Grand Round Sampling of Interesting Dermatopathology Cases
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Transcript of Grand Round Sampling of Interesting Dermatopathology Cases
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Sampling of a few interesting dermatopathology cases
from CUMC
Belly button fuzz ball, red
palms, non-fitting prostheticleg, red wine glass etc.
Deba P Sarma, MD
Director of Dermatopathology
Creighton University Medical Center
Dept Pathology, Omaha
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Dermatopathology articles from
CUMC Dept of Pathology
2006 to 2009
Total: 59
Pubmed indexed: 15Non-Pubmed indexed: 44
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A 55-year-old obese woman
4-month history of hemorrhagicdischarge from the umbilicus
8-mm dark mass from baseof the umbilicus
Case 1
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Diagnosis: Lint ball omphalitis
Ref:
Sarma DP,Teruya B (2009). Lint ball omhphalitis, a
rare cause of umbilical discharge in an adult woman: a
case report. Cases J 2: 7785 PMID:19830013.[Pubmed-indexed for MEDLINE].
Steinhauser G (2009).The nature of navel fluff. MedHypotheses. 72(6):623-5.
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50-year-old man
Possible pilar cyst removed from scalp.
Case 2
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RCC immunostain
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Implantation carcinoma of the scalp from renal
cell carcinoma
Ref:
Sarma DP, Wang JF, McAllister MV, Wang B, Shehan
JM. (2008) Possible implantation carcinoma of the scalp
following craniotomy for metastatic renal cellcarcinoma. Dermatology Online J 14(6):20. PMID:
18713600 [PubMed - indexed for MEDLINE]
Diagnosis:
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44-year old man of Chinese heritage whohad red hands since birth
74-year-old mother and 7-year-old daughteralso had bright red palms all their life
Case 3
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Erythema palmare hereditarium
(Red palm disease, Lanes disease)
Ref:Sarma DP, Wang B (2007). Erythema palmarehereditarium (Red palms): Lanes Disease. DermatolOnline J. 13(2). PMID: 17498447 [PubMed - indexed for MEDLINE]
Lane JE. Erythema palmare hereditarium. Arch DermSyph. 1929; 445-448.
Diagnosis
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58-year-old man with left knee dislocation with
neurovascular injury in 1968.
Left below the knee amputation, fitted with an artificialleg.
36 years later in 2004, pain at the amputation site, mass,foul discharge.
Case 4
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Verrucous carcinoma in the amputation stump
Ref:
Sarma DP, Hansen TP, Adickes ED(2006):
Carcinoma arising in the leg amputation stump.
The Internet J Dermatol 4(1). Indexed in
Google Scholar.
Diagnosis
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Sarma DP, Weilbaecher TG. Carcinoma arising in burn scar.
J Surg Oncol. 1985 Jun;29(2):89-90.
A 60-year-old man had Lt BK amputation 30 years ago after adynamite explosion injury.
Artificial leg since then.
Developed squamous cell carcinoma on the amputation stump30 years later.
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Three skin biopsies from the face of three
men (age: 55-67yrs)
Case 5
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Winer L H. The dilated pore, a trichoepithelioma. J
Invest Dermatol 1954; 23(3):181-188.
Sarma Deba P.(2009): Dilated Pore of Winer, Dr. LouisH Winer and Wine Glass. The Internet Journal of
Dermatology Vol 7(2).
Ref
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Woman, 32 yrs
5 mm, painless subareolar nodule, left breast
Case 6
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Diagnosis:
Infiltrating syringomatous eccrine
adenoma of the nipple
Ref:
Sarma D, Stevens T (2009). Infiltrating syringomatouseccrine adenoma of the nipple: a case report. Cases J 2:0118.
PMID:20062695 [Pubmed-indexed for MEDLINE]
C 7
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Case 7
83-yr-old female, 7-mm painless soft papule, left
cheek, present for few months
Clinical lipoma
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CK 20Chromogranin Synaptophysin
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Diagnosis:
Subcutaneous Merkel cell carcinoma
Ref
Sarma DP, Heagley D, Chalupa J, Cox M, Shehan JM.
An unusual clinical presentation of Merkel cell
carcinoma. Case Reports in Medicine