HIV TO SELF-DESTRUCT. MIT RESEARCHWITH TIFFANY AMARIUTA

07/04/2013

A research team at the Biological Engineering Lab at the Massachusetts Institute of Technology (MIT), under the direction of Professor Dr. Essigmann, has dedicated several years to an “out of the box” idea with all its world-class resources.Tiffany Amariuta, 2011 Valedictorian of the Hasbrouck Heights High School, a Bio-Engineering student at MIT, joined this elite research team in November 2011.

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Not even one year later, in August 2012, Tiffany (age 18) was deeply involved with this project performing one-dimensional Fourier Transform Infrared Spectroscopy.

In the process, she observed and identified unexpected spectra that had certain similarities to other typical lethal mutagenesis activators.

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Thus, a molecule that kills the HIV virus was discovered. The molecule 8-oxo-deoxy-guanosine is a nucleoside that acts as an extreme catalyst and may be used in HIV treatment via lethal mutagenis; in other words, whis molecule will increase the rate of reproduction of the HIV virus until the HIV produces enough mutagenic protein and actually destroyes itself.

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Tiffany’s work on the project also included complex geometrical optimizations for tautomerized molecules using Gaussview and UNIX.

 In October 2012, she finished her freshman year at MIT with a 4.8 out of 5.0 GPA, and was approved for another year of Undergraduate Research Opportunity Program

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MIT is consistently ranked as the world’s top engineering university, and offers amazing opportunities. Tiffany has decided to pursue two undergrad-uate degrees, one in Biological Engineering and a second in Physics. Only 2.5 % of MIT’s undergraduate engineering students attempt a double degree.

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The discoveries of the MIT research project and Tiffany’s findings have been submitted for publication in Nature magazine, recognized as the world’s most cited interdisciplinary scientific journal. The article is entitled: “Tautomerism of 8-oxo-2'deoxyguanosine and Its Mutagenicity.”

 Tiffany is the daughter of Mrs. And Dr. Ion Amariuta of Hasbrouck Heights, New Jersey.

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Music: NARCIS IUSTIN IANAU (an 18 years Romanian contra tenor) MAY IT BE LORD OF THE RING

This article was published in “THE GAZETTE” from

USA, in January 13, 2013.

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