Georgina Grant - ActiFormCool
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Transcript of Georgina Grant - ActiFormCool
A proposed trial using ActiFormCool® as a prophylaxis to minimise radiation skin reaction for breast patients requiring full bolus.
Author: Georgina Grant. Lead Radiographer, GenesisCare, Elstree.
Breast/Chestwall skin reactions.For all breast patients:
• Radiographers assess skin reactions using the Radiation Therapy Oncology Group (RTOG) scoring matrix.
• The RTOG scores recorded are: - Baseline- Weekly- Final fraction- Follow-up
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RTOG Scoring Matrix
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RTOG Score Description
RTOG 0 No visible change to skin.
RTOG 1 Faint or dull erythema. Mild tightness of skin and itching may occur.
RTOG 2 Bright erythema/dry desquamation. Sore, itchy and tight skin.
RTOG 2.5 Patchy moist desquamation, Yellow/pale green exudate. Soreness with oedema.
RTOG 3 Confluent moist desquamation. Yellow/pale green exudate. Soreness with oedema.
RTOG 4 Ulceration, bleeding, necrosis (rarely seen)
Skin AdviceAll patients are given to appropriate skin care advice before, during and after their radiotherapy. However, the loss of skin sparing effect when using full bolus often leads to:
• Earlier onset and increased skin reaction.• More pain and discomfort.• Need for nursing intervention.• Longer recovery period.• Psychological issues.
Small centre-based audit completed comparing patients with no bolus to those with full chestwall bolus.
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Eight randomly selected No Bolus patients Bolus Dose RTOG
BaselineRTOG
Week 1RTOG
Week 2RTOG
Week 3RTOG
Week 4RTOG
Week 5 Final RTOG Follow up RTOG
No Bolus
40Gy/15# + 10Gy/5# IMRT boost 0 0 1 1 2 2
40Gy/15# + 10Gy/5# IMRT boost 0 0 0 1 1 1 1
40Gy/15# + 10Gy/5# IMRT boost 0 0 1 1 1 1
40Gy/15# + 10Gy/5# IMRT boost 0 0 1 2 2
40Gy/15# + 10Gy/5# IMRT boost 0 0 1 1 2 1
40Gy/15# + 10Gy/5# IMRT boost 0 0 1 1 1
50Gy/25# 0 0 1 1 1 2 2 2
50Gy/25# 0 0 1 2 2 2 2
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Eight Full Bolus patientsBolus Dose RTOG
BaselineRTOG
Week 1RTOG
Week 2RTOG
Week 3RTOG
Week 4RTOG
Week 5 Final RTOG Follow up RTOG
Full Bolus
40Gy/15# 0 0 1 2 2 2.5
40Gy/15# 0 0 2 2 2 2
40Gy/15# 0 0 2 2 2 2.5
40Gy/15# + 10Gy/5# IMRT boost 0 0 1 1 2 2 2
50Gy/25# 0 1 2 2 2 2.5 2.5
50Gy/25# 0 0 1 2 2 2.5 2.5
50Gy/25# 0 2 1 1 2.5 2.5
50Gy/25# Rt and Lt Chestwall 0 0 1 1 2 2.5 2.5 2.5
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ActiFormCool®.
• Decided that intervention needed to try and reduce the number of patients developing RTOG skin toxicity score 2.5.
• BCN informed us of the product ActiFormCool®.
• Representative from the manufacturers (ActivaHealthcare) attended to give a demonstration.
• All clinical staff impressed by the cooling effect of the product.
• Audits undertaken by radiotherapy nursing staff in a number of NHS hospitals with good results on radiotherapy skin reactions.
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Ionic Sheet Hydrogel Dressing
• 70% Water
• 30% Acrylic Polymer
• Preservative - phenoxyethylene
An Ionic hydrogel responds dynamically to the condition of the wound
It can either donate or absorb fluid to maintain optimal moisture levels
Permeable to water vapour, gases and small protein molecules
Impermeable to bacteria
Slide courtesy of ActivaHealthcare
• Reduces wound pain and improves patient comfort. Pain Management in Leg Ulcers using ActiFormCool, Stephen Young, Sylvia Hampton. Wounds UK Journal, November 2005.
• Dynamically responds to wound changes by donating or absorbing moisture
• For use on dry to highly exuding wounds• For all stages of the wound healing • Easy to use
Slide courtesy of ActivaHealthcare
Service DevelopmentStarted a thought process at Elstree….
• Could this product be used to help reduce skin reaction?• At what stage of radiotherapy should it be used?• How would it be held in position?• How often should it be applied?• Could it be used as a prophylaxis?
Discussions started between GenesisCare Elstree and ActivaHealthcare regarding a possible trial of the product.
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Alignment with our Visions and Values
The use of ActiFormCool® in this trial would meet all of the Genesiscare Visions and Values, particularly:
Quality: Providing the best quality available to our patients
Collaboration: ActivaHealthcare and GenesisCare working together. Easier access to new, innovative products.
Compassion: To improve the patient journey by reducing pain and discomfort during and after radiotherapy.
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Alignment with our Visions and Values
Innovation: GenesisCare to be the first healthcare provider to use ActiFormCool® prophylactically. ActivaHealthcare are excited to be part of the trial as it will be the first of its kind.
Outcomes: The patient will benefit from less nursing intervention following the completion of radiotherapy. This could then be implemented as best practice throughout all GC Centres. • Could lead to Medical Journal publications.• Good for increasing patient referrals.
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Alignment with our Visions and Values
Proposed Methodology• Oncologists informed if their patient is involved.
• Patient consent required for the trial.
• The ActiFormCool® pad would need to be kept in position from fraction 1 until the completion of radiotherapy for 24 hours/day. Removal for treatment and washing only.
• Patient still to apply E45 to intact skin.
Actifast® tubular retention bandages to be used to maintain cool pad position.
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Proposed Methodology• Radiotherapy Skin Reaction Evaluation form will be
completed for each patient from Baseline RTOG score to FU RTOG score.
• Daily Navigator notes and weekly RTOG scores recorded in Mosaiq.
• RTOG scores will be retrospectively compared to patients who received full bolus without the intervention of ActiFormCool®.
ActivaHealthcare to provide all resources.Page 15
Next Steps…..• New Research Initiative Evaluation form has been
completed.• Needs to be passed by members of SMT.• Needs to be passed by an Ethics committee.• Hopefully start the trial in Early 2017.
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Thank-you