Gregor Mendel. . . . . .and his pea plants 1860s The establishment of ...
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Gregor Mendel. . . . . .and his pea plants 1860s
The establishment of genetics
Fruitfly: Drosophila melanogaster
Thomas Hunt Morgan
1920’s
Escherichia coli Jacques Monod
Lambda phage virus
Esther Lederberg
Mouse
Arabidopsis thaliana
Friedrich Laibach
Yeast: Saccharomyces cerevisiae
Pub patrons everywhere
Caenorhabditis elegans
Sydney Brenner
Zebrafish George Streisinger
Caenorhabditis elegans
Primary spermatocyte
Secondary spermatocytes
Residual body
Spermatid
Spiky intermediate
Pseudopod formation
Spermatozoon
Spermiogenesis
fertilization
Mutation analysis
spe-46 spe-47
spe-46 spe-47
spe-6
spe-26, spe-4, spe-5
fer-2, fer-6
fer-3, fer-4 fer-15
spe-8, spe-12, spe-19, spe-27, spe-29
fer-1, spe-10, spe-17
fer-14, spe-9, spe-13, spe-16
spe-11
spe-44
1. How would you create a strain that had both green peas and white flowers?
2. How could you tell if the genes responsible for pea and flower color are on the same chromosome?
3. What is causing the phenotypes and how is it affecting the genes?
4. What could you do to create more phenotypes?
Gene Chromosome Genome Locus Linkage Allele Epistasis Pleiotropy Mutation Segregation Monohybrid cross Dihybrid cross Independent assortment Recombination Homologous chromosome
Gain of function Loss of function Sex linked Map units Genetic map Physical map Complementation test