Hormonal Control of Hormonal Control of DigestionDigestion

Gastrin = hormone produced by stomach.

Gastrin +Gastrin +

• Triggered by entry of food into the stomach, and the stretching of the stomach

Gastrin

Gastrin +Gastrin +

Gastrin

Gastrin +Gastrin +

• Promotes the release of HCl &, stomach churning

Cross section of the stomach

these are the folds

Cross section of the stomach

these are the folds

Cross section of the stomach

these are the folds

Cross section of the stomach

these are the folds

Secretin = hormone produced in cells of the small

intestine• Triggered by HCl

acid in the chyme• enters bloodstream

and stimulates pancreatic cells.

• Response = Output of sodium bicarbonate buffer.

• ALSO, stimulates the liver to produce bile

• BILE = emulsifies FAT

Secretin = hormone produced in cells of the small

intestine

First hormone discovered

• Triggered by partially digested protein & fat that

enters the sm. intestine

CCK = hormone produced in cells of the small

intestine

CCK

CCK

• Stimulates Gallbladder contraction to release bile

• Stimulates Pancreas to release enzymes

• Reduces appetite

CCK = hormone produced in cells of the small

intestine

Enterogastrone

• Hormone produced in small

intestine• Triggered by acid - rich chyme filled with

lipids.• Target cells in the stomach and blocks

gastrin• Slows digestion b/c

digestion of fats takes more time

Entero-Entero-gastrone -gastrone -

Enterogastrone

Entero-Entero-gastrone -gastrone -

• Inhibits peristalsis and acid secretion of the stomach

• Slows digestion in the stomach.