Packaging Technology

GKF 2600the flexible capsule filling platform

2|GKF 2600 the flexible capsule filling platform

Your advantages at a glance Proven machine technology Versatile filling options Flexible use for different

products Simple operation via HMI Fast and easy modification More than 50 years of

experience in capsule filling

One platformfor all requirementsYou want to fill your products into capsules flexibly and reliably? Then the modular machine platform of the GKF 2600 series is your ideal solution. Due to its flexibility and inspection technologies the capsule filling machine can be tailored to your products and requirements within next to no time.

During the development of the new GKF 2600 series we focused particularly on your require-ments. The result is a highly flexible machine platform. It features interfaces and drives that

are compatible with all filling stations. This way you can optimally process different products with changing parameters at an output of up to 2,600 capsules per minute.

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With the GKF 2600 you receive a compact capsule filling machine in the high-performance range. Based on many years of experience we have designed a future-proof platform that consistently adapts to your production requirements. The cGMP compliant machine meets all demands for the highest pharmaceutical safety.

The GKF 2600 offers you numerous technical advantages. Its flexible machine platform combines highest ergonomics, easy operation and cleaning, as well as safe processing for best capsule filling results.

Technical characteristics at a glance Good accessibility from all sides Different types of capsule body scanner

depending on the equipment used No body no fill / No cap no fill

on all filling stations Control cabinet separable for technical

room on demand

During the development of our machines we attach particular importance to offering you economic solutions. The GKF 2600 is a compact machine platform that achieves precise results and keeps product loss to a minimum.

Your economic advantages One compact platform as basis Output of up to 2,600 capsules per minute Optimized faulty capsule discharge Low-maintenance operation

Optimized faulty capsule discharge

Combinations and special solutions

Tablets (micro and macro)

Liquids

Powder and micro dosing

Pellets

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Filling technologies and dosing optionsat a glance

The GKF 2600 doses powders, pellets, tablets and liquids, as well as combinations reliably and precisely. Depending on your wishes, the platform can also meet your specific requirements.

Functional discription

Capsule alignment and separation

Capsule alignment and separation

IPK and capsule body scanner, or capsule cap and body scanner

Capsule cap scanner (with IPK), or tablet/pellet station (with optional capacitive weighing)

Dosing station for powder or pellets with fixed or height-adjustable dosing disc, liquid station or micro dosing station (with optional capacitive weighing)

Free position optional tablet or pellet station (with optional capacitive weighing)

Faulty capsule discharge

Free position optional tablet or pellet station (with optional capacitive weighing)

Capsule closing station with presence verification of capsule cap and body

Individual capsule discharge Option: x-ray control

Individual capsule discharge Option: x-ray control

Segment cleaning with compressed airOption: sampling (if no IPK)

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Equipped with the respective filling station, the GKF 2600 series achieves precise filling results for pasty to sticky powders, as well as for liquid products. We will be happy to develop an individual solution for your products and product combinations regardless of their flow properties.

Powder/pelletsThe dosing station with patented slidegate technology is suited for filling powders or pellets. While the proven tamping pin principle is used for powder, pellets are filled via a fixed or height-adjustable dosing disc.

Micro dosingHighly precise dosing of smallest quantities via dosing wheel, e.g. for inhalation products.

Pellets The pellet station offers gentle filling and is also available as height- adjustable version.

(Micro) TabletsThe tablet station enables you to precisely fill a defined number of tablets.

LiquidsFrom waxy to liquid products the liquid pump with integrated drip protection ensures reliable and precise filling operations.

CombinationsThanks to its modular design the GKF 2600 is suited for a large number of multiple combinations.

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Precise and reliable fillingModular options for the highest product quality

The GKF 2600 can be flexibly equipped with checkweighing and inspection modules. This way you receive precisely filled capsules and can eliminate faulty products. Thanks to the early identification of defects or wrongly filled capsules you can reduce product loss to a minimum.

Integrated IPK Integrated in-process control (IPK) Gross and net weight determination Target/actual comparison according

to interval-based samples Feedback loop for automatic dosing adjustment Also available for liquid station

KKE 2600 checkweigher Precise 100% weighing

of all capsules Integrated automatic trouble

shooting (ASB) Automatic discharge of

deformed capsules Seamless documentation of

production data Easy and fast cleaning

Net Weight Detection System (NWDS)Correction of differences in filling volumesFor micro dosingFor pellet filling

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X-ray inspection technology as stand-alone unit or integrated into GKF

Safety is top priority for products and operatorsThe KKX 3900 is based on x-ray technology. According to an independent study, x-radiation has no impact on light-sensitive active ingredients.

The inspection unit is designed for 100% weight and quality control of filled capsules. The KKX 3900 as stand-alone version can be optimally combined with the GKF 2600. Alternatively you receive an integrated system*, where the in-process control based on x-ray technology takes place within the GKF 2600. Profit from the simultaneous inspection of all quality features for highly efficient results.

The radiation dose is approx. 5,000 times lower than the German pharmaceuticals regulation permits. The control unit itself is designed as full-protection device, so that operating staff is not exposed to any health impairments.

Your advantages at a glance Inspection of up to

220,000 capsules per hour Identification of process

relevant data in real time Precise weight measurement Detection of foreign matters Length control Identification of deformed

capsules Including batch documentation

The KKX 3900 inspects all quality parameters efficiently and reliably

Integrated solution*

*available as of 2016

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GKF 2600 the future-proof capsule filling machineAdaptable to all future requirements

Our long-term experience and competence in capsule filling make it possible: the GKF 2600 is based on tried and tested technologies and can be retrofitted and modified according to your requirements. This makes your GKF 2600 a future-proof investment expandable by highly modern options and technologies.

Easy retrofitting thanks to modular design Machine platform also combinable

with future solutions Future and investment-proof solution Compatible with format parts of GKF 2500 Format change times reduced by 50%

thanks to easy plug-in system

Are your production conditions changing, or do you need an update of your current capsule filling technology? No problem! With the GKF 2600 you receive a platform that is suited for modular extension and upgrades entirely according to your wishes and requirements.

Proven technology equipped for all future requirements

The formats of the GKF 2500 can also be used on the GKF 2600 with minimal adaptations, and are thus suited for both machines.

Segments and dosing disc of the GKF 2500

Segments and dosing disc of the GKF 2600

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Containmentfor a safe production

The GKF 2600 offers you, your staff and your products the highest protection. The capsule filling machine is characterized by a very safe and reliable design, and can be flexibly adapted to containment requirements.

Standard versions Robust and tight doors with safe sealing Reduced dust formation thanks

to optimized dust suction No body no fill / No cap no fill system Mechanical discharge of faulty capsules

without compressed air Easy cleaning concept

Containment upgrade Same basis including drives Easy exchange of upper machine unit Negative pressure system High OEB level up to OEB 4

Safety is top priority in pharmaceutical production especially when you are using highly potent substances in your production processes. A reliable containment system minimizes the contact of active ingredients and operators significantly.

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Line competenceMore than just a machine: Bosch provides complete line concepts, tailored exactly to your requirements and designed to meet your individual needs. As your competent partner we offer detailed project and integration competence, as well as comprehensive qualification and validation, backed by extensive after-sales services such as training programs.

GKF 2600 and KKE 2600: the ideal double for capsule filling and weighing

KKX 3900: reliable quality control for capsules

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Technical details at a glance

Output Max. 156,600 capsules per hour

Depending upon in-feed, quality and flow properties of the product

Segment bores 18

Capsule types Hard gelatin capsules, HPMC capsules

Formats Capsule sizes 00 to 5, DB

Capacity of dosing systems Dosing disc (powder, granulate, pellets)

up to 145 cycles/min | 156,600 capsules/h Pellet station

up to 145 cycles/min | 156,600 capsules/h Tablet station

up to 120 cycles/min | 129,600 capsules/h Liquid station

up to 100 cycles/min | 108,000 capsules/h Micro dosing station

up to 140 cycles/min | 150,000 capsules/h

Filling range micro dosing 150 mg

Filling volume From 1 mm3

In-feed systems Powder in-feed

Triclamp DN 150 DIN, 32676 Pellet/tablet in-feed

Triclamp DN 100 DIN, 32676 Empty capsule in-feed

Triclamp DN 100 DIN, 32676

Connections Compressed air supply 13 mm Connection vacuum

30 mm Connection dust collector

2 x 70 mm Socket for vacuum pump Socket for tip cable Socket for dust collector Electrical main connection

Electrical connection machine 380480 V, 50/60 Hz, 3 PH/PE, 16 KVA

Other voltages possible

Weight Max. approx. 2,000 kg

Electrical connection dust collector 200/220/380/400 V, 50 Hz, 2x4 kW

220/380/400/460/480 V, 60 Hz, 2 x 4,6 kW

Conveying volume dust collector 820 m3/h, free suction

Compressed air demand From 0.5 (m3/h at 5 bar)

Vacuum demand Approx. 50 (m3/h at 250 bar)

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Integrated control cabinet Separate control cabinet in technical room

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Robert Bosch GmbH Packaging Technology Product Division Pharma Solid

Stuttgarter Strae 130 71332 Waiblingen Germany Phone +49 711 811-0 www.boschpackaging.com packaging-ph@bosch.com

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