Groups of 100 diseases that develop across time. Characterized by uncontrolled cell division. Can...
-
Upload
britney-horton -
Category
Documents
-
view
214 -
download
0
Transcript of Groups of 100 diseases that develop across time. Characterized by uncontrolled cell division. Can...
![Page 1: Groups of 100 diseases that develop across time. Characterized by uncontrolled cell division. Can develop in virtually any of the body’s tissues. Hereditary.](https://reader035.fdocuments.in/reader035/viewer/2022062519/5697c0051a28abf838cc52f9/html5/thumbnails/1.jpg)
![Page 2: Groups of 100 diseases that develop across time. Characterized by uncontrolled cell division. Can develop in virtually any of the body’s tissues. Hereditary.](https://reader035.fdocuments.in/reader035/viewer/2022062519/5697c0051a28abf838cc52f9/html5/thumbnails/2.jpg)
• Groups of 100 diseases that develop across time.
• Characterized by uncontrolled cell division.
• Can develop in virtually any of the body’s tissues.
• Hereditary and environmental factors contribute to cancer factors.
• Second leading cause of death in U.S• Men have one in two lifetime risk,
women one in three
![Page 3: Groups of 100 diseases that develop across time. Characterized by uncontrolled cell division. Can develop in virtually any of the body’s tissues. Hereditary.](https://reader035.fdocuments.in/reader035/viewer/2022062519/5697c0051a28abf838cc52f9/html5/thumbnails/3.jpg)
• Benign
• Malignant
• Metastatic
*Type depends on cause and location
*Each type has its own growth rate, prognosis and treatability
![Page 4: Groups of 100 diseases that develop across time. Characterized by uncontrolled cell division. Can develop in virtually any of the body’s tissues. Hereditary.](https://reader035.fdocuments.in/reader035/viewer/2022062519/5697c0051a28abf838cc52f9/html5/thumbnails/4.jpg)
Benign T
umor
Malignant Skin Cancer
Metastatic Cancer
Cancer of the lip
![Page 5: Groups of 100 diseases that develop across time. Characterized by uncontrolled cell division. Can develop in virtually any of the body’s tissues. Hereditary.](https://reader035.fdocuments.in/reader035/viewer/2022062519/5697c0051a28abf838cc52f9/html5/thumbnails/5.jpg)
• Can inherit a cancer-susceptible mutation.
• Occurs in all the body’s cells.
![Page 6: Groups of 100 diseases that develop across time. Characterized by uncontrolled cell division. Can develop in virtually any of the body’s tissues. Hereditary.](https://reader035.fdocuments.in/reader035/viewer/2022062519/5697c0051a28abf838cc52f9/html5/thumbnails/6.jpg)
• Exposure to carcinogens• Cigarette smoking• Exposure to the sun• Females – family history of breast
cancer• Fair skin• Chemicals, radiation and viruses
![Page 7: Groups of 100 diseases that develop across time. Characterized by uncontrolled cell division. Can develop in virtually any of the body’s tissues. Hereditary.](https://reader035.fdocuments.in/reader035/viewer/2022062519/5697c0051a28abf838cc52f9/html5/thumbnails/7.jpg)
![Page 8: Groups of 100 diseases that develop across time. Characterized by uncontrolled cell division. Can develop in virtually any of the body’s tissues. Hereditary.](https://reader035.fdocuments.in/reader035/viewer/2022062519/5697c0051a28abf838cc52f9/html5/thumbnails/8.jpg)
• Incidence rate• Mortality rate• Survival rate
* Incidence Increases With age
![Page 9: Groups of 100 diseases that develop across time. Characterized by uncontrolled cell division. Can develop in virtually any of the body’s tissues. Hereditary.](https://reader035.fdocuments.in/reader035/viewer/2022062519/5697c0051a28abf838cc52f9/html5/thumbnails/9.jpg)
• Cancer represents a breakdown of the processes that regulate the growth of normal cells and tissues
• Cancer involves the uncontrolled division of body cells
![Page 10: Groups of 100 diseases that develop across time. Characterized by uncontrolled cell division. Can develop in virtually any of the body’s tissues. Hereditary.](https://reader035.fdocuments.in/reader035/viewer/2022062519/5697c0051a28abf838cc52f9/html5/thumbnails/10.jpg)
• Cell division is normally precisely regulated
• Cell cycle regulation is accomplished by two major types of genes
• Cancer-causing agents often damage genes
• When damage occurs to genes that regulate the cell cycle, signals that inhibit cell division can change leading the cell to divide more often than it normally would
![Page 11: Groups of 100 diseases that develop across time. Characterized by uncontrolled cell division. Can develop in virtually any of the body’s tissues. Hereditary.](https://reader035.fdocuments.in/reader035/viewer/2022062519/5697c0051a28abf838cc52f9/html5/thumbnails/11.jpg)
• Cancer develops from genetic damage to cells across time
• Cancer research leads to understanding normal cell cycle and new strategies for treating cancer
![Page 12: Groups of 100 diseases that develop across time. Characterized by uncontrolled cell division. Can develop in virtually any of the body’s tissues. Hereditary.](https://reader035.fdocuments.in/reader035/viewer/2022062519/5697c0051a28abf838cc52f9/html5/thumbnails/12.jpg)
1. Mutation2. Hyperplasia3. Dysplasia4. In situ cancer
(tumor)5. Invasive cancer
(malignant)
![Page 13: Groups of 100 diseases that develop across time. Characterized by uncontrolled cell division. Can develop in virtually any of the body’s tissues. Hereditary.](https://reader035.fdocuments.in/reader035/viewer/2022062519/5697c0051a28abf838cc52f9/html5/thumbnails/13.jpg)
1. Shape changes2. Changes in their dependence on
growth factors3. Multitude of biochemical
differences
![Page 14: Groups of 100 diseases that develop across time. Characterized by uncontrolled cell division. Can develop in virtually any of the body’s tissues. Hereditary.](https://reader035.fdocuments.in/reader035/viewer/2022062519/5697c0051a28abf838cc52f9/html5/thumbnails/14.jpg)
![Page 15: Groups of 100 diseases that develop across time. Characterized by uncontrolled cell division. Can develop in virtually any of the body’s tissues. Hereditary.](https://reader035.fdocuments.in/reader035/viewer/2022062519/5697c0051a28abf838cc52f9/html5/thumbnails/15.jpg)
• Increased incidence of cancer with age
• Development of cancer decades after exposure to carcinogens
• Increased incidence of cancer among people with inherited dispositions
![Page 16: Groups of 100 diseases that develop across time. Characterized by uncontrolled cell division. Can develop in virtually any of the body’s tissues. Hereditary.](https://reader035.fdocuments.in/reader035/viewer/2022062519/5697c0051a28abf838cc52f9/html5/thumbnails/16.jpg)
![Page 17: Groups of 100 diseases that develop across time. Characterized by uncontrolled cell division. Can develop in virtually any of the body’s tissues. Hereditary.](https://reader035.fdocuments.in/reader035/viewer/2022062519/5697c0051a28abf838cc52f9/html5/thumbnails/17.jpg)
• Individual behavior changes• Health care providers – counseling and
screening• National level – government regulations
to minimize public exposure to known carcinogens
• International level – actions of developed countries bring cancer worldwide
![Page 18: Groups of 100 diseases that develop across time. Characterized by uncontrolled cell division. Can develop in virtually any of the body’s tissues. Hereditary.](https://reader035.fdocuments.in/reader035/viewer/2022062519/5697c0051a28abf838cc52f9/html5/thumbnails/18.jpg)
![Page 19: Groups of 100 diseases that develop across time. Characterized by uncontrolled cell division. Can develop in virtually any of the body’s tissues. Hereditary.](https://reader035.fdocuments.in/reader035/viewer/2022062519/5697c0051a28abf838cc52f9/html5/thumbnails/19.jpg)
• Excessive exposure to UV radiation• Fair complexion• Occupational exposure to
substances– Coal tar– Creosote– Arsenic compounds– Radium