Going Against Goliath 23 rd May 2010 Katrina Kurtz, MLIS Carrie Iwema, PhD, MLS Ansuman...

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Going Against Goliath 23 rd May 2010 Katrina Kurtz, MLIS Carrie Iwema, PhD, MLS Ansuman Chattopadhyay, PhD Health Sciences Library System University of Pittsburgh http://www.hsls.pitt.edu/guides/ge netics

Transcript of Going Against Goliath 23 rd May 2010 Katrina Kurtz, MLIS Carrie Iwema, PhD, MLS Ansuman...

Page 1: Going Against Goliath 23 rd May 2010 Katrina Kurtz, MLIS Carrie Iwema, PhD, MLS Ansuman Chattopadhyay, PhD Health Sciences Library System University of.

Going Against Goliath23rd May 2010

Katrina Kurtz, MLISCarrie Iwema, PhD, MLSAnsuman Chattopadhyay, PhDHealth Sciences Library SystemUniversity of Pittsburgh

http://www.hsls.pitt.edu/guides/genetics

Page 2: Going Against Goliath 23 rd May 2010 Katrina Kurtz, MLIS Carrie Iwema, PhD, MLS Ansuman Chattopadhyay, PhD Health Sciences Library System University of.

Photo credit: http://www.uncabaret.com/node?page=5

Page 3: Going Against Goliath 23 rd May 2010 Katrina Kurtz, MLIS Carrie Iwema, PhD, MLS Ansuman Chattopadhyay, PhD Health Sciences Library System University of.

Bioinformatics Tools

Answer biological questions

Made by informatics researchers

Freely available to the public

Published in scholarly journals

http://www.hsls.pitt.edu/guides/genetics

Page 4: Going Against Goliath 23 rd May 2010 Katrina Kurtz, MLIS Carrie Iwema, PhD, MLS Ansuman Chattopadhyay, PhD Health Sciences Library System University of.

Bioinformatics Tools

Examples: Protein structure prediction

Sequence alignment

Databases of genes associated with disease

Protein interactions

http://www.hsls.pitt.edu/guides/genetics

Page 5: Going Against Goliath 23 rd May 2010 Katrina Kurtz, MLIS Carrie Iwema, PhD, MLS Ansuman Chattopadhyay, PhD Health Sciences Library System University of.

Who Uses Bioinformatics Tools?

Biologists: Faculty researchers Graduate students Undergraduate students

Doctors who do biomedical research

Biomedical informatics researchers

http://www.hsls.pitt.edu/guides/genetics

Page 6: Going Against Goliath 23 rd May 2010 Katrina Kurtz, MLIS Carrie Iwema, PhD, MLS Ansuman Chattopadhyay, PhD Health Sciences Library System University of.

Online Bioinformatics Resources Collection Manually curated

Searchable collection of bioinformatics tools

Freely available to the public

2696 resources

http://www.hsls.pitt.edu/guides/genetics/obrc/

http://www.hsls.pitt.edu/guides/genetics

Page 7: Going Against Goliath 23 rd May 2010 Katrina Kurtz, MLIS Carrie Iwema, PhD, MLS Ansuman Chattopadhyay, PhD Health Sciences Library System University of.

http://www.hsls.pitt.edu/guides/genetics

Page 8: Going Against Goliath 23 rd May 2010 Katrina Kurtz, MLIS Carrie Iwema, PhD, MLS Ansuman Chattopadhyay, PhD Health Sciences Library System University of.

http://www.hsls.pitt.edu/guides/genetics

Page 9: Going Against Goliath 23 rd May 2010 Katrina Kurtz, MLIS Carrie Iwema, PhD, MLS Ansuman Chattopadhyay, PhD Health Sciences Library System University of.

http://www.hsls.pitt.edu/guides/genetics

Page 10: Going Against Goliath 23 rd May 2010 Katrina Kurtz, MLIS Carrie Iwema, PhD, MLS Ansuman Chattopadhyay, PhD Health Sciences Library System University of.

Common Criticisms…

Why bother?

Everyone uses Google.

Google is taking over.

http://www.hsls.pitt.edu/guides/genetics

Page 11: Going Against Goliath 23 rd May 2010 Katrina Kurtz, MLIS Carrie Iwema, PhD, MLS Ansuman Chattopadhyay, PhD Health Sciences Library System University of.

Is Google Actually Better?

http://www.hsls.pitt.edu/guides/genetics

Large amount of data

Popularity ranking

Biologists are not librarians

Page 12: Going Against Goliath 23 rd May 2010 Katrina Kurtz, MLIS Carrie Iwema, PhD, MLS Ansuman Chattopadhyay, PhD Health Sciences Library System University of.

Research Project Hypothesis

http://www.hsls.pitt.edu/guides/genetics

OBRC is better than Google at Locating bioinformatics tools

Quickly Easily Successfully

Leaving users happier with: Results Overall experience

Page 13: Going Against Goliath 23 rd May 2010 Katrina Kurtz, MLIS Carrie Iwema, PhD, MLS Ansuman Chattopadhyay, PhD Health Sciences Library System University of.

Research Project

http://www.hsls.pitt.edu/guides/genetics

10 biology graduate students

Three tasks on both OBRC and Google

Recorded search as they narrated

Search experience survey

Page 14: Going Against Goliath 23 rd May 2010 Katrina Kurtz, MLIS Carrie Iwema, PhD, MLS Ansuman Chattopadhyay, PhD Health Sciences Library System University of.

Research Project

Measured:

Time spent on each search Number of search queries Number of sites visited Success rate Users’ ratings

http://www.hsls.pitt.edu/guides/genetics

Page 15: Going Against Goliath 23 rd May 2010 Katrina Kurtz, MLIS Carrie Iwema, PhD, MLS Ansuman Chattopadhyay, PhD Health Sciences Library System University of.

Task 1: Protein Interaction

http://www.hsls.pitt.edu/guides/genetics

You are a pharmacologist interested in drugs that target proteins. Where would you find reliable information about how drugs interact with proteins, specifically information about the strength of the binding between the protein and ligand?

Page 16: Going Against Goliath 23 rd May 2010 Katrina Kurtz, MLIS Carrie Iwema, PhD, MLS Ansuman Chattopadhyay, PhD Health Sciences Library System University of.

Task 2: Structure Prediction

http://www.hsls.pitt.edu/guides/genetics

Find a tool that performs protein structure prediction. Determine from the search engine how often it has been cited.

Page 17: Going Against Goliath 23 rd May 2010 Katrina Kurtz, MLIS Carrie Iwema, PhD, MLS Ansuman Chattopadhyay, PhD Health Sciences Library System University of.

Task 3: Ovarian Cancer

http://www.hsls.pitt.edu/guides/genetics

Where would you look for information about all the published gene mutations implicated in ovarian cancer, in one place?

Page 18: Going Against Goliath 23 rd May 2010 Katrina Kurtz, MLIS Carrie Iwema, PhD, MLS Ansuman Chattopadhyay, PhD Health Sciences Library System University of.

Is it faster?

http://www.hsls.pitt.edu/guides/genetics

Task 1 Task 2 Task 3 Average0

50

100

150

200

250

300

350

Average Task Completion Time

GoogleOBRC

Tim

e (

s)

ProteinInteraction

StructurePrediction

Ovarian Cancer

Page 19: Going Against Goliath 23 rd May 2010 Katrina Kurtz, MLIS Carrie Iwema, PhD, MLS Ansuman Chattopadhyay, PhD Health Sciences Library System University of.

Is it easier to find results?

http://www.hsls.pitt.edu/guides/genetics

Task 1 Task 2 Task 3 Average0

1

2

3

4

Average Number of Search Queries

GoogleOBRC

Nu

mb

er

of

Qu

eri

es

ProteinInteraction

StructurePrediction

Ovarian Cancer

Page 20: Going Against Goliath 23 rd May 2010 Katrina Kurtz, MLIS Carrie Iwema, PhD, MLS Ansuman Chattopadhyay, PhD Health Sciences Library System University of.

Is it easier to find results?

http://www.hsls.pitt.edu/guides/genetics

Task 1 Task 2 Task 3 Average0

1

2

3

4

Number of Sites Visited Before Success

GoogleOBRC

Nu

mb

er

of

Sit

es

Vis

ite

d

ProteinInteraction

StructurePrediction

Ovarian Cancer

Page 21: Going Against Goliath 23 rd May 2010 Katrina Kurtz, MLIS Carrie Iwema, PhD, MLS Ansuman Chattopadhyay, PhD Health Sciences Library System University of.

Is it successful?

http://www.hsls.pitt.edu/guides/genetics

Task 1 Task 2 Task 3 Average0%

20%

40%

60%

80%

100%Rate of Success

GoogleOBRC

Pe

rce

nta

ge

of

Su

cc

es

sfu

l Se

arc

he

s

ProteinInteraction

StructurePrediction

Ovarian Cancer

Page 22: Going Against Goliath 23 rd May 2010 Katrina Kurtz, MLIS Carrie Iwema, PhD, MLS Ansuman Chattopadhyay, PhD Health Sciences Library System University of.

Do users like it?

http://www.hsls.pitt.edu/guides/genetics

Appropriateness of Results

Ease of Use Overall Experience1

2

3

4

5

6

7

Survey Results

GoogleOBRC

Ra

tin

g

Page 23: Going Against Goliath 23 rd May 2010 Katrina Kurtz, MLIS Carrie Iwema, PhD, MLS Ansuman Chattopadhyay, PhD Health Sciences Library System University of.

What do they say about Google?

http://www.hsls.pitt.edu/guides/genetics

“I was just frustrated [by Google].”

“Google was difficult to navigate with all the information on cancer.”

“[Google is] time consuming unless we know what we are searching for.”

“I realized that Google is not an

effective search tool.”

Page 24: Going Against Goliath 23 rd May 2010 Katrina Kurtz, MLIS Carrie Iwema, PhD, MLS Ansuman Chattopadhyay, PhD Health Sciences Library System University of.

What do they say about OBRC?

http://www.hsls.pitt.edu/guides/genetics

“Wow, this is really direct!”

“Gives good results, but I don’t like the interface.”

“OBRC is an excellent resource, especially if

you don’t know exactly what you’re

searching for.”

“[OBRC] was much easier to locate

relevant information.”

Page 25: Going Against Goliath 23 rd May 2010 Katrina Kurtz, MLIS Carrie Iwema, PhD, MLS Ansuman Chattopadhyay, PhD Health Sciences Library System University of.

What did we learn about OBRC? Time lag

Scopus and Google Scholar

Spell check

Long search queries

Unaware it exists

http://www.hsls.pitt.edu/guides/genetics

Page 26: Going Against Goliath 23 rd May 2010 Katrina Kurtz, MLIS Carrie Iwema, PhD, MLS Ansuman Chattopadhyay, PhD Health Sciences Library System University of.

Limitations

Small sample size

Potential bias from tasks

Previous experience with Google

http://www.hsls.pitt.edu/guides/genetics

Page 27: Going Against Goliath 23 rd May 2010 Katrina Kurtz, MLIS Carrie Iwema, PhD, MLS Ansuman Chattopadhyay, PhD Health Sciences Library System University of.

Future Work

Larger sample size

Other user groups

User-chosen task

http://www.hsls.pitt.edu/guides/genetics

Page 28: Going Against Goliath 23 rd May 2010 Katrina Kurtz, MLIS Carrie Iwema, PhD, MLS Ansuman Chattopadhyay, PhD Health Sciences Library System University of.

Conclusions…

http://www.hsls.pitt.edu/guides/genetics

Searches using OBRC are: Faster Easier More successful

Users are more satisfied.

Users plan to use OBRC in the future.

Page 29: Going Against Goliath 23 rd May 2010 Katrina Kurtz, MLIS Carrie Iwema, PhD, MLS Ansuman Chattopadhyay, PhD Health Sciences Library System University of.

Conclusions…

http://www.hsls.pitt.edu/guides/genetics

…libraries can and should

compete!

Page 30: Going Against Goliath 23 rd May 2010 Katrina Kurtz, MLIS Carrie Iwema, PhD, MLS Ansuman Chattopadhyay, PhD Health Sciences Library System University of.

http://www.hsls.pitt.edu/guides/genetics

This study is IRB approved. Funding provided by: NLM Grant 3 T15

LM007059-23S1 Thanks to my collaborators, Dr. Carrie Iwema

and Dr. Ansuman Chattopadhyay Special thanks to Nancy Tannery and Dr.

Rebecca Crowley

Page 31: Going Against Goliath 23 rd May 2010 Katrina Kurtz, MLIS Carrie Iwema, PhD, MLS Ansuman Chattopadhyay, PhD Health Sciences Library System University of.

Thank you!Any questions?

Katrina Kurtz Carrie Iwema Ansuman [email protected] [email protected] [email protected] 412-624-3508 412-648-6887 412-648-1297

http://www.hsls.pitt.edu/guides/genetics