History of development History of development of of chemicalchemical pharmacy  pharmacy

industry. industry. 

PPharmacy of soviet time.harmacy of soviet time.

The majority of private The majority of private owners of pharmacies are owners of pharmacies are not pharmacists, and not pharmacists, and persons who have had an persons who have had an opportunity to open stores opportunity to open stores in order to further in order to further personal gain. In cases personal gain. In cases where the pharmacy where the pharmacy owner was not a owner was not a pharmacist, he hired pharmacist, he hired someone to manage the someone to manage the pharmacy of pharmacy of pharmaceutical education. pharmaceutical education. Only one third of the Only one third of the owners of pharmacies owners of pharmacies since the beginning of the since the beginning of the twentieth century were twentieth century were pharmacists.pharmacists.

Fragments of Pharmacy Fragments of Pharmacy Museum in LvivMuseum in Lviv

Pharmacies in the city guided individuals Pharmacies in the city guided individuals with higher pharmaceutical education had with higher pharmaceutical education had premises and equipment, which are more premises and equipment, which are more or less meet the requirements of or less meet the requirements of pharmacy and have the right to set pharmacy and have the right to set apothecary students called "normal".apothecary students called "normal".

Owners of pharmacies, of course not set Owners of pharmacies, of course not set ourselves the task to improve the supply ourselves the task to improve the supply of medicines. Their efforts were directed to of medicines. Their efforts were directed to obtain maximum profit from trafficking in obtain maximum profit from trafficking in drugs and other goods.drugs and other goods.

In September 1909 in Kiev started In September 1909 in Kiev started publishing the magazine "Life pharmacist" publishing the magazine "Life pharmacist" who played in the history of the trade who played in the history of the trade union movement servants pharmacists union movement servants pharmacists that time a significant role.that time a significant role.

Documents that regulate the procedure for Documents that regulate the procedure for opening pharmacies. opening pharmacies.

New Apothecary statute New Apothecary statute in 1836 to allow the in 1836 to allow the opening of pharmacies opening of pharmacies wherever there is a wherever there is a need for this, any need for this, any citizen, but could only citizen, but could only manage a pharmacy manage a pharmacy pharmacist. Permission pharmacist. Permission to open a pharmacy to open a pharmacy medical department medical department issued police. But before issued police. But before that it was necessary to that it was necessary to obtain a written obtain a written response from the response from the owners of the nearby owners of the nearby pharmacies whether to pharmacies whether to open a new pharmacy.open a new pharmacy.

In addition, the 1864 In addition, the 1864 Pharmaceutical Society Pharmaceutical Society was established to was established to promote pharmacy and promote pharmacy and medicine. But, as full medicine. But, as full members of this society members of this society were only were only pharmaceutical pharmaceutical pharmacy owners, they pharmacy owners, they primarily defend their primarily defend their interests and fought interests and fought against the expansion of against the expansion of pharmacy. This led to pharmacy. This led to the situation that the situation that medical care was medical care was extremely poor, and the extremely poor, and the number of private number of private pharmacies - small.pharmacies - small.

Therefore, in 1873 issued Therefore, in 1873 issued rules to eliminate harmful rules to eliminate harmful competition and improve competition and improve medical care for each medical care for each pharmacy establish pharmacy establish standards for public standards for public service and the number service and the number By doing recipes. Thus, By doing recipes. Thus, for metropolitan for metropolitan pharmacies - 12 thousand pharmacies - 12 thousand people and 30 thousand people and 30 thousand prescriptions per year per prescriptions per year per pharmacy for provincial pharmacy for provincial cities - 10 thousand cities - 10 thousand people and 15 thousand people and 15 thousand recipes, etc. For smaller recipes, etc. For smaller settlements set only the settlements set only the distance between distance between pharmacies - at least 15 pharmacies - at least 15 miles.miles.

It is clear that the owners It is clear that the owners of pharmacies resorted of pharmacies resorted to various tricks to hide to various tricks to hide the real number By the real number By doing the pharmacy doing the pharmacy counter (reduced). As a counter (reduced). As a result of these rules result of these rules have been changed have been changed and remained the only and remained the only inhabitants of the rate inhabitants of the rate and the distance and the distance between rural between rural pharmacies was pharmacies was reduced to 7 miles.reduced to 7 miles.

Having received permission to open a Having received permission to open a pharmacy, an entrepreneur had to pharmacy, an entrepreneur had to exercise their right during the year, and exercise their right during the year, and then he lost it. Also forbidden to own or then he lost it. Also forbidden to own or manage simultaneously two pharmacies.manage simultaneously two pharmacies.Before opening a pharmacy subjected to Before opening a pharmacy subjected to inspection inspector drug administration inspection inspector drug administration to identify and provide sufficient range of to identify and provide sufficient range of medicines, equipment, and equipment, medicines, equipment, and equipment, which is necessary for the smooth which is necessary for the smooth functioning.functioning.

In 1905 adopted a new In 1905 adopted a new Apothecary Charter, to Apothecary Charter, to which it was entitled to the which it was entitled to the governors to authorize the governors to authorize the opening of pharmacies. opening of pharmacies. Open pharmacy allowed Open pharmacy allowed any interested person. The any interested person. The owner of the pharmacy owner of the pharmacy could he manage could he manage pharmacy or hiring pharmacy or hiring manager, but in this and in manager, but in this and in the second case, it could the second case, it could be just the person who be just the person who had the title of pharmacist, had the title of pharmacist, aged at least 25 years. aged at least 25 years. The exception to this rule The exception to this rule is allowed only with the is allowed only with the permission of the Minister permission of the Minister of Interior.of Interior.

Order dispensing drugs from Order dispensing drugs from pharmacies.pharmacies.

Medications dispensed by prescription, copies of Medications dispensed by prescription, copies of prescriptions, as well as oral and written prescriptions, as well as oral and written demands individuals (non-prescription).demands individuals (non-prescription).Recipes that have entered the pharmacy Recipes that have entered the pharmacy remained in storage for three years. Besides the remained in storage for three years. Besides the content of each recipe was submitted to the content of each recipe was submitted to the appropriate recipe books indicating the date, appropriate recipe books indicating the date, month, year and number of prescription, name of month, year and number of prescription, name of patient and doctor, method of application and patient and doctor, method of application and amount HAVE pharmacy for medicines amount HAVE pharmacy for medicines manufactured.manufactured.At the request of the patient or doctor pharmacy At the request of the patient or doctor pharmacy was obliged to give a copy of the recipe, which was obliged to give a copy of the recipe, which she kept after manufacture drugs, but a repeat she kept after manufacture drugs, but a repeat dispensing prescription medicines copies held dispensing prescription medicines copies held only when a member of the medicine were potent only when a member of the medicine were potent or poisonous substances.or poisonous substances.

Pharmacy was to have a Pharmacy was to have a list of doctors who list of doctors who resolved medical resolved medical practice. The first practice. The first medical list or calendar medical list or calendar was compiled in 1807. was compiled in 1807. MIA invited to MIA invited to pharmacies lists pharmacies lists physicians, prescription physicians, prescription drugs are dispensed drugs are dispensed and found that the and found that the capital engaged in capital engaged in medical practice many medical practice many people who had no people who had no medical training (there medical training (there were about 200 were about 200 doctors and 380 doctors and 380 discharged recipes).discharged recipes).

According Apothekarian According Apothekarian Charter in 1836 Charter in 1836 without prescriptions without prescriptions allowed to release only allowed to release only drugs that did not drugs that did not belong to the group of belong to the group of toxic and potent.toxic and potent.Poisonous medicines Poisonous medicines allowed to release allowed to release without prescription without prescription artists, artisans, artists, artisans, workers in factories, as workers in factories, as a lot of this kind of find a lot of this kind of find use in the manufacture use in the manufacture of paints, as well as in of paints, as well as in other industries.other industries.

The pharmacy is not The pharmacy is not permitted the sale of permitted the sale of alcoholic beverages, as well alcoholic beverages, as well as "any kind of covert as "any kind of covert medication", except medication", except approved Medical Council, approved Medical Council, in which case the in which case the composition of the "secret composition of the "secret tool" pharmacy must keep tool" pharmacy must keep secret until the expiration secret until the expiration privilege. According privilege. According Aptekarskii Charter in 1836 Aptekarskii Charter in 1836 to prepare medicines in the to prepare medicines in the pharmacy had the right pharmacy had the right holder or pharmacy holder or pharmacy manager. In the case of manager. In the case of their absence - assistant their absence - assistant pharmacist. Pharmacy pharmacist. Pharmacy functioned round day, functioned round day, because at night it always because at night it always had to be a pharmacist.had to be a pharmacist.

In 1837 in order to regulate dispensing drugs from In 1837 in order to regulate dispensing drugs from pharmacies was issued on the distinction of pharmacies was issued on the distinction of external medicines from internal. The order was external medicines from internal. The order was required to external medication, regardless of required to external medication, regardless of designation method Doctors had signature yellow designation method Doctors had signature yellow color and that, in general, all signatures are not color and that, in general, all signatures are not tied, and prykleyuvalysya to packaging. This was tied, and prykleyuvalysya to packaging. This was due to the fact that cases of poisoning, when due to the fact that cases of poisoning, when instead of taking medicine solution for outdoor instead of taking medicine solution for outdoor use.use.Resolution and application to pharmacy Charter Resolution and application to pharmacy Charter constantly renewed. Legislative activity in the constantly renewed. Legislative activity in the pharmaceutical industry engaged experts who pharmaceutical industry engaged experts who had no pharmaceutical education, mainly doctors had no pharmaceutical education, mainly doctors and lawyers. Only in 1830, when the Medical and lawyers. Only in 1830, when the Medical Council introduced two posts of deputies from Council introduced two posts of deputies from pharmaceutical Society.pharmaceutical Society.

History of chemical and pharmaceutical History of chemical and pharmaceutical industryindustry

In 1918 signed a decree on In 1918 signed a decree on the nationalization of the nationalization of pharmacies. Prior to July pharmacies. Prior to July 1920 all pharmacies in 1920 all pharmacies in Ukraine were Ukraine were nationalized, passed into nationalized, passed into the hands of the state.the hands of the state.At the end of 1923 was At the end of 1923 was created created Ukrderzhmedtorh, who Ukrderzhmedtorh, who took leadership took leadership hubmedtorhamy and hubmedtorhamy and trade of medicines. The trade of medicines. The same 1923 same 1923 Ukrderzhmedtorh was Ukrderzhmedtorh was renamed in Ukrmedtorh.renamed in Ukrmedtorh.Fragment Pharmacy Museum, Kyiv

At the end of the nineteenth At the end of the nineteenth - early twentieth century - early twentieth century emerging chemical-emerging chemical-pharmaceutical industry in pharmaceutical industry in Galicia. The volume of Galicia. The volume of laboratory works in laboratory works in Galician pharmacies great Galician pharmacies great extent volume increased extent volume increased and became concrete in and became concrete in Nineteenth Century Nineteenth Century through the development through the development of industrial relations in of industrial relations in Galicia, which demanded Galicia, which demanded considerable number of considerable number of chemical substances for chemical substances for technological processes of technological processes of various industries.various industries. Fragment Pharmacy Museum, Kyiv

In the first decade twentieth In the first decade twentieth century firm "Peter century firm "Peter Mikolyash i Union is" Mikolyash i Union is" provided a quarter of total provided a quarter of total needs of the entire mass needs of the entire mass of medicinal Galicia. of medicinal Galicia. V1921 became a legal V1921 became a legal entity - a society of entity - a society of chemical establishments chemical establishments "Laocoon." After the War "Laocoon." After the War (1945 on) - Plant health (1945 on) - Plant health preparations "Laocoon", preparations "Laocoon", 1946 - Lviv chemical-1946 - Lviv chemical-pharmaceutical factory, in pharmaceutical factory, in 1986 JSC "Galichfarm."1986 JSC "Galichfarm."

Peter Mikolyash

In 1916 was In 1916 was published the published the brochure "structure brochure "structure is chemical-is chemical-pharmaceutical pharmaceutical factory" that factory" that contributed contributed unification of unification of technological technological processes already processes already existing and created existing and created enterprises inenterprises in

In Kharkov Polytechnic Institute In Kharkov Polytechnic Institute in under the leadership of in under the leadership of Alexander I. Hunder produced Alexander I. Hunder produced chloroethyl, ammonium chloroethyl, ammonium sulfate, sodium chloride, in the sulfate, sodium chloride, in the University under the leadership University under the leadership of KA Krasuskoho i of KA Krasuskoho i Pyschymuka - salitsylaty c to Pyschymuka - salitsylaty c to Kharkov medical society will - i Kharkov medical society will - i fityn lecithin. At the end of fityn lecithin. At the end of 1916 these combined 1916 these combined production of chemical-production of chemical-pharmaceutical institute.pharmaceutical institute.In Crimea, near Saki Lake in In Crimea, near Saki Lake in 1916 built factory of 1916 built factory of brombenzol, which first started brombenzol, which first started getting bromine. In Odessa getting bromine. In Odessa was created chloroform plant.was created chloroform plant.

Kharkiv Polytechnic   institute

Needs of the population in drugs was Needs of the population in drugs was satisfy only on 11%. The work started in satisfy only on 11%. The work started in refineries Kyiv, Kharkov, Odessa, Lubny. refineries Kyiv, Kharkov, Odessa, Lubny. In 1925 put into operation Kyiv chemical-In 1925 put into operation Kyiv chemical-pharmaceutical factory with name pharmaceutical factory with name M.Lomosonosov - the first enterprise to M.Lomosonosov - the first enterprise to produce synthetic pharmaceuticals, produce synthetic pharmaceuticals, established in the Ukraine - chloroform, established in the Ukraine - chloroform, salitsyl acid, sodium salitsylat.salitsyl acid, sodium salitsylat. Continued development of galenic Continued development of galenic production aptekoupravlinnyah - 28 production aptekoupravlinnyah - 28 factories. In 1931, a new chemical-factories. In 1931, a new chemical-pharmaceutical factory "Red Star"pharmaceutical factory "Red Star"

In 1957 in the Ministry of Health USSR In 1957 in the Ministry of Health USSR was established management was established management pharmaceuticals i medical technique. pharmaceuticals i medical technique. In 1967 he was created Ministry In 1967 he was created Ministry medical industries. Growth products medical industries. Growth products medical industry grew by an average medical industry grew by an average of 47% (10% - WORLD). In 1985 he of 47% (10% - WORLD). In 1985 he was the abolishment of the Ministry was the abolishment of the Ministry medical industries. On the basis of medical industries. On the basis of the Ministry of General the Ministry of General Administration i microbiological Administration i microbiological industries established the Ministry of industries established the Ministry of health i microbiological industries.health i microbiological industries.

The first company The first company produced medicinal produced medicinal preparations, the preparations, the second release of second release of proteins, feed additives, proteins, feed additives, products for animal products for animal husbandry. When husbandry. When obye'yednanni two obye'yednanni two ministries producing ministries producing ready pharmaceuticals ready pharmaceuticals was pushed into the was pushed into the background. Thus, background. Thus, investment in chemical-investment in chemical-pharmaceutical industry pharmaceutical industry accounted for 40%, and accounted for 40%, and microbiological - 60%.microbiological - 60%. Chemical-pharmaceutical

factory by M.Lomosonosov

Lagging in the field of drugs been significant in Lagging in the field of drugs been significant in former Soviet Union. In the disposal of health former Soviet Union. In the disposal of health was a little more than three thousand was a little more than three thousand pharmaceuticals, the State industry was - pharmaceuticals, the State industry was - 40%, imports from the countries of the 40%, imports from the countries of the economic Mutual Assistance (CMEA) - 40%, economic Mutual Assistance (CMEA) - 40%, 10% - produced farmfaceutical factories and 10% - produced farmfaceutical factories and pharmacies near 10% - Persistent deficit. For pharmacies near 10% - Persistent deficit. For comparison, the market medykamentiv U.S. comparison, the market medykamentiv U.S. at that time was represented by 19,000 at that time was represented by 19,000 preparations, Japan - 15093, Switzerland - preparations, Japan - 15093, Switzerland - 9359. Germany - 8930, Ispaniyi - 5830, 9359. Germany - 8930, Ispaniyi - 5830, France - 5255, Italy - 5200.France - 5255, Italy - 5200.

In 1991 he created concern "Ukrmedbioprom." In 1993, In 1991 he created concern "Ukrmedbioprom." In 1993, on its basis - the State Committee for medical and on its basis - the State Committee for medical and microbiological industry in 1998 - uviyshrv Committee microbiological industry in 1998 - uviyshrv Committee of the Ministry of Health of Ukraine. Now for the of the Ministry of Health of Ukraine. Now for the manufacture of medicinal preparations in Ukraine manufacture of medicinal preparations in Ukraine corresponds to the Civil Service og drugs and medical corresponds to the Civil Service og drugs and medical devices. Today the production of medicinal devices. Today the production of medicinal preparations involved in Government, Corporate and preparations involved in Government, Corporate and private enterprise.private enterprise.

By state enterprises belong "Lvivdialik" By state enterprises belong "Lvivdialik" Odessa industrial chemical-Odessa industrial chemical-

pharmaceutical enterprise, Odessa pharmaceutical enterprise, Odessa enterprise producing bacterial drugs, enterprise producing bacterial drugs,

Experiments plant State Scientific Experiments plant State Scientific Center of the pharmaceuticals, Center of the pharmaceuticals,

"Health of the people" and other."Health of the people" and other.      By privatized enterprises belong:       By privatized enterprises belong:

FF "Darnitsa", JSC Farmak ", JSC" FF "Darnitsa", JSC Farmak ", JSC" Galychfarm ", JSC" Kievmedpreparat Galychfarm ", JSC" Kievmedpreparat ", JSC" Lubnypharm "FF" Health "and ", JSC" Lubnypharm "FF" Health "and

other.other.

Pharmaceutical Firm "Darnitsa" was created in 1954 Pharmaceutical Firm "Darnitsa" was created in 1954 In 1994 FF "Darnitsa" was purchased by the In 1994 FF "Darnitsa" was purchased by the workforce. Adopted a program of restructuring workforce. Adopted a program of restructuring that missed changes in almost all functional areas that missed changes in almost all functional areas of firm activity. Since 1994, work began to bring of firm activity. Since 1994, work began to bring the firm activities in conformity with the the firm activities in conformity with the conditions of good manufacturing practice (GMP). conditions of good manufacturing practice (GMP). In 1995 the department was created soft In 1995 the department was created soft medicinal forms. Implemented validation of medicinal forms. Implemented validation of manufacturing processes that allow to control not manufacturing processes that allow to control not only the intermediate products, but also the only the intermediate products, but also the process of production. Taken IMPORTANT steps process of production. Taken IMPORTANT steps recruiters political image. Conducts regular recruiters political image. Conducts regular certification, a system of permanent training of certification, a system of permanent training of staff that crucial seminars, trainings, instructing. staff that crucial seminars, trainings, instructing. Full product range includes more than 90 titles.Full product range includes more than 90 titles.

Pharmaceutical firm Pharmaceutical firm "Darnitsa""Darnitsa"

OJSC «Farmak»

Open Joint-Stock Company "Farmak" was created in 1991 on the basis of the Kyiv chemical-pharmaceutical plant Nat. Lomonosov. It was the first enterprise of the synthesis of pharmaceuticals substantsiy - chloroform, salitsyl acid and other. OJSC "Farmak" is one of the leading places with the production of medicinal preparations and is the basic enterprise of producing radiopaque means. It produces more than 80 products naming different purpose: medical preparations for medical and veterinary practice, chemical substantses and others.

Borschahivskyy CPP is history from 1947, with production artel. Today is one with the largest enterprises in Ukraine manufacturing medicinal preparations. The range of products increased from 14 to 90 names.

JSC "Kievmedpreparat" was launched in 1848 - Steam pharmaceutical laboratory i herbal preparations. In 1908 there - South-Russian trading company bathroom goods. The main producer of medicinal preparations, antibiotics and insh.      Pharmaceutical Firm "Health" is history since 1907 as the company "Halenyka" from 1923 - chemical-pharmaceutical factory "Health of workers." The range of pharmaceuticals is more than 100 items

JSC "Kievmedpreparat"

In 1999, sales volume of medicinal In 1999, sales volume of medicinal preparations for the World Pharmaceutical preparations for the World Pharmaceutical Market increased at 10,7% and reached Market increased at 10,7% and reached 332.2 billion dollars. The share of the 10 332.2 billion dollars. The share of the 10 large HOT LINKS accounted 79% of total large HOT LINKS accounted 79% of total sales volume: USA - 130.1 billion. (39 world sales volume: USA - 130.1 billion. (39 world market), Japan - 53.% Billion (16%), market), Japan - 53.% Billion (16%), Germany - 18.5 (5%), France - 17, 8 (5%), Germany - 18.5 (5%), France - 17, 8 (5%), Italy - 11 (3%), England - 11 (3%), Spain - Italy - 11 (3%), England - 11 (3%), Spain - 6.6, Braziliya - 6.3 China - 6.2 billion (2%), 6.6, Braziliya - 6.3 China - 6.2 billion (2%), Canada - 5.5. Total: 266 800 000 000Canada - 5.5. Total: 266 800 000 000

Thank you for Thank you for your attention.your attention.