Gold_Effective Programming Calcium Supplementation and Pre Eclampsia Eclampsia

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    Effective Programming:

    Calcium Supplementationand Pre-

    eclampsia/eclampsia

    Presented by:

    Emily Gold

    14 April, 2013

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    Objectives of this presentation

    Highlight gaps in our knowledge needed for the

    translation of the evidence into program design and

    initiate a discussion on appropriate ways to move

    programs forward while awaiting this additionalevidence

    Reflect on lessons from IFA programming that can be

    applied to Calcium supplementation programs

    Share preliminary findings from research underway

    in collaboration with Cornell University

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    Current research (including randomized control trials)

    do not provide critical information for the design of

    programs

    What is appropriate delivery strategy for calcium?

    Will calcium supplementation inhibit absorption of

    iron?

    How can IFA programs and Ca. supplementation

    programs co-exist/ be integrated?

    How do we ensure high compliance?

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    The impact in a program does not depend only on the

    biological potential but also the potential of the program to

    deliver the intervention

    Calcium

    supplementreceived

    ABSORPTION ANDBIOLOGICAL

    PATHWAYSReducedpreeclampsia

    Inadequate calcium

    intake

    Timely care-seeking

    during pregnancy

    Calcium

    supplementconsumed

    regularly

    Calcium

    supplement

    available

    Care provider

    knows to give Ca,

    provides education

    to use

    Side effects

    managed

    Procurement

    and distribution

    Culture, traditions,

    availability of services

    Barriers managed (e.g.

    Memory, acceptance,

    taste, etc)

    Quality of services and

    counselling

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    External Factors

    Socio-cultural

    Technical Economic

    Political

    Provision

    Quantity

    Quality

    Timeliness

    Uptake

    Awareness

    Attitude

    Accessibility

    Utilization

    Uptake + Knowing benefits &

    how to use + External

    motivation

    Impact

    Nutritional Need + Coverage + Utilization

    Impact of interventions dependant on multiple factors

    Contextually relevant package of interventions

    Coverage

    Provision +

    Uptake by those in

    need

    NEED

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    Some of the challenges that we have seen for IFA programs

    are likely to be similar for Calcium supplementation programs

    Demand side:

    Contact with women may begin only late in pregnancy

    Irregular and infrequent contact may limit effectivecoverage, opportunities for encouragement to comply

    Care providers may not be effective to council compliance Possible issues with uptake and compliance

    Lack of information on managing side effects

    Supply side:

    Budget allocation donor dependency

    Poorly functioning supply chains

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    Some of the challenges that we have seen for IFA programs

    are likely to be similar for Calcium supplementation programs

    Demand side:

    Contact with women may begin only late in pregnancy

    Irregular contact may limit effective coverage,

    opportunities for encouragement to comply Possible issues with uptake and compliance

    Supply side:

    Budget allocation donor dependency

    Poorly functioning supply chains

    Although well recognized, many of these issues

    have not been adequately addressed for IFAprograms. Now we should:

    Avoid Ca programs likely to suffer from similar

    supply and demand-side problems

    Take advantage to renew efforts to strengthen

    IFA and Ca programs simultaneously

    Be aware of additional challenges related to

    compliance and interactions

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    .:.

    MIs Maternal and Neonatal Health and

    Nutrition Program

    MIs Maternal and Neonatal Health and

    Nutrition Program

    Some lessons learnt and common

    sense responses to these challenges

    Intense and effective training will be required for

    health care providers

    Motivation to accept and implement programs

    effectively, including supply management andcommunication with pregnant women

    Alternative delivery strategies should be

    examined

    Effective behaviour change communication Requires an understanding of the barriers and

    factors that would facility uptake and

    adherence

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    MIs Calcium project (Ethiopia and Kenya) to be

    implemented in 2 phases to address specific challenges

    for program design. In Phase 1:

    , 2006.

    Challenge 1: Low uptake of IFA, low ANC and late /infrequent contact

    with health care system

    Potential for greater risk with additional supplement (larger,

    additional tablet, side effects etc.)

    Aiming to identify optimal delivery platform

    .:.

    Challenge 2: Poor compliance with IFA supplementation

    Potential for greater risks with addition of calcium

    Collecting and assimilate information on the perspectives ofhealth

    care providers and beneficiaries to inform BCI

    Designing models for delivery and promotion of Ca and IFA

    supplements in pregnancy.

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    Some results from Phase 1:

    FAQs Calcium Supplementation include:

    Dosage- better bioavailability when taken in smaller (< 500 mg)divided doses

    Formulation-benefits of both Ca. Carbonate and Ca. Citrate

    Malate. Time of dosing can affect absorption depending on

    formulation

    Malaria- at this time there are no data or evidence to suggest

    that calcium interacts with typical anti-malarial drugs

    FAQs IFA lessons for Calcium include:

    Successful strategies for improving ANC

    Successful strategies for improving supplies of supplements

    Successful strategies for improving adherence

    Alternate ways of reaching women with micronutrients

    Discussion paper on implications of new Ca recommendation for

    biomedical practices

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    Trial of Improved Practice (TIPs) methodology used to

    test delivery, acceptance and compliance with several

    dosages and regiments of Calcium and IFA supplements

    in Kenya and Ethiopia

    Test of 2 delivery systems

    Explore innovative packaging ideas to limit cost &

    complexity &permit procurement

    Explore potential to reduce calcium dosage without

    compromising impact

    Next steps in Phase 1:

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    Phase 2 will include pilot testing the new delivery

    model in both countries

    , 2006.

    Objective 1: Test models developed in Phase 1 by implementingCa and IFA supplementation within the health system

    Objective 2: Evaluate the implementation process and

    effectiveness of the model strategies.

    Objective 3: Refine models and make recommendations for

    improving implementation and effectiveness.

    Objective 4: Disseminate results to provide policy makers,

    program developers and health care providers

    .:.

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    Some countries may wish to move programs forward before

    results from these studies are available a few suggestions in

    doing so:

    Programs in all countries should invest in the formative researchand information collection that will ensure appropriate program

    design in their context:

    Innovative alternatives for delivery (particularly if IFA programs

    have not been successful) Eg. Using community level health agents

    Identification and resolution of forecasting and supply chain

    issues for IFA and Calcium

    Effective training for health care providers and relevant andeffective communication to promote update and utilization

    Requires understanding of the barriers that they perceive both

    for providers and pregnant women and those who may influence

    their decision related to ANC and supplement use

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