HPV Workgroup Update

Chapel Hill

October 20, 2010

Jennifer Allen, Roshan Bastani, Vicky Taylor

Background

• The CPCRN started discussing opportunities for HPV research after FDA approval of the HPV vaccine in 2006

• The HPV Vaccine Workgroup was officially formed after the 2007 CPCRN annual meeting in Boston

• Collaborative HPV vaccine projects were initiated during the second half of the last CPCRN funding cycle

ASPO Presentation

• Participated in a HPV vaccine panel discussion at ASPO (Washington DC, 2008)

• Jennifer Allen, Maria Fernandez, Matthew Kreuter

• Presentation generated a review article

• Fernandez ME, Allen JD, Mistry R, Kahn JA. Integrating clinical, community, and policy perspectives on humanpapilloma virus vaccination. Annual Review of Public Health 2010; 31:235-252.

Survey Measures Project

• Harvard University, Boston

• University of Washington, Seattle

• University of North Carolina, Chapel Hill

• University of California, Los Angeles

• Emory University, Atlanta

• University of Texas, Houston

• Morehouse College, Atlanta

• Centers for Disease Control and Prevention

Survey Measures Project

• Conducted a systematic review of measures of HPV and HPV-vaccine knowledge, attitudes, beliefs, and acceptability

• Allen JD, Coronado GD, Williams RS, Glenn B, Escoffery C, Fernandez M, Tuff RA, Wilson KM, Mullen PM. A systematic review of measures used in studies of human papillomavirus (HPV) vaccine acceptability. Vaccine 2010; 20:4027-4037.

Cognitive Testing Project

• University of North Carolina, Chapel Hill

• University of Washington, Seattle

• Washington University, St. Louis

• University of Texas, Houston

• University of California, Los Angeles

• Harvard University, Boston

• Centers for Disease Control and Prevention

Cognitive Testing Project

• Developed 21 HPV vaccine survey items to assess constructs commonly used in health behavior research, and cognitively tested the items during 62 qualitative interviews with parents of girls in the 9–17 age group

• Richman AR, Coronado GD, Arnold LD, Fernandez ME, Glenn BA, Allen JD, Wilson KM, Brewer NT. Cognitive testing of HPV vaccine survey items for parents of adolescent girls. Under review.

• To be presented at the 2010 APHA annual meeting in Denver

Latino Survey

• University of California, Los Angeles

• University of Texas, Houston

• University of Washington, Seattle

Latino Survey

• Used the Health Behavior Framework to develop a set of 24 core HPV vaccine survey items

• Surveyed Latino parents of girls ages 9–18 in Houston (N=83), Los Angeles (N=274), and Seattle (N=90)

• Data collection is complete and data analysis is ongoing

• In process of determining how best to combine all three surveys into a single manuscript

Latino Survey Los

AngelesSeattl

eHouston 211

Houston Lower Rio

Grande Valley

n=274 n=90 n=39 n=44

Awareness:Heard of HPV vaccine

63% 73% 69% 57%

Receipt:Initiated HPV Vaccine (received ≥ 1 dose)

29% 37% 31% 25%

Acceptability/Willingness:Agree daughter getting the HPV vaccine would be a good idea

64% 81% 64% 93%

n=79 n=90 n=39 n=44

Attitudes/Barriers:Agree daughter getting the HPV vaccine would cause her to have more sex

11% 60% 23% 16%

Attitudes/Barriers:Agree if daughter gets HPV vaccine it may cause health problems in the future

11% 31% 15% 9%

Policy Initiative

• University of California, Los Angeles

• University of Texas, Houston

• University of Washington, Seattle

• University of North Carolina, Chapel Hill

• Harvard University, Boston

Policy Initiative

• Compiled a database of state legislative bills regarding HPV vaccination from January 2006 to June 2008 that contains information on bill origination (date, authors, committee, etc), content, and status

• Laugesen MJ, Carameli K, Mistry R, Needleman J, Taylor V, Ribisl K, Bastani R. All Over the Map: State Legislation on Human Papillomavirus Vaccine (HPV). In progress.

• The manuscript describes and categorizes the range of proposed state legislative bills and their outcomes for the 50 states and the District of Columbia

 

Possible Future Directions

• Cognitive testing of HPV vaccine survey items in other languages

• HPV vaccine surveys in other geographic areas and racial/ethnic groups

• HPV vaccine intervention evaluation research

• Dissemination research addressing evidence-based interventions for promoting vaccine use

• Studies assessing the impact of HPV vaccine legislation on vaccine uptake

• Projects addressing HPV testing

• Incorporation of HPV content into FQHC project