)
Gene Therapy
Still in development Attempts to introduce normal
copies of genes into the cells of an individual with a genetic disorder
Involves cloning the gene using a plasmid and then using a vector (carrier) to get it into the cells
Vectors include inactivated viruses and liposomes
![Page 11: Human Intervention in Evolution](https://reader030.fdocuments.in/reader030/viewer/2022032414/568132b8550346895d9971bf/html5/thumbnails/11.jpg)
Gene Therapy
![Page 12: Human Intervention in Evolution](https://reader030.fdocuments.in/reader030/viewer/2022032414/568132b8550346895d9971bf/html5/thumbnails/12.jpg)
Gene therapy for Haemophilia
![Page 13: Human Intervention in Evolution](https://reader030.fdocuments.in/reader030/viewer/2022032414/568132b8550346895d9971bf/html5/thumbnails/13.jpg)
Prenatal Gene Therapy
![Page 14: Human Intervention in Evolution](https://reader030.fdocuments.in/reader030/viewer/2022032414/568132b8550346895d9971bf/html5/thumbnails/14.jpg)
Stem CellsStem Cells
When sperm fertilises an ovum it forms a When sperm fertilises an ovum it forms a zygote. zygote.
The single cell grows and divides. Within The single cell grows and divides. Within 5 or 6 days there are up to 120 cells. 5 or 6 days there are up to 120 cells.
They form into a ball called the They form into a ball called the blastocyst. blastocyst.
Each cell is Each cell is pluripotentpluripotent, capable of , capable of developing into any cell type in the developing into any cell type in the human body such as heart, skin or hair.human body such as heart, skin or hair.
Blastocyst
![Page 15: Human Intervention in Evolution](https://reader030.fdocuments.in/reader030/viewer/2022032414/568132b8550346895d9971bf/html5/thumbnails/15.jpg)
Stem Cells
Can make every cell type in the
body.
They are ‘pluripoten
t’
![Page 16: Human Intervention in Evolution](https://reader030.fdocuments.in/reader030/viewer/2022032414/568132b8550346895d9971bf/html5/thumbnails/16.jpg)
A doctor takes a sample of skin cells from the patient and isolates their DNA. A donor egg cell, emptied of its own genetic contents, is injected with the DNA from the patient. The embryo is nurtured to grow and divide into a blastocyst. Some blastocyst cells are harvested and coaxed with growth factors to mature into insulin-producing cells. Millions of insulin-producing cells are injected back into the patient. The patient's diabetes is temporarily 'reversed', with no side effects.
Therapeutic Cloning – to produce stem cells
![Page 17: Human Intervention in Evolution](https://reader030.fdocuments.in/reader030/viewer/2022032414/568132b8550346895d9971bf/html5/thumbnails/17.jpg)
Genetic Genetic ScreeningScreening
Genetic screening Genetic screening can be performed for can be performed for a variety of reasons:a variety of reasons:
Test carrier status for Test carrier status for a particular disordera particular disorder
Test whether there is Test whether there is a predisposition to a predisposition to cancercancer
Pre-natal testing for Pre-natal testing for expectant parentsexpectant parents
![Page 18: Human Intervention in Evolution](https://reader030.fdocuments.in/reader030/viewer/2022032414/568132b8550346895d9971bf/html5/thumbnails/18.jpg)
Gel electrophoresis
DNA microarrays
Hybridisation
Pedigree analysis
![Page 19: Human Intervention in Evolution](https://reader030.fdocuments.in/reader030/viewer/2022032414/568132b8550346895d9971bf/html5/thumbnails/19.jpg)
Reproductive technologyReproductive technology Assist in overcoming infertilityAssist in overcoming infertility Variety of methods:Variety of methods:
In-vitro fertilisation (IVF)In-vitro fertilisation (IVF) – sperm and – sperm and ovum extracted and allowed to fuse ovum extracted and allowed to fuse outside of the body Embryo inserted outside of the body Embryo inserted into the uterus at the six cell stageinto the uterus at the six cell stage
Gamete Intra-fallopian Transfer Gamete Intra-fallopian Transfer (GIFT)(GIFT) – sperm and ovum extracted – sperm and ovum extracted and injected into the fallopian tube of and injected into the fallopian tube of the female so fertilisation happens in the female so fertilisation happens in the bodythe body
![Page 20: Human Intervention in Evolution](https://reader030.fdocuments.in/reader030/viewer/2022032414/568132b8550346895d9971bf/html5/thumbnails/20.jpg)
Reproductive technologyReproductive technology
Intracytoplasmic Sperm InjectionIntracytoplasmic Sperm Injection – – sperm and ovum extracted and the sperm and ovum extracted and the sperm is injected directly into the sperm is injected directly into the ovum. Embryo inserted into the ovum. Embryo inserted into the uterus at six cell stage.uterus at six cell stage.
Preventing pregnancy Preventing pregnancy (contraception) also falls under (contraception) also falls under the category of reproductive the category of reproductive technologytechnology
![Page 21: Human Intervention in Evolution](https://reader030.fdocuments.in/reader030/viewer/2022032414/568132b8550346895d9971bf/html5/thumbnails/21.jpg)
IVF
![Page 22: Human Intervention in Evolution](https://reader030.fdocuments.in/reader030/viewer/2022032414/568132b8550346895d9971bf/html5/thumbnails/22.jpg)
GIFT
![Page 23: Human Intervention in Evolution](https://reader030.fdocuments.in/reader030/viewer/2022032414/568132b8550346895d9971bf/html5/thumbnails/23.jpg)
Intracytoplasmic Sperm Injection
![Page 24: Human Intervention in Evolution](https://reader030.fdocuments.in/reader030/viewer/2022032414/568132b8550346895d9971bf/html5/thumbnails/24.jpg)
Questions to complete
All Quickcheck
Biochallenge Page 652
Chapter Review: 2, 3, 4, 5, 6, 7, 9bcd, 11, 12