Global Breast Cancer Burden | The Cancer...
Transcript of Global Breast Cancer Burden | The Cancer...
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“Canceratlas.cancer.org
Copyright © 2014 The American Cancer Society, Inc.Canceratlas.cancer.org Copyright © 2014 The American Cancer Society, Inc.
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Breast cancer incidence rates continue to increase in all countries except
a few high-income countries, while mortality rates are decreasing in many
high-income countries and increasing in low- and middle-income countries.
AGE-STANDARDIZED INCIDENCE AND MORTALITY RATES (WORLD) PER 100,000 FOR SELECT COUNTRIES, 1975-2011
76.3 or more No Data55.8 — 76.239.7 — 55.826.0 or less 26.01—39.6
Female Breast Cancer Mortality
ESTIMATED AGE-STANDARDIZED RATE
(WORLD) PER 100,000 POPULATION, 2012
20.8 or more No Data16.0 — 20.712.1 — 15.98.1 or less 8.2—12.0
12 THE BURDEN1 Breast cancer is the most common cancer
in women worldwide, with slightly more cases estimated in 2012 in less-developed (883,000 cases) than in more-developed (794,000) regions. Of the 184 countries included in the GLOBOCAN database, breast cancer is the most common cancer diagnosis in women in 140 countries (76%) and the most frequent cause of cancer mortality in 101 countries (55%). 3 Incidence rates vary nearly fourfold across the world regions, ranging from 27 per 100,000 in Middle Africa and Eastern Asia to 96 per 100,000 in Western Europe, and tend to be elevated in countries with highest development. Breast cancer is the most frequent cause of cancer death in women in less-developed regions (324,000 deaths, 14.3% of total) and the second cause of cancer death in more-developed regions (198,000 deaths, 15.4%), after lung cancer. 2 Incidence rates continue to increase in all countries except in a few high-income countries. In contrast, mortality rates are decreasing in many high-income countries but increasing in low- and middle-income countries.
BREAST CANCERBreast cancer is by far the most frequently diagnosed cancer and cause of cancer death among women worldwide.
“People used to say everyone knows someone who’s had breast cancer. In the
past few weeks, I’ve learned something else: Everyone has someone close to them who
has had breast cancer.”
— Debbie Wasserman Schultz, US House of Representatives,
breast cancer survivor
Although the estimated number of breast cancer deaths is less than a third of estimated new cases, breast cancer is the most
common cause of cancer death in women in less-developed countries, and the second among women in developed countries.
ESTIMATED NEW BREAST CANCER CASES AND DEATHS BY REGION, 2012
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There were an estimated 1.7 million new cases (25% of all cancers in women) and 0.5 million cancer deaths (15% of all cancer deaths in women) in 2012.
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High-income
Lower middle income
Australia
Denmark
India
Japan
The variation in mortality rates between world regions (ranging from 6 per 100,000 in Eastern Asia to 20 per 100,000 in Western Africa) is less than that for incidence rates because of the considerably better survival from breast cancer in developed regions, resulting from increased access to early detection (mammography) and treatment. Differences in incidence between countries with and without mammography screening programs are also influenced by earlier diagnosis and the overdiagnosis associated with detecting breast cancers in asymptomatic women. Overall, a substantially greater proportion of women with breast cancer will die from their disease in less-developed regions.
TOTAL ESTIMATED CASES
1,700,000TOTAL ESTIMATED DEATHS
522,000
India
China
Other East & Central Asia
Europe
Northern America
Latin America & Caribbean
Sub-Saharan Africa
Middle East & North Africa
Oceania
| | | |1980 1990 2000 2010
| | | |1980 1990 2000 2010
INCIDENCE
120—
100—
80—
60—
40—
20—
RAT
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10
0,0
00
Australia
Denmark
Guatemala
Israel
MORTALITY
30—
25—
20—
15—
10—
5—
RAT
E P
ER
10
0,0
00
Sub-Saharan Africa
Middle East & North Africa
Europe
Oceania
Northern America
East & Central Asia
Latin America & the Caribbean
India
China
17.216.216.115.614.813.7
1312.75.4
Although incidence rates are highest in developed regions,
mortality rates in these areas are comparable
to most of the less-developed regions.
ESTIMATED AGE-STANDARDIZED FEMALE BREAST CANCER INCIDENCE RATE (WORLD) PER 100,000, 2012
Northern America
Oceania
Europe
Latin America & the Caribbean
Middle East & North Africa
East & Central Asia
Sub-Saharan Africa
India
China
91.679.271.147.243.038.333.825.822.1
Female Breast Cancer Incidence
ESTIMATED AGE-STANDARDIZED RATE
(WORLD) PER 100,000 POPULATION, 2012
ESTIMATED AGE-STANDARDIZED FEMALE BREAST CANCER MORTALITY RATE (WORLD) PER 100,000, 2012
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