Hong Kongthinkasiathinkhk.com/uk/download/synopsis/biotech/albert_yu.pdf · • Clinical research...
Transcript of Hong Kongthinkasiathinkhk.com/uk/download/synopsis/biotech/albert_yu.pdf · • Clinical research...
BioTech at Science Park
www.HKBIO.org.hk
Your Safe and Fast Track to China
Think Asia, think Hong Kong - London 13-09-2011
Albert Cheung Hoi Yu, Ph.D.Albert Cheung Hoi Yu, Ph.D.PresidentHong Kong Biotechnology Organization (HKBIO)
ProfessorInstitute of Systems Biomedicine, Peking UniversityInfectious Disease Center, Peking University
Professor and Vice-directorNeuroscience Research Institute, Peking University
Chairman and CEOHai Kang Life Corporation LimitedBeijing Hai Kang Biotechnology Service Limited
Hong Kong –Poised to be the Asia’s Biotechnology Hub
FOSTERING INNOVATION, SCIENCE and TECHNOLOGY
HighHigh--tech industries are increasingly developing into pillar tech industries are increasingly developing into pillar industries of the global economyindustries of the global economy
For Hong Kong, biotechnology is emerging as For Hong Kong, biotechnology is emerging as the powerhouse engine of science and the powerhouse engine of science and
innovation paving the way for economic innovation paving the way for economic growthgrowth
Biotechnology in Hong KongOVERVIEW
• Recognized by Government as a key growth driver and source of innovation • Close to 300 biotech-related companies doing business in the following
markets:– Healthcare– Chinese medicine– Medicinal devices– Diagnostics
• Approximately 70 companies listed in Hong Kong Stock Exchange and Growth Enterprise Market
• Biotechnology and pharmaceutical industries are highly internationalized, occupy little land, product sizes are generally small, hence Hong Kong conditions suitable for industry and growth.
Source: Innovation and Technology Commission
Biotechnology in Hong KongSOLID R&D SUPPORT
• Among 9 tertiary institutions, 6 heavily engaged in biotechnology-related research
• Over 250 high-impact biomedical papers published annually
• Hong Kong’s two medical schools are ranked best in world of clinical medicine
• Increasing Government support for promotion and advancement of Hong Kong’s Innovation and Technology
• HK Government established Innovation and Technology Commission in 1999 to spearhead Hong Kong towards a world-class, knowledge-based economy. ITC has financed more than 150 biotechnology-related projects since its establishment.
Source: Innovation and Technology Commission
Biotechnology in Hong KongPERFORMANCE AND RECOGNITION
• International recognition in infectious diseases (identification of SARS, Avian Influenza, A/H1N1)
• Genetically modified organisms• Application of molecular testing to food safety • Advance research in anti-cancer herbs• Achievements in quality control and GMP of Chinese
materia medica herbs• Molecular approaches to neuroscience research • Innovative drug delivery technology• Clinical research and biopharmaceuticals accelerating• Recognition for protection of IP rights• Competitive edge in affiliated technology industries
including communication, environmental, nanotechnology and opto-electronics…
…..more
TRENDS AND OPPORTUNITIESMAINLAND CHINA
• In China, biotechnology industry is concentrated in economically developed regions with prestigious tertiary institutions in Beijing, Guangdong, Shanghai. Jiangsu, Zhejiang and Shangdong
• Guangdong ranks front in China’s manufacturing of Western and Chinese medicine
• China has made impressive progress in the last two decades building biotechnology industry, however, there remains a lot of challenges and opportunities ahead to succeed in global market given China’s accession into WTO.
• Factors important for China’s development of biotechnology includes:– Technology, clinical trials– Capital market and exit channel with regards to venture capital– Regulatory and intellectual property issues– Human resource and management
Hong Kong is increasingly an attractive place for Mainland to establish biotechnology business
• China government recognizes Hong Kong as a bridge to the world
• Mainland and Hong Kong Science and Technology Co-operation Committee - established in 2004 by Ministry of Science and Technology and Hong Kong Special Administrative Region
– Guangdong / Hong Kong Technology Cooperation Funding Scheme– Shenzhen / Hong Kong Innovation Circle
• 12 State key laboratories located in Hong Kong
• Focus of China’s 11th 5-year plan and the 12th 5-year plan from 2011-2015
Technology Co-operation with Mainland China
Biochip PlayersHigh density glass slide-based microarray for research market
Microarray platform for research markets; distributors for AFFYMETRIX in China
None of them can even try on routine diagnostic
marketElectric current-based system chip biochip system ; closed down in 2009
No successful commericalizatoin of the biochip system; business closed down
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A New Paradigm A New Paradigm Going to Revolutionize Going to Revolutionize Clinical Clinical DiagnosisDiagnosis
1111
HKLife HKLife EFADchipEFADchip®® TechnologyTechnologyA key differentiator of EFADchip ® is therapid hybridization achieved through proprietary patented technologyOur technology avoids undesirable electrochemical reactions and instabilities happened in other electric current driven chip processesMultiplex detection of various targets (diseases) withScalable, cost effective and established manufacturing processesWorldwide patent portfolio
Electric Field Assisted Diagnostic chipEFADchip®
EFADchip® WaferEFADchip® Automation
SystemEFADchip® Analyzer
EFADchip® Spotter
EFADchip® Cartridge
HKLife Technology Innovation- EFADchipEFADchip®® system
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HKLife Technology Innovation- EFADchipEFADchip®® system
Molecular Biology
Material Science
Optics
Microelectronics
Bioinformatics
Precision Engineering
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Hong Kong Has –World-Class Infrastructure Support
ASTRI
HKPC
HKJCICM
HKSTPC
1. HKIB
forBiotechnology DevelopmentHong Kong
HKIB
BRI
Hong Kong Science and Technology Parks CorporationHong Kong Applied Science and Technology Research Institute Company LimitedHong Kong Jockey Club Institute of Chinese MedicineHong Kong Productivity CouncilHong Kong Institute of Biotechnology LimitedBiotechnology Research Institute…and R&D Centres
Beijing R&D CenterHong Kong Laboratory
EFADchip® PatentGranted – 30 enforceable patents
Apparatus and Methods for Detecting DNA in Biological SamplesHK 1082771A Novel DNA Chips System and Its ManufactureChina ZL01140901.0Method of Electrical Hybridization on DNA ChipsUS 7,390,622, US 7,888,109Malaysia MY-139466-A, China ZL200480030204.4Russia 2359038, Mexico 278420Apparatus and Methods for Detecting DNA in Biological SamplesUS 7,153,687, US 7,749,705, Australia 2003257367Europe 1552017Validated in: Turkey, Belgium, Switzerland, Spain, Greece, Ireland, Monaco, Sweden, Italy, Germany, France, UK, Luxembourg, Netherlands, Denmark, Finland, PortugalSingapore 109848Improvement on DNA ChipsChina ZL02282083.3
All owned by HKLife, a Chinese Company
EFADchip® PatentFiled – 42 pending, 1 proceeding to grant ……
A Novel DNA Chips System and Its ManufactureHK 03107220.4Method of Electrical Hybridization on DNA ChipsHK 07104363.4US 12/113,392Malaysia PI20083009Taiwan 93131325Thailand 094535Australia 2004282235Brazil PI 0.415.342.1Canada 2542518China 200480030204.4Europe 04789841.6India 1762/DELNP/2006Japan 2006-534560South Korea 2006-7007193Singapore 200602227-1Singapore 20087795.0
Apparatus and Methods for Detecting DNA in Biological SamplesUS 12/786,178Australia 2003257367Australia 2007224397Brazil PI 0313409-1Canada 2495520China 03819478.3India 572/DELNP/2005India 5498/DELNP/2007Japan 2004-526591South Korea 2005-7002443Singapore 200700913-7 (Proceeding to grant)Thailand 094535Detection of AnalytesUS 61/195,764UK 0821126.0Taiwan 98128515Thailand 0901004280Etc.
All owned by HKLife, a Chinese Company
Hong Kong serves as link to China in BiotechHong Kong is the Chinese city most exposed to the WORLD
Good example for rule of law, free flow of information and human rights
Strong market economy
China looks to Hong Kong for international experience
Pearl River Delta/Southern China:– 65,000 Hong Kong companies provide employment to over 11 million mainland Chinese
Half of China’s foreign investment comes from Hong Kong
Mainland is Hong Kong’s largest trading partner
CEPA: first free trade agreement between HK and CHINACloser Economic Partnership Agreement
HK BIOTECH NEWSWWW.HKBIO.ORG.HK INNOVATION AND TECHNOLOGY - Since 2009
Healthcare InstituteHospital Health Clinic
Year Total Sanatorium
Total General Hospital
Herbal Hospital
Special Hospital
Country Clinic
Town Clinic
Private Clinique
Community Health Centre
Village Health Room
Woman and
Children Health Centre
Specific Disease Centre
CDCHygiene Control Centre
2005 882206 18703 12982 2620 2682 274 41694 40907 207457 17128 583209 3021 1502 3585 1702
2006 918097 19246 13120 2665 3022 264 40791 39975 212243 22656 609128 3003 1402 3548 2097
2007 912263 19852 13372 2720 3282 237 40679 39876 197083 27069 613855 3051 1365 3585 2553
2008 891480 19712 13119 2688 3437 210 39860 39080 180752 24260 613143 3011 1310 3534 2675
2009 916571 20291 13364 2728 3716 200 39627 38475 182448 27308 632770 3020 1291 3536 2809
2010 936927 20918 13850 2788 4280 204 38836 39175 184848 29308 650749 3025 1274 3513 2913
Source: annual statistics of Chinese Medicine, 2010
Statistics on China Healthcare Institute
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HKLife pioneering success is well recognized by :
Industries local and internationalUniversities and research institutesGovernment leadershipNon-governmental organizationsFood and Public Health AuthoritiesInternational Reference Laboratories
IAFP Executive Director visits HKLife laboratory
Thailand Ministry of Agriculture and Cooperatives Central Lab
United Nation’s FAO Food Safety Officer and Science Director of European Food
Safety Authority (EFSA)
Hong Kong Trade Development Council
Executive Director Mr. Fred Lam
Global Recognition
FOSTERING INNOVATION, SCIENCE and TECHNOLOGYHong Kong –
Poised to be the Asia’s Biotechnology Hub
Think Asia, think Hong Kong - London 13-09-2011