The Lennox-Lombroso Pediatric Epilepsy Conference

February 2-3, 2018Hilton Boston Back Bay | Boston, MA

REGISTER NOW | bostonchildrens.org/epilepsy2018

Early bird registration rates expire 11/30/17

A History of Innovation & Quality Care

Boston Children’s Hospital has been at the forefront of pediatric epilepsy research and care since the founding of the first comprehensive pediatric epilepsy treatment unit in 1944 by Dr. William Lennox.

In 1962, Dr. Cesare Lombroso succeeded Dr. Lennox as Chief of the Seizure Unit and EEG Laboratory at Boston Children’s, a position he held until 1988. Both of these physicians believed that the best results in children with seizures are achieved in a center that simultaneously addresses the medical, psychosocial, behavioral and family issues that impact their lives. With this focus, the Seizure Unit at Boston Children’s Hospital grew to be a preeminent center for both treatment and clinical investigation.

State-of-the-art Education: The Lennox-Lombroso Pediatric Epilepsy Conference

The inaugural Lennox-Lombroso Pediatric Epilepsy Conference extends Boston Children’s tradition of excellence in continuing medical education to the field of childhood epilepsy diagnosis, management, and research. The course will cover a variety of topics including medical advances, discoveries and innovative technological approaches in epilepsy genetics, neurocritical care, computational neurophysiology, surgical procedures, and EEG ontogeny.

In addition to presenting the latest advances and innovations in epilepsy research and care, the course will provide the practitioner with clear guides in terms of how to apply knowledge in all domains of pediatric epilepsy. Core faculty are from the Division of Epilepsy and Clinical Neurophysiology at Boston Children’s Hospital and invited faculty have been selected to highlight and honor faculty alumni who continue to make great contributions to the field, including Keynote Speakers Gregory L. Holmes MD, successor to Dr. Lombroso and current Chair of Neuroscience at the University of Vermont; Mohamad Mikati MD, Chief of Pediatric Neurology at Duke University; and James J. Riviello, Jr. MD, Professor of Pediatric Neurology and Developmental Neuroscience at Baylor College of Medicine.

Target audience This course is designed to meet the educational needs of physicians, clinician-scientists, physician assistants, nurses, nurse practitioners, psychologists, allied health professionals, residents and fellows who specialize or have an interest in:

› pediatric neurology

› pediatric epileptology

› epilepsy and clinical neurophysiology

› neuropsychology

› primary care

* This course is also open to any patients and families that wish to attend.

Registration fees

Physician early bird fee* $500

Physician (regular rate) $550

Allied Health Professionals $300

Trainee $300

*Early bird ends 11/30/2017

Course directors

» Phillip L. Pearl, MD

» Arnold J. Sansevere, MD

Learning objectives Upon completion of this course, participants will be able to:

› recognize the effects of seizures and spikes on the developing brain

› identify high risk populations for seizures in the critical care unit and apply standardized EEG interpretation

› select patients for epilepsy surgery including the rationale for different forms of invasive monitoring and technical approaches

› identify the correct genetic test and translational opportunity for selected patients depending upon the clinical presentation

Accreditation In support of improving patient care, Boston Children’s Hospital is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

Physicians Boston Children’s Hospital designates this live activity for a maximum of 14.75 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in this activity.

AAPA accepts AMA category 1 credit for the PRA from organizations accredited by ACCME.

Nurses Boston Children’s Hospital designates this activity for 14.75 contact hours for nurses. Nurses should claim only the credit commensurate with the extent of their participation in the activity.

Refund policy

To register by credit card, please visit bostonchildrens.org/epilepsy2018. To register by check, please contact the CME Department at: cmedepartment@childrens.harvard.edu to discuss payment. Please make checks payable to Boston Children’s Hospital. Telephone or fax registration is not accepted. Registration with cash payment is not permitted. Upon receipt of your paid registration, an email confirmation from the Boston Children’s office will be sent to you. Be sure to include an email address that you check frequently. Your email address is used for critical information, including registration confirmation, evaluation and certificate.

Fifty-percent (50%) refunds will be issued for all cancellations received prior to the start of the course. Refund requests must be received by postal mail, email or telephone. “No shows” are subject to the full course fee, and no refunds will be issued once the conference has started.

Disclosure policy

Boston Children’s Hospital adheres to all ACCME Essential Areas, Standards, and Policies. It is Boston Children’s policy that those who have influenced the content of a CME activity (e.g. planners, faculty, authors, reviewers and others) disclose all relevant financial relationships with commercial entities so that Boston Children’s may identify and resolve any conflicts of interest prior to the activity. These disclosures will be provided in the activity materials along with disclosure of any commercial support received for the activity. Additionally, faculty members have been instructed to disclose any limitations of data and unlabeled or investigational uses of products during their presentations.

Inquiries

cmedepartment@childrens.harvard.edu or at 617-919-3108.

About the course

Schedule, Day 1: Friday, Feb. 2, 2018

SYMPOSIUM: EPILEPSY GENETICS (8–11:15 a.m.)

7–7:45 a.m. Breakfast

7:45–8 a.m. Announcements/Administration

8–8:45 a.m. KEYNOTE Emerging Treatments of Epileptic Encephalopathy Mohamad A. Mikati, MD

8:45–9:15 a.m. Case-based Testing in the New Genomic Era Christelle Achkar, MD

9:15–9:45 a.m. Case-based Epilepsy Genetics in the 21st Century Heather Olson, MD, MS

9:45–10:15 a.m. Epilepsy Genetics: From Zebrafish to Clinic Annapurna Poduri, MD, MPH

10:15–10:45 a.m. BREAK

10:45–11:15 a.m. PANEL Q&A

11:15 a.m.–noon Neuro-Modulation–A New Era in Epilepsy Research and Treatment Alexander Rotenberg, MD, PhD

Noon–1:15 p.m. LUNCH

1:15–1:45 p.m. Neonatal Seizures Ann M. Bergin, MB, ScM, MRCP

SYMPOSIUM: INFANTILE SPASMS (1:45–2:45 p.m.)

1:45–2:15 p.m. Clinical Chellamani Harini, MD

2:15–2:45 p.m. Experimental Christopher J. Yuskaitis, MD, PhD

2:45–3:15 p.m. BREAK

3:15–3:45 p.m. Spikes, Seizures and Cognition Katrina Boyer, PhD

SYMPOSIUM: SURGERY, PART 2 (3:45–4:45 p.m.)

3:45–4:15 p.m. Intracranial Monitoring: Pediatric Stereo EEG Joseph Madsen, MD

4:15–4:45 p.m. Computer-based Techniques to Improve Epilepsy Surgery Joseph Madsen, MD

4:45–5 p.m. Conclusions and Future Directions Phillip L. Pearl, MD

*Program changes/substitutions may be made without notice.

Schedule, Day 2: Saturday, Feb. 3, 2018

7–7:45 a.m. Breakfast

7:45–8 a.m. Announcements/Administration

8–8:30 a.m. Welcome and Historical Overview Presenter: Phillip L. Pearl, MD Guests of Honor: Paul J. Lombroso, MD & Jane Lennox Herner

8:30–9:30 a.m. KEYNOTE Seizures, Spikes, and Brain Development Gregory L. Holmes, MD

SYMPOSIUM: CRITICAL CARE IN EPILEPSY (9:30–11:45 a.m.)

9:30–10:15 a.m. KEYNOTE Critical Care and Epilepsy: Past, Present and Future James J. Riviello Jr., MD

10:15–10:45 a.m. Status Epilepticus Tobias Loddenkemper, MD

10:45–11 a.m. BREAK

11–11:30 a.m. ICU EEG Cases: Rules of the Road Arnold J. Sansevere, MD

11:30–11:45 a.m. PANEL Q&A

11:45 a.m.–12:15 p.m. Computational Neurophysiology Jurriaan M. Peters, MD, PhD

12:15–1:30 p.m. LUNCH

1:30–2 p.m. EEG: Clinical Cases Mark H. Libenson, MD

2–2:30 p.m. Case Studies of Epilepsy, Cognition and Memory Clemente Vega, PsyD, ABPP-CN

SYMPOSIUM: SURGERY, PART 1 (2:30–5 p.m.)

2:30–3 p.m. Neurological Outcomes After Epilepsy Surgery: The BCH Database Jeffrey Bolton, MD

3–3:30 p.m. Electrocorticographic Applications Masanori Takeoka, MD

3:30–4 p.m. BREAK

4–5 p.m. Surgical Cases: The Best of... Epilepsy Fellows and Faculty

5–6 p.m. Creativity and the Brain... at the Piano Phillip L. Pearl, MD

6–8 p.m. DINNER/RECEPTION Living a Life with Epilepsy and Remembrances of Dr. Lombroso Joan McGann

GUESTS OF HONOR

Paul Lombroso, MDSon of Cesare T. Lombroso, MD, PhDElizabeth Mears and House Jameson Professor in the Child Study Center and Professor of Neuroscience and of Psychiatry; Director, Laboratory of Molecular Neurobiology; Biological and Biomedical Sciences, Yale University

Jane Lennox HernerGranddaughter of William Gordon Lennox, MD

COURSE DIRECTORS

Phillip L. Pearl, MDWilliam G. Lennox Chair and Professor of Neurology, Harvard Medical School; Director of Epilepsy and Clinical Neurophysiology, Boston Children’s Hospital

Arnold J. Sansevere, MDInstructor in Neurology, Harvard Medical School; Assistant in Neurology, Boston Children’s Hospital

SPEAKERS

Christelle Achkar, MD Instructor in Neurology, Harvard Medical School; Assistant in Neurology, Boston Children’s Hospital

Ann M. Bergin, MB, ScM, MRCP Assistant Professor of Neurology, Harvard Medical School; Vice President, Medical Staff Organization, Assistant in Neurology, Director, Multidisciplinary Ketogenic Diet Program, Boston Children’s Hospital

Jeffrey Bolton, MDInstructor in Neurology, Harvard Medical School; Assistant in Neurology, Boston Children’s Hospital

Katrina Boyer, PhD Instructor in Psychology, Department of Psychiatry, Harvard Medical School; Neuropsychologist, Director, Neuropsychology of Epilepsy Program, Boston Children’s Hospital

Chellamani Harini, MD Instructor in Neurology, Harvard Medical School; Assistant in Neurology, Epilepsy Program, Boston Children’s Hospital

Gregory L. Holmes, MDKeynote Speaker | Chair, Department of Neurological Sciences, Professor of Neurological Sciences and Pediatrics, Larner College of Medicine, University of Vermont

Mark H. Libenson, MDAssistant Professor of Neurology, Harvard Medical School; Senior Associate in Neurology; Director, EEG Laboratory; Medical Director, Electroneurodiagnostic (END) Technology Program, Boston Children’s Hospital

Tobias Loddenkemper, MDAssociate Professor of Neurology, Harvard Medical School; Associate in Neurology, Electroneurodiagnostic (END) Technology Program; Director, Clinical Epilepsy Research Program, Boston Children’s Hospital Program, Boston Children’s Hospital

Joseph Madsen, MD Associate Professor of Neurosurgery, Harvard Medical School; Associate in Neurosurgery, Director, Epilepsy Surgery Program, Boston Children’s Hospital

Mohamad A. Mikati, MDKeynote Speaker | Wilburt C. Davison Professor of Pediatrics, Professor of Neurobiology, Chief, Division of Pediatric Neurology, Director, Pediatric Epilepsy Program, Duke University School of Medicine

Heather Olson, MD, MS Instructor in Neurology, Harvard Medical School; Assistant in Neurology, Boston Children’s Hospital

Jurriaan M. Peters, MD, PhD Assistant Professor of Neurology, Harvard Medical School; Assistant in Neurology, Boston Children’s Hospital

Annapurna Poduri, MD, MPH Associate Professor of Neurology, Harvard Medical School; Director, Epilepsy Genetics Program, Associate in Neurology, Boston Children’s Hospital

James J. Riviello Jr., MDKeynote Speaker | Professor, Pediatric Neurology and Developmental Neuroscience, Baylor College of Medicine; Associate Section Head for Epilepsy, Neurophysiology, and Neurocritical Care, Section of Neurology and Developmental Neuroscience, Texas Children’s Hospital

Alexander Rotenberg, MD, PhD Associate Professor of Neurology, Harvard Medical School; Associate in Neurology, Director, Neuromodulation Program, Boston Children’s Hospital

Scellig Stone, MD, PhD, FRCSC Assistant Professor of Neurology, Harvard Medical School; Associate in Neurosurgery; Director, Movement Disorders and Deep Brain Stimulation Program, Boston Children’s Hospital

Masanori Takeoka, MD

Assistant Professor of Neurology, Harvard Medical School; Assistant in Neurology, Co-Director, Sturge-Weber Syndrome Clinic, Boston Children’s Hospital

Clemente Vega, PsyD, ABPP-CN IInstructor in Psychology, Department of Psychiatry, Harvard Medical School; Staff Neuropsychologist, Boston Children’s Hospital

Christopher J. Yuskaitis, MD, PhD Instructor in Neurology, Harvard Medical School; Assistant in Neurology, Boston Children’s Hospital

Faculty

Continuing Medical Education Department

300 Longwood Avenue, LM 7, Boston, MA 02115

February 2–3, 2018 Hilton Boston Back Bay

REGISTER NOW | bostonchildrens.org/epilepsy2018

The Lennox-Lombroso Pediatric Epilepsy Conference

Early bird registration rates expire 11/30/17