FROM ZERO TO HERO DEVELOPING A BEST PRACTICE IN VAP … · • ETT: Covidien Taperguard EVAC •...
Transcript of FROM ZERO TO HERO DEVELOPING A BEST PRACTICE IN VAP … · • ETT: Covidien Taperguard EVAC •...
FROM ZERO TO HERODEVELOPING A BEST PRACTICE IN VAP-PREVENTION
November 2016dr. Walter Swinnen
DISCLOSURE
NONE
12
beds
1200 patients / year
Mixed medical/surgical
ICU
Closed type
6 intensivists
25 FTE nurses
0,6 FTE physio
1 FTE logistics
5,4 %
Mortality
0,36
SMR (SAPS-2)
1,4 VAP
/ 1000 VD
5 jan 2011
Last cathetersepsis
CORE DATAICU-azSB
WHAT'S SO SPECIAL ABOUT VAP?
SPECIAL CIRCUMSTANCESSpecial patients
Special environment
After a few days
of mechanical ventilation
SPECIAL CIRCUMSTANCES
SPECIAL CONSEQUENCES
SPECIAL CONSEQUENCES
Search date Nov 21th 2016
BIJZONDERE GEVOLGENSPECIAL CONSEQUENCES
21,720,7
17,9
15,614
1615,2
13
15,8
11,812,7
17,9
12,5
8,9
12,9
7,2 7,38,6
6,3
9,9
0
5
10
15
20
25
30
35
40
99 0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
Institute Public HealthNavigator
TO IMPROVE DIFFICULT IS
TO IMPROVE IS DIFFICULT
≠
TO IMPROVE IS DIFFICULT
NOTHING LASTS FOREVER…9 QUALITY INDICATORS OF ESICM 2012
• ICU OK with okay with national legislation
• Intensivist 24/24 available
• Multidisciplinary consultation
• Incident reporting
• Standardized hand over at discharge
• Standardized Mortality Ratio (SMR)
• Readmission < 48u after discharge
• Unplanned extubations
• Catheter associated blood stream infections
26,9
36,8
2,64,6
3,21,4
0
5
10
15
20
25
30
35
40
99 0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
VAP > D2 / 1000 ventilatiedagen
FROM ZERO TO HERO
FROM ZERO TO HERONOT THAT EASY !
• Exclude patients with LOS < 48h• Stop measuring 48h after extubation• Count patients with duration of MV < 48h• Measure continuously, or:
– You lose the attention of your collaborators– You lose knowledge of registration & definitions
VAP incidence = VAP (n) * 1000
ventilator days (n)
UNIFORM DEFINITIONS
Peer review of possible VAP’s:
– Promote identification
– Data manager checks definitions
– 2 peers review data
– Majority wins
USE UNIFORM DEFINITIONS
26,9
36,8
0
5
10
15
20
25
30
35
40
99 0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
EVOLUTION VAP ICU-azSB2000: FIRST FEEDBACK
• Better adherence to scoring guidelines by:– Sensitize the intensivists
– Training in correct use of definitions
Data transfer to IPH
26,9
36,8
29,3
26,7
18,2
0
5
10
15
20
25
30
35
40
99 0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
• Better adherence to scoring guidelines by:– Sensitize the intensivists
– Training in correct use of definitions
• Better results:– Hawthorne effect?
– Real improvement?
– Face lift? i.e. false negatives?
• 2004: validation study IPH Q1-2001– Sensibility: 69,1% (benchmark: 53,7%)
– Specificity: 96,1%
Data transfer to IPH
Sto
p f
eed
bac
k
EVOLUTION VAP ICU-azSB2001-2003
New
HEL
ICS-
def
inti
on
26,9
36,8
29,3
26,7
18,2
12,6
18,6
0
5
10
15
20
25
30
35
40
99 0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
Data transfer to IPH
• Dark ages:– No feedback IPH
– Calculate results with NISH-software
• 2004: aspiration technique– Training
– Standing order
• S2-2004 & S1-2005:– Test subglottic suctioning
– Result: negative
EVOLUTION VAP ICU-azSB2004-2005
26,9
36,8
29,3
26,7
18,2
12,6
18,6
10,2
0
5
10
15
20
25
30
35
40
99 0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
Data transfer to IPH
EVOLUTION VAP ICU-azSB2006
Sto
p d
atat
ran
sfer
IPH
26,9
36,8
29,3
26,7
18,2
12,6
18,6
8,2
20,5
0
5
10
15
20
25
30
35
40
99 0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
EVOLUTION VAP ICU-azSB2007
REVIEW OFEVIDENCE
TRAINING ICU-STAFFW/ NEW STUFF
DATACOLLECTIONREPORT DATA
EVERY Q TO STAFF
26,9
36,8
29,3
26,7
18,2
12,6
18,6
8,2
20,5
0
5
10
15
20
25
30
35
40
99 0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
EVOLUTION VAP ICU-azSB2008
• New new stuff:– Closed airway suctioning
– MDI-port
– ETT with PU-cuff
– Manual cuff pressure measurement
• Poster in every room
26,9
36,8
29,3
26,7
18,2
12,6
18,6
8,2
20,5
22,6
0
5
10
15
20
25
30
35
40
99 0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
EVOLUTION VAP ICU-azSB2008
• Nurses’ observations: closed suction doesn’t work
• New focus: micro-aspiration
Subglottic suctioning• Evacuation of secretions
above the cuff
• Manual vs. automatic
• Intermittent vs. continu
Cuff• Design: barrel vs. cylindric
vs. tapered
• Material: PVC vs. PU vs. silicone
Cuff pressure
• Intermittent vs. continuousmeasurement
• Automatic vs. manual correction
HOW TO TACKLE MICRO ASPIRATION ?
MICRO ASPIRATION
5 min
72 h
26,9
36,8
29,3
26,7
18,2
12,6
18,6
8,2
20,5
22,6
0
5
10
15
20
25
30
35
40
99 0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
EVOLUTION VAP ICU-azSB2009
X
26,9
36,8
29,3
26,7
18,2
12,6
18,6
8,2
20,5
22,6
10,1
7,7
0
5
10
15
20
25
30
35
40
99 0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
EVOLUTION VAP ICU-azSB2009-2010
26,9
36,8
29,3
26,7
18,2
12,6
18,6
8,2
20,5
22,6
10,1
7,7
0
5
10
15
20
25
30
35
40
99 0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
EVOLUTION VAP ICU-azSB2009-2010
• New oral care materials:– Chlorhexidine 0,2%
– Oral care system with social control
EVOLUTION VAP ICU-azSB2011
26,9
36,8
29,3
26,7
18,2
12,6
18,6
8,2
20,5
22,6
10,1
7,7
11,4
0
5
10
15
20
25
30
35
40
99 0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
• Project Fed Dpt Health, cell Quality
• Development Belgian VAP-bundle
• Synergistic combination of ‘best practices’ that improve care (1+1=3).
• Evidence based & 'standard of care’.
• Very clear, measurable elements: yes / no answers.
• All the elements in the bundle must be carried out together: non-compliance with one element =non-compliance of the complete bundle.
BUNDLE
> 30° elevation Sedation stop? Cuff pressurecontrol
Oral Care Chlorhexidine
Optional: Subglotticsuctioning
BELGIAN VAP-BUNDLE v2012
azSB VAP-BUNDLE v2012
024681012141618202224262830
0%10%20%30%40%50%60%70%80%90%
100%
Totale compliantie Gemiddelde compliantie Aantal pneumoniën /1000 dagen
COMPLIANCE azSB 2013
97,3
99,9
99,997,3
99,9
0
20
40
60
80
100Total
30° elevation
Sedation vacationOral Care
Cuff pressure control
26,9
36,8
29,3
26,7
18,2
12,6
18,6
8,2
20,5
22,6
10,1
7,7
11,4
2,64,6
0
5
10
15
20
25
30
35
40
99 0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
EVOLUTION VAP ICU-azSB2012-2013
97,3
99,9
99,997,3
99,90
20
40
60
80
100Total
30° elevation
Sedationvacation
Oral Care
Cuff pressurecontrol
26,9
36,8
29,3
26,7
18,2
12,6
18,6
8,2
20,5
22,6
10,1
7,7
11,4
2,64,6
0
5
10
15
20
25
30
35
40
99 0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
EVOLUTION VAP ICU-azSB2012-2013
• Sedation protocol with RASS
26,9
36,8
29,3
26,7
18,2
12,6
18,6
8,2
20,5
22,6
10,1
7,7
11,4
2,64,6
3,21,4
0
5
10
15
20
25
30
35
40
99 0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
EVOLUTION VAP ICU-azSB2014-2015
26,9
36,8
29,3
26,7
18,2
12,6
18,6
8,2
20,5
22,6
10,1
7,7
11,4
2,64,6
3,21,4
0
5
10
15
20
25
30
35
40
99 0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
IPHNAVIGATOR
azSB
EVOLUTION VAP IZ-azSB1999-2015
CRITICISM
COSTS OF INNOVATION
You
You’ll want to be here
COST
For the hospital• ETT: 200x
– € 20 vs. € 2
• Cuff controller: 12x– € 1.440 vs. € 141
• Suction pumps: 12x– € 650– Reservoirs 200mL: € 3– Reservoirs 1L: € 1
Total: € 28.080Additional expenses: € 21.080
BENEFIT
For society
3 VAP’s = € 30.000 benefit = cost neutral
COST-EFFECTIVE ?
22
18
7
5
8
23
21
16 16
20
18 18
23
8
6
7 8 9 10 11 12 13 14 15
n VAP obs n VAP exp IPH
COST:€ 80.000
IMPACT OP DE UITGAVEN
SAVINGS:€ 660.000
COST-EFFECTIVE ?
18
6
32
6
12
816
103635
9
346
20
45
8 10
68
45
6
12
51
2410
22 88
9
3612
6
9
128
30
6
6
199
9106
156 8
6
9
9
1011
8
12
2815
7
11
8
18
8
7
6
9
8
15
12
12
10 12
67 accredited ICU’s, 1152 beds
IMAGINE…
REPRODUCIBILITY ?
azSB
• ETT: Teleflex Isis
• Subglottic suctioning, no data about technique
• Non-continuous cuff pressure measurement
• > 30° elevation head end bed
• Oral care with chlorhexidine
• Daily reassessment of sedation goals
• ETT: Covidien Taperguard EVAC
• Intermittent subglottic suctioning pump
• Continuous cuff pressure measurement
• > 30° elevation head end bed
• Oral care with hexetidine
• No sedation goals
Crit Care Med 2015; 43(1):22-31
22,6 7,7 VAP/1000 VD
20 9,8 VAP/1000 VD
EVERY ADVANTAGE HAS ITS DISADVANTAGE
Johan Cruyff, reversed
GEMOTIVEERDE DEELNEMERS
MEAN LENGTH OF STAY
4,28
3,973,87
3,59 3,53 3,50 3,56
3,323,43
3,37
2,50
3,00
3,50
4,00
4,50
5,00
6 7 8 9 10 11 12 13 14 15
BED OCCUPANCY 2015
DISADVANTAGES
Calender day based
3961 d
90,4 %
Exact
(minute based)
2763,63 d
63,1 %
CONSEQUENCES
STAFF REDUCTION INCOME DROP
X
CONSEQUENCES
BUT, IF YOU ASK ME …
Credits to…Dr. Koch
Dr. Temmerman
Dr. Sarens
Dr. Pannier
Dr. Mignolet
Aafke
Annelies
Pascal
Chris
Serge
Stefaan
MiraDavid
Kathleen
AstridSofie
VickyMarc
Gudrun
HelenaMarijke
Kelly
Thijs
Paul
CindyChloé
Mieke
Karen
Guido
Sonja
Evelien
Leen
MarijkeV
Hendrik Dr. Swinnen
Maria
RitaMariaken
Marlies