George Ntaios MD, MSc (ESO Stroke Medicine), PhD, FESO University of Thessaly, Larissa, Greece Nice...

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George Ntaios MD, MSc (ESO Stroke Medicine), PhD, FESO University of Thessaly, Larissa, Greece Nice 08/05/2014 A short introduction on European Stroke Conference / Stroke Guidelines

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Transcript of George Ntaios MD, MSc (ESO Stroke Medicine), PhD, FESO University of Thessaly, Larissa, Greece Nice...

Page 1: George Ntaios MD, MSc (ESO Stroke Medicine), PhD, FESO University of Thessaly, Larissa, Greece Nice 08/05/2014 A short introduction on European Stroke.

George Ntaios MD, MSc (ESO Stroke Medicine), PhD, FESO

University of Thessaly, Larissa, Greece

Nice 08/05/2014

A short introduction on

European Stroke Conference / Stroke Guidelines

Page 2: George Ntaios MD, MSc (ESO Stroke Medicine), PhD, FESO University of Thessaly, Larissa, Greece Nice 08/05/2014 A short introduction on European Stroke.

Disclosures

Scholarships: European Stroke Organization; Hellenic Society of Atherosclerosis.Honoraria: Medtronic; Quintiles.Speaker fees: Sanofi; Boehringer-Ingelheim.Consultant fees: Boehringer-Ingelheim.Support to attend conferences: Bayer; Sanofi-Aventis; Pfizer; Lundbeck; Boehringer-Ingelheim; Galenica; Elpen; Bristol Myers Squibb. Participation in trials:

ENOS / National co-ordinator (Greece). BPREVISE / Principal investigator. FOURIER / Sub-investigator. GLORIA / Sub-investigator.

Page 3: George Ntaios MD, MSc (ESO Stroke Medicine), PhD, FESO University of Thessaly, Larissa, Greece Nice 08/05/2014 A short introduction on European Stroke.

Grading of

Recommendations,

Assessment,

Development and

Evaluation

GRADE

Page 4: George Ntaios MD, MSc (ESO Stroke Medicine), PhD, FESO University of Thessaly, Larissa, Greece Nice 08/05/2014 A short introduction on European Stroke.
Page 5: George Ntaios MD, MSc (ESO Stroke Medicine), PhD, FESO University of Thessaly, Larissa, Greece Nice 08/05/2014 A short introduction on European Stroke.

Population In children during summertime

Intervention chocolate ice-cream

Comparator studying mathematics

Outcome* happiness

Specify the PICO question(s)

Page 6: George Ntaios MD, MSc (ESO Stroke Medicine), PhD, FESO University of Thessaly, Larissa, Greece Nice 08/05/2014 A short introduction on European Stroke.

Assessment of quality of studies

RCTs start high

Observational studies start low

Page 7: George Ntaios MD, MSc (ESO Stroke Medicine), PhD, FESO University of Thessaly, Larissa, Greece Nice 08/05/2014 A short introduction on European Stroke.

Assessment of quality of studies (downgrade)

Study design and execution (bias)

Inconsistency (heterogeneity, I2)

Indirectness

Imprecision (number of events, confidence intervals)

Publication bias (funnel plot)

Page 8: George Ntaios MD, MSc (ESO Stroke Medicine), PhD, FESO University of Thessaly, Larissa, Greece Nice 08/05/2014 A short introduction on European Stroke.

Assessment of quality of studies (upgrade)

Large magnitude of the effect

Dose – response relation

Page 9: George Ntaios MD, MSc (ESO Stroke Medicine), PhD, FESO University of Thessaly, Larissa, Greece Nice 08/05/2014 A short introduction on European Stroke.

Grade of evidence

Page 10: George Ntaios MD, MSc (ESO Stroke Medicine), PhD, FESO University of Thessaly, Larissa, Greece Nice 08/05/2014 A short introduction on European Stroke.

Summary of Findings (SoF) tables

Page 11: George Ntaios MD, MSc (ESO Stroke Medicine), PhD, FESO University of Thessaly, Larissa, Greece Nice 08/05/2014 A short introduction on European Stroke.

Panel discussionOverview


Explaining Stroke __________________ © 2010 National Stroke Association. National Stroke Association is collaborating with American Stroke Association.

Explaining Stroke __________________ © 2010 National Stroke Association. National Stroke Association is collaborating with American Stroke Association.

2 Stroke and 4 Stroke Engine

2 Stroke and 4 Stroke Engine

Toronto Stroke Rehab Referral System...Type of Stroke: (tick one) Stroke R body Stroke L body Stroke no paresis Stroke bilateral Other stroke Complete the AlphaFIM® Instrument items

Toronto Stroke Rehab Referral System...Type of Stroke: (tick one) Stroke R body Stroke L body Stroke no paresis Stroke bilateral Other stroke Complete the AlphaFIM® Instrument items

Coagulants Aluminium sulphate - Al 2 (SO 4 ) 3 .18H 2 O Iron sulphate - FeSO 4 . 7H 2 O

Coagulants Aluminium sulphate - Al 2 (SO 4 ) 3 .18H 2 O Iron sulphate - FeSO 4 . 7H 2 O

Stroke Emergency! Don't Have a Stroke ....

Stroke Emergency! Don't Have a Stroke ....

Aanpak van CVA - forumig.be · Major bleeding. Effects of NOACs vs warfarin on stroke or systemic embolism in patients with AF and previous stroke or TIA Ntaios G et al. Stroke 2012;42:3298–304

Aanpak van CVA - forumig.be · Major bleeding. Effects of NOACs vs warfarin on stroke or systemic embolism in patients with AF and previous stroke or TIA Ntaios G et al. Stroke 2012;42:3298–304

SAM Stroke Community Presentation GuideSAM Stroke Community Presentation GuideSAM Stroke Community Presentation GuideSAM Stroke Community Presentation GuideSAM Stroke Community Presentation

SAM Stroke Community Presentation GuideSAM Stroke Community Presentation GuideSAM Stroke Community Presentation GuideSAM Stroke Community Presentation GuideSAM Stroke Community Presentation

The World Stroke Organisation STROKE SUPPORT ... STROKE SUPPORT ORGANISATION TOOLKIT 1.1 Introduction Stroke Support Organisations (SSOs) have a key role in supporting stroke survivors

The World Stroke Organisation STROKE SUPPORT ... STROKE SUPPORT ORGANISATION TOOLKIT 1.1 Introduction Stroke Support Organisations (SSOs) have a key role in supporting stroke survivors

NIH Stroke Scale - Internet Stroke Center

NIH Stroke Scale - Internet Stroke Center

4-Stroke and 2-Stroke Cycles

4-Stroke and 2-Stroke Cycles

Stroke Rehabilitation Screening and Assessment Tools · Heart and Stroke Foundation Stroke Rehabilitation Canadian Stroke Best Practice Recommendations Stroke Rehabilitation Screening

Stroke Rehabilitation Screening and Assessment Tools · Heart and Stroke Foundation Stroke Rehabilitation Canadian Stroke Best Practice Recommendations Stroke Rehabilitation Screening

Primary Stroke Center Acute Stroke Network

Primary Stroke Center Acute Stroke Network

Stroke Systems and Stroke Scales in the Management of Acute Stroke Patients

Stroke Systems and Stroke Scales in the Management of Acute Stroke Patients

Stroke: diagnosis and initial management of acute stroke ... · Diagnosis and initial management of acute stroke and ... Stroke: diagnosis and initial management of acute ... stroke

Stroke: diagnosis and initial management of acute stroke ... · Diagnosis and initial management of acute stroke and ... Stroke: diagnosis and initial management of acute ... stroke

NOACs (new oral anticoagulants): are we ready for a wide use after stroke? YES George Ntaios University of Thessaly, Larissa, Greece 2013 Joint meeting.

NOACs (new oral anticoagulants): are we ready for a wide use after stroke? YES George Ntaios University of Thessaly, Larissa, Greece 2013 Joint meeting.

Controversy 2 : “Prime time for acute prevention with double anti-aggregation” Moderator: George NTAIOS (Greece)

Controversy 2 : “Prime time for acute prevention with double anti-aggregation” Moderator: George NTAIOS (Greece)

Surviving Stroke: Post-Stroke Rehabilitation

Surviving Stroke: Post-Stroke Rehabilitation

A Stroke, is a Stroke, is a Stroke…or Is It????

A Stroke, is a Stroke, is a Stroke…or Is It????

The ASTRAL score to predict functional outcome in acute ischemic stroke University of Thessaly, Larissa, Greece George Ntaios.

The ASTRAL score to predict functional outcome in acute ischemic stroke University of Thessaly, Larissa, Greece George Ntaios.

Stroke Syndromes Dr. Meg-angela Christi Amores. Stroke Cerebrovascular disease ischemic stroke, hemorrhagic stroke, and cerebrovascular anomalies such.

Stroke Syndromes Dr. Meg-angela Christi Amores. Stroke Cerebrovascular disease ischemic stroke, hemorrhagic stroke, and cerebrovascular anomalies such.