A RAPID TEST FOR FUNGUS THAT CAUSED INJECTION DEATHS IS ANNOUNCED AND

BLOOD-BASED BIOMARKERS MAY LEAD TO EARLIER DIAGNOSIS OF PARKINSON´S

DISEASE

MARIA CAMILA JARAMILLO MONSALVE

MEDCINE STUDENT

INTRODUCTION

Polymerase chain reactionallows amplification of smallDNA fragments

Real time PCR is a useful methodfor the detection andquantification of infectious agents

A RAPID TEST FOR FUNGUS THAT CAUSED INJECTION DEATHS IS

ANNOUNCED

Newswise. January 9 of 2013.Source newsroom: University ofMedicine and Dentistry of NewJersey (UMDNJ)

Marketing of a contaminatedsteroid medication by aninfectious fungus causessome patients deaths.

A RAPID TEST FOR FUNGUS THAT CAUSED INJECTION DEATHS IS ANNOUNCED

The detection of this fungusin biofluids is difficult,because he tends not to befree-floating in the samples.

A RAPID TEST FOR FUNGUS THAT CAUSED INJECTION DEATHS IS ANNOUNCED

The development of asensitive and effective essayallows a rapid detection ofthe fungus in samples.

The essay is very usefulto get an earlydiagnostic.

A RAPID TEST FOR FUNGUS THAT CAUSED INJECTION DEATHS IS ANNOUNCED

A RAPID TEST FOR FUNGUS THAT CAUSED INJECTION DEATHS IS ANNOUNCED

The assay is based on theuse of molecular beacontechnology in real time PCR.

This is a fast methodto detect the fungusand preventconsequences

OBSERVATIONI think that the creation of specificand immediate assay to detect thepresence of the infecting fungus candecrease the consequences of amistake that could cost the lives ofmany people, and provide aneffective way to create anothersimilar methods to detect infectiousdiseases quickly to lower the rates ofmorbimortality

BLOOD-BASED BIOMARKERSMAY LEAD TO EARLIERDIAGNOSIS OF PARKINSON´S

DISEASE

Sok Kean Khoo, David Petillo, UnJung Kang, James H. Resau, BrianBerryhill , Jan Linder, Lars Forsgren,Leslie A. Neuman, Aik ChoonTan. Plasma-Based CirculatingMicroRNA Biomarkers forParkinson's Disease. Journal ofParkinson's Disease, Volume 2/Issue 4(December 2012) DOI: 10.3233/JPD-012144

Science Daily

BLOOD-BASED BIOMARKERS MAY LEAD TO EARLIER DIAGNOSIS OF PARKINSON´S

DISEASE

Parkinson´s disease is aneurodegenerativeprocess.

The differential diagnostic isbased in the evaluation of motorfunctions through a subjectiveclinical rating scales.

BLOOD-BASED BIOMARKERS MAY LEAD TO EARLIER DIAGNOSIS OF PARKINSON´S

DISEASE

The loss of dopaminergicneurons causes motorabnormalities, specific ofParkinson´s disease.

That’s the reason why itsdiagnosis take a lot oftime.

BLOOD-BASED BIOMARKERS MAY LEAD TO EARLIER DIAGNOSIS OF PARKINSON´S

DISEASE

The researchers identifiedand tested the first blood-based circulating microRNAbiomarkers for PD.

OBSERVATION

I think it´s amazing how thesearch for diagnostic methodsmore specific and sensitive, theycan give a pertinent treatmentfor PD patients and this way toprevent motor and cognitiveirreversible consequences.

MEDICAL UTILITY

The new moleculartechniques to detectinfectious agents ordiseases allows an earlydiagnostic.

MEDICAL UTILITY

This methods cananticipate therapeuticinterventions and preventthe fatal consequences.

MEDICAL UTILITY

The detection offungal infections indrugs

An effective way to preventthe sale of contaminatedmedicaments.

MEDICAL UTILITY

Blood-based biomarkers pretendsimproving the PD diagnostic toprevent irreversible loss of motorabilities

[http://www.sciencedaily.com/releases/2013/01/130120145842.htm] checked on Juanary 7th of 2013.”BloodBased Biomarkers May Lead to Earlier Diagnosis ofParkinson's Disease”

[http://www.newswise.com/articles/a-rapid-test-for-fungus-that-caused-injection-deaths-is-announced]checked on January 6th of 2013. “A Rapid Test forFungus That Caused Injection Deaths Is Announced”

Martínez, Lina María; Vargas, Natalia ; Toro, Eduardo;Pamplona, Ana P; Quevedo, Esteban O. “Biologíamolecular”. Ed 7. 2012 . Pp 121

BIBLIOGRAPHY

Felicia Simion