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INTESTINE

Duodenum

Jejunum

Ileum

Appendix

Large intrestine

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DUODENUM

MUCOSA- villi,intervillus space, epithelium,

basement membrane

lamina propria

muscularis mucosa

Submucosa

Muscularis externaSerosa

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Villi

(longitudinal section)

Fold

Apex-- narrow

Basebroad

Intervillus space which continue as intestinal gland

Lining epithelium with brush border

Lie on basement membrane

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Villi

(longitudinal section) contents

lamina propriaIntestinal glands

Fine connective tissueReticular cells

Diffuse lymphatic tissue

Lymphatic nodule in deep part(may be seen)

Muscle fibers

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Villi

(longitudinal section) contents

lamina propriaCentral lacteal- a small dialated

lymphatic vesselline with endothelium

Blood vessel- arteriole

One or more venulesNumerous Capillaries

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Villi

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Expansion of the absorptive mucosal surface

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Schematic-Villi & crypts of small intestine

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Intestinal mucosa

Note prominent villi & short intestinal glands

opening between the bases of villi

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Duodenum

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Duodenum - LS

Note submucosal Brunners glands

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L.S. Duodenum

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Duodenum

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Duodenum PAS/haematoxylin

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Duodenum

-Alcian blue

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Intestinal villi & crypts

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Paneth cell in base of

crypt of Lieberkuhn

Phloxine-tartrazine stain

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Intestinal villi

Ly = lymphocytesP = plasma cell

M = Smooth muscle fibres

C = capillaries

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Intestinal villi

PAS/Iron haematoxylin/Orange G

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Intestinal villi -TS

L = lacteal

Ly = lymphocytes

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Intestinal villi & crypts

Enzyme histochemical method for Alkaline phosphatase

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Carmine perfusion method to demonstrate the blood supply

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Microcirculation of intestinal villus

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LS of a Jejunal villus

Lacteal

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Intestinal villi to demonstrate chylomicrons

Sudan black stain

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Intestinal villi - tip

Toluidine blue

SB=Surface brush border

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EM - Jejunal villi

Foliate & finger- like

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EM-Duodenal Villi &underlying crypts

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Intestinal villi & crypts

Scanning EM of intestinal mucosa viewed from the lumen

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Scanning EM of intestinal mucosa viewed from the lumen

after removal of the epithelium

Foliate villi Openings of recesses occupied by the glands

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Intestinal microvilli & glycocalyx coat

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Oligosaccharide chains emerging from the

outer leaflet of plasma membrane

EM T S f i illi

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EM T.S. of microvilli

Note actin filaments in the core

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Bundles of actin filaments extending from microvilli

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Goblet cell & surrounding enterocytes

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Enterocytes of small intestine - EM

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Enterocytes of small intestine - EM

f

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Enterocytes of small intestine - EM

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Base of crypt of Lieberkuhn

P ti f P th ll

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Portion of Paneth cell

S ll i t ti

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Lymphoid follicle

Small intestine

S i EM E ith li l h id f lli l

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Scanning EM Epithelium over lymphoid follicle

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M cells

S h ti t ti f I A ti

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Schematic representation of IgA secretion

S b ith li l fib bl t f t t d

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Subepithelial fibroblasts fenestrated

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Schematic representation of Ileum

Ileum

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Ileum

Note Peyers patches

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Ileum

Lipid droplets in intestinal lining cell

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Lipid droplets in intestinal lining cell

Schematic ultrastructure of intestinal absorptive cell

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Schematic ultrastructure of intestinal absorptive cell

Fasting state Lipid rich meal

Schematic representation of chylomicron formation

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Schematic representation of chylomicron formation

Chylomicrons in intercellular space

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Chylomicrons in intercellular space

Ileocaecal junction

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Ileocaecal junction

T S of Appendix

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T.S. of Appendix

Appendix -T.S.

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Appendix T.S.

Appendix -T.S.

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Appendix T.S.

Appendix

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Appendix

Note lymphoid follicle & lamina propria

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Large intestine

L S of Large intestine

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L.S. of Large intestine

Scanning EM of descending colon

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Scanning EM of descending colon

Large intestine note crypts & goblet cells

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Large intestine note crypts & goblet cells

L.S. T.S.

Crypt from rectal mucosa

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Crypt from rectal mucosa

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Large intestine

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TS Alcian blue/Van Gieson H/E

Scanning EM of submucous nerve plexus

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Scanning EM of submucous nerve plexus

Intestinal myenteric plexus

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Intestinal myenteric plexus

Multipolar neuron in myenteric plexus

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Multipolar neuron in myenteric plexus

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Recto-anal junction