High Performance IOL Power Calculation….at the push of a button

OIS, San Diego16th April 2015

Michael Mrochen, CTO and Co Founder

IOL Power CalculationIt takes years of learning and experience!

Google search result on “IOL Power Calculation”

“latest publications”

“previous patient history” “device specific knowledge”

“surgeon specific A-constant”“Keratometer index”“Ultra-sound equivalence”

How to match the best outcomes?NHS Standard

85% within +/- 1D55% within +/- 0.5DRoyal College of Ophthalmic Cataract Surgeons Guidelines, Gale et al, 2006

More recently“With modern optical biometry for the majority of patients, informed formula choice and IOL constant optimisation outcomes of more than 90% within ±1 D and more than 60% within ±0.5 D of target are achievable”.R.Sheard, Optimising Biometry for best outcomes in cataract surgery, Eye, 2014

To achieve these results takes time for every patient and considerable expertise

The Problem

• Historical IOL power formulae are:– Good for the “average” refractive outcome (SEQ)– Poor for predicting the individual refractive outcome

• High complexity driven by variety of formulae available for– Short or long eyes– Astigmatic eyes– Post-refractive surgery eyes

• Improving refractive outcomes based on formulae requires:– Experience– Time to optimize and implement for the individual patient– Reliable historical clinical data for A-constant optimization

Mirricon –A new Ocular Biometer for High Performance IOL Power Calculation

•Results at the push of a button assuring:• Convenience – minimal training time and

improved clinic throughput

•Easy decisions without great expertise and experience delivering:

• Predictable outcomes - Excellent and consistent results every time

• Safety – Reducing the possibility of human error in IOL Power calculation

•One preoperative solution for all types of eyes

Why is Mirricon different?

Physical Optical Testing with Model Eyes

Physical Optical Testing with Model Eyes

First in human useFirst in human use

January 2014

May 2014

May 2015

POC – study in 100 cataract eyes

POC – study in 100 cataract eyes

Status of DevelopmentApril 2014

Device developmentDevice development

Multi Million InvestmentMulti Million Investment

4 patents filed (1 approved)4 patents filed (1 approved)

R&D ProjectR&D Project

2010

What are we looking for?

Partnership opportunities with IOL and Device

companies

Partnership opportunities with IOL and Device

companies

Investment partners to execute our roadmap for commercialization

Investment partners to execute our roadmap for commercialization

Your contactsFounders

Mirricon - High Performance IOL Power Calculation….at the push of a button