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Date of Preparation: 8/25/2014 CURRICULUM VITAE

NAME: George T.-J. Huang, D.D.S., M.S.D., D.Sc.

TITLE: Professor Director for Stem Cells and Regenerative Therapies INSTITUTION: The University of Tennessee Health Science Center Memphis, TN 38163 Lab, Cancer Research Building 19 S. Manassas St. Lab Rm 225, office 222 Memphis, TN 38163 Phone: 901-448-1490 http://www.uthsc.edu/dentistry/Fac_Depts/research.php DEPARMANT: Department of Bioscience Research College of Dentistry 875 Union Avenue Memphis, TN 38163

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EDUCATION: 1992 June Doctor of Science (D.Sc.) in Oral Biology, Dept. of Oral Biology, Boston University 1989 June Master of Science in Dentistry (M.S.D.), Dept. of Endodontics, Boston University 1988 June Certificate in Endodontics, Dept. of Endodontics, Boston University 1983 June Doctor of Dental Surgery (D.D.S.), School of Dentistry, Taipei Medical College BOARD CERTIFICATION: 1997 Nov Diplomate, American Board of Endodontics UNIVERSITY APPOINTMENTS: 2012- Professor, Director of Stem Cells and Regenerative Therapies The University of Tennessee Health Science Center, College of Dentistry 2011-2012 Associate Professor, Department of Endodontics

Boston University Henry M. Goldman School of Dental Medicine 2009-2011 Associate Professor, Chair and Herbert Schilder Professor in Endodontics

Director, Postgraduate Program in Endodontics Boston University Henry M. Goldman School of Dental Medicine

2009-2009 Director (Head), Associate Professor, Columbia University, College of Dental Medicine, Division of Endodontics

2005-2008 Associate Professor, University of Maryland, College of Dental Surgery, Dental School, Division of Endodontics

1999-2004 Director, Postgraduate Program, Section of Endodontics University of California, Los Angeles

1999-2000 Acting Chair, Section of Endodontics University of California, Los Angeles

1996-2003 Research Director, Section of Endodontics University of California, Los Angeles

1995-2004 Assistant Professor, Section of Endodontics University of California, Los Angeles

1994-1995 Lecturer in Endodontics, Section of Endodontics University of California, Los Angeles

1993-1995 Postgraduate Research Immunologist, School of Medicine University of California, San Diego

1992-1993 Postdoctoral Fellow, School of Medicine University of California, San Diego

1990-1992 Clinical Instructor, Dept. of Endodontics (Part-time), Boston University TEACHING EXPERIENCE: CLINICAL & DIDACTIC TEACHING (U Maryland 2005-2008, Columbia U/Boston U 2009-2012) A. Courses chaired 1. Postgraduate a. Biological basis of endodontics (2007-2008)

d. Endodontic Research (2005-2012)

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B. Course Participated 1. Postgraduate

a. Classic and Current Endodontic Literature (2005-2012) b. Biological basis of endodontics (2005-2012) c. Resident case presentation (2006-2011)

d. Clinical endodontics (2005-2012) e. Fundamentals of Endodontics (05-08) f. DBMS 642 course review (07-08)

g. Endodontic Oral Mock Board exam for second year residents (2005-2011)

1. Predoctoral (Dental students): a. Senior Endodontic Course (Endo 548) (2005-2012) Topic on:

“Management of Dental Trauma” “Endodontic Surgery” “Newer Endodontic Technology” “Pulp Physiology and Pathology” “Periapical Pathosis”

b. Junior Endodontic Course (Endo 538) (05-2012) Topics on:

“Trauma to Teeth” “Endodontic Emergencies I & II” “Procedural errors” “Pulp Physiology, Pathology and stem cells”

c. Endodontic Preclinical lab and lectures (Endo 522) (05-2011)

d. Predoc Endodontic Clinic teaching (05-present) e. BSCI 521A Pain and Analgesia (07) Topic on “Dental pulp pain” f. Fundamental Microbiology (06) Topics on

“Host Response to Microbial Infection” “Stem Cells”

g. Found. 511: Dental Anatomy and Occlusion Topics on: “Histology of the Pulp” “The morphology of root canal system” CLINICAL AND DIDACTIC TEACHING (UCLA 1995-2004) A. Courses chaired or co-chaired:

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1. Postgraduate a. Advanced Endodontic Diagnosis and Treatment -DS 413c (chaired/lectured, 1999, 2000, 2002)

Time commitment: Spring quarters (course runs 1 h/week) Responsibility: Organize and select course contents and lecturers

Students: Third year dental students b. Clinical Endodontics-DS 462c (chaired, lectured, 1999, 2003; co-chaired, 2000)

Time commitment: Spring quarters (course runs 1 h/week) Responsibility: Organize and select course contents and lecturers

Students: Second year dental students c. Endodontic Clinic –CL 403.01 a,b,c,s (chaired, clinic, 1999, 2000)

Time commitment: Year round (clinics run everyday) Responsibility: Review and grade clinical cases completed by students

Students: Third year dental students d. Endodontic Clinic –CL 404.01 a,b,c,s (chaired, clinic, 1999, 2000)

Time commitment: Year round (clinics run everyday) Responsibility: Review and grade clinical cases completed by students

Students: Fourth year dental students e. Endodontic Technique Seminar (chaired, 1999-2004)

Time commitment: Summer quarter (3 h/session, 3-5 sessions/quarter) Responsibility: Teach hands-on advance Endodontic procedures on extracted teeth to

Endodontic Residents and Preceptors Teacher/Student Ratio (each session): average 1/6

B. Clinical teaching (participated):

Endodontic clinical teaching (1995-2004) Time commitment: Year round, 2-4 half days/week Responsibility: Teach in the Endodontic Clinic to both predoctoral dental students and

postgraduate endodontic students (residents). Teacher (faculty)/Student Ratio (each session): average 1/10 C. Didactic (course participated): (UCLA 1995-2004) I) Clinical Science:

Predoctoral Courses a. Preclinical Endodontic Lab Course I (DS 462b, 1995-2004)

Time commitment: Winter quarters (4 h/week) Responsibility: Teach second year dental students hands-on to perform endodontic

procedures on extracted teeth. Teacher (Faculty)/Student Ratio (each session): average 1/15

b. Preclinical Endodontic Lab Course I (DS 462b, 1995-2004)

Time commitment: Winter quarters (4 h/week)

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Responsibility: Teach second year dental students hands-on to perform endodontic procedures on extracted teeth.

Teacher (Faculty)/Student Ratio (each session): average 1/15

b. Preclinical Endodontic Lab Course II (DS 463s, 1998-2000) Time commitment: Summer quarters (1-2 h/week) Responsibility: Teach second year dental students hands-on to perform endodontic

procedures on extracted teeth. Teacher (faculty)/Student Ratio (each session): average 1/15

c. Advanced Endodontic Diagnosis and Treatment -DS 413c (lecture, 1996-2003) Time commitment: Spring quarters (1 h) (whole course runs 1 h/week) Responsibility: Lecture to third year dental students, topics on

“Restoration of endodontically treated teeth” (1996-1998) “Preparation for endodontic treatment” (1999-2002) “Endodontic instruments” (2000, 2003)

Teacher/Student Ratio (each session): average 1/85

d. Introduction to Pre-Clinical Endodontics-DS 462a (lecture, 2001-2004) Time commitment: Summer quarters (1 h/session) (whole course runs 1 h/week) Responsibility: Lecture to second year dental students, topics on: “Endodontic microbiology” Teacher/Student Ratio (each session): average 1/85

e. Clinical Endodontics-DS 462c (lecture, 1999-2004) Time commitment: Spring quarters (1 h/session) (whole course runs 1 h/week) Responsibility: Lecture to second year dental students, topics on:

“Pulpal and periapical pathoses” “Endodontic microbiology”

“Vital pulp therapy: direct and indirect pulp capping” “Antibiotics for Endodontics”

Teacher/Student Ratio (each session): average 1/85

f. Clinical Endodontics-DS 463c (lecture, 2002) Time commitment: Spring quarters (1 h/session) (whole course runs 1 h/week) Responsibility: Lecture to second year dental students, topic on:

“Endodontic pain control” Teacher/Student Ratio (each session): average 1/85

g. Treatment Planning II (1996) Time commitment: Summer quarters (1 h) (whole course runs 1 h/week) Responsibility: Lecture to second year dental students, topic on “Advanced Diagnostic

Methods” Teacher/Student Ratio (each session): average 1/90

Postdoctoral Courses:

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a. Basic and Current Literature Review in Endodontics (1995-2004) Time commitment: Year round (3 h/session/week, 2-5 sessions/quarter)

Responsibility: Review, critique and discuss literature that covers various aspects in the field of Endodontic with the Endodontic residents

Teacher/Student Ratio (each session): average 1/6

b. Clinical Case Review (1996-2004) Time commitment: Year round (2-3 h/session, 1-4 sessions/quarter)

Responsibility: Review, critique and discuss clinical cases completed by the Endodontic residents. This is a one-on-one teaching process.

Teacher/Student Ratio (each session): average 1/1 c. Introduction to Endodontic Research (1996-2003)

Time commitment: (1-3 h/session, 2-3 sessions/year) Responsibility: Introduce the concepts and methodologies of how to conduct an

original, scientific research to Endodontic residents. Teacher/Student Ratio (each session): average 1/6

d. Endodontic Research (1996-2004)

Time commitment: Year round (no regular schedule) Responsibility: Mentor and/or provide guidance to Endodontic residents to conduct

their research projects which are part of the requirements for the certificate training.

Teacher/Student Ratio (each session): average 1/6 e. Endodontic Technique Seminar (1996-2004)

Time commitment: Summer quarter (3 h/session, 2-5 sessions/quarter) Responsibility: Teach hands-on advance Endodontic procedures on extracted teeth to

Endodontic Residents and Preceptors Teacher/Student Ratio (each session): average 1/6

f. Endodontic Oral Mock Board exam for second year residents (1997-2004 UCLA)

Time commitment: Once a year (half-day) Responsibility: Prepare exam materials and evaluate graduating residents’ overall

accomplishment in didactic and clinical training. The format simulates the Board Certification process conducted by

the American Board of Endodontists Teacher/Student Ratio (each session): 3/1

II) Basic Science:

Predoctoral Courses: a. Oral Immunology (OB 472b, 2000-2001, 2004)

Time commitment: Winter quarters (1 h) Responsibility: Lecture to second year dental students, topic on “Endodontic

Immunology” Teacher/Student Ratio (each session): 1/80-90

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Postdoctoral Courses:

a. Oral Biology Course OB 275 (Molecular Biology) (1997) Time commitment: Fall quarter (1 h) Responsibility: Lecture to Graduate Oral Biology master and PhD students, topic on

“Post-Transcriptional Control of Gene Expression” Teacher/Student Ratio (each session): average 1/15

b. Molecular Biology of Oral Diseases (1999, 2002)

Time commitment: Winter quarters (1 h) Responsibility: Lecture to residents in Periodontics, topic on “Host Parasite

Interactions:Induction of Host Cytokines” Teacher/Student Ratio (each session): average 1/10

c. Basic Processes in Oral Biology (2010-2012, BU; 2013, UTHSC)

Time commitment: Spring quarters (1 h) Responsibility: Lecture to residents in on “Stem cells” and “Tissue engineering”

Teacher/Student Ratio (each session): average 1/20 COMMITTEES AND OFFICES HELD:

A. COMMITTEE SERVICE AT UCLA, Columbia U and Boston U, UT 2013- Curriculum committee (UT) 2013- Faculty development committee (UT) 2009-2011 Executive committee (CU, BU) 2009-2011 Clinical Finance Committee (BU)

Postdoctoral Curriculum Committee (BU) Merit increase task force ad hoc committee (BU)

2000-2004 School-Wide Space Planning Committee (UCLA) 1999-2004 Postgraduate Certificate and Residency Program Committee (UCLA) 2000-2001 Appointments, Promotions, and Appraisals Committee (observer) (UCLA) 1999-2000 Search Committee for Endodontic Chair (UCLA) 1997-1999 Research Advisory Committee (UCLA) 1997-2000 Oral Biology Fellowships Committee (UCLA) 1996-1997 Health and Safety Committee (UCLA) 1999-2003 Admission Committee interviewer (UCLA)

B. ADMINISTRATIVE RESPONSIBILITIES AT UCLA, CU and BU 2009-2011 Chair/Director, Department of Endodontic, Boston University 2009 Director, Division of Endodontics, Columbia University 2003-2004 Accreditation preparation as Director (Postgraduate Program),

Section of Endodontics, University of California, Los Angeles

1999-2004 Director, Postgraduate Program, Section of Endodontics University of California, Los Angeles

1999-2000 Acting Chair, Section of Endodontics

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University of California, Los Angeles 1996-2003 Research Director, Section of Endodontics

University of California, Los Angeles

C. INTERVIEWER FOR UCLA DDS CANDIDATES 1999-2001 2003-2004

VISITING PROFESSORSHIPS: 2009- Visiting Professor, Taipei Medical University, Taiwan, ROC 2007-2008 Visiting Professor, Kaohsiung Medical University, Taiwan, ROC INVITED LECTURES International:

1. “ Oral stem cells for regenerative medicine” (1.0 h), Seminar, National Taiwan University, Taipei, Taiwan, July 30, 2014.

2. “Oral stem cells for regenerative medicine” (1 h), Chongqing Medical University Dental Hospital, Chongqing, China, July 28, 2014.

3. “Functional neurogenesis of iPS cells derived from dental stem cells” (1.5 h), , International dental symposium, Taipei Medical University, Taipei, Taiwan, May 24, 2014.

4. “The missing concept in de novo pulp regeneration” ( 30 min) 15TH BIENNIAL CONGRESS ESE (Europ Soci Endodont) Lisbon 2013, Lisbon, Portugal, Sep 14, 2013.

5. “The missing concept in de novo pulp regeneration" (1.5 h) Federación dontológica Colombiana, Cali, Colombia S.A. Sept 7, 2013

6. “Stem cells, reprogramming and regenerative medicine” (1 h) International Symposium – “Stem cells, reprogramming and cell based therapy” (1 h), Military Medical Research Center, Institute of Transfusion Medicine, Lab of Regenerative Medicine, Beijing, China, May 24, 2013.

7. “Stem cells and regenerative medicine” (1.5 h), Keynote speaker, International dental symposium, Taipei Medical University, Taipei, Taiwan, May 18, 2013.

8. “Stem cells, reprogramming and guided differentiation” (1 h), Peking U School of Stomatology, Beijing, China, May 23, 2013.

9. Dental and cancer stem cells. Seoul National University School of Dentistry, Seoul, Korea, Oct 6, 2012.

10. “The coming era of mesenchymal stem cell therapy” (3 h) Cathay Hospital, Taipei, Taiwan, Oct 9, 2012.

11. “Induced pluripotent stem cells for regenerative medicine” (30 min) IADR/PER, Symposium, Helsinki, Finland. Sept 13, 2012.

12. “Stem cells for craniofacial and dental tissue regeneration" (4.0 h) Federación dontológica Colombiana, Bogotá Colombia S.A. May 11, 2012

13. “Current advancement of experimental and clinical regenerative endodontics” ( 30 min) 15TH BIENNIAL CONGRESS ESE (Europ Soci Endodont) ROME 2011, Rome, Italy, Sep 14, 2011.

14. “Stem cells for regeneration and therapy” (1 h), Peking U School of Stomatology Dept of Endodontics, Beijing, China, Sept 1, 2011.

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15. “Regenerative vs traditional endodontics” (1 h), Chi-Mei Hospital Dental Dept. Tainan, Taiwan, ROC, Aug 24, 2011.

16. “Progress on pulp/dentin regeneration – coming to clinics sooner than you think” (2.5 h), Taiwan endodontic association annual conference lecture, Taipei, Taiwan, R.O.C., August 20, 2011.

17. “The coming era of regenerative endodontics: what a dentist needs to know” (1 h), Association for Dental Sciences, Taipei, Taiwan, R.O.C., August 26, 2011.

18. “Dental pulp regeneration” (1 h) CDA (Canadian Dental Association Annual Conference), Nova Scotia, Canada, Aug 4, 2011

19. “Apexification: the end is now” and “Current updates on clinical endodontics” (half-day), University of Alberta, 10th Endodontic Day, Department of Dentistry, Edmonton, Alberta, Canada, May 1, 2010.

20. “Current progress on dental stem cells” (1 h), Association for Dental Sciences, Taipei, Taiwan, R.O.C., 2010.

21. “Cells, stem cells & reprogramming” (2.5 h) Taipei Medical University, Taipei, R.O.C. Nov 25, 2010.

22. “iPS cells – a new foundation in medicine.” (1.5 h) Taipei Medical University, 2nd Annual Conference on Tooth Banking, Stem Cell Research, and Development and their Clinical Applications. Taipei, May 30, 2010.

23. “Apexification: the end is now” (1.5 h), Hong Kong Endodontic Society, May 28, 2010. 24. “Recent development of pulp tissue regeneration.” (2 h) Hong Kong University Faculty of

Dentistry. Hong Kong, May 28, 2010. 25. “iPS cells and their clinical potential” (2 h) Peking University School of Stomatology,

Beijing, China, May 25, 2010. 26. “Stem cells and regenerative endodontics” (half-day), University of Alberta, 10th

Endodontic Day, Department of Dentistry, Edmonton, Alberta, Canada, May 1, 2010. 27. “Mesenchymal stem cells in dental and medical applications” (1 h) Fu Jen University,

Shinjhuan, Taiwan, ROC, 7/4/09. 28. “Mesenchymal stem cells in dental and medical applications” (1 h) Taipei Medical

University, School of Oral Medicine, Taipei, Taiwan, ROC, 7/3/09. 29. “Dental tissue-derived stem cells—biology and role in regenerative medicine” (1 h) Taipei

Medical University, School of Oral Medicine, Taipei, Taiwan, ROC, 7/2/09. 30. “Dental tissue-derived stem cells—biology and role in regenerative medicine” (1 h) Fourth

Military University, School of Stomatology, Xi’an, China, 6/29/09. 31. “Apexification: the beginning of its end”. National Taiwan University, Taipei, Taiwan, Nov

6, 08 32. “A Paradigm Shift in Endodontic Management of Immature Teeth -- Conservation of Stem

Cells for Regeneration" (45min) Annual Convention for American Association of Endodontists, Vancouver, British Columbia, Canada, 4/12/2008.

33. “Stem cell based therapy for dental and craniofacial tissues” Taipei Medical University, Taipei, Taiwan, Nov 7, 08.

34. “Stem cell banking for regenerative medicine” Taipei Cathay Hospital, Taipei, Taiwan, Nov 6, 08

35. “Stem cell based orofacial tissue regeneration” (1 h), National Taiwan University Dental School, Taipei, Taiwan, ROC, 7/05/2007.

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36. “Stem cell based orofacial tissue regeneration--research staff and fellow panel discussion” (3 h), Kaohsiung Medical University Dental Research Institute, Kaohsiung, Taiwan, ROC, 7/03/2007.

37. “Stem cell based orofacial tissue regeneration” (1 h), Kaohsiung Medical University Dental Research Institute, Kaohsiung, Taiwan, ROC, 7/03/2007.

38. “Pulp Tissue Engineering” (2-hour), Department of Dentistry, Cathay Hospital, Morning Meeting, Taipei, Taiwan, ROC, 3/2/06

39. “Clinical manifestations and the underlying mechanisms of endodontic diseases” (2-hour), National Defense Medical University, Taipei, Taiwan, ROC, 3/1/06

40. “Pulp Tissue Engineering” (2-hour), Taipei Medical University, Taipei, Taiwan, ROC, 2/27/06

41. “Endodontology: an integral part of biomedical science” (whole-day), Academy of Endodontology Republic of China, National Taiwan University, Taipei, Taiwan, ROC, 2/26/06

42. “Regenerative medicine for clinical endodontics” (1-hour), Department of Dentistry, Chi-Mei Hospital, Morning Meeting, Tainan, Taiwan, ROC, 2/22/06

43. “Mechanisms of Pulpal Pain” (2-hour), Department of Dentistry, Tainan Municipal Hospital, Tainan, Taiwan, ROC, 2/21/06

44. "Prospect of regenerative medicine for clinical endodontics" (1 h), Pulp Biology and Endodontics Graduate School, Tokyo Medical and Dental University, Tokyo, Japan April 6, 2005.

45. Prospective Cutting Edge Biotechnologies for Endodontics—tissue engineering and gene therapy” (1 h), U Toronto, School of Dentistry, Toronto, Canada, Jan. 10, 2005.

46. “Cutting Edge Biotechnologies for Endodontics--From Diagnosis to Treatment” (2 h), Uni Toronto, School of Dentistry, Toronto, Oct. 14, 2004.

47. “Molecular Basis of Endodontic Infection--Foundation for Diagnosis and Treatment” (half-day), University of Alberta, Department of Dentistry, Edmonton, Alberta, Canada, April 7, 2003.

48. “Pulpal Inflammation—The kinetics” (1-hour), Cathay Hospital Dental Department, Morning Meeting, Taipei, Taiwan, ROC, 1/10/99.

49. “Advanced concepts in cleaning and shaping with NiTi instruments” (1.5-hour), Cercle Parisien Endodontologie Appliquee (private study club), Paris, France, 6/30/98

50. “Current new advances in Endodontics” (1-hour), Dept. of Dentistry, National Taiwan University Hospital, Morning Meeting, Taipei, Taiwan, ROC, 1/8/98

51. “Special cases presentation in Endodontics” (1-hour), Department of Dentistry, Cathay Hospital, Morning Meeting, Taipei, Taiwan, ROC, 1/7/98

52. “Current new advances in Endodontics” (1-hour), Department of Dentistry at Veterans Administration General Hospital, Morning Meeting, Taipei, Taiwan, ROC, 1/6/98

53. “Current new advances in Endodontics” (2-hour), Special Lecture to dental students, Taipei Medical College, Taipei, Taiwan, ROC, 1/6/98

54. “Current new advances in Endodontics” (1-hour), Department of Dentistry, Ma-Jei Hospital, Morning Meeting, Taipei, Taiwan, ROC, 1/5/98

55. “Current new advances in Endodontics” (1-hour), Der-Wei Dental Clinic (Private study club), Taipei, Taiwan, ROC, 1/5/98

56. “Warm gutta-percha technique in Endodontics” (2-hour), Private study club, Kaohsiung, Taiwan, ROC, Dec. 1994.

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57. “The advantages of warm gutta-percha technique in Endodontics” (1-hour), National Cheng-Kung University Hospital, Tainan, Taiwan, ROC, Dec. 1994

58. “The Esthetics of Endodontics” (2-hour), Taipei Dental Association and Taipei Medical College Alumni Association, Taipei, Taiwan, ROC, Dec. 1994.

59. “Introduction of cleaning and shaping concepts for warm gutta-percha technique in Endodontics” (2-hour) Private study club, Taipei, Taiwan, ROC, Sept. 1989.

National:

1. “Regenerative dentistry” (1 h) Memphis Dental Society, Memphis, TN, Oct 16, 2014. 2. “Dental stem cells for tissue regeneration” (1 h) Oral Biology seminar series, UIC College of

Dentistry, Chicago, IL, April 15, 2014. 3. “Oral stem cells for regenerative medicine” (30 min) Faculty meeting, UTHSC, College of

Dentistry, Memphis, TN, Feb 11, 2014 4. “Dental stem cells for tissue regeneration” (1 h), AADR Memphis Chapter Fall seminar,

UTHSC, College of Dentistry, Memphis, TN, Nov 7, 2013. 5. “Immunoregulation and pathogenesis of Bone Resorption” and “Stem cells and regenerative

endodontics” (1.5 h), Bender, Seltzer & Grossman Academic Review of Endodontology (3-day review lecture series), U Penn, Philadelphia, PA, 9/27, 2013.

6. “Immunoregulation and pathogenesis of Bone Resorption” and “Stem cells and regenerative endodontics” (1.5 h), Bender, Seltzer & Grossman Academic Review of Endodontology (3-day review lecture series), Temple U, Philadelphia, PA, 9/22, 2012.

7. “Stem cells and regenerative endodonticsʺ (1.5 h) Annual Convention for American Association of Endodontists, Boston, MA, 4/21/2012.

8. “Bridging the basic science to clinical teaching and practice" (1.5 h) Annual Convention for American Association of Endodontists, Boston, MA, 4/19/2012.

9. “Progress on pulp and dentin tissue engineering and regeneration" (1.5 h) Annual Convention for American Association of Endodontists, Boston, MA, 4/21/2012.

10. “Immunoregulation and pathogenesis of Bone Resorption” and “Stem cells and regenerative endodontics” (1.5 h), Bender, Seltzer & Grossman Academic Review of Endodontology (3-day review lecture series), Temple U, Philadelphia, PA, 9//10, 2011.

11. “Dental stem cell markers” (30 min) The first International Conference on Dental and Craniofacial Stem cells. Columbia University, NY, April 27, 2011.

12. “Stem cells and regenerative dentistry” (1 h), Boston University, Boston, General Dentistry, Feb 15, 22, 2011.

13. “Regeneration endodontics: from present to future of dental medicine.“ Schilder Symposium, Organizer and speaker, Boston, MA, Oct 29, 2010.

14. “Immunoregulation and pathogenesis of Bone Resorption” (1.5 h), Bender, Seltzer & Grossman Academic Review of Endodontology (3-day review lecture series), U Penn, Philadelphia, PA, 10/2/2010.

15. “Stem cells and regenerative endodontics” (4 h), Boston University Endodontic Alumni Fall meeting, Scottsdale, AZ, Oct 16, 2010.

16. “Stem cells and regenerative endodontics” (4 h), Connecticut Academy of Endodontology, Connecticut, Oct 6, 2010.

17. “It was stem cell all along.” Keynote Speaker, Science Day, Boston University, School of Dentistry, Boston, MA, March 25, 2010.

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18. “Inflammation and Immunoregulation” (1.5 h) ” Stem cells and regenerative endodontics” (1 h) College of Diplomates and Columbia U Board Review Course. New York, NY, March 12-14, 2010.

19. “iPS cells reprogrammed from mesenchymal-like stem cells of dental tissue origin” (1 h) Dept of Molecular and Cell Biology seminar series, Boston U Dental Medicine, Oct, 09

20. “Immunoregulation and pathogenesis of Bone Resorption” (1.5 h), Bender, Seltzer & Grossman Academic Review of Endodontology (3-day review lecture series), Albert Einstein Medical Center, Philadelphia, PA, 9//09.

21. “Dental tissue-derived stem cells—biology and role in regenerative medicine” (1.0 h), University of Medicine and Dentistry of New Jersey, NJ, May 15, 09.

22. “Dental tissue-derived stem cells—biology and role in regenerative endodontics” (1.5 h), Annual Convention for American Association of Endodontists, Florida, April, 09.

23. “Stem cells and their clinical applications” (1 h) Research Day Guest Speaker, Southern Illinois University, IL, April 14, 09.

24. “Stem cell-based therapy for dental tissue regeneration” (1 h) Research Day Guest Speaker, Southern Illinois University, IL, April 14, 09.

25. “The applications of stem cells in apical papilla in pulp/dentin regeneration and bioroot regeneration” Regenerative Dentistry meeting, Nova Southeastern University, FL, Feb 13, 09.

26. “Immunoregulation and pathogenesis of Bone Resorption” (1.5 h), Bender, Seltzer & Grossman Academic Review of Endodontology (3-day review lecture series), Temple University, Philadelphia, PA, 9/28/08.

27. “Dental tissue-derived stem cells for regenerative endodontics” University of Pennsylvania, Philadelphia, PA, 9/10/08.

28. “Dental stem cell reprogramming” NIH/NIAMS, 7/08 29. “The Coming Era Of Regenerative Endodontics" Columbia University, New York,

12/7/07 30. "From Pink Pulp to Pink Gutta Percha to Pink Pulp Tissue -The Era Of Regenerative

Endodontics" Boston University Endodontic Alumni Annual Meeting, Boca Raton, Florida, 10/20/07. 

31. “Immunoregulation and pathogenesis of Bone Resorption” (1.5 h), Bender, Seltzer & Grossman Academic Review of Endodontology (3-day review lecture series), University of Pennsylvania, Philadelphia, PA, 9/28/07.

32. “Stem cells, tissue engineering and Endodontics“ (45 min), Annual Convention for American Association of Endodontists, Philadelphia, PA, 4/28/2007.

33. “Pathogenesis of Bone Resorption” (1.5 h), Bender, Seltzer & Grossman Academic Review of Endodontology (3-day review lecture series), Albert Einstein Medical Center, Philadelphia, PA, 9/8/06 -9/10/06.

34. “Pulp Tissue Engineering” (1-hour), NIH/NIAMS, Intramural Research – Cartilage Biology and Orthopedics Branch, Bethesda, MD, 8/16/06.

35. “Pulp Tissue Regeneration” (2-hour), Harvard University School of Dental Medicine, Boston, MA, 4/21/06

36. “Pulp Tissue Engineering” (1-hour), Boston University School of Dental Medicine, Boston, MA, 4/21/06

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37. “Pulp Tissue Engineering” (1-hour), Johns Hopkins University Dept. Biomedical Engineering, Baltimore, MD, 4/4/06

38. “Pulp Tissue Engineering” (1 h), SUNY Stonybrook, School of Dental Medicine, Stonybrook, New York, Sep. 29, 2005

39. “Pulp Tissue Engineering” (1 h), Boston University Endodontic Alumni Annual Meeting, Washington DC , 9/22/05.

40. “Tissue Engineering Technology for Pulp Tissue Regeneration and Beyond” (1 h), University of Maryland, Department of Endodontics, Baltimore, MD, Mar. 4, 2005.

41. “Tissue Engineered Models for Infection Studies” (1 h), NIH/NIDCR, Intramural Research -- Oral Infection and Immunity Branch, Bethesda, MD, Mar. 3, 2005.

42. “Prospective Cutting Edge Biotechnologies for Endodontics—Tissue Engineering and Gene Therapy” (1 h), Baylor College of Dentistry, TAMUSHSC, Departments of Endodontics, Dallas, TX, Dec. 17, 2004.

43. “Cutting Edge Biotechnologies for Endodontics--From Diagnosis to Treatment” (2 h), University of Maryland, Department of Endodontics, Baltimore, MD, Nov. 30, 2004.

44. “Cutting Edge Biotechnologies for Endodontics--From Diagnosis to Treatment” (2.5 h), Albert Einstein Medical Center, to Departments of Endodontics of both Albert Einstein Medical Center and University of Pennsylvania, Philadelphia, PA, Oct. 20, 2004.

45. “Cutting Edge Biotechnologies for Endodontics--From Diagnosis to Treatment” (2.5 h), NYU Department of Endodontics, New York, Oct. 18, 2004.

46. “Prospective cutting Edge Biotechnologies for Endodontics—tissue engineering and gene therapy” (1 h), SUNY Stonybrook, School of Dental Medicine, New York, Sep. 16, 2004.

47. “Cutting Edge Biotechnologies for Endodontics--From Diagnosis to Treatment” (1.5 h), Annual Convention for American Association of Endodontists, Anaheim, CA, May 7, 2004.

48. “Enhanced of Innate Immunity and Tissue Repair—Naturally Programmed or Man-Made” (1 hour), University of Southern California, Los Angeles, CA, 7/17/02.

49. “Enhanced Innate Immunity—Naturally Programmed and Man-Made” (1 hour), Center for Craniofacial and Molecular Biology, University of Southern California, Los Angeles, CA, 10/25/01.

50. “Molecular Control of Endodontic Infection” (30 min), UCLA School of Dentistry, Board of Counselors, Los Angeles, CA (4/25/01).

51. “Pulpal Inflammation—Little is Known” (1-hour) Boston University Endodontic Alumni Annual Meeting, Greenbrier, West Virginia, 10/22/99.

52. “Studies of ICAM-1 and IL-8 Expression in Oral Diseases” (1-hour) UCLA Dental Research Institute Seminar Series, Los Angeles, CA, 10-27-1998

53. “Upregulation of IgA Expression by Cytokines through Gene Activation and mRNA Stabilization” (1-hour) UCLA Dental Research Institute Seminar Series, Los Angeles, CA, 2-14-1995.

54. “Regenerative endodontics and tooth regeneration” (1 h), Boston University, General Dentistry Conference – update in general dentistry, April 9, 2010.

55. “Apexification: the beginning of its end”. BU Endo alumni Fall meeting, Oct, 09. 56. “Apexification: the beginning of its end”. Annual Convention for American Association of

Endodontists, FL, April, 09.

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57. “A Paradigm Shift in Endodontic Management of Immature Teeth -- Conservation of Stem Cells for Regeneration" (4 hr) Albert Einstein Medical Center, Philadelphia, PA, 3/6/08.

58. “A Paradigm Shift in Endodontic Management of Immature Teeth -- Conservation of Stem Cells for Regeneration" (1 hr) National Taiwan University, Taipei, Taiwan, ROC, 2/21/08.

59. “A Paradigm Shift in Endodontic Management of Immature Teeth -- Conservation of Stem Cells for Regeneration" (4 hr) Kaoshiung Medical University, Kaoshiung, Taiwan, ROC, 2/19/08.

60. “A Paradigm Shift in Endodontic Management of Immature Teeth -- Conservation of Stem Cells for Regeneration" (1 hr) Endodontic Opinion Leaders Forum, La Jolla, CA, 7/28/07.

61. “Immature teeth with periradicular periodontitis or abscess undergo apexogenesis – a paradigm shift” Chinese American Dental Association in Southern California Continuing Education Course, Los Angeles, CA, 6/07.

62. “Recent Advances in Clinical Endodontics” (2 h), UCLA Restorative and Endodontics interdivisional/sectional seminar/conference. Los Angeles, CA, Feb. 24, 2004.

63. “Current concept in cleaning and shaping” (1-hour), Dept. of Dentistry, Wan-Fang Hospital, Morning Meeting, Taipei, Taiwan, ROC, 11/11/99

64. “Current concept in cleaning and shaping and use of microscope” (1-hour), , Taipei Medical College Hospital, Morning Meeting, Taipei, Taiwan, ROC, 11/9/99

65. “Current new advances in Endodontics and its future prospects” (whole-day), Chinese American Dental Association in Southern California Continuing Education Course, Los Angeles, CA, 10/11/98

66. “Vertical condensation in root canal obturation” (1.5 hour) Dental Student Endodontic Study Club (UCLA), Los Angeles, CA, 10/5/98

67. “Current new advances in Endodontics and its future prospects” (whole-day), Academy of Endodontology Republic of China and Taipei Medical College Alumni Association, Continuing Education course, Taipei, Taiwan, ROC, 1/4/98

68. “The current new advances in Endodontics” (2-hour), Kaohsiung Dental Association, Kaohsiung, Taiwan, ROC, 12/30/97

69. “The current new advances in Endodontics” (4-hour), National Cheng-Kung University Hospital and Tainan Dental Association, Tainan, Taiwan, ROC, 12/27/97

70. “Introduction to warm gutta-percha technique” (2-hour) Chinese American Dental Association in Southern California Continuing Education Course, Los Angeles, CA, 8/24/97

71. “Special cases presentation” (15 min) Ed Nutting San Diego Endodontic Seminar, San Diego, CA, May, 1995

EDITORIAL APPOINTMENTS:

As member of Scientific Advisory/Editorial Board Journal of Dental Research (2014-) Stem cell research and therapy (2014-) Journal of Experimental and Clinical Medicine (2008-) Dental Hypothesis (2010-2011) Journal of Endodontics (2003-2011)

The Open Dentistry Journal (2006-2010)

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As regular reviewer for: Stem Cells and Development Tissue Engineering

Oral Diseases Journal of Endodontics Int Endodontic Journal Oral Surg. Oral Med. Oral Path. Oral Radiol. Endod. (2006-2009)

J Dent Res, Stem cells and development, 11, 12, 13 Stem cell reviews and reports, 10, 13 Med Micro Immun, Nov, 09 BMC Cell Biology, Nov, 09 Cytotherapy, Nov, 09 J Exp & Clinical Med, 09 Stem Cells and Development, September, 08; Sept, Nov, 09 Tissue engineering, June, 09 Journal of Endodontics, regular reviewer, 09, 10, 11, 12, 13 Journal of Endodontics, regular reviewer, January, Feb, March, April, May, Sept, 08 Journal of Endodontics, regular reviewer, January, April, June, Aug, Nov 07 Int. Endo J, Sept, 08 Clinical Medicine: Ear, Nose and Throat. June, 08 Archives of Oral Biology, June 08 Annals of Anatomy, Feb, 08 Archives of Oral Biology, Oct 07, 12 Oral Surg. Oral Med. Oral Path. Oral Radiol. Endod., September, 07; April, Sept, 08 Oral Micro Immunol, ad hoc reviewer, June, 07 J. Dental Research, reviewer, March, 07; Sept, 08, 09-12 Ad hoc review for the impact of an scientific article regarding dental stem cells and

bio-root engineering, Scientific American, December, 06 Cell Death and Differentiation, ad hoc reviewer, December, 06 Matrix Biology, ad hoc reviewer, November, 06 Journal of Endodontics, reviewer, February, April, July, September, 2006 Oral Diseases, regular reviewer, May, August, Oct., Nov., 2006 Journal of Endodontics, reviewer, January, February, May, July, December (3

manuscripts), 2005 Archives Oral Biology, ad hoc reviewer, October, 2004 Journal of Endodontics, reviewer, Jan, March, June, July, August, September, 2004 CDA Journal, reviewer, March, 2004 Journal of Gene Medicine, ad hoc reviewer, January, 2004 Cytokine, ad hoc reviewer, January, 2004 Journal of Endodontics, reviewer, April, May, October, 2003 Journal of Endodontics

Serve on Scientific Advisory Board, as regular reviewer, April 2003 Journal of Endodontics, nominated as a reviewer, January 2003 Journal of the California Dental Association – March, June, 2002 Journal of Infectious Diseases, ad hoc -- December, 2001 Journal of the California Dental Association -- January, September 2001 Journal of the California Dental Association – March, August, 2000

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Editor for textbooks 1. G T-J Huang and I. Thesleff “Stem cells in craniofacial development and regeneration”

(Wiley Blackwell), 2013. FELLOWS/GRADUATE STUDENTS TRAINED: Visiting Scholars 1. Xinli Zhang, MD, PhD (7/97-6/98) a) Country: P. R. China b) Institute: Dept of Pathology, Third Military Medical University, Chongqing c) Title at the Institute: Associate Professor d) Publications (Projects done in my lab):

i) Huang, G.T.-J.* Zhang, X and Park, N.-H., Increased ICAM-1 expression in transformed human oral epithelial cells: Molecular mechanism and functional role in peripheral blood mononuclear cell adhesion and lymphokine-activated-killer cell cytotoxicity. Int. J. Oncology, 17:479-486, 2000.

ii) Huang, G. T.-J.*, Chugal, N., Potente, A. P., and Zhang, X., Constitutive Expression of Interleukin-8 and Intercellular Adhesion Molecule-1 in Human Dental Pulps. Int. J. Oral Biol. 24(4):163-168, 1999.

iii) Huang, G. T.-J.*, Potente, A. P., Kim, J.-W., Chugal, N., and Zhang, X., Increased interleukin-8 expression in inflamed human dental pulps. Oral Surg. Oral Med. Oral Path. Oral Radiol. Endod., 88:214-20, 1999.

iv) Huang, G. T.-J.*, and Zhang, X., Immunohistochemical Analysis of Interleukin-8 and Intercellular Adhesion Molecule-1 in Human Gingival Epithelium. Int. J. Oral Biol., 24:7-16, 1999.

2. Sang Hyuk Park, DMD, MSD (4/01-12/02) a) Country: South Korea b) Institute: Dept of Conservative Dentistry (Endodontics), SungKyunKwan University, School of

Medicine, Seol Korea c) Title at the Institute: Clinical Instructor d) Projects being conducted in my lab:

(i) Pulp tissue engineering (ii) IL-8 and MCP-1 regulation by SP in human dental pulps

e) Publications (Projects done in my lab): (i) Patel, T., Park, S.H., Lin, L., Chiappelli, F. and Huang, G.T.-J.* Substance P Induces

Interleukin-8 Production from Human Dental Pulp Cells. Oral Surg. Oral Med. Oral Path. Oral Radiol. Endod. Oral Surg. Oral Med. Oral Path. Oral Radiol. Endod. 96(4): 478-485, 2003.

(ii) Park, S.H., Hsiao, G. and Huang, G.T.-J.* Role of Neuropeptides in the Regulation of Interleukin-8 and Monocyte Chemoattractant Protein-1 Expression in Human Dental Pulp. Int. Endodontic J. 37(3):185-192, 2004.

(iii) Patel, T.*, Park, S.H., Lin, L, and Huang, G.T.-J. Substance P Induces IL-8 and MCP-1 Production by Human Pulpal Cells. J. Endodont., (abs#PR43), 28(3):264, 2002.

(iv) Patel, T.*, Park, S.H., Lin, L, Chiappelli, F. and Huang, G.T.-J. Substance P, not Calcitonin Gene-Related Peptide, Induces Interleukin-8 Production by Human Pulpal Cells. J. Dent. Res., 81 (special issue A):A-44 (#0130), 2002. (Oral presentation)

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(v) G.T.-J. Huang, A. Toca*, H.N. Dang, S.H. Park, H.-B. Zhang, and S.K. Haake. HBD-2 secreted by gingival epithelial cells is resistant to degradation by P. gingivalis, J. Dent. Res. 81 (special issue A) :A-283 (#2213), 2002.

f) Project conducted served as a partial requirement for the PhD degree given by the scholar’s home country University in Korea. 3. Haibo Zhang, MD (4/01- 7/02) a) Country: P. R. China b) Institute: Cardiovascular Surgical Dept, 2nd Clinical Medical College of Harbin Medical

University, Harbin c) Title at the Institute: Resident d) Projects being conducted in my lab:

(i) Antimicrobial gene therapy (ii) Antitumor gene therapy

e) Publications (Projects done in my lab): (i) G.T.-J. Huang, A. Toca*, H.N. Dang, S.H. Park, H.-B. Zhang, and S.K. Haake. HBD-2 secreted by gingival epithelial cells is resistant to degradation by P. gingivalis, J. Dent. Res. 81 (special issue A) :A-283 (#2213), 2002. (ii) Huang, G. T.-J.*, Zhang, H.-B., Liu, L., Kim, D., and Ganz, T. A model for antimicrobial gene therapy--Demonstration of human -defensin-2 antimicrobial activities in vivo using a novel approach. Human Gene Therapy, 2002 Nov. (iii) Huang, G. T.-J*., Zhang H.-B., Kim, D., Park, S. H., Liu, L., and Ganz, T. Antimicrobial gene therapy: in vivo demonstration of human -defensin-2 antimicrobial activities. Mol Ther--Amer Soci Gene Therapy, 5(5):S258 (abs #788), 2002. (iv) G. T.-J Huang* H.N. Dang, H.-B. Zhang, and S. K. Haake. Differential Regulation of Cytokine Genes in Gingival Epithelial Cells Challenged by F. nucleatum and/or P. gingivalis. Microb. Pathog. 37(6):303-312, 2004.

f) Project conducted served as a partial requirement for the PhD degree given by the scholar’s home country University in China. 4. Xiaobing Tan, DDS (6/10- 6/11) a) Country: P. R. China b) Institute: Cardiovascular Surgical Dept, 2nd Clinical Medical College of Harbin Medical University, Harbin c) Title at the Institute: Attending dentist d) Projects being conducted in my lab: hES and iPS cell derived MSCs 5. Alejandro Iglesias Linares DDS (8/12- 9/12) a) Country: Spain b) Institute: Associate Professor of Pediatric Dentistry, Orthodontics and Dentofacial Orthopedics. School of Dentistry. University of Seville, Spain. Collaborator Researcher of the Institute of Biomedicine of Seville (IBIS). Department of Physiology. Neuroscience Research Group. University of Seville. Spain. c) Title at the Institute: Attending dentist d) Projects being conducted in my lab: Neurogenic potential of dental stem cells

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6. Wenhau Zhu DDS (2/14- 2/15) a) Country: China b) Institute: Beijing University School of Stomatology c) Title at the Institute: Attending dentist d) Projects being conducted in my lab: Pulp stem cells and regeneration. POSTDOC and STUDENTS supervised/mentored in my laboratory at UCLA, Columbia U, Boston U, UT. Posdotc 1. Ikbale El Ayachi, PhD (Oct 12 - Present) a) Title of Project: Neurogenesis of transgene free iPS cells b) Bioscience Research (UT) c) Role: mentor 2. Zongdong Yu, MD (July 2012 –March 2014) a) Title of Project: Characterization of periodontal ligament stem cells. b) Bioscience Research (UT) c) Role: mentor d) work published in Stem Cell Res & Therapy, 2012, Stem Cells Devel, 2013 3. Xiaoying Zou, DDS, PhD (Oct 10-Jan 12) a) Title of Project: iPS cells reprogrammed from dental mesenchymal cells. b) Endodontics (Boston U) c) Role: mentor d) work published in Stem Cell Res & Therapy, 12 4. Xing Yang, DDS, PhD (Feb 09- March 10) a) Title of Project: iPS cells reprogrammed from dental mesenchymal cells. b) Endodontics (Columbia U) c) Role: mentor d) work published in Stem Cells Devel, 2009, Stem Cell Res & Therapy, 12 PhD/DScD student 1. Audrey Lin, (6/02-05) a) Title of Project: Wound healing and antimicrobial gene therapy b) Biomedical engineering (UCLA) c) co-mentored with Dr. Ichiro Nishimura (project mainly conducted in Dr. Nishimura’s lab) 2. Mey Alhabib (9/09-present) a) Title of Project: Stem cell mediated dental tissue regeneration b) DScD in Endodontics (BU)

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c) Role: mentor d) work published in Stem Cells Devel, 2013 3. Candice Yang (7/10-6/11) a) Title of Project: Neurogenic potential of dental stem cells b) DScD in Endodontics (BU) c) Role: mentor d) work published in Stem Cell Res & Therapy, 2012 Master’s students 1. Chunyi Yin (8/2003-12/2004, MS completed) a) Title of Project: Study models for antimicrobial gene therapy b) Oral Biology MS student. c) Role: mentor 2. Cathy Vu (MS, 10/2002-12/04, completed) a) Title of Project: Parathyroid hormone regulation of PTH-induced fragment 12 expression in murine osteoblasts b) Endodontic resident/Oral Biology MS program (UCLA) c) Role: thesis committee member 3. David Han (certificate/MS research project, 10/00-6/02, MS completed) a) Title of Project: Cytokines and MHC class II expression in epithelial cell of periapical granulomas and cysts b) Endodontic resident/MS (UCLA). c) Role: co-mentored with Dr. Anna Jewett d) Publication: Han, D.C., G.T.-J. Huang, L.M. Lin, N. Warner, Gim, J.S. and A. Jewett.* Expression of MHC Class II, CD70, CD80, CD86 and pro-inflammatory cytokines is differentially regulated in oral epithelial cells following bacterial challenge. Oral Microbiol. Immunol., 18:350-358, 2003. 4. Tushar Patel, (DDS/MS student, 8/00-6/2001, MS, not completed-student withdrawn from MS program) a) Title of Project: IL-8 regulation by SP in human dental pulps b) Dental/MS Student (UCLA) c) Role: Mentor d) Research results published Oral Surg. Oral Med. Oral Path. Oral Radiol. Endod 5. Derek Ego-osuala (Endo certificate/MS, 9/07-5/2008, not completed) a) Title of Project: Periodontal ligament regeneration for avulsed teeth b) Endodontic resident, U Maryland. c) Role: Mentor 6. Dominick Alongi (Endo certificate/MS, 9/06-5/2009, completed) a) Title of Project: Effect of inflammation on pulp stem cell potency

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b) Endodontic resident, U Maryland. c) Role: Mentor d) work published in Regenerative Medicine, 2010 7. Philippe Gauthier (7/10-5/12, completed) a) Title of Project: Stem-cell based periodontal ligament regeneration b) MScD in Endodontics (BU) c) Role: mentor 8. Yaa Owusu, (11/12-6/2014, completed) a) Title of Project: Characterization of periodontal ligament stem cells from deciduous teeth. b) MScD in Pedodontics (UT) c) Role: mentor Residents 1. Jan Nguyen, D.D.S. (certificate research project, 10/95-8/96) a) Title of Project: A cytotoxic evaluation of boron-implanted nickel-titanium endodontic files b) Endodontic resident (UCLA). c) Study project published in Journal of Endodontics (abstract) and presented in the annual convention. J. Endodont., (abs #OR8) April, 1997 [Oral Presentation]. 2. Anthony Potente (certificate research project, 10/96-8/98) a) Title of Project: Expression of IL-8 and ICAM-1 in human dental pulps b) Endodontic resident (UCLA). c) Study project published in Journal of Endodontics (abstract) and presented in the annual convention. Results also published in Int. J. Oral Biol. 24(4):163-168, 1999 and in Oral Surg. Oral Med. Oral Path. Oral Radiol. Endod., 88:214-20, 1999. 3. Margaret Wingard (certificate research project, 10/96-8/98) a) Title of Project: role of IL-6 in the formation of periapical lesions b) Endodontic resident (UCLA). c) Research results published in Oral Surg. Oral Med. Oral Path. Oral Radiol. Endod 4. Michael Dryden (certificate research project, 10/98-6/00) a) Title of Project: Antimicrobial effect of gutta-percha on oral bacteria b) Endodontic resident (UCLA). 5. Cathy Vu (certificate research project, 10/99-8/00) a) Title of Project: Role of IL-8 on oral epithelial cell growth b) AEGD resident (UCLA) 6. James Chen (certificate research project, 10/02-6/04) a) Title of Project: Effect of culture systems on gene expression profile in dental pulp cells b) Endodontic resident (UCLA)

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7. Daniel Kim (certificate research project, 07/04-03/05) a) Title of Project: Pulp tissue engineering b) Endodontic resident (UCLA) Dental Students 1. Patrick Lee (dental student research, 11/95-11/96) a) Title of Project: Response of oral epithelial cells to Actinobacillus actinomycecometans invasion b) DDS student (UCLA). 2. Lee Arca (dental student research, 11/95-2/97) a) Title of Project: Response of oral epithelial cells to Porphyromonas gingivalis invasion b) DDS student (UCLA). c) Poster presentation at Annual Dental Student Research Presentation (1997, UCLA) 3. Dan Benjamin (student research, 8/97-2/98) a) Title of Project: Detection of IL-8 in human dental pulps b) DDS student (UCLA). c) Abstract of the research results selected as top 5 in the Dental Student Research Competition (1998, UCLA) 4. Cindy Wang (dental student research, 3/98-7/99) a) Title of Project: Detection of IL-8 in human dental pulps b) DDS student (UCLA). c) Abstract published in Dental Student Research Report (1999) 5. Michael Dote (dental student research, 6/98-7/99) a) Title of Project: Detection of IL-8 in human dental pulps b) DDS student (UCLA). c) Abstract published in Dental Student Research Report (1999) 6. William Chen (dental student research, 9/98-1/99) a) Title of Project: role of IL-6 in the formation of periapical lesions b) DDS student, UCLA 7. Jin Park (dental student research, 1/99-5/00) a) Title of Project: role of IL-6 in the formation of periapical lesions b) DDS student, UCLA c) Research results published: Oral Surg. Oral Med. Oral Path. Oral Radiol. Endod 8. Justin Hong (dental student research, 1/99-1/00) a) Title of Project: role of IL-6 in the formation of periapical lesions b) DDS student, UCLA c) Research results published: Oral Surg. Oral Med. Oral Path. Oral Radiol. Endod 9. Michael Do (dental student research, 1/00-6/00)

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a) Title of Project: role of IL-6 in the formation of periapical lesions b) DDS student, UCLA c) Research results published: Oral Surg. Oral Med. Oral Path. Oral Radiol. Endod 10. Tusha Patel (dental student research, 6/99-12/01) a) Title of Project: Regulation of IL-8 by SP in human dental pulps b) DDS student, UCLA c) Research results published Oral Surg. Oral Med. Oral Path. Oral Radiol. Endod 11. Daniel Kim (dental student research, 7/00-8/04) a) Title of Project: Expression of IL-8 and ICAM-1 by oral epithelial cells in response to Actinobacillus actinomycecometans and Porphyromonas gingivalis invasion b) UCLA graduate c) Research results published in:

(i) Huang, G. T.-J.*, Zhang, H.-B., Liu, L., Kim, D., and Ganz, T. A model for antimicrobial gene therapy--Demonstration of human -defensin-2 antimicrobial activities in vivo using a novel approach. Human Gene Therapy, 2002

(ii) Huang, G. T.-J*., Zhang H.-B., Kim, D., Park, S. H., Liu, L., and Ganz, T. Antimicrobial gene therapy: in vivo demonstration of human -defensin-2 antimicrobial activities. Mol Ther--Amer Soci Gene Therapy, 5(5):S258 (abs #788), 2002. 12. Grace Hsiao (Dental student research, 7/02-6/04) a) Title of Project: Regulation of IL-8 by SP in human dental pulps b) DDS student, UCLA. c) Research results published in Int. Endodon. J. 13. Jason Cho (Dental student research, 11/03-present) a) Title of Project: Pulp cells gene expression b) DDS student, UCLA. 14. Selina Chan (Dental student research, 7/03-12/04) a) Title of Project: Pulp stem cells isolation b) DDS student, UCLA. c) Publication: J Endodon, 2006 15. Irene Tam (Dental student research, 7/03-12/04) a) Title of Project: Pulp stem cells isolation b) DDS student, UCLA. 16. Kristina Shagramanova (Dental student research, 7/03-12/04) a) Title of Project: Pulp stem cells isolation b) DDS student, UCLA. c) Publication: J Endodon, 2006 17. Panaz Auribach (Dental student research, 7/03-12/04) a) Title of Project: Pulp stem cells isolation

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b) DDS student, UCLA. 18. Derek Egoosuala (Dental student research, 9/05-10/06) a) Title of Project: Pulp stem cells characterization b) DDS student, U Maryland. 19. Kimberley Chan (Dental student research, Apex Program, 1/10-2/11) a) Title of Project: ES gene expression by OFCD iPS cells b) DMD student, Boston University c) Award: Research won ADA/Dentsply award, BU Science Day, 2010. 20. Insun Yoon (Dental student research, Apex Program, 1/10-8/11) a) Title of Project: 3D model of dental stem cell attachment to MTA b) DMD student, Boston University c) Award: Poster 1st award, BU Science Day, 2011. 21. Chris Adkins (Dental student research, 9/2013-Present) a) Title of Project: Neurogenesis of dental iPS cells. b) DMD student, University of Tennessee. RESEARCH AND OTHER EXTERNAL SUPPORT:

A. RESEARCH FUNDING Extramural

NIH 1. a. Project title: Regeneration of clinically relevant orofacial tissues in pre-clinical models

b. Principal Investigator: Jeremy Mao c. Collaborators: George Huang et al

d. Funding agent: PHS/NIDCR (National Institute of Dental Craniofacial Research) e. Type: GO grant 5RC2DE020767

f. Proposed period: 8-1-09 to 6-30-11 g. Total cost: $1,037,466

2. a. Project title: Regeneration of Pulp-Dentin Development in Immature Permanent Teeth with Pulp Necrosis

b. Principal Investigator: Ken Hargreaves c. Consultants: George Huang et al

d. Funding agent: PHS/NIDCR (National Institute of Dental Craniofacial Research) e. Type: R34

f. Proposed period: 8-1-10 to 6-30-13 g. Direct cost: $150,000

3. a. Project title: Stem cell based therapy for regenerative endodontics b. Principal Investigator: George T.-J. Huang c. Collaborators : Songtao Shi et al

d. Funding agent: PHS/NIDCR (National Institute of Dental Craniofacial Research)

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e. Type: RO1 3R01DE019156-02S1 f. Proposed period: 8-1-09 to 6-30-11

g. Direct cost: $31,427 4. a. Project title: Stem cell based therapy for regenerative endodontics

b. Principal Investigator: George T.-J. Huang c. Collaborators : Songtao Shi et al

d. Funding agent: PHS/NIDCR (National Institute of Dental Craniofacial Research) e. Type: RO1 1R01DE019156-01

f. Proposed period: 8-1-08 to 6-30-13 (no cost extension to December 2014) g. Direct cost: $1,150,000 h. Indirect cost:$700,000

5. a. Project title: Antimicrobial Gene Therapy

b. Principal Investigator: George T.-J. Huang c. Funding agent: PHS/NIDCR (National Institute of Dental Craniofacial Research) d. Type: R21 1R21DE014585-01

e. Proposed period: 5-1-02 to 4-31-04 (no cost extension to 4-31-05) f. Direct cost: $200,000 g. Indirect cost: $ 87,497 h. Total cost: $ 287,497

6. a. Project title: Molecular control of ICAM-1 expression in oral cancer b. Principal Investigator: George T.-J. Huang c. Funding agent: PHS/NIDR (National Institute of Dental Research) d. Award #: RO3 (5R03DE012141-02) e Period: 1-1-97 to 12-30-98 (no cost extension to 12-30-99) f. Direct cost: $50,000 g. Indirect cost: $24,500 h. Total cost: $ 74,500

7. a. Project title: A novel herpesviral vector for oral gene delivery b. Principal Investigator: Hongyu Deng c. Collaborators: George T.-J. Huang et al

d. Funding agent: PHS/NIDCR (National Institute of Dental Craniofacial Research) e. Type: K22

f. Proposed period: 7-1-04 to 6-30-09 g. Direct cost: $600,000

Foundations (peer reviewed) 1. a. Project title: Candida Species as an Endodontic Pathogen in HIV+/AIDS Population b. Principal Investigator: Nadia Chugal c. Co-Investigators: George T.-J. Huang et al d. Funding agent: The Campbell Foundation (peer-reviewed) e. Award type: Research Grant

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f. Period: 7-1-00 to 6-30-03 g. Direct cost: $65,000

2. a. Project title: Antimicrobial Gene Therapy b. Principal Investigator: George T.-J. Huang c. Co-Investigator: Dr. Tomas Ganz

d. Funding agent: The Stein Oppenheimer Endowment Award (peer-reviewed) e. Type: Research Seed Grant f. Period: 2-1-01 to 1-30-03 g. Direct cost: $20,000

AAE Foundation (peer reviewed) Faculty Research grant

1. a. Project title: Stem cell based periodontal ligament regeneration for avulsed teeth b. Principal Investigator: George T.-J. Huang d. Funding agent: American Association of Endodontists Foundation

e. Type: Research grant f. Direct cost: $20,000

g. Proposed period: 1-1-09 to 12-30-09 (no cost extension to 6/30/14

2. a. Project title: Pulp tissue engineering b. Principal Investigator: George T.-J. Huang

c. Funding agent: American Association of Endodontists Foundation (peer-reviewed, won first award of proposals submitted by researchers)

d. Type: Research Grant e. Direct cost: $43,000 f. Proposed period: 1-1-06 to 6-30-09

3. a. Project title: Regulation of proinflammatory cytokines by substance P in dental pulps

b. Principal Investigator: George T.-J. Huang c. Funding agent: American Association of Endodontists Foundation (peer-reviewed) d. Type: Research Grant e. Direct cost: $16,000 f. Proposed period: 7-1-02 to 6-30-03 (no cost extension to 6-30-04)

4. a. Project title: Kinetics of Interleukin-8 Expression in Diseased Dental Pulps

b. Principal Investigator: George T.-J. Huang c. Funding agent: American Association of Endodontists Foundation (peer-reviewed) d. Award type: Research Grant e. Period: 7-1-98 to 6-30-99 (no cost extension to 6-30-00) f. Direct cost: $12,000

Resident research grants mentored 1. a. Project title: De novo regeneration of periodontal ligament using stem cell sheet

technique b. Principal Investigator: Philippe Gauthier

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c. Co-Investigator/Mentor: George T.-J. Huang d. Funding agent: American Association of Endodontists Foundation d. Type: Research Grant e. Direct cost: $16,470 (PI won best proposal as resident) f. Proposed period: 6-1-11 to 6-30-13

2. a. Project title: Characterization of subpopulations of dental pulp stem cells 

b. Principal Investigator: Mey Alhabib c. Co-Investigator/Mentor: George T.-J. Huang d. Funding agent: American Association of Endodontists Foundation d. Type: Research Grant e. Direct cost: $32,500 (highest amount as resident grant as of 2010) f. Proposed period: 6-1-10 to 6-30-12

3. a. Project title: Identification and isolation of stem cells in periapical granulation

tissue 

b. Principal Investigator: Toshinori Tanaka c. Co-Investigator/Mentor: George T.-J. Huang d. Funding agent: American Association of Endodontists Foundation d. Type: Research Grant e. Direct cost: $12,500 f. Proposed period: 6-1-09 to 6-30-10

4. a. Project title: In vitro maintenance of human dental pulp stem cell self-renewal

capability  b. Principal Investigator: Thai Pham c. Co-Investigator/Mentor: George T.-J. Huang d. Funding agent: American Association of Endodontists Foundation d. Type: Research Grant e. Direct cost: $15,000 f. Proposed period: 6-1-09 to 6-30-10

5. a. Project title: Age Influence on human Dental Pulp Stem Cell (hDPSC) properties

b. Principal Investigator: Jae Oh c. Co-Investigator/Mentor: George T.-J. Huang d. Funding agent: American Association of Endodontists Foundation d. Type: Research Grant e. Direct cost: $20,000 f. Proposed period: 6-1-09 to 6-30-10

6. a. Project title: Tissue regeneration potential of dental pulp stem cells from inflamed a. Project title: Effect of inflammation on pulp stem cell potency

b. Principal Investigator: Dominick Alongi c. Co-Investigator/Mentor: George T.-J. Huang d. Funding agent: American Association of Endodontists Foundation d. Type: Research Grant

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e. Direct cost: $24,000 (highest resident grant as of 2007) f. Proposed period: 6-1-07 to 6-30-08

5. a. Project title: Cytokines and HLA class II expression in epithelial cell of periapical granulomas and cysts

b. Principal Investigator: David C. Han c. Co-Investigator/Mentor: George T.-J. Huang d. Funding agent: American Association of Endodontists Foundation (peer-reviewed) e. Award type: Research Grant f. Period: 7-1-01 to 6-30-02 g. Direct cost: $8,256 6. a. Project title: Expression of Interleukin-8 in Normal and Diseased Dental Pulps b. Principal Investigator: Anthony P. Potente c. Mentor/Co-Investigator: George T.-J. Huang

d. Funding agent: G5188/American Association of Endodontists Foundation (peer-reviewed) e. Award #: 013437; Resident Grant (Anthony P. Potente) f. Period: 7-1-97 to 6-30-98 (no cost extension to 6-30-99) g. Direct cost: $2,008 7. a. Project title: Effect of interleukin-6 deficiency on the formation of periapical lesions in mice b. Principal Investigator: Margaret Wingard c. Mentor/Co-Investigator: George T.-J. Huang d. Funding agent: G5188/American Association of Endodontists Foundation (peer-reviewed) e. Award #/type: 013432; Resident Grant (Margaret Wingard) f. Period: 7-1-97 to 6-30-98 (no cost extension to 6-30-99) g. Direct cost: $3,620

Industry 1. a. Project title: periodontal ligament regeneration with stem cells b. Principal Investigator: George T.-J. Huang

c. Funding agent: Dentsply d. Type: Research Grant e. Direct cost: pending f. Indirect cost: g. Proposed period:

Intramural (UCLA) 1. a. Project title: Down-modulation of local immunity by P. gingivalis b. Principal Investigator: George T.-J. Huang c. Funding agent: UCLA d. Type: Academic Senate Grant e. Period: 7-1-02 to 6-30-03 f. Direct cost: $4,200

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2. a. Project title: A Model for Anti-microbial Gene Therapy b. Principal Investigator: George T.-J. Huang c. Funding agent: UCLA d. Type: Academic Senate Grant e. Period: 7-1-01 to 6-30-02 f. Direct cost: $4,500 3. a. Project title: Molecular Basis of Epithelial Cells in Immune System b. Principal Investigator: George T.-J. Huang c. Funding agent: UCLA d. Type: Academic Senate Grant e. Period: 7-1-00 to 6-30-01 f. Direct cost: $1,900 4. a. Project title: Mechanism of ICAM-1 down-regulation by P. gingivalis b. Principal Investigator: George T.-J. Huang c. Funding agent: UCLA d. Type: Academic Senate Grant e. Period: 7-1-99 to 6-30-00 f. Direct cost: $ 8,000 5. a. Project title: Host immune responses to oral neoplastic and infectious diseases b. Principal Investigator: George T.-J. Huang c. Funding agent: UCLA Academic Development (Account# 441930-19900- Huang) d. Type: Faculty Career Development Award (UCLA) e. Period: 6-1-98 to 5-30-99 f. Direct cost: $3,000 6. a. Project title: Mechanism of IL-8 down-regulation by P. gingivalis b. Principal Investigator: George T.-J. Huang c. Funding agent: UCLA (Account# 4-591960-19914-07) d. Type: Academic Senate Grant e. Period: 7-1-98 to 6-30-99 f. Direct cost: $ 5,200 7. a. Project title: Regulation of ICAM-1 and IL-8 by human gingival keratinocytes following bacteria invasion b. Principal Investigator: George T.-J. Huang c. Funding agent: UCLA (Account# 4-591960-19914-07) d. Type: Academic Senate Grant e. Period: 7-1-97 to 6-30-98 f. Direct cost: $ 3,000 8. a. Project title: Molecular control of ICAM-1 expression in oral cancer b. Principal Investigator: George T.-J. Huang c. Funding agent: UCLA (Account# 4-591960-19900-07)

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d. Type: Academic Senate Grant e. Period: 7-1-96 to 6-30-97 f. Direct cost: $ 3,900 9. a. Project title: Anti-microbial Gene Therapy b. Principal Investigator: George T.-J. Huang c. Co-investigators: Tomas Ganz, Ichiro Nishimura d. Funding agent: UCLA/Dentistry e. Type: opportunity research award f. Period: 7-1-01 to 6-30-02 g. Direct cost: $5,000 10. a. Project title: Anti-microbial Gene Therapy b. Principal Investigator: George T.-J. Huang c. Co-investigators: Tomas Ganz, d. Funding agent: UCLA Dental Research Institute e. Type: Research seed grant f. Period: 7-1-00 to 6-30-02 g. Direct cost: $10,000 11. a. Project title: Molecular Basis of Epithelial Cells in Immune System b. Principal Investigator: George T.-J. Huang c. Co-investigators: Tomas Ganz, Susan Haake d. Funding agent: UCLA/Dentistry e. Type: Overhead/opportunity research award f. Period: 7-1-00 to 6-30-01 g. Direct cost: $10,000 12. a. Project title: Mechanism of IL-8 downregulation by P. gingivalis b. Principal Investigator: George T.-J. Huang c. Co-investigators: Susan Haake, Howard Kuramitsu d. Funding agent: UCLA/Dentistry e. Type: Overhead/opportunity research award f. Period: 7-1-99 to 6-30-00 g. Direct cost: $10,000 13. a. Project title: IL-8 regulation in infected gingival epithelial cells b. Principal Investigator: George T.-J. Huang c. Funding agent: UCLA/Dentistry d. Type: Overhead/opportunity research award e. Period: 9-1-97 to 6-30-98 f. Direct cost: $7,000 14. a. Project title: Expression of cytokines and adhesion molecules by oral keratinocytes following bacteria invasion b. Principal Investigator: George T.-J. Huang

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c. Funding agent: UCLA/Dentistry d. Type: Overhead/opportunity research award e. Period: 7-1-96 to 6-30-97 f. Direct cost: $9,000 15. a. Project title: Expression of cytokines and adhesion molecules by oral keratinocytes in response to infection b. Principal Investigator: George T.-J. Huang c. Funding agent: UCLA/Dentistry d. Type: Start-up fund (Overhead/opportunity research award) e. Period: 10-1-95 to 6-30-96 f. Direct cost: $15,000

BOOKS AND BOOK CHAPTERS:

Book Chapters (invited) 1. Huang, G.T.-J., Lin, L; Recucci D. Chapter on The Management of Endodontic Infections in

Incompletely Developed Teeth, Endodontic Microbiology, Ed. by A. Fouad, 2nd Ed, 2014. Wiley & Blackwell.

2. Huang, G.T.-J & Zou X. iPS technologies for tissue Engineering. Wiley & Blackwell, in review.

3. M. Torabinejad and G. T.-J. Huang, Chapter: Regenerative endodontics, In Mineral Trioxide Aggregate, ed. by M. Torabinejad. Wiley & Blackwell. 2014.

4. M. Nakashima and G. T.-J. Huang, Chapter: Pulp and dentin tissue regeneration, in Stem cells in craniofacial development and regeneration. ed. by G. T.-J. Huang & I. Thesleff, Wiley & Blackwell. 2013

5. C. Morsczack, G. T.-J. Huang and S. Shi, Chapter: Stem cells of dental and gingival tissue origin. In Stem cells in craniofacial development and regeneration. ed. by G. T.-J. Huang & I. Thesleff , Wiley & Blackwell, 2013

6. G.T.-J. Huang, X Zou, X Yan, KJ Hewitt, Y Shamis & JA Garlick; Stem cells, induced pluripotent stem cells and their differentiation to specified lineage fates. In Stem cells in craniofacial development and regeneration, ed. by G. T.-J. Huang & I. Thesleff, Wiley & Blackwell, 2013

7. L.M. Lin, and G. T.-J. Huang, Chapter: Pathobiology of the periapex, Pathways of the Pulp, 10th ed. 2011.

8. L.M. Lin, and G. T.-J. Huang, Chapter: Pathobiology of the periapex, Pathways of the Pulp, 11th ed. 2013.

9. Huang, G.T.-J., Chapter on The Management of Endodontic Infections in Incompletely Developed Teeth, Endodontic Microbiology, Ed. By A. Fouad, 2009. Wiley & Blackwell

10. W.-J. Li, K. Gollapudi, D. P. Patterson, G. T.-J. Huang, R. S. Tuan* Chapter: Cell-based therapies for musculoskeletal repair. In Principles of Regenerative Medicine, eds, A. Atala, R. Lanza, J.A. Thomson, R.M. Nerem. 2008.

11. Fouad A.F. and Huang, G.T.-J. Chapter 9: Inflammation and Immu nological Response. Ingle’s Endodontics – 6th Ed. 2008.

12. J. M. Taboas, C. K. Kuo, G. T.-J. Huang, and Rocky S. Tuan*. Chapter 5, Growth Factors in Adult Stem Cell Based Tissue Engineering. In Translational Approaches in Tissue Engineering and Regenerative Medicine; Artech House, Co-Editors: Jeremy Mao, Gordana Vunjak-Novakovic, Antonios Mikos, Anthony Atala. 2007.

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13. Haake S.K. and Huang, G.T.-J., Molecular Biology of the Host-Microbe Interaction in Periodontal Diseases: Selected Topics. (Chapter) Clinical Periodontology, 9th Edition. Editors: Carranza FA, Newman MG, and Takei HH. W. B. Saunders Co., Philadelphia PA. 2002.

14. Kagnoff, M.F., Eckmann, L., Yang, S.-K., Huang, G.T.-J., Jung, H.C., Reed, S.L., Fierer, J., Intestinal Epithelial Cells: An Integral Component of the Mucosal Immune System (Chap. 6, p63-71). Essentials of Mucosal Immunology, ed. by Kagnoff and Kiyono, Academic press, San Diego, 1996.

Editor for textbooks G T-J Huang and I. Thesleff “Stem cells in craniofacial development and regeneration” Wiley Blackwell, 2013

Editorials

15. G T-J Huang and LM. Lin, Comments on the use of the term “revascularization” to describe an endodontic procedure. J. Endodont, May 2008.

PEER-REVIEWED JOURNAL ARTICLES:

Peer Reviewed Articles *Corresponding author(s) 1. Philippe Gauthier, Zongdong Yu, Ikbale El-Ayachi, Rayan Bahabri, Mey Al-Habib, Quynh T.

Tran, and George T.-J. Huang.* ALP+ human periodontal ligament stem cells possess greater stemness properties while having little association with cementogenic phenotype compared to ALP- population. Submitted.

2. Mohamed Jamal, Sami M. Chogle, Sherif M. Karam*, and George T.-J. Huang*. NOTCH3 is expressed in apical papilla and SCAP but not in SCAP undergoing osteogenic differentiation. In prep.

3. Xiaofei Zhu, Yu Wang, Yuan Liu, George T.-J. Huang, Chengfei Zhang.* Immunohistochemical and histochemical analysis of newly formed tissues in root canal space transplanted with dental pulp stem cells plus platelet-rich plasma. J Endodont, 2014.

4. M Al-Shahrani, E DiVito, CV Hughes, D Nathanson and GT.-J. Huang*. Enhanced removal of enterococcus faecalis biofilms in the root canal using sodium hypochlorite plus photon induced photoacoustic streaming: an in vitro study. Photomedicin and Laser Surgery, 2014.

5. A. A. Azim*, K. Azim, A. S. Deutsch, GT.-J. Huang, Acquisition of anatomical parameters concerning molar pulp chamber landmarks using CBCT, J Endodont, 2014.

6. A. A. Azim*, A. Lloyd, G. T.-J Huang. Management of longstanding furcation perforation using a novel approach. J Endodont, 2014.

7. E Shimizu, D Ricucci, J Albert, AS Alobaid, JL Gibbs, G T-J Huang, LM Lin*. Clinical, Radiographic, and Histological Observation of a Human Immature Permanent Tooth with Chronic Apical Abscess after Revitalization Treatment. J Endodont, e-pub, 2013

8. M. Al-Habib, Z. Yu & G. T.-J. Huang*. Small Molecules Affect Human Dental Pulp Stem Cell Properties via Multiple Signaling Pathways. Stem Cells Devel, e-pub 2013 nih

9. W Zhu, Xi Zhu, GT.-J. Huang, C Zhang*, GSP Cheung, WL Dissanayaka. Regeneration of dental pulp tissue in immature dog teeth with apical periodontitis using platelet–rich plasma and dental pulp stem cells. Int J Endo, 2013.

10. X. ZOU, H. YANG, X. TAN, Z. YU, X. YANG and G. T.-J. Huang*. Establishment of Transgene-Free iPS Cells Reprogrammed from SCAP for neurogenesis. Stem Cell Res Therap, E-Pub Oct, 2012. (Highlighted in ESC & iPSC News 7.43.) nih.

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(http://connexoncreative.com/publications/archives/ESC743.aspx) 11. X Zhu, C Zhang*, G. T.-J. Huang, G. S.P. Cheung, W. L. Dissanayaka, and W. Zhu,

Transplantation of Dental Pulp Stem Cells and Platelet-rich Plasma for Pulp Regeneration. J Endodont. E-Pub, Sept, 2012,

12. J. Wu, G. T.-J. Huang, Wenxi He, Ping Wang; Qian Jia; Liping Dong; Zhongying Niu, Longxing Ni*. Basic Fibroblast Growth Factor Enhances Stemness of Human Stem Cells from the Apical Papilla. , J Endodont. 2012, Nih CU, BU

13. W Guo, H Wang, S Zou, M Gu, F Wei, R Dubner,G. T.-J. Huang*, and K Ren*. Bone marrow stromal cells produce long-term pain relief in rat models of persistent pain. Stem Cells, June on-line, 2011. Nih maryland

14. J Liao, M Al Shahrani, M Al-Habib, T Tanaka, G. T.-J. Huang,* Cells Isolated from Inflamed Periapical Tissue Express Mesenchymal Stem Cell Markers and are Highly Osteogenic. J. Endodont, on-line June, 2011. Nih BU

15. V. T-K Yamagishi*, C. D. Torneck, S. Friedman, G. T-J Huang, M. Glogauer. Blockade of tlr2 inhibits p. Gingivalis suppression of mineralized matrix formation by human dental pulp stem cells. J. Endodont, May, 2011. Nih M, CU, BU

16. G T-J Huang*, Apical cyst theory: a missing link. Dental Hypothesis, 1(2):76-84, 2010 Oct 5. BU nih

17. X. Wang, B Thibodeau, M Trope, LM. Lin, and G. T.-J. Huang* Histological Characterization of Regenerated Tissues in Canal Space after Revitalization/ Revascularization Procedure of Immature Dog Teeth with Apical Periodontitis. J Endodont Epub 2009. PMID: 20003936 (Journal cover page). CU

18. D. J. Alongi, T. Yamaza, Y. Song, A. Fouad, E. Romberg, S. Shi, R. S. Tuan and George T.-J. Huang*. Stem/Progenitor Cells from Inflamed Human Dental Pulp Remtain Tissue Regenerative Potential. Regen Med, on-lineEpub, May 2010. Nih PMID:20465527 Maryland

19. X. Yan, H. Qin, C. Qu, RS Tuan, S. Shi, and G. T.-J. Huang* iPS cells reprogrammed from mesenchymal-like stem/progenitor cells of dental tissue origin. Stem Cells Devel, On-line EPub Oct 1, 2009. PMID: 19795982.(Quoted by Mesenchymal Stem Cells News 2009) nih (#2 most read article of Stem Cells Devel as of Dec, 2010) (invited to compete for 12th Royan international research award, 2011.) M, CU, BU

20. F. Djouad, W. M. Jackson, B.E. Bobick, S. Janjanin3, Y. Song, G. T.-J Huang, R.S. Tuan*

Activin A expression regulates multipotency of mesenchymal progenitor cells. Stem Cell Res Ther. On-line May, 2010 , nih Maryland

21. G.T.-J. Huang*, T. Yamaza, L.D. Shea, F. Djouad, N. Kuhn, R.S. Tuan and S. Shi. Stem/progenitor Cell-Mediated De Novo Regeneration of Dental Pulp with Newly Deposited Continuous Layer of Dentin in an In Vivo Model. Tissue Engineering, Sept, 2009 Epub. PMID: 19737072 nih (#1 most read article of Tissue Eng as of Dec, 2010) Maryland

22. Feng F, Akiyama K, Liu Y, Yamaza T, Wang TM, Chen JH, Wang BB, Huang GT, Wang S, Shi S*. Utility of PDL progenitors for in vivo tissue regeneration: a report of 3 cases. Oral Dis. 2010 Jan;16(1):20-8. PMID: 20355278 (Best paper of Oral Dis in 2010)

23. Wataru Sonoyama,; Yi Liu,; Takayoshi Yamaza, Rocky S. Tuan, Songlin Wang, Songtao Shi, and George T.-J. Huang*, Characterization of Apical Papilla and its Residing Stem Cells from Human Immature Permanent Teeth –A Pilot Study. J Endodont. 34(20, 166-71, 2008. (Cover page) PMID: 18215674 (most cited paper in JOE within 5 yrs after publication, interviewed by JOE, 2012)

24. Huang GTJ, Lee HW, Lee HS, Lee GH, Huh SY, Choi GW, Park SH*. Localization of substance P-induced upregulated interleukin-8 expression in human dental pulp explants. Int Endod J. 2007 Nov 12; [Epub ahead of print] PMID: 18005045

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25. L.-H. Chueh and G. T.-J. Huang* Immature teeth with periradicular periodontitis or abscess undergoing apexogenesis – a paradigm shift. J Endodont. 2006 Dec;32(12):1205-13. Epub 2006 Oct 13Dec, 2006 (Cover page) PMID: 17174685. (Selected by the editor for media outreach; interviewed by Alan Mozes at HEALTHDAY, NY Times syndicate, news article published in various health news internationally; interviewed by LA Times Today and Scientific American)

http://yourtotalhealth.ivillage.com/stem-cell-technique-could-help-kids-avoid-root-canal.html http://www.ndri.com/article/root_canal_therapy__endodontic_treatment_an_alternative_techniqu

e_for_restoring_your_children_strong_tooth_-178.html http://www.washingtonpost.com/wp-dyn/content/article/2006/12/21/AR2006122101043.html http://www.dentaltribune.com/dt/common/includes/pdf_view_public.php?query=usendo/0107/et_

us_0107_0203.pdf 26. C. Yin, H.N. Dang, F. Gazor, and G. T.-J. Huang*. Mouse salivary gland and human -

defensin as a study model for antimicrobial gene therapy--technical considerations. Int. J. Antimicrob. Agent,. 2006. Oct;28(4):352-60. Epub 2006 Sep 11. PMID: 16963233

27. G. T.-J. Huang*, K. Shagramanova and S. W. Chan, Formation of Odontoblast-Like Cells from Cultured Pulp Cells on Dentin In Vitro. J Endodont 2006, Nov. 32(11): 1066-73. PMID: 17055908

28. Huang, G. T.-J.*, Sonoyama, W., Chen, J. and Park, S. H, In vitro characterization of human dental pulp cells –different isolation methods and culturing environments. Cell Tissue Res 324:225-36, 2006; Epub Jan. 2006. PMID: 16440193

29. C. Yin, Hoa N. Dang, H-B Zhang, F. Gazor, D. Kim, O. E. Sorensen, and G.T.-J. Huang*. Capacity of Human β-Defensin Expression in Gene-Transduced and Cytokine-Induced Cells. Biochem. Biophys. Res. Comm. 2006 Jan 6;339(1):344-54. Epub 2005 Nov 15. PMID: 16298338

30. G. T.-J Huang* H.N. Dang, H.-B. Zhang, and S. K. Haake. Differential Regulation of Cytokine Genes in Gingival Epithelial Cells Challenged by F. nucleatum and/or P. gingivalis. Microb. Pathog. 37(6):303-312, 2004. (Selected as the top 25 hottest articles (12th place) on ScienceDirect.com within the journal) PMID: 15619426

31. G.T.-J. Huang*, H.-B. Zhang, Chunyi Yin and S.H. Park. Human -defensin-2 gene transduction of dental pulp cells: A model for pulp antimicrobial gene therapy. Int. J. Oral Biol. Mar, 29(1) 7-12, 2004.

32. Park, S.H., Hsiao, G. and Huang, G.T.-J.* Role of Neuropeptides in the Regulation of Interleukin-8 and Monocyte Chemoattractant Protein-1 Expression in Human Dental Pulp. Int. Endodontic J. 37(3):185-192, 2004. PMID: 15009408

33. Han, D.C., G.T.-J. Huang, L.M. Lin, N. Warner, Gim, J.S. and A. Jewett.* Expression of MHC Class II, CD70, CD80, CD86 and pro-inflammatory cytokines is differentially regulated in oral epithelial cells following bacterial challenge. Oral Microbiol. Immunol., 18:350-358, 2003. PMID: 14622340

34. Patel, T., Park, S.H., Lin, L., Chiappelli, F. and Huang, G.T.-J.* Substance P Induces Interleukin-8 Production from Human Dental Pulp Cells. Oral Surg. Oral Med. Oral Path. Oral Radiol. Endod. 96(4): 478-485, 2003.

35. Huang, G. T.-J.*, Zhang, H.-B., Liu, L., Kim, D., and Ganz, T. A model for antimicrobial gene therapy--Demonstration of human -defensin-2 antimicrobial activities in vivo. Human Gene Therapy, 13:2017-2025, Nov 20, 2002. PMID: 12489997

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36. Huang, G. T.-J.,* Do, M., Wingard, M., Park, J. S., and Chugal, N., Effect of interleukin-6 deficiency on the formation of periapical lesion after pulp exposure in mice. Oral Surg. Oral Med. Oral Path. Oral Radiol. Endod., 92(1):83-8, 2001. PMID: 11458250

37. Huang, G.T.-J.,* Kim, D., Lee, J. K.-H., Kuramitsu, H. K. and Kinder Haake, S. Interleukin-8 and Intercellular Adhesion Molecule-1 Regulation in Oral Epithelial Cells by Selected Periodontal Bacteria: Multiple Effects of Porphyromonas gingivalis via Antagonistic Mechanisms. Infect Immun. 69(3):1364-1372, 2001. PMID: 11179300

38. Huang, G.T.-J.* Zhang, X. and Park, N.-H., Increased ICAM-1 expression in transformed human oral epithelial cells: Molecular mechanism and functional role in peripheral blood mononuclear cell adhesion and lymphokine-activated-killer cell cytotoxicity. Int. J. Oncology, 17:479-486, 2000. PMID: 10938387

39. Han, Y.*, Shi, W., Huang, G.T.-J, Haake, S.K., Park, N.-H., Kuramitsu, H., Genco, R.J., Interactions between periodontal bacteria and human oral epithelial cells: Fusobacterium nucleatum adheres to and invades epithelial cells. Infect. Immun., 68(6):3140-3146, 2000. PMID: 10816455

40. Huang, G. T.-J.*, Chugal, N., Potente, A. P., and Zhang, X., Constitutive Expression of Interleukin-8 and Intercellular Adhesion Molecule-1 in Human Dental Pulps. Int. J. Oral Biol. 24(4):163-168, 1999.

41. Huang, G. T.-J.*, Potente, A. P., Kim, J.-W., Chugal, N., and Zhang, X., Increased interleukin-8 expression in inflamed human dental pulps. Oral Surg. Oral Med. Oral Path. Oral Radiol. Endod., 88:214-20, 1999. PMID: 10468466

42. Huang, G. T.-J.*, and Zhang, X., Immunohistochemical Analysis of Interleukin-8 and Intercellular Adhesion Molecule-1 in Human Gingival Epithelium. Int. J. Oral Biol., 24:7-16, 1999.

43. Huang, G.T.-J.*, Kinder-Haake, S., Kim, J.-W and Park, N.-H., Differential expression of interleukin-8 and intercellular adhesion molecule-1 by human gingival epithelial cells in response to Actinobacillus actinomycetemcomitans or Porphyromonas gingivalis infection. Oral Micro. Immun., 13:301-309, 1998. PMID: 9807122

44. Huang, G.T.-J.*, Kinder-Haake, S. and Park, N.-H., Gingival epithelial cells increase interleukin-8 secretion in response to Actinobacillus actinomycetemcomitans challenge. J. Periodont., 69:1105-1110, 1998. PMID: 9802708

45. Huang, G.T.-J., Lenon, K. and Kukuruzinska, M.A.*, Characterization of multiple transcripts of the hamster dolichol-P-dependent N-acetylglucosamine-1-P transferase suggests functionally complex expression. Mol. Cell. Biochem., 181:97-106, 1998. PMID: 9562246

46. Huang, G.T.-J., Eckmann, L., Savidge, T.C. and Kagnoff, M.F.*, Infection of human intestinal epithelial cells with invasive bacteria upregulates apical intercellular adhesion molecule-1 (ICAM-1) expression and neutrophil adhesion. J. Clinical Investigation, 98(2):572-583, 1996. PMID: 8755670

47. Eckmann, L., Huang, G.T.-J., Smith, J.R., Morzycka-Wroblewska E. and Kagnoff, M.F.*, Increased transcription and coordinate stabilization of mRNAs for secreted immunoglobulin alpha heavy chain and kappa light chain following stimulation of immunoglobulin A expressing B cells. J. Biological Chemistry, 269(52):33102-9, 1994 (The first two authors contributed equally to this work) PMID: 7806538

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48. Mota, O.M., Huang, G.T.-J., Kukuruzinska, M.A.*, Developmental regulation and tissue-specific expression of hamster dolichol-P-dependent N-acetylglucosamine-1-P transferase (GPT). Biochem. Biophys. Res. Comm., 204(1)284-91, 1994. PMID: 7945372

49. Huang, G.T.-J., Schilder, H.* and Nathanson, D., Effects of moisture content and endodontic treatment on some mechanical properties of human dentin. J. Endodont., 18(5):209-15, 1992. PMID: 1402574

Review Articles (peer reviewed) 50. GT.-J. Huang* and F.G. Godoy, The missing concept in de novo pulp regeneration. J

Dent Res CROBM 2014. (invited) 51. L.M. Lin* & G. T.-J. Huang. Radicular Responses of Immature Permanent Teeth with

Necrotic Pulp to Apexification Therapy. In prep. 52. L.M. Lin* & G. T.-J. Huang. Regeneration of Dentin-Pulp Complex with

Revitalization/Revascularization Therapy: Challenge and Hope. Int Endo J. 2013. 53. GT.-J. Huang*, M Al-Habib, P. Gauthier. Challenges of stem cell based pulp and dentin

regeneration – a clinical perspective. Endodontic Topics (invited), 28:51-60, 2013. 54. Huang GT. The coming era of regenerative endodontics: what an endodontist needs to

know.(invited) Alpha Omegan. 2011 Spring;104(1-2):46-51. PMID: 21905366 BU 55. Huang GT. Dental pulp and dentin tissue engineering and regeneration: advancement and

challenge. (invited), Front Biosci (Elite Ed). 2011 Jan 1;3:788-800. PMID:21196351. Nih BU

56. G. T.-J. Huang* Induced pluripotent stem (iPS) cells – a new foundation in medicine. J Exp Clini Med (invited), 2(5), 202-217, 2010. Nih BU

57. G. T.-J. Huang*. Pulp and Dentin Tissue Engineering and Regeneration -- Current Progress. Regenerative Med (invited), 4(5) 697-707, 2009. PMID: 19761395. Nih CU

58. G. T.-J. Huang*. Apexification: the beginning of its end. Int Endo J, June 2009. PMID: 19549154 Maryland

59. G. T.-J. Huang*, S. Gronthos and S. Shi. Mesenchymal stem cells derived from dental tissues vs. those from other sources: their biology and role in regenerative medicine (invited). J Dent Res CROBM, Sep 2009. (cover page) PMID: 19767575. Nih (top 50 most-frequently read article of JDR, top #4 as of Jan 2011) nih

60. G. T.-J. Huang*. A Paradigm Shift in Endodontic Management of Immature Teeth: Conservation of Stem Cells for Regeneration. J Dent. 2008 Apr 15 [Epub ahead of print]. PMID: 18420332.

61. Huang G.T-J*, Sonoyama W, Liu Y, Liu H, Wang S, Shi S. The hidden treasure – stem cells in apical papilla and their potential role in pulp/dentin regeneration and bio-root engineering. J. Endodont, Available online 17 April 2008. PMID: 18436023 doi:10.1016/j.joen.2008.03.001

62. L. M. Lin*, G. T.-J. Huang, P. A. Rosenberg, Proliferation of Epithelial Cell Rests, Formation of Apical Cysts, and Regression of Apical Cysts after Periapical Wound Healing. J. Endodont, 33(8), 908-916, 2007. PMID: 17878074.

OTHER PUBLICATIONS: Abstracts (oral or poster presentation at scientific meetings)

*Presenter 1. El Ayachi I, Yu Z, Zou X, O’Connell K, Huang GT-J. Generation of Functional Neurons

from Transgene-free human SCAP-IPS cells. IADR J. Dent. Res 2014 Oral presentation and Session Chair.

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2. M.A. Alhabib*, and G. T.-J. Huang. Reduced DPSC Proliferation Via Altered Cell Cycle by Small Molecules. J. Dent. Res. 2013 (AADR/IADR)

3. P. Gauthier*, Z. Yu, R. Bahabri, M.A. Alhabib, and G.T. HUANG. Human ALP+ PDLSCs Possess Higher Percentage of STRO-1+ and CD146+ (#3014), J. Dent. Res. 2013 (AADR/IADR).

4. O. ATTAR*, B. MIZRAHI, G.T.J HUANG, C.V. HUGHES, and D. NATHANSON. Controlled-Release Antimicrobial System in Endodontic Sealers - In Vitro Study. J. Dent. Res., 2013 (AADR/IADR).

5. X. ZOU* & G. T.-J. Huang, Neurogenic Potential of Oral VS Other Stromal/Stem Cells. J. Dent. Res., 2013 (AADR/IADR).

6. B.M.F. CHAN*, A.G. MAOINE, J. CAINE, E. KNIGHT, A. SMITH, Y. SHAMIS, B. GERAMI-NAINI, G.T.J HUANG, and J.A. GARLICK. Dental Pulp Stem Cell-Epithelial Interactions in 2D and 3D Co-culture. J. Dent. Res., 2013 (AADR/IADR).

7. M.A. Al Shahrani*, E. DiVito, C.V. Hughes, G.T.J. Huang, D. Nathanson. Efficacy of Photon Induced Photoacoustic Streaming in Elimination of Enterococcus Faecalis Colonized in the Root Canal Systems. J Endodont, 2013.

8. P. Gauthier*, G.T.J. Huang. Expression of cementum markers CAP and CEMP1 in Periodontal Ligament Stem Cells under osteoinductive conditions. J Endodont, 2013. (Gauthier got 2nd price for the oral presentation as resident)

9. M. Jamal*, S. Chogle, H. Goodis, Y. Greish, N. AE Gomaa, GTJ. Huang, S. Karam.. SCAP Characterization and its Growth and Differentiation on Polycaprolactone-Based Scaffolds. J Endodont, OR13, 2013.

10. M. JAMAL*, S. CHOGLE, H. GOODIS, Y.E. GREISH, M.A. AL-HABIB, G. T.-J. Huang, and S.M. KARAM . SCAPs Characterization and their Interaction with PCL-based Scaffolds. J. Dent. Res., 2012 (IADR)

11. X. ZOU*, H. YANG1, X. TAN1, D.N. KOTTON2, and G. T.-J. Huang. Neural Differentiation of Transgene-Free iPS Cells Reprogrammed from SCAP. J. Dent. Res. 2012 (IADR)

12. M.A. AL-HABIB*, and G. T.-J. Huang, Increased DPSC Stemness by SC1 via Targeting Signal Transduction Pathways. J. Dent. Res. 2012 (IADR)

13. H. JAHA*, Y. OHYAMA2, A. ALMEHMADI2, S. VENKITAPATHI2, R. ALJAMAAN2, S. SUZUKI3, Y. MOCHIDA2, and G. T.-J. Huang. The effect of DSP on pulp cell and bone. J. Dent. Res. 2012 (IADR)

14. M. Al-Habib* & G. T.-J. Huang. Effects of Small Molecules on Dental Pulp Stem Cell Properties. J. Dent. Res., 2012 (AADR)

15. W Guo*, H Wang, S Zou, M Gu, F Wei, R Dubner, G. T.-J. Huang, and K Ren. Bone marrow stromal cells produce long-term pain relief in rat models of persistent pain. ISCCR 2011.

16. M. Al-Habib* & G. T.-J. Huang. Characterization of Subpopulations of Dental Pulp Stem Cells. J Endodont. 2011.

17. I. Yoon*, M. Al-Habib, G.T.-J. Huang. 3D model of dental stem cell attachment to MTA. J. Dent. Res., 2011 (AADR/IADR).

18. V. TOM-KUN YAMAGISHI*, C.D. TORNECK, S. FRIEDMAN, G.T.-J. HUANG, and M. GLOGAUER. TLR2-Blockade Inhibits P.gingivalis Suppression of Mineralized Matrix Formation by hDPSCs. J. Dent. Res., 2011 (AADR/IADR) (accepted, withdrawn by presenter)

19. K. Chan*, J. Liao, X. Yan, H. Qin, S. Shi and G. T.-J. Huang. Characterization of iPS cells reprogrammed from stem cells with BCOR mutation. J. Dent. Res., 2011 (AADR/IADR)

20. J. Liao, M. Al Shahrani*, M. Al‐Habib, T. Tanaka, G. T.‐J. Huang. Characterization of Human Mesenchymal Cells in  Inflamed  Periapical  Tissue.  J. Dent. Res., 2011 (AADR/IADR)

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21. M. Al-Habib* & G. T.-J. Huang. Enhancement of Dental Pulp Stem Cell Stemness using small molecules J. Dent. Res., 2011 (AADR/IADR) (won Pulp Biology & Regeneration Group travel award) (session co-chair)

22. X. Yan, H. Qin, Q Qu, S. Shi, and G. T.-J. Huang. Human iPS cells reprogrammed from stem cells with BCOR mutation. J. Dent. Res., 2010 (IADR). (session co-chair)

23. X. Yan1, H. Qin2, R.S. TUAN3, S. SHI2 G. T.-J. Huang1* . Teratoma formation by iPS cells reprogrammed from dental stem cells. J. Dent. Res., 2010 (AADR).

24. H. Qin, X. Yan, S. Shi, and G. T.-J. Huang. iPS cells generated from OFCD patient as a study model for developmental disorder. Int Soci Stem Cell Res., 2010.

25. D.J. Alongi, T. YAMAZA, Y. Song, R.S. TUAN, S. SHI. And G.T.-J. HUANG* Clonogenic stem/progenitor cells from inflamed dental pulps remain capable of tissue regeneration. Int Soci Stem Cell Res., 2009

26. G.T.-J. HUANG*, TAKAYOSHI YAMAZA, L.D. SHEA, F. DJOUAD, and R.S. TUAN, S. SHI. Regeneration of human pulp-/dentin-like tissues in emptied root canal space. J. Dent. Res., 2009. (session co-chair)

27. D.J. Alongi*, A.F. Fouad, G.T.-J. Huang. Effect of inflammation on pulp stem cell potency. J Endodont. 2009. (Won resident award – D. J. Alongi)

28. G.T.-J. HUANG*, L.D. SHEA, F. DJOUAD, S. SHI, and R.S. TUAN. Stem cell-mediated de novo regeneration of human dental pulp. TERMIS (Tissue Engineering Regenerative Medicine International Society), San Diego, CA, 2008. (Session co-chair).

29. G.T.-J. HUANG*, S. SHI, F. Djouad and R.S. TUAN. Lentiviral Vector-Mediated Transduction of Human Mesenchymal Stem Cells. J. Dent. Res., 2008.

30. G.T.-J. HUANG*, S. SHI and R.S. TUAN. Characterization of Dental Stem Cells from Pulp and Apical Papilla in vitro. J. Endodont., AAE, 2008.

31. G.T.-J. HUANG* Pulp Stem Cells for Pulp Regeneration. J. Endodont., 07-E-38-AAE, 2007. 32. G.T.-J. HUANG*, D. EGO-OSUALA, S.-H. PARK, L.D. SHEA, and R.S. TUAN. Pulp Stem

Cells Grown in Scaffolds and on Dentin. J. Dent. Res., #1447, 2007.(session chair) 33. C. Yin*, H.N. Dang, F. Gazor, and G.T.-J. Huang. Mouse salivary gland model for

antimicrobial gene therapy--technical considerations. J. Dent. Res., 2006 34. K. Shagramanova*, S. W. Chen, P. Aurasteh, I. Tam, G.T.-J. Huang. In vitro formation of

odontoblast-like cells on dentin. J. Dent. Res., 2006. 35. C. Yin* and G.T.-J. Huang. HBD-2 expression levels between naturally induced vs

genetically transduced cells. J. Dent. Res., 2005. 36. S.-H. Park, E.-J. Jung, E.-M. Rhim*, G.-W. Choi, G.-H. Lee, and G.T.-J. Huang, TNF-α

induces MMPs in pulp, gingival, and periodontal ligament cells. J. Dent. Res., 2005 37. S.-H. Park*, K.-J. Kim, S.-J. Park, S.-Y. Huh, H.-W. Lee, and G.T.-J. Huang. Substance P

and CGRP Induce Interleukin-8 by Human Gingival Cells. J. Dent. Res., 2005 38. D. Kim*, S.H. Park, and G.T.-J. Huang. Human pulp tissue engineering: an in vivo study

model. J. Dent. Res., 2005 39. James C. Chen* and G.T.-J. Huang. Characterizations of primary human pulpal stem cell

cultures -- A comparison of different methodologies and passages of cells. J. Endodont. 30(4):274 (abs#PR5), 2004.

40. M. Jung, S. Park*, and G.T.-J. Huang. Immunohistochemical Detection of Interleukin-8 in Substance P-Stimulated Dental Pulp. J. Dent. Res. 83 (spec issue A) #1670, 2004.

41. D. Kim*, O. Sorensen, H.-B. Zhang, T. Ganz and G.T.-J. Huang. HBD-3 Transduction of Cultured Human Cells using Retroviral Vectors. J. Dent. Res. 83 (spec issue A) #2722, 2004.

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42. Audrey Lin,* Cortino Sukotjo, Kevin Song, Takahiro Ogawa, Ben Wu, George T.-J. Huang, Ichiro Nishimura. Transfection of wit-3.0 accelerates wound contraction. J. Dent. Res. 83 (spec issue A) #1160, 2004.

43. H.N. Dang*, A. Toca, H.-B. Zhang S. K. Haake and G. T.-J Huang. Differential Regulation of Cytokine Genes in Gingival Epithelial Cells Challenged by F. nucleatum and/or P. gingivalis Analyzed with cDNA Array. J. Dent. Res. 82 (special issue B):B-226 (#1715), 2003.

44. S.H. Park, G. Y.W Hsiao* and G.T.-J. Huang. Role of Neuropeptides in Regulating the Expression of IL-8 and MCP-1 in Human Dental Pulp. J. Dent. Res., 82 (special issue B):B-185 (#1387), 2003.

45. Park, S. H*, and Huang, G. T.-J. Characterization of Pulp Cell Behaviors Cultured in Collagen Matrix. J. Dent. Res., 82 (special issue B):B-252 (#1927), 2003.

46. G.T.-J. Huang*, S.H. Park, and H.-B. Zhang. Transduction of human dental pulp cells with retroviral vectors carrying HBD-2 cDNA. J. Dent. Res.., 82 (special issue B):B-46 (#0272), 2003. [Oral presentation]

47. S.A. Kinder Haake, S. Hunt Gerardo and G.T.-J. Huang. Fusobacterium nucleatum: A Beneficial Pathogen? Anaerobe (2002) 8, 115–174.

48. Huang, G. T.-J*., Zhang H.-B., Kim, D., Park, S. H., Liu, L., and Ganz, T. Antimicrobial gene therapy: in vivo demonstration of human -defensin-2 antimicrobial activities. Mol Ther--Amer Soci Gene Therapy, 5(5):S258 (abs #788), 2002.

49. Han, D.C.*, G.T.-J. Huang, L.M. Lin, N. Warner, Gim, J. and A. Jewett. The role of epithelium in periapical pathosis: A model system. J. Endodont., (abs#OR30), 28(3):242, 2002.

50. Patel, T.*, Park, S.H., Lin, L, and Huang, G.T.-J. Substance P Induces IL-8 and MCP-1 Production by Human Pulpal Cells. J. Endodont., (abs#PR43), 28(3):264, 2002.

51. Huang, G. T.-J *, and Haake, S. K. Differential Regulation of IL-8 mRNA in Gingival

Epithelial Cells by F. nucleatum or P. gingivalis. J. Dent. Res., 81 (special issue A):A-231 (#1758), 2002. [*Presenter was the program chair for the oral session]

52. Patel, T.*, Park, S.H., Lin, L, Chiappelli, F. and Huang, G.T.-J. Substance P, not Calcitonin Gene-Related Peptide, Induces Interleukin-8 Production by Human Pulpal Cells. J. Dent. Res., 81 (special issue A):A-44 (#0130), 2002. (Oral presentation)

53. Han, D.C.*, G.T.-J. Huang, L.M. Lin, N. Warner, and A. Jewett. Induced HLA Class II/CD54 cell surface expression and cytokine production in oral epithelial cells challenged by selected oral bacteria in vitro. J. Dent. Res., 81 (special issue A):A-490 (#4009), 2002. (Oral presentation)

54. G.T.-J. Huang, A. Toca*, H.N. Dang, S.H. Park, H.-B. Zhang, and S.K. Haake. HBD-2 secreted by gingival epithelial cells is resistant to degradation by P. gingivalis, J. Dent. Res. 81 (special issue A) :A-283 (#2213), 2002.

55. Lin, L.*, Chugal, N, and Huang, G.T.-J., Endodontic failure: contributing factors. J. Dent. Res. 80 (special issue IADR):654 (#1018), 2001.

56. Huang, G.T.-J.,* Kim, D., Kuramitsu, H. K. and Kinder Haake, S. Antagonistic Regulation of IL-8 mRNA in Gingival Epithelial Cells by Porphyromonas gingivalis.. J. Dent. Res. 80 (special issue IADR):537 (#0084), 2001. (Oral Presentation)

57. Huang, G. T.-J., Kim, D.*, Liu, L., and Ganz, T. Functional Human -Defensin-2 Secreted from NIH/3T3 Cells Transduced with Retrovirus Carrying HBD-2 Gene. J. Dent. Res. 80

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(special issue IADR):679(#1224), 2001. (D. Kim received IADR student travel award to present at IADR in Japan)

58. Huang, G. T.-J., Do, M., Park, J. S., Wingard, M. and Chugal, N.* Depletion of Interleukin-6 Accelerates the Formation of Periapical Lesions after Pulp Exposure. J. Dent. Res. 80 (special issue IADR):680 (#1225), 2001.

59. Dryden, M., Kim, D., and Huang, G. T.-J.*. Anti-microbial effects of gutta-percha on oral plaque. J. Endodont., (abs#PR10), March, 27(3):234, 2001.

60. Huang, G. T.-J.*, Kim, D., Liu, L. and Ganz, T. A model for antimicrobial gene therapy. 2001 Keystone Symposia, Gene Therapy 2001: A Gene Odyssey, Snowbird, Utah. (Poster presentation).

61. Huang, G. T.-J.,* Lee, J. K.-H., Kim, D., Kuramitsu, H. K. and Haake, S. K. Mechanism of IL-8 regulation in gingival epithelial cells challenged with P. gingivalis. J. Dent. Res. 79 (special issue):176 (#261), 2000.

62. Huang, G. T.-J., Chugal, N.,* Potente, A. P., and Zhang, X. Constitutive expression of interleukin-8 and intercellular adhesion molecule-1 in normal and inflamed human dental pulps. J. Dent. Res. 79 (special issue):392 (#1987), 2000.

63. Huang, G. T.-J.*, Lee, J. K.-H., Kuramitsu, H. K. and Haake S. K. Reduced IL-8 protein expression with increased IL-8 mRNA level in porphyromonas gingivalis infected epithelial cells. Cold Spring Harbor Laboratory Meeting: Microbial Pathogenesis and Host Response. Cold Spring Harbor, NY, 1999. (Poster presentation)

64. Huang, G. T.-J.*, and Zhang, X. Immunohistochemical Localization of IL-8 and ICAM-1 in Normal and Inflamed Human Gingival Epithelium. J. Dent. Res., 78 (special issue B):188 (Abst # 664), 1999.

65. Potente, A. P.*, Kim, J.-W., Zhang, X. and Huang, G. T.-J., Expression of interleukin-8 in normal and diseased dental pulps. J. Endodont., (abs#OR39), April, 24(4):281, 1998. (Selected as top twelve abstracts submitted by resident (Potente) to American Association of Endodontists 55th annual session for oral presentation)

66. Potente, A. P., Chugal, N.*, Kim, J.-W., Zhang, X. and Huang, G. T.-J., Detection of interleukin-8 in normal and inflamed human dental pulps. J. Dent. Res., 77 (special issue B):799 (Abst # 1340), 1998.

67. Han, Y.W.*, Huang, G. T.-J., Ngok, F.K., Kinder Haake S., Camargo, P., Park, N.H. and Shi, W., Interactions between periodontal bacteria and human gingival epithelial cells. J. Dent. Res., 77 (special issue B):1031 (Abst # 3197), 1998

68. Huang, G.T.-J.*, Hsu, W.L. and Park, N.-H., Increased ICAM-1 expression on transformed human oral epithelial cells mediates lymphocyte adhesion and cytotoxcity. J. Dent. Res., 77 (special issue B):767 (Abst # 1084), 1998 [Oral Presentation].

69. Kagnoff, M.F., Eckmann, L., Huang, G., Yang, S.K., Kim, J.M. Intestinal epithelial responses to enteroinvasive bacteria: The proinflammatory gene program and apoptosis FASEB Journal Vol 12 (4,) Pages A362,1998.

70. Nguyen, J.*, Serene, T. and Huang, G.T.-J., In vitro biocompatiblity analysis of boron-implanted nickel-titanium. J. Endodont. (abs #OR8) April, 1997 [Oral Presentation].

71. Huang, G.T.-J.*, Chung, D.H., Kinder-Haake, S. and Park, N.-H., Coordinate regulation of ICAM-1 and IL-8 by human gingival keratinocytes following periodontal bacteria invasion. J. Dent. Res., 76:53 (abs#315) special issue, 1997 [Oral Presentation].

72. Huang, G.T.-J.* and Park, N.-H., Altered ICAM-1 expression in transformed human oral epithelial cells. J. Dent. Res., , 76:53 (abs#2144) special issue, 1997 [Oral Presentation].

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73. Nguyen, J.*, Huang, G.T.-J. and Serene, T., Cytotoxicity evaluation of boron-implanted nickel-titanium. J. Dent. Res., 76:53, special issue (abs#2513), 1997.

74. Huang, G.T.-J.*, Eckmann, L., Fierer, J. and Kagnoff, M.F., Increased ICAM-1 expression on human colon epithelial cells in response to bacterial invasion. Gastroenterology, 108:A-404 (abstract#1616), 1995 [Oral Presentation].

75. Huang, G.T.-J.*, Eckmann, L., Fierer, J. and Kagnoff, M.F., Human colon epithelial cells upregulate ICAM-1 expression following bacterial invasion. Clin. Immunol. Immunopathol., 76(1):S86 (abstract #504), 1995 [Oral Presentation].

76. Kagnoff, M.F.*, Eckmann, L., Huang, G.T.-J., Kim, P.H., Jung, H., Fierer, J. and Morzycka-Wroblewska, E., Cytokines regulate IgA production and provide early signals for the activation of immune and inflammatory response in the mucosal environment. J. Cell. Biochemistry, Suppl. 19A:234 (#J1-007), 1995.

77. Lennon, K., Huang, G.T.-J, Kukuruzinska, M.A. Molecular basis of hamster ALG7 transcript heterogeneity. J. Dent. Res 74: 196-196, sp. iss. si 1995.

78. Huang, G.T.-J.*, Eckmann, L. and Kagnoff, M.F., Differential use of polyadenylation sites of secreted immunoglobulin alpha heavy chain from a single AAUAAA poly(A) signal. Faseb J. 8(4):A255 (abstract #1477), 1994.

79. Mota, O.M.*, Huang, G.T.-J., Kukuruzinska, M.A., The ALG7 gene expression during postnatal development of submandibular gland. J. Dent. Res., (abstract #1537), 1993.

80. Huang, G.T.-J.* and Kukuruzinska, M.A., Multiple polyadenylation signals in the 3’-untranslated sequences of hamster salivary ALG7 gene. J. Dent. Res., 72:648 (abs #1061), 1992.

81. Huang, G.T.-J.* and Kukuruzinska, M.A., Molecular cloning and characterization of the hamster salivary ALG7 gene. J. Dent. Res., 71:264 (abs# 1264), 1992 [Oral Presentation].

82. Huang, G.T.-J.* and Kukuruzinska, M.A., Expression of the first N-glycosylation gene in salivary glands. J. Dent.Res., 70:312 (abstract # 374), 1991.

83. Huang, G.T.-J.*, Schilder, H. and Nathanson, D., Effects of moisture content and endodontic treatment on some mechanical properties of human dentin. J. Dent. Res., 70:439 (abs # 1389), 1991.

84. Huang, G.T.-J.*, Schilder, H. and Nathanson, D., Effects of endodontic treatment on the mechanical properties of human dentin. J. Endodont., 17 (4):194 (abs # 30), 1991. [Oral Presentation]

Symposium presentations 1. G.T.-J. HUANG (speaker), Dental pulp regeneration and stem cells of the apical papilla, sponsored by Pulp Biology and Regeneration group, Thursday, April 2, 2009: 8:00 AM-9:30 AM, Location: C123 (Miami Beach Convention Center) IADR/AADR 2009.

2. G.T.-J. HUANG (speaker), Induced pluripotent stem cells – new foundation for medicine. March 17, AADR/IADR, 2011. San Diego, CA.

3. G.T.-J. HUANG (speaker), Stem cell based therapy for regenerative endodontics (replaced original speaker who withdrew) March 18, AADR/IADR, 2011. San Diego, CA.

4. G.T.-J. HUANG (speaker), Revitalization/revascularization vs regeneration of pulp and dentin. April AADR, 2012. Tampa, FL

5. G.T.-J. HUANG (speaker), Characteristics of dental stem cell derived iPS cells. IADR, June 20, 2012. Iguacu, Brazil.

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Symposium organization (Program chair) 1. Stem cells, reprogramming, immunomodulation and cancer, AADR/IADR, March 17,

AADR/IADR, 2011. San Diego, CA. 2. Translation of Stem Cell Biology To Craniofacial Regeneration: Challenges and

Opportunities. March 18, AADR/IADR, 2011. San Diego, CA 3. Stem cell niches and induced pluripotent stem cells for craniofacial regeneration. IADR,

June 20, 2012. Iguacu, Brazil.

Thesis 1. Molecular Cloning and Characterization of Hamster Multiple ALG7 Transcripts. Doctor of

Science (D.Sc.) in Oral Biology, Boston University, 1992 2. The Effects of Moisture Content and Endodontics Treatment on Some Mechanical Properties

of Human Dentin. Master of Science in Dentistry (M.Sc.D.) in Endodontics, Boston University, 1989.

Media coverage of research work

Journal of Endodontics, podcasts interview, May 2012 http://www.jendodon.com/content/podcasts?TPSTOKEN=44.z%2F%2FQ3YwVLDBSswulkkTwxOD5QYVKb%2BMWaGgfowCpuGR8Y3k3SsuTYQ%3D%3D AAE Pulp Online, 2011 http://www.aae.org/welcome/pulparchive/onlinePULP0211.html Dentistry IQ, 2011 http://www.dentistryiq.com/articles/2011/07/stem-cells-used-to-relieve-mouth-face-pain.html Boston Globe, Nov, 2010. http://www.boston.com/business/healthcare/articles/2010/11/22/boston_scientists_see_big_potential_in_stem_cells_found_in_teeth/ BU today, Jan, Nov 2010 http://www.bu.edu/today/node/11853 http://www.bu.edu/today/node/10243 http://us.bioeden.com/broke-a-tooth-grow-it-back-bu-today/ http://stemsave.wordpress.com/ The Scientist, Feb, 2009 http://www.the-scientist.com/blog/display/57148/ Health Day News, 2006 http://news.healingwell.com/index.php?p=news1&id=536529

LICENSURE: 2012- Restricted Dental License (Tennessee) 2009-2012 Restricted Dental License (Massachusetts) 2009-2009 Restricted Dental License (New York)

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2005-2008 Teacher’s License (Maryland State) 1990-Present California State Dental License (active) 1989-Present Florida State Dental License (active) 1987-Present Taiwan, Republic of China, Dental License (inactive) 1985-1986 Taiwan, Republic of China, Dental License (active) SOCIETY MEMBERSHIPS: International society for Stem Cell Research (2009-present) International society for stem cell research (2009-2012) American/International Association of Dental Research (1990-present) American Association of Endodontists (1986-present)

UCLA Dental Research Institute (1996-2004) PRIVATE SECTOR APPOINTMENTS: 2003-2004 Consultant, Discus Dental 2009-Present Science Advisor: StemSave HONORS/AWARDS: 2004 Won first award of research proposals submitted by faculty researchers

Funding agent: American Association of Endodontists Foundation (peer-reviewed) 1998 Faculty Career Development Award, University of California, Los Angeles 1997- Diplomate, American Board of Endodontics 1992-1994 National Research Service Award (NIH/NIDDK) 1989-1992 Training Grant Recipient for D.Sc. Degree (NIH/NIDR) MILITARY SERVICE: 1983-1985 Military Service, Taiwan, Republic of China PRACTICE/PROFESSIONAL EXPERIENCE: 1985-1986 Private Practice in General Dentistry, Taipei, Taiwan, Republic of China (ROC) OTHER: CONTINUING EDUCATION AT UCLA, Columbia U, Boston U

1. “Endodontic management of immature teeth – conservation of stem cells for regeneration” Boston University, March 12 (3 hrs), 2010.

2. “Endodontic management of immature teeth – conservation of stem cells for regeneration” Continuing Education Course, Columbia U, Feb 27, 09 (1 h) .

3. “Introduction to warm gutta-percha technique in Endodontics” (1-hour lecture and 5-h bench-top instruction) Endodontic Continuing Education Course, UCLA School of Dentistry, Los Angeles, CA, 11-21-1998 (Presenter: self).

4. “Introduction to warm gutta-percha technique in Endodontics” (1-hour lecture and 4-h bench-top instruction) Endodontic Continuing Education Course, UCLA School of Dentistry, Los Angeles, CA, 8-15-1998 (Presenter: self).

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5. “Introduction to warm gutta-percha technique in Endodontics” (1.5-hour lecture and 4-h bench-top instruction) Endodontic Continuing Education Course, UCLA School of Dentistry, Los Angeles, CA, 10-4-1997 (Presenter: self).

6. “Introduction to warm gutta-percha technique in Endodontics” (1.5-hour lecture and 4-h bench-top instruction) Endodontic Continuing Education Course, UCLA School of Dentistry, Los Angeles, CA, 8-2-1997 (Presenter: self).

7. “Introduction to warm gutta-percha technique in Endodontics” (1.5-hour lecture and 4-h bench-top instruction) Endodontic Continuing Education Course, UCLA School of Dentistry, Los Angeles, CA, 3-8-1997 (Presenter: self).

8. “Introduction to warm gutta-percha technique in Endodontics” (0.5-hour lecture and 4-h bench-top instruction) Endodontic Continuing Education Course, UCLA School of Dentistry, Los Angeles, CA, 9-21-1996 (Presenter: self).

OTHER LECTURES ORGANIZED AT UCLA, Columbia U, Boston U

1. Co-organizer, Schilder/Gianelly Symposium, Boston University, (1 day) Oct 29, 2010. 2. Initiator and organizer of the lecture “Endodontic access cavity—the critical step for success”

(8-12 am), March 17, 1998 (Presenter: Dr. Yves Yana, Paris, France). 3. Initiator and organizer of the lecture “Use of NiTi rotary instruments for endodontic

treatment” (5:30-8:30 pm), March 22, 2000 (Presenter: Dr. Robert Augsburger, Tulsa, OK). 4. Initiator and organizer of a Dental Research Seminar. “Epithelial cells: an integral

component of the mucosal immune system.” (1-hour) 10-14-1997 (Presenter: Dr. Martin Kagnoff, UCSD, La Jolla, CA)

5. College of Diplomates and Columbia U Board Review Course. New York, NY, March 12-14, 2010.

6. Initiator and organizer of the Endodontic Microsurgery Continuing Education Course (to be held in Nov, 09, whole day lecture and live demonstration) (Presenter: Dr. Syngcuk Kim, U Penn, PA).

7. Initiator and organizer of the Endodontic Microsurgery Continuing Education Course held on Feb. 5, 2000 (whole day lecture and live demonstration) (Presenter: Dr. John Stropko, Scottsdale, AZ).

8. Co-organizer, Schilder/Gianelly Symposium, Boston U. Oct 29, 2010. One-day symposium. SCHOLARLY ACTIVITIES

A. EXTRAMURAL SCHOLARLY COMMITMENT American Association of Endodontists Standing Committees:

Research and Scientific Affairs Committee – Member (2004-2006) Responsibilities: Provides advice and expertise for those activities related to research and scientific advances and affairs. The committee meets two times per year to review research grant requests and to review submissions for grad and faculty presentations at the annual session. Regenerative Endodontics Committee – Member (2009- ) Responsibilities: Provides advice and expertise for promoting and regulation of the research and clinical work regarding regenerative endodontics.

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The committee meets via conference calls several times a year and whenever there is a need to meet.

External examiner Temple University and Albert Einstein Med. Center Residency Programs Oral mock board – 2006, 2008

AADR/IADR Pulp Biology and Regeneration Group President (2011) Vice President (2010) Program chair Vice President-elect (2009) Responsibilities: review abstracts President-elect (2010) Responsibilities : Program Chair for the AADR/IADR 2010

B. GRANT REVIEW

Extramural

Grant reviewer, NIH/R01/R21/PA grants, study section, June, 2014 Grant reviewer, NIH/R01/R21 grants, study section, Nov, 2013 Grant reviewer, NYSTEM grants, study section, Oct, 2013 Grant reviewer, NIH/R01/R21/PA grants, study section, June, 2013 Grant reviewer, Research Competitiveness Program at American Association for the

Advancement of Science, Feb, 2013 Grant reviewer, NIH/KO8 grants, study section, July, 2012 Grant reviewer, NIH/R15 grants, study section, Feb, 2012 Grant reviewer, NIH/MTE study section, Oct, 2009 Grant reviewer, NIH/ODCS supplement (revision) grant, July, 2009 Grant reviewer, NIH Challenge Grant (RC1), June, 2009 AAE grant reviewer, October, 2004; March & October 2005; March 2006. Grant reviewer, special emphasis panel, NIDCR/NIH initiative (request for applications –

RFA for Development of in vitro models of human oral mucosa relevant to AIDS and mucosal infections), November, 2004 Intramural

Student grant application, UCLA School of Dentistry, 2002, 2003, 2004 UTCD alumni research grant, 2013.

C. SCIENTIFIC COMMITTEES Pulp Biology and Regeneration Group, IADR/AADR, 2009, Vice President elect Pulp Biology and Regeneration Group, IADR/AADR, 2010, Vice President Regenerative Endodontics Committee, AAE, 2010.

D. RESEARCH COLLABORATION (extramural) 2007-2009

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National Taiwan University, Dr. Min-Huey Chen laboratory. Study of dental stem cells and dental pulp regeneration using a minipig model.

2007-2009 Kaoshiung Medical University, Dr. Chern Lai laboratory. Study of dental stem cells

2006-2009 NIH/NIAMS Intramural Cartilage Biology and Orthopaedics Branch (Dr. Rocky Tuan’s group), working on mesenchymal stem cells and tissue engineering.

2005, NIH/NIDCR Intramural Oral Infection and Immunity Branch (Dr. Sharon Wahl’s

group), working on Laser Capture Microscopy and Affymetrix GeneChip. 4/18/06—4/19/06, Harvard University Dr. David Moooney’s lab of Cell and Tissue

Engineering, observing manufacture of PLG scaffolds. INVENTIONS

1. Dental stem cell derived iPS cells (Invention report, Columbia U, 2009) 2. Antimicrobial assay: In vivo simulation system (Invention Report filed-UCLA, 2002) 3. Pulpal tissue regeneration (Invention Report filed-UCLA, 2002). 4. Anti-tumor agents-- in preparation (not active) 5. Endodontic files—in preparation (not active)

PATIENT CARE--FACULTY GROUP PRACTICE

Limited to Endodontics (1995-2004, UCLA) Time commitment: Year round, 2-3 half days/week Responsibility: Treat private patients mostly referred from other UCLA faculty. This is a required duty as a clinical faculty.

Limited to Endodontics (2005-, U Maryland) Time commitment: Year round, one half day/week

OTHER FUNDING HISTORY 1. Recipient of Electric Motor Grant Program from Dentsply (Tulsa Dental). Total of 19 motors and contra angles (worth of $40,000) for both Resident Program and Undergraduate Program at UCLA. April, 2000 GIFTS 1. Global Surgical Corp., $2,000 to sponsor CE course presented by Dr. John Stropko, Feb. 5, 2000 at UCLA.

OTHER SCHOLASTIC ACTIVITIES AND COMMUNITY SERVICES Dec 2010 Invited to write recommendation letter to Dr. Qiang Zhu for his promotion to Professor at University of Connecticut Health Center School of Dental Medicine 8/21-22/10 Endodontic Chair workshop, AAE, Chicago, IL Oct, 2009/2010 BU Endodontic Alumni Fall meetings.

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8/2/02 Meet with the program directors from University of Loma Linda, University of Southern California, and Veteran’s Administration Hospital at Long Beach to discuss program curricula and activities.

2001, 2004 ADA (AAE) Program Directors Workshop. Chicago, IL. 10-16-00 Served as the study subject for the graduate student Megan Abbott-

Moore (University of Oregon Dept. of Anthropology) in her master’s degree project.

8/19-8/20/00 ADA (AAE) Program Directors meeting on accreditation. Chicago, IL. 5/5/00-5/11/00 Accompanying Dr. No-Hee Park, Dean of UCLA School of Dentistry, to

visit Taipei Medical Collage for exchange of dental education experience. 5/4/00 Interviewed by TV station KCBS (California local CBS) for demonstrating

the use of a newly developed endodontic equipment “microfiberoptic endoscope” manufactured by Fiberdent with Dr. James Buhcall at UCLA.

2000, 2003 Attending Dr. Garry Carr’s seminar on Endodontic Microscope in retreatment. Pacific Endodontic Research Foundation, San Diego, CA

11/9/99 Visiting and exchanging education experience with Dr. Lin-Hong Lin, Head of Endodontics, Dental Department, Taipei Medical College Hospital, Taipei, Taiwan, ROC

9/30/99-10/2/99 Dentsply/Tulsa Endodontic Educator Symposium. Dallas, Texas. 6/30/98 Visiting Paris University Dental School. Exchanged education experience

with Dr. Machtou, Paris, France 6/10/98 Received certificate of appreciation presented by Dr. Thomas Serene for

“Outstanding Contribution to Endodontic Research and Teaching” (UCLA). 1/8/98 Visiting and exchanging education experience with Dr. Chun-Pin Lin (DDS,

MS, PhD), Chairman of Endodontics, National Taiwan University, School of Dentistry, Taipei, Taiwan, ROC

1/6/98 Visiting and exchanging education experience with Dr. Ching-Liang Meng (DDS, DMSc), Executive Dean, National Defense Medical Center, Taipei, Taiwan, ROC

12/31/97 Visiting and exchanging education experience with Dr. Chi-Cheng Tsai (DMD, PhD), Director of Graduate Institute of Dental Sciences and Dean of Kaushung Medical College, Kaohsiung, Taiwan, ROC

FUNDRAISE 1. Initiate fundraising to establish Fund of Endodontic for the Division of Endodontics at Columbia University (2009) 2. Constant fundraising to BU endo alumni to maintain Endodontic Alumni Funds. I understand that misrepresentation of academic credentials is a Class A misdemeanor in Tennessee. Therefore by my signature, I attest that the information contained in this document is accurate and correct to the best of my knowledge.

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Signature