Health Impact

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    HEALTH IMPACTS OF

    PARTICULATE MATTER

    PROPOSED METHODOLOGY

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    INTRODUCTION AND BACKGROUND

    The effect of particulate matter in the health of

    the people as the most important impact of airpollution have been identified as the key problem

    as shown from various studies in developedcountries (UNEP, 2007).

    The size of the particles is most important andthe recent studies have identified fine particle

    fraction called PM2.5 (with a mean aerodynamic

    diameter of or smaller than 2.5 microns) as beingespecially harmful because they penetratedeeply, persist in the lungs and may reach thealveolar region. 2

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    Basically, developed countries are concerned

    about outdoor air pollution, as; indoor airpollution is not a major issue in their context.

    Developing countries like Nepal are at doublejeopardy; as the problem of outdoor as well asindoor air pollution is growing fast, and those

    pollutions are interchangeable.

    Numerous studies suggest that PM10 and PM2.5contribute to excess mortality andhospitalizations for the cardiac and respiratorytract disease (McGranahan and Murray, 2002). 3

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    RATIONALE

    Relatively fewer studies are made in the

    developing countries than in developed countries.

    With the increasing pollution, the concentration

    of air pollutants in major cities are higher andthe source and chemical composition of particlesin cities in developed and developing countriesmay differ.

    Consequently information is needed to assess theimpacts of the much higher concentrations of

    PM10 (with a mean aerodynamic diameter of orsmaller than 10 microns) and PM2.5 found in thelarge cities of developing countries. 6

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    As most lung alveoli are formed postnatal,

    changes in the lungs continue throughadolescence and the developing lungs of children

    are more vulnerable to the adverse effects of airpollution than adult lungs.

    Children are more susceptible to the exposure tothe harmful particles than adults because of their

    higher susceptibility to higher ventilation rates,

    higher relative concentrations of particles intosmaller lung volumes and higher levels ofphysical activity.

    The impact of air pollutant and its adverse effect

    may harm child till their adulthood.

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    As child health is an essential indicator for the

    overall assessment of country health status, thisstudy will certainly provide a basis to understand

    the effect of air pollutants on the health of thechildren. This study can address the need for theinformation on the effects of air pollution on

    health in South Asia at the high concentrationcommonly found in large cities in South Asia, and

    provide locally-gathered evidence to supportactions by government to control particulateemissions.

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    NATIONAL STANDARDS - AMBIENT AIR

    Parameter AVG Time Conc., Max.

    TSP 24 hour 230 g/m3

    PM10 24 hour 120 g/m3

    NO2 Annual24 hour

    80 g/m3

    40 g/m3

    SO2 Annual

    24 hour

    70 g/m3

    50 g/m3

    CO 8 hour

    15 minute

    10,000 g/m3

    100,000 g/m3

    Lead Annual 0.5 g/m3

    Benzene Annual 20 g/m3

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    NATIONAL INDOOR AIR QUALITYSTANDARD

    AND IMPLEMENTATION GUIDELINES 2009

    Pollutant Maximum

    concentration

    Averaging

    time

    Particulate Matter(PM10) 120 g/m3 24 hour

    200 g/m3 1 hour

    Particulate Matter(PM2.5) 60 g/m3 24 - hours

    100 g/m3 1 hour

    Carbon Monoxide (CO) 9 ppm (mg/m3) 8 hour

    35 ppm (mg/m3) 1 hour

    Carbon Dioxide (Co2) 1000 ppm (mg/m3) 8 - hours

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    STUDYTOPIC

    Impacts of particulate matter on the respiratory

    health ofSchool Children

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    OBJECTIVES OF THE STUDY

    General Objective

    To assess the impact of air pollution (ParticulateMatter) in respiratory health of school children ofselected school(s) in Kathmandu

    Specific Objective

    To determine whether there is an associationbetween daily PM10 and PM 2.5 concentration andrespiratory health and lung function in children

    To determine the level of relationship of PM andrespiratory health

    To assess the severity of impacts of PM onrespiratory health

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    VARIABLES

    Dependent Variable

    y Respiratory health and lungfunction

    o Independent variables

    Socio-demographic and

    economic variables

    Air pollution related

    variables

    Confounding variables

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    VARIABLES.

    Socio-demographic andeconomic variables Age

    Sex

    Parents education

    Economic status of thefamily

    Air pollution relatedvariables Preventive measures

    taken

    Infrastructure of theschool

    Confounding variables

    Other systemic

    illnesses

    Housing conditions

    Simultaneous

    exposure to other

    pollutants

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    CONCEPTUAL FRAMEWORK

    Sociodemographic& EconomicVariables

    Air Pollution relatedvariables

    Protective Factors Hindering Factors

    RespiratoryHealth/Lung

    Function

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    METHODOLOGY

    Study sign

    y Correlational study a longitudinal study usingquantitative methods

    Study Site

    y Putalisadak (Kathmandu): School near by AQMS

    S

    tudy Durationy 3 months

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    METHODOLOGY. Study Population

    Children of selected schools of age between 9-14 years

    Inclusion Criteria

    Age between 9-14years

    Studying in the school

    at least since 1 year

    School located close to

    the AQMS

    Exclusion Criteria

    Smokers Use of solid fuel at

    home

    Residing more than 3

    km from AQMS

    Child having asthmaor other chronicrespiratory illness

    Child with smoker inthe home

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    SAMPLING

    Sampling technique

    y Purposive selection of schools

    y Proportionate random sampling

    Sampling unit

    y Children of the selected schools within the age limit

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    SAMPLING.

    Sample selection

    y Schools finalized

    y List of students between age 9-14

    y

    Randomly select the required sample (500)y Consider them for the initial baseline survey

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    SAMPLING.

    For the health impact aspect

    y Exclude the subjects as per the exclusion criteria

    y Exclude voluntary exclusions (if any)

    y

    Obtain consent both from the subject as well asparents

    y Finalize the number of participants to undergo theregular study

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    DATACOLLECTION

    Tools

    Structured questionnaire

    Health check up check list

    The questionnaire will be translated into Nepali and the

    language will be kept simple and understandable

    Techniques Self/parental administration of questionnaires

    Completing the check list by the medical

    practitioners21

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    DATACOLLECTION

    Methods

    y Recording the PEFR readings in the standard sheets

    y

    Daily notes of any illness particularly that ofrespiratory health to be noted in a diary provided

    y Diary writing will be supervised by the trainedteachers or technicians/paramedics

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    DATA FROM THE SUBJECTS

    PEFR readings will be collected everyday in the

    school may be at the end of the day

    This process will be continued altogether for 6weeks including days of high and low pollution

    Data of PEFR reading as well as information

    from the questionnaire will be obtained in bothdry as well as wet season

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    PARTICULATE AND WEATHER DATA

    Daily data of PM10 and PM 2.5 as well as that of

    other pollutants if available will be taken.

    Relevant meteorological data such as maximum,minimum and average temperature, relativehumidity and wind speed for the same period willbe obtained from the department of meteorology

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    PRETESTING

    The questionnaires will be pretested in a school

    other than the school to be used for study.

    The school for pretesting will have similarconditions as well as near by the AQMS

    Necessary amendments will be made after this in

    the questionnaires

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    DATAANALYSIS

    Data obtained from these procedure will beentered in Epi Info and then imported in SPSSfor analysis.

    Simple descriptive analysis will be done for thegeneral characteristics of the participants

    To see the correlation of the PM concentration

    with respiratory health regression analysis willbe done

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    LIMITATION OF THE STUDY

    Expected findings may not be generalized due to

    various factors:

    y

    Purposively selected school

    y Limited number of school

    y Possibility of various confounding factors

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    THANK YOU28