Form - Ienvironmentclearance.nic.in/writereaddata/Online/... · Name of the Project/s BENZO CHEM...

0

FORM -I

For

PROPOSED EXPANSION OF SPECIALTY CHEMICALS & PESTICIDE

INTERMESDIATE PRODUCTS IN EXISTING UNIT

of

M/s. BENZO CHEM INDUSTRIES PVT. LTD.

Plot No. Z-103/D, PHASE –II, DAHEJ SEZ,

Taluka: Vagra, Dist: Bharuch-392 130,

Gujarat.

Prepared By:

1

FORM – I

(I) Basic Information

Sr.

No.

Item Details

1. Name of the Project/s BENZO CHEM INDUSTRIES PVT. LTD.

2. S. No. in the Schedule 5(f) & 5(b)

3. Proposed capacity/area/length/tonnage to

be handled/command area/lease

area/number of wells to be drilled

List of Products and their capacity is given as

Annexure -I.

Total plot area: 47613.19 m2. No bore well to

be drilled within the premises.

4. New/Expansion/Modernization Expansion

5. Existing capacity/area etc. Existing Production Capacity = 600 MT/Month

6. Category of project i.e. ‘A’ or ‘B’ ‘A’

7. Does it attract the general condition? If yes,

please specify.

-

8. Does it attract the specific condition? If yes,

please specify.

-

9. Location Dahej SEZ-II Area, Dahej, Taluka: Vagra, Dist:

Bharuch, Gujarat.

Plot/Survey/Khasra No. Plot. No. Z/103/D

Village Dahej SEZ-II

Tehsil Vagra

District Bharuch

State Gujarat

10. Nearest railway station/airport along with

distance in kms.

Nearest Railway Station : Bharuch: 50 km

Nearest Airport: Baroda: 100 km

11. Nearest Town, city, District Headquarters

along with distance in kms.

Nearest town: Bharuch : 50 km, Nearest

District Head quarter: Bharuch : 50 km

12. Village Panchayats, zilla parishad, Municipal

corporation, Local body (Complete postal

addresses with telephone nos. to be given)

Luvara, Taluka: Vagra, Dist. Bharuch – 392

130, Gujarat

13. Name of the applicant M/s. BENZO CHEM INDUSTRIES PVT. LTD.

14. Registered address Plot. No. Z/103/D, Dahej SEZ-II, Tal: Vagra,

Dist: Bharuch.

15. Address for correspondence: M/s. BENZO CHEM INDUSTRIES PVT. LTD.

26-28-A, Cawasji Patel Street, Fort, Mumbai

Name Mr. Sunil Nawal

2

Designation (Owner/Partner/CEO) Director

Address M/s. Benzo Chem Industries Pvt. Ltd.

26-28-A, Cawasji Patel Street, Fort, Mumbai

Pin Code 400001

E-Mail [email protected]

Telephone No. +91-22-43555851 / Mobile: +919892203750

Fax No. +91-22-40057327

16. Details of Alternative Sites examined, if any

location of these sites should be shown on

a topo sheet.

No

17. Interlinked Projects No

18. Whether separate application of

interlinked project has been submitted?

No interlinked project

19. If Yes, date of submission Not applicable

20. If no., reason Not applicable

21. Whether the proposal involves

approval/clearance under: If yes, details of

the same and their status to be given.

(a) The Forest (Conservation) Act, 1980?

(b) The Wildlife (Protection) Act, 1972?

(c) The C.R.Z Notification, 1991?

Not applicable, as the project is located in

Dahej SEZ-II.

22. Whether there is any Government

order/policy relevant/relating to the site?

No

23. Forest land involved (hectares) NA

24. Whether there is any litigation pending

against the project and/or land in which

the project is propose to be set up?

(a) Name of the Court

(b) Case No.

(c) Orders/directions of the Court, if any

and its relevance with the proposed

project.

No

• Capacity corresponding to sectoral activity (such as production capacity for

manufacturing, mining lease area and production capacity for mineral production, area

for mineral exploration, length for linear transport infrastructure, generation capacity for

power generation etc.,)

3

(II) Activity

1. Construction, operation or decommissioning of the Project involving actions, which

will cause physical changes in the locality (topography, land use, changes in water

bodies, etc.)

Sr.

No.

Information/Checklist confirmation Yes

/No?

Details thereof (with approximate

quantities / rates, wherever possible)

with source of information data

1.1 Permanent or temporary change in land

use, land cover or topography including

increase in intensity of land use (with

respect to local land use plan)

No Proposed expansion is within the

existing Dahej SEZ.

1.2 Clearance of existing land, vegetation and

buildings?

Yes Minor site clearance activities shall be

carried out to clear shrubs and weed to

conduct soil survey and initial

preparation.

1.3 Creation of new land uses? No Land is for industrial purpose.

1.4 Pre-construction investigations e.g. bore

houses, soil testing?

Yes Soil testing and analysis will be done for

detailed engineering before

construction.

1.5 Construction works? Yes The construction work includes process

plants, utility blocks & other

infrastructure which will be in different

stages. Plant layout is given as

Annexure – II.

1.6 Demolition works? No

1.7

Temporary sites used for construction

workers or housing of construction workers?

No

1.8 Above ground buildings, structures or

Earthworks including linear structures, cut

and fill or excavations

Yes All the process plants will have

structures & will require excavation.

Other buildings, godown, stores, tank

farms, weigh bridges, etc. also require

some excavations work. Plant layout is

given as Annexure – II.

1.9

Underground works including mining or

tunneling?

No

1.10 Reclamation works? No

1.11 Dredging? No

1.12 Offshore structures? No

4

1.13 Production and manufacturing Yes Manufacturing process, Chemical

Reaction and Mass Balance is given as

Annexure –III.

1.14 Facilities for storage of goods or materials? Yes Raw material storage area, Tank farm

area & finished products area will be

developed for proposed project.

1.15

Facilities for treatment or disposal of solid

waste or liquid effluents?

Yes Full Fledged Effluent Treatment Plant

and MEE will be installed to treat the

effluent so as to achieve the GPCB

norms.

The treated effluent shall be drained

into underground pipe line of SEZ.

MEE Condensate will be reused for

cooling purpose.

The MEE Salt will be disposed off in the

approved TSDF site.

Domestic Waste water will be disposed

in biological treatment of ETP or by

septic tank/soak pit.

Hazardous waste shall be disposed to

approve TSDF Site.

Details of water consumption &

wastewater generation are given as

Annexure IV.

Details of proposed Effluent Treatment

Plant, and proposed MEE system to be

installed are attached as Annexure V.

Details of Hazardous waste generation

and disposal is attached as Annexure VI.

1.16

Facilities for long term housing of

operational workers?

No Local operational staff of about 50

people shall be employed for the

proposed plant.

1.17 New road, rail or sea traffic during

construction or operation?

No The project is ideally situated in Dahej

SEZ-II, Dahej. It is having well

connectivity of Road as well as Railways.

It is well accessible by Road transport

and The National Highway is 50 K.M.

away from the project site and State

Highway is 5 Km.

1.18 New road, rail, air waterborne or other

airports etc?

No

5

1.19 Closure or diversion of existing transport

routes or infrastructure leading to changes

in traffic movements?

No

1.20 New or diverted transmission lines or

pipelines?

No

1.21

Impoundment, damming, converting,

realignment or other changes to the

hydrology of watercourses or aquifers?

No

1.22 Stream crossings? No

1.23

Abstraction or transfers or the water form

ground or surface waters?

Yes No ground water shall be used. The raw

water shall be supplied by Dahej SEZ-II/

GIDC authority.

1.24

Changes in water bodies or the land surface

affecting drainage or run-off?

No Site is located in Dahej SEZ-II, Dahej.

There is no water body within the

proposed project premises.

Storm water drainage shall be provided

& diverted to existing natural storm

water drain.

1.25

Transport of personnel or materials for

construction, operation or

decommissioning?

Yes Transportation of personnel or raw

material and products will be primarily

by road only.

1.26 Long-term dismantling or decommissioning

or restoration works?

No There is no dismantling of any sort. Not

applicable.

1.27 Ongoing activity during decommissioning

which could have an impact on the

environment?

No Not applicable as no decommissioning is

required.

1.28

Influx of people to an area in either

temporarily or permanently?

No This is a well developed Industrial Area

and due to project, 50 people shall be

employed.

Not applicable.

1.29 Introduction of alien species? No Not applicable.

1.30 Loss of native species of genetic diversity? No Not applicable.

1.31 Any other actions? No Not applicable.

6

2. Use of Natural resources for construction or operation of the Project (such as land,

water, materials or energy, especially any resources which are non-renewable or in short

supply):

Sr.

No

Information/checklist confirmation Yes/

No?

Details there of (with approximate

quantities/rates, wherever possible)


2.1 Land especially undeveloped or agriculture

land (ha)

No Proposed expansion is within the

existing Dahej SEZ.

2.2 Water (expected source & competing

users) unit: KLD

Yes Water Source: GIDC Water Supply - 630

KLD

2.3 Minerals (MT) No --

2.4

Construction material -stone, aggregates,

sand / soil (expected source MT)

Yes Material Qty. Source

Bricks 1614000 no. From

local

supply

Cement 207000Bags

Sand 67000 m3

TMT Steel 2250 MT

Kapchi 83160m3

2.5 Forests and timber (source - MT) No --

2.6

Energy including electricity and fuels

)source, competing users) Unit: fuel (MT),

energy (MW)

Yes Power required from MGVCL

1500 KVA (Existing)

4100 KVA(Proposed)

5600 KVA (Total)

Stand by power supply from

D.G. set – Existing: 500 KVA

D.G. Set - Proposed -1000 KVA

Total - 1500 KVA (D.G.Set)

Fuel:

Existing:

Natural gas: 15000 m3/day

Coal 40.0 MT/Day

HSD: 300 Lit/Day

Proposed:

Coal 40.0 MT/Day

HSD: 300 Lit/Day

Total:

Natural gas: 15000 m3/day

Coal 80.0 MT/Day

HSD: 600 Lit/Day

2.7 Any other natural resources (use

appropriates standard units)

No Not applicable

7

3. Use, storage, transport, handling or production of substances or materials, which could

be harmful to human health or the environment or raise concerns about actual or

perceived risks to human health.

Sr.

No.

Information / Checklist confirmation Yes/

No?


quantities / rates wherever possible)


3.1 Use of substances or materials, which are

hazardous (as per MSIHC rules) to human

health or the environment (flora, fauna,

and water supplies)

Yes

List of Hazardous Chemical with

storage, Handling and Control

measures are given as Annexure: VIII

3.2 Changes in occurrence of disease or affect

disease vectors (e.g. insect or water borne

diseases)

No

3.3 Affect the welfare of people e.g. by

changing living conditions?

No

3.4

Vulnerable groups of people who could be

affected by the project e.g. hospital

patients, children, the elderly etc.,

No

3.5 Any other causes No

4. Production of solid wastes during construction or operation or decommissioning

MT/month)

Sr.

No.

Information/Checklist confirmation Yes/

No?




4.1 Spoil, overburden or mine wastes No

4.2

Municipal waste (domestic and or

commercial wastes) No

4.3

Hazardous wastes (as per Hazardous Waste

Management Rules)

Yes Please refer Annexure VI

4.4 Other industrial process wastes Yes Please refer Annexure VI

4.5 Surplus product Yes Please refer Annexure VI

4.6

Sewage sludge or other sludge from

effluent treatment

No

4.7 Construction or demolition wastes Yes Construction waste shall be utilized for

leveling, land filling in the premises.

4.8 Redundant machinery or equipment No

4.9 Contaminated soils or other materials No

4.10 Agricultural wastes No

4.11 Other solid wastes Yes Please refer Annexure VI

8

5. Release of pollutants or any hazardous, toxic or noxious substances to air (Kg/hr)

Sr.

No.

Information/Checklist confirmation Yes/N

o


quantities/rates, wherever possible) with

source of information data

5.1 Emissions from combustion of fossil fuels

from stationary or mobile sources

Yes Please refer Annexure – VII.

5.2 Emissions from production processes Yes Please refer Annexure – VII.

5.3 Emissions from materials handling

storage or transport

Yes The construction materials such as stones,

cements, bricks & coal may pollute the air

by dust particles. But it will be controlled

by covering the trucks & trailers by clothes

during transportation. Also all the

hazardous chemicals storage tanks will be

provided with flame arrestors & breather

valves for safety.

5.4 Emissions from construction activities

including plant and equipment

Yes During construction work, the Nearby

buildings area will be covered by sheets

or clothes to avoid dust contamination in

air.

5.5 Dust or odors from handling of materials

including construction materials, sewage

and waste

Yes Adequate measures will be taken to

control emissions of dust.

5.6 Emissions from incineration of waste No

5.7 Emissions from burning of waste in open

air e.g. slash materials, construction

debris)

No

5.8 Emissions from any other sources No

6. Generation of Noise and Vibration, and Emissions of Light and Heat:

Sr.

No.


No


Quantities /rates, wherever possible)

With source of source of information

data

6.1

From operation of equipment e.g.

engines, ventilation plant, crushers

Yes Boiler, vacuum pump. Adequate

measures will be taken by the unit. The

noise level will be within the prescribed

limit.

6.2 From industrial or similar processes Yes -do-

6.3 From construction or demolition No

6.4 From blasting or piling No

6.5 From construction or operational traffic No

9

6.6 From lighting or cooling systems No

6.7 From any other sources No

7. Risks of contamination of land or water from releases of pollutants into the ground or

into sewers, surface waters, groundwater, coastal waters or the sea:

Sr.

No


No?




7.1

From handling, storage, use or spillage of

hazardous materials

Yes All the raw material shall be stored

separately in designated storage area

with necessary safely precautions.

Bund walls shall be provided around

raw materials storage tanks for

containing any liquid spillage.

Other materials shall be stored in bags

/ drums on pallets with concrete

flooring and no spillage is likely to

occur. Please refer Annexure –VIII.

7.2

From discharge of sewage or other

effluents to water or the land (expected

mode and place of discharge)

No Sewage effluent shall be treated in

secondary treatment of ETP or septic

tank/soak pit.

7.3

By deposition of pollutants emitted to air

into the land or into water

No The factory is located in Dahej SEZ-II

Dahej. The emissions shall conform to

the GPCB / CPCB norms of discharge.

The treated effluent shall be drained

into underground pipe line of SEZ for

final discharge into deep sea.

7.4 From any other sources No Not applicable

7.5 Is there a risk of long term build up of

pollution in the environment from these

sources?

No

Full- fledged Environmental

Management System (EMS) will be

installed. i.e. ETP, Air Pollution Control

systems, Hazardous Waste Handling

and Management as per norms, etc.

which will eliminates the possibility of

building up of pollution.

10

8. Risks of accident during construction or operation of the Project, which could affect

human health or the environment:

Sr.

No

Information/Checklist confirmation

Yes/

No?




8.1 From explosions, spillages, fires etc

from storage, handling, use or

production of hazardous substances

Yes Please refer Annexure – VIII.

8.2 From any other causes No Not applicable

8.3 Could the project be affected by natural

disasters causing environmental

damage (e.g. floods, earthquakes,

landslides, cloudburst etc)?

No There is no history of flood in Dahej SEZ-II,

Dahej.

The buildings are designed considering

seismic zone III. The land is plain terrain –

no scope of landslide.This area is having

moderate rainfall and there is no history

of cloudburst.

9. Factors which should be considered (such as consequential development) which could lead

to environmental effects or the potential for cumulative impacts with other existing or

planned activities in the locality

Sr.

No.


No?




9.1 Lead to development of supporting.

laities, ancillary development or

development stimulated by the project

which could have impact on the

environment e.g.:

* Supporting infrastructure (roads, power

supply, waste or waste water treatment,

etc.)

• housing development

• extractive industries

• supply industries

• other

No Site is located in Dahej SEZ-II, Dahej,

having the entire required

infrastructure.This industrial zone is

having existing road infrastructure,

power supply are to be utilized.

Local people will be employed and no

housing is required. Please refer

Annexure – IX.

9.2

Lead to after-use of the site, which could

have an impact on the environment

No --

9.3 Set a precedent for later developments No --

9.4 Have cumulative effects due to proximity

to Other existing or planned projects with

similar effects

No

--

11

(III) Environmental Sensitivity

Sr.

No

Information/Checklist confirmation Name /

Identity

Aerial distance (within 25 km). Proposed

Project Location Boundary.

1 Areas protected under international

conventions national or local legislation for

their ecological, landscape, cultural or other

related value

No Site is located in Dahej SEZ 2, Dahej, Dist.

Bharuch, Gujarat.

2 Areas which are important or sensitive for

Ecological reasons - Wetlands, watercourses

or other water bodies, coastal zone,

biospheres, mountains, forests


Bharuch, Gujarat.

Forest area of Rajpipla is 100 km away.

3 Areas used by protected, important or

sensitive species of flora or fauna for

breeding, nesting, foraging, resting, over

wintering, migration


Bharuch, Gujarat.

4 Inland, coastal, marine or underground

waters

Yes Arabian Sea- 2.5 Km

River Narmada- 3.0 Km

5 State, National boundaries No --

6 Routes or facilities used by the public for to

recreation or other tourist, pilgrim areas.

No Not applicable

7 Defense installations No NIL

8 Densely populated or built-up area Yes Bharuch city – 2 lakh population

9 Areas occupied by sensitive man-made land

community facilities)

No Site is located in Dahej SEZ II, Dahej,

Dist.Bharuch, Gujarat.

10 Areas containing important, high quality or

scarce resources (ground water resources,

surface resources, forestry, agriculture,

fisheries, tourism, tourism, minerals)

Yes

The project shall not use ground water.

The treated effluent shall be drained into

underground pipe line of SEZ and finally

discharged into deep sea.

The project being in notified industrial area

does not affect agricultural land.

No tourist location in the vicinity of 50 Kms.

11 Areas already subjected to pollution or

environmental damage. (those where existing

legal environmental standards are exceeded)

No Site is located in Dahej SEZ 2, Dahej,

Dist.Bharuch, Gujarat.

12

Areas susceptible to natural hazard which

could cause the project to present

environmental problems (earthquakes,

subsidence, landslides, erosion, flooding or

extreme or adverse climatic conditions)

No

IV). Proposed Terms of Reference for EIA studies: Please refer Annexure – X.

12

“ I hereby given undertaking that the data and information given in the application and

enclosures are true to my best knowledge and belief and I am aware that if any part of the

data and information submitted is found to false or misleading at any stage, the project will

be rejected and clearance give, if any to the project will be revoked at our risk and cost”.

Date: 18/11/2017

Place: Mumbai

Signature of the applicant

MR. PAWAN DEORA

26/28-A, Cawasji Patel street,

Fort, Mumbai 400 001.

Director (Project Proponent/ Authorized Signatory)

NOTE:

1. The projects involving clearance under Coastal Regulation Zone Notification, 1991 shall

submit with the application a C.R.Z map duly demarcated by one of the authorized agencies,

showing the project activities, w.r.t. C.R.Z (at the stage of TOR) and the recommendations of

the State Coastal Zone Management Authority (at the stage of EC). Simultaneous action shall

also be taken to obtain the requisite clearance under the provisions of the C.R.Z Notification,

1991 for the activities to be located in the CRZ.

2. The projects to be located within 10 km of the National Parks, Sanctuaries, Biosphere

Reserves, Migratory Corridors of Wild Animals, the project proponent shall submit the map

duly authenticated by Chief Wildlife Warden showing these features vis-à-vis the project

location and there commendations or comments of the Chief Wildlife Warden thereon (at the

stage of EC).

3. All correspondence with the Ministry of Environment & Forest including submission of

application for TOR/Environmental Clearance, subsequent clarifications, as may be required

from time to time, participation in the EAC Meeting on behalf of the project proponent shall

be made by the authorized signatory for the specific project

13

LIST OF ANNEXURES

SR. NO. NAME OF ANNEXURE

I List of Products with their Production Capacity

II Layout of Plant

III Brief Manufacturing Process Description

IV Details of water consumption & waste water generation

V Description of Effluent Treatment Plant

VI Details of Hazardous Waste Generation and Disposal

VII Details of Stacks and Vents

VIII Details of Hazardous Chemicals Storage & Handling

IX Socio-economic Impacts

X Proposed Terms of Reference for EIA studies

XI Plot allotment letter of GIDC

XII GIDC's water supply letter

XIII GIDC's drainage connection letter

XIV Common TSDF & CHWIF's membership certificate

XV Toposheet

14

Annexure – I

List of Products & Raw Materials and Their Capacity

Sr.

No.

Name of Products CAS No. Quantity as per

EC No. F. No. J-

11011/132/201

4-IA II (I) and

CTE No. 70398

Change Quantity after

proposed

expansion

LD50

(MT / Month)

1. 2-Amino Benzo Nitrile 1885-29-6 10 -9 1 80 mg/kg,

2. 2-Amino-5-Bromo Benzo

Nitrile

39263-32-

6

5 -5 0 -----

3. 2,4,6-trimethyl

Benzaldehyde

(Mesitaladehyde ) / or

2,4,6-

TrimethylBenzaldehyde

84%in 16% Aceton

(Mesitaladehyde 84% in

16% Acetone)

487-68-3 20 -12 8 3

mg/kg,Oral

,

4 Indoline 496-15-1 20 -20 0 238 mg/kg,

5 2,4-Dichloro Phenyl Acetic

Acid

19719-28-

9

25 -25 0 -----

6 2,4-Dichloro Phenyl Acetyl

Chloride

53056-20-

5

25 -12 13 Acute >

5000

mg/kg.

7 2,4,6-Trimethyl Phenyl

Acetyl Chloride

52629-46-

6

20 +5 25 4400

mg/kg.

8 2,4 Dichloro Meta Cresol 17788-00-

0

4 -3 1 > 3200

mg/kg

9 Pivolonitrile

(Trimethylacetonitrile )

630-18-2 10 -10 0 -----

10 4,4-dihydroxy Benzo

phenone

611-99-4 25 -25 0 500 mg/kg,

11 2-chloro-4,6 dimethoxy-

1,3,5-Triazine

3140-73-6 25 0 25 ---

12 2-Coumaranone 30%,Acetic

Anhydride70 %

553-86-6 170 +38 208 2,000

mg/kg

15

Sr.

No.


EC No. F. No. J-

11011/132/201

4-IA II (I) and

CTE No. 70398

Chang Quantity

after

proposed

expansion

LD50

(MT / Month)

13. 4-Bromo-2-Hydroxy

Anisole / 5-Bromo-2-

Methoxy Phenol

37942-01-1 4 -4 0 --

14. 5-Propionyl-2-Thiophenyl

acetic acid (PPP) /

103918-73-

6

2 -2 0 8 mg/kg

2-Phenyl Thio-5-

Propionyl Phenyl Acetic

Acid

92321-29-4 --

15. 2,3,4,5-tertrachloro

Benzoyl chloride

42221-52-3 17 -17 0 --

16. 3,4,5 trimethoxy Toluene 6443-69-2 25 -17 8 --

17. 3,4,5 trimethoxy Benzyl

chloride

3840-30-0

2 -2 0 --

18. 3,4,5-trimethoxybenzyl

cyanide

13338-63-1 2 -2 0 56 mg/kg

19. 3,4,5-trimethoxyphenyl

acetic acid

951-82-6

2 -2 0 --

20. 3,4,5-trimethoxy benzoic

acid

118-41-2 4 -3 1 2100 mg/kg

21. 3,4,5-Trimethoxy

Benzaldehyde

86-81-7

17 -17 0 422 mg/kg

22. 4,4-dimethoxy-2-

Butanone

5436-21-5

17 -17 0 6200 mg/kg

23. R-2-(2,4-

Dichlorophenoxy)

Propionic Acod

15165-67-0 40 -40 0 825 mg/kg

24. Para Methyl

Benzaldehyde / 4-Methyl

Benzaldehyde

104-87-0

25 -25 0 400 mg/kg

25. 2-5 Dimethyl Phenyl

Acetyl Chloride

55312-97-5 25 +8 33 --

26. 2-Amino 2 Phenyl Butyric

Acid

5438-07-3

4 -4 0 --

16

Sr.

No.


EC No. F. No. J-

11011/132/201

4-IA II (I) and

CTE No. 70398

Chang Quantity

after

proposed

expansion

LD50

(MT / Month)

27. 1-(2,6 Dichloro Phenyl)2-

Indolinone

15307-86-5

4 -4 0 170 mg/kg

28. 2-(3-Benzoyl Phenyl)-

propio Nitrile /

Ketoprofen Nitrile

42872-30-0

8 -8 0 483 mg/kg

29. N-Methyl-1-Naphtahlene

Methyl Amine Acetate

------- 2 -- 2 --

30. N-Methyl-1-Naphtahlene

Methyl Amine Base

14489-75-9 2 -- 2 --

31. Para Chloro Phenyl Ethyl

Amine / 2-(4-Chloro-

Phenyl)-Ethylamine

156-41-2

5 -5 0 --

32. Ortho Chloro Phenyl

Ethyl Amine

13078-80-3 5 -5 0 --

33. 2-Dimethylamino-

2Phenyl Butanol/2-(N,N-

Dimethylamino)-2-

Phenyl-1-Butanol

39068-94-5

4 -4 0 --

34. Methyl- 2-

Dimethylamino-2- Phenyl

butyrate /2-(N,N-

Dimethyl Amino)-2-

Phenyl-2-Butyrate

39068-93-4

4 -4 0 --

35. 2-Phenyl Butyric Acid 90-27-7

4 -4 0 --

36. 5-Chloro-2-Hydroxy

Benzo phenone

85-19-8

5 -4 1 980 mg/kg

37. 5-(1- Carboxy Ethyl)-2-

Phenyl Thiophenyl Acetic

Acid (DIACID)

83237-49-4

2 -2 0 --

38. N-Methyl 1-Napthalene

Methyl Amine

Hydrochloride

65476-13-4 5 -2 3 --

39. 7-Methoxy 1 Tetralone 6836-19-7

5 -5 0 --

17

Sr.

No.


EC No. F. No. J-

11011/132/201

4-IA II (I) and

CTE No. 70398

Chang Quantity

after

proposed

expansion

LD50

(MT / Month)

40. 2-Amino 4 Hydroxy

Acetophenone

19745-72-3 0 +3 3 --

41. 3-coumaranone 7169-34-8 0 +8 8 --

42. 3, 3 Dimethyl Butyrl

Chloride

7065-46-5 0 +16 16 277 mg/kg

43. 4-bromo Anisole 104-92-7 0 +16 16 2200 mg/kg

44. 4-Cyano Benzoic Acid 619-65-8 0 +1 1 2000 mg/kg

45. 7-Hydroxy 1 Tetralone 22009-38-7 0 +1 1 --

46. Atropic acid 492-38-6 0 +2 2 300 mg/kg

47. 4-chloro Benzaldehyde

Glycol Acetal

2403-54-5 0 +6 6 240 mg/kg

48. 2,2-Dichloro-2 Phenyl

Acetic Acid Ethyl Ester

5317-66-8 0 +16 16 6000 mg/kg

49. Para Chloro Meta Xylenol

BP

88-04-0 0 +25 25 3830 mg/kg

50. Pivaloacetonitrile 59997-51-2 0 +3 3 283 mg/kg

51. 3-Chloro2- Methyl

Anisole

3260-88-6 0 +25 25 2000 mg/kg

52. 2-Dimethyl 2 Methyl 1

Propanol

75-84-3 0 +8 8 1506 mg/kg

53. 4-Hydroxy 3 5 Dimethyl

Benzaldehyde

2233-18-3 0 +2 2 2000 mg/kg

54. 2 Ethyl 2 Methyl Butanoic

Acid

19889-37-3 0 +8 8 500 uL/kg

55. 2 2 Dimethyl Butyrl

Chloride

5856-77-9 0 +8 8 --

56. DV Acid Chloride (60:40

Cistrans)

52314-67-7 0 +5 5 575 mg/kg

57. Ortho Benzyl Para Chloro

Phenol

120-32-1 0 +7 7 65 mg/kg

58. 4-Isopropyl Catechol 2138-43-4 0 +1 1 56 mg/kg

59. 1-Adamantyl HCL 665-66-7 0 +8 8 800 mg/kg

60. 1-Bromo-2-(3-Chloro-4-

Ethoxyphenyl)-2-Methyl

Propane

0 +11 11 --

18

Sr.

No.


EC No. F. No. J-

11011/132/201

4-IA II (I) and

CTE No. 70398

Chang Quantity

after

proposed

expansion

LD50

(MT / Month)

61. 4-Chloro 2,6 Dimethyl

Phenyl Acetic Acid

39944-18-8 0 +8 8 2000 mg/kg

62. 4-Hydroxy Benzyl Alcohol 623-05-02 0 +3 3 10500 mg/kg

63. 2-Methoxy Phenyl

Acetone

5211-62-1 0 +1 1 3330 mg/kg

64. Methyl-2-Dimethyl

Amino-2-phenyl butyrare

39068-93-4 0 +2 2 --

65. Meta Phenoxy Benzyl

Alcohol

13826-35-2 0 +4 4 2040 mg/kg

66. 4-Bromophenyl Acetic

Acid Methyl Ester

41841-16-1 0 +1 1 2000 mg/kg

67. N Methyl 1-Napthalene

Methyl Amine Hydro

Chloride

65473-13-4 0 3 3 --

67. 4-Hydroxy Acetophenone 99-93-4 0 +16 16 1500 mg/kg

68. 2-(1-Admantyl)-4-Bromo

Anisole

104224-63-

7

0 +2 2 3200 mg/kg

69. 2-(3-Hydroxy-2-Methyl

Propionyl)-aminol-2-

methyl-propanol

-- 0 +10 10 --

70 4-Bromophenyl Acetic

Acid

1878-68-8 0 +1 1 1050 mg/kg

71 2-Amino 2-Methyl

Propanol

124-68-5 0 +12 12 --

72 2-Bromo-5-Methoxy-

Benzoic Acid

22921-68-2 0 +4 4 2900 mg/kg

73 2-Bromo-5-Hydroxy -

Benzoic Acid

58380-11-3 0 +4 4 --

74 Diphenylmethane-bis-

4,4’-N,N’-ethylene Urea

(DEU)

7417-99-4 0 +8 8 2000 mg/kg

75 TrimethylolpropaneTris(2

-methyl-1-

aziridinepropionate)

64264-57-2 0 +8 8 2000 mg/kg

76 PentaerythritolTris([3-(1-

aziridinyl)propionate]

57116-45-7 0 +8 8 4.92 mg/kg

77 2-Bromophenyl 194727-74- 0 +1 12 --

19

Sr.

No.


EC No. F. No. J-

11011/132/201

4-IA II (I) and

CTE No. 70398

Chang Quantity

after

proposed

expansion

LD50

(MT / Month)

Acetonitrile 3

78 Phenyl Acetic Acid Ethyl

Ester

101-97-3 0 +8 8 3300 mg/kg

79 3-Methoxy,2-Methyl

Benzoyl Chloride

24487-91-0 0 +8 8 --

80 Methyl(E)-3-methoxy-2-

(2-chloromethylphenyl)-

2-propenoate

11742-51-0 0 +33 33 --

81 2-(2-hydeoxyphenyl)-3-

methoxypropenoic acid

methyl ester

125808-20-

0

0 +33 33 --

82 Methyl (2E) -2-( 2-(6-(2-

Cyanophenoxy

)Pyrimidine -4yl)Oxy )

Phenyl Acetate

47841-45-5 0 +33 33 --

83 3-CHLORO-4-

METHYLISOPROPYL

BENZOATE

-- 0 +25 25 2000 mg/kg

Total 600 144 744

20

LIST OF BY–PRODUCTS

Sr.

No.

List of By product Existing

quantity as

per EC

(MT/Month)

Generated from Products Proposed

quantity after

expansion

(MT / Month)

1. HCl (30%) 126 2-Amino Benzo Nitrite,

2,4-Dichloro Phenyl

Acetyl Chloride, 2,4,6-

Trimethyl Phenyl Acetyl

Chloride,2,5-Dimethyl

Phenyl Acetyl Chloride, 5-

Chloro-2-Hydroxy Benzo

Phenone, 3 3 Dimethyl

Butyrl Chloride, 7-

Hydroxy 1 Tetralone, 2,2-

Dichloro-2-ohenyl Acetic

Acid Ethyl Ester, Para

Chloro Meta Xylenol BP,

Pivalacetonitrile, 2,2

Dimethyl Butyrl Chloride,

DV Acid Chloride, Ortho

Benzyl Para Chloro

Phenol, 1-Admantyl HCL,

Meta Phenoxy Benzyl

Alcohol, 4-Hydroxy

Acetophenone, 4-Bromo

Phenyl Acetic Acid./

Diphenylmethane-bis-


(DEU)/

TrimethylolpropaneTris(2-

methyl-1-

aziridinepropionate) /

PentaerythritolTris([3-(1-

aziridinyl)propionate]/ 2-

Bromo-5-Hydroxy –

Benzoic Acid

156

2. H2SO4 (70%) 50 --- 20

3. Liquor Ammonia

(22-24% solution)

45 2-Coumaronone 30%,

Acetic Anhydride,

Pivaloacetonitrile, 2,2

Dimethyl Butyrl Chloride,/

4-Bromo Phenyl Acetic

55

21

Acid

4. HBr

(35-40% Solution)

70 3,4,5 Trimethoxy toluene,

3,4,5- Trimethoxy benzoic

acid/ ester/2-Bromo-5-

methoxy-benzoic Acid/ 2-

Bromo-5-hydroxy-benzoic

Acid

70

5. NaBr

(18-20% Solution)

76 3,4,5 Trimethoxy toluene,

3,4,5- Trimethoxy benzoic

acid/ ester, 4-Bromo

Anisole,/ 2-Bromophenyl

Acetonitrile/ 4-Bromo

Phenyl Acetic Acid

76

6. Phosphoric Acid (30-

35% Solution)

60 7-Hydroxy 1 Tetralone 60

7. Copper Sulphate /

Copper Hydroxide /

Copper Oxidize

80 2-Coumaranone 30%,

Acetic Anhydride 70%

40

8. Sodium Chloride 80 Methyl(E)-3-methoxy-2-

(2-chloromethylphenyl)-

2-propenoate

60

9. Sodium Sulphate 60 -- 00

10. Sodium Acetate 5 -- 00

11. Sodium

SulfiteSolution(18-

20%) or Sodium

Bisulfite Solution

(18-20%)

30 2,4-Dichloro phenyl acetyl

chloride, 2,4,6-Trimethyl

phenyl acetyl chloride,

3,4,5-Trimethoxy Benzoic

Acid/ ester, 2-5 Dimethyl

phenyl acetyl chloride,

3,3 Dimethyl Butyrl

Chloride, 2,2-Dichloro-2

phenyl acetic acid ethyl

ester, 2,2 Dimethyl butyrl

chloride, D V acid

Chloride,

Diphenylmethane-bis-


(DEU)/

TrimethylolpropaneTris(2-

methyl-1-

aziridinepropionate) /

PentaerythritolTris([3-(1-

aziridinyl)propionate]/ 3-

60

22

Methoxy,2-Methyl

Benzoyl Chloride

12. Potassium Chloride 5 -- 0

13. Potassium

Carbonate

12 -- 12

14. Ammonium

Sulphate

4 -- 0

15. Mix Chloro Xylenol 0 Para Chloro Meta Xylenol

BP

6

16. 2-Hydroxy

Acetophenone

0 4-Hydroxy Acetophenone. 1

17. Methanol 50% 0 2-Chloro-4,6 Dimethoxy-

1,3,5-Triazine.

40

18 Poly Aluminium

Chloride Solution

25%

0 2,4-Dichloro Meta Cresol,

%-Chloro-2-Hydroxy

Benzo Phenone, 2-Amino-

4-Hydroxy

Benzophenone, 7-

Hydroxy 1 Tetralone,

Meta Phenoxy Benzyl

Alcohol, 4-Hydroxy

Acetophenone,

20

23

List of Raw Materials and their capacity

Sr.

No.

Name of Products Quantit

y in

MT/

Month

Name of Raw

Materials

Quantity

in T/T

Quantity in

MT/Month

1.

2-Amino Benzo Nitrile

1

Toluene 0.42 0.42

Phosphorous

Penta chloride

2.60 2.60

Sodium

Hydroxide

1.50 1.50

2-

Aminobenzamide

1.54 1.54

Total 6.06 6.06

2.

2,4,6-Trimethyl

Benzaldehyde

(Mesitaladehyde ) /

2,4,6-Trimethyl

Benzaldehyde 84% in

16% Acetone

(Mesitaladehyde 84%

in 16% Acetone)

8

Mesitylene 0.84 6.72

Choral 1.13 9.07

Titanium

Tetrachloride

1.46 11.68

Soda Ash 0.67 5.38

Acetone 0.16 1.28

Tetra Ethyl

Benzyl

Ammonium

Chloride

0.01 0.08

Total 4.28 34.21

3.

2,4-Dichloro Phenyl

Acetyl Chloride

13

2,4-Dichloro

Phenyl Acetic

Acid / 2-4,

Dichloro Benzyl

Alcohol

1.10 14.30

Sodium

Hydroxide

0.48 6.24

Toluene 0.05 0.65

Thionyl Chloride 0.70 9.10

Total 2.33 30.29

4.

2,4,6-Trimethyl

Phenyl Acetyl

Chloride

25

2,4,6-Trimethyl

Phenyl Acetic

Acid / Mesitylene

1.06 26.50

Toluene 0.08 2.00


Sodium

Hydroxide

0.53 13.25

Total 2.54 63.50

24

Sr.

No.


y in

MT/

Month

Name of Raw

Materials

Quantity

in T/T

Quantity in

MT/Month

5.

2,4-Dichloro Meta

Cresol

1

2-Tert-Butyl-5-

Methyl Phenol

1.00 1.00

Sodium

Hydroxide

0.60 0.60

Aluminum

Chloride

0.40 0.40

Toluene 0.10 0.10

Chlorine Gas 0.30 0.30

HCL 30% 2.50 2.50

Total 4.90 4.90

6.

2-Chloro-4,6

Dimethoxy-1,3,5-

Triazine

25

Cyanuric Chloride 1.89 47.25

Methanol 0.70 17.50

Sodium Bi

Carbonate

2.00 50.00

Total 4.59 114.75

7.

2-Coumaranone 30%,

Acetic Anhydride 70 %

208

Ortho Chloro

Benzyl Cyanide

0.43 88.61

Caustic Soda Lye

48%

0.88 183.04

Toluene 0.08 15.60

HCL 30% 0.97 201.55

Copper Sulphate 0.03 6.03

Acetic Anhydride 0.70 145.60

Total 3.08 640.43

8.

3,4,5 Trimethoxy

Toluene

8

Para Cresol 0.80 6.40

Hydro Bromic

Acid 48%

2.68 21.44

Hydrogen

Peroxide 50%

1.03 8.26

Methanol 1.03 8.20

Sodium Metal 0.36 2.88

Toluene 0.84 6.72

Copper Chloride 0.03 0.20

Dimethyl

Formamide

0.16 1.28

Sulphuric Acid 0.80 6.40

Total 7.72 61.78

9. 3,4,5-Trimethoxy 1 Para Cresol 0.80 0.80

25

Sr.

No.


y in

MT/

Month

Name of Raw

Materials

Quantity

in T/T

Quantity in

MT/Month

Benzoic Acid / Ester

Hydro Bromic

Acid 48%

2.69 2.69

Hydrogen

Peroxide 50%

1.03 1.03

Methanol 0.40 0.40

Sodium Metal 0.36 0.36

Toluene 0.84 0.84


Dimethyl

Formamide

0.16 0.16


Total 7.13 7.13

10.

2-5 Dimethyl Phenyl

Acetyl Chloride

33

2,5-Dimethyl

Phenyl Acetic

Acid

1.00 33.00


Toluene 0.05 1.65

Sodium

Hydroxide

0.57 18.81

Total 2.46 81.18

11.

N-Methyl 1-

Napthalene Methyl

Amine Acetate

2

Dimethyl

Formamide

0.08 0.15

Sodium Hydride

60% in Paraffin

0.28 0.57

N-Methyl

Formamide

0.52 1.05

1-Chloro Methyl

Naphthalene

1.05 2.09

Sulphuric Acid

98%

1.05 2.09

Caustic Soda Lye

48%

2.30 4.60

Acetic Acid 0.29 0.58

Toluene 0.32 0.65

Total 5.89 11.78

12.

N-Methyl 1-

Napthalene Methyl

Amine Base

2

Dimethyl

Formamide

0.09 0.17

Sodium Hydride

60% in Paraffin

0.32 0.64

26

Sr.

No.


y in

MT/

Month

Name of Raw

Materials

Quantity

in T/T

Quantity in

MT/Month

N-Methyl

Formamide

0.60 1.19

1-Chloro Methyl

Naphthalene

1.19 2.38

Sulphuric Acid

98%

1.19 2.38

Caustic Soda Lye

48%

2.62 5.23

Toluene 0.32 0.65

Total 6.32 12.64

13.

5-Chloro-2-Hydroxy

Benzo phenone

1

Para Chloro

Phenol

0.72 0.72

Ortho Dichloro

Benzene

0.05 0.05

Aluminium

Chloride

0.80 0.80

Benzoyl Chloride 0.85 0.85

HCL 30% 0.50 0.50

Methanol 0.07 0.07

Total 2.99 2.99

14.

2-Amino 4 Hydroxy

Acetophenone

3

3-Amino Phenol 1.05 3.15

Nitrobenzene 0.15 0.45

Acetyl Chloride 1.60 4.80

Sodium Sulphate 0.05 0.15

Aluminium

Chloride

1.72 5.16

HCL 30% 1.88 5.64

Soda Ash 0.10 0.30

Sodium

Methoxide

0.60 1.80

Toluene 0.09 0.27

Total 8.54 25.62

15.

3-coumaranone

8

Ethyl Chloro

Acetate

0.70 5.60

Potassium

Carbonate

0.70 5.60

Methyl Salicylate 0.70 5.60

Dimethyl 0.30 2.40

27

Sr.

No.


y in

MT/

Month

Name of Raw

Materials

Quantity

in T/T

Quantity in

MT/Month

Formamide

Sodium

Methoxide

0.80 6.40

Toluene 0.40 3.20

HCL 30% 2.70 21.6

Potassium

Hydroxide

0.55 4.40

Methanol 1.80 14.40

Carbon 0.05 0.40

Total 8.70 69.60

16.

3, 3 Dimethyl Butyrl

Chloride

16

1,1,2

Trichloroethane

1.97 31.52

Sodium

Hydroxide

1.18 18.91

Carbon 0.01 0.16

Ter. Butanol 0.74 11.79



Total 15.19 243.10

17.

4-bromo Anisole

16

Anisole 0.75 12.00

Bromine 0.70 11.20

Hydrogen

Peroxide ( 50%)

0.30 4.80

Sodium

Hydroxide

Solution

0.05 0.80

Sodium

ThioSulphate

0.05 0.80

Total 1.85 29.60

18.

4-Cyano Benzoic Acid

1

Para Chloro

Benzoic Acid

1.10 1.10

Sodium Cyanide 0.34 0.34

Potassium Iodide 0.11 0.11

Dimethyl

Formamide

0.17 0.17

Sodium

Hypochloride

0.10 0.10

Total 1.82 1.82

28

Sr.

No.


y in

MT/

Month

Name of Raw

Materials

Quantity

in T/T

Quantity in

MT/Month

19.

7-Hydroxy 1

Tetralone

1

Anisole 0.86 0.86

Ethylene

Dichloride

0.11 0.11

Aluminium

Chloride

1.93 1.93

Succinic

Anhydride

0.80 0.80

HCL 30% 2.05 2.05

Hydrazine

Hydrate 80%

0.29 0.29

Potassium

Hydroxide

0.40 0.40

Diethylene Glycol 0.04 0.04

Poly Phosphoric

Acid

0.66 0.66

Toluene 0.11 0.11

Total 7.26 7.26

20.

Atropic acid

2

Phenyl Acetic

Acid

0.97 1.93

Para

Formaldehyde

0.21 0.43

Potassium

Carbonate

0.98 1.96

HCL 30% 0.87 1.74

Toluene 0.18 0.36

TBAB ( Cat. ) 0.00 0.00

Total 3.21 6.43

21.

4-chloro

Benzaldehyde Glycol

Acetal

6

4-Chloro

Benzaldehyde

0.90 5.40

Toluene 0.06 0.36

Ethylene Glycol 0.43 2.58

Total 1.39 8.34

22.

2,2-Dichloro-2 Phenyl

Acetic Acid Ethyl Ester

16

Phenyl Acetic

Acid

0.90 14.40



Catalyst 0.01 0.14

Ethanol 0.40 6.40

29

Sr.

No.


y in

MT/

Month

Name of Raw

Materials

Quantity

in T/T

Quantity in

MT/Month

Total 2.51 40.14

23.

Para Chloro Meta

Xylenol BP

25

Meta Xylenol / 3-

5 Xylenol

1.00 25.00

HCL 30% 0.12 2.88

Cupric Chloride 0.01 0.25

Per Chloro

Ethylene

0.18 4.38

Chlorine 0.58 14.50

Total 1.88 47.00

24.

Pivaloacetonitrile

3

Pivaloyl Chloride 1.30 3.90

Methanol 0.35 1.05

Toluene 0.18 0.54

Acetonitrile 0.57 1.71

Sodamide 0.57 1.71

HCL 30% 1.42 4.27

Total 4.39 13.18

25.

3-Chloro2- Methyl

Anisole

25

2,6 Dichloro

Toluene

1.25 31.25

Dimethyl

Sulfoxide

0.35 8.75

Sodium

Methoxide

0.46 11.50

HCL 30% 0.22 5.50

Total 2.28 57.00

26.

2 Dimethylamino 2

Methyl 1 Propanol

8

Acetone 1.30 10.40


Methanol 2.60 20.80

Ammonium

Bicarbonate

1.50 12.00

HCL 30% 1.00 8.00

Sodium

Hydroxide

2.40 19.20

Sodium

Borohydride

0.55 4.40

Tetrahydro Furan 0.50 4.00

Para

formaldehyde

Solution

1.20 9.60

30

Sr.

No.


y in

MT/

Month

Name of Raw

Materials

Quantity

in T/T

Quantity in

MT/Month

Formic Acid 1.00 8.00

Total 13.35 106.80

27.

4-Hydroxy 3 5

Dimethyl

Benzaldehyde

2

2,6-Xylenol 1.00 2.00

Toluene 0.16 0.32


HexamethyleneT

etramine

1.16 2.32

Total 2.37 4.74

28.

2 Ethyl 2 Methyl

Butanoic Acid

8

2,2 Dimethyl

Butanol

0.85 6.80


Firmic Acid 0.75 6.00

Ice 1.00 8.00

Total 4.20 33.60

29.

2 2 Dimethyl Butyrl

Chloride

8

2-Methyl2-

Butanol

1.00 8.00

HCL 30% 2.50 20.00


Sodium

Hydroxide

0.40 3.20


Total 5.40 43.20

30.

DV Acid Chloride

(60:40 Cistrans)

5

D V Ester 1.05 5.25

Sodium

Hydroxide

1.38 6.88

Toluene 0.10 0.50



N-Methyl-2-

Pyrolidinine

0.0005 0.0025

Total 3.37 16.85

31.

Ortho Benzyl Para

Chloro Phenol

7

Benzyl Chloride 1.00 7.00

Para Chloro

Phenol

1.00 7.00

Toluene 0.10 0.70

Total 2.10 14.70

32.

4-Isopropyl Catechol

1

4-Isopropyl

Phenol

1.25 1.25

31

Sr.

No.


y in

MT/

Month

Name of Raw

Materials

Quantity

in T/T

Quantity in

MT/Month

Hydro Bromic

Acid 48%

1.66 1.66

Hydrogen

Peroxide 50%

0.73 0.73

Sodium Thio

Sulphate

0.02 0.02

Caustic Soda

Flakes

0.50 0.50

Cupric Chloride 0.03 0.03

N-Butyl Alcohol 0.25 0.25

HCL 30 % 1.40 1.40

Total 5.84 5.84

33.

1-Adamantyl HCL

8

Adamantane 1.00 8.00

Methylene

Dichloride

1.00 8.00

Catalyst 0.05 4.00


Acetonitrile 2.40 19.20

Methanol 0.50 4.00

Sodium sulphate 0.05 0.40


HCL 30% 0.50 4.00

Total 8.53 68.24

34.

1-Bromo-2-(3-Chloro-

4-Ethoxyphenyl)-2-

Methyl Propane

11

Ortho Chloro

Phenol

0.80 8.80

Zinc dust 0.05 0.55

Sodium

Hydroxide

0.28 3.03

Diethyl sulphate 0.80 8.80

3 Bromo-2-

Methyl-1-

Propane

0.70 7.70

Toluene 0.10 1.10

Methanol 0.10 1.10

Total 2.83 31.08

35.

4-Chloro 2,6 Dimethyl

Phenyl Acetic Acid

8

3-5,xylidene 0.80 6.40

HCL 30% 4.70 37.60

Para 0.30 2.40

32

Sr.

No.


y in

MT/

Month

Name of Raw

Materials

Quantity

in T/T

Quantity in

MT/Month

Formaldehyde

Solution

Sodium Nnitrite 1.00 8.00



Sodium

Hydroxide

0.35 2.80

Total 7.42 59.36

36.

4-Hydroxy Benzyl

Alcohol

3

Para Hydroxy

Benzaldehyde

1.25 3.75

Caustic Soda

Flakes

0.37 1.11

Sodium Boro

Hydride

0.35 1.05

HCL 30% 1.15 3.45

Total 3.12 9.36

37.

2-Methoxy Phenyl

Acetone

1

O-Anialdehyde 1.00 1.00

Methyl-2-

chloropropionate

0.91 0.91

Sodium

Hydroxide 50%

0.40 0.40

Sulpharic Acid 0.15 0.15

Total 2.45 2.45

38.

Methyl-2-Dimethyl

Amino-2-phenyl

butyrare

2

Toluene 0.28 0.56

2-Amino-2-

Phenyl Butyris

Acid

1.12 2.24

Sodium

Hydroxide 50%

1.06 2.11

Dimethyl

Sulphate

0.62 1.24

Formic Acid 0.77 1.54

Formaldehyde

37%

0.70 1.41

Total 4.55 9.10

39.

Meta Phenoxy Benzyl

Alcohol

4

Aluminium

Chloride

0.90 3.60

Bromine 0.85 3.40

33

Sr.

No.


y in

MT/

Month

Name of Raw

Materials

Quantity

in T/T

Quantity in

MT/Month

Benzaldehyde 0.55 2.20

Ethylene

Dichloride

0.10 0.40

Monoethylene

Glycol

0.025 0.10

PTSA 0.003 0.012

Phenol 0.50 2.00

Potassium

Hydroxide

0.30 1.20


Hydrogen 0.01 0.04


Tri ethyl Amine 0.00 0.01

Catalyst 0.01 0.04

Total 3.56 14.24

40.

4-Bromophenyl Acetic

Acid Methyl Ester

1

4-Bromophenyl

Acetic Acid

1.07 1.07

Methanol 0.42 0.42


Soda Ash 0.03 0.03

Total 1.73 1.73

41.

N Methyl 1-

Napthalene Methyl

Amine Hydro Chloride

3

Dimethyl

Formamide

0.08 0.23

Sodium Hydride

60% in Paraffin

0.31 0.92

N-Methyl

Formamide

0.57 1.70

1-Chloro Methyl

Naphthalene

1.13 3.39

Sulphuric Acid

98%

1.13 3.39

Caustic Soda Lye

48%

2.49 7.46

HCL 30% 0.18 0.53

Toluene 0.13 0.39

Total 5.99 17.98

42.

4-Hydroxy

Acetophenone

16

Acetyl Chloride 0.90 14.40

Phenol 1.00 16.00

34

Sr.

No.


y in

MT/

Month

Name of Raw

Materials

Quantity

in T/T

Quantity in

MT/Month

Mono Chloro

benzene

0.30 4.80

Aluminum

Chloride

2.80 44.80

Sodium

Hydroxide

0.20 3.20

HCL 2.00 32.00

Total 7.20 115.20

43.

2-(1-Admantyl)-4-

Bromo Anisole

2

4-Bromo anisole 1.00 2.00

Adamantanol 0.63 1.26


Ethylene

Dichloride

0.50 1.00

Toluene 0.10 0.20

Total 2.68 5.36

44.

2-(3-Hydroxy-2-

Methyl Propionyl)-

aminol-2-methyl-

propanol

10

2-Amino

Isobutyric Acid

0.75 7.50

Methacrylic Acid 0.65 6.50

Toluene 0.10 1.00

HCL 30% 0.50 5.00

Tetrahydrofuran 0.20 2.00

Sodium

Borohydride

0.25 2.50

Caustic Soda

Flakes

0.25 2.50

Total 2.70 27.00

45.

4-Bromophenyl Acetic

Acid

1

4-Bromotoluene 1.16 1.16

AIBN 0.01 0.01

Bromine 1.00 1.00

Sodium Thio

Sulphate

0.02 0.02


Caustic Soda

Flakes

0.25 0.25

HCL 30% 0.76 0.76

Total 3.47 3.47

46. 2-Amino 2-Methyl

Propanol

12

Acetone 1.30 15.60

35

Sr.

No.


y in

MT/

Month

Name of Raw

Materials

Quantity

in T/T

Quantity in

MT/Month


Methanol 0.20 2.40

Ammonium

Carbonate 1.50 18.00

Toluene 0.05 0.60

HCL 30% 2.40 28.80

Sodium

Hydroxide 2.40 28.80

Sodium Boro

Hydrate 0.55 6.60

Total 10.20 122.40

47. 2-Bromo-5-Methoxy-

Benzoic Acid

4

Meta Anisic Acid 0.69 2.76

Ethylene

Dichloride 0.07 0.28

Bromine 0.73 2.90

Total 1.49 5.94

48. 2-Bromo-5-Hydroxy –

Benzoic Acid

4 3-Hydroxy Benzoic

Acid 0.666 2.66

Ethylene

Dichloride 0.050 0.20

Bromine 0.771 3.08

Total 1.487 5.95

49. Diphenylmethane-bis-

4,4’-N,N’-ethylene

Urea (DEU)

8

Monoethanolami

ne 0.540 4.32

HCL 30% 1.200 9.60

Toluene 0.200 1.60


Caustic Flakes 1.500 12.00

4,4'-Diphenyl

methane

Diisocyanate 0.820 6.56

Total 5.490 43.92

50. TrimethylolpropaneTr

is(2-methyl-1-

aziridinepropionate)

8

Isopropanolamin

e 0.680 5.44

36

Sr.

No.


y in

MT/

Month

Name of Raw

Materials

Quantity

in T/T

Quantity in

MT/Month

HCL 30% 1.180 9.44

Toluene 0.100 0.80

Thional Chloride 1.350 10.80


Trimethyl

propane

Triacrylate 0.680 5.44

4-Methoxy

Phenol 0.005 0.04

Total 5.755 46.04

51. PentaerythritolTris([3-

(1-

aziridinyl)propionate]

8 Ethanolamine 0.620 4.96

HCL 30% 1.370 10.96

Toluene 0.090 0.72



Pentaerythritol

Triacrylate 0.750 6.00

4-Methoxy

Phenol 0.005 0.04

Ethanolamine 0.620 4.96

Total 5.945 47.56

52. 2-Bromophenyl

Acetonitrile

1 2-Bromo Benzyl

Bromide 1.430 1.43


tetrabutyl

Ammonium

Bromide 0.030 0.03

Toluene 0.030 0.03

Total 1.760 1.76

53. Phenyl Acetic Acid

Ethyl Ester

8 Phenyl Acetic

Acid 1.000 8.00


Ethanol 0.370 2.96

Sodium

Bicarbonate 0.050 0.40

Total 1.430 11.44

37

Sr.

No.


y in

MT/

Month

Name of Raw

Materials

Quantity

in T/T

Quantity in

MT/Month

54. 3-Methoxy,2-Methyl

Benzoyl Chloride

8 2 Methyl 3

Hydroxy Benzoic

Acid 1.000 8.00

Dimethyl

sulphate 0.620 4.96

HCL 30% 0.100 0.80



Total 3.048 24.38

55. Methyl€-3-methoxy-

2-(2-

chloromethylphenyl)-

2-propenoate

33

Orho Methyl

Phenyl Acetic Acid 1.365 45.05

Mono Chloro

Benzene 0.5 16.50



Methanol 0.15 4.95

Toluene 0.2 6.60

Sodium Hydroxide 0.15 4.95

Sodium Methoxide 0.252 8.32

Methyl Formate 0.3 9.90

Xylene 0.048 1.58

Hydrochloric Acid 0.35 11.55

Dimethyl Sulphate 0.4 13.20

Potassium

Carbonate 0.3 9.90

Orho Methyl

Phenyl Acetic Acid 5.615 185.30

Total 1.365 45.05

56. 2-(2-hydeoxyphenyl)-

3-methoxypropenoic

acid methylester

33

2-Hydroxy phenyl



Methanol 0.235 7.76

Sodium


Sodium

Methoxide 0.65 21.45

38

Sr.

No.


y in

MT/

Month

Name of Raw

Materials

Quantity

in T/T

Quantity in

MT/Month

Methyl Formate 0.36 11.88

HCL 30% 0.15 4.95

potassium


Toluene 0.05 1.65

Xylene 0.05 1.65

Total 3.005 99.17

57. Methyl (2E) -2-( 2-(6-

(2-Cyanophenoxy

)Pyrimidine -4yl)Oxy )

Phenyl Acetate

33 2-Hydroxy Phenyl



Methanol 0.765 25.245

Sodium


4,6 Dichloro

Pyrimidine 0.6 19.8

2-Cyno Phenol 0.2 6.6

Hydrochloric Acid 0.15 4.95

Potassium


Toluene 0.07 2.31

Xylene 0.05 1.65

Total 3.345 110.385

58. 3-CHLORO-4-METHYL

ISOPROPYL BENZOATE

25 Para toluic acid 1.067 26.663

Triphenyl

phosphine 0.001 0.027

Thionyl chloride 1.244 31.093

Chlorine gas 0.594 14.850

Ferric Chloride 0.004 0.090

Isopropyl alcohol 0.715 17.875

Soda asha 0.002 0.060

TOTAL 3.626 90.657

39

CAS No. and LD50 of each Raw Materials

Sr. No. RAW MATERIAL CAS NO. LD 50

1 1,1,2 Tri Chloro ethane 79-00-5 837mg/kg

2 1-Chloro Methyl

Naphthalene 86-52-2 LD50 Rat 890 mg/kg (Oral)

3 2,2 Dimethyl Butanol 75-85-4 2027 mg/kg [sex: M,F]

4 2,4,6-Trimethyl Phenyl

Acetic Acid / Mesitylene 4408-60-0 Lethal Dose-50 %

5

2,4-Dichloro Phenyl Acetic

Acid / 2-4, Dichloro Benzyl

Alcohol 19719-28-9 Oral LD50 Rat: 1410 mg/kg

6 2,5-Dimethyl Phenyl

Acetic Acid 13612-34-5 Lethal dose, 50 percent

7 2,6 Dichloro Toluene 118-69-4 1000 mg/kg/day

8 2,6-Xylenol 576-26-1 LD50 Rat 296 mg/kg

9 2-Amino Isobutyric Acid 62-57-7 Mouse LD50 750 mg/kg

10 2-Amino-2-Phenyl Butyric

Acid 1292413 -

11 2-Aminobenzamide 88-68-6 LD50 Rat 2200 mg/kg

12 2- Bromo Benzyl Bromide 3433-80-5 50 mg/Kg

13 2-Hydroxy Phenyl Acetic

Acid 614-75-5 395 mg/kg

14 2-Methyl2-Butanol 75-85-4 2027 mg/kg [sex: M,F]

15 2-Methyl 3 Hydroxy

Benzoic Acid 603-80-5 -

16 2-Cyno Phenol 611-20-1 3150 mg/kg

17 2-Tert-Butyl-5-Methyl

Phenol 88-60-8 1080 mg/kg [sex: M]

18 3 Bromo-2-Methyl-1-

Propane 98244-48-5 -

19 3-Hydroxybenzoic Acid 99-06-9 rat 3700 mg/kg

20 3-5,xylidene 108-69-0 17 mg/l

21 3-Amino Phenol 591-27-5 LD50 Rat 924 mg/kg

22 4-Bromo anisole 104-92-7 LD50 Rat 1907 mg/kg

23 2-Bromo Benzyl Bromide 3433-80-5 50 mg/Kg

24 4-Bromophenyl Acetic

Acid 1878-68-8 mouse LD50 1050 mg/kg

25 4-Bromotoluene 106-38-7 LD50 Rat > 2000 mg/kg

40

26 4-Chloro Benzaldehyde 104-88-1 LD50 Rat 840 mg/kg

27 4-Isopropyl Phenol 99-89-8 184 mg/kg

28 4,4’-diphenylmethane Di

isocyanate 101-68-8 LD50 Rabbit > 9000 mg/kg

29 4- Methoxy Phenol 149-76-5 LD50 Rat 1600 mg/kg

30 4-6 Dichloro Pyrimidine 1193-21-1 --------

31 Acetic Acid 64-19-7 3310 mg/kg [Rat].

32 Acetic Anhydride 108-24-7 (rat): 1,780 mg/kg

33 Acetone 67-64-1 Dermal, guinea pig: LD50 = >9400 uL/kg

34 Acetonitrile 75-05-8 2460 mg/kg [Rat.]

35 Acetyl Chloride 75-36-5 rat LD50: 910 mg/kg

36 Adamantane 281-23-2 rat: LD50:>10gm/kg.

37 Adamantanol 768-95-6 mouse - 600 mg/kg.

38 AIBN-

Azobisisobutyronitrile 78-67-1 Rat. 100 mg/kg

39 Aluminium Chloride 7446-70-0 Oral, mouse: LD50 = 1130 mg/kg

40 Ammonium Bicarbonate 1066-33-7 Mouse is 245 mg/kg

41 Ammonium Carbonate 506-87-6 mouse - 96 mg/kg

42 Anisole 100-66-3 rat - 3,700 mg/kg

43 Benzaldehyde 100-52-7 rat: LD50 = 1300 mg/kg

44 Benzofuran-3-one-

2(Carboxylate) - -

45 Benzoyl Chloride 98-88-4 Dermal, rabbit: LD50 = 790 mg/kg

46 Benzyl Chloride 100-44-7 Rat 440 mg/kg

47 Bromine 7726-95-6 3100 mg/kg [Mouse]

48 Carbon 7440-44-0 oral rat : >10000 mg/kg

49 Catalyst - -

50 Caustic Soda Flakes 1310-73-2 2000 mg/kg (rat)

51 Caustic Soda Lye 48% 1310-73-2 -

52 Chlorine Gas 7782-50-5

(Daphnia magna/water flea) = 0.097

mg/L

53 Choral 75-87-6 725 mg/kg in rats

54 Copper Chloride 7447-39-4 mouse: LD50 = 233 mg/kg

55 Copper Sulphate 7758-98-7 Rabbit Oral 125 mg/kg

56 Cupric Chloride 7447-39-4 mouse: LD50 = 233 mg/kg

57 Cyanuric Chloride 108-77-0

Rabbit (Russian white, male & female)

dermal >2000 mg/kg

41

58 D V Ester 61898-95-1 -

59 Diethyl sulphate 64-67-5 Rabbit 944 mg/kg

60 Diethylene Glycol 11-46-6 rabbit, LD50. 12,510 mg/kg.

61 Dimethyl Formamide 68-12-2 mouse: LD50 = 2900 mg/kg

62 Dimethyl Sulfoxide 67-68-5 LD50 (rat): 14,500 mg/kg

63 Dimethyl Sulphate 77-78-1 (acute, oral) is 205 mg/kg (rat)

64 Ethanol 64-17-5 mouse: LD50 = 3450 mg/kg;.

65 Ethyl Chloro Acetate 105-39-5 rat: LD50. = 180 mg/kg;

66 Ethylene Dichloride 107-06-2 mouse: LD50 = 413 mg/kg

67 Ethylene Dichloride 107-06-2 mouse: LD50 = 413 mg/kg

68 Ethylene Glycol 107-21-1 mouse: LD50 = 5500 mg/kg

69 Ethanolamine 141-43-5 LD50 = 700 mg/kg; Oral, rabbit

70 Formaldehyde 37% 50-00-00 rat. 500 mg/kg.

71 Formic Acid 64-18-6 LD50 Oral - Rat - 730 mg/kg

72 HCL 30% 7647-01-0 LC50, 24 h : 20,5 mg/l

73 HexamethyleneTetramine 100-97-0 LD50 Rat 9200 mg/kg

74 Hydrazine Hydrate 80% 7803-57-8 [Rat]. 4960 mg/kg

75 Hydro Bromic Acid 48% 10035-10-6

LD50 (inhalation,rat): HBr 100% 2,858

ppm/1h

76 Hydrogen 1333-74-0 LD50 (Oral-Mouse) 1250 mg/kg

77 Hydrogen Peroxide ( 50%) 7722-84-1 LD50): 4000 mg/kg (Mouse)

78 Isopropanolamone 78-96-6 Rat. LD50. 2700 mg/kg

79 Iso Propyl Alcohol 67-63-0 LD50 = 3600 mg/kg;. Oral, mouse

80 Monoethanolamine 141-43-5 LD50 (Oral, Rat) = 1720 MG/KG

81 Mesitylene 108-67-8 ORL RAT LD50 1400 mg/kg

82 Meta Xylenol / 3-5 Xylenol 108-68-9 mouse LD50 156 mg/kg

83 Meta Anisic Acid 586-38-9 (LD50): Acute: 5000 mg/kg [Rat].

84 Methacrylic Acid 79-41-4 Rabbit LD50. (dermal) 500 mg/kg.

85 Methanol 67-56-1 ORL MUS LD50 7300 mg/kg

86 Methyl 2(2-Ethoxy-2-

Oxoethoxy)Benzoate 22511-42-8 -

87 Methyl Formate 107-31-3 LD50 = 17100 mg/kg ( Rabbit ).

87 Methyl Salicylate 119-36-8 mouse: LD50 = 1110 mg/kg

89 Methyl-2-

chloropropionate 17639-93-9 -

90 Methylene Dichloride 75-09-2 ORAL (LD50): Acute: 1600 mg/kg

42

91 Mono Chloro benzene 68411-45-0 400 to 1600 mg/kg

92 Monoethylene Glycol 107-21-1 Oral LD50 (rat): 4700 mg/kg

93 N-Butyl Alcohol 71-36-3 LD50 Rat 790 mg/kg

94 Nitrobenzene 98-95-3 LD50 2100 mg/kg body weight.

95 N-Methyl Formamide 123-39-7 Rat LD50 (oral) 4000mg/kg

96 N-Methyl-2-Pyrolidinine 872-50-4 LD 50 oral, LD50 Rat 3598 mg/kg

97 O-Anialdehyde 135-02-4 LD50 [sex: M,F] 1260 mg/kg

98 Ortho Chloro Benzyl

Cyanide 2856-63-5 Oral (rat) LD50: 430 mg/kg

99 Ortho Chloro Phenol 95-57-8 LD50 Rat 670 mg/kg

100 Ortho Dichloro Benzene 95-50-1 LD50 Dermal - Rabbit - > 10.000 mg/kg

101 Ortho Methyl Phenyl

Acetic Acid 644-36-0 Oral LD50 (rat): 2250 mg/kg

102 Para Chloro Phenol 106-48-9

oral-mammal (species unspecified) LD50

500 mg/kg

103 Para Chloro Benzoic Acid 74-11-3 Rat LD50 (oral) 1170 mg/kg

104 Para Cresol 106-44-5 LD50 Rat 207 mg/kg

105 Para Formaldehyde 30525-89-4 ORAL (LD50): Acute: 800 mg/kg [Rat].

106 Para Hydroxy

Benzaldehyde 123-08-0 mouse: LD50 = 2720 mg/kg

107 Para toluic acid 99-94-5 LD50 Oral - mouse - 2,340 mg/kg.

108 Per Chloro Ethylene 127-18-4 LD50. 2629 mg/kg.

109 Pentaerythriotol Tri

Acrylate 3524-68-3 -

110 Phenol 108-95-2 LD50 Dermal - Rabbit - 630.0 mg/kg

111 Phenyl Acetic Acid 103-82-2 Oral LD50 (rat): 2250 mg/kg

112 PhosphorousPenta

chloride 10026-13-8 LD50 Rat 660 mg/kg

113 Pivaloyl Chloride 3282-30-2 Rabbit > 2010 mg/kg

114 Poly Phosphoric Acid 8017-16-1 LD50 = 50 to 500 mg/kg

115 Potassium Carbonate 584-08-7 mouse: LD50 = 2570 mg/kg

116 Potassium Hydroxide 1310-58-3 Oral LD50 (rat): 273 mg/kg

117 Potassium Iodide 7681-11-0 LD50 > 3000 mg/kg (oral/rat).

118 PTSA( p-Toluenesulfonic

acid ) 104-15-4 LD50 = 1410 mg/kg ( Rat )

119 Soda Ash 497-19-8 LC50. 2.30 mg/l

120 Sodamide 7782-92-5 -

121 Sodium Bi Carbonate 144-55-8 Rat LD50: =4220 mg/kg

43

122 Sodium Boro Hydride 16940-66-2 (LD50): 50 mg/kg [Rabbit].

123 Sodium Cyanide 144-33-9 6.44 mg/kg [Rat].

124 Sodium Hydride 60% in

Paraffin 7646-69-7 -

125 Sodium Hydroxide 1310-73-2 mouse: LD50 = 6600 mg/kg

126 Sodium Hydroxide 50% 1310-73-2 LD50 Rat 140-340 mg/kg

127 Sodium Hydroxide

Solution 7732-18-5 -

128 Sodium Hypochloride 7681-52-9 Oral (mouse) LD50: 5800 mg/kg

129 Sodium Metal 7440-23-5 58000 mg/kg mouse

130 Sodium Methoxide 124-41-4 rat: LD50 => 2000 mg/kg

131 Sodium Nnitrite 7632-00-0 mouse - 158 mg/kg.

132 Sodium Sulphate 7757-82-6 LD50(orl,mouse): 5989mg/kg

133 Sodium Thio Sulphate 7772-98-7 rat LD50: >2500 mg/kg

134 Succinic Anhydride 108-30-5 ORAL (LD50): Acute: 1510 mg/kg .

135 Sulphuric Acid 7664-93-9 Rat, Oral, 2140mg/kg

136 Sulphuryl Chloride 7791-25-5 LD50 for rats is 130 mg/kg.

137

Tetra Butyl Ammonium

Bromide / TBAB ( Cat.

) 1643-19-2 oral. LD50. 2143,38 mg/kg rat.

138 Ter. Butanol 75-65-0 3559 mg/kg

139 Tetra Ethyl Benzyl

Ammonium Chloride 56-37-1 338 mg/kg [Mouse].

140 Tetrahydro Furan 109-99-9 rat - 2,050 - 2,850 mg/kg

141 Tetrahydrofuran 109-99-9 rat - 2,050 - 2,850 mg/kg

142 Thionyl Chloride 7719-09-7 Oral - rat - 324 mg/kg

143 Titanium Tetrachloride 7550-45-0 > 10 g/kg inh rat

144 Toluene 108-88-3 > 5000 mg/kg ( Rat )

145 Tri ethyl Amine 121-44-8 mouse: LD50 = 546 mg/kg

146 Tri Methyl Propane Tri

Acrylate - -

147 Tri phenyl phosphine 603-35-0 mouse LD50: 1380 mg kg.

148 Vinylidene Chloride 75-35-4 200 mg/kg oral-rat

149 Xylene 1330-20-7 [oral, rat]; 4300 mg/kg

150 Zinc dust 74406-66-6 7950 mg/kg [Mouse]

44

Annexure – II

Layout of the Plant

45

Annexure –III

Manufacturing Process

1. 2-Amino Benzo Nitrile

Process Description:

2-Amino-benzamide is dehydrated with phosphorus pentachloride. After reaction completion,

reaction mixture was quenched in water and pH was adjusted up to 6.5-8.5 Separate the

organic layer, Product was distilled off under reduce pressure after distillation of solvent.

Chemical Reaction:

Mass Balance:

46

2. 2-Amino-5-Bromo Benzo Nitrile


2-Amino-benzonitrile is brominated with N-bromosuccinimide in presence of solvent DMF.

After reaction completion,DMF is recovered, added water and filter the crude product. Crude

product was crystallized with toluene to get the pure material.

Chemical Reaction:

47

Mass Balance:

48

3. 2,4,6-Trimethyl Benzaldehyde (Mesitaladehyde)


Chloral and mesitylene are reacted in presence of Titanium chloride.Product obtained is

isolated after quenching ,mass is hydrolyzed with soda ash to make product mesiatldehyde.

Distilled mesitsldehyde is mixed with acetone to get 84 % concentration.

Chemical Reaction:

49

Mass Balance:

50

4. Indoline


2-Chlororphenethyl amine is reacted with aq. ammonia in autoclave with presence of Copper

chloride to produce indoline. After washing this crude mass is distilled under reduced pressure

to get pure Indoline.

Chemical Reaction:

Mass Balance:

51

5. 2,4-Dichloro Phenyl Acetic Acid


2,4-Dichlorobenzyl chloride is reacted with Sodium cyanide to make 2,4-Dichlorobenzyl

cyanide.

2,4-Dichlorobenzyl cyanide is then hydrolyzed with caustic soda to make 2,4-

Dichlorophenylacetic acid

Chemical Reaction:

52

Mass Balance:

53

6. 2,4-Dichloro Phenyl Acetyl Chloride


2,4-Dichlorophenyl acetic acid is chlorinated with Thionyl chloride, using toluene as solvent to

convert it to 2,4-Dichlorophenyl acetyl chloride. The product is isolated after recovery of

toluene by doing high vacuum distillation and pure product is collected separately.

Chemical Reaction:

Mass Balance:

54

7. 2,4,6-Trimethyl Phenyl Acetyl Chloride


2,4,6-Trimethylphenyl acetic acid is chlorinated with thionyl chloride to convert it to 2,4,6-

Trimethylphenyl acetyl chloride using Toluene as solvent.

Chemical Reaction:

Mass Balance:

55

8. 2,4-Dichloro Meta Cresol


2-tertiary Butyl -5-Methyl is chlorinated with Sulphuryl chloride and Dichloro compound is

dealkylated using aluminium chloride and distilled to get the 2,4 di Chloro meta cresol.

Chemical Reaction:

56

Mass Balance:

57

9. Pivolonitrile (Trimethylacetonitrile)


Pivalamide is dehydrated using Phosphorus pent oxide to make Pivalonitrile

Chemical Reaction:

Mass Balance:

58

10.4,4-Dihydroxy Benzophenone


4-Chloro, 4’-hydroxy benzophenone is hydrolyzed with caustic solution under pressure in

autoclave to make 4, 4’-Dihydroxy benzophenone.

Chemical Reaction:

59

Mass Balance:

60

11. 2-Chloro-4,6 Dimethoxy-1,3,5-Triazine


Cyanuric chloride is reacted with methanol in presence of Sodium bicarbonate to make 2-

Chloro-4,6-dimethoxy-1,3,5-Triazine.After reaction mass is washed and organic mass distilled

under vacuum and flakes are made.

Chemical Reaction:

Mass Balance:

61

12. 2-Coumaranone 30%,Acetic Anhydride70 %


Ortho chloro benzyl cyanide ( OCCN ) is converted to Ortho hydroxyl phenyl acetic acid sodium

salt in Autoclave.Autoclave mass is acidified with HCl to make Ortho hydroxyl phenyl acetic acid

(OHPAA).This OHPAA is then cyclised removing water azotropically using toluene to make 2-

Couraranone (2-C).

2-Coumaranone is blended with acetic anhydride to make 30 % 2-Coumaranonein Acetic

anhydride solution.

Chemical Reaction:

62

Mass Balance:

63

13. 4-Bromo-2-Hydroxy Anisole / 5-Bromo-2-Methoxy Phenol


2-methoxy phenol is acetylated with acetyl chloride and then brominated with bromine to

form protected 5-bromo-2-methoxy phenol . The brominated compound is hydrolysed with

sodium hydroxide to obtain crude product. Crude product was crystallized with toluene and

hexane mixture.

Chemical Reaction:

64

Mass Balance:

65

14. 5-Propionyl-2-Thiophenyl Phenyl Acetic Acid (PPP) / OR

2-Phenyl Thio-5-Propionyl Phenyl Acetic Acid


2-Phenylthio-5-propionyl phenyl acetic acid (PPP) interacts with bromine, Trimethyl

Orthoformate (TMOF) in presence of Zn to produce Diester ,then Diester hydrolise with help

sodium hydroxide flakes then acidified with acid to produce Diacid.

Chemical Reaction:

66

Mass Balance:

67

15. 2,3,4,5-Tertrachloro Benzoyl Chloride


2,3,4,5-Tetrachloro phthalic anhydride is hydrolyzed with caustic flakes to 3,4,5,6- Tetrachloro

phthalic acid which is decarboxylate to make 2,3,4,5-Tetrachloro benzoic acid .This benzoic acid

is then reacted with thionyl chloride to make 2,3,4,5-Tetrachloro benzoyl chloride (TCBOC)

Chemical Reaction:

68

Mass Balance:

69

16. 3,4,5 Trimethoxy Toluene


Para cresol is brominated with Hydro bromic acid with help of Hydrgen peroxide to produce

2,6-Dibromo para cresol. Then this dibromo para cresol is converted in to 2,4,6-Trimethoxy

toluene by using sodium methoxide and methanol. After washing material is distilled to get

pure 3,4,5-Trimethoxy toluene

Chemical Rection:

70

Mass Balance:

71

17. 3,4,5 Trimethoxy Benzyl Chloride


3,4,5 Trimethoxy benzyl alcohol is reacted with HCl to produce pure 3,4,5 Trimethoxy benzyl

chloride..

Chemical Reaction:

Mass Balance:

72

18. 3,4,5-Trimethoxy Benzyl Cyanide


3,4,5 Trimethoxy Benzyl chloride is interacted with sodium cyanide solution along with phase

transfer catalyst to produce 3,4,5 Trimethoxy Benzyl Cyanide after distillation.

Chemical Reaction:

Mass Balance:

73

19. 3,4,5-Trimethoxy Phenyl Acetic Acid


3,4,5 Trimethoxy Benzyl Cyanide is reacted with caustic solution to produce sodium salt of 3,4,5

Trimethoxy Phenyl Acetic Acid after isolation with dil. Hydrochloric acid to produce pure 3,4,5

Trimethoxy Phenyl Acetic Acid.

Chemical Reaction:

Mass Balance:

74

20. 3,4,5-Trimethoxy Benzoic Acid


Para cresol is brominated with Hydro bromic acid with help of Hydrgen peroxide to produce

2,6-Dibromo para cresol.Then this dibromo para cresol is converted in to 2,4,6-Trimethoxy

toluene by using sodium methoxide and methanol.After washing material is distilled to get pure

3,4,5-Trimethoxy toluene. Then this trimethoxy toluene is converted in to 3,4,5 Trimethoxy

Benzoic Acid by air oxidation in Autoclave.

Chemical Reaction:

75

Mass Balance:

76

21. 3,4,5-Trimethoxy Benzaldehyde


3,4,5 Trimethoxy Toluene is selectively oxidized with MnO2 in presence of H2SO4 to produce

pure 3,4,5-Trimethoxy Benzaldehyde after fractional distillation.

Chemical Reaction:

Mass Balance:

77

22.4,4-Dimethoxy-2-Butanone

Process Description

Acetone and methylformate and sodium methoxide are reacted in presence of toluene to make

sodium methyl formate (Sodium formyl acetone,SFA).Sodium formyl acetone is then reacted

with methanol and Sulfuric acid to make 4,4-Dimethoxy-2-Butanone (DMB)

Chemical Reaction:

78

Mass Balance:

79

23. R-2-(2,4-Dichlorophenoxy) Propionic Acid


2,4-dichlorophenol is condensed with sodium-2-chloropropionate in presence of sodium

hydroxide after reaction completion reaction mass was quenched in water. Aq. Layer was

washed with toluene and acidfy with hydrochloric acid to obatin racemic mixture of 2,4-

Dichlorophenoxypropionic acid which was resolved with phenylethylamine to get pure (R)-2-

(2,4-Dichlorophenoxy)propanoic acid.

Chemical Reaction:

80

Mass Balance:

81

24. Para Methyl Benzaldehyde / 4-Methyl Benzaldehyde


P-Xylene is chlorinated with chlorine gas by using catalyst Triphenyl Phosphine oxide (TPPO),

After chlorination recover unreacted P-xylene by using fractional distillation & remaining PMBC

with hexamine and Hydrochloriac acid & water produce 4-Methyl Benzaldehyde The pure 4-

Methyl Benzaldehyde is produced by fractional distillation.

Chemical Reaction:

82

Mass Balance:

83

25. 2-5 Dimethyl Phenyl Acetyl Chloride


2,5-Dimethylphenyl acetic acid is chlorinated with thionyl chloride to convert it to 2,5-

Dimethylphenyl acetyl chloride using Toluene as solvent.

Chemical Reaction:

Mass Balance:

84

26. 2-Amino- 2-Phenyl Butyric Acid


Propiophenone is converted to 2-Amino-2-phenyl butanenitrile by reacting with sodium

cyanide and Ammonium chloride using methanol as solvent. The2-amino-2-phenylbutanenitrile

is then hydrolyzed in e with caustic to make 2-Amino-2-Phenyl butyric acid.

Chemical Reaction:

85

Mass Balance:

86

27. 1-(2,6 Dichloro Phenyl)-2-Indolinone


Step 1 : Manufacture of 2,6 Dichloro Diphenyl Amine ( DCDPA)

2,6 Dichloro phenol is reacted with alkyl chloro acetate in presence of K2CO3 and toluene in a

clean SS 316 reactor at reflux temperature to get 2,6 Dichlrophenoxy alkyl acetate ( Ether). This

ether is further reacted with Aniline using sodium Methoxide to get 2,6 Dichloro Diphenyl

Amine ( DCDPA.)

Step 2 : Manufacture of N-Chloro acetyl-N-phenyl-2,6- dichloroanilene ( CAD )

In a clean glass line reactor, charge & 2,6 Dichloro Diphenyl Amine and react with chloro acetyl

chloride. Add methanol and chill to 15-20°c. Filter it & dry at 80-90° till LOD-0.1%. The sample

is test for purity and takes for further reaction.

Step 3 : Manufacture of 1-(2,6-Dichlorophenyl)-2-Indolinone ( Indolinone)

In a clean glass line reactor, charge DC-2 & Aluminium chloride. Heat the mass & convert to

Indolinone after cylisation..

Step 4 : Purification of 1-(2,6-Dichlorophenyl)-2-Indolinone

This crude Indolinone purified in toluene to get pure Indolinone.

Chemical Reaction:

87

Mass Balance:

91

28. 2-(3-Benzoyl phenyl)-Propio nitrile / Ketoprofen Nitrile


Step-1:

3-methylbenzophenone reacted with bromine using MCB as solvent and catalyst AIBN. The

crude product was crystallised using methanol as solvent to obtain 3-

bromomethylbenzophenone .

Step-2:

3-bromomethylbenzophenone is reacted with sodium cyanide using IPA as a solvent. The

product is isolated after solvent recovery followed by high vacuum distillation.

Step-3:

3-(Cyanomethyl) benzophenone is methylated with dimethyl carbonate using potassium

carbonate as base. Product was extracted in toluene and re-crystalized in haxane to obtain pure

ketoprofen nitrile.

Chemical Reaction:

92

Mass Balance:

93

29. N-Methyl-1-Naphtahlene Methyl Amine Acetate


1-Chloromethyl naphthalene is reacted with n-Methyl formamide in presence of Sodium

hydride and Dimethyl formamide to make N-(Methyl-formyl) methyl naphthalene. This N-

(Methyl-formyl) methyl naphthalene is then hydrolyzed with sulphuric acid and neutralized

with caustic solution to get N-Methyl -1-Naphtahlene Methyl Amine base which is distilled

under partial vacuum. Base is reacted with Acetic acid in presence of toluene to make Acetate

salt.

Chemical Reaction:

94

Mass Balance:

95

30. N-Methyl-1-Naphtahlene Methyl Amine Base





with caustic solution to get N-Methyl -1-Naphtahlene Methyl Amine base.

Chemical Reaction:

96

Mass Balance:

97

31. Para Chloro Phenyl Ethyl Amine / 2-(4-Chloro-Phenyl)-Ethylamine


Para Chloro Benzyl Cyanide in presence of Raney nickel in Methanol. After reaction

completion, diatilled out Methnaol . After recovery of solvent product was distilled out under

reduced pressure.

Chemical Reaction:

Mass Balance:

98

32. Ortho Chloro Phenyl Ethyl Amine / 2-Chloro Phenethyl Amine


2-Chloro benzyl cyanide is reacted under pressure with hydrogen in autoclave in presence of

Raney nickel catalyst to produce 2-Chlororphenethyl amine.

Chemical Reaction:

Mass Balance:

99

33. 2-Dimethylamino-2Phenyl Butanol / 2-(N,N-Dimethyl amino)-2-Phenyl-1-Butanol


2-Amino-2-Phenylbutyric acid is converted to its methyl ester, Methyl-2-amino-2-

phenylbutyrate with dimethyl sulphate using toluene as solvent. Methyl-2-amino-2-

phenylbutyrate is then converted to Methyl-2-(N, N-dimethylamino)-2-phenylbutyrate by

reacting with Formic acid and Formaldehyde.

Methyl-2-(N, N-dimethyl amino)-2-phenylbutyrate is reduced with Sinhydrid / Vitride [ sodium

dihydrobis(2-ethoxymethoxy)-aluminum Hydride] to make 2-Dimethylamino-2-phenylbutanol.

Chemical Reaction:

100

Mass Balance:

101

34. Methyl- 2- Dimethylamino-2- Phenyl butyrate / 2-(N,N-Dimethyl amino)-2-Phenyl-2-

Butyrate


2-Amino-2-Phenylbutyric acid is converted to its methyl ester, Methyl-2-amino-2-

phenylbutyrate with dimethyl sulphate using toluene as solvent. Methyl-2-amino-2-

phenylbutyrate is then converted to Methyl-2-dimethylamino-2-phenylbutyrate by reacting

with Formic acid and Formaldehyde solution. The pure product is obtained after fractional

distillation.

Chemical Reaction:

102

Mass Balance:

103

35. 2-Phenyl Butyric Acid


Benzyl cyanide is reacted with Ethyl Bromide in alkaline condition and the nitrile intermediate is

hydrolysed in acidic condition and then distilled to get the pure product.

Chemical Reaction:

104

Mass Balance:

105

36. 5-Chloro-2-Hydroxy Benzo phenone


Freidel craft reaction of Para chloro phenol (PCP) and Benzoyl chloride (BOC) with Aluminum

chloride is carried out in presence Ortho dichloro benzene (ODCB) as solvent to make product

5-Chloro-2-Hydroxy benzophenone (5-Cl-2-H-BP).

Chemical Reaction:

Mass Balance:

106

37. 5-(1- Carboxy Ethyl)-2-(Phenylthio)phenyl Acetic Acid (DIACID)


2-Phenylthio-5-propionyl phenyl acetic acid (PPP) interacts with bromine, Trimethyl

Orthoformate (TMOF) in presence of Zn to produce Diester ,then Diester hydrolise with help

sodium hydroxide flakes then acidified with acid to produce Diacid.

Chemical Reaction:

107

Mass Balance:

108

38. N-Methyl 1-Napthalene Methyl Amine Hydrochloride






under partial vacuum. Base is reacted with HCl gas in presence of toluene to make Hydro

chloride salt.

Chemical Reaction:

109

Mass Balance:

110

39. 7-Methoxy 1 Tetralone


The condensation of anisole with succinic anhydride give β-(4-methoxybenzoyl)-propionic acid

The reduction of the same with hydrazine hydrate in presence of Potassium hydroxide give 4-

Methoxy pheny Butyric acid which further cyclised to 7-Methoxy 1-tetralone.

Chemical Reaction:

111

Mass Balance:

112

40. 2-Amino 4 Hydroxy Acetophenone

Manufacturing Process:

3-Aminophenol’s, hydroxy and amino groups are protected with acetyl group by reacting with

acetyl chloride in presence of Soda ash. Thus 3-Acetamidophenylacetate forms is heated in

presence of aluminum chloride for fries rearrangement to make N-(2-Acetyl-5-Hydroxyphenyl)

acetamide.

This then converted to 2-Amino-4-Hydroxyacetophenone by reacting with Sodium methoxide

in toluene.

The final product is fractionated under high vacuum to get 2-Amino-4-Hydroxyacetophenone.

Chemical Reaction:

OH NH2

+ 2-CH3COCl

NHCOCH3CH3COONHCOCH3OH

COCH3

NHCOCH3CH3COO

NHCOCH3OH

COCH3

NH2OH

COCH3

3-Amino phenol Acetyl chloride 3-acetamidophenyl acetate

N-(2-acetyl-5-hydroxyphenyl)acetamide

N-(2-acetyl-5-hydroxyphenyl)acetamide 2-Amino-4-Hydroxyacetophenone

Fries rearragement

NaOMe

Nitrobenzene

Soda ash

3-acetamidophenyl acetate

MW:109.12 MW:78.49 MW:193.19

MW:193.19 MW:193.19

MW:193.19 MW:151.16

AlCl3

Toluene

Step 01: Preparation of 3-Acetamidopheyl acetate

Step 02: Preparation of N-(2-Acetyl-5-hydroxyphenyl) acetamide

Step 03: Preparation of 2-Amino-4-Hydroxyacetophenone

+ 2 NaCl 2 CO2+

113

Flow Diagram:

114

41. 3-coumaranone

Process Description:-

In first step Ethylchloro Acetate is added to Methyl Salicylate, Dimethyl formamide and

Potassium Carbonate after reaction Potassium Chloride salt is filtered then after Dimethyl

Formamide recovery product Methyl 2 (2-Ethoxy-2-Oxoethoxy) Benzoate is obtained. In second

step Carboxylation of Methyl 2 (2-Ethoxy-2-Oxoethoxy) Benzoate the product Benzofuran-3-

One-2 (Carboxylate) is obtained and Hydrolysis of this product gives 3-Coumaranone

Chemical Reaction:- STEP I

COOCH3

OH

+Cl

O

OC2H5

COOCH3

O

O

OC2H5

K2CO3/Tolune

Catalyst

STEP II

COOCH3

O

O

OC2H5

CH3ONa/Toluene

HCl

O

O

COOCH3

O

O

COOCH3

STEP III

KOH/Methanol

O

O

Methyl Salicylate M.W.=152 Ethyl Chloroacetate M.W.=122

Methyl 2 (2-Ethoxy-2-Oxoethoxy) Benzoate

3-Coumaranone M.W.=134

Methyl 2 (2-Ethoxy-2-Oxoethoxy) Benzoate Benzofuran-3-One-2 (Carboxylate) M.W.=192

Benzofuran-3-One-2 (Carboxylate) M.W.=192

115

Mass Balance:

116

42. 3, 3 Dimethyl Butyrl Chloride


This is three step process. In first step hydrolysis of 1,1,2-Trichloroethane by using sodium

hydroxide solution in presence of carbon at low temperature to form Vinylidene Chloride

during reaction Vinylidene Chloride is collected in receiver. In second step condensation is

carried out by using (Vinylidene Chloride + Ter. Butanol) mixture is added to H2SO4 at low

temperature. After quenching crude 3,3- Dimethyl Butyric Acid is formed after distillation pure

material is collected and next reaction takes place in Thionyl Chloride to produce 3, 3- Dimethyl

Butyryl Chloride

Chemical Reaction:-

ROS OF 3 3 DimethylButyryl Chloride

Cl

CH 2 HC

Cl

Cl

+ NaOH C

ClH 2C

Cl

+NaCl

OH + H2C

C l

Cl

H 2SO 4O

O H

O

OHCl

S

O

Cl

Add slowly

O

Cl

(Crude)

DistillO

Cl

(Pure material)

1,1,2-Trichloro ethane M.W.=133 Vinylidene Chloride M.W.=96.94

Tert. Butanol M.W.=88 Vinylidene chloride =96.94 3,3-Dimethyl Butyric acid M.W.=116

3,3-Dimethyl Butyric acid

M.W.=116

Thionyl Chloride

M.W.=119

3,3-Dimethyl Butyryl Chloride M.W= 135

+So2 +HCl

+ 2 HCl

117

Mass Balance:

118

43. 4-bromo Anisole


This is single Step reaction. Anisole is Brominated by using Bromine and Hydrogen Peroxide.

After reaction Crude material of 4-Bromo Anisole is obtained. Crude Material Washing by using

Sodium Hydroxide solution. After distillation pure 4-Bromo Anisole is formed.

Chemical Reaction:-

OCH3

+ HBr + H2O2

Acetic acid/Br2

OCH3

Br

4-Bromo Anisole M.W.=187

Anisole M.W.=108

NaOH + NaBr

Mass Balance:

119

44. 4-Cyano Benzoic Acid


To the stirred solution of 4-chlorobenzoic acid in DMF was added catalytical amount of

potassium iodide and sodium cyanide by lot-wise at 20-25oC. Reaction maintain at 110-

115oC for 12 hr. for completion. Recover the DMF and add water. Filter the product, wash

with plenty of water, followed by slurry wash with cyclohexane. Recover the cyclohexane

from the filtrate, to get back the un-reacted 4-chlorobenzoic acid and the residue is dry in

oven to afford pure 4-Cyanobenzoic acid.

Chemical Reaction:

HOOC

Cl

HOOC

CN

NaCNKI

DMF

C8H5NO2Mol. Wt.: 147.13

4-Chlorobenzoic acid 4-Cyano-benzoic acidC7H5ClO2

Mol. Wt.: 156.57

+ NaCl + KI + DMF (R)

Sodium chloride Potassium iodide

ClNaMol. Wt.: 58.44

IKMol. Wt.: 166.00

Mass Balance:

120

OCH 3

+ O

O

O

+ Al2O 3 + HCl

Anisole Succinic anhydride 4-(4-Methoxyphenyl)-4-Oxobuty ric ac id Alum inium ox ide

MW :108.14 MW :100.07 MW :208.21 MW :101.96

OCH 3

O

O H

O4-(4-Methoxyphenyl)-4-Oxobutyric ac id

MW : 208. 21

+

4-(4-Methoxyphenyl)-butyric ac id

MW : 194.23

+ N2NH 2NH 2

KOH , DEG

4-(4-Methoxypheny l)-butyri c ac id

MW :194 .23

+

Poly phosphoric ac id

PPA

OCH 3

O

7-Methoxy-1-tet ralone

MW :176.21

+ H 3PO 4

OCH 3

O

7-Methoxy-1-tet ralone

MW :176.21

OH

O

7-H ydroxy-1-tetra lone

MW :176.21

+ +CH 3OH Al2O 3

AlCl3

Toluene

Methanol Aluminium oxide

MW :101.96MW :32.04

OCH 3

O

O H

OCH 3

O

O H

Ste p: 01 Prepara tion of 4-(4-Methoxyphenyl)-4-ox oburtyric acid

Ste p: 02 Prepara tion of 4-(4-Methoxyphenyl)-burtyric acid

Ste p: 03 Prepara tion of 7-Methox y-1-te tra lone

Step: 04 Prepara tion of 7-Hydrox y-1-te tra lone

OCH 3

O

O H

O

EDC+AlCl 3 33

45. 7-Hydroxy 1 Tetralone

Process description:

Anisole is reacted with Succinic anhydride in presence of Aluminum chloride to make 4-(4-

Methoxyphenyl)-4-oxobutyric acid (MPOB).After washing/ isolation, this is reacted with

Hydrazine hydrate 80% in presence of Potassium hydroxide to reduce to 4-(4-Methoxyphenyl)-

butyric acid (MPPB). 4-(4-Methoxyphenyl)-butyric acid is then cyclalized to 7-Methoxy -1-

tetralon by using Poly phosphoric acid. After isolation /washing this 7-Methoxy -1-tetralon is

demethylated in presence of Aluminum chloride to make 7-Hydroxy -1-tetralon.

Chemical Reaction:

121

Mass Balance:

123

46. Atropic acid

BRIEF MANUFACTURING PROCESS

To the stirred solution of phenyl aceticacid in toluene was added potassium carbonate, para

formaldehyde and catalytical amount of tetrabutylammonium bromide at 20-25oC. Reaction

maintain at 105-110oC for 12 hr. After completion, quench with water, acidify with HCl to pH

1-2 and separate the layers. Organic layer, distil-off the toluene to afford the pure atropic

acid / 2-phenylpropenoic acid.

REACTION SCHEME:

OH

O

Atropic acid

C9H8O2

Mol. Wt.: 148.16

MP: 105-109oC

para HCHOK2CO3 / TBAB

TolueneHCl (30%)OH

O

Phenyl aceticacid

C8H8O2

Mol. Wt.: 136.15

MP: 76-78oC

+ 2 KCl 2 H2O CO2TBAB (cat.)+ ++ (g)

Mass Balance:

124

47. 4-chloro Benzaldehyde Glycol Acetal


4-Chlorobenzaldehdye is reacted with ethylene glycol in presence of p-toluesulphonic acid and

toluene.Thus water formed is collected azotropically. After completion of reaction toluene is

recovered and rest is fractionated to get pure product.

Chemical Reaction:

Cl

Cl

CHO

+OH

OH

Toluene

PTSA

p-Chloro benzaldehyde Ethylene Glycol 2-(4-Chlorophenyl)-1,3-Dioxolane

MW:140.56 MW: 62.06 MW:176.64

Mass balance:

125

48. 2,2-Dichloro-2 Phenyl Acetic Acid Ethyl Ester


This is three step reaction. In first step Thionylation of Phenyl Acetic Acid form Phenyl Acetyl

Chloride obtained. In the second step phenyl Acetyl Chloride is chlorinated to form Alpha Alpha

- Dichloro Phenyl Acetic Acid in presence of catalyst then esterification of Alpha Alpha - Dichloro

Phenyl Acetic Acid to form Alpha Alpha Dichloro Phenyl Acetic Acid Ethyl Ester (DCPAC).

Chemical Reaction:

CH2COOH

+ Socl2

CH2COCl

+ SO2+ HCl

CH2COCl

+ Cl2

O

Cl

ClC

Cl

+ 2HCl

O

Cl

ClC

Cl

+ C2H5

---OH

O

C2H5

ClC

Cl

+HCl

Phenyl acetic acid M.W.=136

P.Acetyl Chloride M.W.=147

P.Acetyl Chloride M.W.=147 Alpha alpha dichloro phenyl acetyl chloride M.W =223

Alpha alpha dichloro phenyl acetyl chloride M.W =223 Alpha alpha dichloro phenyl ethyl ester M.W =217

126

Mass Balance:

127

49. Para Chloro Meta Xylenol BP


Meta Xylenol is chlorinated with Chlorine in presence of Cupric chloride and Hydrochloric acid

(HCl) to make Para Chloro Meta Xylenol (PCMX).Reaction mass is filtered to get brown coloured

PCMX and Mother liquor is recycled after top up fresh meta xylenol , HCl 30 % and cupric

chloride.

Brown coloured PCMX is purified in Per chloro ethylene (PCE) to make BP grade PCMX.

Chemical Reaction:

Mass Balance:

128

50. Pivaloacetonitrile


Para cresol is brominated with Hydro bromic acid with help of Hydrgen peroxide to produce 2,6-

Dibromo para cresol.Then this dibromo para cresol is converted in to 2,4,6-Trimethoxy toluene by using

sodium methoxide and methanol.After washing material is distilled to get pure 3,4,5-Trimethoxy

toluene. Then this trimethoxy toluene is converted in to 3,4,5 Trimethoxy Benzoic Acid by air oxidation

in Autoclave.

Chemical Reaction:

CH3

OH

+ BrH + H2O2

+ NaOCH3 + CH3OH

Para Cresol 2,6-Dibromo-Para Cresol

3,4,5-Trimethoxy toluene

MW: 108.13 MW: 265.93

MW: 182.22

Sod.Methoxide

CuCl2

BrBr

CH3

OH

BrH

OCH3

CH3

OCH3

H3CO

+

3,4,5-Trimethoxy toluene

MW: 182.22

OCH3

CH3

OCH3

H3CO

Air oxidation

3,4,5-Trimethoxy Benzoic Acid

OCH3

COOH

OCH3

H3CO

MW:212.20

2,6-Dibromo-Para CresolMW: 265.93

BrBr

CH3

OH

+

129

Mass Balance:

130

51. 3-Chloro2- Methyl Anisole


2,6-Dichlorotoluene is methylated with Sodium Methoxide by using Dimethylsulfoxide (DMSO)

as a solvent. After conversion mass is acidified with HCl .. After isolation and washing , crude

mass is fractionated under vacuum to get pure product.

Chemical Reaction:

Cl

Cl

CH3

+ NaOCH3

Cl

O

CH3

CH3

+DMSO

HCl

2,6-Dichlorotoluene 3-Chloro-2-Methyl anisole

MW: 161.03 MW: 156.60

Sod.Methoxide

MW: 54.02

NaCl

Mass Balance:

131

52. 2-Dimethyl 2 Methyl 1 Propanol


In Autoclave Acetone is reacted with Sodium Cyanide in presence of ammonium bicarbonate

along with methanol solvent to produce 5,5 Dimethyl Hydantoin

In Autoclave 5,5 Dimethyl Hydantoin safonification with caustic to produce to 2-Amino Iso

butyric acid.

2-Amino Iso butyric acid reduction with sodium borohydride along with THF solvent to

produce 2-Amino 2-Methyl propanol.

2-Amino 2-Methyl propanol reacted with formaldehyde & formic acid to produce 2-

Dimethylamino 2-Methyl propanol.

Chemical Reaction:-

132

Mass Balance:

133

53. 4-Hydroxy 3 5 Dimethyl Benzaldehyde


2,6-Xylennol is formylated with Hexamethylene tetra mine(Hexamine) in Acetic solvent to make

product 4-Hydroxy-3,5-dimethyl benzaldehyde. After washing Crude product is purified in

water.

Chemical Reaction:

CH3CH3

OH

+

Hexamethylenetetramine

MW 140.18

Acetic acid

O

CH3CH3

OH2,6-Xylenol 3,5-Dimethyl-4-Hydroxy benzaldehyde

MW: 150.17MW: 122.16

Formylation

134

Mass Balance:

135

54. 2 Ethyl 2 Methyl Butanoic Acid


2,2-dimethyl Butanol is interacted with Formic acid in presence of sulphuric acid to produce of

2-Ethyl ,2-Methyl Butanoic acid

Chemical Reaction:-

+ H2SO4

Formic Acid M.W.=98 2.2-Dimethyl Butanol M.W.=98 2-Ethyl,2-Methyl Butanoic acid M.W =130 Mass Balance:

136

55. 2 2 Dimethyl Butyrl Chloride


This is 4 step reaction. In first step 2- Methyl 2- Butanol and HCl i.e SN1 reaction to form 2-

Chloro Butane. In second step 2- Chloro 2- Methyl Butane is reacted with Sodium Cyanide to

form 2- cyno 2-methyl butane and Hydrolysis of 2- cyno 2-methyl butane to form 2,2- Dimethyl

Butyric Acid after Thionylation 2,2- Dimethyl Butyryl Chloride is obtained.

Chemical Reaction:-

C H 3

OHH 5 C 2 C

CH 3

+ HCl

C H 3

ClH 5 C 2 C

CH 3

Step I

Step II

C H 3

ClCH 3 C

CH 3

+

+ NaCN

C H 3

CNH 5 C 2 C

CH 3

+H 2 O

+ NaCl

Step III

C H 3

CNH 5 C 2 C

CH 3

+ H 2 ONaOH

C H 3

COOHH 5 C 2 C

CH 3

Step IV

C H 3

COOHH 5 C 2 C

CH 3

+ SOCl 2

C H 3

COClH 5 C 2 C

CH 3

+ SO 2+HCl

2,2-DMBC M.W =150

2,2-DMBA M.W.=116

+ NH 3

2,2-DMBA M.W.=1162,2

--DMBCN M.W.=97

2,2--DMBCN M.W.=97

2,2--DMBCl M.W.=77

2,2--DMBCl M.W.=77

2,2--DMBA M.W.=88

137

Mass Balance:

138

56. DV Acid Chloride (60:40 Cistrans)


This is three step process. In first step, D.V. Ester is added to sodium hydroxide solution. After

the reaction the aqueous layer containing sodium salt of D.V. acid is taken to next step. In next

step, Sodium salt of D.V. acid of previous step (in water solution) is added to mixture of dilute

H2SO4 and toluene. D.V. acid formed is dissolved in toluene and sodium sulphate in water. After

the reaction, the layers are separated. The Toluene layer is concentrated and aqueous layer is

sent to further treatment in waste management plant. Crude D.V acid is reacted with Thionyl

chloride in presence of catalyst N-Methyl 2-Pyrrolidinone to form D.V acid chloride . D.V acid

chloride is further distilled in WFE.

Chemical Reaction:-

OCH3Hydrolysis

+ SOCl2

Toluene

Cl

C

Cl

CH

O

Cl

C

Cl

CH OH

O

Cl

C

Cl

CH Cl

O

N-Methyl Pyrollidine

+ SO2

D.V. Acid Methyl ester M.W.=209.11 D.V. Acid M.W.=211.08

D.V. Acid Chloride M.W.=227.5

+HCl

139

Mass Balance:

140

57. Ortho Benzyl Para Chloro Phenol


Process Description:-

This is one step process. Benzyl Chloride is slowly added to Para Chloro Phenol to form

crude Ortho Benzyl Para Chloro Phenol and unreacted Para Chloro Phenol. After reaction

unreated Para Chloro Phenol and also Ortho Benzyl Para Chloro Phenol are distilled out. The

distilled material Ortho Benzyl Para Chloro Phenol is crystallised in Toluene. After Crystallisation

white crystalline powder is obtained.

Chemical Reaction:-

Reaction Scheme of Ortho Benzyl 4-Chloro Phenol

OH

Cl

+

CH2Cl

+

4-Chlorophenol M.W.=128 Benzyl chloride M.W.=128 Ortho Benzyl 4-Chlorophenol M.W.=202

OH

Cl

CH2

HCl

Mass Balance:

141

58. 4-Isopropyl Catechol


4-Isopropyl phenol is brominated to make 2-Bromo-4-Isopropyl phenol by using Hydrobromic acid and

hydrpgen peroxide. After washing this bromo mass is hydrolysed with caustic soda flakes to make

product

4-Isopropyl catechol. After acidification ,product is extracted in N-butyl alcohol.

Organic layer is fractionated to get pure product 4-Isopropyl catechol.

Chemical Reaction:

CH3

CH3

OH

Br

2-Br-4-isopropylphenol

MW = 215.08

+ NaOH

OH

CH3

CH3

OH

4-Isopropyl catechol

MW = 152.19

+ NaBr

Sod.Bromide

MW = 102

CH3

CH3

OH

MW = 136.19

+ HBr + H2O2

CH3

CH3

OH

Br

2-Br-4-isopropylphenol

MW = 215.08

+ H2O

4-Isopropylphenol

4-Hydroxy cumene

142

Mass Balance:

143

59. 1-Adamantyl HCL


This is three step reaction process. In first step Adamantane is chlorinated to form 1-Chloro

Adamantane in presence of catalyst. In Second step 1-Chloro Adamatane to 1- Acetamido

Adamantane in this step H2SO4 is slowly added to 1-Chloro Adamantane , Acetonitrile and

methylene dichloride. In third step 1-Acetamido Adamantane is converted into 1-

Admantaneamine Hydrochloride by using sodium hydroxide solution and methanol in

autoclave.

Chemical Reaction:-

Adamantane M.W.= 136

+ Cl 2

Cl

1-Chloroadamantane M.W.=170

+ HCl

Step I

Step II

Cl

+ CH 3 CN

H 2 SO 4

NH-CO-CH 3

1-Chloroadamantane M.W.=170 1-Acetamidoadamantane M.W.=193

NH-CO-CH 3

+ NaOHHCl

NH 2 .HCl

1-Acetomidoadamantane M.W.=193 1-Adamantaneamine HCl M.W.=187

144

Mass Balance:

145

60. 1-Bromo-2-(3-Chloro-4-Ethoxyphenyl)-2-Methyl Propane


2-Chloro phenol is reacted with Diethyl sulphate in presence of caustic to produce 2-ethoxy

chloro benzene.

2-ethoxy chloro benzene is reacted with 3-bromo-2-methyl-1-propane in presence of Toluene&

methanol by using catalyst zinc dust to produce 1-Bromo-2-(3-chloro-4-ethyxo phenyl)-2-

methyl propane.

Chemical Reaction:-

+

OH

Cl

(C2H5O)2 SO4

OC2H5

Cl

+ Na2SO4

OC2H5

Cl

+ Br

CH3

CH2

CH3

Br

CH3

OC2H5

Cl

2-Chlorophenol M.W.=128 Diethylsulphate M.W.=162 2-Ethoxychlorobenzene M.W.= 156

2-Ethoxychlorobenzene M.W.= 156 3-Bromo,2-Methyl,1-Propane M.W.=135

1-Bromo,2-(3-Chloro,4-ethoxyphenyl )2-Methylpropane M.w.=291 1-Bromo,2-(3-Chloro,4-ethoxyphenyl )2-Methylpropane M.w.=2911-Bromo,2-(3-Chloro,4-ethoxyphenyl )2-Methylpropane M.w.=291

146

Mass Balance:

147

61. 4-Chloro 2,6 Dimethyl Phenyl Acetic Acid


This is four step reaction. In first step 3, 5-Xylidene is converted into 4-Amino 2, 6-Dimethyl

Benzyl Chloride by Para Formaldehyde solution and Hydrochloric Acid. In second step 4-Chloro

2, 6-Dimethyl Benzyl Chloride is Obtained by Diazodisation reaction. In third step 4-Chloro 2, 6-

Dimethyl Benzyl Chloride is converted into 4-Chloro 2, 6-Dimethyl Acetonitrile by Cynatation. In

last step Hydrolysis of 4-Chloro 2, 6-Dimethyl Acetonitrile is converted into 4-Chloro 2, 6-

Dimethyl Phenyl Acetic Acid.

Chemical Reaction:

148

Mass Balance:

149

OH

O

NaBH4+

MW:122.12

4-Hydroxybenzaldehyde (PHB)

Reduction

OH

OH

H2O+

MW :124.13

4-Hydroxybenzylaclohol (PHBL)

Caustic soln

Sod.borohydride

MW:37.83

62. 4-Hydroxy Benzyl Alcohol


PHB reduced with Sodium borohydride in alkaline condition. Mass is acidified and filtered to get

Product 4-Hydroxybenzyl alcohol.

Chemical Reaction:

Mass Balance:

150

63. 2-Methoxy Phenyl Acetone


Addition reaction of 2-anisaldehyde (2-Mehtoxybenzaldehyde) ,Methyl-2-chloropropionate and

Sodium methoxide to make epoxy ester. After conversion, reaction mass is treated with dilute

sulfuric acid to make 2-Methoxyphenyl acetone. After washing, crude mass obtained is

fractionated under high vacuum to get pure product.

Chemical Reaction:

+NaOCH3

o-Anisaldehyde Methyl 2-Cl-Propionate (2CPME)

H

O

OCH3CH3

Cl O

O CH3

H2SO4 / H2O

Epoxy Ester

OCH3

O

CH3

2-Methoxy Phenyl Acetone (2MPA )

H

O

CH3

O

OH

OCH3

MW: 136.14 MW: 122.55

MW: 230 MW: 164.2

H

O

CH3

O

OH

OCH3

Epoxy EsterMW: 230

151

Mass Balance:

152

64. Methyl-2-Dimethyl Amino-2-phenyl butyrare


2-Amino-2-Phenylbutyric acid is converted to Dimethylamino-2-phenyl butyric acid by reacting

with formic acid and formaldehyde solution, After getting desired conversion, caustic solution is

added in reaction mass and sodium salt solution is reacted with Dimethyl sulphate to make

methyl ester i.e product Methyl-2-Dimethylamino-2-phenylbutyrate.

.

Chemical Reaction:

CH3

NH2

O

OH

2-Amino-2-phenylbutyric acid

M.Wt:- 179.21

Sodium hydroxide

2-Dimethylamino-2-phenylbutyric acidM.Wt:- 207.26

CH3

N

O

OH

CH3

CH3

Methyl-2-Amino-2-phenylbutyrate

M.Wt:- 193.24

CH3

CH3

NH2

O

O

Methyl-2-dimethylamino-2-phenyl butyrate

M.Wt:- 221.29

CH3

CH3 CH3

CH3

N

O

O

+

+

-Na2SO4

-CO2

FormaldehydeFormic acid

HCOOH HCHO

MW:- 46 MW:-30

Dimethyl Sulphate

M.Wt:- 126

(CH3)2SO4

Toluene

+

153

Mass Balance:

154

CHO

+ + C l 2B r 22

CHO

B r

2 + 2 HCl

CHO

B r

+

CH 2 OH

CH 2 OH

B r

OHC

O

+ H 2O

B r

OHC

O

+ K O H +

O H

O

O

CH

O

+ H 2O

O

CHO

+

CH2O H

CH 2O H

M eta P henox y B enz aldehy de M .W .= 198

M eta P henox y B enz aldehy de

B enz aldehy de M .W .= 106 M eta B rom o B enz aldehy de M .W .= 185

M E G M .W .= 62M eta P henox y B enz y l ac eta l M .W .= 229

P henol M .W .= 94

M eta P henox y B enz y l ac etal M .W .= 242

M eta B rom o B enz aldehy de M .W .= 185

M eta brom o B enz y l ac eta l M .W .= 229

M E G M .W = 62

65. Meta Phenoxy Benzyl Alcohol


This is four step reaction. In first step Bromination of Benzaldehyde to form Meta- Bromo

Benzaldehyde. In second step Meta-Bromo Benzaldehyde is converted into Meta- Bromo Benzyl

Acetal in presence of Monoethylene Glycol. In third step Potassium Phenate is formed by

Phenol and Potassium Hydroxide and Potassium Phenate in turns react to Meta-Bromo Benzyl

Acetal to form Meta-Phenoxy Benzyl Acetate. Meta-Phenoxy Benzyl Acetate treated with water

to form Meta-Phenoxy Benzaldehyde and which is converted to Meta-Phenoxy Benzyl Alcohol

by Hydrogenation.

Chemical Reaction:-

155

O

CHO

Meta Phenoxy Benzaldehyde M.W.=198

+ H2 O

CH2OH

Meta Phenoxy Benzyl Alcohol M.W.=200

Catalyst

Meta Phenoxy Benzyl Alcohol

156

Mass Balance:

157

66. 4-Bromophenyl Acetic Acid Methyl Ester


4-Bromophenylacetic acid is reacted with Methanol in presence of sulphuric acid to methyl

ester of 4-Bromophenylacetic acid.

Chemical Reaction:

Br

COOH

4-Bromo phenylacetic acid

MW:215.05

+ CH3OH

Br

COCH3

4-Bromo phenylacetic acid methyl ester

MW:213.07

Methanol

H2SO4

MW:32.04

+ H2O

Mass Balance:

158

Cl

+ CH3

NH

O

H + NaHDMF

1-Chloromethyl Naphthalene

M.Wt:- 176.64

Methyl Formamide

M.Wt:- 59.06 Sodium Hydride

M.Wt:- 23.99

CH3

N O

H

N-(Methyl-formyl)methyl Naphthalene

M.Wt:- 199.24

CH3

N O

H

N-(Methyl-formyl)methyl Naphthalene

M.Wt:- 199.24

H2SO4+

M.Wt:- 98.07

Sulfuric Acid

CH3

NH

M.Wt:- 171.23

N-methyl-1-(1-naphthyl)methanamine

NaOH

H2+ + NaCl

+ Na2SO4

CH3

NH

N-methyl-1-(1-naphthyl)methanamine

+ HCl

CH3

NH:HCl

M.Wt:- 207.70

N-methyl-1-(1-naphthyl)methanamine-HCl

Toluene

M.Wt:- 171.23

67. 4-Hydroxy Acetophenone






under partial vacuum. Base is reacted with HCl gas in presence of toluene to make Hydro

chloride salt.

Chemical Reaction:

159

Mass Balance:

160

68. 2-(1-Admantyl)-4-Bromo Anisole


4-Hydroxy Acetophenone is synthesised from Friedalcraft’s reaction of phenol,

monochlorobenzene and acetyl chloride in the presence of aluminium chloride crude 4-

Hydroxy Acetophenone is formed. After purification pure product is obtained.

Chemical Reaction:-

OH

OH

O CH3

+O

CH3

ClAlCl3

MCB

Phenol M.W. =94 Acetyl Chloride M.W.=78 4-Hydroxy Acetophenone M.W.=136

+ HCl

Mass Balance:

161

69. 2-(3-Hydroxy-2-Methyl Propionyl)-aminol-2-methyl-propanol


In first step2-amino isobutyric acid reacted with Methylacrylic Acid to produce Diacid

Intermedaite after isolation of Diacid Intermediate ,In second step Diacid utilised for reduction

byusing sodium Borohydried along with solvent THF to produce 2-(3-hydroxy-methyl

propyl)amino) –2-methyl propanol

Chemical Reaction:-

Mass Balance:

162

70. 4-Bromophenyl Acetic Acid


4-Bromobenzyl bromide is reacted with Sodium cyanide to make 4-Bromobenzyl cyanide.

4-Bromobenzyl cyanide is then hydrolyzed with caustic to make 4-Bromophenylacetic acid.

Chemical Reaction:

Br

CH3

+ Br Br

Br

Br

+ HBr

Br

Br

+Br

CN

+ NaBrNaCN

Br

COOH

+ NH3

Br

CN Hydrolysis

NaOH / water

4-Bromo toluene Bromine 4-Bromo benzyl bromide

AIBN

4-Bromo benzyl bromide 4-Bromo benzyl cyanide

4-Bromo benzyl cyanide 4-Bromo phenylacetic acid

MW:171.03 MW:160 MW:249.94

MW:249.94 MW:196.05

MW:196.05 MW:215.05

Sod .Cyanide

MW:49

163

Mass Balance:

164

71. 2-Amino 2-Methyl Propanol


Acetone is reacted with Sodium Cyanide in presence of ammonium bicarbonate along with

methanol solvent then dosaponification with caustic to produce to 2-Amino Iso butyric acid.

2-Amino Iso butyric acid reduction with sodium borohydride along with THF solvent to

produce 2-Amino 2-Methyl propanol to get pure product after fractional distillation

Reaction Scheme:

M.W =103M.W =58

M.W =103

M.W.=89

165

Mass Balance:

166

72. 2-Bromo-5-Methoxy-Benzoic Acid


To the stirred solution of meta-Anisic acid in ethylene dichloride was added drop-wise liquid

bromine under controlled temperature at 0-5oC over a period of 5 hrs and maintained at 75-

80oC. After completion, cooled the reaction to 0-5

oC, added cold water slowly and filter the

product to afford the pure 2-Bromo-5-methoxybenzoic acid.

Chemical Reaction:

COOH

OMe

meta-Anisic acid

Mol. Wt.: 152.15

COOH

OMe

Br

2-Bromo-5-methoxybenzoic acidMol. Wt.: 231.04

HBr (g)+

Hydrobromic acid (g)

Mol. Wt.: 80.91

+ Br2

Mol. Wt.: 159.81

Bromine

EDCEDC (R)+

Mass Balance:

167

73. 2-Bromo-5-Hydroxy -Benzoic Acid


To the stirred solution of 3-hydroxybenzoic acid in ethylene dichloride was added drop-wise

liquid bromine under controlled temperature at 0-5oC over a period of 5 hrs and maintained at

75-80oC. After completion, cooled the reaction to 0-5

oC, added water slowly and filter the

product to afford the pure 2-Bromo-5-hydroxybenzoic acid.

Chemical Reaction:

COOH

OH

3-Hydroxybenzoic acid

COOH

OH

Br

2-Bromo-5-hydroxybenzoic acidMol. Wt.: 217.02

HBr (g)+

Hydrobromic acid (g)

Mol. Wt.: 80.91

+ Br2

Mol. Wt.: 159.81

Bromine

EDCEDC (R)+

Mol. Wt.: 138.12

Mass Balance:

168

74. Diphenylmethane-bis-4,4’-N,N’-ethylene Urea (DEU)


Hydrochloride salt of Monoethanolamine is prepared and after removal of water, salt is

chlorinated with Thionyl chloride in presence of toluene to make 2-Chloroethanamine HCl salt

.After quenching in water ,toluene is separated and bottom aqueous layer is reacted with

caustic solution to make Ethyleneimine. Ethyleneimine is distilled off under vacuum.

Ethyleneimine (D) is coupled with 4,4’-Diphenylmethane di isocyanate (MDI) in presence of

toluene to make product Diphenylmethane-bis-4,4'-N,N'-ethylene Urea (DEU.)

Chemical Reaction:

N H 2OH

Monoethanolamine

+ SOCl 2

Thionyl chloride

HCl NH 2 HClC l

2-Chloroethanamine:HCl salt

MW:61.08 MW:119 MW:115.99

NH 2 HClC l


MW:115.99

+ 2 NaOHN H

+ 2 NaCl

Toluene

Ethyleneimine

MW:43.07

N H

Ethyleneimine

MW:43.07

+N

C

N

C

OO Toluene

N H N H O

O N

N

4,4'-Diphenylmethane di isocyanateI(MDI)

DEUDiphenylmethane-bis-4,4'-N,N'-ethylene Urea

MW;336.39

MW;250.25

2 x

+ +SO 2 HCl

169

Mass Balance:

170

75. TrimethylolpropaneTris(2-methyl-1-aziridinepropionate)


Hydrochloride salt of Isopropanolamine is prepared and after removal of water, salt is

chlorinated with Thionyl chloride in presence of toluene to make 2-Chloropropylamine HCl salt

.After quenching in water, toluene layer is separated and aqueous layer containing 2-

Chloropropylamine HCl salt , is reacted with caustic solution to make propyleneimine.

Propyleneimine is distilled off under vacuum.

Proyleneimine(D) is then coupled with Trimethylpropane triacrylate to make product POLY

x100. Propyleneimine and other low boilers are removed under vacuum.

Chemical Reaction:

NH2OH

Isopropanolamine

+ SOCl2

Thionyl chloride

HCl NH2 HClCl

2-Chloropropylamine:HCl salt

MW:75.11 MW:119 MW:130.02

NH2 HClCl

2-Chloropropylamine:HCl salt

MW:130.02

+ 2 NaOHNH + 2 NaCl

Toluene

Propyleneimine

MW:57.09

NH

Propyleneimine

MW:57.09

+ OO

O

O

O

O

Trimethylolpropane triacrylate

MW:296.32

TEA 4-Methoxyphenol

Dicyclohexylcarbodiimide(DDC)O

OO

O

O

O

N

N

N

POLY X 7

Trimethylolpropane tris(2-methyl-1-aziridinepropionate)

MW:467.60

(TMPTA)

3 x

+ +SO2 HCl

171

Mass Balance:

172

76. PentaerythritolTris([3-(1-aziridinyl)propionate]


Hydrochloride salt of Monoethanolamine is prepared and after removal of water, salt is

chlorinated with Thionyl chloride in presence of toluene to make 2-Chloroethanamine HCl salt.

After quenching in water, bottom aqueous layer of 2-Chloroethanamine HCl salt is reacted with

caustic solution to make Ethyleneimine. Ethyleneimine is distilled off under vacuum.

Ethyleneimine is coupled with Pentaerythritol triacrylate (PETA) to make product

Pentaerythritol tris[3-(1-aziridinyl)propionate] or POLY x 7. Ethyleneimine and other low boilers

are removed under vacuum.

Chemical Reaction:

NH2

OH

Monoethanolamine

+ SOCl2

Thionyl chloride

HCl

NH2 HClCl

2-Chloroethanamine:HCl saltMW:61.08 MW:119 MW:115.99

NH2 HClCl


MW:115.99

+ 2 NaOHNH + 2 NaCl

Toluene

Ethyleneimine

MW:43.07

NH

EthyleneimineMW:43.07

+

OH

OO

O

O

O

O

Pentaerythritol triacrylate(PETA)MW:298.29

TEA ,4-Methoxyphenol

Dicyclohexylcarbodiimide(DDC)

OH

O

OO

O

O

O

N

N

N

POLY X 7Pentaerythritol tris[3-(1-aziridinyl)propionate]

MW:427.49

3 x

+ +SO2 HCl

173

Mass Balance:

174

77. 2-Bromophenyl Acetonitrile


2-Bromobenzyl bromide is reacted with Sodium cyanide in presence of toluene and tetrabutyl

ammonium bromide as a catalyst to make 2-Bromophenylacetonitrile.

Chemical Reaction:

Br

Br

+CN

Br+ NaBrNaCN

2-Bromophenylacetonitrile

MW:249.94 MW:196.05

Sod .Cyanide

MW:49

2-Bromobenzyl bromide

Toluene

TBAB

Mass Balance:

175

78. Phenyl Acetic Acid Ethyl Ester


Phenyl acetic acid is interacted with ethanol by using Catalyst Sulphuric acid ,after desire

conversion the unwanted ethanol is recovered by simple distillation & collect the crude

bottam material for neutralization using sodium bicarbonate then final material will be rectify

in fractional distillation to get desire purity of phenyl acetic acid ethyl ester .

Reaction Scheme:

CH2COOH

+ C2H5OHH2SO4

CH2COOC2H5

+ H2O

Phenyl acetic acid Ethanol Phenyl Acetic acid ethyl ester

Mass Balance:

176

79. 3-Methoxy, 2-Methyl Benzoyl Chloride


3-hydroxy,2-Methyl Benzoic acid is methylated with dimethyl sulphate in presence of Caustic

to Produce 3-Methoxy,2-Methyl Benzoic acid ,same material is purified make it sodium salt &

acidified to produce Pure material of 3-Methoxy ,2-methyl Benzoic acid . This acid is

interreacted with Thionyl chloride to produce Pure 3-Methoxy ,2-Methyl Benzoyl chloride

REACTION SCHEME

OH

CH3

COOH

3-Hydroxy,2-Methyl Benzoic Acid

M.W.=154

+ (CH3)2SO4

NaOH

OCH3

CH3

COOH

+ Na2SO4

3-Methoxy,2-Methyl Benzoic acid

M.W.=168

OCH3

CH3

COOH

3-Methoxy,2-Methyl Benzoic acid

M.W.=168

+ SOCl2

OCH3

CH3

COCl

3-Methoxy,2-Methyl Benzoyl Chloride

M.W.=186

+SO2 + HCl

177

Mass Balance:

178

80. Methyl (E)-3-methoxy-2-(2-chloromethylphenyl)-2-propenoate


This is three step reaction. In first step is Chlorination of 2-Methyl phenyl acetic acid to produce

2-chloromethyl phenyl acetic acid & in second step 2-Chloromethyl phenyl acetic acid reacted

with thionyl chloride along with Methanol to Produce Methyl 2- ( 2-Chloromethyl ) phenyl

Acetate (MCMPA )

The third step the MCMPA reacted with methyl format in presence of sodium Methoxide using

solvent Xylene then further proceed for methoxylation by using K2Co3 & Dimethyl sulphate to

produce the desire final compound Methyl (E) 3-Methoxy-2-( 2-Chloromethyl Phenyl)-2-

Propenoate.

Chemical Reaction:-

CH2COOH

CH3

2-Methyl Phenyl acetic Acid (OMPAA)

M.W.=150

+ Cl2

CH2COOH

CH2Cl

2--Chloromethyl Phenyl acetic Acid (CMPAA)

M.W.= 184

+ HCl

CH2COOH

CH2Cl

+ SOCl2 + SO2 + HCl

2-Chloromethyl phenyl acetic acid (CMPAA)

CH2COOCH3

CH2Cl

Methyl 2-(2-Chloromethyl Phenyl Acetate) (MCMPA )

M.W.=184M.W.=185

Step I (CMPAA)

Step II (MCMPA)

179

CH2COOCH3

CH2Cl

+ HCOOCH3

CH3ONa

Xylene

/ HCl

H3COCH

CH2Cl

CO

O

CH3

2-Chloromethyl Phenyl Methyl Acetate (MCMPA)

Methyl Formate M.W.=60

M.W.=198.6

Methyl (E) 3-Methoxy-2-( 2-Chloromethyl Phenyl)-2-Propenoate

M.W.=240.68

180

Mass Balance:

181

81. 2-(2-hydeoxyphenyl)-3-methoxypropenoic acid methyl ester


2-Hydroxy Phenyl acetic acid reacted with methanol in presence of sulphuric acid to produce

2-Hydroxy Phenyl Acetic acid methyl ester then ester is interacted with Methyl formate in

presence of sodium Methoxide to produce the desire product 2-(2-hydroxyphenyl)-3-

methoxypropenoic acid methyl ester

Reaction Scheme :

CH2COOH

OH

+ CH3OHH2SO4

CH2COOCH3

OH

+H2O

2-Hydroxy Phenyl Acetic acid

M.W.1522-Hydroxy Phenyl Acetic acid Methyl ester

M.W.=166

CH2COOCH3

OH

2-Hydroxy Phenyl Acetic acid Methyl ester

M.W.=166

+ HCOOCH3

CH3ONa

HCl

C -COOCH3

OH

CH2

OH3C

Methyl -2-(2'-2-Hydroxy Phenyl)-3-Methoxyacrylate

M.W. 208

182

Mass Balance:

183

82. Methyl (2E) -2-( 2-(6-(2-Cyanophenoxy )Pyrimidine -4yl)Oxy ) Phenyl Acetate


2-hydroxy Phenyl Acetic acid (OHPAA) is reacted with Methanol in presence of Acid to produce

2-Hydroxy Phenyl methyl Acetate ( OHPM). This ester is reacted with 4,6-Dichloro Pyrimidine

& 2-Cyano Phenol in presence of K2CO3 ,DMS using solvent Xylene to produce final product

Methyl (2E) -2-( 2-(6-(2-Cyanophenoxy )Pyrimidine -4yl)Oxy ) Phenyl Acetate.

Chemical Reaction:

184

Mass Balance:

185

83. 3-CHLORO-4-METHYLISOPROPYL BENZOATE


Charge para toluic acid ,TPP and added Thionyl chloride from top, maintain reaction mass,

distilled out para toluoyl chloride, chlorinate para toluoyl chloride with ferric chloride and

chlorine gas, distilled out 3-chloro para toluoyl chloride using vacuum, add Isopropyl alcohol

and make crude ester of Isopropyl-3-chloro 4-methyl benzoate. Distilled out crude product for

high purity.Final product pack in drums.

Chemical Reaction:

OHO

C lO

para Toluic Acid TC

TPP

FeCl3

C lO

C l

OH

para Toluoyl chloride

Cl--para Toluoyl chloride IPA

C lO

C lO

C l

para Toluoyl chloride

OO

C l

Cl--para Toluoyl chloride

Isopropyl-3-Cl 4-Me Benzoate

(ICMB)

+ SOCl2 + SO2 + HCl

+ Cl2 + HCl

+ + HCl

STEP-I THIONYLATION

STEP-II CHLORINATION

STEP-III ESTERIFICATION

REACTION SCHEM:--

mw = 136 mwt=119 mw=154.5

mw=154.5 mw=189

mw=189mw=212.5mw=60

186

Mass Balance:

187

Annexure – IV

Details of water consumption & waste water generation

Water consumption

Sr.

No.

Usage Water Consumption in KL/Day

As per EC No. F. No. J-

11011/132/2014-IA II (I)

and CTE No. 70398

Additional Total after proposed

Expansion

1. Domestic 15 +10 25

2. Gardening 6 +24 30

3. Industrial

Process &

Washing

80 +140 220

Boiler 20 +60 80

Cooling 20 +200 220

Cleaning 3 +22 25

Scrubber 10 +20 30

Total(Industria

l)

133 +442 575

Total

(Domestic +

Industrial+

Gardening)

154 +476 630

188

Wastewater Generation

Sr.

No.

Usage Waste Water Generation in KL/Day

As per EC No. F. No.

J-11011/132/2014-

IA II (I) and CTE No.

70398

Additional Total after proposed

Expansion

1. Domestic 12 8 20

2. Gardening -- -- --

3. Industrial

Process &

Washing

70 130 215

Boiler 5 40 45

Cooling 6 24 30

Scrubber 10 20 30

Cleaning 3 22 25

Total

(Industrial)

94 236 345

Total

(Domestic +

Industries)

106 244 365

189

Water Balance

Process /

Washing-

220 KL/Day

Raw Water = 630 KL /Day

Boiler-

80 KL/Day

Cooling Tower-

220 KL/Day (50 KLD

fresh + 170 KLD

Reuse)

Cleaning-

25 KL/Day

Domestic-

25 KL/Day

Gardening

30 KL/Day

200

KL/Day

45 KL/Day 30 KL/Day

25 KL/Day

20 KL/Day

to ETP

ETP

330 KL/Day

GIDC Drain

365 KL/Day

MEE Condensate -165 KLD

KLKLL13125/KL/DayKL/Day

MEE

MEE Salt 2.5 MT/Day

To TSDF

150 KL/Day -Primary ETP

Scrubber

30 KL/Day

190

Annexure – V

Details of Effluent Treatment Plant TREATMENT SCHEME

FOR HIGH TDS & COD STREAMS (150 KLD)

High TDS &high COD containing streams from process will be collected through bar Screen Chamber (SC-

01)where bar screen will be installed to screen out coarse solids particles like plastics, bottles etc. from

where it will enter into Oil & Grease Trap(OGT-01), where floating oil & grease is removed manually and

collected in O & G Collection Tank (OGCT-01). From Oil & grease trap the effluent will enter in two nos.

of Equalizationcum Neutralizationtank (ENT-01) in a batch wise manner where pH will be neutralized by

adding Acid/Caustic from Acid (ACDT-01) /Caustic Dosing Tank (CDT-01) as per requirement.In ENT-01,

coarse bubble diffuser will be provided for mixing and to keep solids in suspension and air shall be

supplied by Air Blowers (B-01).

This effluent will be pumped to Flash Mixer(FM-01) where Alum and Poly shall be added from Alum

(ADT-01) and Poly Dosing Tanks (PDT-01) respectively. Then effluent is collected in PrimaryClarifier-

1(PCL-01)where Suspended and coagulated solids shall be settled at bottom. Then solids are sent to

Sludge Sumpand clear supernatant will overflow into the MEE Feed Tank (MFT-01)from where it will be

pumped to Multiple Effect Evaporator (MEE). MEE will be designed to treat 150 m3/d of waste water.

Then primarily treated waste water will be pumped to the 1st

effect Evaporator calendria. The high-

pressure steam from the boiler will be put in the TVR inlet. The TVR will suck the vapors from the 1st

effect VLS and the outlet of TVR will have steam at intermediate pressure and increased enthalpy. The

outlet steam from the TVR will be used as the heating medium for the 1st

effect calendria. The mass will

then be recirculated in the Vapor Liquid Separator (VLS). The vapors separated in the 1st

effect VLS will

be partly used as heating medium for the 2nd

effect calendria and partly will be sucked by the TVR. The

vapors separated in the 2nd

effect VLS will be used for heating for the third effect calendria. The vapors

separated in the 3rd

effect VLS will be used for heating for the fourth effect calendria. The vapors

separated in the 4th

effect VLS will be condensed in the condenser with cooled water and collected in the

flash pot. The steam or vapor in each effect will get condensed and get collected in the flash pot. From

the flash pot the condensate will be pumped to the condensate tank. The concentrated feed in the

4th

effect VLS will be pumped to the pusher centrifuge for recovery of the salt. Filtrate from centrifuge

will be pumped to 4th

effect back.

FOR LOW COD & TDS STREAMS (180 KLD) + 165 KLD MEE CONDENSATE + 20 KLD DOMESTIC

Primary Treatment

Cooling tower and boiler blow downs, low COD & TDS Effluent, cleaning water and scrubber tail will be

collected through pipelines from the manufacturing area to equalization Tank at ETP. Dilute streams will

be entering to bar Screen Chamber (SC-02) where bar screen will be installed to screen out coarse solids

particles like plastics, bottles etc. From the bar screen effluent will enter Oil & Grease Trap (OGT-02),

where floating oil & grease is removed manually. From Oil & grease trap the effluent will enter

Equalization cum Neutralization Tanks-2 (ENT-02). The equalization tank is provided with alkali dosing &

acid dosing from Acid (ACDT-01)/Caustic Dosing Tanks (CDT-01) as per requirement for pH neutralization

& coarse bubble diffuser will be provided to mix the wastewater. For that air shall be supplied by Air

Blowers (B-02).

191

This effluent will be pumped to Flash Mixer(FM-02) where Alum shall be added from Alum Dosing Tanks

(ADTs-01). Overflow FM shall be collected in Flocculator (FLC-01) where Poly shall be added from Poly

Dosing Tanks (PDT-01). Then effluent is collected in Primary Clarifier-2 (PCL-02) where Suspended and

coagulated solids shall be settled at bottom. Then solids are sent to Sludge Sump and clear supernatant

will overflow to Aeration Tank-1 (AT-01).

Secondary treatment:

Clear supernatant from Primary Clarifier shall be passed in Aeration Tank-1 (AT-01). Here, condensate from

MEE shall be added to AT-01. Biodegradation of organic matter of the wastewater shall be carried out by

bacteria (suspended growth) in the AT-01. The aeration tank provides proper mixing and supplies oxygen to

the microorganisms in the dissolved form through the fine bubble diffusers. Also MLSS and MLVSS ratio

shall be maintained to ensure active microorganisms growth. Various nutrients like Urea and DAP shall be

added from Nutrient Dosing Tanks (NDTs-01) regularly so as to ensure proper growth of the

microorganisms. Oxygen shall be supplied by 2 nos. of air blowers (B-03) through diffusers. Air blowers also

keep MLSS in suspension. Due to Nitrification process in Aeration Tank-2, pH of effluent will go down in AT-

02.

Then the overflow of the aeration tank shall be diverted into the Secondary Clarifier-1 (SCL-01) for biomass

separation. An appropriate retention time is given to the effluent to ensure proper settling. The sludge

settles down into the bottom of the SCL-01 and required amount of settled sludge shall be recycled back

into the aeration tank to maintain desired concentration of biomass. Excess biomass shall be pumped to

sludge sump (SS-01).

Then after, overflow (clear supernatant) of SCL-01 shall be collected Aeration Tank-2 (AT-02). Here, again

biodegradation of left out organic matter of the wastewater shall be carried out by bacteria (suspended

growth) in the AT-2 and for that oxygen shall be supplied by two nos. of blowers (B-03) with help of

diffusers. Then after, wastewater shall go to Secondary Clarifier-2 (SCL-02) from AT-02. Here, the suspended

solids shall be settled. Activated sludge shall be removed from bottom of SCL-02 and pumped to AT-02 to

maintain MLSS and remaining will be sent to SS. Nutrients will be added from NDTs-01 to Aeration Tank-2

for growth of Bacteria.

Tertiary treatment

Then after, overflow (clear supernatant) of SCL-2 shall collected in Intermediate Sump(IS-01).Then effluent

from the IS shall be pumped to the Pressure Sand Filter (PSF-01) and Activated Carbon Filter (ACF-01) for

tertiary treatment. The effluent shall enter into the sand filter from the top and the filtered effluent shall be

further passed to the Activated Carbon Filter for polishing treatment. A back wash facility shall be provided

to the sand filter and carbon filter to wash out the suspended solid whenever required. For backwash, the

effluent from the Intermediate Sump shall be pumped at the bottom of the sand filter (and / or carbon

filter) and the discharge of the sand filter (and / or carbon filter) shall be diverted into the Equalization cum

Neutralization Tank. Treated Effluent from ACF-01 shall be collected in Treated Water Sump (TWS-01)

before sent to GIDC drain.

Sludge Dewatering System

The primary and secondary sludge from PST-01, PCL-01, SCL-01 & SCL-02 shall be collected in Sludge Sumps

(SS-01). From SSs-01 it shall be pumped to the Filter Presses (FP-01) for sludge dewatering. We will provide

192

two nos. Filter presses to use alternately. The sludge cake shall be collected and packed into the plastic bags

and stored in the HWSA for ultimate disposal to TSDF. The leachate from the FP-01 shall be collected in

Drain Pit and then pumped back to collection cum equalization cum Neutralization Tank-2 (ENTs-02) for

further treatment.

DESIGN PARAMETERS

A) MULTIPLE EFFECT EVAPORATOR (HIGH COD & TDS):

Parameters Unit

Raw Effluent

(High COD &

TDS)

After

Primary treatment

Outlet of Evaporator

(Condensate including

live steam Condensate)

Design Quantity m3/day 150 150 165

pH ---- 2- 8 7.5 – 8.0 7.5 - 8.0

COD mg/L <90000 <80000 <6000

TSS mg/L <6000 <70 <20

TDS mg/L <180000 <180000 <100

Chlorides mg/L <85000 <85000 <70

Ammonical N mg/L <250 <250 <50

B) ETP (MEE CONDENSATE & LOW COD & TDS):

Parameters Unit Raw Dilute

Streams

Condensate

from

MEE

Equalization

Tank

(Dilute

streams +

Condensate

from MEE +

Domestic)

Outlet from

Primary

Outlet

from

Secondary

Outlet from

Tertiary

(Final Treated

Waste Water)

Design

Quantity m

3/day 180 165 365 365 365 365

pH ---- 5.5 – 6.5 7.5 – 8.0 7.5 – 8.0 7.5 – 8.0 7.5 – 8.0 7.5 – 8.0

BOD3, 270C mg/L <1000 <1000 <1000 <800 < 100 <100

COD mg/L <1500 <6000 <3500 <2800 < 300 <250

TSS mg/L <2000 <5 <800 <500 < 70 <50

TDS mg/L <5000 <100 <2500 <2300 <2100 <2100

Chlorides mg/L < 2500 <70 <1200 <1100 <1000 <1000

Oil & Grease mg/L < 20 Nil <10 <10 <10 <10

Ammonical

N mg/L <40

<50 <50 <50 <20 <20

193

DETAILS OF UNITS FOR PROPOSED EFFLUENT TREATMENT PLANT

Sr. No. Description Qty Capacity MOC Remark

HIGH TDS AND COD STREAMS (150 KLD)

1. Screen Chamber-1 (SC-01) 1 No. 0.6 m3

RCC M25- AR

Tiling/FRP New

2. O&G Trap-1 (OGT-01) 1 No. 7.5 m3

RCC M25- AR

Tiling/FRP New

3. O & G Collection Tank-1 1 No. 1.0 m3

RCC M25- AR

Tiling/FRP New

4. Equalization cum Neutralization

Tanks-1 (ENTs-01) 2 Nos. 75 m

3 each

RCC M25-Tile

Tiling/FRP New

5. Caustic Dosing Tanks (CDTs-01) 3 Nos. 15000 Lit. HDPE New

6. Acid Dosing Tank (ACDT-01) 1 No. 1500 Lit HDPE New

1 Alum Dosing Tank (ADTs-01) 2 Nos. 3000 Lit HDPE New

2 Poly Dosing Tank (PDT-01) 1 No. 1000 Lit HDPE New

3 Flash Mixer-1 (FM-01) 1 No. 5.0 m3 RCC M25 New

4 Primary Clarifier (PCL-01) 1 No. 37.5 m3 RCC M25 New

5 Sludge Sump (SS-01) 2 No. 27 m3 RCC M25 New

6 Poly Dosing Tank-2 (PDT-02) 1 No. 1000 Lit HDPE New

7 Filter Press (FP-01) 2 No.

To handle 1500

kg/day of wet

cake basis each

PP Plates+ MS

Frame

New

8 ME Feed Tank (MFT-01) 1 No. 75 m3 RCC M25 New

9 Multiple Effect Evaporator 1 No. 150 KLD

SS/As per

specification given

below

New

10 Condensate Tank (CNT-01) 1 No. 50 m3 RCC M25 New

194


LOW COD + LOW TDS STREAMS (180 KLD) UTILITIES + (165 KLD) MEE CONDENSATE + (20 KLD) DOMESTIC

11 Screen Chamber-2 (SC-02) 1 No. 0.6 m3

RCC M25- AR

Tiling/ FRP New

12 O&G Trap-2 (OGT-02) 1 No. 7.5 m3

RCC M25- AR

Tiling/ FRP New

13 O & G Collection Tank-2(OGCT-02) 1 No. 1.0 m3

RCC M25- AR

Tiling/ FRP New

14 Equalization cum Neutralization

Tanks-2 (ENTs-02) 2 Nos. 172.5 m

3 each

RCC M25-Tile

Tiling/ FRP New

15 Flash Mixer-2 (FM-02) 1 No. 10.0 m3 RCC M25 New

16 Flocculator (FLC-01) 1 No. 10.0 m3 RCC M25 New

17 Primary Clarifier-2 (PCL-02) 1 No. 85 m3 RCC M25 New

18 Nutrient Dosing Tanks (NDTs-01) 2 No. 1000 Lit HDPE New

19 Aeration tank-1 (AT-01) 1 No. 536 m3 RCC M25 New

20 Secondary Clarifier-1 (SCL-01) 1 No. 100 m3 RCC M25 New

21 Aeration Tank-2 (AT-02) 1 No. 239 m3 RCC M25 New

22 Secondary Clarifier-2 (SCL-02) 1 No. 80 m3 RCC M25 New

23 Intermediate Sump (IS-01) 1 No. 45 m3 RCC M25 New

24 Pressure Sand Filter (PSF-01) 1 No 1.4 dia x 1.5 m

Ht

MSEP New

25 Activated Carbon filter (ACF-01) 1 No 1.4 Diax 1.5 m

Ht

MSEP New

26 Treated Water Sump (TWS-01) 1 No. 175 m3 RCC M25 New

Common Facilities

27 Hazardous Waste Storage Area

(HWSA-01) 1 No. As Required

RCC M25+BKMS New

28 Chemical Storage Room 1 No. As Required RCC M25+BKMS New

29 MCC & PLC Room 1 No. As Required RCC M25+BKMS New

195


30 Laboratory 1 No. As Required RCC M25+BKMS New

RCC M25/M20 = Reinforced Cement Concrete (M 25/M20 Grade)

BKMS = Brick Masonry

MSEP = Mild Steel Epoxy painting

HDPE = High Density Poly Ethylene

SS 304/316 = Stainless Steel 304/316 grade

SPECIFICATIONS FOR MULTI STAGES EVAPORATOR

Sr.

No. Item Name Qty. MOC

Fabricated Items

1 Balance tank 1 No. SS – 316

2 Preheater 5 Nos.

Tubes – SS 316 Ti Seamless,

Shell – SS – 304

Tube Sheet – SS – 316

Dome – SS – 316

3 Evaporator Calendria 4 Nos.

Tubes – SS 316 Ti Seamless,



Dome – SS – 316

4 Vapour Separators 4Nos. SS – 316

5 Flash Pot 1 No. SS – 304

6 Surface Condenser 1 No.

Tubes – SS – 304 Seamless,



Dome – SS – 304

7 Salt Settler 1 No. SS – 316

8 Seal Water Cooling Tank 1 No. MS – Epoxy

9 Filtrate Collection Tank 1 No. SS – 316

10 Vacuum Water Collection

Tank 1 No. MS – Epoxy

Bought Out Equipments

1 Feed Pump 1 No.

Casing: SS – 316

Impeller: SS – 316

Shaft: AISI – SS – 316

196

Sr.

No. Item Name Qty. MOC

2 Recirculation Pumps 4 Nos.

Casing: ASTM A351 Gr CF8M

Impeller: ASTM A351 Gr CF8M

Shaft: ASTM A TP276 SS316

3 Thermo

VapourRecompressor 1 No.

Body: CS

Nozzle: SS – 304

4 Condensate pump 1 No.

CI Suction and Discharge with SS –

304 internals

5 Seal water Cooling Pump 1 No. CI Suction and Discharge with SS –

304 internals

6 Product Pump 1 No.

Casing: SS – 316



7 Filtrate Transfer pump 1 No.

Casing: SS – 316



8 PHE 1 No. SS Plates with MS Mounting Frame

9 Vacuum Pump 2 Nos.

Casing, Cover: C.I. IS 210 FG 260


Shaft: SS – 316

10 Vacuum Tank

Recirculation pump 1 No.

Casing: CI

Impeller: CI

Shaft: CI

11 Pusher Centrifuge 1 No. SS

12 Piping Lot

Vapour& condensate lines – SS –

304

Liquid Lines – SS – 316

13 Electricals Lot Suitable as per below notes

14 Instrumentation and PLC

System 1 No. Suitable as per below notes

15 CIP Tank with Agitator 1 No. Tank: PP – FRP

Agitator: SS – 316

16 CIP Pump 1No. PP

197

Cooling Tower

Sr. No. Item Name Qty. MOC

Cooling Tower and Accessories

1 Cooling Tower 1 No.

FRP – 280 TR

2 Cooling Tower Pumps 2 Nos.

Casing: CI

Impeller: CI

Shaft: CI

3 Piping Lot MS

ELECTRICAL LOAD LIST

A) Multiple Effect Evaporators:

Connected Load 144 H.P.

Operating Load 129 H.P.

B) ETP – High COD & TDS:



C) ETP – Low COD & TDS:



D) AREA REQUIRED

Multiple Effect Evaporators: 18m (L) x 10m (W) M2

ETP for High COD & TDS: 30m (L) x 15m (W) M2

ETP for Low COD & TDS: 49m (L) x 33m (W) M2

198

Process Flow Diagram for Effluent Treatment Plant

199

Annexure – VI

Details of Solid & Hazardous Waste generation and disposal

Sr.

No.

Type of

Hazardous

Waste

Category

No.

Quantity

as per EC

Additional Total Quantity

after

proposed

expansion

Treatment & Disposal

1.

ETP Sludge 35.3 30

MT/Mont

h

+20

MT/Month

50 MT/Month Collection, storage,

transportation

,Disposal to Nearest

TSDF site

2.

Residue from

Distillation

36.1 65

MT/Mont

h

+30

MT/Month


transportation, Co-

processing in Cement

Industries or send to

Nearest Common

Incineration Site

3.

Discarded

Drum

33.1 1000

Nos./Mo

nth

+2000

Nos./Mont

h

3000

Nos./Month

Collection, storage,

transportation, Sell to

GPCB authorized

Vendor after

decontamination

4.

Discarded PP

Bags/Liner

33.1 2000

Nos./Mo

nth

+2000

Nos./Mont

h

4000

Nos./Month



GPCB authorized

Vendor after

decontamination

5.

Used Oil 5.1 200

Liters/Mo

nth

+300

Liters/Mont

h

500

Liters/Month



GPCB registered

reprocessor.

6.

Inorganic Salts 29.1 100

MT/Mont

h

-50

MT/Month



end user or disposal in

TSDF

7.

Carbon Sludge 28.3 5

MT/Mont

h

-- 5 MT/Month Collection, storage,

transportation,

Disposal at Nearest

TSDF Site

8.

MEE Salt -- 25

MT/Mont

h

+275

MT/Month

300

MT/Month


transportation,

Disposal at Nearest

TSDF Site

9. HCl (30%) 29.6 126

MT/Mont

h

-- 156

MT/Month



end user

10 H2SO4 (70%) 29.6 50 -30 20 MT/Month Collection, storage,

200

MT/Mont

h

MT/Month transportation, Sell to

end user

11. Liqour

Ammonia

(24%)

-- 45

MT/Mont

h

+10

MT/Month



end user

12. HBr

(35-40%

Solution)

B26 70

MT/Mont

h



end user

13. NaBr

(18-20%

Solution)

B26 76

MT/Mont

h



end user

14. Phosphoric

Acid

(30-

35%Solution)

29.3 60

MT/Mont

h



end user

15. Copper

Sulphate/

Copper

Oxide/Hydroxi

de

C1 80

MT/Mont

h

-40

MT/Month



end user

16. Sodium

Acetate

-- 5

MT/Mont

h



end user

17. Sodium Sulfite

18-20%

-- 30

MT/Mont

h

+30

MT/Month



end user

18. Potassium

Chloride

-- 5

MT/Mont

h

-5

MT/Month

-- Collection, storage,


end user

19. Potassium

Carbonate

-- 12

MT/Mont

h



end user

20. Ammonium

Sulphate

C1 4

MT/Mont

h

-4

MT/Month

-- Collection, storage,


end user

21 Spent Solvent -- -- 50 KL/

Month

50 KL/ Month Collection, storage,


Cement Industry

22 Poly Aluminum

Chloride

solution 25%

-- -- +20

KL/Month

20 KL/Month Collection, storage,


end user

23 Boiler/Fly Ash -- -- +100

MT/Month

100

MT/Month


transportation &

given to Bricks

Manufacturers / Land

filling

201

Annexure – VII

Details of Stack & Vent

Flue Gas Emissions

Sr.

No

Stack attached

to

Fuel &

Consump

tion

Stack

Height

in

meter

Stack

Diame

ter in

mm

APCM Probable

Pollutants

Permissible

Limit

As per EC No. F. No. J-11011/132/2014-IA II (I) and CTE No. 70398

1. Thermic Fluid

Heater

Natural

Gas

25 1000 -- SPM

SO2

NOX

150 mg/NM3

100 ppm

50 ppm

2. Steam Boiler

(Coal Fired FBC

based system)

6 TPH

Coal/Briq

uette

35 1000 Multi

Cyclon

e+ Bag

Filter

SPM

SO2

NOX

150 mg/NM3

100 ppm

50 ppm

3. D.G.SET

(500 KVA)

Diesel 11 200 SPM

SO2

NOX

150 mg/NM3

100 ppm

50 ppm

After Proposed expansion

1. Thermic Fluid

Heater

Coal/Briq

uette

45 1400 MDC +

Bag

Filter

SPM

SO2

NOX

150 mg/NM3

100 ppm

50 ppm

2. Steam Boiler

(Coal Fired FBC

based system)

8 TPH

Coal/Briq

uette

45 1400 ESP SPM

SO2

NOX

150 mg/NM3

100 ppm

50 ppm

3. D.G.SET (1500

KVA)

Diesel 11 350 --- SPM

SO2

NOX

150 mg/NM3

100 ppm

50 ppm

202

Process Emission

Sr.

No.

Stack attached

to

Stack

Height in

meter

Stack

Diameter

APCM Probable

Pollutants

Permissible

Limit

As per EC No. F. No. J-11011/132/2014-IA II (I) and CTE No. 70398

1. Reaction Vessel 12 300 Two Stage

Water Alkali

Scrubber

HBr

Scrubber

HCl

SO2

HBr

20 mg/Nm3

40 mg/Nm3

5 mg/Nm3


Alkali

Scrubber

HCl 20 mg/Nm3


Water Alkali

Scrubber

HCl

SO2

20 mg/Nm3

40 mg/Nm3

After Proposed expansion

1. Reaction Vessel 12 300 Three Stage

Water Alkali

Scrubber

HBr

Scrubber

HCl

SO2

HBr

20 mg/Nm3

40 mg/Nm3

5 mg/Nm3


Alkali

Scrubber

HCl 20 mg/Nm3


Water Alkali

Scrubber

HCl

SO2

20 mg/Nm3

40 mg/Nm3


Water/

sulphuric

Scrubber

NH3 175 mg/Nm3

203

Annexure – VIII

Details of Hazardous Chemicals Storage & Handling

Sr.

No. Name of Hazardous Chemical Type MOC Size KL No Dimension

1 Formaldehyde Liquid CS Tank 25 KL 2 3.0 M X 3.8 M

2 Iso Propyl Alcohol Liquid C S Tank 25 KL 1 3.0 M X 3.8 M

3 Ethel Acetate Liquid C S Tank 25 KL 2 3.0 M X 3.8 M

4 Ethylene Di Chloride Liquid C S Tank 25 KL 2 3.0 M X 3.8 M

5 MDC Liquid C S Tank 25 KL 1 3.0 M X 3.8 M

6 HCL Liquid PP/FRP Tank 25 KL 2 2.7 M X 3.5 M

7 Caustic Soda Lye Liquid CS Tank 25 KL 1 2.7 M X 3.5 M

8 Bromine Liquid MS GLR Tank 10 KL 1 10 K L VOLUEM

9 Bromo Anisole Liquid S S 316 Tank 25 KL 2 3.0 M X 3.8 M

10 Methyl Anisole Liquid S S 316 Tank 25 KL 1 3.0 M X 3.8 M

11 DCPAE Liquid S S 304 Tank 25 KL 2 3.0 M X 3.8 M

12 2-Cumaronone Liquid S S 304Tank 25 KL 2 3.0 M X 3.8 M

13 Tri Methoxy Toluene Liquid S S 304 Tank 25 KL 2 3.0 M X 3.8 M

14 Methanol Liquid C S Tank 50 KL 1 3..6 M X 5.1M

15 Toluene Liquid C S Tank 50 KL 1 3..6 M X 5.1M

16 Hexane Liquid C S Tank 50 KL 1 3..6 M X 5.1M

17 Ethanol Liquid C S Tank 50 KL 1 3..6 M X 5.1M

18 DMF Liquid MS Tank 20 KL 1 5.3 M X 2.5 M

19 Phenol Molten Drum 200 Kgs 50 -------

20 Methanol Liquid Drum 200 Kgs 13 ------

21 Toluene Liquid Drum 200 Kgs 13 -------

22 Hexane Liquid Drum 200 Kgs 13 -------

23 Ethanol Liquid Drum 200 Kgs 13 -------

24 PEG Liquid Drums 200 Kgs 15 -------

25 4-Chloro Benzoic Acid Liquid Drums 200 Kgs 15 -------

26 Chlorine Gas Tonner 900 Kgs 25 -------

27 Sodium Hydroxide Solid Bags --- -- -------

204

ANNEXURE – IX

SOCIO - ECONOMIC IMPACTS

1) EMPLOYMENT OPPORTUNITIES

The manpower requirement for the proposed project is being expected to generate some

permanent jobs and secondary jobs for the operation and maintenance of plant. This will

increase direct / indirect employment opportunities and ancillary business development to

some extent for the local population.

This phase is expected to create a beneficial impact on the local socio-economic environment.

2) INDUSTRIES

Required raw materials and skilled and unskilled laborers will be utilized maximum from the

local area. The increasing industrial activity will boost the commercial and economical status of

the locality, to some extent.

3) PUBLIC HEALTH

The company regularly examines, inspects and tests its emission from sources to make sure

that the emission is below the permissible limit. Hence, there will not be any significant change

in the status of sanitation and the community health of the area, as sufficient measures have

been taken and proposed under the EMP.

4) TRANSPORTATION AND COMMUNICATION

Since the existing factory is having proper linkage for the transport and communication, the

development of this project will not cause any additional impact.

In brief, as a result of the proposed there will be no adverse impact on sanitation,

communication and community health, as sufficient measures have been proposed to be taken

under the EMP. The proposed scenario is not expected to make any significant change in the

existing status of the socio - economic environment of this region.

205

ANNEXURE-X

______________________________________________________________________________

PROPOSED TERMS OF REFERENCE FOR EIA STUDIES

1. Project Description

• Justification of project.

• Promoters and their back ground

• Project site location along with site map of 5 km area and site details providing various

industries, surface water bodies, forests etc.

• Project cost

• Project location and Plant layout.

• Existing infrastructure facilities

• Water source and utilization including proposed water balance.

• List of Products & their capacity

• Details of manufacturing process of proposed products

• List of hazardous chemicals

• Mass balance of each product

• Storage and Transportation of raw materials and products.

2. Description of the Environment and Baseline Data Collection

• Micrometeorological data for wind speed, direction, temperature, humidity and rainfall in 5

km area.

• Other industries in the impact area

• Prevailing environment quality standards

• Existing environmental status Vis a Vis air, water, noise, soil in 5 km area from the project

site.

• Ground water quality at 5 locations within 5 km.

• Complete water balance

3. Socio Economic Data

• Existing socio-economic status, land use pattern and infrastructure facilities available in the

study area were surveyed.

4. Impacts Identification And Mitigatory Measures

• Identification of impacting activities from the proposed project during construction and

operational phase.

• Impact on air and mitigation measures including green belt

• Impact on water environment and mitigation measures

• Soil pollution source and mitigation measures

• Noise generation and control.

• Solid waste quantification and disposal.

• Control of fugitive emissions

206

5. Environmental Management Plan

• Details of pollution control measures

• Environment management team

• Proposed schedule for environmental monitoring including post project

6. Risk Assessment

• Objectives, Philosophy and methodology of risk assessment

• Details on storage facilities

• Process safety, transportation, fire fighting systems, safety features and emergency

capabilities to be adopted.

• Identification of hazards

• Consequence analysis

• Recommendations on the basis of risk assessment done

• Disaster Management Plan.

7. Information for Control of Fugitive Emissions

8. Information on Rain Water Harvesting

9. Green Belt Development plan

207

ANNEXURE - 11

GIDC PLOT ALLOTMENT LETTER

213

ANNEXURE - 12

WATER SUPPLY LETTER

214

ANNEXURE - 13

EFFLUENT DISCHARGE LETTER

215

ANNEXURE-14

TOPOSHEET

Form - Ienvironmentclearance.nic.in/writereaddata/Online/... · Name of the Project/s BENZO CHEM...

Documents

Transcript of Form - Ienvironmentclearance.nic.in/writereaddata/Online/... · Name of the Project/s BENZO CHEM...