how to convince successful financiers to give you millions of dollars in a project doomed to fail!

75
hey buddy, can you spare a $100 million? how to convince successful financiers to give you millions of dollars in a project doomed to fail! or Michael Polonsky October 7th,

description

hey buddy, can you spare a $100 million? By Mike Polonsky, Oct 7, 2008. Part of the Post Doctoral Fellowship Networking Event.

Transcript of how to convince successful financiers to give you millions of dollars in a project doomed to fail!

Page 1: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

hey buddy, can you spare a $100 million?

how to convince successful financiers to give you

millions of dollars in a project doomed to fail!

or

Michael PolonskyOctober 7th, 2008

Page 2: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

I love love loveentrepreneurs innovation canada

Page 3: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

General Petraeus on powerpoint

"It's how you communicate big ideas - to communicate them effectively."

Page 4: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

what is a presentation

?

Page 5: how to convince successful financiers to give you millions of dollars in a project doomed to fail!
Page 6: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

general specific

Page 7: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

The closet cousin to a power point slide is a billboard!

Page 8: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

350 employees

75 key accounts

Business plan

Momentum

Overcome obstacles

95,000 square feet

8 products

Competitive advantages

Mission

Vision

Values

logo

Track record

Chief financial officer

Strengths

Opportunities

Expert board

Awards

Growth strategy

Organizational chart

Money in the bank

Features and benefits

VC shareholders

Website

Audited statements

Something big coming

Media coverage

Revenue model

Acquisitions

Nice boardroom

Technology

Intellectual property

7 years of hard won memories

But you’ve got a lot to say …

Page 9: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

leave an impression

Page 10: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

On June 4 1940, Winston Churchill delivered a 45 minute speech, commonly known as “We shall fight on the beaches”, to the House of Commons of the British Parliament. It was a great inspiration to an embattled United Kingdom as it entered what was probably the most vulnerable phase of the entire war. Public opinion for the war effort was waning in the face of devastating losses and a formidable enemy.Churchill encouraged a country to keep fighting in 45 minutes.

how do you encourage someone to give you $10M in

45 minutes?

Page 11: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

general specific

Page 12: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

keep it high level don’t DROWN in DETAILkeep it clean

tip (not rule) no. 1

Page 13: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

what is a presentation

?

Page 14: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

350 employees

75 key accounts

Business plan

Momentum

Overcome obstacles

95,000 square feet

8 products

Competitive advantages

Mission

Vision

Values

logo

Track record

Chief financial officer

Strengths

Opportunities

Expert board

Awards

Growth strategy

Organizational chart

Money in the bank

Features and benefits

VC shareholders

Website

Audited statements

Something big coming

Media coverage

Revenue model

Acquisitions

Nice boardroom

Technology

Intellectual property

7 years of hard won memories

You got 45 minutes: on you mark, get set, go …

Page 15: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

You actually only get 23 minutes.

Page 16: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

Marathon 100 metres

Page 17: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

NOW!

huh aha

(rapid transfer)

Page 18: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

are created equal

NOT all

points

Page 19: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

All points are equal

• Interesting point but not really relevant

• Uninteresting point but relevant

• Major, earth shattering, earth quaking point

• Interesting corollary perspective

• Necessary background point

• Interesting-but-dude-is-now-sleeping point

• Because-I-love-the-sound-of-my-voice point

Page 20: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

The point

Big big big support

additional support

additional support

additional support

Page 21: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

The point

Big big big support

additional support

additional support

Underlying takeaway message

Page 22: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

The point

A

Underlying takeaway message

B C

Page 23: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

The point

A

Underlying takeaway message

B C

1 2 3

Page 24: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

24

13/ of all newproducts

The future of medicine

24

Page 25: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

25

Outlook:

Revenue growth of 10 to15 percentin fiscal 2008

Page 26: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

Cangene is fully integrated

Develop from concept to commercialization Manufacture process sensitive biopharmaceuticals Sellniche marketing team for biodefense products and commercial partnerships

Page 27: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

27Strong preclinical franchise

Top 10Preclinical CRO worldwide

400+Active clients

90%Retention rate

8 of 10Largest pharma as clients

A fast growing, highly profitable CRO

27

Page 28: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

28MERCATOR MINERALS LTD.

Strengthens steel

Anti-corrosive agent

Chemical catalyst

Molybdenum

annual market12$ B

*

*Add note here

Page 29: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

GRID it to GREATthink about emphasisthink about scalethink about priorities

tip (not rule) no. 2

Page 30: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

Not words

mapspicturesdiagramsillustrations

Page 31: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

what is a presentation

?

Page 32: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

20-30 slides

• afj;psldk• aslkdflfk• asljkfhf

• afj;psldk• aslkdflfk• asljkfhf

• afj;psldk• aslkdflfk• asljkfhf

• afj;psldk• aslkdflfk• asljkfhf

• afj;psldk• aslkdflfk• asljkfhf

• afj;psldk• aslkdflfk• asljkfhf

• afj;psldk• aslkdflfk• asljkfhf

• afj;psldk• aslkdflfk• asljkfhf

• afj;psldk• aslkdflfk• asljkfhf

• afj;psldk• aslkdflfk• asljkfhf

• afj;psldk• aslkdflfk• asljkfhf

• afj;psldk• aslkdflfk• asljkfhf

• afj;psldk• aslkdflfk• asljkfhf

• afj;psldk• aslkdflfk• asljkfhf

• afj;psldk• aslkdflfk• asljkfhf

• afj;psldk• aslkdflfk• asljkfhf

• afj;psldk• aslkdflfk• asljkfhf

• afj;psldk• aslkdflfk• asljkfhf

• afj;psldk• aslkdflfk• asljkfhf

• afj;psldk• aslkdflfk• asljkfhf

• afj;psldk• aslkdflfk• asljkfhf

• afj;psldk• aslkdflfk• asljkfhf

• afj;psldk• aslkdflfk• asljkfhf

• afj;psldk• aslkdflfk• asljkfhf

• afj;psldk• aslkdflfk• asljkfhf

• afj;psldk• aslkdflfk• asljkfhf

• afj;psldk• aslkdflfk• asljkfhf

• afj;psldk• aslkdflfk• asljkfhf

• afj;psldk• aslkdflfk• asljkfhf

• afj;psldk• aslkdflfk• asljkfhf

Page 33: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

the great ones are more than a series of slides

Page 34: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

power of a narrative

Page 35: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

what is a presentation

?

story1

Page 36: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

which came first?

Page 37: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

hungerno hunger … no plot … no one cares

Page 38: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

Coronary Heart Disease

oneNumber

killer!20%of all deaths

Page 39: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

B R E A K I N G T H R O U G H

Wet AMD

Page 40: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

Meeting the Emerging Exploding DemandInsulin

Page 41: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

What if there wasn’t enough insulin?

Page 42: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

There isn’t.

What if there wasn’t enough insulin?

Page 43: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

43

50% of potential wind energy is lost

0

43

25 - 30%Actual

efficiency

59.3%Maximum

theoretical efficiency (Betz limit)

Page 44: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

4444

Actual misalignment in operationOptimal alignment

LOSTEFFICIENCY

wind

Yaw

Because the wind is always shifting, turbines are almost always misaligned…

ener

gy p

rodu

ced

ener

gy p

rodu

ced

Page 45: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

45

Actual mis-pitch in operation

LOST ENERGY

Optimal pitch

ener

gy p

rodu

ced

ener

gy p

rodu

ced

MORE ENERGYCAPTURED

LOSTEFFICIENCY

…and because the wind is always gusting, the blades are almost always mis-pitched

45

Page 46: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

value proposition

Solution to hunger

Page 47: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

Neuradiab Survival Data

Clinically compelling difference

42%

1980 to

2004

2005

91Surgery + Radiation + Temozolomide + Neuradiab

Surgery + Radiation + Temozolomide

Surgery + Radiation

Survival in weeks

75604515 30 105900

weeks

47

64weeks

53weeks

Page 48: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

CRD5 Rapidly Increases HDL

Crestor(Statin)

Niacin - ERCRD5Poorly toleratedLow market share

Levels still rising Non-optimized formulationHealthy volunteers

% in

crea

se in

HD

L

Page 49: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

Expanding Clinical Benefit

30

(Source: OGY 07)

No drugs approved

Surgerychemo

OvaRex® MAb extends time to relapse

13months

Watchful waitingFrontline

TumorBurde

nCA 125 Level

Months 0 6 16

OvaRex MAb

Relapsediagnosed

10

Initiate OvaRex® MAb therapy

Page 50: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

complete responses

25%

four doses of Proxinium™ complete tumor response

complete responses

Page 51: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

51

FunctionFIRST™ yields results

500A pipeline of

antibodies

lead candidatesFive

51

Page 52: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

52

We can make wind energyproduction more efficient!

Improvement with our technology!

Possibleefficiency

Actualefficiency

0

52

Page 53: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

greed

you have to show them the 10 bagger - Michael Denny

no one invests in hyper growth stories to double their money

Page 54: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

54

25%

market share

if at $5,000 = $692,500,000

ISA247 Psoriasis Opportunity

patients treated with oral immunosuppressants

in the U.S.

per treatment cycle

if at $10,000 = $1,385,000,000per treatment cycle

Establishedsafety and efficacy

Source: Datamonitor54

554,000

ISA247:

Page 55: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

Top 3 drug categories

$ 1billion+

Cytostactics(Cancer)

Antiulcerants(GI tract)

Cholesterol & triglyceride

reducers

World’s Largest Drug Market

5 drugs over

$23.8B

$25.5B

$30.2B

Page 56: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

56

Our potential

$11Billion

Wind turbine opportunity

Yaw benefit

Reduced wear

Improved speed control

Reduced downtime

Expanded operating envelope

Met tower replacement

Airports

Yacht/sailboats

Forest fire fighting

National wind map

+56

Pitch benefit

Page 57: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

$8BSpent annually in North America expanding & replacing current infrastructure

57Resin Systems

Page 58: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

need expressed: hunger

need addressed: value proposition

market opportunity: greed

Page 59: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

don’t come up flatthink about structure

tip (not rule) no. 3

Page 60: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

Not blind faith

brevitypatternsstoriesemotion

Page 61: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

Complexity/quantity Time constraints Durable goals

right information rapidly transferred High impact/recall

don’t drown in detail grid it to great don’t come up flat

Page 62: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

right informationthe

rapidly transferred

high recallwith

messagesdistilled

diagramspictures

everythingnot

maps

illustrations wordsnot

storiespatternsbrevity

emotion blind faithnot

Page 63: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

don’t forget

milestones

request for cash

current shareholders

financings to date

IP

Page 64: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

Milestones

Q3 2005 Q4 2005 Q1 2006

X

X

X

X

X

X

U.S. sales partner

Installed in 25 U.S. hospitalsInitiate studies for expanded indications

Initiate North American multi-centre trial

Initiate combo trial with multi-national partner

File for Canadian and European approval

SPY System

OPTTX System

Page 65: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

Exendin-4 Albumin Conjugate: Next Steps

(PC-DAC™:Exendin-4)

One month multi-dose Phase I/II trial

Page 66: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

Investment Opportunity

– Launching commercial platform

– Expanding content partnerships

– Developing molecular tests

– Scaling quality manufacturing

Seeking

in financing to drive the business forward

$ million51

Page 67: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

recommended reading

made to stick

brain rules

Page 68: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

closing thoughts

Page 69: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

evidence evidence evidence

Page 70: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

show alittle leg …

speed dating

… move on

Page 71: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

…transacts!

generatingearnedattributes

TALKlike a person

be authentic!

STOPthe bullshit

Page 72: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

how do you get to Carnegie Hall?

Page 73: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

100%of zero is zero

dilution

Think

big!!!

Page 74: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

hard work

digging deep

doing better

tip (not rule) no. 4

wimps/settlers need not apply

Page 75: how to convince successful financiers to give you millions of dollars in a project doomed to fail!

thank you