GFS Chemicals, Inc.Innovation and Commercialization through Chemistry ISO 9001:2008 Certified

• Batch Manufacturing for R&D through Commercialization• Flexible Production Capabilities for over 80 years• Inorganic and Organic Manufacturing Expertise• Extensive Expertise in Manufacturing Technologies and Chemistries • Exceedingly Responsive to Customer Inquiries – Confidential• Achieving Accurate and Reliable Production Deadlines

• Semi-Custom Chemistry to Meet Tight Customer Specifications• Problem Solving Chemists Complement Your Project Team• Supporting Major Industry Around the Globe• Manufacturing High Quality Chemicals up to metric tons• Custom Packaging, Drying and Production Competence• Your Global Sourcing Partner

Steel HutchinsonPresident, GFS Chemicals

Industries Served

• Environmental• Semiconductor• Pharmaceutical• Flavor & Fragrance• Superconductivity• Petrochemical• Agricultural• Automotive• Defense • Biotechnology• Power and Energy (Fuel

Cells, Batteries, etc)

Industries Served

• Environmental• Semiconductor• Pharmaceutical• Flavor & Fragrance• Superconductivity• Petrochemical• Agricultural• Automotive• Defense • Biotechnology• Power and Energy (Fuel

Cells, Batteries, etc)

Industries Served

• Electronics• Chemicals• Aerospace• Polymers• Coatings• Catalysts• Optics• Contract Manufacturing• Water treatment and

Analysis• Beverage/Dairy• Quality Control Laboratories

Industries Served

• Electronics• Chemicals• Aerospace• Polymers• Coatings• Catalysts• Optics• Contract Manufacturing• Water treatment and

Analysis• Beverage/Dairy• Quality Control Laboratories

Innovation and Growth1928 1940’s 1960’s 1970’s 1980’s

Founded, Columbus Ohio. Perchlorate salts defined early business

Development of trace metal acids (ppt grade acid)

Rare Earth products introduced (CAN) Development of heteroaromatic ligands

Acquisition of Karl Fischer product line

Collaboration on first chrome etchants

Innovation and Growth

Heavy acquisition period includes quaternary salts, sodium biphenyl & Farchan acetylenics

Perchloric acid plant built($2.5M US)

ISO 9000 certification

Aquisition of APS Analytical Standards for turbidimeters, colorimeters and spectrophotomers

New organic production facility built ($3.5M US)

1990’s 1997 1997 2001 2003

Innovation and Growth

Perchloric Acid expansionInorganic and Organic research labs built

UDRI Chrome IV Replacement Project

Beta Phase Tri-Calcium Phosphate - Artificial Bone Scaffold

Purchase of Catalog Distribution Center, Private Labelling Operation and Laboratory Reagents Manufacturing

SOCMA Chem Steward Tier II Certification Ammonia Borane Manufacturing Partnership

2004 2007 2008 2009 2010

Safety and Environment

• GFS is a Tier II Chem Stewards organization focused on safety improvement practices and waste minimization, recovery policies and controls

• Selected Employees are DOT, IATA and IMO certified to support all modes of material logistics to ensure safe and legal shipments world wide.

Safety and Environment

• GFS is a Tier II Chem Stewards organization focused on safety improvement practices and waste minimization, recovery policies and controls

• Selected Employees are DOT, IATA and IMO certified to support all modes of material logistics to ensure safe and legal shipments world wide.

Compliance and Quality

• GFS organic production operations are a zero discharge facility compliant with all local and federal EPA regulations

• We adhere to ISO 9001:2008 standards for quality practices and have been ISO certified since 1997

Organic Manufacturing

Leaders in the development and commercialization of specialty alkynes and derivatives

Product Offering

• GFS Chemicals remains focused on a core set of synthetic methodologies

• In support of alkyne production, we offer down

stream intermediates such as olefins, heteroaromatics and heterocycles

• We offer over 2000 organic chemicals in our product base

Core Synthetic Chemistry

Na & Li/Liquid Ammonia Chemistry– Alkylations– Aminations– Reductions (Birch, trans)– Ethynylations

Halogenations– Brominations– Chlorinations– Iodinations

Core Synthetic Chemistry

Alkyne Chemistry– Eliminations– Ethynylations– Sonogashira– Glaser Coupling– Cadiot-Chodkiewicz– Click Chemistry

Core Synthetic Chemistry

• Organometallic Chemistry– Grignard– Alkyl lithium– Coupling (Suzuki, Stille,

Negishi, Kumada)– Heck Reaction– LI/NA Amide– Cis-reductions

Core Synthetic Structures

• Alkynes– Aromatic– Terminal– Internal– Alcohols– Ketones– Acids– Conjugated

• Olefins– Cis/trans– En-yne– Cyclic– Grignards– Vinyl– Aryl– Alkyl

Core Synthetic Structures

• Halogenated Organics– Aklynes (Spelling??)– Olefins– Alkyl– Aromatic

•Heteroaromatic– Quinolines – Indoles– Pyrimidines– Bipyridines– Phenanthrolines– Terpyridines

Inorganic Bulk Manufacturing

U.S. Based Inorganic Product Development and Manufacturing

Inorganic Specialties

• Perchloric acid & Salts• Ceric Ammonium Nitrate (Etchants & Catalysis)• Purified compounds for metal complexes• Ultra dry salts for moisture sensitive applications• Rare Earths, Lithium, Sodium and Magnesium salts

& solutions• Precious metal ion exchange resins

Bulk Inorganic Salts

• Nitrates • Sulfates• Chlorides• Perchlorates• Carbonates• Periodates

• Oxalates• Acetates• Formates• Phosphates• Citrates

Specialty Inorganics

• Rubrene (OLED & Dye) • Anhydrous Cerous Chloride (Fuel Cell & Grignard

Initiator)• Hydroxyquinoline, Aluminum Salt (OLED)• Polyoxometalate complexes

Bulk Inorganics

• Lithium Perchlorate (Battery Electrolyte & Organic Catalyst)

• Lithium Carbonate, 99.998% (Lithium Crystals & Organic Catalyst)

• Lithium Iodide (Battery Electrolyte & Organic Catalyst• Precious Metal Salts (Silver Nitrate)• Ammonium Borane (OSU & EBA &D)

In-House Quality Control Support

• Full wet chemisty lab• Karl Fischer• Florescence

spectrophotometer• Ion Chromatograph• pH & Conductivity• Six New Lab Suites, dedicated

to new product and process development

• XP environment in two suites• PhD and Masters level chemists

supporting operations

• Gas Chromatography• Coulometric and Volumetric

Karl Fischer Systems• HPLC• GC/MS• UV VIS• FT IR • Wet Chemistry lab• IC• Melting Point• ICP• AA

What’s New

• Expanded Inorganic drying capacity/capability• Expanded Organic and Inorganic distillation capacity• Development of Organic Iodides/Iodoalkanes• High purity organic acids for etchants• Acquisition of novel nanosphere polymer technology• New Product Development Labs for Inorganic and

Organic Compounds • FDA inspected production suite• R&D Lab expansion• Dry Room for ultra low moisture product

handling/packaging• Specialty Grignard reagents

Dry Room Capabilities

• < 1% Relative Humidity• - 45° C Dew Point• Customized anhydrous material

handling• Custom packaging capabilities• Supporting materials < 100 ppm

H2O• Designed for Battery Grade and

Fuel Cell Grade materials

Robust Distillation Capabilities

• Increased capacity:– Single pass distillation– Fractional distillation

• High vacuum capability• Wiped film distillation for heat-

sensitive compounds• Extensive glass equipment for

handling corrosives• Low trace metal impurities

Customer Metrics

On time delivery (NEED TO SAY SOMETHING HERE)

Inventory Availability Lead Time Accuracy Product QualityTimely DeliveryProduct Information/KnowledgeCustomer Satisfaction

International Operations

• Sourcing Operations in Shanghai China• Serving over 80 countries

worldwide• www.GFSInternational.com– Japanese– German– French– Spanish

GFS Catalog Operations

• 70,000 Sq Ft. Operation, Manufacturing and Distribution Center

• Repack and Fulfillment Center• Private Label Operation• Amco Clear Water Analysis Division• Bottling Operations• Quality Control Labs• Manufacturing and Sourcing over 4000

Analytical Reagents