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Product Catalogue 2019

Givaudan

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Product INCI Features in-vitro & ex-vivo in-vivoPreser- vatives

Use level Solubility

AGEFINITY

Glycerin (and) Water (and) Sodium Mannose Phos-phate (and) Mannose

The 3D Y reshaper, Anti-Aging

Reactivating mitochondrial energy metabolism (action on mitochondrial target and biogenesis) - No Negative impact on protein glycation - skin matrix restructuration ( Transcriptomic, Proteo-mic and morphological analysis, collagen fibers organisation) - control of protein ageing Increase of proteasome activity - reduction of oxidised proteins

Visible reduction of age spots (4 %; D28;D54), Improvement of skin collagen organisa-tion (4 %;D28;D54), Anti-wrinkle efficacy (D28;D56), Reduction of neck wrinkles (4 %;D28;D54)

Preserva-tive free

0.1 - 0.4 %

Hydrosoluble

BLURHD CQ U/A

Dipropylene Glycol (and) Gardenia Florida Fruit Extract

Reduces crow’s feet wrinkles, Stimu-lates the ceramide synthesis, Smoothes the skin

Oxygen Radical Absorbance Capacity (ORAC), Stimulation of BCL2-gene ex-pression limiting apoptosis, Stimulation of Ceramide synthesis (ex-vivo)

Anti-wrinkle effect on crow’s feet (4 %, D28), Smoothing of cutaneous relief and anti-wrinkle effect (2 %, D56)

None 0.1 - 4 %

Hydrosoluble

COSTALANE Caprylic/Capric Triglyce-ride (and) Skeletonema Costatum Extract

Poly-unsaturated fatty acid rich in omega-3, Restoration of skin homeostasis

Increase of GAP junction number, Promotes epidermal differentiation by increase of connexin 43 level

None 0.1 - 0.3 %

Lipoosoluble

EASYLIANCE 2.0

Acacia Senegal Gum (and) Hydrolyzed Rhizobian Gum

Smoothing, Impro-vement of micro relief, Immediate anti-wrinkle

Immediate wrinkle reduction (3 %, 5 min)

None 2 - 3 %

Hydrosoluble

Cosmos approved potentially NaTrue Vegan suitable CHINA approved Halal

ANTI-AGING

BODY SCULPTING

COOLING / OTHERS

HAIR AND BODY CARE

HYALURONIC ACID

MOISTURIZING

SKIN COMPLEXION

SKIN PROTEC TION

2 – 4

5

6

7 – 8

9 – 11

12

12 – 13

14 – 15

INDEX / APPLICATIONS

ANTI-AGING

2



ELLAGI-C

Propanediol (and) Anogeissus Leiocarpa Bark Extract

Anti-aging, Anti-wrinkle

Stimulation of vitamin C incorporation, Anti-MMPs, Antioxidant activity

Decrease of wrinkle depth (2 %, D14)

None 1 - 2 %

Hydrosoluble

HYALUSPHERE PF *Spherulite ®

Aqua (and) Sucrose Pal-mitate (and) Tocopheryl Acetate (and) Glyceryl Linoleate (and) Sodium Hyaluronate (and) Pheno-xyethanol (and) Potassium Sorbate (and) Citric Acid

Vectorized (Sphe-rulites technology) hyaluronic acid to recover skin's volume and reduce wrinkles in a very short term

Penetration test by Raman micro-ima-ging (ex-vivo), Visualisation of the incor-poration of Hyalusphere in emulsions

Decrease of average wrinkle number (3 %, 1h, 6h)

Phen-oxye-thanol, Potas-sium sorbate

2 - 3 %

Hydrodisper-sible

HYALUSPHERE XP *Spherulite ®

Aqua (and) Sucrose Pal-mitate (and) Tocopheryl Acetate (and) Glyceryl Linoleate (and) Sodium Hyaluronate (and) Benzyl Alcohol (and) Potassium Sorbate (and) Citric Acid

Vectorized (Sphe-rulites technology) hyaluronic acid to recover skin's volume and reduce wrinkles in a very short term

Penetration test by Raman micro-ima-ging (ex-vivo), Visualisation of the incor-poration of Hyalusphere in emulsions

Decrease of average wrinkle number (3 %, 1h, 6h)

Benzyl alcohol, Potas-sium sorbate

2 - 3 %

Hydrodisper-sible

HYDREIS

Aqua (and) Hydrolyzed Beta-Glucan (and) Sodium Benzoate (and) Potassium Sorbate (and) Citric Acid

3 in 1 active for skin rehydration, restruc-ture and repair

Stimulation of the synthesis of filaggrin, Stimulation of the synthesis of aquapo-rin, Restoration of the skin's structure and water homeostasis (ex-vivo), Restoration of the skin's structure with filaggrin (ex-vivo), Restoration of hydric homeostasis with AQP-3 (ex-vivo)

Reparative effect on barrier function (1 %, D3)

Sodium benzoate, Potas-sium sorbate

1 %

Hydrosoluble

MEGASSANE

Caprylic/Capric Trigliceride (and) Phaeodactylum Tricornutum (and) Tocopherol

Phytoplancton extract rich in ome-ga-3, Cell protection from UV, Prevention from photo-aging and age-spots

Repairing and protection of proteins from UV damage, Revitalization, Detoxification (Lit), Anti age spots (Lit), DNA repair (Lit)

None 0.1 - 0.3 %

Liposoluble

REDENS'IN *Spherulite ®

Sucrose Palmitate (and) Aqua (and) Caprylic/Capric Triglyceride (and) Glyceryl Linoleate (and) Commiphora Mukul Resin Extract (and) Sodium Hy-aluronate (and) Tocopherol (and) Citric Acid (and) Phenoxyethanol (and) Potassium Sorbate

A dermis and hypo-dermis voluminizing ingredient and high molecular weight hyaluronic acid encapsulated in Spherulites, Plum-ping, Anti-wrinkle

Skin is subject to ECM and adipose tissue age-related alterations (2 %)

Pheno-xyethanol

1.5 - 2 %

Hydrodisper-sible

REVIVYL

COSMOS certifica-tion on-going

Propanediol (and) Oro-banche Rapum Extract

Holistic skin renewal accelerator

Maintaining of the capability of skin stem cells to replicate themselves, Increase of expression of survivin after UV exposure, Inhibition of caspase 9 and caspase 3, Stimulation of epidermis metabolism (ex-vivo), Stimulation of keratinocytes differentiation and barrier function, Improvement of epidermal differentiation and barrier function (ex-vivo), Stimula-tion of the skin barrier components pro-duction (ex-vivo), Biological reactivation of natural exfoliation (ex-vivo)

Skin barrier reinforcement and hydration (Raman), (0.5 %, D14, D28), Skin epidermis restructuration (OCT), (0.5 %, D14, D28), Increase of skin surface renewal, exfoliation (Diagnoskin), (0.5 %, D7, D28), Maintenance of the stra-tum microbium (0.5 %, D14), Anti-aging effect (crwo's feet wrinkles), (0.5 %, D28)

None 0.1 - 0.5 %

Hydrosoluble

Cosmos approved Vegan suitable CHINA approved Halal

ANTI-AGING

3




SOFTALIA CQ U/A

Fusanus Spicatus Kernel oil

Sustainable Austra-lian sandalwood nut oil, Firm and supple skin, Reduction of fine wrinkles

Improvement of skin condition on face ("reduction in lines", "more moist/supple", "reduction in flakiness"), neck ("skin tightness", "reduction in wrinkles,/lines", "more moist/supple") and hands ("much tighter", "more moist/supple") (5 %; D90 Panelist's evaluation), Enhancement of sensorial benefits of cream formulation (2 %)

None 0.5 - 5 %

Liposoluble

SPHERULITE R10

Water (and) Cetearyl Alcohol (and) Retinol (and) Polysorbate 20

Microencapsulated stabilised retinol

Enhanced skin penetration (1.5 %) evaluated with Raman spectroscopy

Anti-aging effect on crow’s feet (2 %; D28; D54), Anti-wrinkle effect on nasolabial wrinkles (2 %; D28; D54), "Encapsulated Retinol has a visible effect on wrinkles and skin is more plumped" (2 %; Panelist´s evaluation)

Pheno-xyethanol (and) Ethylhe-xylgly-cerin

0.1 - 3 %

Hydrosoluble

SPRING SEA WATER

Maris Aqua (and) Pheno-xyethanol

Spring sea Water enriched in essential trace elements taking a unique composition

Stimulation of skin lipid synthesis, Dermo epidermal junction reinforcement, Skin moisturisation compared to classic water (ex-vivo)

Pheno-xyethanol

20 - 100 %

Hydrosoluble

STIMULHYAL

Calcium Ketogluconate Anti-aging effect by increasing natural production of hyalu-ronic acid

Elastin synthesis, Hyaluronic acid synthesis, Increase of hyaluronic acid synthesis (ex-vivo), Interaction with CD 44 (in silico test), Increase in CD 44 by immunolabelling (ex-vivo)

Skin elasticity (D28, 0.5 %), Anti-skin fatigue (D28, 0.5 %)

None 0.3 - 0.5 %

Hydrosoluble

VETIVYNE

Vetiveria Zizanoides Root Extract (and) Propanediol (and) Water

Anti-Aging, Anti-Wrinkles, Moisturi-zing, Regenerating, Stimulation of sebum production, stimulation of sebum antimicrobial lipids production, Activa-tion of adipocytes volume increase, Skin hydration, Skin fatigue reduction, Perilabial wrinkles reduction, Skin repulping, Fragrance long-lastingness enhancer

Lipid Stimulation at three levels, redifini-tion of volume adipocytes differentiation and size, keratinisation lipid synthesis and transport cornified envelope prote-ins, Sebum production lipids quantity and quality

90 volunteers, 45-65 y.old, application 2x day on face, (2 %, D21, D56) Reduction of forehead and crow's feet wrinkles, nasola-bial folds and improvement of skin firmness

None 1 - 3 %

Hydrosoluble

VITASPHERES E XP

Aqua (and) Sucrose Pal-mitate (and) Tocopheryl Acetate (and) Glyceryl Linoleate (and) Benzyl Alcohol (and) Potassium Sorbate (and) Citric Acid

Vitamin E encapsula-ted in Spherulites for improved penetration

Potas-sium sorbate, citric acid

5 - 15 %

Hydrosoluble

ANTI-AGING

4




ABDOLIANCE

Sucrose Palmitate (and) Polysorbate 20 (and) Glyceryl Linoleate (and) Paullinia Cupana Seed Extract (and) Maltodextrin (and) Prunus Amygdalus Dulcis (Sweet Almond) Oil (and) Lecithin (and) Aqua (and) Citrus Aurantium Amara (Bitter Orange) Peel Extract (and) Phenoxyethanol (and) Tocopherol

Waist slimming for men

Waist size reduction (2 %, D28), Reduction of hypoder-mis thickness (3 %, D28)

Pheno-xyethanol

1 - 3 %

Hydrodisper-sible

ACTISCULPT CQ U/A

Dipropylene Glycol (and) Commiphora Mukul Resin Extract (and) Coleus Forskohlii Root Extract

Herbal firming Increase of cAMP level in adipocytes

Thigh reduction and skin surface smoothing (1 %, D28, D56)

None 1 %

Liposoluble

COMMIPHE-ROLINE

Caprylic/Capric Triglyce-ride (and) Commiphora Mukul Resin Extract

Skin tonifier, Wrinkle filler, Breast and décolleté care

G3PDH activation (effects on lipoge-nesis), cAMP inhibition (effects on lipoly-sis), Increase of triglyceride quantity in adipocytes

None Anti-aging: 0.2 - 0.6 %

Bodycare: 0.5 - 1 %

Liposoluble

PRO-DG

Aqua (and) Plankton Extract (and) Sodium Benzoate (and) Potassium Sorbate (and) Citric Acid

Marine origin slim-ming to reduce the tigh-size

Inhibition of triglycerides synthesis, Stimulation of cAMP rate, Stimulation of lipolyse (in-vitro & ex-vivo) Reduction of the adipocytesdiameter (ex-vivo)

Reduction of thighs size (3 %, D28, D56)

Sodium benzoate, Potas-sium sorbate

3 %

Hydrosoluble

BODY SCULPTING

5

Cosmos approved potentially NaTrue Vegan suitable CHINA approved



DIAMOND

Diamond Powder Stimulates cutaneous microcirculation, Improves skin com-plexion, Energyzing, Granulometry: < 15μ

Improvement of skin regeneration, Stimulation of immuno reactions (Lit)

None 0.5 - 2 %

Oil disper-sible

EVERCOOL SKIN

Menthyl PCA (and) Lactamide MEA (and) Menthane Carboxamide Ethylpyridine

Patented combination of Givaudan cooling actives, Impro-ved long-lasting freshness, Odourless cooling agent

Activation of cooling sensation receptor TRMP8

Long lasting cooling effect (2 %, 30 min, 60 min, 120 min)

None 1 - 4 %

Hydrosoluble and soluble in alcohol

QUESTICE LIQUID CQ U/A

Menthyl PCA Long-lasting perception of cooling and additional moisturizing effect

Underarm cooling panel test with deodorant spray (1.7 %), Long-lasting effect of Questice® vs. Menthol with no burning sensation (1 %), Synergistic effect of Questice® Plus with increased initial ‘cooling burst’ (1.2 % Que-stice® Plus,1 % Questice®)

None 0.5 - 1.5 %


QUESTICE PLUS CQ U/A

Menthyl PCA (and) Men-thol (and) Dipropylene Glycol

Immediate and long-lasting perception of cooling composed of 1 % Questice® Liq + 0.2 % free Menthol

Underarm cooling panel test with deodorant spray (1.7 %), Long-lasting effect of Questice® vs. Menthol with no burning sensation (1 %), Synergistic effect of Questice® Plus with increased initial ‘cooling burst’ (1.2 % Que-stice® Plus) (1 % Questice®)

None 1 - 2 %


SOLIGEL

Rhizobian Gum Anti-dark circle under the eyes, Anti-redness, Rheology modifier, Improves sensory characte-ristics of cosmetic formulations

Immediate reduction of dark rings (2 %), Improvement of sensorial properties of the formula (0.25 % alone or with salt), Flash moisturizing (2 %)

None 0.1 - 2 %

Hydrosoluble

COOLING / OTHERS

6

Vegan suitable CHINA approved Halal



CERAMIDE II CQ U/A

Ceramide NG Skin moisturizer, Li-pid barrier rebuilder, Hair strengthener & conditioner

Deposition onto hair (ex-vivo), Evaluation of hair softness (ex-vivo), Hair strengthe-ning effect (ex-vivo, 1 %)

Reduction of TEWL (2 %, D26) None 0.05 - 1 %

Liposoluble

DARKENYL

Glycerin (and) Water (and) N-Acetyl-Tyrosine (and) Sodium Metabisulfite (and) Glycine (and) Larix Europaea Wood Extract (and) Zinc Chloride (and) Camellia Sinensis Leaf Extract

Hair pigmentation recovery, Decrease-ment of grey / white hair density

Stimulation of stem cells related genes (50μM taxifolin glucoside=1 % Darkenyl™) Stimulation of hair follicle stem cells (0.04 % taxifolin glucoside=1 % Darkenyl™), Stimulation of melanogenesis (0.01 %), Activation of hair follicles defences and pigmentation (1 %) (ex-vivo), Protection of melanocytes against oxidative stress (1 %) (ex-vivo), Stimulation of melanin production in greying hair (1 %) (ex-vivo)

White hair proportion and density reduction (44 Caucasian male volun-teers, 18 years+, with white hair, 4 months, in leave-on formulation,1 %)

Sodium Metabi-sulfite

0.1 - 1 %

Hydrosoluble

GLOSSYLIANCE

Aqua (and) Lactic Acid (and) Citrus Limon Peel Extract (and) Saccharum Officinarum Extract (and) Malic Acid (and) Citric Acid

Increases hair shine, Visible effect of softness of the hair

Increased shine (ex-vivo), Increased softness (ex-vivo)

Increased shine, Increased softness (1 %, 3 %, 5 %, D14)

None 3 %

Hydrosoluble

HAIRSPHERE AG XP *Spherulite ®

Aqua (and) Polyglyceryl-3 Distearate (and) Polysor-bate 60 (and) Myristic Acid (and) Stearic Acid (and) Palmitic Acid (and) Guar Hydroxypropyltrimo-nium Chloride (and) Triti-cum Vulgare Flour Lipids (and) Persea Gratissima Oil (and) Benzyl Alcohol (and) Potassium Sorbate (and) Citric Acid

Vectorized (Sphe-rulites technology) fatty acids, avocado oil and ceramids; an ideal mixture of active ingredients for hair nourishment


0.05 - 3 %

Hydrodisper-sible

RESISTHYAL

Water (and) Sodium Hyaluronate (and) Hydrolyzed Hyaluronic Acid (and) Phenoxyethanol (and) Lactic Acid

Hair beauty enhancer Sheathing effect around hair fibre (ex-vivo), Biological hydration of hair fibre (ex-vivo), Resistance to mechanical and thermal stresses (ex-vivo), Resistance to dullness, Increased shininess (ex-vivo), Resistance to frizzing, hair straightening enhancement (ex-vivo), Resistance to pollution, Anti-adhesion properties (ex-vivo)

Global hair beauty enhance-ment in a rinse off formulation (3 %, D14, D28), "Increased perception of the hair beauty parameters" (shininess, lightness, easiness to comb, natural volume, resistance, revitalise, increased body and matter, smoothesness, soft-ness, suppleness) (1.5 %, 3 %, D28) (panelist's evaluation), Anti-frizz and resistance to humidity (3 %, single use), Beauty enhancement in a rinse-off formulation (1.5 %, 3 %, D28)

Pheno-xyethanol

1.5 - 3 %

Hydrosoluble

HAIR AND BODY CARE

7




SINODOR CQ U/A

Citronellyl Methylcro-tonate

Odour control agent, Captures and neu-tralizes unpleasant odours

Reduction of all types of body malodours, Reduction of fatty acid malo-dours of formula bases (1 %), Reduction of odor emitted by permanent waves (ex-vivo), Reduction of smoke odour on hair (ex-vivo)

None 0.2 - 1 %

Liposoluble

SOFTOLIVE

Hydrogenated Ethylhexyl Olivate (and) Hydrogena-ted Olive Oil Unsaponi-fiables

Very dry olive-based emollient, Excellent penetration and skin feel for skin, Sun and hair care

None 2 - 10 %

Liposoluble

YOGURTENE BALANCE CQ (PFR) U/A

Inulin (and) Yogurt Powder

Prebiotic efficacy, Promotes to balance skin flora by anti-bacterial effect, Skin moisturizing

Strong reduction of S. aureus and E. coli species present on the skin

None 0.5 - 5 %

Hydrosoluble

YOGURTENE IO

Yogurt Powder Skin firming proper-ties, Hair conditioner, Lather booster

Stimulation of collagen latice concen-tration

Improves quality of dry hair, combability of wet hair and defines curles (0.2 % in combing cream), Hair style holding and anti-fly-away (1 %), Perceivable improve-ment of soap foam density and creaminess (0.5 %)

None 0.5 - 5 %

Hydrosoluble

HAIR AND BODY CARE

8




CRISTALHYAL

Sodium Hyaluronate Moisturization by film forming and water retention, Eye contour care; MW 1-1.4 MDa

Skin moisturization (Raman Spectrosco-py) (ex-vivo), Prevention and calming of inflammation, Protection against UVB

Long-lasting moisturization upto 24hrs (0.1 %, 8h, 24h)

None 0.01 - 0.3 %

Hydrosoluble

PRIMALHYAL 300

Hydrolyzed Hyaluronic Acid

Hyaluronic acid with mid-range MW 100-300 kDa, Stimulation of the skin natural defense system

Increase of beta-defensine release, especially DEFB2 (in-vitro, ex-vivo), Sti-mulation of DEFB4 gene expression, Inhi-bition of gram negative bacteria activity (ex-vivo), Stimulation of keratinocytes migration and fibroblasts prolieferation (support of wound healing), Migration and proliferation of the fibroblasts, Penetration in the skin (ex-vivo)

None 0.05 - 0.2 %

Hydrosoluble

PRIMALHYAL 3K


PrimalHyal 3K is a mix of 3 Hyaluronic Acids (HA): - Primalhyal 300 (100-300 kDa) to reinforce the skin natural defense and wound healing process, - Primalhyal 50 (20-50 kDa) to improve skin biome-chanical properties and firmness, - Primalhyal 20 (5-20 kDa) to rejuvenate the dermis from inside

Stimulation of tight junction protein synthesis, Stimulation of DEFB2 release (in-vitro and ex-vivo), Antimicrobial activity, Specific healing activity, Stimu-lation of procollagen I, Improvement of HA synthesis

Improvement of skin biome-chanical properties (0.5 %, D56, 20-50 kDa HA)

None 0.1 - 1 %

Hydrosoluble

PRIMALHYAL 50


Hyaluronic acid with very low MW (20-50 kDa) Reduction of TEWL (patent) Collagen-boosting effect, Skin hydro-retention, Improves skin tonicity

Stimulation of tight junction protein synthesis, Stimulation of procollagen I

Moisturization (0.5 %, D28), "Skin is more moisturized, skin is more tonic, skin is firmer" (0.5 %, D28; Panelist's evaluation)

None 0.1 - 0.5 %

Hydrosoluble

PRIMALHYAL GOLD

PEG-8 Caprylic/Capric Gly-cerides (and) Water (and) Octyldodeceth-25 (and) Sodium Hyaluronate

Oilsoluble hyaluronic acid for longterm hydration, make-up care, lip products

Skin penetration (ex-vivo), Instant and long lasting hydration benefits (ex-vivo; total water content T+30 min vs T+8h +13 %; +45 % vs T0; free water content T+30 min vs T+8h +14 %; +50 % vs T0)

Phen-oxye-thanol, Decylene glycol, Propylene glycol

4 - 5 %

Liposoluble

HYALURONIC ACID

9




PRIMALHYAL ULTRAFILLER

Sodium Acetylated Hyaluronate

Fast wrinkle reduction, Skin texture improvement, Nasogenian wrinkles reduction and filler, Crow’s feet wrinkles filler, Antioxidant defences booster, Photo-pollution protector

Deeper skin penetration (1 %); Resistance to Hyaluronidase; Multifunctional: antioxidant, antipol-lutant and anti ageing (0.01 %, 0.1 %) Antioxidant activity: increase the expres-sion of thioredoxin reductase in oxidative stress conditions (0.1 %); Antipollution activity (0.1 %); Anti-ageing activity: Protection of the extracellular matrix by decreasing MMP-1 and MMP-3 collagenases production and collagen I degradation, even under photo pollution (0.1 %)

1. Clinical study: 20 women, average age 56 with wrinkles in the nasolabial area, (D28, application 2x day, 0.1 %) vs.placebo Wrinkel reduction from the nesogenian area 2. Clinical study: 20 women, average age 47 (D56, applica-tion 2x day, 0.1 %) vs.placebo (2 % Vitamin E Acetate) Reduction of UV induced lipid peroxidation and restoration of skin antioxidant capacities. 3. Clinical study: 30 women, average age 57 (D56, applica-tion 2x day, 0.1 %) vs.placebo Reduction of skin granulosity/roughness 4. Clinical study: 21 women, average age 63 (1h, 6h, 0.2 %) vs.placebo Reduction of crow’s feet number, wrinkle depth and length

None 0.1 - 0.2 %

Hydrosoluble

RENOVHYAL

Sodium Hyaluronate Hyaluronic acid with very low MW (20-50 kDa), Reduction of TEWL (patent), Collagen-boosting effect, Skin hydro-retention, Improves skin tonicity

Stimulation of tight junction protein synthesis, Stimulation of procollagen I

Moisturization (0.5 %, D28), "Skin is more moisturized, skin is more tonic, skin is firmer" (0.5 %, D28; Panelist's evaluation)

None 0.1 - 0.5 %

Hydrosoluble

HYALURONIC ACID

10

2‘200

2‘000

1‘800

1‘000

700

500

300

100

1‘400

50

20

5

Very low

Low

Average

Very high

High

Molecular weight kDa Powder form Coupling

Cutaneous permeability of HA

PrimalHyal 10<10 kDa

PrimalHyal 20 5 - 20 kDa

PrimalHyal 50 Renovhyal20 - 50 kDa

PrimalHyal 300 Bashyal Powder

100 - 300 kDa

Cristalhyal 1.0PrimalHyal 1000 700 - 1000 kDa

Cristalhyal 1 - 1.4 MDa

Hyalusphere XP & PF

Cristalhyal MW+1.4 - 2 MDa

Cristalhyal 2.21.8 - 2.2 MDa

NATIVE HYALURONIC ACID

> CRISTALHYAL range

INCI: Sodium Hyaluronate

HYDROLYZED HYALURONIC ACID

> CRISTALHYAL range INCI: Sodium Hyaluronate

> BASHYAL Powder, RENOVHYAL INCI: Sodium Hyaluronate

HYALURONIC ACID

11




HYDRINTENSE

Maris Aqua (and) Propa-nediol (and) Porphyridium Cruentum Extract

Moisture power and improvement of skin microrelief

Increase of skin's water content (ex-vivo) Increase of skin's water content upto 24hrs (5 %, 24h), Improvement of skin microrelief (5 %, D7)

None 3 - 5 %

Hydrosoluble

PORPHYRALI-NE SP

Porphyridium Cruentum Extract

Reinforcement of skin's self-defense, Film forming effect

Increase of epidermal lipid, Improve-ment of the anchoring capacity of basal membrane, Increase of beta-1-integrin and alpha-6-integrin

None 3 - 5 %

Hydrosoluble



AXOLIGHT

Water (and) Hydrolyzed Wheat Flour

Whitening, Lighte-ning

Inhibition of melanogenesis, Inhibition of melanogenesis via TRP-1 (ex-vivo)

Lightening efficacy on Asian volunteers (3 %, D56)

None 2 - 3 %

AXOLIGHT PLUS

Water (and) Hydrolyzed Wheat Flour (and) Pheno-xyethanol


Inhibition of melanogenesis, Inhibition of melanogenesis via TRP-1 (ex-vivo)

Lightening efficacy on Asian volunteers (3 %, D56)

Pheno-xyethanol

2 - 3 %

SOPHOLI-ANCE S

Candida Bombicola / Glu-cose / Methyl Rapeseedate Ferment (and) Aqua (and) Potassium Sorbate

Anti-acne, Anti-lipase, Protection of skin's self-defense, Anti-bacterial

Anti-bactericidal activity Regulation of sebum produc-tion (2 %), Acne prevention (2 %)

Potas-sium sorbate

1 - 2 %

VEGETAN

Dihydroxyacetone DHA for a natural self-tan

Self tanning (5 %) None 1 - 5 %

VEGETAN EVOLVE

Erythrulose (and) Water Long-lasting tan enhancer

More intense and more natural skin tan colour

Long-lasting and more natural skin tan colour (2%, 3h, 6h, D1, D2, D3)

None 1 - 5 %

Hydrosoluble

VEGETAN FL

Dihydroxyacetone (and) Aqua

DHA for a natural self-tan

Self tanning (5 %) None 1 - 8 %

VEGETAN FL CREATION

Dihydroxyacetone (and) Aqua (and) Parfum (and) Polysorabate 20 (and) Caprylyl/Capryl Wheat Bran/Straw Glycosides

Creative solution of DHA with a specific perfume to soften the odour during self tanning

Self tanning (5 %), Minimiza-tion of odour caused by DHA's reaction with skin (11 %)

None 2 - 15 %

VEGETAN GOLD

PEG-8 caprylic/capric glycerides (and) Water (and) Dihydroxyacetone (and) Octyldodeceth 25

The first oil compati-ble DHA

Brings a natural and very uniform tan (30%, 3h, 6h, D1, D2, D3, D4).

None 30 - 60 %

Hydrosoluble

MOISTURIZING

SKIN COMPLEXION

12

Cosmos approved CHINA approved Halal



VEGETAN PREMIUM PLUS

Dihydroxyacetone (and) Melanin

Self-tanning, Combination of DHA/Allomelanin like polymer (from caffeic acid polymerisation) for a natural tan, Quick and intense coloration and anti-oxidant activity

Antioxidant activity Kinetics of skin coloration (5 %, 3h, 6h, 8h)

None 3 - 5 % (Self-tanning products)

1 - 2 % (Glowing products)

WAKAMINE XP

Aqua (and) Undaria Pinnatifida Extract (and) Benzyl Alcohol (and) Potassium Sorbate


Reduction of skin color, Inhibition of melanin production (ex-vivo)

Comparable lightening effect as 2 % Arbutin (1 % Wakamin XP + 1 % Arbutin)


1 - 3 %

WHITESPHERE PREMIUM *Spherulite ®

Sucrose Palmitate (and) Butylene Glycol (and) Glyceryl Linoleate (and) Prunus Amygdalus Dulcis Oil (and) Aqua (and) Glycyrrhiza Glabra Root Extract (and) Magnesium Ascorbyl Phosphate (and) Undaria Pinnatifida Extract (and) Phenoxyethanol

Synergistic complex of whitening actives encapsulated in Spherulites for improved penetration of the well known whitening actives, Specific treatment against age spots

Inhibition of melanin production of Galabridin (Lit.), Inhibiton of melanin production by Undaria Pinnatifida extract (ex-vivo), Anti-oxidative capacity of ascorbic acid (Lit.), Anti-inflammatory activity of Galabridin (Lit.), Reduction of melanin production (ex-vivo)

Age spot reduction (1 %; Panelist's evaluation)

Pheno-xyethanol

0.5 - 1 %

WHITESPHERE PREMIUM XP *Spherulite ®

Sucrose Palmitate (and) Butylene Glycol (and) Glyceryl Linoleate (and) Prunus Amygdalus Dulcis Oil (and) Aqua (and) Glycyrrhiza Glabra Root Extract (and) Magnesium Ascorbyl Phosphate (and) Undaria Pinnatifida Extract (and) Benzyl Alcohol (and) Potassium Sorbate

Synergistic complex of whitening actives encapsulated in Spherulites for improved penetration of the well known whitening actives, Specific treatment against age spots

Inhibition of melanin production of Galabridin (Lit.), Inhibiton of melanin production by Undaria Pinnatifida extract (ex-vivo), Anti-oxidative capacity of ascorbic acid (Lit.), Anti-inflammatory activity of Galabridin (Lit.), Reduction of melanin production (ex-vivo)

Age spot reduction (1 %; Panelist's evaluation)


0.5 - 1 %

SKIN COMPLEXION

13

Cosmos approved potentially NaTrue Vegan suitable CHINA approved Halal



BISABOLIFE

Bisabolol Soothing, Redness reduction, Irritation reduction, Anti- oxidant

Soothing capabilities and decrease the production of three inflammatory cytokines (10 ug/mL)

Skin: Reduction of skin redness, after shaving and ap-plication of BisaboLife product vs. Placebo vs. Plant bisabolol vs. Chemical bisabolol (30 women, 18 - 64 years old, 0.2 %) Hair: Soothing action for itchy scalp (80 volunteers have tested shampoo with Bisabolife vs. plant bisabolol vs. chemical bisabolol (0.5 %, D14))

None 0.1 % - 1 %

Liposoluble

DEPOLLUTINE

Aqua (and) Arginine PCA (and) Phaeodactylum Tricornutum Extract (and) Phenoxyethanol

Limitation of polluti-on induced damage on skin

Reduction of microinflammation by targeting ICAM-1 (ex-vivo), Prevention from cigarette smoke damage (reduction of leukocyte adhesion)

Pheno-xyethanol

1 - 3 %

Hydrosoluble

GREVILLINE PF

Glycerin (and) Aqua (and) Skeletonema Costatum Extract (and) Phenoxye-thanol

Peptidic fraction of a phytoplankton, Anti-inflammatory, Anti-redness

Inhibition of IL-8 release and PLA2 activity

Reduction of UV-induced erythema (3 %, D3)

Pheno-xyethanol

1 - 3 %

Hydrosoluble

KENDI OIL

Aleurites Moluccanus Seed Oil

Natural oil rich in omega-3 fatty acids, Rich in natural tocopherol and less sensitive to oxidati-on, Dry oil with good sensoric properties

Subjective sensory assessment in comparison with Argan oil (panelist's evaluation)

None up to 100 %

Liposoluble

MARILIANCE

Aqua (and) Propanediol (and) Rhodosorus Marinus Extract

Marine neuro-soother

Reduction of TRPV1 expression, Inhibition of the expression of IL-1α, NRG, NGF R, Reduction of NGF production, Reduction of IL1α synthesis, Penetration of Mariliance in emulsion and validation of the results observed on IL-1α production (ex-vivo)

Reduction of skin sensitivity (3 %, D14, D28)

None 1 - 3 %

Hydrosoluble

MUCILIANCE FRUIT

Galactaric Acid A powerful chelating agent at a wide range of pH, can replace a number of chelating agents as EDTA or citric acid, Strong anti-oxidant and boosts preservatives

Chelating effect at wide pH-range None 0.1 - 0.2 %

Hydrosoluble

NEUROPHRO-LINE

Aqua (and) Propanediol (and) Tephrosia Purpurea Seed Extract

Overall skin stress control

Inhibition of stress hormone cortisol release, Stimulation of β-endorphin pro-duction, Global activation of anti-stress genes (transcriptomic on keratonocytes and fibroblasts), Activation of anti-stress proteins HMOX1 and NQO1 (proteomic on keratonocytes and fibroblasts), Increase of HMOX1 and NQO1 expression in epidermis (ex-vivo)

Efficacy on stressed (polluted air) skin: Improvement of skin luminocity, Reduction of skin redness, Improvement of glo-bal skin color (2 %, D14, D28), Eye dark circle reduction

None 0.1 - 2 %

Hydrosoluble

SKIN PROTEC TION

14




NYAMPLUNG OIL

Calophyllum Inophyllum Seed Oil

Dry emollient with high content at unsaponifiables and tocotrienol, Produc-tion fully ecological

SPF boosting, DNA protection from UVA and -B, Anti-oxidation, Cell repair activity after wound

None 1 - 10 %

Liposoluble

OCALINE PF

Maris Aqua (and) Aqua (and) Cucurbita Pepo Seed Extract (and) Potassium Sorbate (and) Phenoxye-thanol (and) Citric Acid

Prevention of sensitive skin by a neurocosmetic approach

Inhibition of the mast cells degranulation (ex-vivo)

Preventive effect on sensitive skin (stinging test) (5 %, D14), Soothing of irritated skin (10 %, 60 min, 180 min, 24h)

Potas-sium sorbate, Pheno-xyethanol

3 - 10 %

Hydrosoluble

OCALINE XP

Maris Aqua (and) Aqua (and) Cucurbita Pepo Seed Extract (and) Citric Acid (and) Benzyl Alcohol (and) Potassium Sorbate

Prevention of sensitive skin by a neurocosmetic approach

Inhibition of the mast cells degranulation (ex-vivo)

Preventive effect on sensitive skin (stinging test) (5 %, D14), Soothing of irritated skin (10 %, 60 min, 180 min, 24h)

Benzyl alcohol, Potas-sium sobrate

3 - 10 %

Hydrosoluble

SENSITYL

COSMOS certifica-tion pending

Water (and) Phaeodacty-lum Tricornutum Extract (and) Pentylene Glycol

The sensitive skin good mood influencer / soothing, calming, neuro-soothing, skin micro-flora rebalancing

Epigenetic control of inflammation through exosomal communication, Gene-tic control of skin soothing and calming (downregulation of a complete set of genes involved in anti-inflammatory & soothing activities), Control of the acute phase of inflammation (reduction of immune cells recruitment), Inhibition of immune cells recruitment (significant re-duction of dendritic cells) (ex-vivo 3 %), Reduction of pro-inflammatory signal through IL-8 inhibition (ex-vivo 3 %), Reduction of pain sensation through TRPV1 expression reduction (ex-vivo 3 %), Control of microbiol proliferation (ex-vivo 3 %)

Protection of skin microbiota against sensitive skin condi-tions (3 % vs placebo, D28), Restoration and protection of sensitive skin (3 %, D7), Improvement of cutaneous reactivity (3 %, D28), Soothed skin for a better mood : mood portraits (a non verbal method) Emotion decoding system (3 %, D28)

Sodium Bezoate (and) Bezoic Acid

1-3 %

Hydrosoluble

SOOTHEX CQ U/A

Dipropylene Glycol (and) Boswellia Serrata Gum

Soothing, Reduction of skin irritation, Suitable for sensitive skin formulations

Inhibition of 5-Lipoxygenase Reduction of skin reddening induced by a depilatory cream (2.5 %, from 10 min to 1 h), Reduction of AHA induced irri-tation (2 %, 5 min), Reduction of SLS induced skin irritation (2.5 %, D3, D5, D8) Itchy scalp soothing (2.5%, D28, panelist's evaluation)

None 0.5 - 2.5 %

Liposoluble, Hydroso-luble with surfactant

SOOTHEX ISA CQ U/A

Isostearyl Alcohol (and) Boswellia Serrata Gum

Soothing, Reduction of skin irritation, Suitable for sensitive skin formulations

Inhibition of 5-Lipoxygenase Reduction of skin reddening induced by a depilatory cream (2.5 %, from 10 min to 1 h), Reduction of AHA induced irri-tation (2 %, 5 min), Reduction of SLS induced skin irritation (2.5 %, D3, D5, D8) Itchy scalp soothing (2.5%, D28, panelist's evaluation)

None 0.5 - 2.5 %

Liposoluble, Hydroso-luble with surfactant

SKIN PROTEC TION

15

Distributed byIMPAG AGRäffelstrasse 128045 ZurichSwitzerland

Phone: +41 43 499 25 00 Fax: +41 43 499 25 01E-Mail: [email protected]: www.impag.ch

IMPAG Group Country OfficesSwitzerland / Zurich – www.impag.chGermany / Offenbach – www.impag.deFrance / Nancy – www.impag.frPoland / Warsaw – www.impag.plAustria / Vienna – www.impag.at

IMPAG Group Head OfficeSwitzerland / Zurich

2019 | 05

Our partner Givaudan has developed a patented micro-encapsulation system called Spherulites® which, alongside a fascinating success story, impres-ses above all for its unique technology.

Spherulites® are multi-layered microspheres of surf-actants that can encapsulate both water-soluble and oil-soluble actives, and can therefore serve as trans-porting agents in cosmetic products. This "encapsu-lation" technology has interesting auxiliary propeties:

For thousands of years, Traditional Chinese Medicine has been helping millions of people to maintain a good state of health. The aim of TCM is to achieve balance in the body’s natural equilibrium using plant extracts, which have been used in TCM throughout the millennia. These extracts are used either alone or in synergy with other natural materials to treat specific health issues.

The Ritual Essenz™ TCM collection of Givaudan Active Beauty leverages the know-ledge of modern, qualified TCM doctors who have developed exclusive extracts for skin care applications. These extracts have been crafted following the fundamental Five Elements rule of TCM (Wuxing) to fulfil the specific needs of hair and skin.

Discover the inspiring RitualEssenz™ TCM collection, consisting of 5 pure extracts and 2 blends.

Spherulite® microencapsulation technology

Non-ionic and anionic Spherulites®, for instance, improve penetration into the skin layers, while the cationic varieties improve adhesion on the skin surface. The multi-layered encapsulation can also be exploited to achieve a long-lasting action. Fur-thermore, Spherulites® allow sensitive actives to be stabilized.

Alongside a standard range, custom solutions can be developed in which several active ingredients are packed together into Spherulites®.

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For more information visit our focus topic: www.impag.ch

SPHERULITES®

RITUAL ESSENZ™ TCM

Unique encapsulation technology

Botanical extracts rooted in traditional chinese medicine

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