Growth and Development 25 Mar 2011
-
Upload
firdaus-aslam -
Category
Documents
-
view
28 -
download
1
Transcript of Growth and Development 25 Mar 2011
Prof. Dr. Quah Ban SengDepartment of Paediatrics
MMMC
Normal Growth and Development in Children
Objectives
• Phases of growth in children
• Common anthropometric measurements
• Pubertal changes
• Developmental milestones
Phases of Growth in Childhood
Years1 2 12Conception Birth
100
85
45
30
% A
dult
Hei
ght
Fetal 30%Uterine environment
Infantile 15%NutritionGood HealthThyroid hormones
Childhood 40%Growth HormoneThyroid HormonesGood HealthGenes
Pubertal 15%Sex HormonesGrowth Hormone
Anthropometric Measurements
• Height
• Weight
• Head Circumference
Measuring Weight
• >36 months weighed standing on scale
• Wearing lightweight clothing
• Recorded to nearest 0.01 kg
• Stands on center of scale platform
• Repositioned & measurement repeated
• Readings agree within 0.1 kg
Weight Gain Infancy & Childhood
• Term neonates: regain birth weight by 10 to 14 days
• Weight gain: – 30 gm/day until 3 months of age
– 20 gm/day 3 and 12 months of age
• Infants – Double birth weight by 4 months of age
– Triple birth weight by 1 year of age
• Children gain 2 kg/year between 2 years and puberty
Weight Charts
Frankfort Horizontal Plane
• Line from most inferior point of orbital margin to left tragion– Tragion: deepest point in
notch superior to tragus of the auricle
• Align Frankfort plane 90° to stadiometer & parallel to headpiece
Height Measurement
Technique
Head, shoulders, buttocks, & heels in contact with vertical surface
Fixed measuring device attached to wall (stadiometer)
Movable head piece 90° to stadiometer
Hat/hair ornaments removedHead in line with head plate Horizontal axis of vision
Apply gentle traction beneath jaw to maintain position
Shoes off; heels together
Measuring Length
• Recumbent Length: <24 months of age or child 2 to 3 yrs (cannot stand unassisted)
• No shoes, no hair ornaments & wearing light underclothing or diaper
• Measure length to nearest 0.1 cm
• Reposition and Repeat measurement
• Both readings agree within 1 cm
Length board with fixed headpiece & moveable footpiece
90° to surface of table
Length/Height Gain
• Average length at birth (term) 50 cm
• 25 cm during 1st year of life
• 10 cm between 12 and 24 months
• 7.5 cm between 24 and 48 months
• Reach ½ adult height by 24 to 30 months
• 4-5 cm/year between age 4 years and puberty
Upper segment/lower segment ratio
Birth 1.7
3 yrs 1.33
5 yrs 1.19
10 yrs 1.0
Lower segment: Top of symphysis pubis to plantar surface of the footUpper segment: Sitting height
Length / Height Charts
Head Circumference• Recorded routinely until 2-3 years old• Measure at end of physical examination• Use a flexible, non-stretchable tape• Encircle head 1 ‒ 2 cm above glabella anteriorly & most
prominent portion of occiput posteriorly (largest circumference)
• Measurement read to nearest 0.1 cm
• Reposition tape & remeasure• Measures agree within 0.2 cm
Head Circumference
• Average at birth 35 cm
• Increases 1 cm/month 1st year
of life
• Most rapid growth first 6
months
Weight for Length
• <5th percentile undernutrition
• >95th percentile obesity
• Normal in constitutional growth delay or familial short stature
Body Mass Index (BMI)
• Screening tool for undernutrition and to diagnose overweight and obesity
• <15th percentile "at risk" for undernutrition
• 85th to 95th percentiles overweight
• ≥95th percentile obese
Corrections for Gestational AgePremature Babies
• Weight through 24 months of age
• Stature through 40 months of age
• Head circumference through 18 months of age
Special Growth Charts
• Turner syndrome
• Down syndrome
• William syndrome
• Achondroplasia
CDC versus WHO Growth ChartsCharacteristic CDC (2000) Growth
ReferenceWHO (2006) Growth Standard
Data Source US children Brazil, Ghana, India, Norway, Oman, California
Data collection Cross-sectional data starting at age 2 mos, Mathematical models used to connect birth weights and lengths to survey data
Longitudinal data with measurements at birth; 1, 2, 4, 6, and 8 wks; and 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 14, 16, 18, 20, 22, and 24 mos
Sample size 4,697 observations for 4,697 distinct children
18,973 observations for 882 distinct children
CDC versus WHO Growth ChartsCharacteristic CDC
(2000)WHO (2006)
Exclusions Very low birth weight (<1,500 g)
Low socioeconomic statusBirth at altitude >1,500 mBirth at <37 wks or ≥42 wksMultiple birthPerinatal morbiditiesChild health conditions known to affect growthMaternal smoking during pregnancy or lactationBreastfeeding for <12 mosComplementary foods <4 mos or >6 mosWt-for-length measurements >3 SD above or below study median for sex
CDC versus WHO Growth Charts
Characteristic CDC (2000) WHO (2006)Breastfeeding among infants in sample
Approximately 50% ever breastfed
Approximately 33% breastfeeding at 3 mos
100% ever breastfed
100% predominantly breastfeeding at 4 mos
100% still breastfeeding at 12 mos
Complementary foods introduced at mean age of 5.4 mos
Mean length measurements of children aged <24 monthsWHO multicentre Growth Reference Study, 2006
Acta Paediatr Suppl 2006;450:56--65
Comparison WHO & CDC growth chart weight-for-age <24 months
Girls Boys
Comparison WHO & CDC growth chart length/stature-for-age <5yrs
Girls Boys
CDC Recommendations
• WHO curves for children aged <24 months• First 3 months of age slower rate of weight
gain typical for formula fed infants• Differences in the length-for-age WHO and
CDC charts are small, and clinical differences based on these charts are expected to be insignificant
Height Velocity Curve
Hei
ght V
eloc
ity m
m/y
ear
Age (years)
Pre-pubertal dip
Pubertal Growth Spurt
5
10
15
25
20
7 9 111 3 5 13 15 17 19
Girls Boys
Normal Pubertal Development
• Maturation of the primary sexual characteristics
– Hypothalamic Pituitary Ovarian Axis
• Development of secondary sexual characteristics
– Sexual hair, Breasts, Genitalia
• Dramatic growth spurt
• Psychological changes: mental & emotional maturity
Female Breast Changes
Mature stagePapilla only
projects, areola recessed to
general contour of breast
Breast & areola enlarged &
elevated, no separation of
contours
PrepubertalElevation
papilla only
Breast budElevation of
breast & papilla small mound
Areola diameter enlarged
Areola &papilla form 2° above
contour of breast
B1 B2 B3 B4 B5
Pubic Hair Changes
Adult quantity & type
Spread to medial thighs
Darker, coarser, more curledSpreads over
junction of pubes
PreadolescentNo sexual hair
Sparse, long slightly
pigmented downy hair, base of penis or along
labia
Hair adult typeArea covered
smaller
PH2PH1 PH3 PH4 PH5
Spread along linea alba (typical male)PH6
Male Genital Changes
Adult size and shape
G1 G2 G3 G4 G5
Scrotum
Penis
Preadolescent
Preadolescent
slightly enlarged,
reddening of skin, changes in
texture
Little /no enlargement
Slightly enlarged, 1st length then
breadth
more enlarged
further enlarged, growth in breadth;
development of glans
further enlargement, darkening of
skin
Adult size and shape
Testicular Volume
Genital Stage
Testicular Volume
(ml)G1 1‒2 PrepubertalG2 3‒4 Beginning of pubertyG3 8‒10 Beginning of height acceleration G4 12‒15 Maximum growth velocity G5 20 Passed peak growth spurt
Epiphysis fusion
Puberty Girls
Age (years)10 11 12 13 14 158 9 16 17
Pubic hair
Breast
Menarche
Height spurt
2 3 4 5
2 3 4 58‒13 13‒18
10‒16.5
9.5‒14.5
Puberty Boys
Age (years)10 11 12 13 14 158 9 16 17
Pubic hair
Testis
Penis
Height spurt
2 3 4 5
9.5‒13.5 13.5‒17
10.5‒14.5
Genitalia rating 2 3 4 5
4 ml 12‒15 ml
12.5‒16.5
10.5‒16 13.5‒17.5
Developmental Assessment
• Early detection of deviation in child’s pattern of
development
• Simple and time efficient mechanism to ensure
adequate surveillance of developmental progress
Developmental Pattern
Head-to-toe direction (cephalocaudal)
Inward to outward pattern (proximodistal)
Principles of Development
• Continuous process related to maturation of CNS
• Same sequence of development
• Different rate of development
• Generalized mass activity replaced by specific individual responses
• Primitive reflexes lost before corresponding voluntary movement acquired
Developmental Domains
• Gross motor
• Fine motor adaptive
• Language
• Personal Social
• Hearing
• Vision
Malaysian Modification of Denver Developmental
Screening TestPersonal-
Social
Fine Motor-
Adaptive
Language
Gross MotorT Chen. Normal development of normal pre-school children. J Spore Paed Soc 1988;30:118
R Test Item
10 50 90
May pass by report
Gross Motor Assessment
Supine Pulled to sit Sitting
StandingVentral suspensionProne
Supine1 month
Head turn one side
L Arm extended
R Arm flexed
Knees apart, soles of feet turned inwards
Supine
3 months
Head midline
Waves arms symmetricallyHands loosely open
Brings hands together from sides into midline
Supine
Lifts leg vertical
6 months
Raise head from pillow to
look at feet
Grasps 1 foot, later 2 feet
Pulled to Sit
Marked head lag
Newborn
Head lags until body verticalAt vertical head held momentarily erect before falling forwards
1 month
Pulled to Sit
Little or no head lag
3-4 months
Braces shoulders &pulls himself to sit
6 months
Sitting
Completely rounded back
First 4 weeks
Rounded backHead up intermittently
1 month
Sitting
Back still rounded Raised head well Rounded lower lumbar
spine
4 months2 months
SittingSit without
support
7 months
Sit with hand support
6 monthsPivoting
11 months
Standing
Bearing almost all weight
5 monthsBearing some weight
3 months
Bears full weight
6 months
StandingWalks alone
Arms abducted, elbows flexed
Broad base gait
13 months
Stand with supportWalk holding on
11 months
Walks, 1 hand held
12 months
Ventral suspension
Head above line of bodyHips & shoulders extended
3 months
Head below plane of bodyLimbs hang downwards
Hips fully flexed
Newborn
Head in line with bodyHips semi-extended
1 month
PronePelvis high, Knees under abdomen
Pelvis flat; Hips extended
6-8 weeks
Pelvis lower, intermittent extension of hips
4-6 weeks
0-2 weeks
Prone
Weight on handsArms extended
6 months
Weight on forearmsPlane of face 90° to couch
3-4 months
Chin off couch intermittentlyPlane of face <45° to couch 6 weeks
Prone
Bear walking
12 months
Hands and knees crawling
9-10 months
Protective Reflexes
Forward ParachuteArms extend when suddenly lowered
towards couch
9 months
Lateral ParachuteArms extend laterally when child suddenly
tilted sideways during sitting
6-7 months
Downward ParachuteRapidly lowered; feet
meet ground plantigrade
5-6 months
Grasp
Intermediate grasp
7-8 months
Palmar grasp
4-6 months
Mature grasp
1 year
Grasp
Index approach
Finger thumb opposition
9 months
Fine Motor
Age (months) Milestones3 Grasp object when placed in hand4 Tries to reach object overshoots5 Reach & grasp; bidextrous approach6 Drops one cube when given another7 Unidextrous approach
Transfers objects from hand to handGrasp 2 cubes (one in each hand)
9 Pincer grasp
Fine Motor
Train with chimney 4 years
Tower of Cubes
Steps5 years
Bridge 3 years
18 mo
13-14 mo
2 yearsSteps4 years
Fine Motor
Age (yr) Milestone
1½ Imitates or scribbles spontaneously
2 Imitates vertical line or circular strokes
3 Copies circle
4 Copies cross
4½ Copies square
5 Copies triangle
Speech
Age (months) Milestones1-2 Coos2-6 Laughs and squeals8-9 Babbles: mama/dada10-12 Mama/dada specific 15 Jargon, several intelligible words18-20 20 to 30 words – 50% understood by strangers22-24 Two word sentences
>50 words, 75% understood by strangers30-36 Almost all speech understood by strangers
Personal Social
Age (mths) Milestones
1 Respond to cuddling
3 React to familiar situations
Shows pleasure to friendly handling
Regards mothers face during feeding
6 Still friendly to strangers
9 Stranger anxiety, plays peek-a-boo, imitates
hand clapping
Personal SocialWatches while plaything partly
hidden
Promptly finds it
Watches plaything
completely hidden
Distressed (Can’t find it)
9 months
Personal Social
Watches while toy hidden under cup
Regards & reaches for cup
Promptly finds toy
9 months
Personal Social
Plays pat-a-cakeExplores every
possibility of bell
12 months
Hearing
• 1 month– startled by sudden noises– turns head to voice
• 3 months– quieting or smiling to sound of mother’s voice– vocalizes delightedly when spoken to – may turn eyes and/or head towards sound-source– brows may wrinkle and eyes dilate
Development of Hearing
4 monthsHorizontal movement only in general direction of sound
5 monthsHorizontal movement followed by vertical movement in localizing sound below ear
6 monthsArc-like movement in localizing sound below ear
7 monthsDiagonal movement in localizing sound below ear
HearingAge (mths) Milestone
3 Turns to sound source
4Turns to sound source
Eyes look in same direction
5-6Turns to one side then downwards to sound made below ear
(1½ feet)
6 Turns to one side & then upwards to sound above ear
7-8 Turns head in curving arc towards sound
8-10 Turns head diagonally & directly towards sound
Free Field test
Tester
Distracter
Sound producing device
Parent
Child
Vision
Age (wks) Milestone
4 Follow dangling object (3ft from eyes) <90°
6 Follow to midline
8 Follow beyond midline
12 Follow 180°; hand regard
16 Regards dangling object immediately
Vision
Alert peripheral vision
Watches rolling ball 10 ft
9 months
Regards rolling ball 5-10 ft
6 months
Vision
Crawls to retrieve rolling ball
Points to mounted ball
12 months
Red Flags in Infant Development
• Unable to sit alone by age 9 months
• Unable to transfer objects from hand to hand by
age 1 year
• Abnormal pincer grip or grasp by age 15 months
• Unable to walk alone by 18 months
• Failure to speak recognizable words by 2 years