First-in-Human Testing of a Wirelessly Controlled Drug Delivery Microchip by Robert Farra, Norman...
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First-in-Human Testing of a Wirelessly Controlled Drug Delivery Microchip
by Robert Farra, Norman F. Sheppard, Laura McCabe, Robert M. Neer, James M. Anderson, John T. Santini, Michael J. Cima, and Robert Langer
Sci Transl MedVolume 4(122):122ra21-122ra21
February 22, 2012
Published by AAAS
![Page 2: First-in-Human Testing of a Wirelessly Controlled Drug Delivery Microchip by Robert Farra, Norman F.…](https://reader035.fdocuments.in/reader035/viewer/2022070615/5a4d1bc97f8b9ab0599d6331/html5/thumbnails/2.jpg)
Fig. 1 The microchip-based drug delivery device and overview of study design.
Robert Farra et al., Sci Transl Med 2012;4:122ra21
Published by AAAS
![Page 3: First-in-Human Testing of a Wirelessly Controlled Drug Delivery Microchip by Robert Farra, Norman F.…](https://reader035.fdocuments.in/reader035/viewer/2022070615/5a4d1bc97f8b9ab0599d6331/html5/thumbnails/3.jpg)
Fig. 2 PK dosing results.
Robert Farra et al., Sci Transl Med 2012;4:122ra21
Published by AAAS
![Page 4: First-in-Human Testing of a Wirelessly Controlled Drug Delivery Microchip by Robert Farra, Norman F.…](https://reader035.fdocuments.in/reader035/viewer/2022070615/5a4d1bc97f8b9ab0599d6331/html5/thumbnails/4.jpg)
Fig. 3 Bone marker and calcium measurements.
Robert Farra et al., Sci Transl Med 2012;4:122ra21
Published by AAAS
![Page 5: First-in-Human Testing of a Wirelessly Controlled Drug Delivery Microchip by Robert Farra, Norman F.…](https://reader035.fdocuments.in/reader035/viewer/2022070615/5a4d1bc97f8b9ab0599d6331/html5/thumbnails/5.jpg)
Fig. 4 Tissue histology results from a representative patient, MC-0012.
Robert Farra et al., Sci Transl Med 2012;4:122ra21
Published by AAAS