FlexAct® MFfor manifold disposable bags

Benefits can be used at all stages of biopharmaceutical manufacturing processes

Media and buffer processing

Automatic filling of disposable bags with media and buffers for further use in cell culture processes, for example (e.g. Sartorius Cultibag® RM).

Sampling

Automated sampling, e.g. of cell culture processes in pre-defined cycles for quality control purposes.

Transportation and storage

Automated filling of intermediate and final products for storage and shipping. Complete equipment for freezing and thawing disposable bags is available as an option.

The disposable bag manifolds are sterile and ready for immediate use when delivered. Via a single central supply FlexAct® MF automatically fills up to 20 disposable bags in sizes from 50 ml to 5 l with the exact same filling quantity. FlexAct® MF is equally suitable for dis-tributing a large volume of cell culture media, for example, over several bags, as well as for automated multi-sampling for quality control purposes.

Summary of the most important benefits:

– Avoidance of error-prone, manual filling processes

– Avoidance of cross-contamination during filling

– Filling processes traceable at all times

– Fast, safe filling processes

– Automatic results report printout

The system is available as a horizontal version for a maximum of 10 horizontal disposable bags or as a vertical version for a maximum of 20 suspended disposable bags.

Reproducible results accurately documented

FlexAct® MF makes the handling of liquid and biopharmaceutical media even

safer and faster by combining the benefits of disposable bag manifolds with

automatic filling.

High accuracy and reproducibility The measuring system and filling controller are highly precise and deliver reproducible results.

Variable bag attachment Safe guidance of bags from 50 ml to 5 l; Easily accessible connecting tube for welding with a manual welding device.

Pre-definable filling procedures Number of bags, filling weight and filling sequence are individually configurable.

Security User management protects data and configurations against unauthorized or accidental changes.

Flow rate monitoring Filling stops automatically if the media supply is interrupted.

Automatic batch report Documentation of the filling results with printout on labels for each bag and report for all bags.

Easy to clean Easily accessible surfaces; even the smallest corners are easy to clean.

Your benefits

Equipment Supplied

FlexAct® MF is available as a horizontal version for a maximum of 10 horizontal dispos-able bags or as a vertical version for a maximum of 20 suspended disposable bags.

The supplied equipment includes:

– Valve column with electrical control units

– Control outputs for valves to control filling (coarse and fine flow)

– Pinch valve before every bag

– Sensor to determine the liquid level in the tubing line

– Removable frame with 10 shelves or 10 (20) hooks for hanging the bags

– Precision weighing system

– Combics Pro controller with manifold filling software

– Matrix printer for the batch report

– Thermal transfer printer for bag labels

Combics Pro

Matrix printer YDP10-0CE and thermal transfer printer YDP14IS-0CEUVTH

Horizontal Vertical