W W W . I M E D E X . C O M

April 15-16, 2011New York, New York

Chairs:Marla C. Dubinsky, MD Cedars-Sinai Medical Center Los Angeles, California

Asher A. Kornbluth, MD Mount Sinai School of Medicine New York, New York

Joel R. Rosh, MD Goryeb Children’s Hospital Atlantic Health System Morristown, New Jersey

Robbyn Sockolow, MDWeill Cornell Medical College New York, New York

Great Debates and Updates in

Inflammatory Bowel Disease

1st Announcement

Great Debates and Updates in

Inflammatory Bowel Disease

April 15-16, 2011 – New York, New York

FACULTYMaria Abreu, MD University of Miami Miller School of Medicine Miami, Florida

Robert N. Baldassano, MD Children’s Hospital of Philadelphia University of Pennsylvania Philadelphia, Pennsylvania

Keith J. Benkov, MD Mount Sinai Medical Center New York, New York

Jean-Frédéric Colombel, MD Mount Sinai School Medicine New York, New York

Marla C. Dubinsky, MD Cedars-Sinai Medical Center Los Angeles, California

Sonia Friedman, MD, FACG Harvard Medical School Brigham and Women’s Hospital Boston, Massachusetts

Jeffrey S. Hyams, MD University of Connecticut School of Medicine Connecticut Children’s Medical Center Hartford, Connecticut

Asher A. Kornbluth, MD Mount Sinai School of Medicine New York, New York

James Markowitz, MD Steven and Alexandra Cohen Children’s Hospital of New York North Shore-LIJ Health System New Hyde Park, New York

Scott Plevy, MD University of North Carolina at Chapel Hill Chapel Hill, North Carolina

Miguel Regueiro, MD University of Pittsburgh Medical Center Pittsburgh, Pennsylvania Joel R. Rosh, MD Goryeb Children’s Hospital Atlantic Health Systems Morristown, New Jersey

David T. Rubin, MD University of Chicago Medical Center Chicago, Illinois

Robbyn E. Sockolow, MD New York-Presbyterian Weill Cornell Medical Center New York, New York

Francisco A. Sylvester, MD University of Connecticut School of Medicine Connecticut Children’s Medical Center Hartford, Connecticut

Eva M. Szigethy, MD, PhD University of Pittsburgh & Children’s Hospital of Pittsburgh Pittsburgh, Pennsylvania

Thomas A. Ullman, MD Mount Sinai School of Medicine New York, New York

Corporate SupportThe following companies have provided an educational grant in support of this conference:

Gold

Silver

Several options are available to companies interested in supporting this conference. For more information, please contact Imedex at +1 (770) 751 7332, or by email at cme@imedex.com.

Call for ExhibitorsExhibit space is available to companies interested in participating in this conference through exhibition. For more information, please contact Imedex at +1 (678) 242 0719 or by email at exhibits@imedex.com.

Conference Organizer

11675 Rainwater Drive, Ste 600 Alpharetta, Georgia 30009, USA Tel.: +1 (770) 751 7332 Fax: +1 (770) 751 7334 Email: meetings@imedex.com www.imedex.com

Physicians

Imedex®, LLC is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Imedex®, LLC designates this educational activity for a maximum 11.0 of AMA PRA Category 1 CreditTM. Physicians should only claim credit commensurate with the extent of their participation in the activity.

Who Should Attend/Target Audience

This educational activity is designed for gastroenterologists, hospitalists, internists, physician assistants, nurses, surgeons, and other clinicians with an interest in treating patients with IBD inclusive of children, teens, and young adults.

• Review at least three diagnostic tools that can increase the optimization of diagnosing IBD

• Employ evidence-based criteria when selecting patients for early use of biologic therapies

• Identify at least two differences between monotherapy and concomitant therapy during the post-SONIC era

• Recall at least one way to maximize the efficacy and reduce the risk of commonly used immunomodulators and biologics

• Identify at least two strategies to manage naïve patients and patients that have not responded to therapy

• Discuss whether steroid therapy should be abandoned in children, teens, and young adults

• Restate the impact of enteral nutrition on therapy

• Summarize best practices regarding cancer prevention and detection strategies

• Identify at least two strategies to maintain skeletal health in children, teen, and young adult patients

• Devise at least one strategy to psychologically manage juvenile IBD patients

• Discuss the importance of post-op maintenance

• Restate at least one benefit of using mucosal healing as a standard therapeutic endpoint

• Select the optimal pharmacologic therapy for pregnant women with IBD

• Review the impact of biomarkers on guiding therapy options

Learning Objectives

Upon completion of this activity, participants should be able to:

Continuing Medical Education

Friday, April 15, 2011MasterClass: Management of IBD in Children, Teens, and Young Adults

Co-chairs: Joel R. Rosh, MD and Robbyn Sockolow, MD

1:00 pm Welcome and pre-activity audience knowledge/competence assessment via ARS Joel R. Rosh, MD Robbyn E. Sockolow, MD

1:15 pm Implementing new diagnostic imaging tools

Case presentations with audience participation via ARS Robbyn E. Sockolow, MD

1:45 pm Introducing biologics into therapy

Case presentations with audience participation via ARS Jeffrey S. Hyams, MD

2:15 pm Debate: Optimal therapy during post-SONIC Era Point: Monotherapy Joel R. Rosh, MD

Counterpoint: Concomitant therapy Jeffrey S. Hyams, MD

2:45 pm Debate: Should we abandon steroid therapy? Point: Yes, we should abandonFrancisco A. Sylvester, MD

Counterpoint: No, steroid therapy is a viable option Keith J. Benkov, MD

3:15 pm Coffee break

3:35 pm What role does enteral nutrition have in therapy?

Case presentations with audience participation via ARSRobert N. Baldassano, MD

4:05 pm When should you initiate cancer screening?

Case presentations with audience participation via ARS James Markowitz, MD

4:30 pm How to optimally maintain skeletal health

Case presentations with audience participation via ARSFrancisco A. Sylvester, MD

4:55 pm Psychological management of patients Eva M. Szigethy, MD, PhD

5:20 pm Conclusion and post-activity audience knowledge/competence assessment via ARS

5:30 pm Adjourn

Saturday, April 16, 2011Practical Insights in the Management of IBD

Co-chairs: Marla C. Dubinsky, MD, and Asher A. Kornbluth, MD

8:00 am Welcome and pre-activity audience knowledge/competence assessment via ARS Marla C. Dubinsky, MD and Asher A. Kornbluth, MD

8:15 am Management of pregnant women with IBD Maria Abreu, MD

8:40 am Vaccinations and other health maintenance issues for the patient on immune suppressive therapies Sonia Freidman, MD, FACG

Great Debates and Updates in

Inflammatory Bowel Disease

April 15-16, 2011 – New York, New York

Scientific Agenda

9:05 am Debate: Once you start biologics/immunomodulators, you cannot stop Moderator: Asher A. Kornbluth, MD

Point: YesMiguel Reguerio, MD

Counterpoint: No, it is feasible to stop therapy Maria Abreu, MD

9:45 am Small bowel imaging – Choosing the best radiologic modalities Speaker invited

10:00 am Non radiologic imaging of the small bowel: Capsule endoscopy and double balloon enteroscopy Asher A. Kornbluth, MD

10:15 am Question & answer

10:30 am Coffee break

10:50 am Optimization of biologic treatment in biologic naive patients Jean-Frédéric Colombel, MD

11:05 am Optimization of biologic treatment in patients losing response to an anti-TNF agent Scott Plevy, MD

11:20 am Question & answer

11:35 am Debate: Mucosal healing is the key therapeutic endpoint Moderator: Marla C. Dubinsky, MD

Point: YesThomas A. Ullman, MD, FACG

Counterpoint: Symptoms should be the endpoint David T. Rubin, MD, FACG

12:10 pm Debate: Post-op anti-TNF is necessary for all patients Moderator: Scott Plevy, MD

Point: YesMiguel Regueiro, MD

Counterpoint: NoAsher A. Kornbluth, MD

12:45 pm Lunch break Meet the experts Attendees will have the opportunity to talk to the faculty in small, round table discussions

1:45 pm Update on prognostics: Will biomarkers help guide therapy for your IBD patients? Marla C. Dubinsky, MD

2:10 pm Balancing and explaining risks to the patient Jean-Frédéric Colombel, MD

2:35 pm State of the art lecture: Cancer screening and management decisions David T. Rubin, MD, FACG

3:00 pm Coffee break

3:30 pm Gastroenterology Board review – Clinical cases and questions for the practicing gastroenterologist and GI Fellow preparing for Board certification or recertification

Moderators: Asher A. Kornbluth, MD and Marla C. Dubinsky, MD

Faculty panel: Jean-Frédéric Colombel, MD, Sonia Friedman, MD, FACG, Scott Plevy, MD, Miguel Regueiro, MD, David T. Rubin, MD, FACG

4:35 pm Conclusion and wrap-up summary

4:45 pm Adjourn

Please visit www.imedex.com for the most up-to-date program and to register.

Conference Location and Hotel Accommodations

Westin New York at Times Square 270 West 43rd Street New York, New York 10036 Tel.: +1 (212) 201 2700 Fax: +1 (212) 201 2701 www.westinny.com

The Westin New York at Times Square is located at 43rd Street and 8th Avenue, in the heart of the Broadway District with 40 theatres within walking distance. It is surrounded by the New York fashion, financial and commercial districts with easy access to the city’s subway system and within blocks of Penn Station and Grand Central Station. It is close to spectacular sights, city landmarks and incredible shopping.

For the convenience of attendees, a room block with a limited number of rooms has been reserved at the discounted group rate of $239 single/double occupancy, plus tax, currently at 14.75% plus a $2.00 per day occupancy charge and a daily hotel unit fee of $1.50. This limited number of discounted rooms will be available until March 25, 2011. This discounted rate is not guaranteed outside the conference dates. Reservations received after March 25, 2011 or after the room block has been filled (whichever comes first) are subject to availability and prevailing hotel rates.

To reserve your room please contact the Westin New York at Times Square Central Reservations Office at +1 (888) 627 7149 and mention “Great Debates and Updates in IBD”.

Reservations can also be made by clicking here: http://www.starwoodmeeting.com/Book/atesAndUpdatesInIBDAttendees.

Note: Early Departure Fee – An early departure fee of $100 will apply if you reserve a room and check out prior to the confirmed checkout date.

Discounted ________________ $150Payment received by March 17, 2011

Regular ____________________ $200Payment received by April 6, 2011

Full/Onsite _________________ $250If payment received after April 6, 2011

Group with Discounted Fees: Nurses/Residents/Students* ____ $99*Proof of eligibility must accompany registration; cannot be combined with any other discounts.

Registration Fees

To Register: You may register online by April 6, 2011 at www.imedex.com, by calling Imedex at +1 (678) 242 0906 or by returning the registration form in this program by mail or fax. If you mail the form, please keep a copy for your records. Registration confirmations will be issued before the meeting.

To qualify for special registration fees, registration and full payment must be received by Imedex by the dates specified.

Payment: To pre-register, registration and payment must be received no later than April 6, 2011. Please register onsite after this date. Contact Imedex at +1 (678) 242 0906 or visit our website at www.imedex.com to ensure the course is being held as scheduled and to confirm that the meeting is not full.

Registration fees must be remitted by credit card or check. Checks should be payable to Imedex. Attendee is not registered until full payment is received.

Registration Fee Inclusions: Registration fees include admittance to all scientific sessions, conference materials, processing of certificates of attendance or continuing medical education, and all event functions as specified in the agenda.

Cancellation: For registration fees to be refunded, written notice of cancellation must be received at meetings@imedex.com no later than April 6, 2011. The amount of registration fees remitted, minus a $75 administrative charge, will be refunded after the conference. Substitutions are accepted with written notification. No refunds will be made if notice is received after April 6, 2011.

Imedex does not accept responsibility for covering travel, accommodation or any other costs incurred by registrants in the rare event that this meeting should be canceled for any reason. Every effort will be made to give reasonable notice in the event of cancellation. The event agenda is subject to change without notice.

The Registration and Information Desk at the Westin New York at Times Square will be staffed:

Friday, April 15, 2011 ________ 11:30 am – 5:30 pmSaturday, April 16, 2011 ______ 6:00 am – 4:45 pm

Imedex does not accept responsibility for covering travel, accommodation or any other costs incurred by registrants in the rare event that this meeting should be canceled for any reason. Every effort will be made to give reasonable notice in the event of cancellation. The event agenda

content is subject to change without notice.

_______________________________________________________________________________________ FIRST NAME LAST NAME MI

DEGREE: qMD qPhD qPA q NP q RN qOther Degree ______________________________________ SPECIALTY: qGastroenterology qPediatrics or Pediatric Gastroenterology qNursing qInternal Medicine

qSurgery qOther ________________________________________________________________________ ________________________________________________________________________________________ EMAIL ADDRESS ________________________________________________________________________________________ TELEPHONE FAX ________________________________________________________________________________________ INSTITUTE DEPARTMENT ________________________________________________________________________________________ ADDRESS

________________________________________________________________________________________ CITY STATE / PROVINCE

________________________________________________________________________________________ ZIP / POSTAL CODE COUNTRY

A252.01C O N F E R E N C E R E G I S T R AT I O N

Credit card transactions will appear under the name Imedex Inc. on your next statement.

NOTE: Registrants that pay with American Express will be charged in the USD equivalent which may incur additional charges. This is a policy of American Express. Foreign exchange rate information may be found at www.oanda.com. After April 6, 2011 only credit card payments will be accepted for pre-registration.

To pre-register, registration and payment must be received no later than April 6, 2011. Please register onsite after this date. Contact Imedex at +1 (678) 242 0906 or visit our website at www.imedex.com to ensure that the meeting is being held as scheduled and to confirm that the meeting is not full.

For registration fees to be refunded, written notice of cancellation must be received at meetings@imedex.com no later than April 6, 2011. The amount of registration fees remitted, minus a $75 administrative charge, will be refunded after the conference. Substitutions are accepted with written notification. No refunds will be made if notice is received after April 6, 2011.

qAmerican Express qMasterCard qVisa

qCheck in the amount of $____________________________________________________________

Card No. ____________________________________________ Exp. Date: __________/__________

PAY M E N T M E T H O D

R E G I S T R AT I O N F E E S

q Check if you require special facilities or assistance and attach a note with specific details and requirements.

q $150 Discounted Payment received by March 17, 2011

q $200 RegularPayment received by April 6, 2011

q $250 Full/OnsiteIf payment received after April 6, 2011

q $99 Nurses/Residents/Students*

*Proof of eligibility must accompany registration; cannot be combined with any other discounts.

Four EASY ways to register:

Great Debates and Updates in

Inflammatory Bowel Disease

April 15-16, 2011 New York, New York

ONLINE. . .www.imedex.com

FAX +1 (678) 242 0920

C ALL +1 (678) 242 0906

MAIL US. . .Imedex®

11675 Rainwater Dr. Suite 600 Alpharetta, GA 30009

1167

5 R

ain

wat

er D

r., S

uit

e 60

0. A

lph

aret

ta, G

A 3

0009

Dar

k B

lue

C10

0, M

55, Y

0, K

55

Lig

ht

Blu

e C

29, M

12, Y

0, K

0

Ora

ng

e C

0, M

66, Y

100,

K0

Gre

at D

ebat

es a

nd

Up

dat

es in

Infl

am

ma

tory

B

ow

el D

isea

seA

pri

l 15-

16, 2

011

– N

ew Y

ork

, New

Yo

rk

Impo

rta

nt D

ate

sD

isco

un

ted

Reg

istr

atio

n D

ead

line

Mar

ch 1

7, 2

011

Reg

ula

r Reg

istr

atio

n D

ead

line

Ap

ril 6

, 201

1

Pre

sen

tati

on

Dat

es

A

pril

15,

201

1

AU

DIE

NC

E P

AR

TIC

IPA

TIO

N

A H

AN

DS

-ON

EX

PE

RIE

NC

E

Dur

ing

the

scie

ntifi

c se

ssio

ns, s

pea

kers

and

the

aud

ienc

e ca

n

exch

ange

info

rmat

ion

thro

ugh

a “h

and

s-on

” com

put

eriz

ed s

pea

ker-

aud

ienc

e in

tera

ctio

n sy

stem

. With

this

sta

te-o

f-th

e-ar

t eq

uip

men

t, p

artic

ipan

ts a

nsw

er m

ultip

le c

hoic

e q

uest

ions

, and

with

in s

econ

ds,

the

answ

ers

are

calc

ulat

ed a

nd p

roje

cted

on

a sc

reen

in ta

bul

ar

or g

rap

hic

form

for a

ll to

see

. Thi

s sy

stem

max

imiz

es th

e ab

ility

for

atte

ndee

s fr

om d

iver

se d

isci

plin

es to

see

diff

erin

g op

inio

ns a

nd

com

par

e co

nsen

sus

bet

wee

n th

e sp

eake

rs a

nd e

ach

othe

r.

Imed

ex®

is a

bra

nd a

nd a

ssum

ed n

ame

used

by

Imed

ex, L

LC (h

ereb

y re

ferr

ed to

as

Imed

ex).

Imed

ex is

so

lely

resp

onsi

ble

for t

his

agen

da’

s co

nten

t. A

lthou

gh

Imed

ex a

ttem

pts

to e

nsur

e th

at th

e in

form

atio

n in

our

p

rogr

am is

acc

urat

e an

d ti

mel

y, m

atte

rs a

nd o

pin

ions

d

iscu

ssed

and

/or p

rese

nted

with

resp

ect t

o cl

inic

al

mat

ters

are

thos

e of

the

dis

cuss

ion

par

ticip

ants

onl

y, an

d n

ot n

eces

saril

y th

ose

of Im

edex

. Mor

eove

r, al

thou

gh

Imed

ex a

ttem

pts

to id

entif

y an

d in

tegr

ate

the

mos

t q

ualifi

ed m

edic

al p

rofe

ssio

nals

in o

ur p

rogr

am, T

O

THE

FULL

EST

EXTE

NT

PERM

ITTE

D B

Y LA

W, IM

EDEX

EX

PRES

SLY

DIS

CLA

IM A

LL W

ARR

AN

TIES

, EIT

HER

EX

PRES

S O

R IM

PLIE

D, S

TATU

TORY

OR

OTH

ERW

ISE,

INC

LUD

ING

BU

T N

OT

LIM

ITED

TO

TH

E IM

PLIE

D W

ARR

AN

TIES

OF

MER

CH

AN

TABI

LITY

, NO

N-IN

FRIN

GEM

ENT

OF

THIR

D

PART

IES’

RIG

HTS

, AN

D F

ITN

ESS

FOR

A P

ART

ICU

LAR

PURP

OSE

, WIT

H R

ESPE

CT

TO T

HE

CON

TEN

T PR

ESEN

TED

. IM

EDEX

FU

RTH

ER M

AKE

S N

O R

EPRE

SEN

TATI

ON

S O

R W

ARR

AN

TIES

ABO

UT

THE

ACC

URA

CY,

RELI

ABI

LITY

, CO

MPL

ETEN

ESS

OR

TIM

ELIN

ESS

OF

THE

CON

TEN

T O

R A

NY

MAT

ERIA

L PR

ESEN

TED

.

In a

dd

ition

, the

mat

eria

l pre

sent

ed a

nd re

late

d

dis

cuss

ions

are

not

inte

nded

to b

e m

edic

al a

dvi

ce, a

nd

the

pre

sent

atio

n or

dis

cuss

ion

of s

uch

mat

eria

l is

not

inte

nded

to c

reat

e an

d d

oes

not e

stab

lish

a p

hysi

cian

-p

atie

nt re

latio

nshi

p. M

edic

al a

dvi

ce o

f any

nat

ure

shou

ld

be

soug

ht fr

om a

n in

div

idua

l’s o

wn

phy

sici

an.

Nei

ther

Imed

ex n

or a

ny o

f its

sub

sid

iarie

s or

affi

liate

s is

af

filia

ted

with

or f

orm

ally

end

orse

d b

y a

med

ical

soc

iety

.

© 2

011

Imed

ex®,

LLC

. All

right

s re

serv

ed. R

epro

duc

tion

in

who

le o

r par

t is

pro

hib

ited

with

out p

rior w

ritte

n co

nsen

t fr

om Im

edex

and

con

trib

utin

g fa

culty

.

An

exci

ting

new

eve

nt f

or h

ealt

hca

re p

rofe

ssio

nals

! E

xper

t F

acu

lty

Pra

ctic

al I

nsig

hts

E

nga

gin

g

Inte

ract

ive