Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program...

69
#Rx Summit www.NationalRxDrugAbuseSummit.org Faster Data: The CDC-Funded Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease Control and Prevention (CDC) Alana Vivolo-Kantor, PhD, MPH, Behavioral Scientist, CDC Julie O'Donnell, PhD, MPH, Epidemiologist, CDC Federal Track Moderator: Puja Seth

Transcript of Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program...

Page 1: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosures

Puja Seth PhD Alana Vivolo-Kantor PhD MPH and Julie ODonnell PhD MPH have disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce healthcare goods and services

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosures

All plannersmanagers hereby state that they or their spouselife partner do not have any financial relationships or relationships to products or devices with any commercial interest related to the content of this activity of any amount during the past 12 months

The following plannersmanagers have the following to disclose- Kelly J Clark MD MBA FASAM DFAPA ndash

Consulting fees Braeburn Indivior

Rx Summit wwwNationalRxDrugAbuseSummitorg

Learning Objectives

Describe the process to develop CDC and state case definitions

Identify patterns of recent nonfatal heroin and opioid drug overdoses across 12 states

Identify drugs involved in deaths and circumstances precipitating the deaths based on data

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)

Puja Seth PhDAlana Vivolo-Kantor PhD

Julie OrsquoDonnell PhD

Division of Unintentional Injury PreventionCenters for Disease Control and Prevention

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Puja Seth PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Goals

Describe CDCrsquos new opioid overdose surveillance program Discuss how rapidly available data can be used to inform

overdose response and prevention efforts Overview of emergency department and emergency medical

services data for use in tracking opioid overdose trends Describe the development of case definitions for opioid and

heroin overdose in emergency department and emergency medical services data

Overview of data available for fatal opioid overdoses and associated risk factors and its use in informing prevention and response recommendations

Rx Summit wwwNationalRxDrugAbuseSummitorg

Opioid Overdoses Treated in Emergency Departments

Vivolo-Kantor AM Seth P Gladden RM Mattson CL Baldwin GT Kite-Powell A Coletta MA Vital Signs Trends in Emergency Department Visits for Suspected Opioid Overdoses mdash United States July 2016ndashSeptember 2017(httpswwwcdcgovmmwrvolumes67wrmm6709e1htm) MMWR Morb Mortal Wkly Rep201867

Rx Summit wwwNationalRxDrugAbuseSummitorg

Vivolo-Kantor AM Seth P Gladden RM Mattson CL Baldwin GT Kite-Powell A Coletta MA Vital Signs Trends in Emergency Department Visits for Suspected Opioid Overdoses mdash United States July 2016ndashSeptember 2017(httpswwwcdcgovmmwrvolumes67wrmm6709e1htm) MMWR Morb Mortal Wkly Rep201867

Rx Summit wwwNationalRxDrugAbuseSummitorg

2000 Rapid Increase in Drug Overdose Death Rates by County

SOURCE NCHS Data Visualization Gallery

Rx Summit wwwNationalRxDrugAbuseSummitorgSOURCE NCHS Data Visualization Gallery

2005 Rapid Increase in Drug Overdose Death Rates by County

Rx Summit wwwNationalRxDrugAbuseSummitorgSOURCE NCHS Data Visualization Gallery

2010 Rapid Increase in Drug Overdose Death Rates by County

Rx Summit wwwNationalRxDrugAbuseSummitorgSOURCE NCHS Data Visualization Gallery

2016 Rapid Increase in Drug Overdose Death Rates by County

Rx Summit wwwNationalRxDrugAbuseSummitorg

RISE IN OPIOID DEATHS

Overlapping Entangled but Distinct Epidemics

Natural and semi-synthetic opioidslike oxycodone or hydrocodone

Methadone

Heroin

SOURCE National Vital Statistics System Mortality File

Dea

ths

per 1

000

00 p

opul

atio

n

Chart1

Synthetic opioidslike fentanyl
3 Waves
Almost 351630 people have died from an opioid overdose during 1999-2016
Natural and semi-synthetic opioid analgesic
Methadone
Synthetic opioid analgesic excluding methadone
Heroin
1
03
03
07
12
05
03
06
17
1
05
07
19
15
06
07
27
18
07
08
31
15
1
11
37
14
08
14
35
11
1
27
39
1
31
41

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

CDCrsquos Pillars on Opioids Conducting surveillance and research

Building state local and tribal prevention efforts

Supporting healthcare providers and health systems

Partnering with public safety officials

Encouraging consumers to make safe choices about opioids raising awareness about prescription opioid misuse and overdose

Rx Summit wwwNationalRxDrugAbuseSummitorg

Enhanced State Opioid Overdose Surveillance (ESOOS) 12 states funded in September 2016 20 additional states and the

District of Columbia funded in September 2017 (through September 2019)

Strategy One Increase timeliness of non-fatal opioid overdose reporting- Use syndromic surveillance to establish an early warning system to

detect sharp increases or decreases in non-fatal opioid overdoses - Three indicators suspected all-drug opioid and heroin

Alaska California Connecticut Delaware DC Florida Georgia Illinois Indiana Kentucky Louisiana Maine Maryland Massachusetts Michigan Minnesota Missouri Nevada New Hampshire New Jersey New Mexico North Carolina Ohio Oklahoma Pennsylvania Rhode Island Tennessee Utah Vermont Virginia Washington West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

Enhanced State Opioid Overdose Surveillance (ESOOS) Strategy Two Increase timeliness of fatal opioid overdose

reporting- Capture detailed information on toxicology death scene

investigations and other risk factors that may be associated with a fatal overdose

Strategy Three widespread dissemination- Rapidly disseminate surveillance findings to key stakeholders

working to prevent or respond to opioid overdoses

ESOOS program expansion in September 2017- At least 60 for comprehensive toxicology testing for opioid-

involved deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

Funded ESOOS states

Rx Summit wwwNationalRxDrugAbuseSummitorg

Enhanced State Opioid Overdose Surveillance (ESOOS)

Nonfatal Opioid Overdoses Reported

Quarterly

Emergency Department Visits EMS Transports

Fatal Opioid Overdoses Reported within 8 months

of death

Death CertificatesMEC reports

Toxicology reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

Next Two Presentationshellip

The Utilization of Emergency Department Syndromic Surveillance and Emergency Medical Services Data to Monitor Nonfatal Opioid Overdoses ndash Dr Alana Vivolo-Kantor

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System ndash Dr Julie OrsquoDonnell

Rx Summit wwwNationalRxDrugAbuseSummitorg

The utilization of emergency department syndromic surveillance

and emergency medical services data to monitor nonfatal opioid

overdosesPresenter Alana Vivolo-Kantor PhD

Behavioral ScientistCenters for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Julie OrsquoDonnell R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Alana Vivolo-Kantor PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Why Emergency Department and Emergency Medical Service Data for Surveillance

Need- Identify areas experiencing rapid increases in opioid overdoses to

inform responses- More quickly identify promising practices to reduce opioid overdoses

Proven utility to public health and scalable- Local jurisdictions already using it to track and respond to drug

overdoses- Findings from Epi-Aid investigations and collaborative work with states- Leverage existing state and national resources (BioSenseESSENCE)

Action at local and national level- Track quarterly trends across the nation to inform national policy- Improve more rapid local and state public health response

Rx Summit wwwNationalRxDrugAbuseSummitorg

Our Philosophy

Focus on detecting change- Pushing system by looking at trend data over quarters- Some jurisdictions may be able to get and report preliminary

burden estimates

Jurisdiction-driven definitions will outperform national definitions- Local flexibility enhances quality and utility by accounting for large

variance in text entries and coding

National guidance- National definition will provide a good starting place- Guidance to encourage common conceptual definition (eg no

withdrawaldetox) and learn from previous work

Rx Summit wwwNationalRxDrugAbuseSummitorg

Our approach

Non-fatal overdoses

Emergency Department

Near real-time ED collection (ie

syndromic ESSENCE)

Case-level or aggregate data shared

through ESSENCE (BioSense) or directly

with CDC

DischargeBilling Data

Case-level or aggregate data shared

directly with CDC

Emergency Medical Services

Case-level or aggregate data shared

directly with CDC

Includes breakdown by

sex age group and county of residence

Raceethnicity is optional

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency Department Data

Two sources- Near real-time syndromic data (visit information within 24-48 hours)- Lagged hospital billing or claims data (usually within 3-4 weeks)

Different variables used- Discharge diagnosis codes (eg ICD-10-CM) ndash available in billing

data and sometimes in syndromic- Free text fields (eg chief complaint provided by Doctor) ndash

available only in syndromic

Rx Summit wwwNationalRxDrugAbuseSummitorg

Case definitions for suspected overdose

If syndromic- Uses both discharge codes (ie ICD-9-CM ICD-10-CM and

SNOMED) and free text fields such as chief complaint or triage notes

- Free text searches use common terms slang and misspellings (eg herion instead of heroin)

If hospital billing or claimshellip- Uses only discharge codes (ie ICD-9-CM ICD-10-CM and

SNOMED)

Discharge codes use are for acute unintentional or undetermined drug poisoning (eg T401X1A in ICD-10-CM) and may also include some substance useabuse codes (ie F11 in ICD-10-CM)

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency medical services data

Capture potential EMS transports to EDs- Excludes instances where individual is pronounced deceased on

the scene inter-facility transports and when EMTs provide no ldquotreatmentrdquo (eg patient refused or required no treatment or transport)

Different variables used- Chief Complaint Secondary complaint- Narrative- Provider Impression- ICD-1O-CM codes- Medication administered (ie Naloxone)- Response to medication administered (ie awake following

Naloxone administration)

Rx Summit wwwNationalRxDrugAbuseSummitorg

Challenges in EMS data

Transition to newer versions of NEMSIS- Some states working in up to three versions (v221 v334 amp

v340)

Different case definitions in different versions

Missing data feeds

Not all EMS agencies share data

Varying time frame in when data is received- lt24 hours to 6 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Data submission process

Rx Summit wwwNationalRxDrugAbuseSummitorg

Sample quality control report

ObsSTATE YEAR QUARTER ERROR_TEXTTOTAL ED VISITS (GENDER)

TOTAL ED VISITS (AGE)

1XX 2017 1 ED Visits mismatch 98287 98309

2XX 2017 2 ED Visits mismatch 98195 98230

3XX 2017 3 ED Visits mismatch 99167 99205

Rx Summit wwwNationalRxDrugAbuseSummitorg

Sample site report

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results All drug (11 sites)

0

10

20

30

40

50

60

70

80

90

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d al

l dru

g ov

erdo

se ra

tes

by

100

00 E

D v

isits

Quarter year

-2000

-1000

000

1000

2000

3000

4000

5000

6000

7000

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Opioid (11 sites)

0

5

10

15

20

25

30

35

40

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Heroin (11 sites)

0

5

10

15

20

25

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-15

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

Annual percentage changes (11 sites)

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Chart1

All drug
Heroin
Opioid
889150252325
302341597796
208009807928
1075831326045
476222826087
283004552352
167997701832
215786123488
271305063812

table with overall

table with overall

All drug
Suspected all drug overdose rates by 10000 ED visits

Sheet1

All drug

table by sex

Opioid
Quarter year
Suspected opioid overdose rates by 10000 ED visits

table by age

Opioid

table by state

Heroin
Quarter year
Suspected opioid overdose rates by 10000 ED visits
Heroin
All drug
Heroin
Opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Summary

Stable increases for all drug and heroin from Q1 2016 to Q3 2017- Opioid had stable increases from Q3 2016 to Q2 2017

Moderate decreases from Q2 to Q3 2017- 9 for all drug 9 for opioid and 12 for heroin

Annual percentage changes were above 15 increases- Q1 to Q1 89 all drug 30 heroin amp 21 opioid- Q2 to Q2 108 all drug 48 heroin amp 28 opioid- Q3 to Q3 17 all drug 22 heroin amp 27 opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency department data dissemination efforts

ldquoOpioid Overdoses Treated in Emergency Departmentsrdquo -httpswwwcdcgovvitalsignsopioid-overdosesindexhtml

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose

Reporting System

Presenter Julie OrsquoDonnell PhD MPHEpidemiologist

Centers for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Alana Vivolo-Kantor R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Julie OrsquoDonnell PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Increase in deaths outpaces increase in use

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid

overdose

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid overdose surveillance

Track specific substances contributing to overdose deaths

Detect newly-emerging substances involved in overdose

Determine risk factors circumstances associated with fatal overdose

Assess common drug combinations Provide more timely data on overdose deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

State Unintentional Drug Overdose Reporting System (SUDORS)

Death certificates

Medical examiner

coroner reportsToxicology

reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data submitted bi-annually

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

1 Data entry started

2 Data entry finished

1 Data entry started

2 Data entry finished

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS leverages National Violent Death Reporting System (NVDRS) platform

- Basic descriptors- Compare across demographics

- Recent release from institution- Overdose location - Survival time

- Mental health diagnoses- Substance abuse treatment history

- Substances present- Substances contributing to death

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Maine 1941 -1273 225 278 1523 -201 3951 -692 257 -813 2945 981 793 656 -299 -2255 3199 2197
Massachusetts na na na na na na 1561 -157 -848 -1148 311 1897 553 -31 -13 -1632 456 2146
New Hampshire 511 1514 -1438 -832 2583 -961 318 64 -433 -1791 2967 -876 825 -184 -1002 -2016 3363 -17
Pennsylvania na na 869 -102 1211 -116 na na 2979 1751 2589 -594 na na 2601 1534 2735 -735
Rhode Island na na 735 -790 1002 -1594 na na 28 454 544 -1191 na na 121 1057 566 -3262
West Virginia -1596 875 2978 -1543 409 -1651 -367 995 4331 -1664 402 -2377 -769 1847 4571 -1584 -199 -3022
Kentucky -102 1242 -1707 2211 1092 -1468 1095 5192 -2694 4045 352 -2002 -043 5541 -3206 5012 -408 -1624
New Mexico 2932 283 521 -078 445 -716 255 -1298 2611 151 -501 -1093 -487 -3061 3227 987 -1715 323
Missouri 068 -304 754 028 114 421 292 827 477 -177 954 767 -046 1839 096 -512 966 125
Ohio na na 107 1216 1596 -1865 na na 2274 2567 2167 -3194 na na 2182 2254 2086 -3348
Wisconsin -229 1388 861 2928 888 931 -948 986 1712 6728 322 314 -1457 91 983 9621 196 668
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 1514 2112 1966 2017 1853 2398 2634
Massachusetts 7036 8133 8006 7327 6486 6687 7956
New Hampshire 3806 3927 4179 3998 3282 4255 3882
Pennsylvania na na 1265 1641 1929 2428 2284
Rhode Island na na 1498 154 161 1698 1496
West Virginia 2258 2176 2392 3428 2857 2972 2266
Kentucky 2095 2325 3532 258 3624 3752 3001
New Mexico 1927 1976 1719 2168 2201 2091 1862
Missouri 1472 1515 1641 1719 1688 185 1991
Ohio na na 236 2897 3641 443 3015
Wisconsin 664 601 66 773 1294 1336 1377
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 502 9 959 931 721 952 1161
Massachusetts 4035 4258 4126 359 3004 3141 3815
New Hampshire 2514 2721 2671 2403 1919 2564 2128
Pennsylvania na na 1013 1277 1473 1876 1738
Rhode Island na na 803 812 898 949 639
West Virginia 1496 1381 1636 2384 2006 1966 1372
Kentucky 1772 1764 2741 1863 2796 2682 2247
New Mexico 902 858 595 787 865 717 74
Missouri 1002 997 118 1192 1131 124 1255
Ohio na na 1804 2198 2693 3254 2165
Wisconsin 286 244 267 293 575 586 625
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 5609 6697 5845 5976 6142 7078 6936
Massachusetts na na na na na na na
New Hampshire 5678 5968 6872 5883 5394 6787 6135
Pennsylvania na na 8374 9102 9010 10100 9983
Rhode Island na na 3567 3829 3527 3880 3262
West Virginia 4628 3889 4229 5489 4642 4832 4034
Kentucky 6756 6687 7517 6234 7613 8444 7205
New Mexico 5291 6842 7036 7402 7345 7672 7123
Missouri 3213 3235 3137 3373 3383 3421 3565
Ohio na na 8696 8789 9859 11432 9300
Wisconsin 2724 2661 3031 3291 4255 4633 5064
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
15 to 24
25 to 34
35 to 54
55 and up
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Male -140 7355 827 901 1286 -927 742 -758 1157 1241 1306 -829 146 301 1082 1242 1306 -1249
Female 841 5151 103 733 1257 -1521 659 -922 533 1204 1494 -1014 -132 1299 229 1331 1617 -1214
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 4888 4820 8365 9057 9873 11142 10110
Female 3201 3470 5257 5312 5701 6418 5442
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 3611 3879 3585 40 4496 5083 4662
Female 159 1695 1538 162 1816 2087 1875
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 2295 2328 2399 2658 2988 3379 2957
Female 839 828 936 957 1085 126 1107
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017 q1 q2 q3
All drug 3948 4061 6589 6894 7458 8430 7696 889150252325 1075831326045 167997701832
Heroin 1452 1472 1571 1681 1891 2173 191 302341597796 476222826087 215786123488
Opioid 2447 2636 2429 2636 2956 3382 3088 208009807928 283004552352 271305063812
Q12016-Q12017 Q22016-Q22017 Q32016-Q32017
All drug 889150252325 1075831326045 167997701832
Heroin 302341597796 476222826087 215786123488
Opioid 208009807928 283004552352 271305063812
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Heroin 136 674 701 1251 1486 -1209
Opioid 77 -785 853 1212 1442 -868
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Heroin 1452 1472 1571 1681 1891 2173 191
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Heroin 1452 1472 1571 1681 1891 2173 191
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Opioid 77 -785 853 1212 1442 -868
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Heroin 136 674 701 1251 1486 -1209
Q12016-Q12017 Q12016-Q12017 Q12016-Q12017
Q22016-Q22017 Q22016-Q22017 Q22016-Q22017
Q32016-Q32017 Q32016-Q32017 Q32016-Q32017
Column1 Any opioid Natural and semi-synthetic opioid analgesic Methadone Synthetic opioid analgesic excluding methadone Heroin
1999 1 03 03 07
21 1 04 03 07
2001 24 12 05 03 06
32 15 08 04 07
2003 35 17 1 05 07
39 18 13 06 06
2005 43 19 15 06 07
51 23 18 09 07
2007 54 27 18 07 08
57 3 16 08 1
2009 59 31 15 1 11
62 35 15 1 1
2011 66 37 14 08 14
67 35 12 08 19
2013 74 35 11 1 27
86 38 11 18 34
2015 104 39 1 31 41
133 44 1 62 49
1999 1999 1999 1999
1 04 03 07
2001 2001 2001 2001
15 08 04 07
2003 2003 2003 2003
18 13 06 06
2005 2005 2005 2005
23 18 09 07
2007 2007 2007 2007
3 16 08 1
2009 2009 2009 2009
35 15 1 1
2011 2011 2011 2011
35 12 08 19
2013 2013 2013 2013
38 11 18 34
2015 2015 2015 2015
44 1 62 49
Page 2: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosures

Puja Seth PhD Alana Vivolo-Kantor PhD MPH and Julie ODonnell PhD MPH have disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce healthcare goods and services

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosures

All plannersmanagers hereby state that they or their spouselife partner do not have any financial relationships or relationships to products or devices with any commercial interest related to the content of this activity of any amount during the past 12 months

The following plannersmanagers have the following to disclose- Kelly J Clark MD MBA FASAM DFAPA ndash

Consulting fees Braeburn Indivior

Rx Summit wwwNationalRxDrugAbuseSummitorg

Learning Objectives

Describe the process to develop CDC and state case definitions

Identify patterns of recent nonfatal heroin and opioid drug overdoses across 12 states

Identify drugs involved in deaths and circumstances precipitating the deaths based on data

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)

Puja Seth PhDAlana Vivolo-Kantor PhD

Julie OrsquoDonnell PhD

Division of Unintentional Injury PreventionCenters for Disease Control and Prevention

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Puja Seth PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Goals

Describe CDCrsquos new opioid overdose surveillance program Discuss how rapidly available data can be used to inform

overdose response and prevention efforts Overview of emergency department and emergency medical

services data for use in tracking opioid overdose trends Describe the development of case definitions for opioid and

heroin overdose in emergency department and emergency medical services data

Overview of data available for fatal opioid overdoses and associated risk factors and its use in informing prevention and response recommendations

Rx Summit wwwNationalRxDrugAbuseSummitorg

Opioid Overdoses Treated in Emergency Departments

Vivolo-Kantor AM Seth P Gladden RM Mattson CL Baldwin GT Kite-Powell A Coletta MA Vital Signs Trends in Emergency Department Visits for Suspected Opioid Overdoses mdash United States July 2016ndashSeptember 2017(httpswwwcdcgovmmwrvolumes67wrmm6709e1htm) MMWR Morb Mortal Wkly Rep201867

Rx Summit wwwNationalRxDrugAbuseSummitorg

Vivolo-Kantor AM Seth P Gladden RM Mattson CL Baldwin GT Kite-Powell A Coletta MA Vital Signs Trends in Emergency Department Visits for Suspected Opioid Overdoses mdash United States July 2016ndashSeptember 2017(httpswwwcdcgovmmwrvolumes67wrmm6709e1htm) MMWR Morb Mortal Wkly Rep201867

Rx Summit wwwNationalRxDrugAbuseSummitorg

2000 Rapid Increase in Drug Overdose Death Rates by County

SOURCE NCHS Data Visualization Gallery

Rx Summit wwwNationalRxDrugAbuseSummitorgSOURCE NCHS Data Visualization Gallery

2005 Rapid Increase in Drug Overdose Death Rates by County

Rx Summit wwwNationalRxDrugAbuseSummitorgSOURCE NCHS Data Visualization Gallery

2010 Rapid Increase in Drug Overdose Death Rates by County

Rx Summit wwwNationalRxDrugAbuseSummitorgSOURCE NCHS Data Visualization Gallery

2016 Rapid Increase in Drug Overdose Death Rates by County

Rx Summit wwwNationalRxDrugAbuseSummitorg

RISE IN OPIOID DEATHS

Overlapping Entangled but Distinct Epidemics

Natural and semi-synthetic opioidslike oxycodone or hydrocodone

Methadone

Heroin

SOURCE National Vital Statistics System Mortality File

Dea

ths

per 1

000

00 p

opul

atio

n

Chart1

Synthetic opioidslike fentanyl
3 Waves
Almost 351630 people have died from an opioid overdose during 1999-2016
Natural and semi-synthetic opioid analgesic
Methadone
Synthetic opioid analgesic excluding methadone
Heroin
1
03
03
07
12
05
03
06
17
1
05
07
19
15
06
07
27
18
07
08
31
15
1
11
37
14
08
14
35
11
1
27
39
1
31
41

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

CDCrsquos Pillars on Opioids Conducting surveillance and research

Building state local and tribal prevention efforts

Supporting healthcare providers and health systems

Partnering with public safety officials

Encouraging consumers to make safe choices about opioids raising awareness about prescription opioid misuse and overdose

Rx Summit wwwNationalRxDrugAbuseSummitorg

Enhanced State Opioid Overdose Surveillance (ESOOS) 12 states funded in September 2016 20 additional states and the

District of Columbia funded in September 2017 (through September 2019)

Strategy One Increase timeliness of non-fatal opioid overdose reporting- Use syndromic surveillance to establish an early warning system to

detect sharp increases or decreases in non-fatal opioid overdoses - Three indicators suspected all-drug opioid and heroin

Alaska California Connecticut Delaware DC Florida Georgia Illinois Indiana Kentucky Louisiana Maine Maryland Massachusetts Michigan Minnesota Missouri Nevada New Hampshire New Jersey New Mexico North Carolina Ohio Oklahoma Pennsylvania Rhode Island Tennessee Utah Vermont Virginia Washington West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

Enhanced State Opioid Overdose Surveillance (ESOOS) Strategy Two Increase timeliness of fatal opioid overdose

reporting- Capture detailed information on toxicology death scene

investigations and other risk factors that may be associated with a fatal overdose

Strategy Three widespread dissemination- Rapidly disseminate surveillance findings to key stakeholders

working to prevent or respond to opioid overdoses

ESOOS program expansion in September 2017- At least 60 for comprehensive toxicology testing for opioid-

involved deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

Funded ESOOS states

Rx Summit wwwNationalRxDrugAbuseSummitorg

Enhanced State Opioid Overdose Surveillance (ESOOS)

Nonfatal Opioid Overdoses Reported

Quarterly

Emergency Department Visits EMS Transports

Fatal Opioid Overdoses Reported within 8 months

of death

Death CertificatesMEC reports

Toxicology reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

Next Two Presentationshellip

The Utilization of Emergency Department Syndromic Surveillance and Emergency Medical Services Data to Monitor Nonfatal Opioid Overdoses ndash Dr Alana Vivolo-Kantor

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System ndash Dr Julie OrsquoDonnell

Rx Summit wwwNationalRxDrugAbuseSummitorg

The utilization of emergency department syndromic surveillance

and emergency medical services data to monitor nonfatal opioid

overdosesPresenter Alana Vivolo-Kantor PhD

Behavioral ScientistCenters for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Julie OrsquoDonnell R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Alana Vivolo-Kantor PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Why Emergency Department and Emergency Medical Service Data for Surveillance

Need- Identify areas experiencing rapid increases in opioid overdoses to

inform responses- More quickly identify promising practices to reduce opioid overdoses

Proven utility to public health and scalable- Local jurisdictions already using it to track and respond to drug

overdoses- Findings from Epi-Aid investigations and collaborative work with states- Leverage existing state and national resources (BioSenseESSENCE)

Action at local and national level- Track quarterly trends across the nation to inform national policy- Improve more rapid local and state public health response

Rx Summit wwwNationalRxDrugAbuseSummitorg

Our Philosophy

Focus on detecting change- Pushing system by looking at trend data over quarters- Some jurisdictions may be able to get and report preliminary

burden estimates

Jurisdiction-driven definitions will outperform national definitions- Local flexibility enhances quality and utility by accounting for large

variance in text entries and coding

National guidance- National definition will provide a good starting place- Guidance to encourage common conceptual definition (eg no

withdrawaldetox) and learn from previous work

Rx Summit wwwNationalRxDrugAbuseSummitorg

Our approach

Non-fatal overdoses

Emergency Department

Near real-time ED collection (ie

syndromic ESSENCE)

Case-level or aggregate data shared

through ESSENCE (BioSense) or directly

with CDC

DischargeBilling Data

Case-level or aggregate data shared

directly with CDC

Emergency Medical Services

Case-level or aggregate data shared

directly with CDC

Includes breakdown by

sex age group and county of residence

Raceethnicity is optional

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency Department Data

Two sources- Near real-time syndromic data (visit information within 24-48 hours)- Lagged hospital billing or claims data (usually within 3-4 weeks)

Different variables used- Discharge diagnosis codes (eg ICD-10-CM) ndash available in billing

data and sometimes in syndromic- Free text fields (eg chief complaint provided by Doctor) ndash

available only in syndromic

Rx Summit wwwNationalRxDrugAbuseSummitorg

Case definitions for suspected overdose

If syndromic- Uses both discharge codes (ie ICD-9-CM ICD-10-CM and

SNOMED) and free text fields such as chief complaint or triage notes

- Free text searches use common terms slang and misspellings (eg herion instead of heroin)

If hospital billing or claimshellip- Uses only discharge codes (ie ICD-9-CM ICD-10-CM and

SNOMED)

Discharge codes use are for acute unintentional or undetermined drug poisoning (eg T401X1A in ICD-10-CM) and may also include some substance useabuse codes (ie F11 in ICD-10-CM)

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency medical services data

Capture potential EMS transports to EDs- Excludes instances where individual is pronounced deceased on

the scene inter-facility transports and when EMTs provide no ldquotreatmentrdquo (eg patient refused or required no treatment or transport)

Different variables used- Chief Complaint Secondary complaint- Narrative- Provider Impression- ICD-1O-CM codes- Medication administered (ie Naloxone)- Response to medication administered (ie awake following

Naloxone administration)

Rx Summit wwwNationalRxDrugAbuseSummitorg

Challenges in EMS data

Transition to newer versions of NEMSIS- Some states working in up to three versions (v221 v334 amp

v340)

Different case definitions in different versions

Missing data feeds

Not all EMS agencies share data

Varying time frame in when data is received- lt24 hours to 6 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Data submission process

Rx Summit wwwNationalRxDrugAbuseSummitorg

Sample quality control report

ObsSTATE YEAR QUARTER ERROR_TEXTTOTAL ED VISITS (GENDER)

TOTAL ED VISITS (AGE)

1XX 2017 1 ED Visits mismatch 98287 98309

2XX 2017 2 ED Visits mismatch 98195 98230

3XX 2017 3 ED Visits mismatch 99167 99205

Rx Summit wwwNationalRxDrugAbuseSummitorg

Sample site report

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results All drug (11 sites)

0

10

20

30

40

50

60

70

80

90

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d al

l dru

g ov

erdo

se ra

tes

by

100

00 E

D v

isits

Quarter year

-2000

-1000

000

1000

2000

3000

4000

5000

6000

7000

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Opioid (11 sites)

0

5

10

15

20

25

30

35

40

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Heroin (11 sites)

0

5

10

15

20

25

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-15

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

Annual percentage changes (11 sites)

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Chart1

All drug
Heroin
Opioid
889150252325
302341597796
208009807928
1075831326045
476222826087
283004552352
167997701832
215786123488
271305063812

table with overall

table with overall

All drug
Suspected all drug overdose rates by 10000 ED visits

Sheet1

All drug

table by sex

Opioid
Quarter year
Suspected opioid overdose rates by 10000 ED visits

table by age

Opioid

table by state

Heroin
Quarter year
Suspected opioid overdose rates by 10000 ED visits
Heroin
All drug
Heroin
Opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Summary

Stable increases for all drug and heroin from Q1 2016 to Q3 2017- Opioid had stable increases from Q3 2016 to Q2 2017

Moderate decreases from Q2 to Q3 2017- 9 for all drug 9 for opioid and 12 for heroin

Annual percentage changes were above 15 increases- Q1 to Q1 89 all drug 30 heroin amp 21 opioid- Q2 to Q2 108 all drug 48 heroin amp 28 opioid- Q3 to Q3 17 all drug 22 heroin amp 27 opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency department data dissemination efforts

ldquoOpioid Overdoses Treated in Emergency Departmentsrdquo -httpswwwcdcgovvitalsignsopioid-overdosesindexhtml

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose

Reporting System

Presenter Julie OrsquoDonnell PhD MPHEpidemiologist

Centers for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Alana Vivolo-Kantor R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Julie OrsquoDonnell PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Increase in deaths outpaces increase in use

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid

overdose

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid overdose surveillance

Track specific substances contributing to overdose deaths

Detect newly-emerging substances involved in overdose

Determine risk factors circumstances associated with fatal overdose

Assess common drug combinations Provide more timely data on overdose deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

State Unintentional Drug Overdose Reporting System (SUDORS)

Death certificates

Medical examiner

coroner reportsToxicology

reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data submitted bi-annually

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

1 Data entry started

2 Data entry finished

1 Data entry started

2 Data entry finished

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS leverages National Violent Death Reporting System (NVDRS) platform

- Basic descriptors- Compare across demographics

- Recent release from institution- Overdose location - Survival time

- Mental health diagnoses- Substance abuse treatment history

- Substances present- Substances contributing to death

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Maine 1941 -1273 225 278 1523 -201 3951 -692 257 -813 2945 981 793 656 -299 -2255 3199 2197
Massachusetts na na na na na na 1561 -157 -848 -1148 311 1897 553 -31 -13 -1632 456 2146
New Hampshire 511 1514 -1438 -832 2583 -961 318 64 -433 -1791 2967 -876 825 -184 -1002 -2016 3363 -17
Pennsylvania na na 869 -102 1211 -116 na na 2979 1751 2589 -594 na na 2601 1534 2735 -735
Rhode Island na na 735 -790 1002 -1594 na na 28 454 544 -1191 na na 121 1057 566 -3262
West Virginia -1596 875 2978 -1543 409 -1651 -367 995 4331 -1664 402 -2377 -769 1847 4571 -1584 -199 -3022
Kentucky -102 1242 -1707 2211 1092 -1468 1095 5192 -2694 4045 352 -2002 -043 5541 -3206 5012 -408 -1624
New Mexico 2932 283 521 -078 445 -716 255 -1298 2611 151 -501 -1093 -487 -3061 3227 987 -1715 323
Missouri 068 -304 754 028 114 421 292 827 477 -177 954 767 -046 1839 096 -512 966 125
Ohio na na 107 1216 1596 -1865 na na 2274 2567 2167 -3194 na na 2182 2254 2086 -3348
Wisconsin -229 1388 861 2928 888 931 -948 986 1712 6728 322 314 -1457 91 983 9621 196 668
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 1514 2112 1966 2017 1853 2398 2634
Massachusetts 7036 8133 8006 7327 6486 6687 7956
New Hampshire 3806 3927 4179 3998 3282 4255 3882
Pennsylvania na na 1265 1641 1929 2428 2284
Rhode Island na na 1498 154 161 1698 1496
West Virginia 2258 2176 2392 3428 2857 2972 2266
Kentucky 2095 2325 3532 258 3624 3752 3001
New Mexico 1927 1976 1719 2168 2201 2091 1862
Missouri 1472 1515 1641 1719 1688 185 1991
Ohio na na 236 2897 3641 443 3015
Wisconsin 664 601 66 773 1294 1336 1377
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 502 9 959 931 721 952 1161
Massachusetts 4035 4258 4126 359 3004 3141 3815
New Hampshire 2514 2721 2671 2403 1919 2564 2128
Pennsylvania na na 1013 1277 1473 1876 1738
Rhode Island na na 803 812 898 949 639
West Virginia 1496 1381 1636 2384 2006 1966 1372
Kentucky 1772 1764 2741 1863 2796 2682 2247
New Mexico 902 858 595 787 865 717 74
Missouri 1002 997 118 1192 1131 124 1255
Ohio na na 1804 2198 2693 3254 2165
Wisconsin 286 244 267 293 575 586 625
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 5609 6697 5845 5976 6142 7078 6936
Massachusetts na na na na na na na
New Hampshire 5678 5968 6872 5883 5394 6787 6135
Pennsylvania na na 8374 9102 9010 10100 9983
Rhode Island na na 3567 3829 3527 3880 3262
West Virginia 4628 3889 4229 5489 4642 4832 4034
Kentucky 6756 6687 7517 6234 7613 8444 7205
New Mexico 5291 6842 7036 7402 7345 7672 7123
Missouri 3213 3235 3137 3373 3383 3421 3565
Ohio na na 8696 8789 9859 11432 9300
Wisconsin 2724 2661 3031 3291 4255 4633 5064
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
15 to 24
25 to 34
35 to 54
55 and up
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Male -140 7355 827 901 1286 -927 742 -758 1157 1241 1306 -829 146 301 1082 1242 1306 -1249
Female 841 5151 103 733 1257 -1521 659 -922 533 1204 1494 -1014 -132 1299 229 1331 1617 -1214
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 4888 4820 8365 9057 9873 11142 10110
Female 3201 3470 5257 5312 5701 6418 5442
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 3611 3879 3585 40 4496 5083 4662
Female 159 1695 1538 162 1816 2087 1875
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 2295 2328 2399 2658 2988 3379 2957
Female 839 828 936 957 1085 126 1107
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017 q1 q2 q3
All drug 3948 4061 6589 6894 7458 8430 7696 889150252325 1075831326045 167997701832
Heroin 1452 1472 1571 1681 1891 2173 191 302341597796 476222826087 215786123488
Opioid 2447 2636 2429 2636 2956 3382 3088 208009807928 283004552352 271305063812
Q12016-Q12017 Q22016-Q22017 Q32016-Q32017
All drug 889150252325 1075831326045 167997701832
Heroin 302341597796 476222826087 215786123488
Opioid 208009807928 283004552352 271305063812
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Heroin 136 674 701 1251 1486 -1209
Opioid 77 -785 853 1212 1442 -868
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Heroin 1452 1472 1571 1681 1891 2173 191
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Heroin 1452 1472 1571 1681 1891 2173 191
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Opioid 77 -785 853 1212 1442 -868
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Heroin 136 674 701 1251 1486 -1209
Q12016-Q12017 Q12016-Q12017 Q12016-Q12017
Q22016-Q22017 Q22016-Q22017 Q22016-Q22017
Q32016-Q32017 Q32016-Q32017 Q32016-Q32017
Column1 Any opioid Natural and semi-synthetic opioid analgesic Methadone Synthetic opioid analgesic excluding methadone Heroin
1999 1 03 03 07
21 1 04 03 07
2001 24 12 05 03 06
32 15 08 04 07
2003 35 17 1 05 07
39 18 13 06 06
2005 43 19 15 06 07
51 23 18 09 07
2007 54 27 18 07 08
57 3 16 08 1
2009 59 31 15 1 11
62 35 15 1 1
2011 66 37 14 08 14
67 35 12 08 19
2013 74 35 11 1 27
86 38 11 18 34
2015 104 39 1 31 41
133 44 1 62 49
1999 1999 1999 1999
1 04 03 07
2001 2001 2001 2001
15 08 04 07
2003 2003 2003 2003
18 13 06 06
2005 2005 2005 2005
23 18 09 07
2007 2007 2007 2007
3 16 08 1
2009 2009 2009 2009
35 15 1 1
2011 2011 2011 2011
35 12 08 19
2013 2013 2013 2013
38 11 18 34
2015 2015 2015 2015
44 1 62 49
Page 3: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosures

All plannersmanagers hereby state that they or their spouselife partner do not have any financial relationships or relationships to products or devices with any commercial interest related to the content of this activity of any amount during the past 12 months

The following plannersmanagers have the following to disclose- Kelly J Clark MD MBA FASAM DFAPA ndash

Consulting fees Braeburn Indivior

Rx Summit wwwNationalRxDrugAbuseSummitorg

Learning Objectives

Describe the process to develop CDC and state case definitions

Identify patterns of recent nonfatal heroin and opioid drug overdoses across 12 states

Identify drugs involved in deaths and circumstances precipitating the deaths based on data

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)

Puja Seth PhDAlana Vivolo-Kantor PhD

Julie OrsquoDonnell PhD

Division of Unintentional Injury PreventionCenters for Disease Control and Prevention

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Puja Seth PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Goals

Describe CDCrsquos new opioid overdose surveillance program Discuss how rapidly available data can be used to inform

overdose response and prevention efforts Overview of emergency department and emergency medical

services data for use in tracking opioid overdose trends Describe the development of case definitions for opioid and

heroin overdose in emergency department and emergency medical services data

Overview of data available for fatal opioid overdoses and associated risk factors and its use in informing prevention and response recommendations

Rx Summit wwwNationalRxDrugAbuseSummitorg

Opioid Overdoses Treated in Emergency Departments

Vivolo-Kantor AM Seth P Gladden RM Mattson CL Baldwin GT Kite-Powell A Coletta MA Vital Signs Trends in Emergency Department Visits for Suspected Opioid Overdoses mdash United States July 2016ndashSeptember 2017(httpswwwcdcgovmmwrvolumes67wrmm6709e1htm) MMWR Morb Mortal Wkly Rep201867

Rx Summit wwwNationalRxDrugAbuseSummitorg

Vivolo-Kantor AM Seth P Gladden RM Mattson CL Baldwin GT Kite-Powell A Coletta MA Vital Signs Trends in Emergency Department Visits for Suspected Opioid Overdoses mdash United States July 2016ndashSeptember 2017(httpswwwcdcgovmmwrvolumes67wrmm6709e1htm) MMWR Morb Mortal Wkly Rep201867

Rx Summit wwwNationalRxDrugAbuseSummitorg

2000 Rapid Increase in Drug Overdose Death Rates by County

SOURCE NCHS Data Visualization Gallery

Rx Summit wwwNationalRxDrugAbuseSummitorgSOURCE NCHS Data Visualization Gallery

2005 Rapid Increase in Drug Overdose Death Rates by County

Rx Summit wwwNationalRxDrugAbuseSummitorgSOURCE NCHS Data Visualization Gallery

2010 Rapid Increase in Drug Overdose Death Rates by County

Rx Summit wwwNationalRxDrugAbuseSummitorgSOURCE NCHS Data Visualization Gallery

2016 Rapid Increase in Drug Overdose Death Rates by County

Rx Summit wwwNationalRxDrugAbuseSummitorg

RISE IN OPIOID DEATHS

Overlapping Entangled but Distinct Epidemics

Natural and semi-synthetic opioidslike oxycodone or hydrocodone

Methadone

Heroin

SOURCE National Vital Statistics System Mortality File

Dea

ths

per 1

000

00 p

opul

atio

n

Chart1

Synthetic opioidslike fentanyl
3 Waves
Almost 351630 people have died from an opioid overdose during 1999-2016
Natural and semi-synthetic opioid analgesic
Methadone
Synthetic opioid analgesic excluding methadone
Heroin
1
03
03
07
12
05
03
06
17
1
05
07
19
15
06
07
27
18
07
08
31
15
1
11
37
14
08
14
35
11
1
27
39
1
31
41

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

CDCrsquos Pillars on Opioids Conducting surveillance and research

Building state local and tribal prevention efforts

Supporting healthcare providers and health systems

Partnering with public safety officials

Encouraging consumers to make safe choices about opioids raising awareness about prescription opioid misuse and overdose

Rx Summit wwwNationalRxDrugAbuseSummitorg

Enhanced State Opioid Overdose Surveillance (ESOOS) 12 states funded in September 2016 20 additional states and the

District of Columbia funded in September 2017 (through September 2019)

Strategy One Increase timeliness of non-fatal opioid overdose reporting- Use syndromic surveillance to establish an early warning system to

detect sharp increases or decreases in non-fatal opioid overdoses - Three indicators suspected all-drug opioid and heroin

Alaska California Connecticut Delaware DC Florida Georgia Illinois Indiana Kentucky Louisiana Maine Maryland Massachusetts Michigan Minnesota Missouri Nevada New Hampshire New Jersey New Mexico North Carolina Ohio Oklahoma Pennsylvania Rhode Island Tennessee Utah Vermont Virginia Washington West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

Enhanced State Opioid Overdose Surveillance (ESOOS) Strategy Two Increase timeliness of fatal opioid overdose

reporting- Capture detailed information on toxicology death scene

investigations and other risk factors that may be associated with a fatal overdose

Strategy Three widespread dissemination- Rapidly disseminate surveillance findings to key stakeholders

working to prevent or respond to opioid overdoses

ESOOS program expansion in September 2017- At least 60 for comprehensive toxicology testing for opioid-

involved deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

Funded ESOOS states

Rx Summit wwwNationalRxDrugAbuseSummitorg

Enhanced State Opioid Overdose Surveillance (ESOOS)

Nonfatal Opioid Overdoses Reported

Quarterly

Emergency Department Visits EMS Transports

Fatal Opioid Overdoses Reported within 8 months

of death

Death CertificatesMEC reports

Toxicology reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

Next Two Presentationshellip

The Utilization of Emergency Department Syndromic Surveillance and Emergency Medical Services Data to Monitor Nonfatal Opioid Overdoses ndash Dr Alana Vivolo-Kantor

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System ndash Dr Julie OrsquoDonnell

Rx Summit wwwNationalRxDrugAbuseSummitorg

The utilization of emergency department syndromic surveillance

and emergency medical services data to monitor nonfatal opioid

overdosesPresenter Alana Vivolo-Kantor PhD

Behavioral ScientistCenters for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Julie OrsquoDonnell R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Alana Vivolo-Kantor PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Why Emergency Department and Emergency Medical Service Data for Surveillance

Need- Identify areas experiencing rapid increases in opioid overdoses to

inform responses- More quickly identify promising practices to reduce opioid overdoses

Proven utility to public health and scalable- Local jurisdictions already using it to track and respond to drug

overdoses- Findings from Epi-Aid investigations and collaborative work with states- Leverage existing state and national resources (BioSenseESSENCE)

Action at local and national level- Track quarterly trends across the nation to inform national policy- Improve more rapid local and state public health response

Rx Summit wwwNationalRxDrugAbuseSummitorg

Our Philosophy

Focus on detecting change- Pushing system by looking at trend data over quarters- Some jurisdictions may be able to get and report preliminary

burden estimates

Jurisdiction-driven definitions will outperform national definitions- Local flexibility enhances quality and utility by accounting for large

variance in text entries and coding

National guidance- National definition will provide a good starting place- Guidance to encourage common conceptual definition (eg no

withdrawaldetox) and learn from previous work

Rx Summit wwwNationalRxDrugAbuseSummitorg

Our approach

Non-fatal overdoses

Emergency Department

Near real-time ED collection (ie

syndromic ESSENCE)

Case-level or aggregate data shared

through ESSENCE (BioSense) or directly

with CDC

DischargeBilling Data

Case-level or aggregate data shared

directly with CDC

Emergency Medical Services

Case-level or aggregate data shared

directly with CDC

Includes breakdown by

sex age group and county of residence

Raceethnicity is optional

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency Department Data

Two sources- Near real-time syndromic data (visit information within 24-48 hours)- Lagged hospital billing or claims data (usually within 3-4 weeks)

Different variables used- Discharge diagnosis codes (eg ICD-10-CM) ndash available in billing

data and sometimes in syndromic- Free text fields (eg chief complaint provided by Doctor) ndash

available only in syndromic

Rx Summit wwwNationalRxDrugAbuseSummitorg

Case definitions for suspected overdose

If syndromic- Uses both discharge codes (ie ICD-9-CM ICD-10-CM and

SNOMED) and free text fields such as chief complaint or triage notes

- Free text searches use common terms slang and misspellings (eg herion instead of heroin)

If hospital billing or claimshellip- Uses only discharge codes (ie ICD-9-CM ICD-10-CM and

SNOMED)

Discharge codes use are for acute unintentional or undetermined drug poisoning (eg T401X1A in ICD-10-CM) and may also include some substance useabuse codes (ie F11 in ICD-10-CM)

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency medical services data

Capture potential EMS transports to EDs- Excludes instances where individual is pronounced deceased on

the scene inter-facility transports and when EMTs provide no ldquotreatmentrdquo (eg patient refused or required no treatment or transport)

Different variables used- Chief Complaint Secondary complaint- Narrative- Provider Impression- ICD-1O-CM codes- Medication administered (ie Naloxone)- Response to medication administered (ie awake following

Naloxone administration)

Rx Summit wwwNationalRxDrugAbuseSummitorg

Challenges in EMS data

Transition to newer versions of NEMSIS- Some states working in up to three versions (v221 v334 amp

v340)

Different case definitions in different versions

Missing data feeds

Not all EMS agencies share data

Varying time frame in when data is received- lt24 hours to 6 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Data submission process

Rx Summit wwwNationalRxDrugAbuseSummitorg

Sample quality control report

ObsSTATE YEAR QUARTER ERROR_TEXTTOTAL ED VISITS (GENDER)

TOTAL ED VISITS (AGE)

1XX 2017 1 ED Visits mismatch 98287 98309

2XX 2017 2 ED Visits mismatch 98195 98230

3XX 2017 3 ED Visits mismatch 99167 99205

Rx Summit wwwNationalRxDrugAbuseSummitorg

Sample site report

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results All drug (11 sites)

0

10

20

30

40

50

60

70

80

90

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d al

l dru

g ov

erdo

se ra

tes

by

100

00 E

D v

isits

Quarter year

-2000

-1000

000

1000

2000

3000

4000

5000

6000

7000

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Opioid (11 sites)

0

5

10

15

20

25

30

35

40

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Heroin (11 sites)

0

5

10

15

20

25

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-15

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

Annual percentage changes (11 sites)

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Chart1

All drug
Heroin
Opioid
889150252325
302341597796
208009807928
1075831326045
476222826087
283004552352
167997701832
215786123488
271305063812

table with overall

table with overall

All drug
Suspected all drug overdose rates by 10000 ED visits

Sheet1

All drug

table by sex

Opioid
Quarter year
Suspected opioid overdose rates by 10000 ED visits

table by age

Opioid

table by state

Heroin
Quarter year
Suspected opioid overdose rates by 10000 ED visits
Heroin
All drug
Heroin
Opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Summary

Stable increases for all drug and heroin from Q1 2016 to Q3 2017- Opioid had stable increases from Q3 2016 to Q2 2017

Moderate decreases from Q2 to Q3 2017- 9 for all drug 9 for opioid and 12 for heroin

Annual percentage changes were above 15 increases- Q1 to Q1 89 all drug 30 heroin amp 21 opioid- Q2 to Q2 108 all drug 48 heroin amp 28 opioid- Q3 to Q3 17 all drug 22 heroin amp 27 opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency department data dissemination efforts

ldquoOpioid Overdoses Treated in Emergency Departmentsrdquo -httpswwwcdcgovvitalsignsopioid-overdosesindexhtml

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose

Reporting System

Presenter Julie OrsquoDonnell PhD MPHEpidemiologist

Centers for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Alana Vivolo-Kantor R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Julie OrsquoDonnell PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Increase in deaths outpaces increase in use

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid

overdose

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid overdose surveillance

Track specific substances contributing to overdose deaths

Detect newly-emerging substances involved in overdose

Determine risk factors circumstances associated with fatal overdose

Assess common drug combinations Provide more timely data on overdose deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

State Unintentional Drug Overdose Reporting System (SUDORS)

Death certificates

Medical examiner

coroner reportsToxicology

reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data submitted bi-annually

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

1 Data entry started

2 Data entry finished

1 Data entry started

2 Data entry finished

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS leverages National Violent Death Reporting System (NVDRS) platform

- Basic descriptors- Compare across demographics

- Recent release from institution- Overdose location - Survival time

- Mental health diagnoses- Substance abuse treatment history

- Substances present- Substances contributing to death

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Maine 1941 -1273 225 278 1523 -201 3951 -692 257 -813 2945 981 793 656 -299 -2255 3199 2197
Massachusetts na na na na na na 1561 -157 -848 -1148 311 1897 553 -31 -13 -1632 456 2146
New Hampshire 511 1514 -1438 -832 2583 -961 318 64 -433 -1791 2967 -876 825 -184 -1002 -2016 3363 -17
Pennsylvania na na 869 -102 1211 -116 na na 2979 1751 2589 -594 na na 2601 1534 2735 -735
Rhode Island na na 735 -790 1002 -1594 na na 28 454 544 -1191 na na 121 1057 566 -3262
West Virginia -1596 875 2978 -1543 409 -1651 -367 995 4331 -1664 402 -2377 -769 1847 4571 -1584 -199 -3022
Kentucky -102 1242 -1707 2211 1092 -1468 1095 5192 -2694 4045 352 -2002 -043 5541 -3206 5012 -408 -1624
New Mexico 2932 283 521 -078 445 -716 255 -1298 2611 151 -501 -1093 -487 -3061 3227 987 -1715 323
Missouri 068 -304 754 028 114 421 292 827 477 -177 954 767 -046 1839 096 -512 966 125
Ohio na na 107 1216 1596 -1865 na na 2274 2567 2167 -3194 na na 2182 2254 2086 -3348
Wisconsin -229 1388 861 2928 888 931 -948 986 1712 6728 322 314 -1457 91 983 9621 196 668
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 1514 2112 1966 2017 1853 2398 2634
Massachusetts 7036 8133 8006 7327 6486 6687 7956
New Hampshire 3806 3927 4179 3998 3282 4255 3882
Pennsylvania na na 1265 1641 1929 2428 2284
Rhode Island na na 1498 154 161 1698 1496
West Virginia 2258 2176 2392 3428 2857 2972 2266
Kentucky 2095 2325 3532 258 3624 3752 3001
New Mexico 1927 1976 1719 2168 2201 2091 1862
Missouri 1472 1515 1641 1719 1688 185 1991
Ohio na na 236 2897 3641 443 3015
Wisconsin 664 601 66 773 1294 1336 1377
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 502 9 959 931 721 952 1161
Massachusetts 4035 4258 4126 359 3004 3141 3815
New Hampshire 2514 2721 2671 2403 1919 2564 2128
Pennsylvania na na 1013 1277 1473 1876 1738
Rhode Island na na 803 812 898 949 639
West Virginia 1496 1381 1636 2384 2006 1966 1372
Kentucky 1772 1764 2741 1863 2796 2682 2247
New Mexico 902 858 595 787 865 717 74
Missouri 1002 997 118 1192 1131 124 1255
Ohio na na 1804 2198 2693 3254 2165
Wisconsin 286 244 267 293 575 586 625
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 5609 6697 5845 5976 6142 7078 6936
Massachusetts na na na na na na na
New Hampshire 5678 5968 6872 5883 5394 6787 6135
Pennsylvania na na 8374 9102 9010 10100 9983
Rhode Island na na 3567 3829 3527 3880 3262
West Virginia 4628 3889 4229 5489 4642 4832 4034
Kentucky 6756 6687 7517 6234 7613 8444 7205
New Mexico 5291 6842 7036 7402 7345 7672 7123
Missouri 3213 3235 3137 3373 3383 3421 3565
Ohio na na 8696 8789 9859 11432 9300
Wisconsin 2724 2661 3031 3291 4255 4633 5064
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
15 to 24
25 to 34
35 to 54
55 and up
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Male -140 7355 827 901 1286 -927 742 -758 1157 1241 1306 -829 146 301 1082 1242 1306 -1249
Female 841 5151 103 733 1257 -1521 659 -922 533 1204 1494 -1014 -132 1299 229 1331 1617 -1214
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 4888 4820 8365 9057 9873 11142 10110
Female 3201 3470 5257 5312 5701 6418 5442
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 3611 3879 3585 40 4496 5083 4662
Female 159 1695 1538 162 1816 2087 1875
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 2295 2328 2399 2658 2988 3379 2957
Female 839 828 936 957 1085 126 1107
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017 q1 q2 q3
All drug 3948 4061 6589 6894 7458 8430 7696 889150252325 1075831326045 167997701832
Heroin 1452 1472 1571 1681 1891 2173 191 302341597796 476222826087 215786123488
Opioid 2447 2636 2429 2636 2956 3382 3088 208009807928 283004552352 271305063812
Q12016-Q12017 Q22016-Q22017 Q32016-Q32017
All drug 889150252325 1075831326045 167997701832
Heroin 302341597796 476222826087 215786123488
Opioid 208009807928 283004552352 271305063812
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Heroin 136 674 701 1251 1486 -1209
Opioid 77 -785 853 1212 1442 -868
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Heroin 1452 1472 1571 1681 1891 2173 191
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Heroin 1452 1472 1571 1681 1891 2173 191
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Opioid 77 -785 853 1212 1442 -868
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Heroin 136 674 701 1251 1486 -1209
Q12016-Q12017 Q12016-Q12017 Q12016-Q12017
Q22016-Q22017 Q22016-Q22017 Q22016-Q22017
Q32016-Q32017 Q32016-Q32017 Q32016-Q32017
Column1 Any opioid Natural and semi-synthetic opioid analgesic Methadone Synthetic opioid analgesic excluding methadone Heroin
1999 1 03 03 07
21 1 04 03 07
2001 24 12 05 03 06
32 15 08 04 07
2003 35 17 1 05 07
39 18 13 06 06
2005 43 19 15 06 07
51 23 18 09 07
2007 54 27 18 07 08
57 3 16 08 1
2009 59 31 15 1 11
62 35 15 1 1
2011 66 37 14 08 14
67 35 12 08 19
2013 74 35 11 1 27
86 38 11 18 34
2015 104 39 1 31 41
133 44 1 62 49
1999 1999 1999 1999
1 04 03 07
2001 2001 2001 2001
15 08 04 07
2003 2003 2003 2003
18 13 06 06
2005 2005 2005 2005
23 18 09 07
2007 2007 2007 2007
3 16 08 1
2009 2009 2009 2009
35 15 1 1
2011 2011 2011 2011
35 12 08 19
2013 2013 2013 2013
38 11 18 34
2015 2015 2015 2015
44 1 62 49
Page 4: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

Learning Objectives

Describe the process to develop CDC and state case definitions

Identify patterns of recent nonfatal heroin and opioid drug overdoses across 12 states

Identify drugs involved in deaths and circumstances precipitating the deaths based on data

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)

Puja Seth PhDAlana Vivolo-Kantor PhD

Julie OrsquoDonnell PhD

Division of Unintentional Injury PreventionCenters for Disease Control and Prevention

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Puja Seth PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Goals

Describe CDCrsquos new opioid overdose surveillance program Discuss how rapidly available data can be used to inform

overdose response and prevention efforts Overview of emergency department and emergency medical

services data for use in tracking opioid overdose trends Describe the development of case definitions for opioid and

heroin overdose in emergency department and emergency medical services data

Overview of data available for fatal opioid overdoses and associated risk factors and its use in informing prevention and response recommendations

Rx Summit wwwNationalRxDrugAbuseSummitorg

Opioid Overdoses Treated in Emergency Departments

Vivolo-Kantor AM Seth P Gladden RM Mattson CL Baldwin GT Kite-Powell A Coletta MA Vital Signs Trends in Emergency Department Visits for Suspected Opioid Overdoses mdash United States July 2016ndashSeptember 2017(httpswwwcdcgovmmwrvolumes67wrmm6709e1htm) MMWR Morb Mortal Wkly Rep201867

Rx Summit wwwNationalRxDrugAbuseSummitorg

Vivolo-Kantor AM Seth P Gladden RM Mattson CL Baldwin GT Kite-Powell A Coletta MA Vital Signs Trends in Emergency Department Visits for Suspected Opioid Overdoses mdash United States July 2016ndashSeptember 2017(httpswwwcdcgovmmwrvolumes67wrmm6709e1htm) MMWR Morb Mortal Wkly Rep201867

Rx Summit wwwNationalRxDrugAbuseSummitorg

2000 Rapid Increase in Drug Overdose Death Rates by County

SOURCE NCHS Data Visualization Gallery

Rx Summit wwwNationalRxDrugAbuseSummitorgSOURCE NCHS Data Visualization Gallery

2005 Rapid Increase in Drug Overdose Death Rates by County

Rx Summit wwwNationalRxDrugAbuseSummitorgSOURCE NCHS Data Visualization Gallery

2010 Rapid Increase in Drug Overdose Death Rates by County

Rx Summit wwwNationalRxDrugAbuseSummitorgSOURCE NCHS Data Visualization Gallery

2016 Rapid Increase in Drug Overdose Death Rates by County

Rx Summit wwwNationalRxDrugAbuseSummitorg

RISE IN OPIOID DEATHS

Overlapping Entangled but Distinct Epidemics

Natural and semi-synthetic opioidslike oxycodone or hydrocodone

Methadone

Heroin

SOURCE National Vital Statistics System Mortality File

Dea

ths

per 1

000

00 p

opul

atio

n

Chart1

Synthetic opioidslike fentanyl
3 Waves
Almost 351630 people have died from an opioid overdose during 1999-2016
Natural and semi-synthetic opioid analgesic
Methadone
Synthetic opioid analgesic excluding methadone
Heroin
1
03
03
07
12
05
03
06
17
1
05
07
19
15
06
07
27
18
07
08
31
15
1
11
37
14
08
14
35
11
1
27
39
1
31
41

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

CDCrsquos Pillars on Opioids Conducting surveillance and research

Building state local and tribal prevention efforts

Supporting healthcare providers and health systems

Partnering with public safety officials

Encouraging consumers to make safe choices about opioids raising awareness about prescription opioid misuse and overdose

Rx Summit wwwNationalRxDrugAbuseSummitorg

Enhanced State Opioid Overdose Surveillance (ESOOS) 12 states funded in September 2016 20 additional states and the

District of Columbia funded in September 2017 (through September 2019)

Strategy One Increase timeliness of non-fatal opioid overdose reporting- Use syndromic surveillance to establish an early warning system to

detect sharp increases or decreases in non-fatal opioid overdoses - Three indicators suspected all-drug opioid and heroin

Alaska California Connecticut Delaware DC Florida Georgia Illinois Indiana Kentucky Louisiana Maine Maryland Massachusetts Michigan Minnesota Missouri Nevada New Hampshire New Jersey New Mexico North Carolina Ohio Oklahoma Pennsylvania Rhode Island Tennessee Utah Vermont Virginia Washington West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

Enhanced State Opioid Overdose Surveillance (ESOOS) Strategy Two Increase timeliness of fatal opioid overdose

reporting- Capture detailed information on toxicology death scene

investigations and other risk factors that may be associated with a fatal overdose

Strategy Three widespread dissemination- Rapidly disseminate surveillance findings to key stakeholders

working to prevent or respond to opioid overdoses

ESOOS program expansion in September 2017- At least 60 for comprehensive toxicology testing for opioid-

involved deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

Funded ESOOS states

Rx Summit wwwNationalRxDrugAbuseSummitorg

Enhanced State Opioid Overdose Surveillance (ESOOS)

Nonfatal Opioid Overdoses Reported

Quarterly

Emergency Department Visits EMS Transports

Fatal Opioid Overdoses Reported within 8 months

of death

Death CertificatesMEC reports

Toxicology reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

Next Two Presentationshellip

The Utilization of Emergency Department Syndromic Surveillance and Emergency Medical Services Data to Monitor Nonfatal Opioid Overdoses ndash Dr Alana Vivolo-Kantor

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System ndash Dr Julie OrsquoDonnell

Rx Summit wwwNationalRxDrugAbuseSummitorg

The utilization of emergency department syndromic surveillance

and emergency medical services data to monitor nonfatal opioid

overdosesPresenter Alana Vivolo-Kantor PhD

Behavioral ScientistCenters for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Julie OrsquoDonnell R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Alana Vivolo-Kantor PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Why Emergency Department and Emergency Medical Service Data for Surveillance

Need- Identify areas experiencing rapid increases in opioid overdoses to

inform responses- More quickly identify promising practices to reduce opioid overdoses

Proven utility to public health and scalable- Local jurisdictions already using it to track and respond to drug

overdoses- Findings from Epi-Aid investigations and collaborative work with states- Leverage existing state and national resources (BioSenseESSENCE)

Action at local and national level- Track quarterly trends across the nation to inform national policy- Improve more rapid local and state public health response

Rx Summit wwwNationalRxDrugAbuseSummitorg

Our Philosophy

Focus on detecting change- Pushing system by looking at trend data over quarters- Some jurisdictions may be able to get and report preliminary

burden estimates

Jurisdiction-driven definitions will outperform national definitions- Local flexibility enhances quality and utility by accounting for large

variance in text entries and coding

National guidance- National definition will provide a good starting place- Guidance to encourage common conceptual definition (eg no

withdrawaldetox) and learn from previous work

Rx Summit wwwNationalRxDrugAbuseSummitorg

Our approach

Non-fatal overdoses

Emergency Department

Near real-time ED collection (ie

syndromic ESSENCE)

Case-level or aggregate data shared

through ESSENCE (BioSense) or directly

with CDC

DischargeBilling Data

Case-level or aggregate data shared

directly with CDC

Emergency Medical Services

Case-level or aggregate data shared

directly with CDC

Includes breakdown by

sex age group and county of residence

Raceethnicity is optional

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency Department Data

Two sources- Near real-time syndromic data (visit information within 24-48 hours)- Lagged hospital billing or claims data (usually within 3-4 weeks)

Different variables used- Discharge diagnosis codes (eg ICD-10-CM) ndash available in billing

data and sometimes in syndromic- Free text fields (eg chief complaint provided by Doctor) ndash

available only in syndromic

Rx Summit wwwNationalRxDrugAbuseSummitorg

Case definitions for suspected overdose

If syndromic- Uses both discharge codes (ie ICD-9-CM ICD-10-CM and

SNOMED) and free text fields such as chief complaint or triage notes

- Free text searches use common terms slang and misspellings (eg herion instead of heroin)

If hospital billing or claimshellip- Uses only discharge codes (ie ICD-9-CM ICD-10-CM and

SNOMED)

Discharge codes use are for acute unintentional or undetermined drug poisoning (eg T401X1A in ICD-10-CM) and may also include some substance useabuse codes (ie F11 in ICD-10-CM)

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency medical services data

Capture potential EMS transports to EDs- Excludes instances where individual is pronounced deceased on

the scene inter-facility transports and when EMTs provide no ldquotreatmentrdquo (eg patient refused or required no treatment or transport)

Different variables used- Chief Complaint Secondary complaint- Narrative- Provider Impression- ICD-1O-CM codes- Medication administered (ie Naloxone)- Response to medication administered (ie awake following

Naloxone administration)

Rx Summit wwwNationalRxDrugAbuseSummitorg

Challenges in EMS data

Transition to newer versions of NEMSIS- Some states working in up to three versions (v221 v334 amp

v340)

Different case definitions in different versions

Missing data feeds

Not all EMS agencies share data

Varying time frame in when data is received- lt24 hours to 6 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Data submission process

Rx Summit wwwNationalRxDrugAbuseSummitorg

Sample quality control report

ObsSTATE YEAR QUARTER ERROR_TEXTTOTAL ED VISITS (GENDER)

TOTAL ED VISITS (AGE)

1XX 2017 1 ED Visits mismatch 98287 98309

2XX 2017 2 ED Visits mismatch 98195 98230

3XX 2017 3 ED Visits mismatch 99167 99205

Rx Summit wwwNationalRxDrugAbuseSummitorg

Sample site report

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results All drug (11 sites)

0

10

20

30

40

50

60

70

80

90

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d al

l dru

g ov

erdo

se ra

tes

by

100

00 E

D v

isits

Quarter year

-2000

-1000

000

1000

2000

3000

4000

5000

6000

7000

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Opioid (11 sites)

0

5

10

15

20

25

30

35

40

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Heroin (11 sites)

0

5

10

15

20

25

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-15

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

Annual percentage changes (11 sites)

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Chart1

All drug
Heroin
Opioid
889150252325
302341597796
208009807928
1075831326045
476222826087
283004552352
167997701832
215786123488
271305063812

table with overall

table with overall

All drug
Suspected all drug overdose rates by 10000 ED visits

Sheet1

All drug

table by sex

Opioid
Quarter year
Suspected opioid overdose rates by 10000 ED visits

table by age

Opioid

table by state

Heroin
Quarter year
Suspected opioid overdose rates by 10000 ED visits
Heroin
All drug
Heroin
Opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Summary

Stable increases for all drug and heroin from Q1 2016 to Q3 2017- Opioid had stable increases from Q3 2016 to Q2 2017

Moderate decreases from Q2 to Q3 2017- 9 for all drug 9 for opioid and 12 for heroin

Annual percentage changes were above 15 increases- Q1 to Q1 89 all drug 30 heroin amp 21 opioid- Q2 to Q2 108 all drug 48 heroin amp 28 opioid- Q3 to Q3 17 all drug 22 heroin amp 27 opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency department data dissemination efforts

ldquoOpioid Overdoses Treated in Emergency Departmentsrdquo -httpswwwcdcgovvitalsignsopioid-overdosesindexhtml

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose

Reporting System

Presenter Julie OrsquoDonnell PhD MPHEpidemiologist

Centers for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Alana Vivolo-Kantor R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Julie OrsquoDonnell PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Increase in deaths outpaces increase in use

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid

overdose

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid overdose surveillance

Track specific substances contributing to overdose deaths

Detect newly-emerging substances involved in overdose

Determine risk factors circumstances associated with fatal overdose

Assess common drug combinations Provide more timely data on overdose deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

State Unintentional Drug Overdose Reporting System (SUDORS)

Death certificates

Medical examiner

coroner reportsToxicology

reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data submitted bi-annually

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

1 Data entry started

2 Data entry finished

1 Data entry started

2 Data entry finished

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS leverages National Violent Death Reporting System (NVDRS) platform

- Basic descriptors- Compare across demographics

- Recent release from institution- Overdose location - Survival time

- Mental health diagnoses- Substance abuse treatment history

- Substances present- Substances contributing to death

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Maine 1941 -1273 225 278 1523 -201 3951 -692 257 -813 2945 981 793 656 -299 -2255 3199 2197
Massachusetts na na na na na na 1561 -157 -848 -1148 311 1897 553 -31 -13 -1632 456 2146
New Hampshire 511 1514 -1438 -832 2583 -961 318 64 -433 -1791 2967 -876 825 -184 -1002 -2016 3363 -17
Pennsylvania na na 869 -102 1211 -116 na na 2979 1751 2589 -594 na na 2601 1534 2735 -735
Rhode Island na na 735 -790 1002 -1594 na na 28 454 544 -1191 na na 121 1057 566 -3262
West Virginia -1596 875 2978 -1543 409 -1651 -367 995 4331 -1664 402 -2377 -769 1847 4571 -1584 -199 -3022
Kentucky -102 1242 -1707 2211 1092 -1468 1095 5192 -2694 4045 352 -2002 -043 5541 -3206 5012 -408 -1624
New Mexico 2932 283 521 -078 445 -716 255 -1298 2611 151 -501 -1093 -487 -3061 3227 987 -1715 323
Missouri 068 -304 754 028 114 421 292 827 477 -177 954 767 -046 1839 096 -512 966 125
Ohio na na 107 1216 1596 -1865 na na 2274 2567 2167 -3194 na na 2182 2254 2086 -3348
Wisconsin -229 1388 861 2928 888 931 -948 986 1712 6728 322 314 -1457 91 983 9621 196 668
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 1514 2112 1966 2017 1853 2398 2634
Massachusetts 7036 8133 8006 7327 6486 6687 7956
New Hampshire 3806 3927 4179 3998 3282 4255 3882
Pennsylvania na na 1265 1641 1929 2428 2284
Rhode Island na na 1498 154 161 1698 1496
West Virginia 2258 2176 2392 3428 2857 2972 2266
Kentucky 2095 2325 3532 258 3624 3752 3001
New Mexico 1927 1976 1719 2168 2201 2091 1862
Missouri 1472 1515 1641 1719 1688 185 1991
Ohio na na 236 2897 3641 443 3015
Wisconsin 664 601 66 773 1294 1336 1377
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 502 9 959 931 721 952 1161
Massachusetts 4035 4258 4126 359 3004 3141 3815
New Hampshire 2514 2721 2671 2403 1919 2564 2128
Pennsylvania na na 1013 1277 1473 1876 1738
Rhode Island na na 803 812 898 949 639
West Virginia 1496 1381 1636 2384 2006 1966 1372
Kentucky 1772 1764 2741 1863 2796 2682 2247
New Mexico 902 858 595 787 865 717 74
Missouri 1002 997 118 1192 1131 124 1255
Ohio na na 1804 2198 2693 3254 2165
Wisconsin 286 244 267 293 575 586 625
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 5609 6697 5845 5976 6142 7078 6936
Massachusetts na na na na na na na
New Hampshire 5678 5968 6872 5883 5394 6787 6135
Pennsylvania na na 8374 9102 9010 10100 9983
Rhode Island na na 3567 3829 3527 3880 3262
West Virginia 4628 3889 4229 5489 4642 4832 4034
Kentucky 6756 6687 7517 6234 7613 8444 7205
New Mexico 5291 6842 7036 7402 7345 7672 7123
Missouri 3213 3235 3137 3373 3383 3421 3565
Ohio na na 8696 8789 9859 11432 9300
Wisconsin 2724 2661 3031 3291 4255 4633 5064
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
15 to 24
25 to 34
35 to 54
55 and up
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Male -140 7355 827 901 1286 -927 742 -758 1157 1241 1306 -829 146 301 1082 1242 1306 -1249
Female 841 5151 103 733 1257 -1521 659 -922 533 1204 1494 -1014 -132 1299 229 1331 1617 -1214
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 4888 4820 8365 9057 9873 11142 10110
Female 3201 3470 5257 5312 5701 6418 5442
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 3611 3879 3585 40 4496 5083 4662
Female 159 1695 1538 162 1816 2087 1875
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 2295 2328 2399 2658 2988 3379 2957
Female 839 828 936 957 1085 126 1107
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017 q1 q2 q3
All drug 3948 4061 6589 6894 7458 8430 7696 889150252325 1075831326045 167997701832
Heroin 1452 1472 1571 1681 1891 2173 191 302341597796 476222826087 215786123488
Opioid 2447 2636 2429 2636 2956 3382 3088 208009807928 283004552352 271305063812
Q12016-Q12017 Q22016-Q22017 Q32016-Q32017
All drug 889150252325 1075831326045 167997701832
Heroin 302341597796 476222826087 215786123488
Opioid 208009807928 283004552352 271305063812
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Heroin 136 674 701 1251 1486 -1209
Opioid 77 -785 853 1212 1442 -868
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Heroin 1452 1472 1571 1681 1891 2173 191
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Heroin 1452 1472 1571 1681 1891 2173 191
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Opioid 77 -785 853 1212 1442 -868
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Heroin 136 674 701 1251 1486 -1209
Q12016-Q12017 Q12016-Q12017 Q12016-Q12017
Q22016-Q22017 Q22016-Q22017 Q22016-Q22017
Q32016-Q32017 Q32016-Q32017 Q32016-Q32017
Column1 Any opioid Natural and semi-synthetic opioid analgesic Methadone Synthetic opioid analgesic excluding methadone Heroin
1999 1 03 03 07
21 1 04 03 07
2001 24 12 05 03 06
32 15 08 04 07
2003 35 17 1 05 07
39 18 13 06 06
2005 43 19 15 06 07
51 23 18 09 07
2007 54 27 18 07 08
57 3 16 08 1
2009 59 31 15 1 11
62 35 15 1 1
2011 66 37 14 08 14
67 35 12 08 19
2013 74 35 11 1 27
86 38 11 18 34
2015 104 39 1 31 41
133 44 1 62 49
1999 1999 1999 1999
1 04 03 07
2001 2001 2001 2001
15 08 04 07
2003 2003 2003 2003
18 13 06 06
2005 2005 2005 2005
23 18 09 07
2007 2007 2007 2007
3 16 08 1
2009 2009 2009 2009
35 15 1 1
2011 2011 2011 2011
35 12 08 19
2013 2013 2013 2013
38 11 18 34
2015 2015 2015 2015
44 1 62 49
Page 5: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)

Puja Seth PhDAlana Vivolo-Kantor PhD

Julie OrsquoDonnell PhD

Division of Unintentional Injury PreventionCenters for Disease Control and Prevention

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Puja Seth PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Goals

Describe CDCrsquos new opioid overdose surveillance program Discuss how rapidly available data can be used to inform

overdose response and prevention efforts Overview of emergency department and emergency medical

services data for use in tracking opioid overdose trends Describe the development of case definitions for opioid and

heroin overdose in emergency department and emergency medical services data

Overview of data available for fatal opioid overdoses and associated risk factors and its use in informing prevention and response recommendations

Rx Summit wwwNationalRxDrugAbuseSummitorg

Opioid Overdoses Treated in Emergency Departments

Vivolo-Kantor AM Seth P Gladden RM Mattson CL Baldwin GT Kite-Powell A Coletta MA Vital Signs Trends in Emergency Department Visits for Suspected Opioid Overdoses mdash United States July 2016ndashSeptember 2017(httpswwwcdcgovmmwrvolumes67wrmm6709e1htm) MMWR Morb Mortal Wkly Rep201867

Rx Summit wwwNationalRxDrugAbuseSummitorg

Vivolo-Kantor AM Seth P Gladden RM Mattson CL Baldwin GT Kite-Powell A Coletta MA Vital Signs Trends in Emergency Department Visits for Suspected Opioid Overdoses mdash United States July 2016ndashSeptember 2017(httpswwwcdcgovmmwrvolumes67wrmm6709e1htm) MMWR Morb Mortal Wkly Rep201867

Rx Summit wwwNationalRxDrugAbuseSummitorg

2000 Rapid Increase in Drug Overdose Death Rates by County

SOURCE NCHS Data Visualization Gallery

Rx Summit wwwNationalRxDrugAbuseSummitorgSOURCE NCHS Data Visualization Gallery

2005 Rapid Increase in Drug Overdose Death Rates by County

Rx Summit wwwNationalRxDrugAbuseSummitorgSOURCE NCHS Data Visualization Gallery

2010 Rapid Increase in Drug Overdose Death Rates by County

Rx Summit wwwNationalRxDrugAbuseSummitorgSOURCE NCHS Data Visualization Gallery

2016 Rapid Increase in Drug Overdose Death Rates by County

Rx Summit wwwNationalRxDrugAbuseSummitorg

RISE IN OPIOID DEATHS

Overlapping Entangled but Distinct Epidemics

Natural and semi-synthetic opioidslike oxycodone or hydrocodone

Methadone

Heroin

SOURCE National Vital Statistics System Mortality File

Dea

ths

per 1

000

00 p

opul

atio

n

Chart1

Synthetic opioidslike fentanyl
3 Waves
Almost 351630 people have died from an opioid overdose during 1999-2016
Natural and semi-synthetic opioid analgesic
Methadone
Synthetic opioid analgesic excluding methadone
Heroin
1
03
03
07
12
05
03
06
17
1
05
07
19
15
06
07
27
18
07
08
31
15
1
11
37
14
08
14
35
11
1
27
39
1
31
41

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

CDCrsquos Pillars on Opioids Conducting surveillance and research

Building state local and tribal prevention efforts

Supporting healthcare providers and health systems

Partnering with public safety officials

Encouraging consumers to make safe choices about opioids raising awareness about prescription opioid misuse and overdose

Rx Summit wwwNationalRxDrugAbuseSummitorg

Enhanced State Opioid Overdose Surveillance (ESOOS) 12 states funded in September 2016 20 additional states and the

District of Columbia funded in September 2017 (through September 2019)

Strategy One Increase timeliness of non-fatal opioid overdose reporting- Use syndromic surveillance to establish an early warning system to

detect sharp increases or decreases in non-fatal opioid overdoses - Three indicators suspected all-drug opioid and heroin

Alaska California Connecticut Delaware DC Florida Georgia Illinois Indiana Kentucky Louisiana Maine Maryland Massachusetts Michigan Minnesota Missouri Nevada New Hampshire New Jersey New Mexico North Carolina Ohio Oklahoma Pennsylvania Rhode Island Tennessee Utah Vermont Virginia Washington West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

Enhanced State Opioid Overdose Surveillance (ESOOS) Strategy Two Increase timeliness of fatal opioid overdose

reporting- Capture detailed information on toxicology death scene

investigations and other risk factors that may be associated with a fatal overdose

Strategy Three widespread dissemination- Rapidly disseminate surveillance findings to key stakeholders

working to prevent or respond to opioid overdoses

ESOOS program expansion in September 2017- At least 60 for comprehensive toxicology testing for opioid-

involved deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

Funded ESOOS states

Rx Summit wwwNationalRxDrugAbuseSummitorg

Enhanced State Opioid Overdose Surveillance (ESOOS)

Nonfatal Opioid Overdoses Reported

Quarterly

Emergency Department Visits EMS Transports

Fatal Opioid Overdoses Reported within 8 months

of death

Death CertificatesMEC reports

Toxicology reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

Next Two Presentationshellip

The Utilization of Emergency Department Syndromic Surveillance and Emergency Medical Services Data to Monitor Nonfatal Opioid Overdoses ndash Dr Alana Vivolo-Kantor

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System ndash Dr Julie OrsquoDonnell

Rx Summit wwwNationalRxDrugAbuseSummitorg

The utilization of emergency department syndromic surveillance

and emergency medical services data to monitor nonfatal opioid

overdosesPresenter Alana Vivolo-Kantor PhD

Behavioral ScientistCenters for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Julie OrsquoDonnell R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Alana Vivolo-Kantor PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Why Emergency Department and Emergency Medical Service Data for Surveillance

Need- Identify areas experiencing rapid increases in opioid overdoses to

inform responses- More quickly identify promising practices to reduce opioid overdoses

Proven utility to public health and scalable- Local jurisdictions already using it to track and respond to drug

overdoses- Findings from Epi-Aid investigations and collaborative work with states- Leverage existing state and national resources (BioSenseESSENCE)

Action at local and national level- Track quarterly trends across the nation to inform national policy- Improve more rapid local and state public health response

Rx Summit wwwNationalRxDrugAbuseSummitorg

Our Philosophy

Focus on detecting change- Pushing system by looking at trend data over quarters- Some jurisdictions may be able to get and report preliminary

burden estimates

Jurisdiction-driven definitions will outperform national definitions- Local flexibility enhances quality and utility by accounting for large

variance in text entries and coding

National guidance- National definition will provide a good starting place- Guidance to encourage common conceptual definition (eg no

withdrawaldetox) and learn from previous work

Rx Summit wwwNationalRxDrugAbuseSummitorg

Our approach

Non-fatal overdoses

Emergency Department

Near real-time ED collection (ie

syndromic ESSENCE)

Case-level or aggregate data shared

through ESSENCE (BioSense) or directly

with CDC

DischargeBilling Data

Case-level or aggregate data shared

directly with CDC

Emergency Medical Services

Case-level or aggregate data shared

directly with CDC

Includes breakdown by

sex age group and county of residence

Raceethnicity is optional

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency Department Data

Two sources- Near real-time syndromic data (visit information within 24-48 hours)- Lagged hospital billing or claims data (usually within 3-4 weeks)

Different variables used- Discharge diagnosis codes (eg ICD-10-CM) ndash available in billing

data and sometimes in syndromic- Free text fields (eg chief complaint provided by Doctor) ndash

available only in syndromic

Rx Summit wwwNationalRxDrugAbuseSummitorg

Case definitions for suspected overdose

If syndromic- Uses both discharge codes (ie ICD-9-CM ICD-10-CM and

SNOMED) and free text fields such as chief complaint or triage notes

- Free text searches use common terms slang and misspellings (eg herion instead of heroin)

If hospital billing or claimshellip- Uses only discharge codes (ie ICD-9-CM ICD-10-CM and

SNOMED)

Discharge codes use are for acute unintentional or undetermined drug poisoning (eg T401X1A in ICD-10-CM) and may also include some substance useabuse codes (ie F11 in ICD-10-CM)

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency medical services data

Capture potential EMS transports to EDs- Excludes instances where individual is pronounced deceased on

the scene inter-facility transports and when EMTs provide no ldquotreatmentrdquo (eg patient refused or required no treatment or transport)

Different variables used- Chief Complaint Secondary complaint- Narrative- Provider Impression- ICD-1O-CM codes- Medication administered (ie Naloxone)- Response to medication administered (ie awake following

Naloxone administration)

Rx Summit wwwNationalRxDrugAbuseSummitorg

Challenges in EMS data

Transition to newer versions of NEMSIS- Some states working in up to three versions (v221 v334 amp

v340)

Different case definitions in different versions

Missing data feeds

Not all EMS agencies share data

Varying time frame in when data is received- lt24 hours to 6 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Data submission process

Rx Summit wwwNationalRxDrugAbuseSummitorg

Sample quality control report

ObsSTATE YEAR QUARTER ERROR_TEXTTOTAL ED VISITS (GENDER)

TOTAL ED VISITS (AGE)

1XX 2017 1 ED Visits mismatch 98287 98309

2XX 2017 2 ED Visits mismatch 98195 98230

3XX 2017 3 ED Visits mismatch 99167 99205

Rx Summit wwwNationalRxDrugAbuseSummitorg

Sample site report

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results All drug (11 sites)

0

10

20

30

40

50

60

70

80

90

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d al

l dru

g ov

erdo

se ra

tes

by

100

00 E

D v

isits

Quarter year

-2000

-1000

000

1000

2000

3000

4000

5000

6000

7000

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Opioid (11 sites)

0

5

10

15

20

25

30

35

40

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Heroin (11 sites)

0

5

10

15

20

25

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-15

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

Annual percentage changes (11 sites)

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Chart1

All drug
Heroin
Opioid
889150252325
302341597796
208009807928
1075831326045
476222826087
283004552352
167997701832
215786123488
271305063812

table with overall

table with overall

All drug
Suspected all drug overdose rates by 10000 ED visits

Sheet1

All drug

table by sex

Opioid
Quarter year
Suspected opioid overdose rates by 10000 ED visits

table by age

Opioid

table by state

Heroin
Quarter year
Suspected opioid overdose rates by 10000 ED visits
Heroin
All drug
Heroin
Opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Summary

Stable increases for all drug and heroin from Q1 2016 to Q3 2017- Opioid had stable increases from Q3 2016 to Q2 2017

Moderate decreases from Q2 to Q3 2017- 9 for all drug 9 for opioid and 12 for heroin

Annual percentage changes were above 15 increases- Q1 to Q1 89 all drug 30 heroin amp 21 opioid- Q2 to Q2 108 all drug 48 heroin amp 28 opioid- Q3 to Q3 17 all drug 22 heroin amp 27 opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency department data dissemination efforts

ldquoOpioid Overdoses Treated in Emergency Departmentsrdquo -httpswwwcdcgovvitalsignsopioid-overdosesindexhtml

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose

Reporting System

Presenter Julie OrsquoDonnell PhD MPHEpidemiologist

Centers for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Alana Vivolo-Kantor R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Julie OrsquoDonnell PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Increase in deaths outpaces increase in use

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid

overdose

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid overdose surveillance

Track specific substances contributing to overdose deaths

Detect newly-emerging substances involved in overdose

Determine risk factors circumstances associated with fatal overdose

Assess common drug combinations Provide more timely data on overdose deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

State Unintentional Drug Overdose Reporting System (SUDORS)

Death certificates

Medical examiner

coroner reportsToxicology

reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data submitted bi-annually

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

1 Data entry started

2 Data entry finished

1 Data entry started

2 Data entry finished

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS leverages National Violent Death Reporting System (NVDRS) platform

- Basic descriptors- Compare across demographics

- Recent release from institution- Overdose location - Survival time

- Mental health diagnoses- Substance abuse treatment history

- Substances present- Substances contributing to death

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Maine 1941 -1273 225 278 1523 -201 3951 -692 257 -813 2945 981 793 656 -299 -2255 3199 2197
Massachusetts na na na na na na 1561 -157 -848 -1148 311 1897 553 -31 -13 -1632 456 2146
New Hampshire 511 1514 -1438 -832 2583 -961 318 64 -433 -1791 2967 -876 825 -184 -1002 -2016 3363 -17
Pennsylvania na na 869 -102 1211 -116 na na 2979 1751 2589 -594 na na 2601 1534 2735 -735
Rhode Island na na 735 -790 1002 -1594 na na 28 454 544 -1191 na na 121 1057 566 -3262
West Virginia -1596 875 2978 -1543 409 -1651 -367 995 4331 -1664 402 -2377 -769 1847 4571 -1584 -199 -3022
Kentucky -102 1242 -1707 2211 1092 -1468 1095 5192 -2694 4045 352 -2002 -043 5541 -3206 5012 -408 -1624
New Mexico 2932 283 521 -078 445 -716 255 -1298 2611 151 -501 -1093 -487 -3061 3227 987 -1715 323
Missouri 068 -304 754 028 114 421 292 827 477 -177 954 767 -046 1839 096 -512 966 125
Ohio na na 107 1216 1596 -1865 na na 2274 2567 2167 -3194 na na 2182 2254 2086 -3348
Wisconsin -229 1388 861 2928 888 931 -948 986 1712 6728 322 314 -1457 91 983 9621 196 668
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 1514 2112 1966 2017 1853 2398 2634
Massachusetts 7036 8133 8006 7327 6486 6687 7956
New Hampshire 3806 3927 4179 3998 3282 4255 3882
Pennsylvania na na 1265 1641 1929 2428 2284
Rhode Island na na 1498 154 161 1698 1496
West Virginia 2258 2176 2392 3428 2857 2972 2266
Kentucky 2095 2325 3532 258 3624 3752 3001
New Mexico 1927 1976 1719 2168 2201 2091 1862
Missouri 1472 1515 1641 1719 1688 185 1991
Ohio na na 236 2897 3641 443 3015
Wisconsin 664 601 66 773 1294 1336 1377
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 502 9 959 931 721 952 1161
Massachusetts 4035 4258 4126 359 3004 3141 3815
New Hampshire 2514 2721 2671 2403 1919 2564 2128
Pennsylvania na na 1013 1277 1473 1876 1738
Rhode Island na na 803 812 898 949 639
West Virginia 1496 1381 1636 2384 2006 1966 1372
Kentucky 1772 1764 2741 1863 2796 2682 2247
New Mexico 902 858 595 787 865 717 74
Missouri 1002 997 118 1192 1131 124 1255
Ohio na na 1804 2198 2693 3254 2165
Wisconsin 286 244 267 293 575 586 625
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 5609 6697 5845 5976 6142 7078 6936
Massachusetts na na na na na na na
New Hampshire 5678 5968 6872 5883 5394 6787 6135
Pennsylvania na na 8374 9102 9010 10100 9983
Rhode Island na na 3567 3829 3527 3880 3262
West Virginia 4628 3889 4229 5489 4642 4832 4034
Kentucky 6756 6687 7517 6234 7613 8444 7205
New Mexico 5291 6842 7036 7402 7345 7672 7123
Missouri 3213 3235 3137 3373 3383 3421 3565
Ohio na na 8696 8789 9859 11432 9300
Wisconsin 2724 2661 3031 3291 4255 4633 5064
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
15 to 24
25 to 34
35 to 54
55 and up
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Male -140 7355 827 901 1286 -927 742 -758 1157 1241 1306 -829 146 301 1082 1242 1306 -1249
Female 841 5151 103 733 1257 -1521 659 -922 533 1204 1494 -1014 -132 1299 229 1331 1617 -1214
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 4888 4820 8365 9057 9873 11142 10110
Female 3201 3470 5257 5312 5701 6418 5442
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 3611 3879 3585 40 4496 5083 4662
Female 159 1695 1538 162 1816 2087 1875
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 2295 2328 2399 2658 2988 3379 2957
Female 839 828 936 957 1085 126 1107
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017 q1 q2 q3
All drug 3948 4061 6589 6894 7458 8430 7696 889150252325 1075831326045 167997701832
Heroin 1452 1472 1571 1681 1891 2173 191 302341597796 476222826087 215786123488
Opioid 2447 2636 2429 2636 2956 3382 3088 208009807928 283004552352 271305063812
Q12016-Q12017 Q22016-Q22017 Q32016-Q32017
All drug 889150252325 1075831326045 167997701832
Heroin 302341597796 476222826087 215786123488
Opioid 208009807928 283004552352 271305063812
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Heroin 136 674 701 1251 1486 -1209
Opioid 77 -785 853 1212 1442 -868
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Heroin 1452 1472 1571 1681 1891 2173 191
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Heroin 1452 1472 1571 1681 1891 2173 191
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Opioid 77 -785 853 1212 1442 -868
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Heroin 136 674 701 1251 1486 -1209
Q12016-Q12017 Q12016-Q12017 Q12016-Q12017
Q22016-Q22017 Q22016-Q22017 Q22016-Q22017
Q32016-Q32017 Q32016-Q32017 Q32016-Q32017
Column1 Any opioid Natural and semi-synthetic opioid analgesic Methadone Synthetic opioid analgesic excluding methadone Heroin
1999 1 03 03 07
21 1 04 03 07
2001 24 12 05 03 06
32 15 08 04 07
2003 35 17 1 05 07
39 18 13 06 06
2005 43 19 15 06 07
51 23 18 09 07
2007 54 27 18 07 08
57 3 16 08 1
2009 59 31 15 1 11
62 35 15 1 1
2011 66 37 14 08 14
67 35 12 08 19
2013 74 35 11 1 27
86 38 11 18 34
2015 104 39 1 31 41
133 44 1 62 49
1999 1999 1999 1999
1 04 03 07
2001 2001 2001 2001
15 08 04 07
2003 2003 2003 2003
18 13 06 06
2005 2005 2005 2005
23 18 09 07
2007 2007 2007 2007
3 16 08 1
2009 2009 2009 2009
35 15 1 1
2011 2011 2011 2011
35 12 08 19
2013 2013 2013 2013
38 11 18 34
2015 2015 2015 2015
44 1 62 49
Page 6: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Puja Seth PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Goals

Describe CDCrsquos new opioid overdose surveillance program Discuss how rapidly available data can be used to inform

overdose response and prevention efforts Overview of emergency department and emergency medical

services data for use in tracking opioid overdose trends Describe the development of case definitions for opioid and

heroin overdose in emergency department and emergency medical services data

Overview of data available for fatal opioid overdoses and associated risk factors and its use in informing prevention and response recommendations

Rx Summit wwwNationalRxDrugAbuseSummitorg

Opioid Overdoses Treated in Emergency Departments

Vivolo-Kantor AM Seth P Gladden RM Mattson CL Baldwin GT Kite-Powell A Coletta MA Vital Signs Trends in Emergency Department Visits for Suspected Opioid Overdoses mdash United States July 2016ndashSeptember 2017(httpswwwcdcgovmmwrvolumes67wrmm6709e1htm) MMWR Morb Mortal Wkly Rep201867

Rx Summit wwwNationalRxDrugAbuseSummitorg

Vivolo-Kantor AM Seth P Gladden RM Mattson CL Baldwin GT Kite-Powell A Coletta MA Vital Signs Trends in Emergency Department Visits for Suspected Opioid Overdoses mdash United States July 2016ndashSeptember 2017(httpswwwcdcgovmmwrvolumes67wrmm6709e1htm) MMWR Morb Mortal Wkly Rep201867

Rx Summit wwwNationalRxDrugAbuseSummitorg

2000 Rapid Increase in Drug Overdose Death Rates by County

SOURCE NCHS Data Visualization Gallery

Rx Summit wwwNationalRxDrugAbuseSummitorgSOURCE NCHS Data Visualization Gallery

2005 Rapid Increase in Drug Overdose Death Rates by County

Rx Summit wwwNationalRxDrugAbuseSummitorgSOURCE NCHS Data Visualization Gallery

2010 Rapid Increase in Drug Overdose Death Rates by County

Rx Summit wwwNationalRxDrugAbuseSummitorgSOURCE NCHS Data Visualization Gallery

2016 Rapid Increase in Drug Overdose Death Rates by County

Rx Summit wwwNationalRxDrugAbuseSummitorg

RISE IN OPIOID DEATHS

Overlapping Entangled but Distinct Epidemics

Natural and semi-synthetic opioidslike oxycodone or hydrocodone

Methadone

Heroin

SOURCE National Vital Statistics System Mortality File

Dea

ths

per 1

000

00 p

opul

atio

n

Chart1

Synthetic opioidslike fentanyl
3 Waves
Almost 351630 people have died from an opioid overdose during 1999-2016
Natural and semi-synthetic opioid analgesic
Methadone
Synthetic opioid analgesic excluding methadone
Heroin
1
03
03
07
12
05
03
06
17
1
05
07
19
15
06
07
27
18
07
08
31
15
1
11
37
14
08
14
35
11
1
27
39
1
31
41

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

CDCrsquos Pillars on Opioids Conducting surveillance and research

Building state local and tribal prevention efforts

Supporting healthcare providers and health systems

Partnering with public safety officials

Encouraging consumers to make safe choices about opioids raising awareness about prescription opioid misuse and overdose

Rx Summit wwwNationalRxDrugAbuseSummitorg

Enhanced State Opioid Overdose Surveillance (ESOOS) 12 states funded in September 2016 20 additional states and the

District of Columbia funded in September 2017 (through September 2019)

Strategy One Increase timeliness of non-fatal opioid overdose reporting- Use syndromic surveillance to establish an early warning system to

detect sharp increases or decreases in non-fatal opioid overdoses - Three indicators suspected all-drug opioid and heroin

Alaska California Connecticut Delaware DC Florida Georgia Illinois Indiana Kentucky Louisiana Maine Maryland Massachusetts Michigan Minnesota Missouri Nevada New Hampshire New Jersey New Mexico North Carolina Ohio Oklahoma Pennsylvania Rhode Island Tennessee Utah Vermont Virginia Washington West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

Enhanced State Opioid Overdose Surveillance (ESOOS) Strategy Two Increase timeliness of fatal opioid overdose

reporting- Capture detailed information on toxicology death scene

investigations and other risk factors that may be associated with a fatal overdose

Strategy Three widespread dissemination- Rapidly disseminate surveillance findings to key stakeholders

working to prevent or respond to opioid overdoses

ESOOS program expansion in September 2017- At least 60 for comprehensive toxicology testing for opioid-

involved deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

Funded ESOOS states

Rx Summit wwwNationalRxDrugAbuseSummitorg

Enhanced State Opioid Overdose Surveillance (ESOOS)

Nonfatal Opioid Overdoses Reported

Quarterly

Emergency Department Visits EMS Transports

Fatal Opioid Overdoses Reported within 8 months

of death

Death CertificatesMEC reports

Toxicology reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

Next Two Presentationshellip

The Utilization of Emergency Department Syndromic Surveillance and Emergency Medical Services Data to Monitor Nonfatal Opioid Overdoses ndash Dr Alana Vivolo-Kantor

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System ndash Dr Julie OrsquoDonnell

Rx Summit wwwNationalRxDrugAbuseSummitorg

The utilization of emergency department syndromic surveillance

and emergency medical services data to monitor nonfatal opioid

overdosesPresenter Alana Vivolo-Kantor PhD

Behavioral ScientistCenters for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Julie OrsquoDonnell R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Alana Vivolo-Kantor PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Why Emergency Department and Emergency Medical Service Data for Surveillance

Need- Identify areas experiencing rapid increases in opioid overdoses to

inform responses- More quickly identify promising practices to reduce opioid overdoses

Proven utility to public health and scalable- Local jurisdictions already using it to track and respond to drug

overdoses- Findings from Epi-Aid investigations and collaborative work with states- Leverage existing state and national resources (BioSenseESSENCE)

Action at local and national level- Track quarterly trends across the nation to inform national policy- Improve more rapid local and state public health response

Rx Summit wwwNationalRxDrugAbuseSummitorg

Our Philosophy

Focus on detecting change- Pushing system by looking at trend data over quarters- Some jurisdictions may be able to get and report preliminary

burden estimates

Jurisdiction-driven definitions will outperform national definitions- Local flexibility enhances quality and utility by accounting for large

variance in text entries and coding

National guidance- National definition will provide a good starting place- Guidance to encourage common conceptual definition (eg no

withdrawaldetox) and learn from previous work

Rx Summit wwwNationalRxDrugAbuseSummitorg

Our approach

Non-fatal overdoses

Emergency Department

Near real-time ED collection (ie

syndromic ESSENCE)

Case-level or aggregate data shared

through ESSENCE (BioSense) or directly

with CDC

DischargeBilling Data

Case-level or aggregate data shared

directly with CDC

Emergency Medical Services

Case-level or aggregate data shared

directly with CDC

Includes breakdown by

sex age group and county of residence

Raceethnicity is optional

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency Department Data

Two sources- Near real-time syndromic data (visit information within 24-48 hours)- Lagged hospital billing or claims data (usually within 3-4 weeks)

Different variables used- Discharge diagnosis codes (eg ICD-10-CM) ndash available in billing

data and sometimes in syndromic- Free text fields (eg chief complaint provided by Doctor) ndash

available only in syndromic

Rx Summit wwwNationalRxDrugAbuseSummitorg

Case definitions for suspected overdose

If syndromic- Uses both discharge codes (ie ICD-9-CM ICD-10-CM and

SNOMED) and free text fields such as chief complaint or triage notes

- Free text searches use common terms slang and misspellings (eg herion instead of heroin)

If hospital billing or claimshellip- Uses only discharge codes (ie ICD-9-CM ICD-10-CM and

SNOMED)

Discharge codes use are for acute unintentional or undetermined drug poisoning (eg T401X1A in ICD-10-CM) and may also include some substance useabuse codes (ie F11 in ICD-10-CM)

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency medical services data

Capture potential EMS transports to EDs- Excludes instances where individual is pronounced deceased on

the scene inter-facility transports and when EMTs provide no ldquotreatmentrdquo (eg patient refused or required no treatment or transport)

Different variables used- Chief Complaint Secondary complaint- Narrative- Provider Impression- ICD-1O-CM codes- Medication administered (ie Naloxone)- Response to medication administered (ie awake following

Naloxone administration)

Rx Summit wwwNationalRxDrugAbuseSummitorg

Challenges in EMS data

Transition to newer versions of NEMSIS- Some states working in up to three versions (v221 v334 amp

v340)

Different case definitions in different versions

Missing data feeds

Not all EMS agencies share data

Varying time frame in when data is received- lt24 hours to 6 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Data submission process

Rx Summit wwwNationalRxDrugAbuseSummitorg

Sample quality control report

ObsSTATE YEAR QUARTER ERROR_TEXTTOTAL ED VISITS (GENDER)

TOTAL ED VISITS (AGE)

1XX 2017 1 ED Visits mismatch 98287 98309

2XX 2017 2 ED Visits mismatch 98195 98230

3XX 2017 3 ED Visits mismatch 99167 99205

Rx Summit wwwNationalRxDrugAbuseSummitorg

Sample site report

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results All drug (11 sites)

0

10

20

30

40

50

60

70

80

90

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d al

l dru

g ov

erdo

se ra

tes

by

100

00 E

D v

isits

Quarter year

-2000

-1000

000

1000

2000

3000

4000

5000

6000

7000

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Opioid (11 sites)

0

5

10

15

20

25

30

35

40

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Heroin (11 sites)

0

5

10

15

20

25

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-15

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

Annual percentage changes (11 sites)

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Chart1

All drug
Heroin
Opioid
889150252325
302341597796
208009807928
1075831326045
476222826087
283004552352
167997701832
215786123488
271305063812

table with overall

table with overall

All drug
Suspected all drug overdose rates by 10000 ED visits

Sheet1

All drug

table by sex

Opioid
Quarter year
Suspected opioid overdose rates by 10000 ED visits

table by age

Opioid

table by state

Heroin
Quarter year
Suspected opioid overdose rates by 10000 ED visits
Heroin
All drug
Heroin
Opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Summary

Stable increases for all drug and heroin from Q1 2016 to Q3 2017- Opioid had stable increases from Q3 2016 to Q2 2017

Moderate decreases from Q2 to Q3 2017- 9 for all drug 9 for opioid and 12 for heroin

Annual percentage changes were above 15 increases- Q1 to Q1 89 all drug 30 heroin amp 21 opioid- Q2 to Q2 108 all drug 48 heroin amp 28 opioid- Q3 to Q3 17 all drug 22 heroin amp 27 opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency department data dissemination efforts

ldquoOpioid Overdoses Treated in Emergency Departmentsrdquo -httpswwwcdcgovvitalsignsopioid-overdosesindexhtml

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose

Reporting System

Presenter Julie OrsquoDonnell PhD MPHEpidemiologist

Centers for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Alana Vivolo-Kantor R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Julie OrsquoDonnell PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Increase in deaths outpaces increase in use

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid

overdose

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid overdose surveillance

Track specific substances contributing to overdose deaths

Detect newly-emerging substances involved in overdose

Determine risk factors circumstances associated with fatal overdose

Assess common drug combinations Provide more timely data on overdose deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

State Unintentional Drug Overdose Reporting System (SUDORS)

Death certificates

Medical examiner

coroner reportsToxicology

reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data submitted bi-annually

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

1 Data entry started

2 Data entry finished

1 Data entry started

2 Data entry finished

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS leverages National Violent Death Reporting System (NVDRS) platform

- Basic descriptors- Compare across demographics

- Recent release from institution- Overdose location - Survival time

- Mental health diagnoses- Substance abuse treatment history

- Substances present- Substances contributing to death

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Maine 1941 -1273 225 278 1523 -201 3951 -692 257 -813 2945 981 793 656 -299 -2255 3199 2197
Massachusetts na na na na na na 1561 -157 -848 -1148 311 1897 553 -31 -13 -1632 456 2146
New Hampshire 511 1514 -1438 -832 2583 -961 318 64 -433 -1791 2967 -876 825 -184 -1002 -2016 3363 -17
Pennsylvania na na 869 -102 1211 -116 na na 2979 1751 2589 -594 na na 2601 1534 2735 -735
Rhode Island na na 735 -790 1002 -1594 na na 28 454 544 -1191 na na 121 1057 566 -3262
West Virginia -1596 875 2978 -1543 409 -1651 -367 995 4331 -1664 402 -2377 -769 1847 4571 -1584 -199 -3022
Kentucky -102 1242 -1707 2211 1092 -1468 1095 5192 -2694 4045 352 -2002 -043 5541 -3206 5012 -408 -1624
New Mexico 2932 283 521 -078 445 -716 255 -1298 2611 151 -501 -1093 -487 -3061 3227 987 -1715 323
Missouri 068 -304 754 028 114 421 292 827 477 -177 954 767 -046 1839 096 -512 966 125
Ohio na na 107 1216 1596 -1865 na na 2274 2567 2167 -3194 na na 2182 2254 2086 -3348
Wisconsin -229 1388 861 2928 888 931 -948 986 1712 6728 322 314 -1457 91 983 9621 196 668
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 1514 2112 1966 2017 1853 2398 2634
Massachusetts 7036 8133 8006 7327 6486 6687 7956
New Hampshire 3806 3927 4179 3998 3282 4255 3882
Pennsylvania na na 1265 1641 1929 2428 2284
Rhode Island na na 1498 154 161 1698 1496
West Virginia 2258 2176 2392 3428 2857 2972 2266
Kentucky 2095 2325 3532 258 3624 3752 3001
New Mexico 1927 1976 1719 2168 2201 2091 1862
Missouri 1472 1515 1641 1719 1688 185 1991
Ohio na na 236 2897 3641 443 3015
Wisconsin 664 601 66 773 1294 1336 1377
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 502 9 959 931 721 952 1161
Massachusetts 4035 4258 4126 359 3004 3141 3815
New Hampshire 2514 2721 2671 2403 1919 2564 2128
Pennsylvania na na 1013 1277 1473 1876 1738
Rhode Island na na 803 812 898 949 639
West Virginia 1496 1381 1636 2384 2006 1966 1372
Kentucky 1772 1764 2741 1863 2796 2682 2247
New Mexico 902 858 595 787 865 717 74
Missouri 1002 997 118 1192 1131 124 1255
Ohio na na 1804 2198 2693 3254 2165
Wisconsin 286 244 267 293 575 586 625
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 5609 6697 5845 5976 6142 7078 6936
Massachusetts na na na na na na na
New Hampshire 5678 5968 6872 5883 5394 6787 6135
Pennsylvania na na 8374 9102 9010 10100 9983
Rhode Island na na 3567 3829 3527 3880 3262
West Virginia 4628 3889 4229 5489 4642 4832 4034
Kentucky 6756 6687 7517 6234 7613 8444 7205
New Mexico 5291 6842 7036 7402 7345 7672 7123
Missouri 3213 3235 3137 3373 3383 3421 3565
Ohio na na 8696 8789 9859 11432 9300
Wisconsin 2724 2661 3031 3291 4255 4633 5064
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
15 to 24
25 to 34
35 to 54
55 and up
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Male -140 7355 827 901 1286 -927 742 -758 1157 1241 1306 -829 146 301 1082 1242 1306 -1249
Female 841 5151 103 733 1257 -1521 659 -922 533 1204 1494 -1014 -132 1299 229 1331 1617 -1214
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 4888 4820 8365 9057 9873 11142 10110
Female 3201 3470 5257 5312 5701 6418 5442
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 3611 3879 3585 40 4496 5083 4662
Female 159 1695 1538 162 1816 2087 1875
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 2295 2328 2399 2658 2988 3379 2957
Female 839 828 936 957 1085 126 1107
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017 q1 q2 q3
All drug 3948 4061 6589 6894 7458 8430 7696 889150252325 1075831326045 167997701832
Heroin 1452 1472 1571 1681 1891 2173 191 302341597796 476222826087 215786123488
Opioid 2447 2636 2429 2636 2956 3382 3088 208009807928 283004552352 271305063812
Q12016-Q12017 Q22016-Q22017 Q32016-Q32017
All drug 889150252325 1075831326045 167997701832
Heroin 302341597796 476222826087 215786123488
Opioid 208009807928 283004552352 271305063812
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Heroin 136 674 701 1251 1486 -1209
Opioid 77 -785 853 1212 1442 -868
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Heroin 1452 1472 1571 1681 1891 2173 191
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Heroin 1452 1472 1571 1681 1891 2173 191
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Opioid 77 -785 853 1212 1442 -868
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Heroin 136 674 701 1251 1486 -1209
Q12016-Q12017 Q12016-Q12017 Q12016-Q12017
Q22016-Q22017 Q22016-Q22017 Q22016-Q22017
Q32016-Q32017 Q32016-Q32017 Q32016-Q32017
Column1 Any opioid Natural and semi-synthetic opioid analgesic Methadone Synthetic opioid analgesic excluding methadone Heroin
1999 1 03 03 07
21 1 04 03 07
2001 24 12 05 03 06
32 15 08 04 07
2003 35 17 1 05 07
39 18 13 06 06
2005 43 19 15 06 07
51 23 18 09 07
2007 54 27 18 07 08
57 3 16 08 1
2009 59 31 15 1 11
62 35 15 1 1
2011 66 37 14 08 14
67 35 12 08 19
2013 74 35 11 1 27
86 38 11 18 34
2015 104 39 1 31 41
133 44 1 62 49
1999 1999 1999 1999
1 04 03 07
2001 2001 2001 2001
15 08 04 07
2003 2003 2003 2003
18 13 06 06
2005 2005 2005 2005
23 18 09 07
2007 2007 2007 2007
3 16 08 1
2009 2009 2009 2009
35 15 1 1
2011 2011 2011 2011
35 12 08 19
2013 2013 2013 2013
38 11 18 34
2015 2015 2015 2015
44 1 62 49
Page 7: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

Goals

Describe CDCrsquos new opioid overdose surveillance program Discuss how rapidly available data can be used to inform

overdose response and prevention efforts Overview of emergency department and emergency medical

services data for use in tracking opioid overdose trends Describe the development of case definitions for opioid and

heroin overdose in emergency department and emergency medical services data

Overview of data available for fatal opioid overdoses and associated risk factors and its use in informing prevention and response recommendations

Rx Summit wwwNationalRxDrugAbuseSummitorg

Opioid Overdoses Treated in Emergency Departments

Vivolo-Kantor AM Seth P Gladden RM Mattson CL Baldwin GT Kite-Powell A Coletta MA Vital Signs Trends in Emergency Department Visits for Suspected Opioid Overdoses mdash United States July 2016ndashSeptember 2017(httpswwwcdcgovmmwrvolumes67wrmm6709e1htm) MMWR Morb Mortal Wkly Rep201867

Rx Summit wwwNationalRxDrugAbuseSummitorg

Vivolo-Kantor AM Seth P Gladden RM Mattson CL Baldwin GT Kite-Powell A Coletta MA Vital Signs Trends in Emergency Department Visits for Suspected Opioid Overdoses mdash United States July 2016ndashSeptember 2017(httpswwwcdcgovmmwrvolumes67wrmm6709e1htm) MMWR Morb Mortal Wkly Rep201867

Rx Summit wwwNationalRxDrugAbuseSummitorg

2000 Rapid Increase in Drug Overdose Death Rates by County

SOURCE NCHS Data Visualization Gallery

Rx Summit wwwNationalRxDrugAbuseSummitorgSOURCE NCHS Data Visualization Gallery

2005 Rapid Increase in Drug Overdose Death Rates by County

Rx Summit wwwNationalRxDrugAbuseSummitorgSOURCE NCHS Data Visualization Gallery

2010 Rapid Increase in Drug Overdose Death Rates by County

Rx Summit wwwNationalRxDrugAbuseSummitorgSOURCE NCHS Data Visualization Gallery

2016 Rapid Increase in Drug Overdose Death Rates by County

Rx Summit wwwNationalRxDrugAbuseSummitorg

RISE IN OPIOID DEATHS

Overlapping Entangled but Distinct Epidemics

Natural and semi-synthetic opioidslike oxycodone or hydrocodone

Methadone

Heroin

SOURCE National Vital Statistics System Mortality File

Dea

ths

per 1

000

00 p

opul

atio

n

Chart1

Synthetic opioidslike fentanyl
3 Waves
Almost 351630 people have died from an opioid overdose during 1999-2016
Natural and semi-synthetic opioid analgesic
Methadone
Synthetic opioid analgesic excluding methadone
Heroin
1
03
03
07
12
05
03
06
17
1
05
07
19
15
06
07
27
18
07
08
31
15
1
11
37
14
08
14
35
11
1
27
39
1
31
41

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

CDCrsquos Pillars on Opioids Conducting surveillance and research

Building state local and tribal prevention efforts

Supporting healthcare providers and health systems

Partnering with public safety officials

Encouraging consumers to make safe choices about opioids raising awareness about prescription opioid misuse and overdose

Rx Summit wwwNationalRxDrugAbuseSummitorg

Enhanced State Opioid Overdose Surveillance (ESOOS) 12 states funded in September 2016 20 additional states and the

District of Columbia funded in September 2017 (through September 2019)

Strategy One Increase timeliness of non-fatal opioid overdose reporting- Use syndromic surveillance to establish an early warning system to

detect sharp increases or decreases in non-fatal opioid overdoses - Three indicators suspected all-drug opioid and heroin

Alaska California Connecticut Delaware DC Florida Georgia Illinois Indiana Kentucky Louisiana Maine Maryland Massachusetts Michigan Minnesota Missouri Nevada New Hampshire New Jersey New Mexico North Carolina Ohio Oklahoma Pennsylvania Rhode Island Tennessee Utah Vermont Virginia Washington West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

Enhanced State Opioid Overdose Surveillance (ESOOS) Strategy Two Increase timeliness of fatal opioid overdose

reporting- Capture detailed information on toxicology death scene

investigations and other risk factors that may be associated with a fatal overdose

Strategy Three widespread dissemination- Rapidly disseminate surveillance findings to key stakeholders

working to prevent or respond to opioid overdoses

ESOOS program expansion in September 2017- At least 60 for comprehensive toxicology testing for opioid-

involved deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

Funded ESOOS states

Rx Summit wwwNationalRxDrugAbuseSummitorg

Enhanced State Opioid Overdose Surveillance (ESOOS)

Nonfatal Opioid Overdoses Reported

Quarterly

Emergency Department Visits EMS Transports

Fatal Opioid Overdoses Reported within 8 months

of death

Death CertificatesMEC reports

Toxicology reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

Next Two Presentationshellip

The Utilization of Emergency Department Syndromic Surveillance and Emergency Medical Services Data to Monitor Nonfatal Opioid Overdoses ndash Dr Alana Vivolo-Kantor

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System ndash Dr Julie OrsquoDonnell

Rx Summit wwwNationalRxDrugAbuseSummitorg

The utilization of emergency department syndromic surveillance

and emergency medical services data to monitor nonfatal opioid

overdosesPresenter Alana Vivolo-Kantor PhD

Behavioral ScientistCenters for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Julie OrsquoDonnell R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Alana Vivolo-Kantor PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Why Emergency Department and Emergency Medical Service Data for Surveillance

Need- Identify areas experiencing rapid increases in opioid overdoses to

inform responses- More quickly identify promising practices to reduce opioid overdoses

Proven utility to public health and scalable- Local jurisdictions already using it to track and respond to drug

overdoses- Findings from Epi-Aid investigations and collaborative work with states- Leverage existing state and national resources (BioSenseESSENCE)

Action at local and national level- Track quarterly trends across the nation to inform national policy- Improve more rapid local and state public health response

Rx Summit wwwNationalRxDrugAbuseSummitorg

Our Philosophy

Focus on detecting change- Pushing system by looking at trend data over quarters- Some jurisdictions may be able to get and report preliminary

burden estimates

Jurisdiction-driven definitions will outperform national definitions- Local flexibility enhances quality and utility by accounting for large

variance in text entries and coding

National guidance- National definition will provide a good starting place- Guidance to encourage common conceptual definition (eg no

withdrawaldetox) and learn from previous work

Rx Summit wwwNationalRxDrugAbuseSummitorg

Our approach

Non-fatal overdoses

Emergency Department

Near real-time ED collection (ie

syndromic ESSENCE)

Case-level or aggregate data shared

through ESSENCE (BioSense) or directly

with CDC

DischargeBilling Data

Case-level or aggregate data shared

directly with CDC

Emergency Medical Services

Case-level or aggregate data shared

directly with CDC

Includes breakdown by

sex age group and county of residence

Raceethnicity is optional

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency Department Data

Two sources- Near real-time syndromic data (visit information within 24-48 hours)- Lagged hospital billing or claims data (usually within 3-4 weeks)

Different variables used- Discharge diagnosis codes (eg ICD-10-CM) ndash available in billing

data and sometimes in syndromic- Free text fields (eg chief complaint provided by Doctor) ndash

available only in syndromic

Rx Summit wwwNationalRxDrugAbuseSummitorg

Case definitions for suspected overdose

If syndromic- Uses both discharge codes (ie ICD-9-CM ICD-10-CM and

SNOMED) and free text fields such as chief complaint or triage notes

- Free text searches use common terms slang and misspellings (eg herion instead of heroin)

If hospital billing or claimshellip- Uses only discharge codes (ie ICD-9-CM ICD-10-CM and

SNOMED)

Discharge codes use are for acute unintentional or undetermined drug poisoning (eg T401X1A in ICD-10-CM) and may also include some substance useabuse codes (ie F11 in ICD-10-CM)

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency medical services data

Capture potential EMS transports to EDs- Excludes instances where individual is pronounced deceased on

the scene inter-facility transports and when EMTs provide no ldquotreatmentrdquo (eg patient refused or required no treatment or transport)

Different variables used- Chief Complaint Secondary complaint- Narrative- Provider Impression- ICD-1O-CM codes- Medication administered (ie Naloxone)- Response to medication administered (ie awake following

Naloxone administration)

Rx Summit wwwNationalRxDrugAbuseSummitorg

Challenges in EMS data

Transition to newer versions of NEMSIS- Some states working in up to three versions (v221 v334 amp

v340)

Different case definitions in different versions

Missing data feeds

Not all EMS agencies share data

Varying time frame in when data is received- lt24 hours to 6 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Data submission process

Rx Summit wwwNationalRxDrugAbuseSummitorg

Sample quality control report

ObsSTATE YEAR QUARTER ERROR_TEXTTOTAL ED VISITS (GENDER)

TOTAL ED VISITS (AGE)

1XX 2017 1 ED Visits mismatch 98287 98309

2XX 2017 2 ED Visits mismatch 98195 98230

3XX 2017 3 ED Visits mismatch 99167 99205

Rx Summit wwwNationalRxDrugAbuseSummitorg

Sample site report

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results All drug (11 sites)

0

10

20

30

40

50

60

70

80

90

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d al

l dru

g ov

erdo

se ra

tes

by

100

00 E

D v

isits

Quarter year

-2000

-1000

000

1000

2000

3000

4000

5000

6000

7000

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Opioid (11 sites)

0

5

10

15

20

25

30

35

40

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Heroin (11 sites)

0

5

10

15

20

25

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-15

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

Annual percentage changes (11 sites)

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Chart1

All drug
Heroin
Opioid
889150252325
302341597796
208009807928
1075831326045
476222826087
283004552352
167997701832
215786123488
271305063812

table with overall

table with overall

All drug
Suspected all drug overdose rates by 10000 ED visits

Sheet1

All drug

table by sex

Opioid
Quarter year
Suspected opioid overdose rates by 10000 ED visits

table by age

Opioid

table by state

Heroin
Quarter year
Suspected opioid overdose rates by 10000 ED visits
Heroin
All drug
Heroin
Opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Summary

Stable increases for all drug and heroin from Q1 2016 to Q3 2017- Opioid had stable increases from Q3 2016 to Q2 2017

Moderate decreases from Q2 to Q3 2017- 9 for all drug 9 for opioid and 12 for heroin

Annual percentage changes were above 15 increases- Q1 to Q1 89 all drug 30 heroin amp 21 opioid- Q2 to Q2 108 all drug 48 heroin amp 28 opioid- Q3 to Q3 17 all drug 22 heroin amp 27 opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency department data dissemination efforts

ldquoOpioid Overdoses Treated in Emergency Departmentsrdquo -httpswwwcdcgovvitalsignsopioid-overdosesindexhtml

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose

Reporting System

Presenter Julie OrsquoDonnell PhD MPHEpidemiologist

Centers for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Alana Vivolo-Kantor R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Julie OrsquoDonnell PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Increase in deaths outpaces increase in use

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid

overdose

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid overdose surveillance

Track specific substances contributing to overdose deaths

Detect newly-emerging substances involved in overdose

Determine risk factors circumstances associated with fatal overdose

Assess common drug combinations Provide more timely data on overdose deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

State Unintentional Drug Overdose Reporting System (SUDORS)

Death certificates

Medical examiner

coroner reportsToxicology

reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data submitted bi-annually

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

1 Data entry started

2 Data entry finished

1 Data entry started

2 Data entry finished

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS leverages National Violent Death Reporting System (NVDRS) platform

- Basic descriptors- Compare across demographics

- Recent release from institution- Overdose location - Survival time

- Mental health diagnoses- Substance abuse treatment history

- Substances present- Substances contributing to death

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Maine 1941 -1273 225 278 1523 -201 3951 -692 257 -813 2945 981 793 656 -299 -2255 3199 2197
Massachusetts na na na na na na 1561 -157 -848 -1148 311 1897 553 -31 -13 -1632 456 2146
New Hampshire 511 1514 -1438 -832 2583 -961 318 64 -433 -1791 2967 -876 825 -184 -1002 -2016 3363 -17
Pennsylvania na na 869 -102 1211 -116 na na 2979 1751 2589 -594 na na 2601 1534 2735 -735
Rhode Island na na 735 -790 1002 -1594 na na 28 454 544 -1191 na na 121 1057 566 -3262
West Virginia -1596 875 2978 -1543 409 -1651 -367 995 4331 -1664 402 -2377 -769 1847 4571 -1584 -199 -3022
Kentucky -102 1242 -1707 2211 1092 -1468 1095 5192 -2694 4045 352 -2002 -043 5541 -3206 5012 -408 -1624
New Mexico 2932 283 521 -078 445 -716 255 -1298 2611 151 -501 -1093 -487 -3061 3227 987 -1715 323
Missouri 068 -304 754 028 114 421 292 827 477 -177 954 767 -046 1839 096 -512 966 125
Ohio na na 107 1216 1596 -1865 na na 2274 2567 2167 -3194 na na 2182 2254 2086 -3348
Wisconsin -229 1388 861 2928 888 931 -948 986 1712 6728 322 314 -1457 91 983 9621 196 668
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 1514 2112 1966 2017 1853 2398 2634
Massachusetts 7036 8133 8006 7327 6486 6687 7956
New Hampshire 3806 3927 4179 3998 3282 4255 3882
Pennsylvania na na 1265 1641 1929 2428 2284
Rhode Island na na 1498 154 161 1698 1496
West Virginia 2258 2176 2392 3428 2857 2972 2266
Kentucky 2095 2325 3532 258 3624 3752 3001
New Mexico 1927 1976 1719 2168 2201 2091 1862
Missouri 1472 1515 1641 1719 1688 185 1991
Ohio na na 236 2897 3641 443 3015
Wisconsin 664 601 66 773 1294 1336 1377
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 502 9 959 931 721 952 1161
Massachusetts 4035 4258 4126 359 3004 3141 3815
New Hampshire 2514 2721 2671 2403 1919 2564 2128
Pennsylvania na na 1013 1277 1473 1876 1738
Rhode Island na na 803 812 898 949 639
West Virginia 1496 1381 1636 2384 2006 1966 1372
Kentucky 1772 1764 2741 1863 2796 2682 2247
New Mexico 902 858 595 787 865 717 74
Missouri 1002 997 118 1192 1131 124 1255
Ohio na na 1804 2198 2693 3254 2165
Wisconsin 286 244 267 293 575 586 625
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 5609 6697 5845 5976 6142 7078 6936
Massachusetts na na na na na na na
New Hampshire 5678 5968 6872 5883 5394 6787 6135
Pennsylvania na na 8374 9102 9010 10100 9983
Rhode Island na na 3567 3829 3527 3880 3262
West Virginia 4628 3889 4229 5489 4642 4832 4034
Kentucky 6756 6687 7517 6234 7613 8444 7205
New Mexico 5291 6842 7036 7402 7345 7672 7123
Missouri 3213 3235 3137 3373 3383 3421 3565
Ohio na na 8696 8789 9859 11432 9300
Wisconsin 2724 2661 3031 3291 4255 4633 5064
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
15 to 24
25 to 34
35 to 54
55 and up
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Male -140 7355 827 901 1286 -927 742 -758 1157 1241 1306 -829 146 301 1082 1242 1306 -1249
Female 841 5151 103 733 1257 -1521 659 -922 533 1204 1494 -1014 -132 1299 229 1331 1617 -1214
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 4888 4820 8365 9057 9873 11142 10110
Female 3201 3470 5257 5312 5701 6418 5442
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 3611 3879 3585 40 4496 5083 4662
Female 159 1695 1538 162 1816 2087 1875
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 2295 2328 2399 2658 2988 3379 2957
Female 839 828 936 957 1085 126 1107
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017 q1 q2 q3
All drug 3948 4061 6589 6894 7458 8430 7696 889150252325 1075831326045 167997701832
Heroin 1452 1472 1571 1681 1891 2173 191 302341597796 476222826087 215786123488
Opioid 2447 2636 2429 2636 2956 3382 3088 208009807928 283004552352 271305063812
Q12016-Q12017 Q22016-Q22017 Q32016-Q32017
All drug 889150252325 1075831326045 167997701832
Heroin 302341597796 476222826087 215786123488
Opioid 208009807928 283004552352 271305063812
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Heroin 136 674 701 1251 1486 -1209
Opioid 77 -785 853 1212 1442 -868
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Heroin 1452 1472 1571 1681 1891 2173 191
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Heroin 1452 1472 1571 1681 1891 2173 191
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Opioid 77 -785 853 1212 1442 -868
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Heroin 136 674 701 1251 1486 -1209
Q12016-Q12017 Q12016-Q12017 Q12016-Q12017
Q22016-Q22017 Q22016-Q22017 Q22016-Q22017
Q32016-Q32017 Q32016-Q32017 Q32016-Q32017
Column1 Any opioid Natural and semi-synthetic opioid analgesic Methadone Synthetic opioid analgesic excluding methadone Heroin
1999 1 03 03 07
21 1 04 03 07
2001 24 12 05 03 06
32 15 08 04 07
2003 35 17 1 05 07
39 18 13 06 06
2005 43 19 15 06 07
51 23 18 09 07
2007 54 27 18 07 08
57 3 16 08 1
2009 59 31 15 1 11
62 35 15 1 1
2011 66 37 14 08 14
67 35 12 08 19
2013 74 35 11 1 27
86 38 11 18 34
2015 104 39 1 31 41
133 44 1 62 49
1999 1999 1999 1999
1 04 03 07
2001 2001 2001 2001
15 08 04 07
2003 2003 2003 2003
18 13 06 06
2005 2005 2005 2005
23 18 09 07
2007 2007 2007 2007
3 16 08 1
2009 2009 2009 2009
35 15 1 1
2011 2011 2011 2011
35 12 08 19
2013 2013 2013 2013
38 11 18 34
2015 2015 2015 2015
44 1 62 49
Page 8: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

Opioid Overdoses Treated in Emergency Departments

Vivolo-Kantor AM Seth P Gladden RM Mattson CL Baldwin GT Kite-Powell A Coletta MA Vital Signs Trends in Emergency Department Visits for Suspected Opioid Overdoses mdash United States July 2016ndashSeptember 2017(httpswwwcdcgovmmwrvolumes67wrmm6709e1htm) MMWR Morb Mortal Wkly Rep201867

Rx Summit wwwNationalRxDrugAbuseSummitorg

Vivolo-Kantor AM Seth P Gladden RM Mattson CL Baldwin GT Kite-Powell A Coletta MA Vital Signs Trends in Emergency Department Visits for Suspected Opioid Overdoses mdash United States July 2016ndashSeptember 2017(httpswwwcdcgovmmwrvolumes67wrmm6709e1htm) MMWR Morb Mortal Wkly Rep201867

Rx Summit wwwNationalRxDrugAbuseSummitorg

2000 Rapid Increase in Drug Overdose Death Rates by County

SOURCE NCHS Data Visualization Gallery

Rx Summit wwwNationalRxDrugAbuseSummitorgSOURCE NCHS Data Visualization Gallery

2005 Rapid Increase in Drug Overdose Death Rates by County

Rx Summit wwwNationalRxDrugAbuseSummitorgSOURCE NCHS Data Visualization Gallery

2010 Rapid Increase in Drug Overdose Death Rates by County

Rx Summit wwwNationalRxDrugAbuseSummitorgSOURCE NCHS Data Visualization Gallery

2016 Rapid Increase in Drug Overdose Death Rates by County

Rx Summit wwwNationalRxDrugAbuseSummitorg

RISE IN OPIOID DEATHS

Overlapping Entangled but Distinct Epidemics

Natural and semi-synthetic opioidslike oxycodone or hydrocodone

Methadone

Heroin

SOURCE National Vital Statistics System Mortality File

Dea

ths

per 1

000

00 p

opul

atio

n

Chart1

Synthetic opioidslike fentanyl
3 Waves
Almost 351630 people have died from an opioid overdose during 1999-2016
Natural and semi-synthetic opioid analgesic
Methadone
Synthetic opioid analgesic excluding methadone
Heroin
1
03
03
07
12
05
03
06
17
1
05
07
19
15
06
07
27
18
07
08
31
15
1
11
37
14
08
14
35
11
1
27
39
1
31
41

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

CDCrsquos Pillars on Opioids Conducting surveillance and research

Building state local and tribal prevention efforts

Supporting healthcare providers and health systems

Partnering with public safety officials

Encouraging consumers to make safe choices about opioids raising awareness about prescription opioid misuse and overdose

Rx Summit wwwNationalRxDrugAbuseSummitorg

Enhanced State Opioid Overdose Surveillance (ESOOS) 12 states funded in September 2016 20 additional states and the

District of Columbia funded in September 2017 (through September 2019)

Strategy One Increase timeliness of non-fatal opioid overdose reporting- Use syndromic surveillance to establish an early warning system to

detect sharp increases or decreases in non-fatal opioid overdoses - Three indicators suspected all-drug opioid and heroin

Alaska California Connecticut Delaware DC Florida Georgia Illinois Indiana Kentucky Louisiana Maine Maryland Massachusetts Michigan Minnesota Missouri Nevada New Hampshire New Jersey New Mexico North Carolina Ohio Oklahoma Pennsylvania Rhode Island Tennessee Utah Vermont Virginia Washington West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

Enhanced State Opioid Overdose Surveillance (ESOOS) Strategy Two Increase timeliness of fatal opioid overdose

reporting- Capture detailed information on toxicology death scene

investigations and other risk factors that may be associated with a fatal overdose

Strategy Three widespread dissemination- Rapidly disseminate surveillance findings to key stakeholders

working to prevent or respond to opioid overdoses

ESOOS program expansion in September 2017- At least 60 for comprehensive toxicology testing for opioid-

involved deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

Funded ESOOS states

Rx Summit wwwNationalRxDrugAbuseSummitorg

Enhanced State Opioid Overdose Surveillance (ESOOS)

Nonfatal Opioid Overdoses Reported

Quarterly

Emergency Department Visits EMS Transports

Fatal Opioid Overdoses Reported within 8 months

of death

Death CertificatesMEC reports

Toxicology reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

Next Two Presentationshellip

The Utilization of Emergency Department Syndromic Surveillance and Emergency Medical Services Data to Monitor Nonfatal Opioid Overdoses ndash Dr Alana Vivolo-Kantor

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System ndash Dr Julie OrsquoDonnell

Rx Summit wwwNationalRxDrugAbuseSummitorg

The utilization of emergency department syndromic surveillance

and emergency medical services data to monitor nonfatal opioid

overdosesPresenter Alana Vivolo-Kantor PhD

Behavioral ScientistCenters for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Julie OrsquoDonnell R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Alana Vivolo-Kantor PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Why Emergency Department and Emergency Medical Service Data for Surveillance

Need- Identify areas experiencing rapid increases in opioid overdoses to

inform responses- More quickly identify promising practices to reduce opioid overdoses

Proven utility to public health and scalable- Local jurisdictions already using it to track and respond to drug

overdoses- Findings from Epi-Aid investigations and collaborative work with states- Leverage existing state and national resources (BioSenseESSENCE)

Action at local and national level- Track quarterly trends across the nation to inform national policy- Improve more rapid local and state public health response

Rx Summit wwwNationalRxDrugAbuseSummitorg

Our Philosophy

Focus on detecting change- Pushing system by looking at trend data over quarters- Some jurisdictions may be able to get and report preliminary

burden estimates

Jurisdiction-driven definitions will outperform national definitions- Local flexibility enhances quality and utility by accounting for large

variance in text entries and coding

National guidance- National definition will provide a good starting place- Guidance to encourage common conceptual definition (eg no

withdrawaldetox) and learn from previous work

Rx Summit wwwNationalRxDrugAbuseSummitorg

Our approach

Non-fatal overdoses

Emergency Department

Near real-time ED collection (ie

syndromic ESSENCE)

Case-level or aggregate data shared

through ESSENCE (BioSense) or directly

with CDC

DischargeBilling Data

Case-level or aggregate data shared

directly with CDC

Emergency Medical Services

Case-level or aggregate data shared

directly with CDC

Includes breakdown by

sex age group and county of residence

Raceethnicity is optional

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency Department Data

Two sources- Near real-time syndromic data (visit information within 24-48 hours)- Lagged hospital billing or claims data (usually within 3-4 weeks)

Different variables used- Discharge diagnosis codes (eg ICD-10-CM) ndash available in billing

data and sometimes in syndromic- Free text fields (eg chief complaint provided by Doctor) ndash

available only in syndromic

Rx Summit wwwNationalRxDrugAbuseSummitorg

Case definitions for suspected overdose

If syndromic- Uses both discharge codes (ie ICD-9-CM ICD-10-CM and

SNOMED) and free text fields such as chief complaint or triage notes

- Free text searches use common terms slang and misspellings (eg herion instead of heroin)

If hospital billing or claimshellip- Uses only discharge codes (ie ICD-9-CM ICD-10-CM and

SNOMED)

Discharge codes use are for acute unintentional or undetermined drug poisoning (eg T401X1A in ICD-10-CM) and may also include some substance useabuse codes (ie F11 in ICD-10-CM)

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency medical services data

Capture potential EMS transports to EDs- Excludes instances where individual is pronounced deceased on

the scene inter-facility transports and when EMTs provide no ldquotreatmentrdquo (eg patient refused or required no treatment or transport)

Different variables used- Chief Complaint Secondary complaint- Narrative- Provider Impression- ICD-1O-CM codes- Medication administered (ie Naloxone)- Response to medication administered (ie awake following

Naloxone administration)

Rx Summit wwwNationalRxDrugAbuseSummitorg

Challenges in EMS data

Transition to newer versions of NEMSIS- Some states working in up to three versions (v221 v334 amp

v340)

Different case definitions in different versions

Missing data feeds

Not all EMS agencies share data

Varying time frame in when data is received- lt24 hours to 6 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Data submission process

Rx Summit wwwNationalRxDrugAbuseSummitorg

Sample quality control report

ObsSTATE YEAR QUARTER ERROR_TEXTTOTAL ED VISITS (GENDER)

TOTAL ED VISITS (AGE)

1XX 2017 1 ED Visits mismatch 98287 98309

2XX 2017 2 ED Visits mismatch 98195 98230

3XX 2017 3 ED Visits mismatch 99167 99205

Rx Summit wwwNationalRxDrugAbuseSummitorg

Sample site report

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results All drug (11 sites)

0

10

20

30

40

50

60

70

80

90

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d al

l dru

g ov

erdo

se ra

tes

by

100

00 E

D v

isits

Quarter year

-2000

-1000

000

1000

2000

3000

4000

5000

6000

7000

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Opioid (11 sites)

0

5

10

15

20

25

30

35

40

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Heroin (11 sites)

0

5

10

15

20

25

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-15

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

Annual percentage changes (11 sites)

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Chart1

All drug
Heroin
Opioid
889150252325
302341597796
208009807928
1075831326045
476222826087
283004552352
167997701832
215786123488
271305063812

table with overall

table with overall

All drug
Suspected all drug overdose rates by 10000 ED visits

Sheet1

All drug

table by sex

Opioid
Quarter year
Suspected opioid overdose rates by 10000 ED visits

table by age

Opioid

table by state

Heroin
Quarter year
Suspected opioid overdose rates by 10000 ED visits
Heroin
All drug
Heroin
Opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Summary

Stable increases for all drug and heroin from Q1 2016 to Q3 2017- Opioid had stable increases from Q3 2016 to Q2 2017

Moderate decreases from Q2 to Q3 2017- 9 for all drug 9 for opioid and 12 for heroin

Annual percentage changes were above 15 increases- Q1 to Q1 89 all drug 30 heroin amp 21 opioid- Q2 to Q2 108 all drug 48 heroin amp 28 opioid- Q3 to Q3 17 all drug 22 heroin amp 27 opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency department data dissemination efforts

ldquoOpioid Overdoses Treated in Emergency Departmentsrdquo -httpswwwcdcgovvitalsignsopioid-overdosesindexhtml

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose

Reporting System

Presenter Julie OrsquoDonnell PhD MPHEpidemiologist

Centers for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Alana Vivolo-Kantor R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Julie OrsquoDonnell PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Increase in deaths outpaces increase in use

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid

overdose

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid overdose surveillance

Track specific substances contributing to overdose deaths

Detect newly-emerging substances involved in overdose

Determine risk factors circumstances associated with fatal overdose

Assess common drug combinations Provide more timely data on overdose deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

State Unintentional Drug Overdose Reporting System (SUDORS)

Death certificates

Medical examiner

coroner reportsToxicology

reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data submitted bi-annually

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

1 Data entry started

2 Data entry finished

1 Data entry started

2 Data entry finished

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS leverages National Violent Death Reporting System (NVDRS) platform

- Basic descriptors- Compare across demographics

- Recent release from institution- Overdose location - Survival time

- Mental health diagnoses- Substance abuse treatment history

- Substances present- Substances contributing to death

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Maine 1941 -1273 225 278 1523 -201 3951 -692 257 -813 2945 981 793 656 -299 -2255 3199 2197
Massachusetts na na na na na na 1561 -157 -848 -1148 311 1897 553 -31 -13 -1632 456 2146
New Hampshire 511 1514 -1438 -832 2583 -961 318 64 -433 -1791 2967 -876 825 -184 -1002 -2016 3363 -17
Pennsylvania na na 869 -102 1211 -116 na na 2979 1751 2589 -594 na na 2601 1534 2735 -735
Rhode Island na na 735 -790 1002 -1594 na na 28 454 544 -1191 na na 121 1057 566 -3262
West Virginia -1596 875 2978 -1543 409 -1651 -367 995 4331 -1664 402 -2377 -769 1847 4571 -1584 -199 -3022
Kentucky -102 1242 -1707 2211 1092 -1468 1095 5192 -2694 4045 352 -2002 -043 5541 -3206 5012 -408 -1624
New Mexico 2932 283 521 -078 445 -716 255 -1298 2611 151 -501 -1093 -487 -3061 3227 987 -1715 323
Missouri 068 -304 754 028 114 421 292 827 477 -177 954 767 -046 1839 096 -512 966 125
Ohio na na 107 1216 1596 -1865 na na 2274 2567 2167 -3194 na na 2182 2254 2086 -3348
Wisconsin -229 1388 861 2928 888 931 -948 986 1712 6728 322 314 -1457 91 983 9621 196 668
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 1514 2112 1966 2017 1853 2398 2634
Massachusetts 7036 8133 8006 7327 6486 6687 7956
New Hampshire 3806 3927 4179 3998 3282 4255 3882
Pennsylvania na na 1265 1641 1929 2428 2284
Rhode Island na na 1498 154 161 1698 1496
West Virginia 2258 2176 2392 3428 2857 2972 2266
Kentucky 2095 2325 3532 258 3624 3752 3001
New Mexico 1927 1976 1719 2168 2201 2091 1862
Missouri 1472 1515 1641 1719 1688 185 1991
Ohio na na 236 2897 3641 443 3015
Wisconsin 664 601 66 773 1294 1336 1377
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 502 9 959 931 721 952 1161
Massachusetts 4035 4258 4126 359 3004 3141 3815
New Hampshire 2514 2721 2671 2403 1919 2564 2128
Pennsylvania na na 1013 1277 1473 1876 1738
Rhode Island na na 803 812 898 949 639
West Virginia 1496 1381 1636 2384 2006 1966 1372
Kentucky 1772 1764 2741 1863 2796 2682 2247
New Mexico 902 858 595 787 865 717 74
Missouri 1002 997 118 1192 1131 124 1255
Ohio na na 1804 2198 2693 3254 2165
Wisconsin 286 244 267 293 575 586 625
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 5609 6697 5845 5976 6142 7078 6936
Massachusetts na na na na na na na
New Hampshire 5678 5968 6872 5883 5394 6787 6135
Pennsylvania na na 8374 9102 9010 10100 9983
Rhode Island na na 3567 3829 3527 3880 3262
West Virginia 4628 3889 4229 5489 4642 4832 4034
Kentucky 6756 6687 7517 6234 7613 8444 7205
New Mexico 5291 6842 7036 7402 7345 7672 7123
Missouri 3213 3235 3137 3373 3383 3421 3565
Ohio na na 8696 8789 9859 11432 9300
Wisconsin 2724 2661 3031 3291 4255 4633 5064
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
15 to 24
25 to 34
35 to 54
55 and up
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Male -140 7355 827 901 1286 -927 742 -758 1157 1241 1306 -829 146 301 1082 1242 1306 -1249
Female 841 5151 103 733 1257 -1521 659 -922 533 1204 1494 -1014 -132 1299 229 1331 1617 -1214
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 4888 4820 8365 9057 9873 11142 10110
Female 3201 3470 5257 5312 5701 6418 5442
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 3611 3879 3585 40 4496 5083 4662
Female 159 1695 1538 162 1816 2087 1875
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 2295 2328 2399 2658 2988 3379 2957
Female 839 828 936 957 1085 126 1107
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017 q1 q2 q3
All drug 3948 4061 6589 6894 7458 8430 7696 889150252325 1075831326045 167997701832
Heroin 1452 1472 1571 1681 1891 2173 191 302341597796 476222826087 215786123488
Opioid 2447 2636 2429 2636 2956 3382 3088 208009807928 283004552352 271305063812
Q12016-Q12017 Q22016-Q22017 Q32016-Q32017
All drug 889150252325 1075831326045 167997701832
Heroin 302341597796 476222826087 215786123488
Opioid 208009807928 283004552352 271305063812
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Heroin 136 674 701 1251 1486 -1209
Opioid 77 -785 853 1212 1442 -868
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Heroin 1452 1472 1571 1681 1891 2173 191
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Heroin 1452 1472 1571 1681 1891 2173 191
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Opioid 77 -785 853 1212 1442 -868
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Heroin 136 674 701 1251 1486 -1209
Q12016-Q12017 Q12016-Q12017 Q12016-Q12017
Q22016-Q22017 Q22016-Q22017 Q22016-Q22017
Q32016-Q32017 Q32016-Q32017 Q32016-Q32017
Column1 Any opioid Natural and semi-synthetic opioid analgesic Methadone Synthetic opioid analgesic excluding methadone Heroin
1999 1 03 03 07
21 1 04 03 07
2001 24 12 05 03 06
32 15 08 04 07
2003 35 17 1 05 07
39 18 13 06 06
2005 43 19 15 06 07
51 23 18 09 07
2007 54 27 18 07 08
57 3 16 08 1
2009 59 31 15 1 11
62 35 15 1 1
2011 66 37 14 08 14
67 35 12 08 19
2013 74 35 11 1 27
86 38 11 18 34
2015 104 39 1 31 41
133 44 1 62 49
1999 1999 1999 1999
1 04 03 07
2001 2001 2001 2001
15 08 04 07
2003 2003 2003 2003
18 13 06 06
2005 2005 2005 2005
23 18 09 07
2007 2007 2007 2007
3 16 08 1
2009 2009 2009 2009
35 15 1 1
2011 2011 2011 2011
35 12 08 19
2013 2013 2013 2013
38 11 18 34
2015 2015 2015 2015
44 1 62 49
Page 9: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

Vivolo-Kantor AM Seth P Gladden RM Mattson CL Baldwin GT Kite-Powell A Coletta MA Vital Signs Trends in Emergency Department Visits for Suspected Opioid Overdoses mdash United States July 2016ndashSeptember 2017(httpswwwcdcgovmmwrvolumes67wrmm6709e1htm) MMWR Morb Mortal Wkly Rep201867

Rx Summit wwwNationalRxDrugAbuseSummitorg

2000 Rapid Increase in Drug Overdose Death Rates by County

SOURCE NCHS Data Visualization Gallery

Rx Summit wwwNationalRxDrugAbuseSummitorgSOURCE NCHS Data Visualization Gallery

2005 Rapid Increase in Drug Overdose Death Rates by County

Rx Summit wwwNationalRxDrugAbuseSummitorgSOURCE NCHS Data Visualization Gallery

2010 Rapid Increase in Drug Overdose Death Rates by County

Rx Summit wwwNationalRxDrugAbuseSummitorgSOURCE NCHS Data Visualization Gallery

2016 Rapid Increase in Drug Overdose Death Rates by County

Rx Summit wwwNationalRxDrugAbuseSummitorg

RISE IN OPIOID DEATHS

Overlapping Entangled but Distinct Epidemics

Natural and semi-synthetic opioidslike oxycodone or hydrocodone

Methadone

Heroin

SOURCE National Vital Statistics System Mortality File

Dea

ths

per 1

000

00 p

opul

atio

n

Chart1

Synthetic opioidslike fentanyl
3 Waves
Almost 351630 people have died from an opioid overdose during 1999-2016
Natural and semi-synthetic opioid analgesic
Methadone
Synthetic opioid analgesic excluding methadone
Heroin
1
03
03
07
12
05
03
06
17
1
05
07
19
15
06
07
27
18
07
08
31
15
1
11
37
14
08
14
35
11
1
27
39
1
31
41

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

CDCrsquos Pillars on Opioids Conducting surveillance and research

Building state local and tribal prevention efforts

Supporting healthcare providers and health systems

Partnering with public safety officials

Encouraging consumers to make safe choices about opioids raising awareness about prescription opioid misuse and overdose

Rx Summit wwwNationalRxDrugAbuseSummitorg

Enhanced State Opioid Overdose Surveillance (ESOOS) 12 states funded in September 2016 20 additional states and the

District of Columbia funded in September 2017 (through September 2019)

Strategy One Increase timeliness of non-fatal opioid overdose reporting- Use syndromic surveillance to establish an early warning system to

detect sharp increases or decreases in non-fatal opioid overdoses - Three indicators suspected all-drug opioid and heroin

Alaska California Connecticut Delaware DC Florida Georgia Illinois Indiana Kentucky Louisiana Maine Maryland Massachusetts Michigan Minnesota Missouri Nevada New Hampshire New Jersey New Mexico North Carolina Ohio Oklahoma Pennsylvania Rhode Island Tennessee Utah Vermont Virginia Washington West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

Enhanced State Opioid Overdose Surveillance (ESOOS) Strategy Two Increase timeliness of fatal opioid overdose

reporting- Capture detailed information on toxicology death scene

investigations and other risk factors that may be associated with a fatal overdose

Strategy Three widespread dissemination- Rapidly disseminate surveillance findings to key stakeholders

working to prevent or respond to opioid overdoses

ESOOS program expansion in September 2017- At least 60 for comprehensive toxicology testing for opioid-

involved deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

Funded ESOOS states

Rx Summit wwwNationalRxDrugAbuseSummitorg

Enhanced State Opioid Overdose Surveillance (ESOOS)

Nonfatal Opioid Overdoses Reported

Quarterly

Emergency Department Visits EMS Transports

Fatal Opioid Overdoses Reported within 8 months

of death

Death CertificatesMEC reports

Toxicology reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

Next Two Presentationshellip

The Utilization of Emergency Department Syndromic Surveillance and Emergency Medical Services Data to Monitor Nonfatal Opioid Overdoses ndash Dr Alana Vivolo-Kantor

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System ndash Dr Julie OrsquoDonnell

Rx Summit wwwNationalRxDrugAbuseSummitorg

The utilization of emergency department syndromic surveillance

and emergency medical services data to monitor nonfatal opioid

overdosesPresenter Alana Vivolo-Kantor PhD

Behavioral ScientistCenters for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Julie OrsquoDonnell R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Alana Vivolo-Kantor PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Why Emergency Department and Emergency Medical Service Data for Surveillance

Need- Identify areas experiencing rapid increases in opioid overdoses to

inform responses- More quickly identify promising practices to reduce opioid overdoses

Proven utility to public health and scalable- Local jurisdictions already using it to track and respond to drug

overdoses- Findings from Epi-Aid investigations and collaborative work with states- Leverage existing state and national resources (BioSenseESSENCE)

Action at local and national level- Track quarterly trends across the nation to inform national policy- Improve more rapid local and state public health response

Rx Summit wwwNationalRxDrugAbuseSummitorg

Our Philosophy

Focus on detecting change- Pushing system by looking at trend data over quarters- Some jurisdictions may be able to get and report preliminary

burden estimates

Jurisdiction-driven definitions will outperform national definitions- Local flexibility enhances quality and utility by accounting for large

variance in text entries and coding

National guidance- National definition will provide a good starting place- Guidance to encourage common conceptual definition (eg no

withdrawaldetox) and learn from previous work

Rx Summit wwwNationalRxDrugAbuseSummitorg

Our approach

Non-fatal overdoses

Emergency Department

Near real-time ED collection (ie

syndromic ESSENCE)

Case-level or aggregate data shared

through ESSENCE (BioSense) or directly

with CDC

DischargeBilling Data

Case-level or aggregate data shared

directly with CDC

Emergency Medical Services

Case-level or aggregate data shared

directly with CDC

Includes breakdown by

sex age group and county of residence

Raceethnicity is optional

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency Department Data

Two sources- Near real-time syndromic data (visit information within 24-48 hours)- Lagged hospital billing or claims data (usually within 3-4 weeks)

Different variables used- Discharge diagnosis codes (eg ICD-10-CM) ndash available in billing

data and sometimes in syndromic- Free text fields (eg chief complaint provided by Doctor) ndash

available only in syndromic

Rx Summit wwwNationalRxDrugAbuseSummitorg

Case definitions for suspected overdose

If syndromic- Uses both discharge codes (ie ICD-9-CM ICD-10-CM and

SNOMED) and free text fields such as chief complaint or triage notes

- Free text searches use common terms slang and misspellings (eg herion instead of heroin)

If hospital billing or claimshellip- Uses only discharge codes (ie ICD-9-CM ICD-10-CM and

SNOMED)

Discharge codes use are for acute unintentional or undetermined drug poisoning (eg T401X1A in ICD-10-CM) and may also include some substance useabuse codes (ie F11 in ICD-10-CM)

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency medical services data

Capture potential EMS transports to EDs- Excludes instances where individual is pronounced deceased on

the scene inter-facility transports and when EMTs provide no ldquotreatmentrdquo (eg patient refused or required no treatment or transport)

Different variables used- Chief Complaint Secondary complaint- Narrative- Provider Impression- ICD-1O-CM codes- Medication administered (ie Naloxone)- Response to medication administered (ie awake following

Naloxone administration)

Rx Summit wwwNationalRxDrugAbuseSummitorg

Challenges in EMS data

Transition to newer versions of NEMSIS- Some states working in up to three versions (v221 v334 amp

v340)

Different case definitions in different versions

Missing data feeds

Not all EMS agencies share data

Varying time frame in when data is received- lt24 hours to 6 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Data submission process

Rx Summit wwwNationalRxDrugAbuseSummitorg

Sample quality control report

ObsSTATE YEAR QUARTER ERROR_TEXTTOTAL ED VISITS (GENDER)

TOTAL ED VISITS (AGE)

1XX 2017 1 ED Visits mismatch 98287 98309

2XX 2017 2 ED Visits mismatch 98195 98230

3XX 2017 3 ED Visits mismatch 99167 99205

Rx Summit wwwNationalRxDrugAbuseSummitorg

Sample site report

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results All drug (11 sites)

0

10

20

30

40

50

60

70

80

90

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d al

l dru

g ov

erdo

se ra

tes

by

100

00 E

D v

isits

Quarter year

-2000

-1000

000

1000

2000

3000

4000

5000

6000

7000

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Opioid (11 sites)

0

5

10

15

20

25

30

35

40

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Heroin (11 sites)

0

5

10

15

20

25

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-15

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

Annual percentage changes (11 sites)

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Chart1

All drug
Heroin
Opioid
889150252325
302341597796
208009807928
1075831326045
476222826087
283004552352
167997701832
215786123488
271305063812

table with overall

table with overall

All drug
Suspected all drug overdose rates by 10000 ED visits

Sheet1

All drug

table by sex

Opioid
Quarter year
Suspected opioid overdose rates by 10000 ED visits

table by age

Opioid

table by state

Heroin
Quarter year
Suspected opioid overdose rates by 10000 ED visits
Heroin
All drug
Heroin
Opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Summary

Stable increases for all drug and heroin from Q1 2016 to Q3 2017- Opioid had stable increases from Q3 2016 to Q2 2017

Moderate decreases from Q2 to Q3 2017- 9 for all drug 9 for opioid and 12 for heroin

Annual percentage changes were above 15 increases- Q1 to Q1 89 all drug 30 heroin amp 21 opioid- Q2 to Q2 108 all drug 48 heroin amp 28 opioid- Q3 to Q3 17 all drug 22 heroin amp 27 opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency department data dissemination efforts

ldquoOpioid Overdoses Treated in Emergency Departmentsrdquo -httpswwwcdcgovvitalsignsopioid-overdosesindexhtml

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose

Reporting System

Presenter Julie OrsquoDonnell PhD MPHEpidemiologist

Centers for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Alana Vivolo-Kantor R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Julie OrsquoDonnell PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Increase in deaths outpaces increase in use

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid

overdose

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid overdose surveillance

Track specific substances contributing to overdose deaths

Detect newly-emerging substances involved in overdose

Determine risk factors circumstances associated with fatal overdose

Assess common drug combinations Provide more timely data on overdose deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

State Unintentional Drug Overdose Reporting System (SUDORS)

Death certificates

Medical examiner

coroner reportsToxicology

reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data submitted bi-annually

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

1 Data entry started

2 Data entry finished

1 Data entry started

2 Data entry finished

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS leverages National Violent Death Reporting System (NVDRS) platform

- Basic descriptors- Compare across demographics

- Recent release from institution- Overdose location - Survival time

- Mental health diagnoses- Substance abuse treatment history

- Substances present- Substances contributing to death

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Maine 1941 -1273 225 278 1523 -201 3951 -692 257 -813 2945 981 793 656 -299 -2255 3199 2197
Massachusetts na na na na na na 1561 -157 -848 -1148 311 1897 553 -31 -13 -1632 456 2146
New Hampshire 511 1514 -1438 -832 2583 -961 318 64 -433 -1791 2967 -876 825 -184 -1002 -2016 3363 -17
Pennsylvania na na 869 -102 1211 -116 na na 2979 1751 2589 -594 na na 2601 1534 2735 -735
Rhode Island na na 735 -790 1002 -1594 na na 28 454 544 -1191 na na 121 1057 566 -3262
West Virginia -1596 875 2978 -1543 409 -1651 -367 995 4331 -1664 402 -2377 -769 1847 4571 -1584 -199 -3022
Kentucky -102 1242 -1707 2211 1092 -1468 1095 5192 -2694 4045 352 -2002 -043 5541 -3206 5012 -408 -1624
New Mexico 2932 283 521 -078 445 -716 255 -1298 2611 151 -501 -1093 -487 -3061 3227 987 -1715 323
Missouri 068 -304 754 028 114 421 292 827 477 -177 954 767 -046 1839 096 -512 966 125
Ohio na na 107 1216 1596 -1865 na na 2274 2567 2167 -3194 na na 2182 2254 2086 -3348
Wisconsin -229 1388 861 2928 888 931 -948 986 1712 6728 322 314 -1457 91 983 9621 196 668
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 1514 2112 1966 2017 1853 2398 2634
Massachusetts 7036 8133 8006 7327 6486 6687 7956
New Hampshire 3806 3927 4179 3998 3282 4255 3882
Pennsylvania na na 1265 1641 1929 2428 2284
Rhode Island na na 1498 154 161 1698 1496
West Virginia 2258 2176 2392 3428 2857 2972 2266
Kentucky 2095 2325 3532 258 3624 3752 3001
New Mexico 1927 1976 1719 2168 2201 2091 1862
Missouri 1472 1515 1641 1719 1688 185 1991
Ohio na na 236 2897 3641 443 3015
Wisconsin 664 601 66 773 1294 1336 1377
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 502 9 959 931 721 952 1161
Massachusetts 4035 4258 4126 359 3004 3141 3815
New Hampshire 2514 2721 2671 2403 1919 2564 2128
Pennsylvania na na 1013 1277 1473 1876 1738
Rhode Island na na 803 812 898 949 639
West Virginia 1496 1381 1636 2384 2006 1966 1372
Kentucky 1772 1764 2741 1863 2796 2682 2247
New Mexico 902 858 595 787 865 717 74
Missouri 1002 997 118 1192 1131 124 1255
Ohio na na 1804 2198 2693 3254 2165
Wisconsin 286 244 267 293 575 586 625
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 5609 6697 5845 5976 6142 7078 6936
Massachusetts na na na na na na na
New Hampshire 5678 5968 6872 5883 5394 6787 6135
Pennsylvania na na 8374 9102 9010 10100 9983
Rhode Island na na 3567 3829 3527 3880 3262
West Virginia 4628 3889 4229 5489 4642 4832 4034
Kentucky 6756 6687 7517 6234 7613 8444 7205
New Mexico 5291 6842 7036 7402 7345 7672 7123
Missouri 3213 3235 3137 3373 3383 3421 3565
Ohio na na 8696 8789 9859 11432 9300
Wisconsin 2724 2661 3031 3291 4255 4633 5064
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
15 to 24
25 to 34
35 to 54
55 and up
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Male -140 7355 827 901 1286 -927 742 -758 1157 1241 1306 -829 146 301 1082 1242 1306 -1249
Female 841 5151 103 733 1257 -1521 659 -922 533 1204 1494 -1014 -132 1299 229 1331 1617 -1214
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 4888 4820 8365 9057 9873 11142 10110
Female 3201 3470 5257 5312 5701 6418 5442
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 3611 3879 3585 40 4496 5083 4662
Female 159 1695 1538 162 1816 2087 1875
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 2295 2328 2399 2658 2988 3379 2957
Female 839 828 936 957 1085 126 1107
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017 q1 q2 q3
All drug 3948 4061 6589 6894 7458 8430 7696 889150252325 1075831326045 167997701832
Heroin 1452 1472 1571 1681 1891 2173 191 302341597796 476222826087 215786123488
Opioid 2447 2636 2429 2636 2956 3382 3088 208009807928 283004552352 271305063812
Q12016-Q12017 Q22016-Q22017 Q32016-Q32017
All drug 889150252325 1075831326045 167997701832
Heroin 302341597796 476222826087 215786123488
Opioid 208009807928 283004552352 271305063812
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Heroin 136 674 701 1251 1486 -1209
Opioid 77 -785 853 1212 1442 -868
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Heroin 1452 1472 1571 1681 1891 2173 191
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Heroin 1452 1472 1571 1681 1891 2173 191
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Opioid 77 -785 853 1212 1442 -868
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Heroin 136 674 701 1251 1486 -1209
Q12016-Q12017 Q12016-Q12017 Q12016-Q12017
Q22016-Q22017 Q22016-Q22017 Q22016-Q22017
Q32016-Q32017 Q32016-Q32017 Q32016-Q32017
Column1 Any opioid Natural and semi-synthetic opioid analgesic Methadone Synthetic opioid analgesic excluding methadone Heroin
1999 1 03 03 07
21 1 04 03 07
2001 24 12 05 03 06
32 15 08 04 07
2003 35 17 1 05 07
39 18 13 06 06
2005 43 19 15 06 07
51 23 18 09 07
2007 54 27 18 07 08
57 3 16 08 1
2009 59 31 15 1 11
62 35 15 1 1
2011 66 37 14 08 14
67 35 12 08 19
2013 74 35 11 1 27
86 38 11 18 34
2015 104 39 1 31 41
133 44 1 62 49
1999 1999 1999 1999
1 04 03 07
2001 2001 2001 2001
15 08 04 07
2003 2003 2003 2003
18 13 06 06
2005 2005 2005 2005
23 18 09 07
2007 2007 2007 2007
3 16 08 1
2009 2009 2009 2009
35 15 1 1
2011 2011 2011 2011
35 12 08 19
2013 2013 2013 2013
38 11 18 34
2015 2015 2015 2015
44 1 62 49
Page 10: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

2000 Rapid Increase in Drug Overdose Death Rates by County

SOURCE NCHS Data Visualization Gallery

Rx Summit wwwNationalRxDrugAbuseSummitorgSOURCE NCHS Data Visualization Gallery

2005 Rapid Increase in Drug Overdose Death Rates by County

Rx Summit wwwNationalRxDrugAbuseSummitorgSOURCE NCHS Data Visualization Gallery

2010 Rapid Increase in Drug Overdose Death Rates by County

Rx Summit wwwNationalRxDrugAbuseSummitorgSOURCE NCHS Data Visualization Gallery

2016 Rapid Increase in Drug Overdose Death Rates by County

Rx Summit wwwNationalRxDrugAbuseSummitorg

RISE IN OPIOID DEATHS

Overlapping Entangled but Distinct Epidemics

Natural and semi-synthetic opioidslike oxycodone or hydrocodone

Methadone

Heroin

SOURCE National Vital Statistics System Mortality File

Dea

ths

per 1

000

00 p

opul

atio

n

Chart1

Synthetic opioidslike fentanyl
3 Waves
Almost 351630 people have died from an opioid overdose during 1999-2016
Natural and semi-synthetic opioid analgesic
Methadone
Synthetic opioid analgesic excluding methadone
Heroin
1
03
03
07
12
05
03
06
17
1
05
07
19
15
06
07
27
18
07
08
31
15
1
11
37
14
08
14
35
11
1
27
39
1
31
41

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

CDCrsquos Pillars on Opioids Conducting surveillance and research

Building state local and tribal prevention efforts

Supporting healthcare providers and health systems

Partnering with public safety officials

Encouraging consumers to make safe choices about opioids raising awareness about prescription opioid misuse and overdose

Rx Summit wwwNationalRxDrugAbuseSummitorg

Enhanced State Opioid Overdose Surveillance (ESOOS) 12 states funded in September 2016 20 additional states and the

District of Columbia funded in September 2017 (through September 2019)

Strategy One Increase timeliness of non-fatal opioid overdose reporting- Use syndromic surveillance to establish an early warning system to

detect sharp increases or decreases in non-fatal opioid overdoses - Three indicators suspected all-drug opioid and heroin

Alaska California Connecticut Delaware DC Florida Georgia Illinois Indiana Kentucky Louisiana Maine Maryland Massachusetts Michigan Minnesota Missouri Nevada New Hampshire New Jersey New Mexico North Carolina Ohio Oklahoma Pennsylvania Rhode Island Tennessee Utah Vermont Virginia Washington West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

Enhanced State Opioid Overdose Surveillance (ESOOS) Strategy Two Increase timeliness of fatal opioid overdose

reporting- Capture detailed information on toxicology death scene

investigations and other risk factors that may be associated with a fatal overdose

Strategy Three widespread dissemination- Rapidly disseminate surveillance findings to key stakeholders

working to prevent or respond to opioid overdoses

ESOOS program expansion in September 2017- At least 60 for comprehensive toxicology testing for opioid-

involved deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

Funded ESOOS states

Rx Summit wwwNationalRxDrugAbuseSummitorg

Enhanced State Opioid Overdose Surveillance (ESOOS)

Nonfatal Opioid Overdoses Reported

Quarterly

Emergency Department Visits EMS Transports

Fatal Opioid Overdoses Reported within 8 months

of death

Death CertificatesMEC reports

Toxicology reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

Next Two Presentationshellip

The Utilization of Emergency Department Syndromic Surveillance and Emergency Medical Services Data to Monitor Nonfatal Opioid Overdoses ndash Dr Alana Vivolo-Kantor

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System ndash Dr Julie OrsquoDonnell

Rx Summit wwwNationalRxDrugAbuseSummitorg

The utilization of emergency department syndromic surveillance

and emergency medical services data to monitor nonfatal opioid

overdosesPresenter Alana Vivolo-Kantor PhD

Behavioral ScientistCenters for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Julie OrsquoDonnell R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Alana Vivolo-Kantor PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Why Emergency Department and Emergency Medical Service Data for Surveillance

Need- Identify areas experiencing rapid increases in opioid overdoses to

inform responses- More quickly identify promising practices to reduce opioid overdoses

Proven utility to public health and scalable- Local jurisdictions already using it to track and respond to drug

overdoses- Findings from Epi-Aid investigations and collaborative work with states- Leverage existing state and national resources (BioSenseESSENCE)

Action at local and national level- Track quarterly trends across the nation to inform national policy- Improve more rapid local and state public health response

Rx Summit wwwNationalRxDrugAbuseSummitorg

Our Philosophy

Focus on detecting change- Pushing system by looking at trend data over quarters- Some jurisdictions may be able to get and report preliminary

burden estimates

Jurisdiction-driven definitions will outperform national definitions- Local flexibility enhances quality and utility by accounting for large

variance in text entries and coding

National guidance- National definition will provide a good starting place- Guidance to encourage common conceptual definition (eg no

withdrawaldetox) and learn from previous work

Rx Summit wwwNationalRxDrugAbuseSummitorg

Our approach

Non-fatal overdoses

Emergency Department

Near real-time ED collection (ie

syndromic ESSENCE)

Case-level or aggregate data shared

through ESSENCE (BioSense) or directly

with CDC

DischargeBilling Data

Case-level or aggregate data shared

directly with CDC

Emergency Medical Services

Case-level or aggregate data shared

directly with CDC

Includes breakdown by

sex age group and county of residence

Raceethnicity is optional

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency Department Data

Two sources- Near real-time syndromic data (visit information within 24-48 hours)- Lagged hospital billing or claims data (usually within 3-4 weeks)

Different variables used- Discharge diagnosis codes (eg ICD-10-CM) ndash available in billing

data and sometimes in syndromic- Free text fields (eg chief complaint provided by Doctor) ndash

available only in syndromic

Rx Summit wwwNationalRxDrugAbuseSummitorg

Case definitions for suspected overdose

If syndromic- Uses both discharge codes (ie ICD-9-CM ICD-10-CM and

SNOMED) and free text fields such as chief complaint or triage notes

- Free text searches use common terms slang and misspellings (eg herion instead of heroin)

If hospital billing or claimshellip- Uses only discharge codes (ie ICD-9-CM ICD-10-CM and

SNOMED)

Discharge codes use are for acute unintentional or undetermined drug poisoning (eg T401X1A in ICD-10-CM) and may also include some substance useabuse codes (ie F11 in ICD-10-CM)

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency medical services data

Capture potential EMS transports to EDs- Excludes instances where individual is pronounced deceased on

the scene inter-facility transports and when EMTs provide no ldquotreatmentrdquo (eg patient refused or required no treatment or transport)

Different variables used- Chief Complaint Secondary complaint- Narrative- Provider Impression- ICD-1O-CM codes- Medication administered (ie Naloxone)- Response to medication administered (ie awake following

Naloxone administration)

Rx Summit wwwNationalRxDrugAbuseSummitorg

Challenges in EMS data

Transition to newer versions of NEMSIS- Some states working in up to three versions (v221 v334 amp

v340)

Different case definitions in different versions

Missing data feeds

Not all EMS agencies share data

Varying time frame in when data is received- lt24 hours to 6 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Data submission process

Rx Summit wwwNationalRxDrugAbuseSummitorg

Sample quality control report

ObsSTATE YEAR QUARTER ERROR_TEXTTOTAL ED VISITS (GENDER)

TOTAL ED VISITS (AGE)

1XX 2017 1 ED Visits mismatch 98287 98309

2XX 2017 2 ED Visits mismatch 98195 98230

3XX 2017 3 ED Visits mismatch 99167 99205

Rx Summit wwwNationalRxDrugAbuseSummitorg

Sample site report

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results All drug (11 sites)

0

10

20

30

40

50

60

70

80

90

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d al

l dru

g ov

erdo

se ra

tes

by

100

00 E

D v

isits

Quarter year

-2000

-1000

000

1000

2000

3000

4000

5000

6000

7000

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Opioid (11 sites)

0

5

10

15

20

25

30

35

40

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Heroin (11 sites)

0

5

10

15

20

25

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-15

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

Annual percentage changes (11 sites)

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Chart1

All drug
Heroin
Opioid
889150252325
302341597796
208009807928
1075831326045
476222826087
283004552352
167997701832
215786123488
271305063812

table with overall

table with overall

All drug
Suspected all drug overdose rates by 10000 ED visits

Sheet1

All drug

table by sex

Opioid
Quarter year
Suspected opioid overdose rates by 10000 ED visits

table by age

Opioid

table by state

Heroin
Quarter year
Suspected opioid overdose rates by 10000 ED visits
Heroin
All drug
Heroin
Opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Summary

Stable increases for all drug and heroin from Q1 2016 to Q3 2017- Opioid had stable increases from Q3 2016 to Q2 2017

Moderate decreases from Q2 to Q3 2017- 9 for all drug 9 for opioid and 12 for heroin

Annual percentage changes were above 15 increases- Q1 to Q1 89 all drug 30 heroin amp 21 opioid- Q2 to Q2 108 all drug 48 heroin amp 28 opioid- Q3 to Q3 17 all drug 22 heroin amp 27 opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency department data dissemination efforts

ldquoOpioid Overdoses Treated in Emergency Departmentsrdquo -httpswwwcdcgovvitalsignsopioid-overdosesindexhtml

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose

Reporting System

Presenter Julie OrsquoDonnell PhD MPHEpidemiologist

Centers for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Alana Vivolo-Kantor R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Julie OrsquoDonnell PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Increase in deaths outpaces increase in use

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid

overdose

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid overdose surveillance

Track specific substances contributing to overdose deaths

Detect newly-emerging substances involved in overdose

Determine risk factors circumstances associated with fatal overdose

Assess common drug combinations Provide more timely data on overdose deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

State Unintentional Drug Overdose Reporting System (SUDORS)

Death certificates

Medical examiner

coroner reportsToxicology

reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data submitted bi-annually

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

1 Data entry started

2 Data entry finished

1 Data entry started

2 Data entry finished

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS leverages National Violent Death Reporting System (NVDRS) platform

- Basic descriptors- Compare across demographics

- Recent release from institution- Overdose location - Survival time

- Mental health diagnoses- Substance abuse treatment history

- Substances present- Substances contributing to death

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Maine 1941 -1273 225 278 1523 -201 3951 -692 257 -813 2945 981 793 656 -299 -2255 3199 2197
Massachusetts na na na na na na 1561 -157 -848 -1148 311 1897 553 -31 -13 -1632 456 2146
New Hampshire 511 1514 -1438 -832 2583 -961 318 64 -433 -1791 2967 -876 825 -184 -1002 -2016 3363 -17
Pennsylvania na na 869 -102 1211 -116 na na 2979 1751 2589 -594 na na 2601 1534 2735 -735
Rhode Island na na 735 -790 1002 -1594 na na 28 454 544 -1191 na na 121 1057 566 -3262
West Virginia -1596 875 2978 -1543 409 -1651 -367 995 4331 -1664 402 -2377 -769 1847 4571 -1584 -199 -3022
Kentucky -102 1242 -1707 2211 1092 -1468 1095 5192 -2694 4045 352 -2002 -043 5541 -3206 5012 -408 -1624
New Mexico 2932 283 521 -078 445 -716 255 -1298 2611 151 -501 -1093 -487 -3061 3227 987 -1715 323
Missouri 068 -304 754 028 114 421 292 827 477 -177 954 767 -046 1839 096 -512 966 125
Ohio na na 107 1216 1596 -1865 na na 2274 2567 2167 -3194 na na 2182 2254 2086 -3348
Wisconsin -229 1388 861 2928 888 931 -948 986 1712 6728 322 314 -1457 91 983 9621 196 668
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 1514 2112 1966 2017 1853 2398 2634
Massachusetts 7036 8133 8006 7327 6486 6687 7956
New Hampshire 3806 3927 4179 3998 3282 4255 3882
Pennsylvania na na 1265 1641 1929 2428 2284
Rhode Island na na 1498 154 161 1698 1496
West Virginia 2258 2176 2392 3428 2857 2972 2266
Kentucky 2095 2325 3532 258 3624 3752 3001
New Mexico 1927 1976 1719 2168 2201 2091 1862
Missouri 1472 1515 1641 1719 1688 185 1991
Ohio na na 236 2897 3641 443 3015
Wisconsin 664 601 66 773 1294 1336 1377
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 502 9 959 931 721 952 1161
Massachusetts 4035 4258 4126 359 3004 3141 3815
New Hampshire 2514 2721 2671 2403 1919 2564 2128
Pennsylvania na na 1013 1277 1473 1876 1738
Rhode Island na na 803 812 898 949 639
West Virginia 1496 1381 1636 2384 2006 1966 1372
Kentucky 1772 1764 2741 1863 2796 2682 2247
New Mexico 902 858 595 787 865 717 74
Missouri 1002 997 118 1192 1131 124 1255
Ohio na na 1804 2198 2693 3254 2165
Wisconsin 286 244 267 293 575 586 625
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 5609 6697 5845 5976 6142 7078 6936
Massachusetts na na na na na na na
New Hampshire 5678 5968 6872 5883 5394 6787 6135
Pennsylvania na na 8374 9102 9010 10100 9983
Rhode Island na na 3567 3829 3527 3880 3262
West Virginia 4628 3889 4229 5489 4642 4832 4034
Kentucky 6756 6687 7517 6234 7613 8444 7205
New Mexico 5291 6842 7036 7402 7345 7672 7123
Missouri 3213 3235 3137 3373 3383 3421 3565
Ohio na na 8696 8789 9859 11432 9300
Wisconsin 2724 2661 3031 3291 4255 4633 5064
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
15 to 24
25 to 34
35 to 54
55 and up
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Male -140 7355 827 901 1286 -927 742 -758 1157 1241 1306 -829 146 301 1082 1242 1306 -1249
Female 841 5151 103 733 1257 -1521 659 -922 533 1204 1494 -1014 -132 1299 229 1331 1617 -1214
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 4888 4820 8365 9057 9873 11142 10110
Female 3201 3470 5257 5312 5701 6418 5442
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 3611 3879 3585 40 4496 5083 4662
Female 159 1695 1538 162 1816 2087 1875
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 2295 2328 2399 2658 2988 3379 2957
Female 839 828 936 957 1085 126 1107
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017 q1 q2 q3
All drug 3948 4061 6589 6894 7458 8430 7696 889150252325 1075831326045 167997701832
Heroin 1452 1472 1571 1681 1891 2173 191 302341597796 476222826087 215786123488
Opioid 2447 2636 2429 2636 2956 3382 3088 208009807928 283004552352 271305063812
Q12016-Q12017 Q22016-Q22017 Q32016-Q32017
All drug 889150252325 1075831326045 167997701832
Heroin 302341597796 476222826087 215786123488
Opioid 208009807928 283004552352 271305063812
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Heroin 136 674 701 1251 1486 -1209
Opioid 77 -785 853 1212 1442 -868
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Heroin 1452 1472 1571 1681 1891 2173 191
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Heroin 1452 1472 1571 1681 1891 2173 191
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Opioid 77 -785 853 1212 1442 -868
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Heroin 136 674 701 1251 1486 -1209
Q12016-Q12017 Q12016-Q12017 Q12016-Q12017
Q22016-Q22017 Q22016-Q22017 Q22016-Q22017
Q32016-Q32017 Q32016-Q32017 Q32016-Q32017
Column1 Any opioid Natural and semi-synthetic opioid analgesic Methadone Synthetic opioid analgesic excluding methadone Heroin
1999 1 03 03 07
21 1 04 03 07
2001 24 12 05 03 06
32 15 08 04 07
2003 35 17 1 05 07
39 18 13 06 06
2005 43 19 15 06 07
51 23 18 09 07
2007 54 27 18 07 08
57 3 16 08 1
2009 59 31 15 1 11
62 35 15 1 1
2011 66 37 14 08 14
67 35 12 08 19
2013 74 35 11 1 27
86 38 11 18 34
2015 104 39 1 31 41
133 44 1 62 49
1999 1999 1999 1999
1 04 03 07
2001 2001 2001 2001
15 08 04 07
2003 2003 2003 2003
18 13 06 06
2005 2005 2005 2005
23 18 09 07
2007 2007 2007 2007
3 16 08 1
2009 2009 2009 2009
35 15 1 1
2011 2011 2011 2011
35 12 08 19
2013 2013 2013 2013
38 11 18 34
2015 2015 2015 2015
44 1 62 49
Page 11: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorgSOURCE NCHS Data Visualization Gallery

2005 Rapid Increase in Drug Overdose Death Rates by County

Rx Summit wwwNationalRxDrugAbuseSummitorgSOURCE NCHS Data Visualization Gallery

2010 Rapid Increase in Drug Overdose Death Rates by County

Rx Summit wwwNationalRxDrugAbuseSummitorgSOURCE NCHS Data Visualization Gallery

2016 Rapid Increase in Drug Overdose Death Rates by County

Rx Summit wwwNationalRxDrugAbuseSummitorg

RISE IN OPIOID DEATHS

Overlapping Entangled but Distinct Epidemics

Natural and semi-synthetic opioidslike oxycodone or hydrocodone

Methadone

Heroin

SOURCE National Vital Statistics System Mortality File

Dea

ths

per 1

000

00 p

opul

atio

n

Chart1

Synthetic opioidslike fentanyl
3 Waves
Almost 351630 people have died from an opioid overdose during 1999-2016
Natural and semi-synthetic opioid analgesic
Methadone
Synthetic opioid analgesic excluding methadone
Heroin
1
03
03
07
12
05
03
06
17
1
05
07
19
15
06
07
27
18
07
08
31
15
1
11
37
14
08
14
35
11
1
27
39
1
31
41

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

CDCrsquos Pillars on Opioids Conducting surveillance and research

Building state local and tribal prevention efforts

Supporting healthcare providers and health systems

Partnering with public safety officials

Encouraging consumers to make safe choices about opioids raising awareness about prescription opioid misuse and overdose

Rx Summit wwwNationalRxDrugAbuseSummitorg

Enhanced State Opioid Overdose Surveillance (ESOOS) 12 states funded in September 2016 20 additional states and the

District of Columbia funded in September 2017 (through September 2019)

Strategy One Increase timeliness of non-fatal opioid overdose reporting- Use syndromic surveillance to establish an early warning system to

detect sharp increases or decreases in non-fatal opioid overdoses - Three indicators suspected all-drug opioid and heroin

Alaska California Connecticut Delaware DC Florida Georgia Illinois Indiana Kentucky Louisiana Maine Maryland Massachusetts Michigan Minnesota Missouri Nevada New Hampshire New Jersey New Mexico North Carolina Ohio Oklahoma Pennsylvania Rhode Island Tennessee Utah Vermont Virginia Washington West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

Enhanced State Opioid Overdose Surveillance (ESOOS) Strategy Two Increase timeliness of fatal opioid overdose

reporting- Capture detailed information on toxicology death scene

investigations and other risk factors that may be associated with a fatal overdose

Strategy Three widespread dissemination- Rapidly disseminate surveillance findings to key stakeholders

working to prevent or respond to opioid overdoses

ESOOS program expansion in September 2017- At least 60 for comprehensive toxicology testing for opioid-

involved deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

Funded ESOOS states

Rx Summit wwwNationalRxDrugAbuseSummitorg

Enhanced State Opioid Overdose Surveillance (ESOOS)

Nonfatal Opioid Overdoses Reported

Quarterly

Emergency Department Visits EMS Transports

Fatal Opioid Overdoses Reported within 8 months

of death

Death CertificatesMEC reports

Toxicology reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

Next Two Presentationshellip

The Utilization of Emergency Department Syndromic Surveillance and Emergency Medical Services Data to Monitor Nonfatal Opioid Overdoses ndash Dr Alana Vivolo-Kantor

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System ndash Dr Julie OrsquoDonnell

Rx Summit wwwNationalRxDrugAbuseSummitorg

The utilization of emergency department syndromic surveillance

and emergency medical services data to monitor nonfatal opioid

overdosesPresenter Alana Vivolo-Kantor PhD

Behavioral ScientistCenters for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Julie OrsquoDonnell R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Alana Vivolo-Kantor PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Why Emergency Department and Emergency Medical Service Data for Surveillance

Need- Identify areas experiencing rapid increases in opioid overdoses to

inform responses- More quickly identify promising practices to reduce opioid overdoses

Proven utility to public health and scalable- Local jurisdictions already using it to track and respond to drug

overdoses- Findings from Epi-Aid investigations and collaborative work with states- Leverage existing state and national resources (BioSenseESSENCE)

Action at local and national level- Track quarterly trends across the nation to inform national policy- Improve more rapid local and state public health response

Rx Summit wwwNationalRxDrugAbuseSummitorg

Our Philosophy

Focus on detecting change- Pushing system by looking at trend data over quarters- Some jurisdictions may be able to get and report preliminary

burden estimates

Jurisdiction-driven definitions will outperform national definitions- Local flexibility enhances quality and utility by accounting for large

variance in text entries and coding

National guidance- National definition will provide a good starting place- Guidance to encourage common conceptual definition (eg no

withdrawaldetox) and learn from previous work

Rx Summit wwwNationalRxDrugAbuseSummitorg

Our approach

Non-fatal overdoses

Emergency Department

Near real-time ED collection (ie

syndromic ESSENCE)

Case-level or aggregate data shared

through ESSENCE (BioSense) or directly

with CDC

DischargeBilling Data

Case-level or aggregate data shared

directly with CDC

Emergency Medical Services

Case-level or aggregate data shared

directly with CDC

Includes breakdown by

sex age group and county of residence

Raceethnicity is optional

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency Department Data

Two sources- Near real-time syndromic data (visit information within 24-48 hours)- Lagged hospital billing or claims data (usually within 3-4 weeks)

Different variables used- Discharge diagnosis codes (eg ICD-10-CM) ndash available in billing

data and sometimes in syndromic- Free text fields (eg chief complaint provided by Doctor) ndash

available only in syndromic

Rx Summit wwwNationalRxDrugAbuseSummitorg

Case definitions for suspected overdose

If syndromic- Uses both discharge codes (ie ICD-9-CM ICD-10-CM and

SNOMED) and free text fields such as chief complaint or triage notes

- Free text searches use common terms slang and misspellings (eg herion instead of heroin)

If hospital billing or claimshellip- Uses only discharge codes (ie ICD-9-CM ICD-10-CM and

SNOMED)

Discharge codes use are for acute unintentional or undetermined drug poisoning (eg T401X1A in ICD-10-CM) and may also include some substance useabuse codes (ie F11 in ICD-10-CM)

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency medical services data

Capture potential EMS transports to EDs- Excludes instances where individual is pronounced deceased on

the scene inter-facility transports and when EMTs provide no ldquotreatmentrdquo (eg patient refused or required no treatment or transport)

Different variables used- Chief Complaint Secondary complaint- Narrative- Provider Impression- ICD-1O-CM codes- Medication administered (ie Naloxone)- Response to medication administered (ie awake following

Naloxone administration)

Rx Summit wwwNationalRxDrugAbuseSummitorg

Challenges in EMS data

Transition to newer versions of NEMSIS- Some states working in up to three versions (v221 v334 amp

v340)

Different case definitions in different versions

Missing data feeds

Not all EMS agencies share data

Varying time frame in when data is received- lt24 hours to 6 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Data submission process

Rx Summit wwwNationalRxDrugAbuseSummitorg

Sample quality control report

ObsSTATE YEAR QUARTER ERROR_TEXTTOTAL ED VISITS (GENDER)

TOTAL ED VISITS (AGE)

1XX 2017 1 ED Visits mismatch 98287 98309

2XX 2017 2 ED Visits mismatch 98195 98230

3XX 2017 3 ED Visits mismatch 99167 99205

Rx Summit wwwNationalRxDrugAbuseSummitorg

Sample site report

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results All drug (11 sites)

0

10

20

30

40

50

60

70

80

90

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d al

l dru

g ov

erdo

se ra

tes

by

100

00 E

D v

isits

Quarter year

-2000

-1000

000

1000

2000

3000

4000

5000

6000

7000

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Opioid (11 sites)

0

5

10

15

20

25

30

35

40

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Heroin (11 sites)

0

5

10

15

20

25

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-15

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

Annual percentage changes (11 sites)

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Chart1

All drug
Heroin
Opioid
889150252325
302341597796
208009807928
1075831326045
476222826087
283004552352
167997701832
215786123488
271305063812

table with overall

table with overall

All drug
Suspected all drug overdose rates by 10000 ED visits

Sheet1

All drug

table by sex

Opioid
Quarter year
Suspected opioid overdose rates by 10000 ED visits

table by age

Opioid

table by state

Heroin
Quarter year
Suspected opioid overdose rates by 10000 ED visits
Heroin
All drug
Heroin
Opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Summary

Stable increases for all drug and heroin from Q1 2016 to Q3 2017- Opioid had stable increases from Q3 2016 to Q2 2017

Moderate decreases from Q2 to Q3 2017- 9 for all drug 9 for opioid and 12 for heroin

Annual percentage changes were above 15 increases- Q1 to Q1 89 all drug 30 heroin amp 21 opioid- Q2 to Q2 108 all drug 48 heroin amp 28 opioid- Q3 to Q3 17 all drug 22 heroin amp 27 opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency department data dissemination efforts

ldquoOpioid Overdoses Treated in Emergency Departmentsrdquo -httpswwwcdcgovvitalsignsopioid-overdosesindexhtml

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose

Reporting System

Presenter Julie OrsquoDonnell PhD MPHEpidemiologist

Centers for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Alana Vivolo-Kantor R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Julie OrsquoDonnell PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Increase in deaths outpaces increase in use

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid

overdose

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid overdose surveillance

Track specific substances contributing to overdose deaths

Detect newly-emerging substances involved in overdose

Determine risk factors circumstances associated with fatal overdose

Assess common drug combinations Provide more timely data on overdose deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

State Unintentional Drug Overdose Reporting System (SUDORS)

Death certificates

Medical examiner

coroner reportsToxicology

reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data submitted bi-annually

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

1 Data entry started

2 Data entry finished

1 Data entry started

2 Data entry finished

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS leverages National Violent Death Reporting System (NVDRS) platform

- Basic descriptors- Compare across demographics

- Recent release from institution- Overdose location - Survival time

- Mental health diagnoses- Substance abuse treatment history

- Substances present- Substances contributing to death

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Maine 1941 -1273 225 278 1523 -201 3951 -692 257 -813 2945 981 793 656 -299 -2255 3199 2197
Massachusetts na na na na na na 1561 -157 -848 -1148 311 1897 553 -31 -13 -1632 456 2146
New Hampshire 511 1514 -1438 -832 2583 -961 318 64 -433 -1791 2967 -876 825 -184 -1002 -2016 3363 -17
Pennsylvania na na 869 -102 1211 -116 na na 2979 1751 2589 -594 na na 2601 1534 2735 -735
Rhode Island na na 735 -790 1002 -1594 na na 28 454 544 -1191 na na 121 1057 566 -3262
West Virginia -1596 875 2978 -1543 409 -1651 -367 995 4331 -1664 402 -2377 -769 1847 4571 -1584 -199 -3022
Kentucky -102 1242 -1707 2211 1092 -1468 1095 5192 -2694 4045 352 -2002 -043 5541 -3206 5012 -408 -1624
New Mexico 2932 283 521 -078 445 -716 255 -1298 2611 151 -501 -1093 -487 -3061 3227 987 -1715 323
Missouri 068 -304 754 028 114 421 292 827 477 -177 954 767 -046 1839 096 -512 966 125
Ohio na na 107 1216 1596 -1865 na na 2274 2567 2167 -3194 na na 2182 2254 2086 -3348
Wisconsin -229 1388 861 2928 888 931 -948 986 1712 6728 322 314 -1457 91 983 9621 196 668
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 1514 2112 1966 2017 1853 2398 2634
Massachusetts 7036 8133 8006 7327 6486 6687 7956
New Hampshire 3806 3927 4179 3998 3282 4255 3882
Pennsylvania na na 1265 1641 1929 2428 2284
Rhode Island na na 1498 154 161 1698 1496
West Virginia 2258 2176 2392 3428 2857 2972 2266
Kentucky 2095 2325 3532 258 3624 3752 3001
New Mexico 1927 1976 1719 2168 2201 2091 1862
Missouri 1472 1515 1641 1719 1688 185 1991
Ohio na na 236 2897 3641 443 3015
Wisconsin 664 601 66 773 1294 1336 1377
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 502 9 959 931 721 952 1161
Massachusetts 4035 4258 4126 359 3004 3141 3815
New Hampshire 2514 2721 2671 2403 1919 2564 2128
Pennsylvania na na 1013 1277 1473 1876 1738
Rhode Island na na 803 812 898 949 639
West Virginia 1496 1381 1636 2384 2006 1966 1372
Kentucky 1772 1764 2741 1863 2796 2682 2247
New Mexico 902 858 595 787 865 717 74
Missouri 1002 997 118 1192 1131 124 1255
Ohio na na 1804 2198 2693 3254 2165
Wisconsin 286 244 267 293 575 586 625
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 5609 6697 5845 5976 6142 7078 6936
Massachusetts na na na na na na na
New Hampshire 5678 5968 6872 5883 5394 6787 6135
Pennsylvania na na 8374 9102 9010 10100 9983
Rhode Island na na 3567 3829 3527 3880 3262
West Virginia 4628 3889 4229 5489 4642 4832 4034
Kentucky 6756 6687 7517 6234 7613 8444 7205
New Mexico 5291 6842 7036 7402 7345 7672 7123
Missouri 3213 3235 3137 3373 3383 3421 3565
Ohio na na 8696 8789 9859 11432 9300
Wisconsin 2724 2661 3031 3291 4255 4633 5064
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
15 to 24
25 to 34
35 to 54
55 and up
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Male -140 7355 827 901 1286 -927 742 -758 1157 1241 1306 -829 146 301 1082 1242 1306 -1249
Female 841 5151 103 733 1257 -1521 659 -922 533 1204 1494 -1014 -132 1299 229 1331 1617 -1214
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 4888 4820 8365 9057 9873 11142 10110
Female 3201 3470 5257 5312 5701 6418 5442
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 3611 3879 3585 40 4496 5083 4662
Female 159 1695 1538 162 1816 2087 1875
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 2295 2328 2399 2658 2988 3379 2957
Female 839 828 936 957 1085 126 1107
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017 q1 q2 q3
All drug 3948 4061 6589 6894 7458 8430 7696 889150252325 1075831326045 167997701832
Heroin 1452 1472 1571 1681 1891 2173 191 302341597796 476222826087 215786123488
Opioid 2447 2636 2429 2636 2956 3382 3088 208009807928 283004552352 271305063812
Q12016-Q12017 Q22016-Q22017 Q32016-Q32017
All drug 889150252325 1075831326045 167997701832
Heroin 302341597796 476222826087 215786123488
Opioid 208009807928 283004552352 271305063812
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Heroin 136 674 701 1251 1486 -1209
Opioid 77 -785 853 1212 1442 -868
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Heroin 1452 1472 1571 1681 1891 2173 191
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Heroin 1452 1472 1571 1681 1891 2173 191
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Opioid 77 -785 853 1212 1442 -868
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Heroin 136 674 701 1251 1486 -1209
Q12016-Q12017 Q12016-Q12017 Q12016-Q12017
Q22016-Q22017 Q22016-Q22017 Q22016-Q22017
Q32016-Q32017 Q32016-Q32017 Q32016-Q32017
Column1 Any opioid Natural and semi-synthetic opioid analgesic Methadone Synthetic opioid analgesic excluding methadone Heroin
1999 1 03 03 07
21 1 04 03 07
2001 24 12 05 03 06
32 15 08 04 07
2003 35 17 1 05 07
39 18 13 06 06
2005 43 19 15 06 07
51 23 18 09 07
2007 54 27 18 07 08
57 3 16 08 1
2009 59 31 15 1 11
62 35 15 1 1
2011 66 37 14 08 14
67 35 12 08 19
2013 74 35 11 1 27
86 38 11 18 34
2015 104 39 1 31 41
133 44 1 62 49
1999 1999 1999 1999
1 04 03 07
2001 2001 2001 2001
15 08 04 07
2003 2003 2003 2003
18 13 06 06
2005 2005 2005 2005
23 18 09 07
2007 2007 2007 2007
3 16 08 1
2009 2009 2009 2009
35 15 1 1
2011 2011 2011 2011
35 12 08 19
2013 2013 2013 2013
38 11 18 34
2015 2015 2015 2015
44 1 62 49
Page 12: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorgSOURCE NCHS Data Visualization Gallery

2010 Rapid Increase in Drug Overdose Death Rates by County

Rx Summit wwwNationalRxDrugAbuseSummitorgSOURCE NCHS Data Visualization Gallery

2016 Rapid Increase in Drug Overdose Death Rates by County

Rx Summit wwwNationalRxDrugAbuseSummitorg

RISE IN OPIOID DEATHS

Overlapping Entangled but Distinct Epidemics

Natural and semi-synthetic opioidslike oxycodone or hydrocodone

Methadone

Heroin

SOURCE National Vital Statistics System Mortality File

Dea

ths

per 1

000

00 p

opul

atio

n

Chart1

Synthetic opioidslike fentanyl
3 Waves
Almost 351630 people have died from an opioid overdose during 1999-2016
Natural and semi-synthetic opioid analgesic
Methadone
Synthetic opioid analgesic excluding methadone
Heroin
1
03
03
07
12
05
03
06
17
1
05
07
19
15
06
07
27
18
07
08
31
15
1
11
37
14
08
14
35
11
1
27
39
1
31
41

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

CDCrsquos Pillars on Opioids Conducting surveillance and research

Building state local and tribal prevention efforts

Supporting healthcare providers and health systems

Partnering with public safety officials

Encouraging consumers to make safe choices about opioids raising awareness about prescription opioid misuse and overdose

Rx Summit wwwNationalRxDrugAbuseSummitorg

Enhanced State Opioid Overdose Surveillance (ESOOS) 12 states funded in September 2016 20 additional states and the

District of Columbia funded in September 2017 (through September 2019)

Strategy One Increase timeliness of non-fatal opioid overdose reporting- Use syndromic surveillance to establish an early warning system to

detect sharp increases or decreases in non-fatal opioid overdoses - Three indicators suspected all-drug opioid and heroin

Alaska California Connecticut Delaware DC Florida Georgia Illinois Indiana Kentucky Louisiana Maine Maryland Massachusetts Michigan Minnesota Missouri Nevada New Hampshire New Jersey New Mexico North Carolina Ohio Oklahoma Pennsylvania Rhode Island Tennessee Utah Vermont Virginia Washington West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

Enhanced State Opioid Overdose Surveillance (ESOOS) Strategy Two Increase timeliness of fatal opioid overdose

reporting- Capture detailed information on toxicology death scene

investigations and other risk factors that may be associated with a fatal overdose

Strategy Three widespread dissemination- Rapidly disseminate surveillance findings to key stakeholders

working to prevent or respond to opioid overdoses

ESOOS program expansion in September 2017- At least 60 for comprehensive toxicology testing for opioid-

involved deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

Funded ESOOS states

Rx Summit wwwNationalRxDrugAbuseSummitorg

Enhanced State Opioid Overdose Surveillance (ESOOS)

Nonfatal Opioid Overdoses Reported

Quarterly

Emergency Department Visits EMS Transports

Fatal Opioid Overdoses Reported within 8 months

of death

Death CertificatesMEC reports

Toxicology reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

Next Two Presentationshellip

The Utilization of Emergency Department Syndromic Surveillance and Emergency Medical Services Data to Monitor Nonfatal Opioid Overdoses ndash Dr Alana Vivolo-Kantor

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System ndash Dr Julie OrsquoDonnell

Rx Summit wwwNationalRxDrugAbuseSummitorg

The utilization of emergency department syndromic surveillance

and emergency medical services data to monitor nonfatal opioid

overdosesPresenter Alana Vivolo-Kantor PhD

Behavioral ScientistCenters for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Julie OrsquoDonnell R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Alana Vivolo-Kantor PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Why Emergency Department and Emergency Medical Service Data for Surveillance

Need- Identify areas experiencing rapid increases in opioid overdoses to

inform responses- More quickly identify promising practices to reduce opioid overdoses

Proven utility to public health and scalable- Local jurisdictions already using it to track and respond to drug

overdoses- Findings from Epi-Aid investigations and collaborative work with states- Leverage existing state and national resources (BioSenseESSENCE)

Action at local and national level- Track quarterly trends across the nation to inform national policy- Improve more rapid local and state public health response

Rx Summit wwwNationalRxDrugAbuseSummitorg

Our Philosophy

Focus on detecting change- Pushing system by looking at trend data over quarters- Some jurisdictions may be able to get and report preliminary

burden estimates

Jurisdiction-driven definitions will outperform national definitions- Local flexibility enhances quality and utility by accounting for large

variance in text entries and coding

National guidance- National definition will provide a good starting place- Guidance to encourage common conceptual definition (eg no

withdrawaldetox) and learn from previous work

Rx Summit wwwNationalRxDrugAbuseSummitorg

Our approach

Non-fatal overdoses

Emergency Department

Near real-time ED collection (ie

syndromic ESSENCE)

Case-level or aggregate data shared

through ESSENCE (BioSense) or directly

with CDC

DischargeBilling Data

Case-level or aggregate data shared

directly with CDC

Emergency Medical Services

Case-level or aggregate data shared

directly with CDC

Includes breakdown by

sex age group and county of residence

Raceethnicity is optional

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency Department Data

Two sources- Near real-time syndromic data (visit information within 24-48 hours)- Lagged hospital billing or claims data (usually within 3-4 weeks)

Different variables used- Discharge diagnosis codes (eg ICD-10-CM) ndash available in billing

data and sometimes in syndromic- Free text fields (eg chief complaint provided by Doctor) ndash

available only in syndromic

Rx Summit wwwNationalRxDrugAbuseSummitorg

Case definitions for suspected overdose

If syndromic- Uses both discharge codes (ie ICD-9-CM ICD-10-CM and

SNOMED) and free text fields such as chief complaint or triage notes

- Free text searches use common terms slang and misspellings (eg herion instead of heroin)

If hospital billing or claimshellip- Uses only discharge codes (ie ICD-9-CM ICD-10-CM and

SNOMED)

Discharge codes use are for acute unintentional or undetermined drug poisoning (eg T401X1A in ICD-10-CM) and may also include some substance useabuse codes (ie F11 in ICD-10-CM)

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency medical services data

Capture potential EMS transports to EDs- Excludes instances where individual is pronounced deceased on

the scene inter-facility transports and when EMTs provide no ldquotreatmentrdquo (eg patient refused or required no treatment or transport)

Different variables used- Chief Complaint Secondary complaint- Narrative- Provider Impression- ICD-1O-CM codes- Medication administered (ie Naloxone)- Response to medication administered (ie awake following

Naloxone administration)

Rx Summit wwwNationalRxDrugAbuseSummitorg

Challenges in EMS data

Transition to newer versions of NEMSIS- Some states working in up to three versions (v221 v334 amp

v340)

Different case definitions in different versions

Missing data feeds

Not all EMS agencies share data

Varying time frame in when data is received- lt24 hours to 6 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Data submission process

Rx Summit wwwNationalRxDrugAbuseSummitorg

Sample quality control report

ObsSTATE YEAR QUARTER ERROR_TEXTTOTAL ED VISITS (GENDER)

TOTAL ED VISITS (AGE)

1XX 2017 1 ED Visits mismatch 98287 98309

2XX 2017 2 ED Visits mismatch 98195 98230

3XX 2017 3 ED Visits mismatch 99167 99205

Rx Summit wwwNationalRxDrugAbuseSummitorg

Sample site report

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results All drug (11 sites)

0

10

20

30

40

50

60

70

80

90

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d al

l dru

g ov

erdo

se ra

tes

by

100

00 E

D v

isits

Quarter year

-2000

-1000

000

1000

2000

3000

4000

5000

6000

7000

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Opioid (11 sites)

0

5

10

15

20

25

30

35

40

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Heroin (11 sites)

0

5

10

15

20

25

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-15

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

Annual percentage changes (11 sites)

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Chart1

All drug
Heroin
Opioid
889150252325
302341597796
208009807928
1075831326045
476222826087
283004552352
167997701832
215786123488
271305063812

table with overall

table with overall

All drug
Suspected all drug overdose rates by 10000 ED visits

Sheet1

All drug

table by sex

Opioid
Quarter year
Suspected opioid overdose rates by 10000 ED visits

table by age

Opioid

table by state

Heroin
Quarter year
Suspected opioid overdose rates by 10000 ED visits
Heroin
All drug
Heroin
Opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Summary

Stable increases for all drug and heroin from Q1 2016 to Q3 2017- Opioid had stable increases from Q3 2016 to Q2 2017

Moderate decreases from Q2 to Q3 2017- 9 for all drug 9 for opioid and 12 for heroin

Annual percentage changes were above 15 increases- Q1 to Q1 89 all drug 30 heroin amp 21 opioid- Q2 to Q2 108 all drug 48 heroin amp 28 opioid- Q3 to Q3 17 all drug 22 heroin amp 27 opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency department data dissemination efforts

ldquoOpioid Overdoses Treated in Emergency Departmentsrdquo -httpswwwcdcgovvitalsignsopioid-overdosesindexhtml

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose

Reporting System

Presenter Julie OrsquoDonnell PhD MPHEpidemiologist

Centers for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Alana Vivolo-Kantor R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Julie OrsquoDonnell PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Increase in deaths outpaces increase in use

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid

overdose

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid overdose surveillance

Track specific substances contributing to overdose deaths

Detect newly-emerging substances involved in overdose

Determine risk factors circumstances associated with fatal overdose

Assess common drug combinations Provide more timely data on overdose deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

State Unintentional Drug Overdose Reporting System (SUDORS)

Death certificates

Medical examiner

coroner reportsToxicology

reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data submitted bi-annually

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

1 Data entry started

2 Data entry finished

1 Data entry started

2 Data entry finished

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS leverages National Violent Death Reporting System (NVDRS) platform

- Basic descriptors- Compare across demographics

- Recent release from institution- Overdose location - Survival time

- Mental health diagnoses- Substance abuse treatment history

- Substances present- Substances contributing to death

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Maine 1941 -1273 225 278 1523 -201 3951 -692 257 -813 2945 981 793 656 -299 -2255 3199 2197
Massachusetts na na na na na na 1561 -157 -848 -1148 311 1897 553 -31 -13 -1632 456 2146
New Hampshire 511 1514 -1438 -832 2583 -961 318 64 -433 -1791 2967 -876 825 -184 -1002 -2016 3363 -17
Pennsylvania na na 869 -102 1211 -116 na na 2979 1751 2589 -594 na na 2601 1534 2735 -735
Rhode Island na na 735 -790 1002 -1594 na na 28 454 544 -1191 na na 121 1057 566 -3262
West Virginia -1596 875 2978 -1543 409 -1651 -367 995 4331 -1664 402 -2377 -769 1847 4571 -1584 -199 -3022
Kentucky -102 1242 -1707 2211 1092 -1468 1095 5192 -2694 4045 352 -2002 -043 5541 -3206 5012 -408 -1624
New Mexico 2932 283 521 -078 445 -716 255 -1298 2611 151 -501 -1093 -487 -3061 3227 987 -1715 323
Missouri 068 -304 754 028 114 421 292 827 477 -177 954 767 -046 1839 096 -512 966 125
Ohio na na 107 1216 1596 -1865 na na 2274 2567 2167 -3194 na na 2182 2254 2086 -3348
Wisconsin -229 1388 861 2928 888 931 -948 986 1712 6728 322 314 -1457 91 983 9621 196 668
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 1514 2112 1966 2017 1853 2398 2634
Massachusetts 7036 8133 8006 7327 6486 6687 7956
New Hampshire 3806 3927 4179 3998 3282 4255 3882
Pennsylvania na na 1265 1641 1929 2428 2284
Rhode Island na na 1498 154 161 1698 1496
West Virginia 2258 2176 2392 3428 2857 2972 2266
Kentucky 2095 2325 3532 258 3624 3752 3001
New Mexico 1927 1976 1719 2168 2201 2091 1862
Missouri 1472 1515 1641 1719 1688 185 1991
Ohio na na 236 2897 3641 443 3015
Wisconsin 664 601 66 773 1294 1336 1377
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 502 9 959 931 721 952 1161
Massachusetts 4035 4258 4126 359 3004 3141 3815
New Hampshire 2514 2721 2671 2403 1919 2564 2128
Pennsylvania na na 1013 1277 1473 1876 1738
Rhode Island na na 803 812 898 949 639
West Virginia 1496 1381 1636 2384 2006 1966 1372
Kentucky 1772 1764 2741 1863 2796 2682 2247
New Mexico 902 858 595 787 865 717 74
Missouri 1002 997 118 1192 1131 124 1255
Ohio na na 1804 2198 2693 3254 2165
Wisconsin 286 244 267 293 575 586 625
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 5609 6697 5845 5976 6142 7078 6936
Massachusetts na na na na na na na
New Hampshire 5678 5968 6872 5883 5394 6787 6135
Pennsylvania na na 8374 9102 9010 10100 9983
Rhode Island na na 3567 3829 3527 3880 3262
West Virginia 4628 3889 4229 5489 4642 4832 4034
Kentucky 6756 6687 7517 6234 7613 8444 7205
New Mexico 5291 6842 7036 7402 7345 7672 7123
Missouri 3213 3235 3137 3373 3383 3421 3565
Ohio na na 8696 8789 9859 11432 9300
Wisconsin 2724 2661 3031 3291 4255 4633 5064
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
15 to 24
25 to 34
35 to 54
55 and up
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Male -140 7355 827 901 1286 -927 742 -758 1157 1241 1306 -829 146 301 1082 1242 1306 -1249
Female 841 5151 103 733 1257 -1521 659 -922 533 1204 1494 -1014 -132 1299 229 1331 1617 -1214
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 4888 4820 8365 9057 9873 11142 10110
Female 3201 3470 5257 5312 5701 6418 5442
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 3611 3879 3585 40 4496 5083 4662
Female 159 1695 1538 162 1816 2087 1875
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 2295 2328 2399 2658 2988 3379 2957
Female 839 828 936 957 1085 126 1107
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017 q1 q2 q3
All drug 3948 4061 6589 6894 7458 8430 7696 889150252325 1075831326045 167997701832
Heroin 1452 1472 1571 1681 1891 2173 191 302341597796 476222826087 215786123488
Opioid 2447 2636 2429 2636 2956 3382 3088 208009807928 283004552352 271305063812
Q12016-Q12017 Q22016-Q22017 Q32016-Q32017
All drug 889150252325 1075831326045 167997701832
Heroin 302341597796 476222826087 215786123488
Opioid 208009807928 283004552352 271305063812
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Heroin 136 674 701 1251 1486 -1209
Opioid 77 -785 853 1212 1442 -868
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Heroin 1452 1472 1571 1681 1891 2173 191
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Heroin 1452 1472 1571 1681 1891 2173 191
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Opioid 77 -785 853 1212 1442 -868
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Heroin 136 674 701 1251 1486 -1209
Q12016-Q12017 Q12016-Q12017 Q12016-Q12017
Q22016-Q22017 Q22016-Q22017 Q22016-Q22017
Q32016-Q32017 Q32016-Q32017 Q32016-Q32017
Column1 Any opioid Natural and semi-synthetic opioid analgesic Methadone Synthetic opioid analgesic excluding methadone Heroin
1999 1 03 03 07
21 1 04 03 07
2001 24 12 05 03 06
32 15 08 04 07
2003 35 17 1 05 07
39 18 13 06 06
2005 43 19 15 06 07
51 23 18 09 07
2007 54 27 18 07 08
57 3 16 08 1
2009 59 31 15 1 11
62 35 15 1 1
2011 66 37 14 08 14
67 35 12 08 19
2013 74 35 11 1 27
86 38 11 18 34
2015 104 39 1 31 41
133 44 1 62 49
1999 1999 1999 1999
1 04 03 07
2001 2001 2001 2001
15 08 04 07
2003 2003 2003 2003
18 13 06 06
2005 2005 2005 2005
23 18 09 07
2007 2007 2007 2007
3 16 08 1
2009 2009 2009 2009
35 15 1 1
2011 2011 2011 2011
35 12 08 19
2013 2013 2013 2013
38 11 18 34
2015 2015 2015 2015
44 1 62 49
Page 13: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorgSOURCE NCHS Data Visualization Gallery

2016 Rapid Increase in Drug Overdose Death Rates by County

Rx Summit wwwNationalRxDrugAbuseSummitorg

RISE IN OPIOID DEATHS

Overlapping Entangled but Distinct Epidemics

Natural and semi-synthetic opioidslike oxycodone or hydrocodone

Methadone

Heroin

SOURCE National Vital Statistics System Mortality File

Dea

ths

per 1

000

00 p

opul

atio

n

Chart1

Synthetic opioidslike fentanyl
3 Waves
Almost 351630 people have died from an opioid overdose during 1999-2016
Natural and semi-synthetic opioid analgesic
Methadone
Synthetic opioid analgesic excluding methadone
Heroin
1
03
03
07
12
05
03
06
17
1
05
07
19
15
06
07
27
18
07
08
31
15
1
11
37
14
08
14
35
11
1
27
39
1
31
41

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

CDCrsquos Pillars on Opioids Conducting surveillance and research

Building state local and tribal prevention efforts

Supporting healthcare providers and health systems

Partnering with public safety officials

Encouraging consumers to make safe choices about opioids raising awareness about prescription opioid misuse and overdose

Rx Summit wwwNationalRxDrugAbuseSummitorg

Enhanced State Opioid Overdose Surveillance (ESOOS) 12 states funded in September 2016 20 additional states and the

District of Columbia funded in September 2017 (through September 2019)

Strategy One Increase timeliness of non-fatal opioid overdose reporting- Use syndromic surveillance to establish an early warning system to

detect sharp increases or decreases in non-fatal opioid overdoses - Three indicators suspected all-drug opioid and heroin

Alaska California Connecticut Delaware DC Florida Georgia Illinois Indiana Kentucky Louisiana Maine Maryland Massachusetts Michigan Minnesota Missouri Nevada New Hampshire New Jersey New Mexico North Carolina Ohio Oklahoma Pennsylvania Rhode Island Tennessee Utah Vermont Virginia Washington West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

Enhanced State Opioid Overdose Surveillance (ESOOS) Strategy Two Increase timeliness of fatal opioid overdose

reporting- Capture detailed information on toxicology death scene

investigations and other risk factors that may be associated with a fatal overdose

Strategy Three widespread dissemination- Rapidly disseminate surveillance findings to key stakeholders

working to prevent or respond to opioid overdoses

ESOOS program expansion in September 2017- At least 60 for comprehensive toxicology testing for opioid-

involved deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

Funded ESOOS states

Rx Summit wwwNationalRxDrugAbuseSummitorg

Enhanced State Opioid Overdose Surveillance (ESOOS)

Nonfatal Opioid Overdoses Reported

Quarterly

Emergency Department Visits EMS Transports

Fatal Opioid Overdoses Reported within 8 months

of death

Death CertificatesMEC reports

Toxicology reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

Next Two Presentationshellip

The Utilization of Emergency Department Syndromic Surveillance and Emergency Medical Services Data to Monitor Nonfatal Opioid Overdoses ndash Dr Alana Vivolo-Kantor

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System ndash Dr Julie OrsquoDonnell

Rx Summit wwwNationalRxDrugAbuseSummitorg

The utilization of emergency department syndromic surveillance

and emergency medical services data to monitor nonfatal opioid

overdosesPresenter Alana Vivolo-Kantor PhD

Behavioral ScientistCenters for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Julie OrsquoDonnell R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Alana Vivolo-Kantor PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Why Emergency Department and Emergency Medical Service Data for Surveillance

Need- Identify areas experiencing rapid increases in opioid overdoses to

inform responses- More quickly identify promising practices to reduce opioid overdoses

Proven utility to public health and scalable- Local jurisdictions already using it to track and respond to drug

overdoses- Findings from Epi-Aid investigations and collaborative work with states- Leverage existing state and national resources (BioSenseESSENCE)

Action at local and national level- Track quarterly trends across the nation to inform national policy- Improve more rapid local and state public health response

Rx Summit wwwNationalRxDrugAbuseSummitorg

Our Philosophy

Focus on detecting change- Pushing system by looking at trend data over quarters- Some jurisdictions may be able to get and report preliminary

burden estimates

Jurisdiction-driven definitions will outperform national definitions- Local flexibility enhances quality and utility by accounting for large

variance in text entries and coding

National guidance- National definition will provide a good starting place- Guidance to encourage common conceptual definition (eg no

withdrawaldetox) and learn from previous work

Rx Summit wwwNationalRxDrugAbuseSummitorg

Our approach

Non-fatal overdoses

Emergency Department

Near real-time ED collection (ie

syndromic ESSENCE)

Case-level or aggregate data shared

through ESSENCE (BioSense) or directly

with CDC

DischargeBilling Data

Case-level or aggregate data shared

directly with CDC

Emergency Medical Services

Case-level or aggregate data shared

directly with CDC

Includes breakdown by

sex age group and county of residence

Raceethnicity is optional

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency Department Data

Two sources- Near real-time syndromic data (visit information within 24-48 hours)- Lagged hospital billing or claims data (usually within 3-4 weeks)

Different variables used- Discharge diagnosis codes (eg ICD-10-CM) ndash available in billing

data and sometimes in syndromic- Free text fields (eg chief complaint provided by Doctor) ndash

available only in syndromic

Rx Summit wwwNationalRxDrugAbuseSummitorg

Case definitions for suspected overdose

If syndromic- Uses both discharge codes (ie ICD-9-CM ICD-10-CM and

SNOMED) and free text fields such as chief complaint or triage notes

- Free text searches use common terms slang and misspellings (eg herion instead of heroin)

If hospital billing or claimshellip- Uses only discharge codes (ie ICD-9-CM ICD-10-CM and

SNOMED)

Discharge codes use are for acute unintentional or undetermined drug poisoning (eg T401X1A in ICD-10-CM) and may also include some substance useabuse codes (ie F11 in ICD-10-CM)

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency medical services data

Capture potential EMS transports to EDs- Excludes instances where individual is pronounced deceased on

the scene inter-facility transports and when EMTs provide no ldquotreatmentrdquo (eg patient refused or required no treatment or transport)

Different variables used- Chief Complaint Secondary complaint- Narrative- Provider Impression- ICD-1O-CM codes- Medication administered (ie Naloxone)- Response to medication administered (ie awake following

Naloxone administration)

Rx Summit wwwNationalRxDrugAbuseSummitorg

Challenges in EMS data

Transition to newer versions of NEMSIS- Some states working in up to three versions (v221 v334 amp

v340)

Different case definitions in different versions

Missing data feeds

Not all EMS agencies share data

Varying time frame in when data is received- lt24 hours to 6 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Data submission process

Rx Summit wwwNationalRxDrugAbuseSummitorg

Sample quality control report

ObsSTATE YEAR QUARTER ERROR_TEXTTOTAL ED VISITS (GENDER)

TOTAL ED VISITS (AGE)

1XX 2017 1 ED Visits mismatch 98287 98309

2XX 2017 2 ED Visits mismatch 98195 98230

3XX 2017 3 ED Visits mismatch 99167 99205

Rx Summit wwwNationalRxDrugAbuseSummitorg

Sample site report

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results All drug (11 sites)

0

10

20

30

40

50

60

70

80

90

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d al

l dru

g ov

erdo

se ra

tes

by

100

00 E

D v

isits

Quarter year

-2000

-1000

000

1000

2000

3000

4000

5000

6000

7000

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Opioid (11 sites)

0

5

10

15

20

25

30

35

40

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Heroin (11 sites)

0

5

10

15

20

25

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-15

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

Annual percentage changes (11 sites)

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Chart1

All drug
Heroin
Opioid
889150252325
302341597796
208009807928
1075831326045
476222826087
283004552352
167997701832
215786123488
271305063812

table with overall

table with overall

All drug
Suspected all drug overdose rates by 10000 ED visits

Sheet1

All drug

table by sex

Opioid
Quarter year
Suspected opioid overdose rates by 10000 ED visits

table by age

Opioid

table by state

Heroin
Quarter year
Suspected opioid overdose rates by 10000 ED visits
Heroin
All drug
Heroin
Opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Summary

Stable increases for all drug and heroin from Q1 2016 to Q3 2017- Opioid had stable increases from Q3 2016 to Q2 2017

Moderate decreases from Q2 to Q3 2017- 9 for all drug 9 for opioid and 12 for heroin

Annual percentage changes were above 15 increases- Q1 to Q1 89 all drug 30 heroin amp 21 opioid- Q2 to Q2 108 all drug 48 heroin amp 28 opioid- Q3 to Q3 17 all drug 22 heroin amp 27 opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency department data dissemination efforts

ldquoOpioid Overdoses Treated in Emergency Departmentsrdquo -httpswwwcdcgovvitalsignsopioid-overdosesindexhtml

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose

Reporting System

Presenter Julie OrsquoDonnell PhD MPHEpidemiologist

Centers for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Alana Vivolo-Kantor R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Julie OrsquoDonnell PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Increase in deaths outpaces increase in use

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid

overdose

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid overdose surveillance

Track specific substances contributing to overdose deaths

Detect newly-emerging substances involved in overdose

Determine risk factors circumstances associated with fatal overdose

Assess common drug combinations Provide more timely data on overdose deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

State Unintentional Drug Overdose Reporting System (SUDORS)

Death certificates

Medical examiner

coroner reportsToxicology

reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data submitted bi-annually

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

1 Data entry started

2 Data entry finished

1 Data entry started

2 Data entry finished

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS leverages National Violent Death Reporting System (NVDRS) platform

- Basic descriptors- Compare across demographics

- Recent release from institution- Overdose location - Survival time

- Mental health diagnoses- Substance abuse treatment history

- Substances present- Substances contributing to death

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Maine 1941 -1273 225 278 1523 -201 3951 -692 257 -813 2945 981 793 656 -299 -2255 3199 2197
Massachusetts na na na na na na 1561 -157 -848 -1148 311 1897 553 -31 -13 -1632 456 2146
New Hampshire 511 1514 -1438 -832 2583 -961 318 64 -433 -1791 2967 -876 825 -184 -1002 -2016 3363 -17
Pennsylvania na na 869 -102 1211 -116 na na 2979 1751 2589 -594 na na 2601 1534 2735 -735
Rhode Island na na 735 -790 1002 -1594 na na 28 454 544 -1191 na na 121 1057 566 -3262
West Virginia -1596 875 2978 -1543 409 -1651 -367 995 4331 -1664 402 -2377 -769 1847 4571 -1584 -199 -3022
Kentucky -102 1242 -1707 2211 1092 -1468 1095 5192 -2694 4045 352 -2002 -043 5541 -3206 5012 -408 -1624
New Mexico 2932 283 521 -078 445 -716 255 -1298 2611 151 -501 -1093 -487 -3061 3227 987 -1715 323
Missouri 068 -304 754 028 114 421 292 827 477 -177 954 767 -046 1839 096 -512 966 125
Ohio na na 107 1216 1596 -1865 na na 2274 2567 2167 -3194 na na 2182 2254 2086 -3348
Wisconsin -229 1388 861 2928 888 931 -948 986 1712 6728 322 314 -1457 91 983 9621 196 668
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 1514 2112 1966 2017 1853 2398 2634
Massachusetts 7036 8133 8006 7327 6486 6687 7956
New Hampshire 3806 3927 4179 3998 3282 4255 3882
Pennsylvania na na 1265 1641 1929 2428 2284
Rhode Island na na 1498 154 161 1698 1496
West Virginia 2258 2176 2392 3428 2857 2972 2266
Kentucky 2095 2325 3532 258 3624 3752 3001
New Mexico 1927 1976 1719 2168 2201 2091 1862
Missouri 1472 1515 1641 1719 1688 185 1991
Ohio na na 236 2897 3641 443 3015
Wisconsin 664 601 66 773 1294 1336 1377
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 502 9 959 931 721 952 1161
Massachusetts 4035 4258 4126 359 3004 3141 3815
New Hampshire 2514 2721 2671 2403 1919 2564 2128
Pennsylvania na na 1013 1277 1473 1876 1738
Rhode Island na na 803 812 898 949 639
West Virginia 1496 1381 1636 2384 2006 1966 1372
Kentucky 1772 1764 2741 1863 2796 2682 2247
New Mexico 902 858 595 787 865 717 74
Missouri 1002 997 118 1192 1131 124 1255
Ohio na na 1804 2198 2693 3254 2165
Wisconsin 286 244 267 293 575 586 625
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 5609 6697 5845 5976 6142 7078 6936
Massachusetts na na na na na na na
New Hampshire 5678 5968 6872 5883 5394 6787 6135
Pennsylvania na na 8374 9102 9010 10100 9983
Rhode Island na na 3567 3829 3527 3880 3262
West Virginia 4628 3889 4229 5489 4642 4832 4034
Kentucky 6756 6687 7517 6234 7613 8444 7205
New Mexico 5291 6842 7036 7402 7345 7672 7123
Missouri 3213 3235 3137 3373 3383 3421 3565
Ohio na na 8696 8789 9859 11432 9300
Wisconsin 2724 2661 3031 3291 4255 4633 5064
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
15 to 24
25 to 34
35 to 54
55 and up
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Male -140 7355 827 901 1286 -927 742 -758 1157 1241 1306 -829 146 301 1082 1242 1306 -1249
Female 841 5151 103 733 1257 -1521 659 -922 533 1204 1494 -1014 -132 1299 229 1331 1617 -1214
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 4888 4820 8365 9057 9873 11142 10110
Female 3201 3470 5257 5312 5701 6418 5442
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 3611 3879 3585 40 4496 5083 4662
Female 159 1695 1538 162 1816 2087 1875
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 2295 2328 2399 2658 2988 3379 2957
Female 839 828 936 957 1085 126 1107
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017 q1 q2 q3
All drug 3948 4061 6589 6894 7458 8430 7696 889150252325 1075831326045 167997701832
Heroin 1452 1472 1571 1681 1891 2173 191 302341597796 476222826087 215786123488
Opioid 2447 2636 2429 2636 2956 3382 3088 208009807928 283004552352 271305063812
Q12016-Q12017 Q22016-Q22017 Q32016-Q32017
All drug 889150252325 1075831326045 167997701832
Heroin 302341597796 476222826087 215786123488
Opioid 208009807928 283004552352 271305063812
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Heroin 136 674 701 1251 1486 -1209
Opioid 77 -785 853 1212 1442 -868
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Heroin 1452 1472 1571 1681 1891 2173 191
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Heroin 1452 1472 1571 1681 1891 2173 191
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Opioid 77 -785 853 1212 1442 -868
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Heroin 136 674 701 1251 1486 -1209
Q12016-Q12017 Q12016-Q12017 Q12016-Q12017
Q22016-Q22017 Q22016-Q22017 Q22016-Q22017
Q32016-Q32017 Q32016-Q32017 Q32016-Q32017
Column1 Any opioid Natural and semi-synthetic opioid analgesic Methadone Synthetic opioid analgesic excluding methadone Heroin
1999 1 03 03 07
21 1 04 03 07
2001 24 12 05 03 06
32 15 08 04 07
2003 35 17 1 05 07
39 18 13 06 06
2005 43 19 15 06 07
51 23 18 09 07
2007 54 27 18 07 08
57 3 16 08 1
2009 59 31 15 1 11
62 35 15 1 1
2011 66 37 14 08 14
67 35 12 08 19
2013 74 35 11 1 27
86 38 11 18 34
2015 104 39 1 31 41
133 44 1 62 49
1999 1999 1999 1999
1 04 03 07
2001 2001 2001 2001
15 08 04 07
2003 2003 2003 2003
18 13 06 06
2005 2005 2005 2005
23 18 09 07
2007 2007 2007 2007
3 16 08 1
2009 2009 2009 2009
35 15 1 1
2011 2011 2011 2011
35 12 08 19
2013 2013 2013 2013
38 11 18 34
2015 2015 2015 2015
44 1 62 49
Page 14: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

RISE IN OPIOID DEATHS

Overlapping Entangled but Distinct Epidemics

Natural and semi-synthetic opioidslike oxycodone or hydrocodone

Methadone

Heroin

SOURCE National Vital Statistics System Mortality File

Dea

ths

per 1

000

00 p

opul

atio

n

Chart1

Synthetic opioidslike fentanyl
3 Waves
Almost 351630 people have died from an opioid overdose during 1999-2016
Natural and semi-synthetic opioid analgesic
Methadone
Synthetic opioid analgesic excluding methadone
Heroin
1
03
03
07
12
05
03
06
17
1
05
07
19
15
06
07
27
18
07
08
31
15
1
11
37
14
08
14
35
11
1
27
39
1
31
41

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

CDCrsquos Pillars on Opioids Conducting surveillance and research

Building state local and tribal prevention efforts

Supporting healthcare providers and health systems

Partnering with public safety officials

Encouraging consumers to make safe choices about opioids raising awareness about prescription opioid misuse and overdose

Rx Summit wwwNationalRxDrugAbuseSummitorg

Enhanced State Opioid Overdose Surveillance (ESOOS) 12 states funded in September 2016 20 additional states and the

District of Columbia funded in September 2017 (through September 2019)

Strategy One Increase timeliness of non-fatal opioid overdose reporting- Use syndromic surveillance to establish an early warning system to

detect sharp increases or decreases in non-fatal opioid overdoses - Three indicators suspected all-drug opioid and heroin

Alaska California Connecticut Delaware DC Florida Georgia Illinois Indiana Kentucky Louisiana Maine Maryland Massachusetts Michigan Minnesota Missouri Nevada New Hampshire New Jersey New Mexico North Carolina Ohio Oklahoma Pennsylvania Rhode Island Tennessee Utah Vermont Virginia Washington West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

Enhanced State Opioid Overdose Surveillance (ESOOS) Strategy Two Increase timeliness of fatal opioid overdose

reporting- Capture detailed information on toxicology death scene

investigations and other risk factors that may be associated with a fatal overdose

Strategy Three widespread dissemination- Rapidly disseminate surveillance findings to key stakeholders

working to prevent or respond to opioid overdoses

ESOOS program expansion in September 2017- At least 60 for comprehensive toxicology testing for opioid-

involved deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

Funded ESOOS states

Rx Summit wwwNationalRxDrugAbuseSummitorg

Enhanced State Opioid Overdose Surveillance (ESOOS)

Nonfatal Opioid Overdoses Reported

Quarterly

Emergency Department Visits EMS Transports

Fatal Opioid Overdoses Reported within 8 months

of death

Death CertificatesMEC reports

Toxicology reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

Next Two Presentationshellip

The Utilization of Emergency Department Syndromic Surveillance and Emergency Medical Services Data to Monitor Nonfatal Opioid Overdoses ndash Dr Alana Vivolo-Kantor

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System ndash Dr Julie OrsquoDonnell

Rx Summit wwwNationalRxDrugAbuseSummitorg

The utilization of emergency department syndromic surveillance

and emergency medical services data to monitor nonfatal opioid

overdosesPresenter Alana Vivolo-Kantor PhD

Behavioral ScientistCenters for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Julie OrsquoDonnell R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Alana Vivolo-Kantor PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Why Emergency Department and Emergency Medical Service Data for Surveillance

Need- Identify areas experiencing rapid increases in opioid overdoses to

inform responses- More quickly identify promising practices to reduce opioid overdoses

Proven utility to public health and scalable- Local jurisdictions already using it to track and respond to drug

overdoses- Findings from Epi-Aid investigations and collaborative work with states- Leverage existing state and national resources (BioSenseESSENCE)

Action at local and national level- Track quarterly trends across the nation to inform national policy- Improve more rapid local and state public health response

Rx Summit wwwNationalRxDrugAbuseSummitorg

Our Philosophy

Focus on detecting change- Pushing system by looking at trend data over quarters- Some jurisdictions may be able to get and report preliminary

burden estimates

Jurisdiction-driven definitions will outperform national definitions- Local flexibility enhances quality and utility by accounting for large

variance in text entries and coding

National guidance- National definition will provide a good starting place- Guidance to encourage common conceptual definition (eg no

withdrawaldetox) and learn from previous work

Rx Summit wwwNationalRxDrugAbuseSummitorg

Our approach

Non-fatal overdoses

Emergency Department

Near real-time ED collection (ie

syndromic ESSENCE)

Case-level or aggregate data shared

through ESSENCE (BioSense) or directly

with CDC

DischargeBilling Data

Case-level or aggregate data shared

directly with CDC

Emergency Medical Services

Case-level or aggregate data shared

directly with CDC

Includes breakdown by

sex age group and county of residence

Raceethnicity is optional

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency Department Data

Two sources- Near real-time syndromic data (visit information within 24-48 hours)- Lagged hospital billing or claims data (usually within 3-4 weeks)

Different variables used- Discharge diagnosis codes (eg ICD-10-CM) ndash available in billing

data and sometimes in syndromic- Free text fields (eg chief complaint provided by Doctor) ndash

available only in syndromic

Rx Summit wwwNationalRxDrugAbuseSummitorg

Case definitions for suspected overdose

If syndromic- Uses both discharge codes (ie ICD-9-CM ICD-10-CM and

SNOMED) and free text fields such as chief complaint or triage notes

- Free text searches use common terms slang and misspellings (eg herion instead of heroin)

If hospital billing or claimshellip- Uses only discharge codes (ie ICD-9-CM ICD-10-CM and

SNOMED)

Discharge codes use are for acute unintentional or undetermined drug poisoning (eg T401X1A in ICD-10-CM) and may also include some substance useabuse codes (ie F11 in ICD-10-CM)

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency medical services data

Capture potential EMS transports to EDs- Excludes instances where individual is pronounced deceased on

the scene inter-facility transports and when EMTs provide no ldquotreatmentrdquo (eg patient refused or required no treatment or transport)

Different variables used- Chief Complaint Secondary complaint- Narrative- Provider Impression- ICD-1O-CM codes- Medication administered (ie Naloxone)- Response to medication administered (ie awake following

Naloxone administration)

Rx Summit wwwNationalRxDrugAbuseSummitorg

Challenges in EMS data

Transition to newer versions of NEMSIS- Some states working in up to three versions (v221 v334 amp

v340)

Different case definitions in different versions

Missing data feeds

Not all EMS agencies share data

Varying time frame in when data is received- lt24 hours to 6 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Data submission process

Rx Summit wwwNationalRxDrugAbuseSummitorg

Sample quality control report

ObsSTATE YEAR QUARTER ERROR_TEXTTOTAL ED VISITS (GENDER)

TOTAL ED VISITS (AGE)

1XX 2017 1 ED Visits mismatch 98287 98309

2XX 2017 2 ED Visits mismatch 98195 98230

3XX 2017 3 ED Visits mismatch 99167 99205

Rx Summit wwwNationalRxDrugAbuseSummitorg

Sample site report

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results All drug (11 sites)

0

10

20

30

40

50

60

70

80

90

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d al

l dru

g ov

erdo

se ra

tes

by

100

00 E

D v

isits

Quarter year

-2000

-1000

000

1000

2000

3000

4000

5000

6000

7000

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Opioid (11 sites)

0

5

10

15

20

25

30

35

40

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Heroin (11 sites)

0

5

10

15

20

25

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-15

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

Annual percentage changes (11 sites)

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Chart1

All drug
Heroin
Opioid
889150252325
302341597796
208009807928
1075831326045
476222826087
283004552352
167997701832
215786123488
271305063812

table with overall

table with overall

All drug
Suspected all drug overdose rates by 10000 ED visits

Sheet1

All drug

table by sex

Opioid
Quarter year
Suspected opioid overdose rates by 10000 ED visits

table by age

Opioid

table by state

Heroin
Quarter year
Suspected opioid overdose rates by 10000 ED visits
Heroin
All drug
Heroin
Opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Summary

Stable increases for all drug and heroin from Q1 2016 to Q3 2017- Opioid had stable increases from Q3 2016 to Q2 2017

Moderate decreases from Q2 to Q3 2017- 9 for all drug 9 for opioid and 12 for heroin

Annual percentage changes were above 15 increases- Q1 to Q1 89 all drug 30 heroin amp 21 opioid- Q2 to Q2 108 all drug 48 heroin amp 28 opioid- Q3 to Q3 17 all drug 22 heroin amp 27 opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency department data dissemination efforts

ldquoOpioid Overdoses Treated in Emergency Departmentsrdquo -httpswwwcdcgovvitalsignsopioid-overdosesindexhtml

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose

Reporting System

Presenter Julie OrsquoDonnell PhD MPHEpidemiologist

Centers for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Alana Vivolo-Kantor R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Julie OrsquoDonnell PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Increase in deaths outpaces increase in use

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid

overdose

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid overdose surveillance

Track specific substances contributing to overdose deaths

Detect newly-emerging substances involved in overdose

Determine risk factors circumstances associated with fatal overdose

Assess common drug combinations Provide more timely data on overdose deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

State Unintentional Drug Overdose Reporting System (SUDORS)

Death certificates

Medical examiner

coroner reportsToxicology

reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data submitted bi-annually

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

1 Data entry started

2 Data entry finished

1 Data entry started

2 Data entry finished

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS leverages National Violent Death Reporting System (NVDRS) platform

- Basic descriptors- Compare across demographics

- Recent release from institution- Overdose location - Survival time

- Mental health diagnoses- Substance abuse treatment history

- Substances present- Substances contributing to death

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Maine 1941 -1273 225 278 1523 -201 3951 -692 257 -813 2945 981 793 656 -299 -2255 3199 2197
Massachusetts na na na na na na 1561 -157 -848 -1148 311 1897 553 -31 -13 -1632 456 2146
New Hampshire 511 1514 -1438 -832 2583 -961 318 64 -433 -1791 2967 -876 825 -184 -1002 -2016 3363 -17
Pennsylvania na na 869 -102 1211 -116 na na 2979 1751 2589 -594 na na 2601 1534 2735 -735
Rhode Island na na 735 -790 1002 -1594 na na 28 454 544 -1191 na na 121 1057 566 -3262
West Virginia -1596 875 2978 -1543 409 -1651 -367 995 4331 -1664 402 -2377 -769 1847 4571 -1584 -199 -3022
Kentucky -102 1242 -1707 2211 1092 -1468 1095 5192 -2694 4045 352 -2002 -043 5541 -3206 5012 -408 -1624
New Mexico 2932 283 521 -078 445 -716 255 -1298 2611 151 -501 -1093 -487 -3061 3227 987 -1715 323
Missouri 068 -304 754 028 114 421 292 827 477 -177 954 767 -046 1839 096 -512 966 125
Ohio na na 107 1216 1596 -1865 na na 2274 2567 2167 -3194 na na 2182 2254 2086 -3348
Wisconsin -229 1388 861 2928 888 931 -948 986 1712 6728 322 314 -1457 91 983 9621 196 668
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 1514 2112 1966 2017 1853 2398 2634
Massachusetts 7036 8133 8006 7327 6486 6687 7956
New Hampshire 3806 3927 4179 3998 3282 4255 3882
Pennsylvania na na 1265 1641 1929 2428 2284
Rhode Island na na 1498 154 161 1698 1496
West Virginia 2258 2176 2392 3428 2857 2972 2266
Kentucky 2095 2325 3532 258 3624 3752 3001
New Mexico 1927 1976 1719 2168 2201 2091 1862
Missouri 1472 1515 1641 1719 1688 185 1991
Ohio na na 236 2897 3641 443 3015
Wisconsin 664 601 66 773 1294 1336 1377
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 502 9 959 931 721 952 1161
Massachusetts 4035 4258 4126 359 3004 3141 3815
New Hampshire 2514 2721 2671 2403 1919 2564 2128
Pennsylvania na na 1013 1277 1473 1876 1738
Rhode Island na na 803 812 898 949 639
West Virginia 1496 1381 1636 2384 2006 1966 1372
Kentucky 1772 1764 2741 1863 2796 2682 2247
New Mexico 902 858 595 787 865 717 74
Missouri 1002 997 118 1192 1131 124 1255
Ohio na na 1804 2198 2693 3254 2165
Wisconsin 286 244 267 293 575 586 625
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 5609 6697 5845 5976 6142 7078 6936
Massachusetts na na na na na na na
New Hampshire 5678 5968 6872 5883 5394 6787 6135
Pennsylvania na na 8374 9102 9010 10100 9983
Rhode Island na na 3567 3829 3527 3880 3262
West Virginia 4628 3889 4229 5489 4642 4832 4034
Kentucky 6756 6687 7517 6234 7613 8444 7205
New Mexico 5291 6842 7036 7402 7345 7672 7123
Missouri 3213 3235 3137 3373 3383 3421 3565
Ohio na na 8696 8789 9859 11432 9300
Wisconsin 2724 2661 3031 3291 4255 4633 5064
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
15 to 24
25 to 34
35 to 54
55 and up
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Male -140 7355 827 901 1286 -927 742 -758 1157 1241 1306 -829 146 301 1082 1242 1306 -1249
Female 841 5151 103 733 1257 -1521 659 -922 533 1204 1494 -1014 -132 1299 229 1331 1617 -1214
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 4888 4820 8365 9057 9873 11142 10110
Female 3201 3470 5257 5312 5701 6418 5442
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 3611 3879 3585 40 4496 5083 4662
Female 159 1695 1538 162 1816 2087 1875
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 2295 2328 2399 2658 2988 3379 2957
Female 839 828 936 957 1085 126 1107
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017 q1 q2 q3
All drug 3948 4061 6589 6894 7458 8430 7696 889150252325 1075831326045 167997701832
Heroin 1452 1472 1571 1681 1891 2173 191 302341597796 476222826087 215786123488
Opioid 2447 2636 2429 2636 2956 3382 3088 208009807928 283004552352 271305063812
Q12016-Q12017 Q22016-Q22017 Q32016-Q32017
All drug 889150252325 1075831326045 167997701832
Heroin 302341597796 476222826087 215786123488
Opioid 208009807928 283004552352 271305063812
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Heroin 136 674 701 1251 1486 -1209
Opioid 77 -785 853 1212 1442 -868
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Heroin 1452 1472 1571 1681 1891 2173 191
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Heroin 1452 1472 1571 1681 1891 2173 191
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Opioid 77 -785 853 1212 1442 -868
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Heroin 136 674 701 1251 1486 -1209
Q12016-Q12017 Q12016-Q12017 Q12016-Q12017
Q22016-Q22017 Q22016-Q22017 Q22016-Q22017
Q32016-Q32017 Q32016-Q32017 Q32016-Q32017
Column1 Any opioid Natural and semi-synthetic opioid analgesic Methadone Synthetic opioid analgesic excluding methadone Heroin
1999 1 03 03 07
21 1 04 03 07
2001 24 12 05 03 06
32 15 08 04 07
2003 35 17 1 05 07
39 18 13 06 06
2005 43 19 15 06 07
51 23 18 09 07
2007 54 27 18 07 08
57 3 16 08 1
2009 59 31 15 1 11
62 35 15 1 1
2011 66 37 14 08 14
67 35 12 08 19
2013 74 35 11 1 27
86 38 11 18 34
2015 104 39 1 31 41
133 44 1 62 49
1999 1999 1999 1999
1 04 03 07
2001 2001 2001 2001
15 08 04 07
2003 2003 2003 2003
18 13 06 06
2005 2005 2005 2005
23 18 09 07
2007 2007 2007 2007
3 16 08 1
2009 2009 2009 2009
35 15 1 1
2011 2011 2011 2011
35 12 08 19
2013 2013 2013 2013
38 11 18 34
2015 2015 2015 2015
44 1 62 49
Page 15: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Chart1

Synthetic opioidslike fentanyl
3 Waves
Almost 351630 people have died from an opioid overdose during 1999-2016
Natural and semi-synthetic opioid analgesic
Methadone
Synthetic opioid analgesic excluding methadone
Heroin
1
03
03
07
12
05
03
06
17
1
05
07
19
15
06
07
27
18
07
08
31
15
1
11
37
14
08
14
35
11
1
27
39
1
31
41

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

CDCrsquos Pillars on Opioids Conducting surveillance and research

Building state local and tribal prevention efforts

Supporting healthcare providers and health systems

Partnering with public safety officials

Encouraging consumers to make safe choices about opioids raising awareness about prescription opioid misuse and overdose

Rx Summit wwwNationalRxDrugAbuseSummitorg

Enhanced State Opioid Overdose Surveillance (ESOOS) 12 states funded in September 2016 20 additional states and the

District of Columbia funded in September 2017 (through September 2019)

Strategy One Increase timeliness of non-fatal opioid overdose reporting- Use syndromic surveillance to establish an early warning system to

detect sharp increases or decreases in non-fatal opioid overdoses - Three indicators suspected all-drug opioid and heroin

Alaska California Connecticut Delaware DC Florida Georgia Illinois Indiana Kentucky Louisiana Maine Maryland Massachusetts Michigan Minnesota Missouri Nevada New Hampshire New Jersey New Mexico North Carolina Ohio Oklahoma Pennsylvania Rhode Island Tennessee Utah Vermont Virginia Washington West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

Enhanced State Opioid Overdose Surveillance (ESOOS) Strategy Two Increase timeliness of fatal opioid overdose

reporting- Capture detailed information on toxicology death scene

investigations and other risk factors that may be associated with a fatal overdose

Strategy Three widespread dissemination- Rapidly disseminate surveillance findings to key stakeholders

working to prevent or respond to opioid overdoses

ESOOS program expansion in September 2017- At least 60 for comprehensive toxicology testing for opioid-

involved deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

Funded ESOOS states

Rx Summit wwwNationalRxDrugAbuseSummitorg

Enhanced State Opioid Overdose Surveillance (ESOOS)

Nonfatal Opioid Overdoses Reported

Quarterly

Emergency Department Visits EMS Transports

Fatal Opioid Overdoses Reported within 8 months

of death

Death CertificatesMEC reports

Toxicology reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

Next Two Presentationshellip

The Utilization of Emergency Department Syndromic Surveillance and Emergency Medical Services Data to Monitor Nonfatal Opioid Overdoses ndash Dr Alana Vivolo-Kantor

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System ndash Dr Julie OrsquoDonnell

Rx Summit wwwNationalRxDrugAbuseSummitorg

The utilization of emergency department syndromic surveillance

and emergency medical services data to monitor nonfatal opioid

overdosesPresenter Alana Vivolo-Kantor PhD

Behavioral ScientistCenters for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Julie OrsquoDonnell R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Alana Vivolo-Kantor PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Why Emergency Department and Emergency Medical Service Data for Surveillance

Need- Identify areas experiencing rapid increases in opioid overdoses to

inform responses- More quickly identify promising practices to reduce opioid overdoses

Proven utility to public health and scalable- Local jurisdictions already using it to track and respond to drug

overdoses- Findings from Epi-Aid investigations and collaborative work with states- Leverage existing state and national resources (BioSenseESSENCE)

Action at local and national level- Track quarterly trends across the nation to inform national policy- Improve more rapid local and state public health response

Rx Summit wwwNationalRxDrugAbuseSummitorg

Our Philosophy

Focus on detecting change- Pushing system by looking at trend data over quarters- Some jurisdictions may be able to get and report preliminary

burden estimates

Jurisdiction-driven definitions will outperform national definitions- Local flexibility enhances quality and utility by accounting for large

variance in text entries and coding

National guidance- National definition will provide a good starting place- Guidance to encourage common conceptual definition (eg no

withdrawaldetox) and learn from previous work

Rx Summit wwwNationalRxDrugAbuseSummitorg

Our approach

Non-fatal overdoses

Emergency Department

Near real-time ED collection (ie

syndromic ESSENCE)

Case-level or aggregate data shared

through ESSENCE (BioSense) or directly

with CDC

DischargeBilling Data

Case-level or aggregate data shared

directly with CDC

Emergency Medical Services

Case-level or aggregate data shared

directly with CDC

Includes breakdown by

sex age group and county of residence

Raceethnicity is optional

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency Department Data

Two sources- Near real-time syndromic data (visit information within 24-48 hours)- Lagged hospital billing or claims data (usually within 3-4 weeks)

Different variables used- Discharge diagnosis codes (eg ICD-10-CM) ndash available in billing

data and sometimes in syndromic- Free text fields (eg chief complaint provided by Doctor) ndash

available only in syndromic

Rx Summit wwwNationalRxDrugAbuseSummitorg

Case definitions for suspected overdose

If syndromic- Uses both discharge codes (ie ICD-9-CM ICD-10-CM and

SNOMED) and free text fields such as chief complaint or triage notes

- Free text searches use common terms slang and misspellings (eg herion instead of heroin)

If hospital billing or claimshellip- Uses only discharge codes (ie ICD-9-CM ICD-10-CM and

SNOMED)

Discharge codes use are for acute unintentional or undetermined drug poisoning (eg T401X1A in ICD-10-CM) and may also include some substance useabuse codes (ie F11 in ICD-10-CM)

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency medical services data

Capture potential EMS transports to EDs- Excludes instances where individual is pronounced deceased on

the scene inter-facility transports and when EMTs provide no ldquotreatmentrdquo (eg patient refused or required no treatment or transport)

Different variables used- Chief Complaint Secondary complaint- Narrative- Provider Impression- ICD-1O-CM codes- Medication administered (ie Naloxone)- Response to medication administered (ie awake following

Naloxone administration)

Rx Summit wwwNationalRxDrugAbuseSummitorg

Challenges in EMS data

Transition to newer versions of NEMSIS- Some states working in up to three versions (v221 v334 amp

v340)

Different case definitions in different versions

Missing data feeds

Not all EMS agencies share data

Varying time frame in when data is received- lt24 hours to 6 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Data submission process

Rx Summit wwwNationalRxDrugAbuseSummitorg

Sample quality control report

ObsSTATE YEAR QUARTER ERROR_TEXTTOTAL ED VISITS (GENDER)

TOTAL ED VISITS (AGE)

1XX 2017 1 ED Visits mismatch 98287 98309

2XX 2017 2 ED Visits mismatch 98195 98230

3XX 2017 3 ED Visits mismatch 99167 99205

Rx Summit wwwNationalRxDrugAbuseSummitorg

Sample site report

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results All drug (11 sites)

0

10

20

30

40

50

60

70

80

90

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d al

l dru

g ov

erdo

se ra

tes

by

100

00 E

D v

isits

Quarter year

-2000

-1000

000

1000

2000

3000

4000

5000

6000

7000

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Opioid (11 sites)

0

5

10

15

20

25

30

35

40

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Heroin (11 sites)

0

5

10

15

20

25

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-15

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

Annual percentage changes (11 sites)

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Chart1

All drug
Heroin
Opioid
889150252325
302341597796
208009807928
1075831326045
476222826087
283004552352
167997701832
215786123488
271305063812

table with overall

table with overall

All drug
Suspected all drug overdose rates by 10000 ED visits

Sheet1

All drug

table by sex

Opioid
Quarter year
Suspected opioid overdose rates by 10000 ED visits

table by age

Opioid

table by state

Heroin
Quarter year
Suspected opioid overdose rates by 10000 ED visits
Heroin
All drug
Heroin
Opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Summary

Stable increases for all drug and heroin from Q1 2016 to Q3 2017- Opioid had stable increases from Q3 2016 to Q2 2017

Moderate decreases from Q2 to Q3 2017- 9 for all drug 9 for opioid and 12 for heroin

Annual percentage changes were above 15 increases- Q1 to Q1 89 all drug 30 heroin amp 21 opioid- Q2 to Q2 108 all drug 48 heroin amp 28 opioid- Q3 to Q3 17 all drug 22 heroin amp 27 opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency department data dissemination efforts

ldquoOpioid Overdoses Treated in Emergency Departmentsrdquo -httpswwwcdcgovvitalsignsopioid-overdosesindexhtml

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose

Reporting System

Presenter Julie OrsquoDonnell PhD MPHEpidemiologist

Centers for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Alana Vivolo-Kantor R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Julie OrsquoDonnell PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Increase in deaths outpaces increase in use

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid

overdose

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid overdose surveillance

Track specific substances contributing to overdose deaths

Detect newly-emerging substances involved in overdose

Determine risk factors circumstances associated with fatal overdose

Assess common drug combinations Provide more timely data on overdose deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

State Unintentional Drug Overdose Reporting System (SUDORS)

Death certificates

Medical examiner

coroner reportsToxicology

reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data submitted bi-annually

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

1 Data entry started

2 Data entry finished

1 Data entry started

2 Data entry finished

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS leverages National Violent Death Reporting System (NVDRS) platform

- Basic descriptors- Compare across demographics

- Recent release from institution- Overdose location - Survival time

- Mental health diagnoses- Substance abuse treatment history

- Substances present- Substances contributing to death

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Maine 1941 -1273 225 278 1523 -201 3951 -692 257 -813 2945 981 793 656 -299 -2255 3199 2197
Massachusetts na na na na na na 1561 -157 -848 -1148 311 1897 553 -31 -13 -1632 456 2146
New Hampshire 511 1514 -1438 -832 2583 -961 318 64 -433 -1791 2967 -876 825 -184 -1002 -2016 3363 -17
Pennsylvania na na 869 -102 1211 -116 na na 2979 1751 2589 -594 na na 2601 1534 2735 -735
Rhode Island na na 735 -790 1002 -1594 na na 28 454 544 -1191 na na 121 1057 566 -3262
West Virginia -1596 875 2978 -1543 409 -1651 -367 995 4331 -1664 402 -2377 -769 1847 4571 -1584 -199 -3022
Kentucky -102 1242 -1707 2211 1092 -1468 1095 5192 -2694 4045 352 -2002 -043 5541 -3206 5012 -408 -1624
New Mexico 2932 283 521 -078 445 -716 255 -1298 2611 151 -501 -1093 -487 -3061 3227 987 -1715 323
Missouri 068 -304 754 028 114 421 292 827 477 -177 954 767 -046 1839 096 -512 966 125
Ohio na na 107 1216 1596 -1865 na na 2274 2567 2167 -3194 na na 2182 2254 2086 -3348
Wisconsin -229 1388 861 2928 888 931 -948 986 1712 6728 322 314 -1457 91 983 9621 196 668
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 1514 2112 1966 2017 1853 2398 2634
Massachusetts 7036 8133 8006 7327 6486 6687 7956
New Hampshire 3806 3927 4179 3998 3282 4255 3882
Pennsylvania na na 1265 1641 1929 2428 2284
Rhode Island na na 1498 154 161 1698 1496
West Virginia 2258 2176 2392 3428 2857 2972 2266
Kentucky 2095 2325 3532 258 3624 3752 3001
New Mexico 1927 1976 1719 2168 2201 2091 1862
Missouri 1472 1515 1641 1719 1688 185 1991
Ohio na na 236 2897 3641 443 3015
Wisconsin 664 601 66 773 1294 1336 1377
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 502 9 959 931 721 952 1161
Massachusetts 4035 4258 4126 359 3004 3141 3815
New Hampshire 2514 2721 2671 2403 1919 2564 2128
Pennsylvania na na 1013 1277 1473 1876 1738
Rhode Island na na 803 812 898 949 639
West Virginia 1496 1381 1636 2384 2006 1966 1372
Kentucky 1772 1764 2741 1863 2796 2682 2247
New Mexico 902 858 595 787 865 717 74
Missouri 1002 997 118 1192 1131 124 1255
Ohio na na 1804 2198 2693 3254 2165
Wisconsin 286 244 267 293 575 586 625
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 5609 6697 5845 5976 6142 7078 6936
Massachusetts na na na na na na na
New Hampshire 5678 5968 6872 5883 5394 6787 6135
Pennsylvania na na 8374 9102 9010 10100 9983
Rhode Island na na 3567 3829 3527 3880 3262
West Virginia 4628 3889 4229 5489 4642 4832 4034
Kentucky 6756 6687 7517 6234 7613 8444 7205
New Mexico 5291 6842 7036 7402 7345 7672 7123
Missouri 3213 3235 3137 3373 3383 3421 3565
Ohio na na 8696 8789 9859 11432 9300
Wisconsin 2724 2661 3031 3291 4255 4633 5064
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
15 to 24
25 to 34
35 to 54
55 and up
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Male -140 7355 827 901 1286 -927 742 -758 1157 1241 1306 -829 146 301 1082 1242 1306 -1249
Female 841 5151 103 733 1257 -1521 659 -922 533 1204 1494 -1014 -132 1299 229 1331 1617 -1214
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 4888 4820 8365 9057 9873 11142 10110
Female 3201 3470 5257 5312 5701 6418 5442
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 3611 3879 3585 40 4496 5083 4662
Female 159 1695 1538 162 1816 2087 1875
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 2295 2328 2399 2658 2988 3379 2957
Female 839 828 936 957 1085 126 1107
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017 q1 q2 q3
All drug 3948 4061 6589 6894 7458 8430 7696 889150252325 1075831326045 167997701832
Heroin 1452 1472 1571 1681 1891 2173 191 302341597796 476222826087 215786123488
Opioid 2447 2636 2429 2636 2956 3382 3088 208009807928 283004552352 271305063812
Q12016-Q12017 Q22016-Q22017 Q32016-Q32017
All drug 889150252325 1075831326045 167997701832
Heroin 302341597796 476222826087 215786123488
Opioid 208009807928 283004552352 271305063812
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Heroin 136 674 701 1251 1486 -1209
Opioid 77 -785 853 1212 1442 -868
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Heroin 1452 1472 1571 1681 1891 2173 191
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Heroin 1452 1472 1571 1681 1891 2173 191
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Opioid 77 -785 853 1212 1442 -868
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Heroin 136 674 701 1251 1486 -1209
Q12016-Q12017 Q12016-Q12017 Q12016-Q12017
Q22016-Q22017 Q22016-Q22017 Q22016-Q22017
Q32016-Q32017 Q32016-Q32017 Q32016-Q32017
Column1 Any opioid Natural and semi-synthetic opioid analgesic Methadone Synthetic opioid analgesic excluding methadone Heroin
1999 1 03 03 07
21 1 04 03 07
2001 24 12 05 03 06
32 15 08 04 07
2003 35 17 1 05 07
39 18 13 06 06
2005 43 19 15 06 07
51 23 18 09 07
2007 54 27 18 07 08
57 3 16 08 1
2009 59 31 15 1 11
62 35 15 1 1
2011 66 37 14 08 14
67 35 12 08 19
2013 74 35 11 1 27
86 38 11 18 34
2015 104 39 1 31 41
133 44 1 62 49
1999 1999 1999 1999
1 04 03 07
2001 2001 2001 2001
15 08 04 07
2003 2003 2003 2003
18 13 06 06
2005 2005 2005 2005
23 18 09 07
2007 2007 2007 2007
3 16 08 1
2009 2009 2009 2009
35 15 1 1
2011 2011 2011 2011
35 12 08 19
2013 2013 2013 2013
38 11 18 34
2015 2015 2015 2015
44 1 62 49
Page 16: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

CDCrsquos Pillars on Opioids Conducting surveillance and research

Building state local and tribal prevention efforts

Supporting healthcare providers and health systems

Partnering with public safety officials

Encouraging consumers to make safe choices about opioids raising awareness about prescription opioid misuse and overdose

Rx Summit wwwNationalRxDrugAbuseSummitorg

Enhanced State Opioid Overdose Surveillance (ESOOS) 12 states funded in September 2016 20 additional states and the

District of Columbia funded in September 2017 (through September 2019)

Strategy One Increase timeliness of non-fatal opioid overdose reporting- Use syndromic surveillance to establish an early warning system to

detect sharp increases or decreases in non-fatal opioid overdoses - Three indicators suspected all-drug opioid and heroin

Alaska California Connecticut Delaware DC Florida Georgia Illinois Indiana Kentucky Louisiana Maine Maryland Massachusetts Michigan Minnesota Missouri Nevada New Hampshire New Jersey New Mexico North Carolina Ohio Oklahoma Pennsylvania Rhode Island Tennessee Utah Vermont Virginia Washington West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

Enhanced State Opioid Overdose Surveillance (ESOOS) Strategy Two Increase timeliness of fatal opioid overdose

reporting- Capture detailed information on toxicology death scene

investigations and other risk factors that may be associated with a fatal overdose

Strategy Three widespread dissemination- Rapidly disseminate surveillance findings to key stakeholders

working to prevent or respond to opioid overdoses

ESOOS program expansion in September 2017- At least 60 for comprehensive toxicology testing for opioid-

involved deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

Funded ESOOS states

Rx Summit wwwNationalRxDrugAbuseSummitorg

Enhanced State Opioid Overdose Surveillance (ESOOS)

Nonfatal Opioid Overdoses Reported

Quarterly

Emergency Department Visits EMS Transports

Fatal Opioid Overdoses Reported within 8 months

of death

Death CertificatesMEC reports

Toxicology reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

Next Two Presentationshellip

The Utilization of Emergency Department Syndromic Surveillance and Emergency Medical Services Data to Monitor Nonfatal Opioid Overdoses ndash Dr Alana Vivolo-Kantor

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System ndash Dr Julie OrsquoDonnell

Rx Summit wwwNationalRxDrugAbuseSummitorg

The utilization of emergency department syndromic surveillance

and emergency medical services data to monitor nonfatal opioid

overdosesPresenter Alana Vivolo-Kantor PhD

Behavioral ScientistCenters for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Julie OrsquoDonnell R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Alana Vivolo-Kantor PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Why Emergency Department and Emergency Medical Service Data for Surveillance

Need- Identify areas experiencing rapid increases in opioid overdoses to

inform responses- More quickly identify promising practices to reduce opioid overdoses

Proven utility to public health and scalable- Local jurisdictions already using it to track and respond to drug

overdoses- Findings from Epi-Aid investigations and collaborative work with states- Leverage existing state and national resources (BioSenseESSENCE)

Action at local and national level- Track quarterly trends across the nation to inform national policy- Improve more rapid local and state public health response

Rx Summit wwwNationalRxDrugAbuseSummitorg

Our Philosophy

Focus on detecting change- Pushing system by looking at trend data over quarters- Some jurisdictions may be able to get and report preliminary

burden estimates

Jurisdiction-driven definitions will outperform national definitions- Local flexibility enhances quality and utility by accounting for large

variance in text entries and coding

National guidance- National definition will provide a good starting place- Guidance to encourage common conceptual definition (eg no

withdrawaldetox) and learn from previous work

Rx Summit wwwNationalRxDrugAbuseSummitorg

Our approach

Non-fatal overdoses

Emergency Department

Near real-time ED collection (ie

syndromic ESSENCE)

Case-level or aggregate data shared

through ESSENCE (BioSense) or directly

with CDC

DischargeBilling Data

Case-level or aggregate data shared

directly with CDC

Emergency Medical Services

Case-level or aggregate data shared

directly with CDC

Includes breakdown by

sex age group and county of residence

Raceethnicity is optional

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency Department Data

Two sources- Near real-time syndromic data (visit information within 24-48 hours)- Lagged hospital billing or claims data (usually within 3-4 weeks)

Different variables used- Discharge diagnosis codes (eg ICD-10-CM) ndash available in billing

data and sometimes in syndromic- Free text fields (eg chief complaint provided by Doctor) ndash

available only in syndromic

Rx Summit wwwNationalRxDrugAbuseSummitorg

Case definitions for suspected overdose

If syndromic- Uses both discharge codes (ie ICD-9-CM ICD-10-CM and

SNOMED) and free text fields such as chief complaint or triage notes

- Free text searches use common terms slang and misspellings (eg herion instead of heroin)

If hospital billing or claimshellip- Uses only discharge codes (ie ICD-9-CM ICD-10-CM and

SNOMED)

Discharge codes use are for acute unintentional or undetermined drug poisoning (eg T401X1A in ICD-10-CM) and may also include some substance useabuse codes (ie F11 in ICD-10-CM)

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency medical services data

Capture potential EMS transports to EDs- Excludes instances where individual is pronounced deceased on

the scene inter-facility transports and when EMTs provide no ldquotreatmentrdquo (eg patient refused or required no treatment or transport)

Different variables used- Chief Complaint Secondary complaint- Narrative- Provider Impression- ICD-1O-CM codes- Medication administered (ie Naloxone)- Response to medication administered (ie awake following

Naloxone administration)

Rx Summit wwwNationalRxDrugAbuseSummitorg

Challenges in EMS data

Transition to newer versions of NEMSIS- Some states working in up to three versions (v221 v334 amp

v340)

Different case definitions in different versions

Missing data feeds

Not all EMS agencies share data

Varying time frame in when data is received- lt24 hours to 6 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Data submission process

Rx Summit wwwNationalRxDrugAbuseSummitorg

Sample quality control report

ObsSTATE YEAR QUARTER ERROR_TEXTTOTAL ED VISITS (GENDER)

TOTAL ED VISITS (AGE)

1XX 2017 1 ED Visits mismatch 98287 98309

2XX 2017 2 ED Visits mismatch 98195 98230

3XX 2017 3 ED Visits mismatch 99167 99205

Rx Summit wwwNationalRxDrugAbuseSummitorg

Sample site report

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results All drug (11 sites)

0

10

20

30

40

50

60

70

80

90

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d al

l dru

g ov

erdo

se ra

tes

by

100

00 E

D v

isits

Quarter year

-2000

-1000

000

1000

2000

3000

4000

5000

6000

7000

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Opioid (11 sites)

0

5

10

15

20

25

30

35

40

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Heroin (11 sites)

0

5

10

15

20

25

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-15

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

Annual percentage changes (11 sites)

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Chart1

All drug
Heroin
Opioid
889150252325
302341597796
208009807928
1075831326045
476222826087
283004552352
167997701832
215786123488
271305063812

table with overall

table with overall

All drug
Suspected all drug overdose rates by 10000 ED visits

Sheet1

All drug

table by sex

Opioid
Quarter year
Suspected opioid overdose rates by 10000 ED visits

table by age

Opioid

table by state

Heroin
Quarter year
Suspected opioid overdose rates by 10000 ED visits
Heroin
All drug
Heroin
Opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Summary

Stable increases for all drug and heroin from Q1 2016 to Q3 2017- Opioid had stable increases from Q3 2016 to Q2 2017

Moderate decreases from Q2 to Q3 2017- 9 for all drug 9 for opioid and 12 for heroin

Annual percentage changes were above 15 increases- Q1 to Q1 89 all drug 30 heroin amp 21 opioid- Q2 to Q2 108 all drug 48 heroin amp 28 opioid- Q3 to Q3 17 all drug 22 heroin amp 27 opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency department data dissemination efforts

ldquoOpioid Overdoses Treated in Emergency Departmentsrdquo -httpswwwcdcgovvitalsignsopioid-overdosesindexhtml

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose

Reporting System

Presenter Julie OrsquoDonnell PhD MPHEpidemiologist

Centers for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Alana Vivolo-Kantor R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Julie OrsquoDonnell PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Increase in deaths outpaces increase in use

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid

overdose

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid overdose surveillance

Track specific substances contributing to overdose deaths

Detect newly-emerging substances involved in overdose

Determine risk factors circumstances associated with fatal overdose

Assess common drug combinations Provide more timely data on overdose deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

State Unintentional Drug Overdose Reporting System (SUDORS)

Death certificates

Medical examiner

coroner reportsToxicology

reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data submitted bi-annually

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

1 Data entry started

2 Data entry finished

1 Data entry started

2 Data entry finished

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS leverages National Violent Death Reporting System (NVDRS) platform

- Basic descriptors- Compare across demographics

- Recent release from institution- Overdose location - Survival time

- Mental health diagnoses- Substance abuse treatment history

- Substances present- Substances contributing to death

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Maine 1941 -1273 225 278 1523 -201 3951 -692 257 -813 2945 981 793 656 -299 -2255 3199 2197
Massachusetts na na na na na na 1561 -157 -848 -1148 311 1897 553 -31 -13 -1632 456 2146
New Hampshire 511 1514 -1438 -832 2583 -961 318 64 -433 -1791 2967 -876 825 -184 -1002 -2016 3363 -17
Pennsylvania na na 869 -102 1211 -116 na na 2979 1751 2589 -594 na na 2601 1534 2735 -735
Rhode Island na na 735 -790 1002 -1594 na na 28 454 544 -1191 na na 121 1057 566 -3262
West Virginia -1596 875 2978 -1543 409 -1651 -367 995 4331 -1664 402 -2377 -769 1847 4571 -1584 -199 -3022
Kentucky -102 1242 -1707 2211 1092 -1468 1095 5192 -2694 4045 352 -2002 -043 5541 -3206 5012 -408 -1624
New Mexico 2932 283 521 -078 445 -716 255 -1298 2611 151 -501 -1093 -487 -3061 3227 987 -1715 323
Missouri 068 -304 754 028 114 421 292 827 477 -177 954 767 -046 1839 096 -512 966 125
Ohio na na 107 1216 1596 -1865 na na 2274 2567 2167 -3194 na na 2182 2254 2086 -3348
Wisconsin -229 1388 861 2928 888 931 -948 986 1712 6728 322 314 -1457 91 983 9621 196 668
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 1514 2112 1966 2017 1853 2398 2634
Massachusetts 7036 8133 8006 7327 6486 6687 7956
New Hampshire 3806 3927 4179 3998 3282 4255 3882
Pennsylvania na na 1265 1641 1929 2428 2284
Rhode Island na na 1498 154 161 1698 1496
West Virginia 2258 2176 2392 3428 2857 2972 2266
Kentucky 2095 2325 3532 258 3624 3752 3001
New Mexico 1927 1976 1719 2168 2201 2091 1862
Missouri 1472 1515 1641 1719 1688 185 1991
Ohio na na 236 2897 3641 443 3015
Wisconsin 664 601 66 773 1294 1336 1377
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 502 9 959 931 721 952 1161
Massachusetts 4035 4258 4126 359 3004 3141 3815
New Hampshire 2514 2721 2671 2403 1919 2564 2128
Pennsylvania na na 1013 1277 1473 1876 1738
Rhode Island na na 803 812 898 949 639
West Virginia 1496 1381 1636 2384 2006 1966 1372
Kentucky 1772 1764 2741 1863 2796 2682 2247
New Mexico 902 858 595 787 865 717 74
Missouri 1002 997 118 1192 1131 124 1255
Ohio na na 1804 2198 2693 3254 2165
Wisconsin 286 244 267 293 575 586 625
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 5609 6697 5845 5976 6142 7078 6936
Massachusetts na na na na na na na
New Hampshire 5678 5968 6872 5883 5394 6787 6135
Pennsylvania na na 8374 9102 9010 10100 9983
Rhode Island na na 3567 3829 3527 3880 3262
West Virginia 4628 3889 4229 5489 4642 4832 4034
Kentucky 6756 6687 7517 6234 7613 8444 7205
New Mexico 5291 6842 7036 7402 7345 7672 7123
Missouri 3213 3235 3137 3373 3383 3421 3565
Ohio na na 8696 8789 9859 11432 9300
Wisconsin 2724 2661 3031 3291 4255 4633 5064
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
15 to 24
25 to 34
35 to 54
55 and up
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Male -140 7355 827 901 1286 -927 742 -758 1157 1241 1306 -829 146 301 1082 1242 1306 -1249
Female 841 5151 103 733 1257 -1521 659 -922 533 1204 1494 -1014 -132 1299 229 1331 1617 -1214
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 4888 4820 8365 9057 9873 11142 10110
Female 3201 3470 5257 5312 5701 6418 5442
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 3611 3879 3585 40 4496 5083 4662
Female 159 1695 1538 162 1816 2087 1875
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 2295 2328 2399 2658 2988 3379 2957
Female 839 828 936 957 1085 126 1107
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017 q1 q2 q3
All drug 3948 4061 6589 6894 7458 8430 7696 889150252325 1075831326045 167997701832
Heroin 1452 1472 1571 1681 1891 2173 191 302341597796 476222826087 215786123488
Opioid 2447 2636 2429 2636 2956 3382 3088 208009807928 283004552352 271305063812
Q12016-Q12017 Q22016-Q22017 Q32016-Q32017
All drug 889150252325 1075831326045 167997701832
Heroin 302341597796 476222826087 215786123488
Opioid 208009807928 283004552352 271305063812
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Heroin 136 674 701 1251 1486 -1209
Opioid 77 -785 853 1212 1442 -868
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Heroin 1452 1472 1571 1681 1891 2173 191
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Heroin 1452 1472 1571 1681 1891 2173 191
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Opioid 77 -785 853 1212 1442 -868
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Heroin 136 674 701 1251 1486 -1209
Q12016-Q12017 Q12016-Q12017 Q12016-Q12017
Q22016-Q22017 Q22016-Q22017 Q22016-Q22017
Q32016-Q32017 Q32016-Q32017 Q32016-Q32017
Column1 Any opioid Natural and semi-synthetic opioid analgesic Methadone Synthetic opioid analgesic excluding methadone Heroin
1999 1 03 03 07
21 1 04 03 07
2001 24 12 05 03 06
32 15 08 04 07
2003 35 17 1 05 07
39 18 13 06 06
2005 43 19 15 06 07
51 23 18 09 07
2007 54 27 18 07 08
57 3 16 08 1
2009 59 31 15 1 11
62 35 15 1 1
2011 66 37 14 08 14
67 35 12 08 19
2013 74 35 11 1 27
86 38 11 18 34
2015 104 39 1 31 41
133 44 1 62 49
Page 17: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

CDCrsquos Pillars on Opioids Conducting surveillance and research

Building state local and tribal prevention efforts

Supporting healthcare providers and health systems

Partnering with public safety officials

Encouraging consumers to make safe choices about opioids raising awareness about prescription opioid misuse and overdose

Rx Summit wwwNationalRxDrugAbuseSummitorg

Enhanced State Opioid Overdose Surveillance (ESOOS) 12 states funded in September 2016 20 additional states and the

District of Columbia funded in September 2017 (through September 2019)

Strategy One Increase timeliness of non-fatal opioid overdose reporting- Use syndromic surveillance to establish an early warning system to

detect sharp increases or decreases in non-fatal opioid overdoses - Three indicators suspected all-drug opioid and heroin

Alaska California Connecticut Delaware DC Florida Georgia Illinois Indiana Kentucky Louisiana Maine Maryland Massachusetts Michigan Minnesota Missouri Nevada New Hampshire New Jersey New Mexico North Carolina Ohio Oklahoma Pennsylvania Rhode Island Tennessee Utah Vermont Virginia Washington West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

Enhanced State Opioid Overdose Surveillance (ESOOS) Strategy Two Increase timeliness of fatal opioid overdose

reporting- Capture detailed information on toxicology death scene

investigations and other risk factors that may be associated with a fatal overdose

Strategy Three widespread dissemination- Rapidly disseminate surveillance findings to key stakeholders

working to prevent or respond to opioid overdoses

ESOOS program expansion in September 2017- At least 60 for comprehensive toxicology testing for opioid-

involved deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

Funded ESOOS states

Rx Summit wwwNationalRxDrugAbuseSummitorg

Enhanced State Opioid Overdose Surveillance (ESOOS)

Nonfatal Opioid Overdoses Reported

Quarterly

Emergency Department Visits EMS Transports

Fatal Opioid Overdoses Reported within 8 months

of death

Death CertificatesMEC reports

Toxicology reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

Next Two Presentationshellip

The Utilization of Emergency Department Syndromic Surveillance and Emergency Medical Services Data to Monitor Nonfatal Opioid Overdoses ndash Dr Alana Vivolo-Kantor

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System ndash Dr Julie OrsquoDonnell

Rx Summit wwwNationalRxDrugAbuseSummitorg

The utilization of emergency department syndromic surveillance

and emergency medical services data to monitor nonfatal opioid

overdosesPresenter Alana Vivolo-Kantor PhD

Behavioral ScientistCenters for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Julie OrsquoDonnell R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Alana Vivolo-Kantor PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Why Emergency Department and Emergency Medical Service Data for Surveillance

Need- Identify areas experiencing rapid increases in opioid overdoses to

inform responses- More quickly identify promising practices to reduce opioid overdoses

Proven utility to public health and scalable- Local jurisdictions already using it to track and respond to drug

overdoses- Findings from Epi-Aid investigations and collaborative work with states- Leverage existing state and national resources (BioSenseESSENCE)

Action at local and national level- Track quarterly trends across the nation to inform national policy- Improve more rapid local and state public health response

Rx Summit wwwNationalRxDrugAbuseSummitorg

Our Philosophy

Focus on detecting change- Pushing system by looking at trend data over quarters- Some jurisdictions may be able to get and report preliminary

burden estimates

Jurisdiction-driven definitions will outperform national definitions- Local flexibility enhances quality and utility by accounting for large

variance in text entries and coding

National guidance- National definition will provide a good starting place- Guidance to encourage common conceptual definition (eg no

withdrawaldetox) and learn from previous work

Rx Summit wwwNationalRxDrugAbuseSummitorg

Our approach

Non-fatal overdoses

Emergency Department

Near real-time ED collection (ie

syndromic ESSENCE)

Case-level or aggregate data shared

through ESSENCE (BioSense) or directly

with CDC

DischargeBilling Data

Case-level or aggregate data shared

directly with CDC

Emergency Medical Services

Case-level or aggregate data shared

directly with CDC

Includes breakdown by

sex age group and county of residence

Raceethnicity is optional

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency Department Data

Two sources- Near real-time syndromic data (visit information within 24-48 hours)- Lagged hospital billing or claims data (usually within 3-4 weeks)

Different variables used- Discharge diagnosis codes (eg ICD-10-CM) ndash available in billing

data and sometimes in syndromic- Free text fields (eg chief complaint provided by Doctor) ndash

available only in syndromic

Rx Summit wwwNationalRxDrugAbuseSummitorg

Case definitions for suspected overdose

If syndromic- Uses both discharge codes (ie ICD-9-CM ICD-10-CM and

SNOMED) and free text fields such as chief complaint or triage notes

- Free text searches use common terms slang and misspellings (eg herion instead of heroin)

If hospital billing or claimshellip- Uses only discharge codes (ie ICD-9-CM ICD-10-CM and

SNOMED)

Discharge codes use are for acute unintentional or undetermined drug poisoning (eg T401X1A in ICD-10-CM) and may also include some substance useabuse codes (ie F11 in ICD-10-CM)

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency medical services data

Capture potential EMS transports to EDs- Excludes instances where individual is pronounced deceased on

the scene inter-facility transports and when EMTs provide no ldquotreatmentrdquo (eg patient refused or required no treatment or transport)

Different variables used- Chief Complaint Secondary complaint- Narrative- Provider Impression- ICD-1O-CM codes- Medication administered (ie Naloxone)- Response to medication administered (ie awake following

Naloxone administration)

Rx Summit wwwNationalRxDrugAbuseSummitorg

Challenges in EMS data

Transition to newer versions of NEMSIS- Some states working in up to three versions (v221 v334 amp

v340)

Different case definitions in different versions

Missing data feeds

Not all EMS agencies share data

Varying time frame in when data is received- lt24 hours to 6 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Data submission process

Rx Summit wwwNationalRxDrugAbuseSummitorg

Sample quality control report

ObsSTATE YEAR QUARTER ERROR_TEXTTOTAL ED VISITS (GENDER)

TOTAL ED VISITS (AGE)

1XX 2017 1 ED Visits mismatch 98287 98309

2XX 2017 2 ED Visits mismatch 98195 98230

3XX 2017 3 ED Visits mismatch 99167 99205

Rx Summit wwwNationalRxDrugAbuseSummitorg

Sample site report

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results All drug (11 sites)

0

10

20

30

40

50

60

70

80

90

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d al

l dru

g ov

erdo

se ra

tes

by

100

00 E

D v

isits

Quarter year

-2000

-1000

000

1000

2000

3000

4000

5000

6000

7000

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Opioid (11 sites)

0

5

10

15

20

25

30

35

40

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Heroin (11 sites)

0

5

10

15

20

25

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-15

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

Annual percentage changes (11 sites)

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Chart1

All drug
Heroin
Opioid
889150252325
302341597796
208009807928
1075831326045
476222826087
283004552352
167997701832
215786123488
271305063812

table with overall

table with overall

All drug
Suspected all drug overdose rates by 10000 ED visits

Sheet1

All drug

table by sex

Opioid
Quarter year
Suspected opioid overdose rates by 10000 ED visits

table by age

Opioid

table by state

Heroin
Quarter year
Suspected opioid overdose rates by 10000 ED visits
Heroin
All drug
Heroin
Opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Summary

Stable increases for all drug and heroin from Q1 2016 to Q3 2017- Opioid had stable increases from Q3 2016 to Q2 2017

Moderate decreases from Q2 to Q3 2017- 9 for all drug 9 for opioid and 12 for heroin

Annual percentage changes were above 15 increases- Q1 to Q1 89 all drug 30 heroin amp 21 opioid- Q2 to Q2 108 all drug 48 heroin amp 28 opioid- Q3 to Q3 17 all drug 22 heroin amp 27 opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency department data dissemination efforts

ldquoOpioid Overdoses Treated in Emergency Departmentsrdquo -httpswwwcdcgovvitalsignsopioid-overdosesindexhtml

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose

Reporting System

Presenter Julie OrsquoDonnell PhD MPHEpidemiologist

Centers for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Alana Vivolo-Kantor R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Julie OrsquoDonnell PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Increase in deaths outpaces increase in use

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid

overdose

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid overdose surveillance

Track specific substances contributing to overdose deaths

Detect newly-emerging substances involved in overdose

Determine risk factors circumstances associated with fatal overdose

Assess common drug combinations Provide more timely data on overdose deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

State Unintentional Drug Overdose Reporting System (SUDORS)

Death certificates

Medical examiner

coroner reportsToxicology

reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data submitted bi-annually

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

1 Data entry started

2 Data entry finished

1 Data entry started

2 Data entry finished

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS leverages National Violent Death Reporting System (NVDRS) platform

- Basic descriptors- Compare across demographics

- Recent release from institution- Overdose location - Survival time

- Mental health diagnoses- Substance abuse treatment history

- Substances present- Substances contributing to death

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Maine 1941 -1273 225 278 1523 -201 3951 -692 257 -813 2945 981 793 656 -299 -2255 3199 2197
Massachusetts na na na na na na 1561 -157 -848 -1148 311 1897 553 -31 -13 -1632 456 2146
New Hampshire 511 1514 -1438 -832 2583 -961 318 64 -433 -1791 2967 -876 825 -184 -1002 -2016 3363 -17
Pennsylvania na na 869 -102 1211 -116 na na 2979 1751 2589 -594 na na 2601 1534 2735 -735
Rhode Island na na 735 -790 1002 -1594 na na 28 454 544 -1191 na na 121 1057 566 -3262
West Virginia -1596 875 2978 -1543 409 -1651 -367 995 4331 -1664 402 -2377 -769 1847 4571 -1584 -199 -3022
Kentucky -102 1242 -1707 2211 1092 -1468 1095 5192 -2694 4045 352 -2002 -043 5541 -3206 5012 -408 -1624
New Mexico 2932 283 521 -078 445 -716 255 -1298 2611 151 -501 -1093 -487 -3061 3227 987 -1715 323
Missouri 068 -304 754 028 114 421 292 827 477 -177 954 767 -046 1839 096 -512 966 125
Ohio na na 107 1216 1596 -1865 na na 2274 2567 2167 -3194 na na 2182 2254 2086 -3348
Wisconsin -229 1388 861 2928 888 931 -948 986 1712 6728 322 314 -1457 91 983 9621 196 668
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 1514 2112 1966 2017 1853 2398 2634
Massachusetts 7036 8133 8006 7327 6486 6687 7956
New Hampshire 3806 3927 4179 3998 3282 4255 3882
Pennsylvania na na 1265 1641 1929 2428 2284
Rhode Island na na 1498 154 161 1698 1496
West Virginia 2258 2176 2392 3428 2857 2972 2266
Kentucky 2095 2325 3532 258 3624 3752 3001
New Mexico 1927 1976 1719 2168 2201 2091 1862
Missouri 1472 1515 1641 1719 1688 185 1991
Ohio na na 236 2897 3641 443 3015
Wisconsin 664 601 66 773 1294 1336 1377
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 502 9 959 931 721 952 1161
Massachusetts 4035 4258 4126 359 3004 3141 3815
New Hampshire 2514 2721 2671 2403 1919 2564 2128
Pennsylvania na na 1013 1277 1473 1876 1738
Rhode Island na na 803 812 898 949 639
West Virginia 1496 1381 1636 2384 2006 1966 1372
Kentucky 1772 1764 2741 1863 2796 2682 2247
New Mexico 902 858 595 787 865 717 74
Missouri 1002 997 118 1192 1131 124 1255
Ohio na na 1804 2198 2693 3254 2165
Wisconsin 286 244 267 293 575 586 625
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 5609 6697 5845 5976 6142 7078 6936
Massachusetts na na na na na na na
New Hampshire 5678 5968 6872 5883 5394 6787 6135
Pennsylvania na na 8374 9102 9010 10100 9983
Rhode Island na na 3567 3829 3527 3880 3262
West Virginia 4628 3889 4229 5489 4642 4832 4034
Kentucky 6756 6687 7517 6234 7613 8444 7205
New Mexico 5291 6842 7036 7402 7345 7672 7123
Missouri 3213 3235 3137 3373 3383 3421 3565
Ohio na na 8696 8789 9859 11432 9300
Wisconsin 2724 2661 3031 3291 4255 4633 5064
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
15 to 24
25 to 34
35 to 54
55 and up
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Male -140 7355 827 901 1286 -927 742 -758 1157 1241 1306 -829 146 301 1082 1242 1306 -1249
Female 841 5151 103 733 1257 -1521 659 -922 533 1204 1494 -1014 -132 1299 229 1331 1617 -1214
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 4888 4820 8365 9057 9873 11142 10110
Female 3201 3470 5257 5312 5701 6418 5442
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 3611 3879 3585 40 4496 5083 4662
Female 159 1695 1538 162 1816 2087 1875
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 2295 2328 2399 2658 2988 3379 2957
Female 839 828 936 957 1085 126 1107
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017 q1 q2 q3
All drug 3948 4061 6589 6894 7458 8430 7696 889150252325 1075831326045 167997701832
Heroin 1452 1472 1571 1681 1891 2173 191 302341597796 476222826087 215786123488
Opioid 2447 2636 2429 2636 2956 3382 3088 208009807928 283004552352 271305063812
Q12016-Q12017 Q22016-Q22017 Q32016-Q32017
All drug 889150252325 1075831326045 167997701832
Heroin 302341597796 476222826087 215786123488
Opioid 208009807928 283004552352 271305063812
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Heroin 136 674 701 1251 1486 -1209
Opioid 77 -785 853 1212 1442 -868
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Heroin 1452 1472 1571 1681 1891 2173 191
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Heroin 1452 1472 1571 1681 1891 2173 191
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Opioid 77 -785 853 1212 1442 -868
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Heroin 136 674 701 1251 1486 -1209
Q12016-Q12017 Q12016-Q12017 Q12016-Q12017
Q22016-Q22017 Q22016-Q22017 Q22016-Q22017
Q32016-Q32017 Q32016-Q32017 Q32016-Q32017
Page 18: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

Enhanced State Opioid Overdose Surveillance (ESOOS) 12 states funded in September 2016 20 additional states and the

District of Columbia funded in September 2017 (through September 2019)

Strategy One Increase timeliness of non-fatal opioid overdose reporting- Use syndromic surveillance to establish an early warning system to

detect sharp increases or decreases in non-fatal opioid overdoses - Three indicators suspected all-drug opioid and heroin

Alaska California Connecticut Delaware DC Florida Georgia Illinois Indiana Kentucky Louisiana Maine Maryland Massachusetts Michigan Minnesota Missouri Nevada New Hampshire New Jersey New Mexico North Carolina Ohio Oklahoma Pennsylvania Rhode Island Tennessee Utah Vermont Virginia Washington West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

Enhanced State Opioid Overdose Surveillance (ESOOS) Strategy Two Increase timeliness of fatal opioid overdose

reporting- Capture detailed information on toxicology death scene

investigations and other risk factors that may be associated with a fatal overdose

Strategy Three widespread dissemination- Rapidly disseminate surveillance findings to key stakeholders

working to prevent or respond to opioid overdoses

ESOOS program expansion in September 2017- At least 60 for comprehensive toxicology testing for opioid-

involved deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

Funded ESOOS states

Rx Summit wwwNationalRxDrugAbuseSummitorg

Enhanced State Opioid Overdose Surveillance (ESOOS)

Nonfatal Opioid Overdoses Reported

Quarterly

Emergency Department Visits EMS Transports

Fatal Opioid Overdoses Reported within 8 months

of death

Death CertificatesMEC reports

Toxicology reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

Next Two Presentationshellip

The Utilization of Emergency Department Syndromic Surveillance and Emergency Medical Services Data to Monitor Nonfatal Opioid Overdoses ndash Dr Alana Vivolo-Kantor

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System ndash Dr Julie OrsquoDonnell

Rx Summit wwwNationalRxDrugAbuseSummitorg

The utilization of emergency department syndromic surveillance

and emergency medical services data to monitor nonfatal opioid

overdosesPresenter Alana Vivolo-Kantor PhD

Behavioral ScientistCenters for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Julie OrsquoDonnell R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Alana Vivolo-Kantor PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Why Emergency Department and Emergency Medical Service Data for Surveillance

Need- Identify areas experiencing rapid increases in opioid overdoses to

inform responses- More quickly identify promising practices to reduce opioid overdoses

Proven utility to public health and scalable- Local jurisdictions already using it to track and respond to drug

overdoses- Findings from Epi-Aid investigations and collaborative work with states- Leverage existing state and national resources (BioSenseESSENCE)

Action at local and national level- Track quarterly trends across the nation to inform national policy- Improve more rapid local and state public health response

Rx Summit wwwNationalRxDrugAbuseSummitorg

Our Philosophy

Focus on detecting change- Pushing system by looking at trend data over quarters- Some jurisdictions may be able to get and report preliminary

burden estimates

Jurisdiction-driven definitions will outperform national definitions- Local flexibility enhances quality and utility by accounting for large

variance in text entries and coding

National guidance- National definition will provide a good starting place- Guidance to encourage common conceptual definition (eg no

withdrawaldetox) and learn from previous work

Rx Summit wwwNationalRxDrugAbuseSummitorg

Our approach

Non-fatal overdoses

Emergency Department

Near real-time ED collection (ie

syndromic ESSENCE)

Case-level or aggregate data shared

through ESSENCE (BioSense) or directly

with CDC

DischargeBilling Data

Case-level or aggregate data shared

directly with CDC

Emergency Medical Services

Case-level or aggregate data shared

directly with CDC

Includes breakdown by

sex age group and county of residence

Raceethnicity is optional

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency Department Data

Two sources- Near real-time syndromic data (visit information within 24-48 hours)- Lagged hospital billing or claims data (usually within 3-4 weeks)

Different variables used- Discharge diagnosis codes (eg ICD-10-CM) ndash available in billing

data and sometimes in syndromic- Free text fields (eg chief complaint provided by Doctor) ndash

available only in syndromic

Rx Summit wwwNationalRxDrugAbuseSummitorg

Case definitions for suspected overdose

If syndromic- Uses both discharge codes (ie ICD-9-CM ICD-10-CM and

SNOMED) and free text fields such as chief complaint or triage notes

- Free text searches use common terms slang and misspellings (eg herion instead of heroin)

If hospital billing or claimshellip- Uses only discharge codes (ie ICD-9-CM ICD-10-CM and

SNOMED)

Discharge codes use are for acute unintentional or undetermined drug poisoning (eg T401X1A in ICD-10-CM) and may also include some substance useabuse codes (ie F11 in ICD-10-CM)

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency medical services data

Capture potential EMS transports to EDs- Excludes instances where individual is pronounced deceased on

the scene inter-facility transports and when EMTs provide no ldquotreatmentrdquo (eg patient refused or required no treatment or transport)

Different variables used- Chief Complaint Secondary complaint- Narrative- Provider Impression- ICD-1O-CM codes- Medication administered (ie Naloxone)- Response to medication administered (ie awake following

Naloxone administration)

Rx Summit wwwNationalRxDrugAbuseSummitorg

Challenges in EMS data

Transition to newer versions of NEMSIS- Some states working in up to three versions (v221 v334 amp

v340)

Different case definitions in different versions

Missing data feeds

Not all EMS agencies share data

Varying time frame in when data is received- lt24 hours to 6 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Data submission process

Rx Summit wwwNationalRxDrugAbuseSummitorg

Sample quality control report

ObsSTATE YEAR QUARTER ERROR_TEXTTOTAL ED VISITS (GENDER)

TOTAL ED VISITS (AGE)

1XX 2017 1 ED Visits mismatch 98287 98309

2XX 2017 2 ED Visits mismatch 98195 98230

3XX 2017 3 ED Visits mismatch 99167 99205

Rx Summit wwwNationalRxDrugAbuseSummitorg

Sample site report

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results All drug (11 sites)

0

10

20

30

40

50

60

70

80

90

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d al

l dru

g ov

erdo

se ra

tes

by

100

00 E

D v

isits

Quarter year

-2000

-1000

000

1000

2000

3000

4000

5000

6000

7000

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Opioid (11 sites)

0

5

10

15

20

25

30

35

40

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Heroin (11 sites)

0

5

10

15

20

25

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-15

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

Annual percentage changes (11 sites)

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Chart1

All drug
Heroin
Opioid
889150252325
302341597796
208009807928
1075831326045
476222826087
283004552352
167997701832
215786123488
271305063812

table with overall

table with overall

All drug
Suspected all drug overdose rates by 10000 ED visits

Sheet1

All drug

table by sex

Opioid
Quarter year
Suspected opioid overdose rates by 10000 ED visits

table by age

Opioid

table by state

Heroin
Quarter year
Suspected opioid overdose rates by 10000 ED visits
Heroin
All drug
Heroin
Opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Summary

Stable increases for all drug and heroin from Q1 2016 to Q3 2017- Opioid had stable increases from Q3 2016 to Q2 2017

Moderate decreases from Q2 to Q3 2017- 9 for all drug 9 for opioid and 12 for heroin

Annual percentage changes were above 15 increases- Q1 to Q1 89 all drug 30 heroin amp 21 opioid- Q2 to Q2 108 all drug 48 heroin amp 28 opioid- Q3 to Q3 17 all drug 22 heroin amp 27 opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency department data dissemination efforts

ldquoOpioid Overdoses Treated in Emergency Departmentsrdquo -httpswwwcdcgovvitalsignsopioid-overdosesindexhtml

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose

Reporting System

Presenter Julie OrsquoDonnell PhD MPHEpidemiologist

Centers for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Alana Vivolo-Kantor R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Julie OrsquoDonnell PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Increase in deaths outpaces increase in use

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid

overdose

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid overdose surveillance

Track specific substances contributing to overdose deaths

Detect newly-emerging substances involved in overdose

Determine risk factors circumstances associated with fatal overdose

Assess common drug combinations Provide more timely data on overdose deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

State Unintentional Drug Overdose Reporting System (SUDORS)

Death certificates

Medical examiner

coroner reportsToxicology

reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data submitted bi-annually

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

1 Data entry started

2 Data entry finished

1 Data entry started

2 Data entry finished

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS leverages National Violent Death Reporting System (NVDRS) platform

- Basic descriptors- Compare across demographics

- Recent release from institution- Overdose location - Survival time

- Mental health diagnoses- Substance abuse treatment history

- Substances present- Substances contributing to death

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Maine 1941 -1273 225 278 1523 -201 3951 -692 257 -813 2945 981 793 656 -299 -2255 3199 2197
Massachusetts na na na na na na 1561 -157 -848 -1148 311 1897 553 -31 -13 -1632 456 2146
New Hampshire 511 1514 -1438 -832 2583 -961 318 64 -433 -1791 2967 -876 825 -184 -1002 -2016 3363 -17
Pennsylvania na na 869 -102 1211 -116 na na 2979 1751 2589 -594 na na 2601 1534 2735 -735
Rhode Island na na 735 -790 1002 -1594 na na 28 454 544 -1191 na na 121 1057 566 -3262
West Virginia -1596 875 2978 -1543 409 -1651 -367 995 4331 -1664 402 -2377 -769 1847 4571 -1584 -199 -3022
Kentucky -102 1242 -1707 2211 1092 -1468 1095 5192 -2694 4045 352 -2002 -043 5541 -3206 5012 -408 -1624
New Mexico 2932 283 521 -078 445 -716 255 -1298 2611 151 -501 -1093 -487 -3061 3227 987 -1715 323
Missouri 068 -304 754 028 114 421 292 827 477 -177 954 767 -046 1839 096 -512 966 125
Ohio na na 107 1216 1596 -1865 na na 2274 2567 2167 -3194 na na 2182 2254 2086 -3348
Wisconsin -229 1388 861 2928 888 931 -948 986 1712 6728 322 314 -1457 91 983 9621 196 668
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 1514 2112 1966 2017 1853 2398 2634
Massachusetts 7036 8133 8006 7327 6486 6687 7956
New Hampshire 3806 3927 4179 3998 3282 4255 3882
Pennsylvania na na 1265 1641 1929 2428 2284
Rhode Island na na 1498 154 161 1698 1496
West Virginia 2258 2176 2392 3428 2857 2972 2266
Kentucky 2095 2325 3532 258 3624 3752 3001
New Mexico 1927 1976 1719 2168 2201 2091 1862
Missouri 1472 1515 1641 1719 1688 185 1991
Ohio na na 236 2897 3641 443 3015
Wisconsin 664 601 66 773 1294 1336 1377
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 502 9 959 931 721 952 1161
Massachusetts 4035 4258 4126 359 3004 3141 3815
New Hampshire 2514 2721 2671 2403 1919 2564 2128
Pennsylvania na na 1013 1277 1473 1876 1738
Rhode Island na na 803 812 898 949 639
West Virginia 1496 1381 1636 2384 2006 1966 1372
Kentucky 1772 1764 2741 1863 2796 2682 2247
New Mexico 902 858 595 787 865 717 74
Missouri 1002 997 118 1192 1131 124 1255
Ohio na na 1804 2198 2693 3254 2165
Wisconsin 286 244 267 293 575 586 625
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 5609 6697 5845 5976 6142 7078 6936
Massachusetts na na na na na na na
New Hampshire 5678 5968 6872 5883 5394 6787 6135
Pennsylvania na na 8374 9102 9010 10100 9983
Rhode Island na na 3567 3829 3527 3880 3262
West Virginia 4628 3889 4229 5489 4642 4832 4034
Kentucky 6756 6687 7517 6234 7613 8444 7205
New Mexico 5291 6842 7036 7402 7345 7672 7123
Missouri 3213 3235 3137 3373 3383 3421 3565
Ohio na na 8696 8789 9859 11432 9300
Wisconsin 2724 2661 3031 3291 4255 4633 5064
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
15 to 24
25 to 34
35 to 54
55 and up
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Male -140 7355 827 901 1286 -927 742 -758 1157 1241 1306 -829 146 301 1082 1242 1306 -1249
Female 841 5151 103 733 1257 -1521 659 -922 533 1204 1494 -1014 -132 1299 229 1331 1617 -1214
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 4888 4820 8365 9057 9873 11142 10110
Female 3201 3470 5257 5312 5701 6418 5442
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 3611 3879 3585 40 4496 5083 4662
Female 159 1695 1538 162 1816 2087 1875
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 2295 2328 2399 2658 2988 3379 2957
Female 839 828 936 957 1085 126 1107
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017 q1 q2 q3
All drug 3948 4061 6589 6894 7458 8430 7696 889150252325 1075831326045 167997701832
Heroin 1452 1472 1571 1681 1891 2173 191 302341597796 476222826087 215786123488
Opioid 2447 2636 2429 2636 2956 3382 3088 208009807928 283004552352 271305063812
Q12016-Q12017 Q22016-Q22017 Q32016-Q32017
All drug 889150252325 1075831326045 167997701832
Heroin 302341597796 476222826087 215786123488
Opioid 208009807928 283004552352 271305063812
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Heroin 136 674 701 1251 1486 -1209
Opioid 77 -785 853 1212 1442 -868
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Heroin 1452 1472 1571 1681 1891 2173 191
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Heroin 1452 1472 1571 1681 1891 2173 191
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Opioid 77 -785 853 1212 1442 -868
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Heroin 136 674 701 1251 1486 -1209
Q12016-Q12017 Q12016-Q12017 Q12016-Q12017
Q22016-Q22017 Q22016-Q22017 Q22016-Q22017
Q32016-Q32017 Q32016-Q32017 Q32016-Q32017
Page 19: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

Enhanced State Opioid Overdose Surveillance (ESOOS) Strategy Two Increase timeliness of fatal opioid overdose

reporting- Capture detailed information on toxicology death scene

investigations and other risk factors that may be associated with a fatal overdose

Strategy Three widespread dissemination- Rapidly disseminate surveillance findings to key stakeholders

working to prevent or respond to opioid overdoses

ESOOS program expansion in September 2017- At least 60 for comprehensive toxicology testing for opioid-

involved deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

Funded ESOOS states

Rx Summit wwwNationalRxDrugAbuseSummitorg

Enhanced State Opioid Overdose Surveillance (ESOOS)

Nonfatal Opioid Overdoses Reported

Quarterly

Emergency Department Visits EMS Transports

Fatal Opioid Overdoses Reported within 8 months

of death

Death CertificatesMEC reports

Toxicology reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

Next Two Presentationshellip

The Utilization of Emergency Department Syndromic Surveillance and Emergency Medical Services Data to Monitor Nonfatal Opioid Overdoses ndash Dr Alana Vivolo-Kantor

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System ndash Dr Julie OrsquoDonnell

Rx Summit wwwNationalRxDrugAbuseSummitorg

The utilization of emergency department syndromic surveillance

and emergency medical services data to monitor nonfatal opioid

overdosesPresenter Alana Vivolo-Kantor PhD

Behavioral ScientistCenters for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Julie OrsquoDonnell R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Alana Vivolo-Kantor PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Why Emergency Department and Emergency Medical Service Data for Surveillance

Need- Identify areas experiencing rapid increases in opioid overdoses to

inform responses- More quickly identify promising practices to reduce opioid overdoses

Proven utility to public health and scalable- Local jurisdictions already using it to track and respond to drug

overdoses- Findings from Epi-Aid investigations and collaborative work with states- Leverage existing state and national resources (BioSenseESSENCE)

Action at local and national level- Track quarterly trends across the nation to inform national policy- Improve more rapid local and state public health response

Rx Summit wwwNationalRxDrugAbuseSummitorg

Our Philosophy

Focus on detecting change- Pushing system by looking at trend data over quarters- Some jurisdictions may be able to get and report preliminary

burden estimates

Jurisdiction-driven definitions will outperform national definitions- Local flexibility enhances quality and utility by accounting for large

variance in text entries and coding

National guidance- National definition will provide a good starting place- Guidance to encourage common conceptual definition (eg no

withdrawaldetox) and learn from previous work

Rx Summit wwwNationalRxDrugAbuseSummitorg

Our approach

Non-fatal overdoses

Emergency Department

Near real-time ED collection (ie

syndromic ESSENCE)

Case-level or aggregate data shared

through ESSENCE (BioSense) or directly

with CDC

DischargeBilling Data

Case-level or aggregate data shared

directly with CDC

Emergency Medical Services

Case-level or aggregate data shared

directly with CDC

Includes breakdown by

sex age group and county of residence

Raceethnicity is optional

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency Department Data

Two sources- Near real-time syndromic data (visit information within 24-48 hours)- Lagged hospital billing or claims data (usually within 3-4 weeks)

Different variables used- Discharge diagnosis codes (eg ICD-10-CM) ndash available in billing

data and sometimes in syndromic- Free text fields (eg chief complaint provided by Doctor) ndash

available only in syndromic

Rx Summit wwwNationalRxDrugAbuseSummitorg

Case definitions for suspected overdose

If syndromic- Uses both discharge codes (ie ICD-9-CM ICD-10-CM and

SNOMED) and free text fields such as chief complaint or triage notes

- Free text searches use common terms slang and misspellings (eg herion instead of heroin)

If hospital billing or claimshellip- Uses only discharge codes (ie ICD-9-CM ICD-10-CM and

SNOMED)

Discharge codes use are for acute unintentional or undetermined drug poisoning (eg T401X1A in ICD-10-CM) and may also include some substance useabuse codes (ie F11 in ICD-10-CM)

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency medical services data

Capture potential EMS transports to EDs- Excludes instances where individual is pronounced deceased on

the scene inter-facility transports and when EMTs provide no ldquotreatmentrdquo (eg patient refused or required no treatment or transport)

Different variables used- Chief Complaint Secondary complaint- Narrative- Provider Impression- ICD-1O-CM codes- Medication administered (ie Naloxone)- Response to medication administered (ie awake following

Naloxone administration)

Rx Summit wwwNationalRxDrugAbuseSummitorg

Challenges in EMS data

Transition to newer versions of NEMSIS- Some states working in up to three versions (v221 v334 amp

v340)

Different case definitions in different versions

Missing data feeds

Not all EMS agencies share data

Varying time frame in when data is received- lt24 hours to 6 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Data submission process

Rx Summit wwwNationalRxDrugAbuseSummitorg

Sample quality control report

ObsSTATE YEAR QUARTER ERROR_TEXTTOTAL ED VISITS (GENDER)

TOTAL ED VISITS (AGE)

1XX 2017 1 ED Visits mismatch 98287 98309

2XX 2017 2 ED Visits mismatch 98195 98230

3XX 2017 3 ED Visits mismatch 99167 99205

Rx Summit wwwNationalRxDrugAbuseSummitorg

Sample site report

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results All drug (11 sites)

0

10

20

30

40

50

60

70

80

90

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d al

l dru

g ov

erdo

se ra

tes

by

100

00 E

D v

isits

Quarter year

-2000

-1000

000

1000

2000

3000

4000

5000

6000

7000

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Opioid (11 sites)

0

5

10

15

20

25

30

35

40

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Heroin (11 sites)

0

5

10

15

20

25

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-15

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

Annual percentage changes (11 sites)

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Chart1

All drug
Heroin
Opioid
889150252325
302341597796
208009807928
1075831326045
476222826087
283004552352
167997701832
215786123488
271305063812

table with overall

table with overall

All drug
Suspected all drug overdose rates by 10000 ED visits

Sheet1

All drug

table by sex

Opioid
Quarter year
Suspected opioid overdose rates by 10000 ED visits

table by age

Opioid

table by state

Heroin
Quarter year
Suspected opioid overdose rates by 10000 ED visits
Heroin
All drug
Heroin
Opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Summary

Stable increases for all drug and heroin from Q1 2016 to Q3 2017- Opioid had stable increases from Q3 2016 to Q2 2017

Moderate decreases from Q2 to Q3 2017- 9 for all drug 9 for opioid and 12 for heroin

Annual percentage changes were above 15 increases- Q1 to Q1 89 all drug 30 heroin amp 21 opioid- Q2 to Q2 108 all drug 48 heroin amp 28 opioid- Q3 to Q3 17 all drug 22 heroin amp 27 opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency department data dissemination efforts

ldquoOpioid Overdoses Treated in Emergency Departmentsrdquo -httpswwwcdcgovvitalsignsopioid-overdosesindexhtml

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose

Reporting System

Presenter Julie OrsquoDonnell PhD MPHEpidemiologist

Centers for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Alana Vivolo-Kantor R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Julie OrsquoDonnell PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Increase in deaths outpaces increase in use

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid

overdose

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid overdose surveillance

Track specific substances contributing to overdose deaths

Detect newly-emerging substances involved in overdose

Determine risk factors circumstances associated with fatal overdose

Assess common drug combinations Provide more timely data on overdose deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

State Unintentional Drug Overdose Reporting System (SUDORS)

Death certificates

Medical examiner

coroner reportsToxicology

reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data submitted bi-annually

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

1 Data entry started

2 Data entry finished

1 Data entry started

2 Data entry finished

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS leverages National Violent Death Reporting System (NVDRS) platform

- Basic descriptors- Compare across demographics

- Recent release from institution- Overdose location - Survival time

- Mental health diagnoses- Substance abuse treatment history

- Substances present- Substances contributing to death

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Maine 1941 -1273 225 278 1523 -201 3951 -692 257 -813 2945 981 793 656 -299 -2255 3199 2197
Massachusetts na na na na na na 1561 -157 -848 -1148 311 1897 553 -31 -13 -1632 456 2146
New Hampshire 511 1514 -1438 -832 2583 -961 318 64 -433 -1791 2967 -876 825 -184 -1002 -2016 3363 -17
Pennsylvania na na 869 -102 1211 -116 na na 2979 1751 2589 -594 na na 2601 1534 2735 -735
Rhode Island na na 735 -790 1002 -1594 na na 28 454 544 -1191 na na 121 1057 566 -3262
West Virginia -1596 875 2978 -1543 409 -1651 -367 995 4331 -1664 402 -2377 -769 1847 4571 -1584 -199 -3022
Kentucky -102 1242 -1707 2211 1092 -1468 1095 5192 -2694 4045 352 -2002 -043 5541 -3206 5012 -408 -1624
New Mexico 2932 283 521 -078 445 -716 255 -1298 2611 151 -501 -1093 -487 -3061 3227 987 -1715 323
Missouri 068 -304 754 028 114 421 292 827 477 -177 954 767 -046 1839 096 -512 966 125
Ohio na na 107 1216 1596 -1865 na na 2274 2567 2167 -3194 na na 2182 2254 2086 -3348
Wisconsin -229 1388 861 2928 888 931 -948 986 1712 6728 322 314 -1457 91 983 9621 196 668
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 1514 2112 1966 2017 1853 2398 2634
Massachusetts 7036 8133 8006 7327 6486 6687 7956
New Hampshire 3806 3927 4179 3998 3282 4255 3882
Pennsylvania na na 1265 1641 1929 2428 2284
Rhode Island na na 1498 154 161 1698 1496
West Virginia 2258 2176 2392 3428 2857 2972 2266
Kentucky 2095 2325 3532 258 3624 3752 3001
New Mexico 1927 1976 1719 2168 2201 2091 1862
Missouri 1472 1515 1641 1719 1688 185 1991
Ohio na na 236 2897 3641 443 3015
Wisconsin 664 601 66 773 1294 1336 1377
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 502 9 959 931 721 952 1161
Massachusetts 4035 4258 4126 359 3004 3141 3815
New Hampshire 2514 2721 2671 2403 1919 2564 2128
Pennsylvania na na 1013 1277 1473 1876 1738
Rhode Island na na 803 812 898 949 639
West Virginia 1496 1381 1636 2384 2006 1966 1372
Kentucky 1772 1764 2741 1863 2796 2682 2247
New Mexico 902 858 595 787 865 717 74
Missouri 1002 997 118 1192 1131 124 1255
Ohio na na 1804 2198 2693 3254 2165
Wisconsin 286 244 267 293 575 586 625
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 5609 6697 5845 5976 6142 7078 6936
Massachusetts na na na na na na na
New Hampshire 5678 5968 6872 5883 5394 6787 6135
Pennsylvania na na 8374 9102 9010 10100 9983
Rhode Island na na 3567 3829 3527 3880 3262
West Virginia 4628 3889 4229 5489 4642 4832 4034
Kentucky 6756 6687 7517 6234 7613 8444 7205
New Mexico 5291 6842 7036 7402 7345 7672 7123
Missouri 3213 3235 3137 3373 3383 3421 3565
Ohio na na 8696 8789 9859 11432 9300
Wisconsin 2724 2661 3031 3291 4255 4633 5064
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
15 to 24
25 to 34
35 to 54
55 and up
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Male -140 7355 827 901 1286 -927 742 -758 1157 1241 1306 -829 146 301 1082 1242 1306 -1249
Female 841 5151 103 733 1257 -1521 659 -922 533 1204 1494 -1014 -132 1299 229 1331 1617 -1214
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 4888 4820 8365 9057 9873 11142 10110
Female 3201 3470 5257 5312 5701 6418 5442
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 3611 3879 3585 40 4496 5083 4662
Female 159 1695 1538 162 1816 2087 1875
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 2295 2328 2399 2658 2988 3379 2957
Female 839 828 936 957 1085 126 1107
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017 q1 q2 q3
All drug 3948 4061 6589 6894 7458 8430 7696 889150252325 1075831326045 167997701832
Heroin 1452 1472 1571 1681 1891 2173 191 302341597796 476222826087 215786123488
Opioid 2447 2636 2429 2636 2956 3382 3088 208009807928 283004552352 271305063812
Q12016-Q12017 Q22016-Q22017 Q32016-Q32017
All drug 889150252325 1075831326045 167997701832
Heroin 302341597796 476222826087 215786123488
Opioid 208009807928 283004552352 271305063812
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Heroin 136 674 701 1251 1486 -1209
Opioid 77 -785 853 1212 1442 -868
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Heroin 1452 1472 1571 1681 1891 2173 191
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Heroin 1452 1472 1571 1681 1891 2173 191
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Opioid 77 -785 853 1212 1442 -868
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Heroin 136 674 701 1251 1486 -1209
Q12016-Q12017 Q12016-Q12017 Q12016-Q12017
Q22016-Q22017 Q22016-Q22017 Q22016-Q22017
Q32016-Q32017 Q32016-Q32017 Q32016-Q32017
Page 20: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

Funded ESOOS states

Rx Summit wwwNationalRxDrugAbuseSummitorg

Enhanced State Opioid Overdose Surveillance (ESOOS)

Nonfatal Opioid Overdoses Reported

Quarterly

Emergency Department Visits EMS Transports

Fatal Opioid Overdoses Reported within 8 months

of death

Death CertificatesMEC reports

Toxicology reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

Next Two Presentationshellip

The Utilization of Emergency Department Syndromic Surveillance and Emergency Medical Services Data to Monitor Nonfatal Opioid Overdoses ndash Dr Alana Vivolo-Kantor

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System ndash Dr Julie OrsquoDonnell

Rx Summit wwwNationalRxDrugAbuseSummitorg

The utilization of emergency department syndromic surveillance

and emergency medical services data to monitor nonfatal opioid

overdosesPresenter Alana Vivolo-Kantor PhD

Behavioral ScientistCenters for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Julie OrsquoDonnell R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Alana Vivolo-Kantor PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Why Emergency Department and Emergency Medical Service Data for Surveillance

Need- Identify areas experiencing rapid increases in opioid overdoses to

inform responses- More quickly identify promising practices to reduce opioid overdoses

Proven utility to public health and scalable- Local jurisdictions already using it to track and respond to drug

overdoses- Findings from Epi-Aid investigations and collaborative work with states- Leverage existing state and national resources (BioSenseESSENCE)

Action at local and national level- Track quarterly trends across the nation to inform national policy- Improve more rapid local and state public health response

Rx Summit wwwNationalRxDrugAbuseSummitorg

Our Philosophy

Focus on detecting change- Pushing system by looking at trend data over quarters- Some jurisdictions may be able to get and report preliminary

burden estimates

Jurisdiction-driven definitions will outperform national definitions- Local flexibility enhances quality and utility by accounting for large

variance in text entries and coding

National guidance- National definition will provide a good starting place- Guidance to encourage common conceptual definition (eg no

withdrawaldetox) and learn from previous work

Rx Summit wwwNationalRxDrugAbuseSummitorg

Our approach

Non-fatal overdoses

Emergency Department

Near real-time ED collection (ie

syndromic ESSENCE)

Case-level or aggregate data shared

through ESSENCE (BioSense) or directly

with CDC

DischargeBilling Data

Case-level or aggregate data shared

directly with CDC

Emergency Medical Services

Case-level or aggregate data shared

directly with CDC

Includes breakdown by

sex age group and county of residence

Raceethnicity is optional

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency Department Data

Two sources- Near real-time syndromic data (visit information within 24-48 hours)- Lagged hospital billing or claims data (usually within 3-4 weeks)

Different variables used- Discharge diagnosis codes (eg ICD-10-CM) ndash available in billing

data and sometimes in syndromic- Free text fields (eg chief complaint provided by Doctor) ndash

available only in syndromic

Rx Summit wwwNationalRxDrugAbuseSummitorg

Case definitions for suspected overdose

If syndromic- Uses both discharge codes (ie ICD-9-CM ICD-10-CM and

SNOMED) and free text fields such as chief complaint or triage notes

- Free text searches use common terms slang and misspellings (eg herion instead of heroin)

If hospital billing or claimshellip- Uses only discharge codes (ie ICD-9-CM ICD-10-CM and

SNOMED)

Discharge codes use are for acute unintentional or undetermined drug poisoning (eg T401X1A in ICD-10-CM) and may also include some substance useabuse codes (ie F11 in ICD-10-CM)

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency medical services data

Capture potential EMS transports to EDs- Excludes instances where individual is pronounced deceased on

the scene inter-facility transports and when EMTs provide no ldquotreatmentrdquo (eg patient refused or required no treatment or transport)

Different variables used- Chief Complaint Secondary complaint- Narrative- Provider Impression- ICD-1O-CM codes- Medication administered (ie Naloxone)- Response to medication administered (ie awake following

Naloxone administration)

Rx Summit wwwNationalRxDrugAbuseSummitorg

Challenges in EMS data

Transition to newer versions of NEMSIS- Some states working in up to three versions (v221 v334 amp

v340)

Different case definitions in different versions

Missing data feeds

Not all EMS agencies share data

Varying time frame in when data is received- lt24 hours to 6 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Data submission process

Rx Summit wwwNationalRxDrugAbuseSummitorg

Sample quality control report

ObsSTATE YEAR QUARTER ERROR_TEXTTOTAL ED VISITS (GENDER)

TOTAL ED VISITS (AGE)

1XX 2017 1 ED Visits mismatch 98287 98309

2XX 2017 2 ED Visits mismatch 98195 98230

3XX 2017 3 ED Visits mismatch 99167 99205

Rx Summit wwwNationalRxDrugAbuseSummitorg

Sample site report

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results All drug (11 sites)

0

10

20

30

40

50

60

70

80

90

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d al

l dru

g ov

erdo

se ra

tes

by

100

00 E

D v

isits

Quarter year

-2000

-1000

000

1000

2000

3000

4000

5000

6000

7000

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Opioid (11 sites)

0

5

10

15

20

25

30

35

40

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Heroin (11 sites)

0

5

10

15

20

25

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-15

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

Annual percentage changes (11 sites)

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Chart1

All drug
Heroin
Opioid
889150252325
302341597796
208009807928
1075831326045
476222826087
283004552352
167997701832
215786123488
271305063812

table with overall

table with overall

All drug
Suspected all drug overdose rates by 10000 ED visits

Sheet1

All drug

table by sex

Opioid
Quarter year
Suspected opioid overdose rates by 10000 ED visits

table by age

Opioid

table by state

Heroin
Quarter year
Suspected opioid overdose rates by 10000 ED visits
Heroin
All drug
Heroin
Opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Summary

Stable increases for all drug and heroin from Q1 2016 to Q3 2017- Opioid had stable increases from Q3 2016 to Q2 2017

Moderate decreases from Q2 to Q3 2017- 9 for all drug 9 for opioid and 12 for heroin

Annual percentage changes were above 15 increases- Q1 to Q1 89 all drug 30 heroin amp 21 opioid- Q2 to Q2 108 all drug 48 heroin amp 28 opioid- Q3 to Q3 17 all drug 22 heroin amp 27 opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency department data dissemination efforts

ldquoOpioid Overdoses Treated in Emergency Departmentsrdquo -httpswwwcdcgovvitalsignsopioid-overdosesindexhtml

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose

Reporting System

Presenter Julie OrsquoDonnell PhD MPHEpidemiologist

Centers for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Alana Vivolo-Kantor R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Julie OrsquoDonnell PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Increase in deaths outpaces increase in use

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid

overdose

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid overdose surveillance

Track specific substances contributing to overdose deaths

Detect newly-emerging substances involved in overdose

Determine risk factors circumstances associated with fatal overdose

Assess common drug combinations Provide more timely data on overdose deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

State Unintentional Drug Overdose Reporting System (SUDORS)

Death certificates

Medical examiner

coroner reportsToxicology

reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data submitted bi-annually

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

1 Data entry started

2 Data entry finished

1 Data entry started

2 Data entry finished

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS leverages National Violent Death Reporting System (NVDRS) platform

- Basic descriptors- Compare across demographics

- Recent release from institution- Overdose location - Survival time

- Mental health diagnoses- Substance abuse treatment history

- Substances present- Substances contributing to death

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Maine 1941 -1273 225 278 1523 -201 3951 -692 257 -813 2945 981 793 656 -299 -2255 3199 2197
Massachusetts na na na na na na 1561 -157 -848 -1148 311 1897 553 -31 -13 -1632 456 2146
New Hampshire 511 1514 -1438 -832 2583 -961 318 64 -433 -1791 2967 -876 825 -184 -1002 -2016 3363 -17
Pennsylvania na na 869 -102 1211 -116 na na 2979 1751 2589 -594 na na 2601 1534 2735 -735
Rhode Island na na 735 -790 1002 -1594 na na 28 454 544 -1191 na na 121 1057 566 -3262
West Virginia -1596 875 2978 -1543 409 -1651 -367 995 4331 -1664 402 -2377 -769 1847 4571 -1584 -199 -3022
Kentucky -102 1242 -1707 2211 1092 -1468 1095 5192 -2694 4045 352 -2002 -043 5541 -3206 5012 -408 -1624
New Mexico 2932 283 521 -078 445 -716 255 -1298 2611 151 -501 -1093 -487 -3061 3227 987 -1715 323
Missouri 068 -304 754 028 114 421 292 827 477 -177 954 767 -046 1839 096 -512 966 125
Ohio na na 107 1216 1596 -1865 na na 2274 2567 2167 -3194 na na 2182 2254 2086 -3348
Wisconsin -229 1388 861 2928 888 931 -948 986 1712 6728 322 314 -1457 91 983 9621 196 668
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 1514 2112 1966 2017 1853 2398 2634
Massachusetts 7036 8133 8006 7327 6486 6687 7956
New Hampshire 3806 3927 4179 3998 3282 4255 3882
Pennsylvania na na 1265 1641 1929 2428 2284
Rhode Island na na 1498 154 161 1698 1496
West Virginia 2258 2176 2392 3428 2857 2972 2266
Kentucky 2095 2325 3532 258 3624 3752 3001
New Mexico 1927 1976 1719 2168 2201 2091 1862
Missouri 1472 1515 1641 1719 1688 185 1991
Ohio na na 236 2897 3641 443 3015
Wisconsin 664 601 66 773 1294 1336 1377
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 502 9 959 931 721 952 1161
Massachusetts 4035 4258 4126 359 3004 3141 3815
New Hampshire 2514 2721 2671 2403 1919 2564 2128
Pennsylvania na na 1013 1277 1473 1876 1738
Rhode Island na na 803 812 898 949 639
West Virginia 1496 1381 1636 2384 2006 1966 1372
Kentucky 1772 1764 2741 1863 2796 2682 2247
New Mexico 902 858 595 787 865 717 74
Missouri 1002 997 118 1192 1131 124 1255
Ohio na na 1804 2198 2693 3254 2165
Wisconsin 286 244 267 293 575 586 625
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 5609 6697 5845 5976 6142 7078 6936
Massachusetts na na na na na na na
New Hampshire 5678 5968 6872 5883 5394 6787 6135
Pennsylvania na na 8374 9102 9010 10100 9983
Rhode Island na na 3567 3829 3527 3880 3262
West Virginia 4628 3889 4229 5489 4642 4832 4034
Kentucky 6756 6687 7517 6234 7613 8444 7205
New Mexico 5291 6842 7036 7402 7345 7672 7123
Missouri 3213 3235 3137 3373 3383 3421 3565
Ohio na na 8696 8789 9859 11432 9300
Wisconsin 2724 2661 3031 3291 4255 4633 5064
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
15 to 24
25 to 34
35 to 54
55 and up
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Male -140 7355 827 901 1286 -927 742 -758 1157 1241 1306 -829 146 301 1082 1242 1306 -1249
Female 841 5151 103 733 1257 -1521 659 -922 533 1204 1494 -1014 -132 1299 229 1331 1617 -1214
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 4888 4820 8365 9057 9873 11142 10110
Female 3201 3470 5257 5312 5701 6418 5442
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 3611 3879 3585 40 4496 5083 4662
Female 159 1695 1538 162 1816 2087 1875
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 2295 2328 2399 2658 2988 3379 2957
Female 839 828 936 957 1085 126 1107
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017 q1 q2 q3
All drug 3948 4061 6589 6894 7458 8430 7696 889150252325 1075831326045 167997701832
Heroin 1452 1472 1571 1681 1891 2173 191 302341597796 476222826087 215786123488
Opioid 2447 2636 2429 2636 2956 3382 3088 208009807928 283004552352 271305063812
Q12016-Q12017 Q22016-Q22017 Q32016-Q32017
All drug 889150252325 1075831326045 167997701832
Heroin 302341597796 476222826087 215786123488
Opioid 208009807928 283004552352 271305063812
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Heroin 136 674 701 1251 1486 -1209
Opioid 77 -785 853 1212 1442 -868
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Heroin 1452 1472 1571 1681 1891 2173 191
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Heroin 1452 1472 1571 1681 1891 2173 191
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Opioid 77 -785 853 1212 1442 -868
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Heroin 136 674 701 1251 1486 -1209
Q12016-Q12017 Q12016-Q12017 Q12016-Q12017
Q22016-Q22017 Q22016-Q22017 Q22016-Q22017
Q32016-Q32017 Q32016-Q32017 Q32016-Q32017
Page 21: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

Enhanced State Opioid Overdose Surveillance (ESOOS)

Nonfatal Opioid Overdoses Reported

Quarterly

Emergency Department Visits EMS Transports

Fatal Opioid Overdoses Reported within 8 months

of death

Death CertificatesMEC reports

Toxicology reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

Next Two Presentationshellip

The Utilization of Emergency Department Syndromic Surveillance and Emergency Medical Services Data to Monitor Nonfatal Opioid Overdoses ndash Dr Alana Vivolo-Kantor

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System ndash Dr Julie OrsquoDonnell

Rx Summit wwwNationalRxDrugAbuseSummitorg

The utilization of emergency department syndromic surveillance

and emergency medical services data to monitor nonfatal opioid

overdosesPresenter Alana Vivolo-Kantor PhD

Behavioral ScientistCenters for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Julie OrsquoDonnell R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Alana Vivolo-Kantor PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Why Emergency Department and Emergency Medical Service Data for Surveillance

Need- Identify areas experiencing rapid increases in opioid overdoses to

inform responses- More quickly identify promising practices to reduce opioid overdoses

Proven utility to public health and scalable- Local jurisdictions already using it to track and respond to drug

overdoses- Findings from Epi-Aid investigations and collaborative work with states- Leverage existing state and national resources (BioSenseESSENCE)

Action at local and national level- Track quarterly trends across the nation to inform national policy- Improve more rapid local and state public health response

Rx Summit wwwNationalRxDrugAbuseSummitorg

Our Philosophy

Focus on detecting change- Pushing system by looking at trend data over quarters- Some jurisdictions may be able to get and report preliminary

burden estimates

Jurisdiction-driven definitions will outperform national definitions- Local flexibility enhances quality and utility by accounting for large

variance in text entries and coding

National guidance- National definition will provide a good starting place- Guidance to encourage common conceptual definition (eg no

withdrawaldetox) and learn from previous work

Rx Summit wwwNationalRxDrugAbuseSummitorg

Our approach

Non-fatal overdoses

Emergency Department

Near real-time ED collection (ie

syndromic ESSENCE)

Case-level or aggregate data shared

through ESSENCE (BioSense) or directly

with CDC

DischargeBilling Data

Case-level or aggregate data shared

directly with CDC

Emergency Medical Services

Case-level or aggregate data shared

directly with CDC

Includes breakdown by

sex age group and county of residence

Raceethnicity is optional

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency Department Data

Two sources- Near real-time syndromic data (visit information within 24-48 hours)- Lagged hospital billing or claims data (usually within 3-4 weeks)

Different variables used- Discharge diagnosis codes (eg ICD-10-CM) ndash available in billing

data and sometimes in syndromic- Free text fields (eg chief complaint provided by Doctor) ndash

available only in syndromic

Rx Summit wwwNationalRxDrugAbuseSummitorg

Case definitions for suspected overdose

If syndromic- Uses both discharge codes (ie ICD-9-CM ICD-10-CM and

SNOMED) and free text fields such as chief complaint or triage notes

- Free text searches use common terms slang and misspellings (eg herion instead of heroin)

If hospital billing or claimshellip- Uses only discharge codes (ie ICD-9-CM ICD-10-CM and

SNOMED)

Discharge codes use are for acute unintentional or undetermined drug poisoning (eg T401X1A in ICD-10-CM) and may also include some substance useabuse codes (ie F11 in ICD-10-CM)

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency medical services data

Capture potential EMS transports to EDs- Excludes instances where individual is pronounced deceased on

the scene inter-facility transports and when EMTs provide no ldquotreatmentrdquo (eg patient refused or required no treatment or transport)

Different variables used- Chief Complaint Secondary complaint- Narrative- Provider Impression- ICD-1O-CM codes- Medication administered (ie Naloxone)- Response to medication administered (ie awake following

Naloxone administration)

Rx Summit wwwNationalRxDrugAbuseSummitorg

Challenges in EMS data

Transition to newer versions of NEMSIS- Some states working in up to three versions (v221 v334 amp

v340)

Different case definitions in different versions

Missing data feeds

Not all EMS agencies share data

Varying time frame in when data is received- lt24 hours to 6 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Data submission process

Rx Summit wwwNationalRxDrugAbuseSummitorg

Sample quality control report

ObsSTATE YEAR QUARTER ERROR_TEXTTOTAL ED VISITS (GENDER)

TOTAL ED VISITS (AGE)

1XX 2017 1 ED Visits mismatch 98287 98309

2XX 2017 2 ED Visits mismatch 98195 98230

3XX 2017 3 ED Visits mismatch 99167 99205

Rx Summit wwwNationalRxDrugAbuseSummitorg

Sample site report

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results All drug (11 sites)

0

10

20

30

40

50

60

70

80

90

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d al

l dru

g ov

erdo

se ra

tes

by

100

00 E

D v

isits

Quarter year

-2000

-1000

000

1000

2000

3000

4000

5000

6000

7000

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Opioid (11 sites)

0

5

10

15

20

25

30

35

40

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Heroin (11 sites)

0

5

10

15

20

25

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-15

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

Annual percentage changes (11 sites)

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Chart1

All drug
Heroin
Opioid
889150252325
302341597796
208009807928
1075831326045
476222826087
283004552352
167997701832
215786123488
271305063812

table with overall

table with overall

All drug
Suspected all drug overdose rates by 10000 ED visits

Sheet1

All drug

table by sex

Opioid
Quarter year
Suspected opioid overdose rates by 10000 ED visits

table by age

Opioid

table by state

Heroin
Quarter year
Suspected opioid overdose rates by 10000 ED visits
Heroin
All drug
Heroin
Opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Summary

Stable increases for all drug and heroin from Q1 2016 to Q3 2017- Opioid had stable increases from Q3 2016 to Q2 2017

Moderate decreases from Q2 to Q3 2017- 9 for all drug 9 for opioid and 12 for heroin

Annual percentage changes were above 15 increases- Q1 to Q1 89 all drug 30 heroin amp 21 opioid- Q2 to Q2 108 all drug 48 heroin amp 28 opioid- Q3 to Q3 17 all drug 22 heroin amp 27 opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency department data dissemination efforts

ldquoOpioid Overdoses Treated in Emergency Departmentsrdquo -httpswwwcdcgovvitalsignsopioid-overdosesindexhtml

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose

Reporting System

Presenter Julie OrsquoDonnell PhD MPHEpidemiologist

Centers for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Alana Vivolo-Kantor R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Julie OrsquoDonnell PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Increase in deaths outpaces increase in use

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid

overdose

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid overdose surveillance

Track specific substances contributing to overdose deaths

Detect newly-emerging substances involved in overdose

Determine risk factors circumstances associated with fatal overdose

Assess common drug combinations Provide more timely data on overdose deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

State Unintentional Drug Overdose Reporting System (SUDORS)

Death certificates

Medical examiner

coroner reportsToxicology

reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data submitted bi-annually

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

1 Data entry started

2 Data entry finished

1 Data entry started

2 Data entry finished

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS leverages National Violent Death Reporting System (NVDRS) platform

- Basic descriptors- Compare across demographics

- Recent release from institution- Overdose location - Survival time

- Mental health diagnoses- Substance abuse treatment history

- Substances present- Substances contributing to death

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Maine 1941 -1273 225 278 1523 -201 3951 -692 257 -813 2945 981 793 656 -299 -2255 3199 2197
Massachusetts na na na na na na 1561 -157 -848 -1148 311 1897 553 -31 -13 -1632 456 2146
New Hampshire 511 1514 -1438 -832 2583 -961 318 64 -433 -1791 2967 -876 825 -184 -1002 -2016 3363 -17
Pennsylvania na na 869 -102 1211 -116 na na 2979 1751 2589 -594 na na 2601 1534 2735 -735
Rhode Island na na 735 -790 1002 -1594 na na 28 454 544 -1191 na na 121 1057 566 -3262
West Virginia -1596 875 2978 -1543 409 -1651 -367 995 4331 -1664 402 -2377 -769 1847 4571 -1584 -199 -3022
Kentucky -102 1242 -1707 2211 1092 -1468 1095 5192 -2694 4045 352 -2002 -043 5541 -3206 5012 -408 -1624
New Mexico 2932 283 521 -078 445 -716 255 -1298 2611 151 -501 -1093 -487 -3061 3227 987 -1715 323
Missouri 068 -304 754 028 114 421 292 827 477 -177 954 767 -046 1839 096 -512 966 125
Ohio na na 107 1216 1596 -1865 na na 2274 2567 2167 -3194 na na 2182 2254 2086 -3348
Wisconsin -229 1388 861 2928 888 931 -948 986 1712 6728 322 314 -1457 91 983 9621 196 668
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 1514 2112 1966 2017 1853 2398 2634
Massachusetts 7036 8133 8006 7327 6486 6687 7956
New Hampshire 3806 3927 4179 3998 3282 4255 3882
Pennsylvania na na 1265 1641 1929 2428 2284
Rhode Island na na 1498 154 161 1698 1496
West Virginia 2258 2176 2392 3428 2857 2972 2266
Kentucky 2095 2325 3532 258 3624 3752 3001
New Mexico 1927 1976 1719 2168 2201 2091 1862
Missouri 1472 1515 1641 1719 1688 185 1991
Ohio na na 236 2897 3641 443 3015
Wisconsin 664 601 66 773 1294 1336 1377
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 502 9 959 931 721 952 1161
Massachusetts 4035 4258 4126 359 3004 3141 3815
New Hampshire 2514 2721 2671 2403 1919 2564 2128
Pennsylvania na na 1013 1277 1473 1876 1738
Rhode Island na na 803 812 898 949 639
West Virginia 1496 1381 1636 2384 2006 1966 1372
Kentucky 1772 1764 2741 1863 2796 2682 2247
New Mexico 902 858 595 787 865 717 74
Missouri 1002 997 118 1192 1131 124 1255
Ohio na na 1804 2198 2693 3254 2165
Wisconsin 286 244 267 293 575 586 625
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 5609 6697 5845 5976 6142 7078 6936
Massachusetts na na na na na na na
New Hampshire 5678 5968 6872 5883 5394 6787 6135
Pennsylvania na na 8374 9102 9010 10100 9983
Rhode Island na na 3567 3829 3527 3880 3262
West Virginia 4628 3889 4229 5489 4642 4832 4034
Kentucky 6756 6687 7517 6234 7613 8444 7205
New Mexico 5291 6842 7036 7402 7345 7672 7123
Missouri 3213 3235 3137 3373 3383 3421 3565
Ohio na na 8696 8789 9859 11432 9300
Wisconsin 2724 2661 3031 3291 4255 4633 5064
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
15 to 24
25 to 34
35 to 54
55 and up
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Male -140 7355 827 901 1286 -927 742 -758 1157 1241 1306 -829 146 301 1082 1242 1306 -1249
Female 841 5151 103 733 1257 -1521 659 -922 533 1204 1494 -1014 -132 1299 229 1331 1617 -1214
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 4888 4820 8365 9057 9873 11142 10110
Female 3201 3470 5257 5312 5701 6418 5442
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 3611 3879 3585 40 4496 5083 4662
Female 159 1695 1538 162 1816 2087 1875
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 2295 2328 2399 2658 2988 3379 2957
Female 839 828 936 957 1085 126 1107
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017 q1 q2 q3
All drug 3948 4061 6589 6894 7458 8430 7696 889150252325 1075831326045 167997701832
Heroin 1452 1472 1571 1681 1891 2173 191 302341597796 476222826087 215786123488
Opioid 2447 2636 2429 2636 2956 3382 3088 208009807928 283004552352 271305063812
Q12016-Q12017 Q22016-Q22017 Q32016-Q32017
All drug 889150252325 1075831326045 167997701832
Heroin 302341597796 476222826087 215786123488
Opioid 208009807928 283004552352 271305063812
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Heroin 136 674 701 1251 1486 -1209
Opioid 77 -785 853 1212 1442 -868
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Heroin 1452 1472 1571 1681 1891 2173 191
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Heroin 1452 1472 1571 1681 1891 2173 191
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Opioid 77 -785 853 1212 1442 -868
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Heroin 136 674 701 1251 1486 -1209
Q12016-Q12017 Q12016-Q12017 Q12016-Q12017
Q22016-Q22017 Q22016-Q22017 Q22016-Q22017
Q32016-Q32017 Q32016-Q32017 Q32016-Q32017
Page 22: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

Next Two Presentationshellip

The Utilization of Emergency Department Syndromic Surveillance and Emergency Medical Services Data to Monitor Nonfatal Opioid Overdoses ndash Dr Alana Vivolo-Kantor

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System ndash Dr Julie OrsquoDonnell

Rx Summit wwwNationalRxDrugAbuseSummitorg

The utilization of emergency department syndromic surveillance

and emergency medical services data to monitor nonfatal opioid

overdosesPresenter Alana Vivolo-Kantor PhD

Behavioral ScientistCenters for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Julie OrsquoDonnell R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Alana Vivolo-Kantor PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Why Emergency Department and Emergency Medical Service Data for Surveillance

Need- Identify areas experiencing rapid increases in opioid overdoses to

inform responses- More quickly identify promising practices to reduce opioid overdoses

Proven utility to public health and scalable- Local jurisdictions already using it to track and respond to drug

overdoses- Findings from Epi-Aid investigations and collaborative work with states- Leverage existing state and national resources (BioSenseESSENCE)

Action at local and national level- Track quarterly trends across the nation to inform national policy- Improve more rapid local and state public health response

Rx Summit wwwNationalRxDrugAbuseSummitorg

Our Philosophy

Focus on detecting change- Pushing system by looking at trend data over quarters- Some jurisdictions may be able to get and report preliminary

burden estimates

Jurisdiction-driven definitions will outperform national definitions- Local flexibility enhances quality and utility by accounting for large

variance in text entries and coding

National guidance- National definition will provide a good starting place- Guidance to encourage common conceptual definition (eg no

withdrawaldetox) and learn from previous work

Rx Summit wwwNationalRxDrugAbuseSummitorg

Our approach

Non-fatal overdoses

Emergency Department

Near real-time ED collection (ie

syndromic ESSENCE)

Case-level or aggregate data shared

through ESSENCE (BioSense) or directly

with CDC

DischargeBilling Data

Case-level or aggregate data shared

directly with CDC

Emergency Medical Services

Case-level or aggregate data shared

directly with CDC

Includes breakdown by

sex age group and county of residence

Raceethnicity is optional

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency Department Data

Two sources- Near real-time syndromic data (visit information within 24-48 hours)- Lagged hospital billing or claims data (usually within 3-4 weeks)

Different variables used- Discharge diagnosis codes (eg ICD-10-CM) ndash available in billing

data and sometimes in syndromic- Free text fields (eg chief complaint provided by Doctor) ndash

available only in syndromic

Rx Summit wwwNationalRxDrugAbuseSummitorg

Case definitions for suspected overdose

If syndromic- Uses both discharge codes (ie ICD-9-CM ICD-10-CM and

SNOMED) and free text fields such as chief complaint or triage notes

- Free text searches use common terms slang and misspellings (eg herion instead of heroin)

If hospital billing or claimshellip- Uses only discharge codes (ie ICD-9-CM ICD-10-CM and

SNOMED)

Discharge codes use are for acute unintentional or undetermined drug poisoning (eg T401X1A in ICD-10-CM) and may also include some substance useabuse codes (ie F11 in ICD-10-CM)

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency medical services data

Capture potential EMS transports to EDs- Excludes instances where individual is pronounced deceased on

the scene inter-facility transports and when EMTs provide no ldquotreatmentrdquo (eg patient refused or required no treatment or transport)

Different variables used- Chief Complaint Secondary complaint- Narrative- Provider Impression- ICD-1O-CM codes- Medication administered (ie Naloxone)- Response to medication administered (ie awake following

Naloxone administration)

Rx Summit wwwNationalRxDrugAbuseSummitorg

Challenges in EMS data

Transition to newer versions of NEMSIS- Some states working in up to three versions (v221 v334 amp

v340)

Different case definitions in different versions

Missing data feeds

Not all EMS agencies share data

Varying time frame in when data is received- lt24 hours to 6 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Data submission process

Rx Summit wwwNationalRxDrugAbuseSummitorg

Sample quality control report

ObsSTATE YEAR QUARTER ERROR_TEXTTOTAL ED VISITS (GENDER)

TOTAL ED VISITS (AGE)

1XX 2017 1 ED Visits mismatch 98287 98309

2XX 2017 2 ED Visits mismatch 98195 98230

3XX 2017 3 ED Visits mismatch 99167 99205

Rx Summit wwwNationalRxDrugAbuseSummitorg

Sample site report

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results All drug (11 sites)

0

10

20

30

40

50

60

70

80

90

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d al

l dru

g ov

erdo

se ra

tes

by

100

00 E

D v

isits

Quarter year

-2000

-1000

000

1000

2000

3000

4000

5000

6000

7000

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Opioid (11 sites)

0

5

10

15

20

25

30

35

40

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Heroin (11 sites)

0

5

10

15

20

25

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-15

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

Annual percentage changes (11 sites)

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Chart1

All drug
Heroin
Opioid
889150252325
302341597796
208009807928
1075831326045
476222826087
283004552352
167997701832
215786123488
271305063812

table with overall

table with overall

All drug
Suspected all drug overdose rates by 10000 ED visits

Sheet1

All drug

table by sex

Opioid
Quarter year
Suspected opioid overdose rates by 10000 ED visits

table by age

Opioid

table by state

Heroin
Quarter year
Suspected opioid overdose rates by 10000 ED visits
Heroin
All drug
Heroin
Opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Summary

Stable increases for all drug and heroin from Q1 2016 to Q3 2017- Opioid had stable increases from Q3 2016 to Q2 2017

Moderate decreases from Q2 to Q3 2017- 9 for all drug 9 for opioid and 12 for heroin

Annual percentage changes were above 15 increases- Q1 to Q1 89 all drug 30 heroin amp 21 opioid- Q2 to Q2 108 all drug 48 heroin amp 28 opioid- Q3 to Q3 17 all drug 22 heroin amp 27 opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency department data dissemination efforts

ldquoOpioid Overdoses Treated in Emergency Departmentsrdquo -httpswwwcdcgovvitalsignsopioid-overdosesindexhtml

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose

Reporting System

Presenter Julie OrsquoDonnell PhD MPHEpidemiologist

Centers for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Alana Vivolo-Kantor R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Julie OrsquoDonnell PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Increase in deaths outpaces increase in use

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid

overdose

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid overdose surveillance

Track specific substances contributing to overdose deaths

Detect newly-emerging substances involved in overdose

Determine risk factors circumstances associated with fatal overdose

Assess common drug combinations Provide more timely data on overdose deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

State Unintentional Drug Overdose Reporting System (SUDORS)

Death certificates

Medical examiner

coroner reportsToxicology

reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data submitted bi-annually

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

1 Data entry started

2 Data entry finished

1 Data entry started

2 Data entry finished

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS leverages National Violent Death Reporting System (NVDRS) platform

- Basic descriptors- Compare across demographics

- Recent release from institution- Overdose location - Survival time

- Mental health diagnoses- Substance abuse treatment history

- Substances present- Substances contributing to death

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Maine 1941 -1273 225 278 1523 -201 3951 -692 257 -813 2945 981 793 656 -299 -2255 3199 2197
Massachusetts na na na na na na 1561 -157 -848 -1148 311 1897 553 -31 -13 -1632 456 2146
New Hampshire 511 1514 -1438 -832 2583 -961 318 64 -433 -1791 2967 -876 825 -184 -1002 -2016 3363 -17
Pennsylvania na na 869 -102 1211 -116 na na 2979 1751 2589 -594 na na 2601 1534 2735 -735
Rhode Island na na 735 -790 1002 -1594 na na 28 454 544 -1191 na na 121 1057 566 -3262
West Virginia -1596 875 2978 -1543 409 -1651 -367 995 4331 -1664 402 -2377 -769 1847 4571 -1584 -199 -3022
Kentucky -102 1242 -1707 2211 1092 -1468 1095 5192 -2694 4045 352 -2002 -043 5541 -3206 5012 -408 -1624
New Mexico 2932 283 521 -078 445 -716 255 -1298 2611 151 -501 -1093 -487 -3061 3227 987 -1715 323
Missouri 068 -304 754 028 114 421 292 827 477 -177 954 767 -046 1839 096 -512 966 125
Ohio na na 107 1216 1596 -1865 na na 2274 2567 2167 -3194 na na 2182 2254 2086 -3348
Wisconsin -229 1388 861 2928 888 931 -948 986 1712 6728 322 314 -1457 91 983 9621 196 668
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 1514 2112 1966 2017 1853 2398 2634
Massachusetts 7036 8133 8006 7327 6486 6687 7956
New Hampshire 3806 3927 4179 3998 3282 4255 3882
Pennsylvania na na 1265 1641 1929 2428 2284
Rhode Island na na 1498 154 161 1698 1496
West Virginia 2258 2176 2392 3428 2857 2972 2266
Kentucky 2095 2325 3532 258 3624 3752 3001
New Mexico 1927 1976 1719 2168 2201 2091 1862
Missouri 1472 1515 1641 1719 1688 185 1991
Ohio na na 236 2897 3641 443 3015
Wisconsin 664 601 66 773 1294 1336 1377
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 502 9 959 931 721 952 1161
Massachusetts 4035 4258 4126 359 3004 3141 3815
New Hampshire 2514 2721 2671 2403 1919 2564 2128
Pennsylvania na na 1013 1277 1473 1876 1738
Rhode Island na na 803 812 898 949 639
West Virginia 1496 1381 1636 2384 2006 1966 1372
Kentucky 1772 1764 2741 1863 2796 2682 2247
New Mexico 902 858 595 787 865 717 74
Missouri 1002 997 118 1192 1131 124 1255
Ohio na na 1804 2198 2693 3254 2165
Wisconsin 286 244 267 293 575 586 625
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 5609 6697 5845 5976 6142 7078 6936
Massachusetts na na na na na na na
New Hampshire 5678 5968 6872 5883 5394 6787 6135
Pennsylvania na na 8374 9102 9010 10100 9983
Rhode Island na na 3567 3829 3527 3880 3262
West Virginia 4628 3889 4229 5489 4642 4832 4034
Kentucky 6756 6687 7517 6234 7613 8444 7205
New Mexico 5291 6842 7036 7402 7345 7672 7123
Missouri 3213 3235 3137 3373 3383 3421 3565
Ohio na na 8696 8789 9859 11432 9300
Wisconsin 2724 2661 3031 3291 4255 4633 5064
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
15 to 24
25 to 34
35 to 54
55 and up
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Male -140 7355 827 901 1286 -927 742 -758 1157 1241 1306 -829 146 301 1082 1242 1306 -1249
Female 841 5151 103 733 1257 -1521 659 -922 533 1204 1494 -1014 -132 1299 229 1331 1617 -1214
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 4888 4820 8365 9057 9873 11142 10110
Female 3201 3470 5257 5312 5701 6418 5442
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 3611 3879 3585 40 4496 5083 4662
Female 159 1695 1538 162 1816 2087 1875
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 2295 2328 2399 2658 2988 3379 2957
Female 839 828 936 957 1085 126 1107
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017 q1 q2 q3
All drug 3948 4061 6589 6894 7458 8430 7696 889150252325 1075831326045 167997701832
Heroin 1452 1472 1571 1681 1891 2173 191 302341597796 476222826087 215786123488
Opioid 2447 2636 2429 2636 2956 3382 3088 208009807928 283004552352 271305063812
Q12016-Q12017 Q22016-Q22017 Q32016-Q32017
All drug 889150252325 1075831326045 167997701832
Heroin 302341597796 476222826087 215786123488
Opioid 208009807928 283004552352 271305063812
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Heroin 136 674 701 1251 1486 -1209
Opioid 77 -785 853 1212 1442 -868
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Heroin 1452 1472 1571 1681 1891 2173 191
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Heroin 1452 1472 1571 1681 1891 2173 191
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Opioid 77 -785 853 1212 1442 -868
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Heroin 136 674 701 1251 1486 -1209
Q12016-Q12017 Q12016-Q12017 Q12016-Q12017
Q22016-Q22017 Q22016-Q22017 Q22016-Q22017
Q32016-Q32017 Q32016-Q32017 Q32016-Q32017
Page 23: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

The utilization of emergency department syndromic surveillance

and emergency medical services data to monitor nonfatal opioid

overdosesPresenter Alana Vivolo-Kantor PhD

Behavioral ScientistCenters for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Julie OrsquoDonnell R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Alana Vivolo-Kantor PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Why Emergency Department and Emergency Medical Service Data for Surveillance

Need- Identify areas experiencing rapid increases in opioid overdoses to

inform responses- More quickly identify promising practices to reduce opioid overdoses

Proven utility to public health and scalable- Local jurisdictions already using it to track and respond to drug

overdoses- Findings from Epi-Aid investigations and collaborative work with states- Leverage existing state and national resources (BioSenseESSENCE)

Action at local and national level- Track quarterly trends across the nation to inform national policy- Improve more rapid local and state public health response

Rx Summit wwwNationalRxDrugAbuseSummitorg

Our Philosophy

Focus on detecting change- Pushing system by looking at trend data over quarters- Some jurisdictions may be able to get and report preliminary

burden estimates

Jurisdiction-driven definitions will outperform national definitions- Local flexibility enhances quality and utility by accounting for large

variance in text entries and coding

National guidance- National definition will provide a good starting place- Guidance to encourage common conceptual definition (eg no

withdrawaldetox) and learn from previous work

Rx Summit wwwNationalRxDrugAbuseSummitorg

Our approach

Non-fatal overdoses

Emergency Department

Near real-time ED collection (ie

syndromic ESSENCE)

Case-level or aggregate data shared

through ESSENCE (BioSense) or directly

with CDC

DischargeBilling Data

Case-level or aggregate data shared

directly with CDC

Emergency Medical Services

Case-level or aggregate data shared

directly with CDC

Includes breakdown by

sex age group and county of residence

Raceethnicity is optional

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency Department Data

Two sources- Near real-time syndromic data (visit information within 24-48 hours)- Lagged hospital billing or claims data (usually within 3-4 weeks)

Different variables used- Discharge diagnosis codes (eg ICD-10-CM) ndash available in billing

data and sometimes in syndromic- Free text fields (eg chief complaint provided by Doctor) ndash

available only in syndromic

Rx Summit wwwNationalRxDrugAbuseSummitorg

Case definitions for suspected overdose

If syndromic- Uses both discharge codes (ie ICD-9-CM ICD-10-CM and

SNOMED) and free text fields such as chief complaint or triage notes

- Free text searches use common terms slang and misspellings (eg herion instead of heroin)

If hospital billing or claimshellip- Uses only discharge codes (ie ICD-9-CM ICD-10-CM and

SNOMED)

Discharge codes use are for acute unintentional or undetermined drug poisoning (eg T401X1A in ICD-10-CM) and may also include some substance useabuse codes (ie F11 in ICD-10-CM)

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency medical services data

Capture potential EMS transports to EDs- Excludes instances where individual is pronounced deceased on

the scene inter-facility transports and when EMTs provide no ldquotreatmentrdquo (eg patient refused or required no treatment or transport)

Different variables used- Chief Complaint Secondary complaint- Narrative- Provider Impression- ICD-1O-CM codes- Medication administered (ie Naloxone)- Response to medication administered (ie awake following

Naloxone administration)

Rx Summit wwwNationalRxDrugAbuseSummitorg

Challenges in EMS data

Transition to newer versions of NEMSIS- Some states working in up to three versions (v221 v334 amp

v340)

Different case definitions in different versions

Missing data feeds

Not all EMS agencies share data

Varying time frame in when data is received- lt24 hours to 6 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Data submission process

Rx Summit wwwNationalRxDrugAbuseSummitorg

Sample quality control report

ObsSTATE YEAR QUARTER ERROR_TEXTTOTAL ED VISITS (GENDER)

TOTAL ED VISITS (AGE)

1XX 2017 1 ED Visits mismatch 98287 98309

2XX 2017 2 ED Visits mismatch 98195 98230

3XX 2017 3 ED Visits mismatch 99167 99205

Rx Summit wwwNationalRxDrugAbuseSummitorg

Sample site report

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results All drug (11 sites)

0

10

20

30

40

50

60

70

80

90

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d al

l dru

g ov

erdo

se ra

tes

by

100

00 E

D v

isits

Quarter year

-2000

-1000

000

1000

2000

3000

4000

5000

6000

7000

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Opioid (11 sites)

0

5

10

15

20

25

30

35

40

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Heroin (11 sites)

0

5

10

15

20

25

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-15

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

Annual percentage changes (11 sites)

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Chart1

All drug
Heroin
Opioid
889150252325
302341597796
208009807928
1075831326045
476222826087
283004552352
167997701832
215786123488
271305063812

table with overall

table with overall

All drug
Suspected all drug overdose rates by 10000 ED visits

Sheet1

All drug

table by sex

Opioid
Quarter year
Suspected opioid overdose rates by 10000 ED visits

table by age

Opioid

table by state

Heroin
Quarter year
Suspected opioid overdose rates by 10000 ED visits
Heroin
All drug
Heroin
Opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Summary

Stable increases for all drug and heroin from Q1 2016 to Q3 2017- Opioid had stable increases from Q3 2016 to Q2 2017

Moderate decreases from Q2 to Q3 2017- 9 for all drug 9 for opioid and 12 for heroin

Annual percentage changes were above 15 increases- Q1 to Q1 89 all drug 30 heroin amp 21 opioid- Q2 to Q2 108 all drug 48 heroin amp 28 opioid- Q3 to Q3 17 all drug 22 heroin amp 27 opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency department data dissemination efforts

ldquoOpioid Overdoses Treated in Emergency Departmentsrdquo -httpswwwcdcgovvitalsignsopioid-overdosesindexhtml

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose

Reporting System

Presenter Julie OrsquoDonnell PhD MPHEpidemiologist

Centers for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Alana Vivolo-Kantor R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Julie OrsquoDonnell PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Increase in deaths outpaces increase in use

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid

overdose

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid overdose surveillance

Track specific substances contributing to overdose deaths

Detect newly-emerging substances involved in overdose

Determine risk factors circumstances associated with fatal overdose

Assess common drug combinations Provide more timely data on overdose deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

State Unintentional Drug Overdose Reporting System (SUDORS)

Death certificates

Medical examiner

coroner reportsToxicology

reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data submitted bi-annually

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

1 Data entry started

2 Data entry finished

1 Data entry started

2 Data entry finished

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS leverages National Violent Death Reporting System (NVDRS) platform

- Basic descriptors- Compare across demographics

- Recent release from institution- Overdose location - Survival time

- Mental health diagnoses- Substance abuse treatment history

- Substances present- Substances contributing to death

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Maine 1941 -1273 225 278 1523 -201 3951 -692 257 -813 2945 981 793 656 -299 -2255 3199 2197
Massachusetts na na na na na na 1561 -157 -848 -1148 311 1897 553 -31 -13 -1632 456 2146
New Hampshire 511 1514 -1438 -832 2583 -961 318 64 -433 -1791 2967 -876 825 -184 -1002 -2016 3363 -17
Pennsylvania na na 869 -102 1211 -116 na na 2979 1751 2589 -594 na na 2601 1534 2735 -735
Rhode Island na na 735 -790 1002 -1594 na na 28 454 544 -1191 na na 121 1057 566 -3262
West Virginia -1596 875 2978 -1543 409 -1651 -367 995 4331 -1664 402 -2377 -769 1847 4571 -1584 -199 -3022
Kentucky -102 1242 -1707 2211 1092 -1468 1095 5192 -2694 4045 352 -2002 -043 5541 -3206 5012 -408 -1624
New Mexico 2932 283 521 -078 445 -716 255 -1298 2611 151 -501 -1093 -487 -3061 3227 987 -1715 323
Missouri 068 -304 754 028 114 421 292 827 477 -177 954 767 -046 1839 096 -512 966 125
Ohio na na 107 1216 1596 -1865 na na 2274 2567 2167 -3194 na na 2182 2254 2086 -3348
Wisconsin -229 1388 861 2928 888 931 -948 986 1712 6728 322 314 -1457 91 983 9621 196 668
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 1514 2112 1966 2017 1853 2398 2634
Massachusetts 7036 8133 8006 7327 6486 6687 7956
New Hampshire 3806 3927 4179 3998 3282 4255 3882
Pennsylvania na na 1265 1641 1929 2428 2284
Rhode Island na na 1498 154 161 1698 1496
West Virginia 2258 2176 2392 3428 2857 2972 2266
Kentucky 2095 2325 3532 258 3624 3752 3001
New Mexico 1927 1976 1719 2168 2201 2091 1862
Missouri 1472 1515 1641 1719 1688 185 1991
Ohio na na 236 2897 3641 443 3015
Wisconsin 664 601 66 773 1294 1336 1377
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 502 9 959 931 721 952 1161
Massachusetts 4035 4258 4126 359 3004 3141 3815
New Hampshire 2514 2721 2671 2403 1919 2564 2128
Pennsylvania na na 1013 1277 1473 1876 1738
Rhode Island na na 803 812 898 949 639
West Virginia 1496 1381 1636 2384 2006 1966 1372
Kentucky 1772 1764 2741 1863 2796 2682 2247
New Mexico 902 858 595 787 865 717 74
Missouri 1002 997 118 1192 1131 124 1255
Ohio na na 1804 2198 2693 3254 2165
Wisconsin 286 244 267 293 575 586 625
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 5609 6697 5845 5976 6142 7078 6936
Massachusetts na na na na na na na
New Hampshire 5678 5968 6872 5883 5394 6787 6135
Pennsylvania na na 8374 9102 9010 10100 9983
Rhode Island na na 3567 3829 3527 3880 3262
West Virginia 4628 3889 4229 5489 4642 4832 4034
Kentucky 6756 6687 7517 6234 7613 8444 7205
New Mexico 5291 6842 7036 7402 7345 7672 7123
Missouri 3213 3235 3137 3373 3383 3421 3565
Ohio na na 8696 8789 9859 11432 9300
Wisconsin 2724 2661 3031 3291 4255 4633 5064
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
15 to 24
25 to 34
35 to 54
55 and up
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Male -140 7355 827 901 1286 -927 742 -758 1157 1241 1306 -829 146 301 1082 1242 1306 -1249
Female 841 5151 103 733 1257 -1521 659 -922 533 1204 1494 -1014 -132 1299 229 1331 1617 -1214
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 4888 4820 8365 9057 9873 11142 10110
Female 3201 3470 5257 5312 5701 6418 5442
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 3611 3879 3585 40 4496 5083 4662
Female 159 1695 1538 162 1816 2087 1875
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 2295 2328 2399 2658 2988 3379 2957
Female 839 828 936 957 1085 126 1107
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017 q1 q2 q3
All drug 3948 4061 6589 6894 7458 8430 7696 889150252325 1075831326045 167997701832
Heroin 1452 1472 1571 1681 1891 2173 191 302341597796 476222826087 215786123488
Opioid 2447 2636 2429 2636 2956 3382 3088 208009807928 283004552352 271305063812
Q12016-Q12017 Q22016-Q22017 Q32016-Q32017
All drug 889150252325 1075831326045 167997701832
Heroin 302341597796 476222826087 215786123488
Opioid 208009807928 283004552352 271305063812
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Heroin 136 674 701 1251 1486 -1209
Opioid 77 -785 853 1212 1442 -868
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Heroin 1452 1472 1571 1681 1891 2173 191
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Heroin 1452 1472 1571 1681 1891 2173 191
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Opioid 77 -785 853 1212 1442 -868
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Heroin 136 674 701 1251 1486 -1209
Q12016-Q12017 Q12016-Q12017 Q12016-Q12017
Q22016-Q22017 Q22016-Q22017 Q22016-Q22017
Q32016-Q32017 Q32016-Q32017 Q32016-Q32017
Page 24: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Alana Vivolo-Kantor PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Why Emergency Department and Emergency Medical Service Data for Surveillance

Need- Identify areas experiencing rapid increases in opioid overdoses to

inform responses- More quickly identify promising practices to reduce opioid overdoses

Proven utility to public health and scalable- Local jurisdictions already using it to track and respond to drug

overdoses- Findings from Epi-Aid investigations and collaborative work with states- Leverage existing state and national resources (BioSenseESSENCE)

Action at local and national level- Track quarterly trends across the nation to inform national policy- Improve more rapid local and state public health response

Rx Summit wwwNationalRxDrugAbuseSummitorg

Our Philosophy

Focus on detecting change- Pushing system by looking at trend data over quarters- Some jurisdictions may be able to get and report preliminary

burden estimates

Jurisdiction-driven definitions will outperform national definitions- Local flexibility enhances quality and utility by accounting for large

variance in text entries and coding

National guidance- National definition will provide a good starting place- Guidance to encourage common conceptual definition (eg no

withdrawaldetox) and learn from previous work

Rx Summit wwwNationalRxDrugAbuseSummitorg

Our approach

Non-fatal overdoses

Emergency Department

Near real-time ED collection (ie

syndromic ESSENCE)

Case-level or aggregate data shared

through ESSENCE (BioSense) or directly

with CDC

DischargeBilling Data

Case-level or aggregate data shared

directly with CDC

Emergency Medical Services

Case-level or aggregate data shared

directly with CDC

Includes breakdown by

sex age group and county of residence

Raceethnicity is optional

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency Department Data

Two sources- Near real-time syndromic data (visit information within 24-48 hours)- Lagged hospital billing or claims data (usually within 3-4 weeks)

Different variables used- Discharge diagnosis codes (eg ICD-10-CM) ndash available in billing

data and sometimes in syndromic- Free text fields (eg chief complaint provided by Doctor) ndash

available only in syndromic

Rx Summit wwwNationalRxDrugAbuseSummitorg

Case definitions for suspected overdose

If syndromic- Uses both discharge codes (ie ICD-9-CM ICD-10-CM and

SNOMED) and free text fields such as chief complaint or triage notes

- Free text searches use common terms slang and misspellings (eg herion instead of heroin)

If hospital billing or claimshellip- Uses only discharge codes (ie ICD-9-CM ICD-10-CM and

SNOMED)

Discharge codes use are for acute unintentional or undetermined drug poisoning (eg T401X1A in ICD-10-CM) and may also include some substance useabuse codes (ie F11 in ICD-10-CM)

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency medical services data

Capture potential EMS transports to EDs- Excludes instances where individual is pronounced deceased on

the scene inter-facility transports and when EMTs provide no ldquotreatmentrdquo (eg patient refused or required no treatment or transport)

Different variables used- Chief Complaint Secondary complaint- Narrative- Provider Impression- ICD-1O-CM codes- Medication administered (ie Naloxone)- Response to medication administered (ie awake following

Naloxone administration)

Rx Summit wwwNationalRxDrugAbuseSummitorg

Challenges in EMS data

Transition to newer versions of NEMSIS- Some states working in up to three versions (v221 v334 amp

v340)

Different case definitions in different versions

Missing data feeds

Not all EMS agencies share data

Varying time frame in when data is received- lt24 hours to 6 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Data submission process

Rx Summit wwwNationalRxDrugAbuseSummitorg

Sample quality control report

ObsSTATE YEAR QUARTER ERROR_TEXTTOTAL ED VISITS (GENDER)

TOTAL ED VISITS (AGE)

1XX 2017 1 ED Visits mismatch 98287 98309

2XX 2017 2 ED Visits mismatch 98195 98230

3XX 2017 3 ED Visits mismatch 99167 99205

Rx Summit wwwNationalRxDrugAbuseSummitorg

Sample site report

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results All drug (11 sites)

0

10

20

30

40

50

60

70

80

90

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d al

l dru

g ov

erdo

se ra

tes

by

100

00 E

D v

isits

Quarter year

-2000

-1000

000

1000

2000

3000

4000

5000

6000

7000

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Opioid (11 sites)

0

5

10

15

20

25

30

35

40

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Heroin (11 sites)

0

5

10

15

20

25

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-15

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

Annual percentage changes (11 sites)

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Chart1

All drug
Heroin
Opioid
889150252325
302341597796
208009807928
1075831326045
476222826087
283004552352
167997701832
215786123488
271305063812

table with overall

table with overall

All drug
Suspected all drug overdose rates by 10000 ED visits

Sheet1

All drug

table by sex

Opioid
Quarter year
Suspected opioid overdose rates by 10000 ED visits

table by age

Opioid

table by state

Heroin
Quarter year
Suspected opioid overdose rates by 10000 ED visits
Heroin
All drug
Heroin
Opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Summary

Stable increases for all drug and heroin from Q1 2016 to Q3 2017- Opioid had stable increases from Q3 2016 to Q2 2017

Moderate decreases from Q2 to Q3 2017- 9 for all drug 9 for opioid and 12 for heroin

Annual percentage changes were above 15 increases- Q1 to Q1 89 all drug 30 heroin amp 21 opioid- Q2 to Q2 108 all drug 48 heroin amp 28 opioid- Q3 to Q3 17 all drug 22 heroin amp 27 opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency department data dissemination efforts

ldquoOpioid Overdoses Treated in Emergency Departmentsrdquo -httpswwwcdcgovvitalsignsopioid-overdosesindexhtml

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose

Reporting System

Presenter Julie OrsquoDonnell PhD MPHEpidemiologist

Centers for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Alana Vivolo-Kantor R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Julie OrsquoDonnell PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Increase in deaths outpaces increase in use

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid

overdose

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid overdose surveillance

Track specific substances contributing to overdose deaths

Detect newly-emerging substances involved in overdose

Determine risk factors circumstances associated with fatal overdose

Assess common drug combinations Provide more timely data on overdose deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

State Unintentional Drug Overdose Reporting System (SUDORS)

Death certificates

Medical examiner

coroner reportsToxicology

reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data submitted bi-annually

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

1 Data entry started

2 Data entry finished

1 Data entry started

2 Data entry finished

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS leverages National Violent Death Reporting System (NVDRS) platform

- Basic descriptors- Compare across demographics

- Recent release from institution- Overdose location - Survival time

- Mental health diagnoses- Substance abuse treatment history

- Substances present- Substances contributing to death

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Maine 1941 -1273 225 278 1523 -201 3951 -692 257 -813 2945 981 793 656 -299 -2255 3199 2197
Massachusetts na na na na na na 1561 -157 -848 -1148 311 1897 553 -31 -13 -1632 456 2146
New Hampshire 511 1514 -1438 -832 2583 -961 318 64 -433 -1791 2967 -876 825 -184 -1002 -2016 3363 -17
Pennsylvania na na 869 -102 1211 -116 na na 2979 1751 2589 -594 na na 2601 1534 2735 -735
Rhode Island na na 735 -790 1002 -1594 na na 28 454 544 -1191 na na 121 1057 566 -3262
West Virginia -1596 875 2978 -1543 409 -1651 -367 995 4331 -1664 402 -2377 -769 1847 4571 -1584 -199 -3022
Kentucky -102 1242 -1707 2211 1092 -1468 1095 5192 -2694 4045 352 -2002 -043 5541 -3206 5012 -408 -1624
New Mexico 2932 283 521 -078 445 -716 255 -1298 2611 151 -501 -1093 -487 -3061 3227 987 -1715 323
Missouri 068 -304 754 028 114 421 292 827 477 -177 954 767 -046 1839 096 -512 966 125
Ohio na na 107 1216 1596 -1865 na na 2274 2567 2167 -3194 na na 2182 2254 2086 -3348
Wisconsin -229 1388 861 2928 888 931 -948 986 1712 6728 322 314 -1457 91 983 9621 196 668
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 1514 2112 1966 2017 1853 2398 2634
Massachusetts 7036 8133 8006 7327 6486 6687 7956
New Hampshire 3806 3927 4179 3998 3282 4255 3882
Pennsylvania na na 1265 1641 1929 2428 2284
Rhode Island na na 1498 154 161 1698 1496
West Virginia 2258 2176 2392 3428 2857 2972 2266
Kentucky 2095 2325 3532 258 3624 3752 3001
New Mexico 1927 1976 1719 2168 2201 2091 1862
Missouri 1472 1515 1641 1719 1688 185 1991
Ohio na na 236 2897 3641 443 3015
Wisconsin 664 601 66 773 1294 1336 1377
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 502 9 959 931 721 952 1161
Massachusetts 4035 4258 4126 359 3004 3141 3815
New Hampshire 2514 2721 2671 2403 1919 2564 2128
Pennsylvania na na 1013 1277 1473 1876 1738
Rhode Island na na 803 812 898 949 639
West Virginia 1496 1381 1636 2384 2006 1966 1372
Kentucky 1772 1764 2741 1863 2796 2682 2247
New Mexico 902 858 595 787 865 717 74
Missouri 1002 997 118 1192 1131 124 1255
Ohio na na 1804 2198 2693 3254 2165
Wisconsin 286 244 267 293 575 586 625
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 5609 6697 5845 5976 6142 7078 6936
Massachusetts na na na na na na na
New Hampshire 5678 5968 6872 5883 5394 6787 6135
Pennsylvania na na 8374 9102 9010 10100 9983
Rhode Island na na 3567 3829 3527 3880 3262
West Virginia 4628 3889 4229 5489 4642 4832 4034
Kentucky 6756 6687 7517 6234 7613 8444 7205
New Mexico 5291 6842 7036 7402 7345 7672 7123
Missouri 3213 3235 3137 3373 3383 3421 3565
Ohio na na 8696 8789 9859 11432 9300
Wisconsin 2724 2661 3031 3291 4255 4633 5064
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
15 to 24
25 to 34
35 to 54
55 and up
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Male -140 7355 827 901 1286 -927 742 -758 1157 1241 1306 -829 146 301 1082 1242 1306 -1249
Female 841 5151 103 733 1257 -1521 659 -922 533 1204 1494 -1014 -132 1299 229 1331 1617 -1214
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 4888 4820 8365 9057 9873 11142 10110
Female 3201 3470 5257 5312 5701 6418 5442
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 3611 3879 3585 40 4496 5083 4662
Female 159 1695 1538 162 1816 2087 1875
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 2295 2328 2399 2658 2988 3379 2957
Female 839 828 936 957 1085 126 1107
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017 q1 q2 q3
All drug 3948 4061 6589 6894 7458 8430 7696 889150252325 1075831326045 167997701832
Heroin 1452 1472 1571 1681 1891 2173 191 302341597796 476222826087 215786123488
Opioid 2447 2636 2429 2636 2956 3382 3088 208009807928 283004552352 271305063812
Q12016-Q12017 Q22016-Q22017 Q32016-Q32017
All drug 889150252325 1075831326045 167997701832
Heroin 302341597796 476222826087 215786123488
Opioid 208009807928 283004552352 271305063812
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Heroin 136 674 701 1251 1486 -1209
Opioid 77 -785 853 1212 1442 -868
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Heroin 1452 1472 1571 1681 1891 2173 191
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Heroin 1452 1472 1571 1681 1891 2173 191
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Opioid 77 -785 853 1212 1442 -868
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Heroin 136 674 701 1251 1486 -1209
Q12016-Q12017 Q12016-Q12017 Q12016-Q12017
Q22016-Q22017 Q22016-Q22017 Q22016-Q22017
Q32016-Q32017 Q32016-Q32017 Q32016-Q32017
Page 25: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

Why Emergency Department and Emergency Medical Service Data for Surveillance

Need- Identify areas experiencing rapid increases in opioid overdoses to

inform responses- More quickly identify promising practices to reduce opioid overdoses

Proven utility to public health and scalable- Local jurisdictions already using it to track and respond to drug

overdoses- Findings from Epi-Aid investigations and collaborative work with states- Leverage existing state and national resources (BioSenseESSENCE)

Action at local and national level- Track quarterly trends across the nation to inform national policy- Improve more rapid local and state public health response

Rx Summit wwwNationalRxDrugAbuseSummitorg

Our Philosophy

Focus on detecting change- Pushing system by looking at trend data over quarters- Some jurisdictions may be able to get and report preliminary

burden estimates

Jurisdiction-driven definitions will outperform national definitions- Local flexibility enhances quality and utility by accounting for large

variance in text entries and coding

National guidance- National definition will provide a good starting place- Guidance to encourage common conceptual definition (eg no

withdrawaldetox) and learn from previous work

Rx Summit wwwNationalRxDrugAbuseSummitorg

Our approach

Non-fatal overdoses

Emergency Department

Near real-time ED collection (ie

syndromic ESSENCE)

Case-level or aggregate data shared

through ESSENCE (BioSense) or directly

with CDC

DischargeBilling Data

Case-level or aggregate data shared

directly with CDC

Emergency Medical Services

Case-level or aggregate data shared

directly with CDC

Includes breakdown by

sex age group and county of residence

Raceethnicity is optional

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency Department Data

Two sources- Near real-time syndromic data (visit information within 24-48 hours)- Lagged hospital billing or claims data (usually within 3-4 weeks)

Different variables used- Discharge diagnosis codes (eg ICD-10-CM) ndash available in billing

data and sometimes in syndromic- Free text fields (eg chief complaint provided by Doctor) ndash

available only in syndromic

Rx Summit wwwNationalRxDrugAbuseSummitorg

Case definitions for suspected overdose

If syndromic- Uses both discharge codes (ie ICD-9-CM ICD-10-CM and

SNOMED) and free text fields such as chief complaint or triage notes

- Free text searches use common terms slang and misspellings (eg herion instead of heroin)

If hospital billing or claimshellip- Uses only discharge codes (ie ICD-9-CM ICD-10-CM and

SNOMED)

Discharge codes use are for acute unintentional or undetermined drug poisoning (eg T401X1A in ICD-10-CM) and may also include some substance useabuse codes (ie F11 in ICD-10-CM)

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency medical services data

Capture potential EMS transports to EDs- Excludes instances where individual is pronounced deceased on

the scene inter-facility transports and when EMTs provide no ldquotreatmentrdquo (eg patient refused or required no treatment or transport)

Different variables used- Chief Complaint Secondary complaint- Narrative- Provider Impression- ICD-1O-CM codes- Medication administered (ie Naloxone)- Response to medication administered (ie awake following

Naloxone administration)

Rx Summit wwwNationalRxDrugAbuseSummitorg

Challenges in EMS data

Transition to newer versions of NEMSIS- Some states working in up to three versions (v221 v334 amp

v340)

Different case definitions in different versions

Missing data feeds

Not all EMS agencies share data

Varying time frame in when data is received- lt24 hours to 6 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Data submission process

Rx Summit wwwNationalRxDrugAbuseSummitorg

Sample quality control report

ObsSTATE YEAR QUARTER ERROR_TEXTTOTAL ED VISITS (GENDER)

TOTAL ED VISITS (AGE)

1XX 2017 1 ED Visits mismatch 98287 98309

2XX 2017 2 ED Visits mismatch 98195 98230

3XX 2017 3 ED Visits mismatch 99167 99205

Rx Summit wwwNationalRxDrugAbuseSummitorg

Sample site report

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results All drug (11 sites)

0

10

20

30

40

50

60

70

80

90

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d al

l dru

g ov

erdo

se ra

tes

by

100

00 E

D v

isits

Quarter year

-2000

-1000

000

1000

2000

3000

4000

5000

6000

7000

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Opioid (11 sites)

0

5

10

15

20

25

30

35

40

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Heroin (11 sites)

0

5

10

15

20

25

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-15

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

Annual percentage changes (11 sites)

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Chart1

All drug
Heroin
Opioid
889150252325
302341597796
208009807928
1075831326045
476222826087
283004552352
167997701832
215786123488
271305063812

table with overall

table with overall

All drug
Suspected all drug overdose rates by 10000 ED visits

Sheet1

All drug

table by sex

Opioid
Quarter year
Suspected opioid overdose rates by 10000 ED visits

table by age

Opioid

table by state

Heroin
Quarter year
Suspected opioid overdose rates by 10000 ED visits
Heroin
All drug
Heroin
Opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Summary

Stable increases for all drug and heroin from Q1 2016 to Q3 2017- Opioid had stable increases from Q3 2016 to Q2 2017

Moderate decreases from Q2 to Q3 2017- 9 for all drug 9 for opioid and 12 for heroin

Annual percentage changes were above 15 increases- Q1 to Q1 89 all drug 30 heroin amp 21 opioid- Q2 to Q2 108 all drug 48 heroin amp 28 opioid- Q3 to Q3 17 all drug 22 heroin amp 27 opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency department data dissemination efforts

ldquoOpioid Overdoses Treated in Emergency Departmentsrdquo -httpswwwcdcgovvitalsignsopioid-overdosesindexhtml

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose

Reporting System

Presenter Julie OrsquoDonnell PhD MPHEpidemiologist

Centers for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Alana Vivolo-Kantor R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Julie OrsquoDonnell PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Increase in deaths outpaces increase in use

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid

overdose

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid overdose surveillance

Track specific substances contributing to overdose deaths

Detect newly-emerging substances involved in overdose

Determine risk factors circumstances associated with fatal overdose

Assess common drug combinations Provide more timely data on overdose deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

State Unintentional Drug Overdose Reporting System (SUDORS)

Death certificates

Medical examiner

coroner reportsToxicology

reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data submitted bi-annually

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

1 Data entry started

2 Data entry finished

1 Data entry started

2 Data entry finished

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS leverages National Violent Death Reporting System (NVDRS) platform

- Basic descriptors- Compare across demographics

- Recent release from institution- Overdose location - Survival time

- Mental health diagnoses- Substance abuse treatment history

- Substances present- Substances contributing to death

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Maine 1941 -1273 225 278 1523 -201 3951 -692 257 -813 2945 981 793 656 -299 -2255 3199 2197
Massachusetts na na na na na na 1561 -157 -848 -1148 311 1897 553 -31 -13 -1632 456 2146
New Hampshire 511 1514 -1438 -832 2583 -961 318 64 -433 -1791 2967 -876 825 -184 -1002 -2016 3363 -17
Pennsylvania na na 869 -102 1211 -116 na na 2979 1751 2589 -594 na na 2601 1534 2735 -735
Rhode Island na na 735 -790 1002 -1594 na na 28 454 544 -1191 na na 121 1057 566 -3262
West Virginia -1596 875 2978 -1543 409 -1651 -367 995 4331 -1664 402 -2377 -769 1847 4571 -1584 -199 -3022
Kentucky -102 1242 -1707 2211 1092 -1468 1095 5192 -2694 4045 352 -2002 -043 5541 -3206 5012 -408 -1624
New Mexico 2932 283 521 -078 445 -716 255 -1298 2611 151 -501 -1093 -487 -3061 3227 987 -1715 323
Missouri 068 -304 754 028 114 421 292 827 477 -177 954 767 -046 1839 096 -512 966 125
Ohio na na 107 1216 1596 -1865 na na 2274 2567 2167 -3194 na na 2182 2254 2086 -3348
Wisconsin -229 1388 861 2928 888 931 -948 986 1712 6728 322 314 -1457 91 983 9621 196 668
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 1514 2112 1966 2017 1853 2398 2634
Massachusetts 7036 8133 8006 7327 6486 6687 7956
New Hampshire 3806 3927 4179 3998 3282 4255 3882
Pennsylvania na na 1265 1641 1929 2428 2284
Rhode Island na na 1498 154 161 1698 1496
West Virginia 2258 2176 2392 3428 2857 2972 2266
Kentucky 2095 2325 3532 258 3624 3752 3001
New Mexico 1927 1976 1719 2168 2201 2091 1862
Missouri 1472 1515 1641 1719 1688 185 1991
Ohio na na 236 2897 3641 443 3015
Wisconsin 664 601 66 773 1294 1336 1377
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 502 9 959 931 721 952 1161
Massachusetts 4035 4258 4126 359 3004 3141 3815
New Hampshire 2514 2721 2671 2403 1919 2564 2128
Pennsylvania na na 1013 1277 1473 1876 1738
Rhode Island na na 803 812 898 949 639
West Virginia 1496 1381 1636 2384 2006 1966 1372
Kentucky 1772 1764 2741 1863 2796 2682 2247
New Mexico 902 858 595 787 865 717 74
Missouri 1002 997 118 1192 1131 124 1255
Ohio na na 1804 2198 2693 3254 2165
Wisconsin 286 244 267 293 575 586 625
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 5609 6697 5845 5976 6142 7078 6936
Massachusetts na na na na na na na
New Hampshire 5678 5968 6872 5883 5394 6787 6135
Pennsylvania na na 8374 9102 9010 10100 9983
Rhode Island na na 3567 3829 3527 3880 3262
West Virginia 4628 3889 4229 5489 4642 4832 4034
Kentucky 6756 6687 7517 6234 7613 8444 7205
New Mexico 5291 6842 7036 7402 7345 7672 7123
Missouri 3213 3235 3137 3373 3383 3421 3565
Ohio na na 8696 8789 9859 11432 9300
Wisconsin 2724 2661 3031 3291 4255 4633 5064
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
15 to 24
25 to 34
35 to 54
55 and up
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Male -140 7355 827 901 1286 -927 742 -758 1157 1241 1306 -829 146 301 1082 1242 1306 -1249
Female 841 5151 103 733 1257 -1521 659 -922 533 1204 1494 -1014 -132 1299 229 1331 1617 -1214
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 4888 4820 8365 9057 9873 11142 10110
Female 3201 3470 5257 5312 5701 6418 5442
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 3611 3879 3585 40 4496 5083 4662
Female 159 1695 1538 162 1816 2087 1875
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 2295 2328 2399 2658 2988 3379 2957
Female 839 828 936 957 1085 126 1107
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017 q1 q2 q3
All drug 3948 4061 6589 6894 7458 8430 7696 889150252325 1075831326045 167997701832
Heroin 1452 1472 1571 1681 1891 2173 191 302341597796 476222826087 215786123488
Opioid 2447 2636 2429 2636 2956 3382 3088 208009807928 283004552352 271305063812
Q12016-Q12017 Q22016-Q22017 Q32016-Q32017
All drug 889150252325 1075831326045 167997701832
Heroin 302341597796 476222826087 215786123488
Opioid 208009807928 283004552352 271305063812
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Heroin 136 674 701 1251 1486 -1209
Opioid 77 -785 853 1212 1442 -868
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Heroin 1452 1472 1571 1681 1891 2173 191
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Heroin 1452 1472 1571 1681 1891 2173 191
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Opioid 77 -785 853 1212 1442 -868
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Heroin 136 674 701 1251 1486 -1209
Q12016-Q12017 Q12016-Q12017 Q12016-Q12017
Q22016-Q22017 Q22016-Q22017 Q22016-Q22017
Q32016-Q32017 Q32016-Q32017 Q32016-Q32017
Page 26: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

Our Philosophy

Focus on detecting change- Pushing system by looking at trend data over quarters- Some jurisdictions may be able to get and report preliminary

burden estimates

Jurisdiction-driven definitions will outperform national definitions- Local flexibility enhances quality and utility by accounting for large

variance in text entries and coding

National guidance- National definition will provide a good starting place- Guidance to encourage common conceptual definition (eg no

withdrawaldetox) and learn from previous work

Rx Summit wwwNationalRxDrugAbuseSummitorg

Our approach

Non-fatal overdoses

Emergency Department

Near real-time ED collection (ie

syndromic ESSENCE)

Case-level or aggregate data shared

through ESSENCE (BioSense) or directly

with CDC

DischargeBilling Data

Case-level or aggregate data shared

directly with CDC

Emergency Medical Services

Case-level or aggregate data shared

directly with CDC

Includes breakdown by

sex age group and county of residence

Raceethnicity is optional

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency Department Data

Two sources- Near real-time syndromic data (visit information within 24-48 hours)- Lagged hospital billing or claims data (usually within 3-4 weeks)

Different variables used- Discharge diagnosis codes (eg ICD-10-CM) ndash available in billing

data and sometimes in syndromic- Free text fields (eg chief complaint provided by Doctor) ndash

available only in syndromic

Rx Summit wwwNationalRxDrugAbuseSummitorg

Case definitions for suspected overdose

If syndromic- Uses both discharge codes (ie ICD-9-CM ICD-10-CM and

SNOMED) and free text fields such as chief complaint or triage notes

- Free text searches use common terms slang and misspellings (eg herion instead of heroin)

If hospital billing or claimshellip- Uses only discharge codes (ie ICD-9-CM ICD-10-CM and

SNOMED)

Discharge codes use are for acute unintentional or undetermined drug poisoning (eg T401X1A in ICD-10-CM) and may also include some substance useabuse codes (ie F11 in ICD-10-CM)

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency medical services data

Capture potential EMS transports to EDs- Excludes instances where individual is pronounced deceased on

the scene inter-facility transports and when EMTs provide no ldquotreatmentrdquo (eg patient refused or required no treatment or transport)

Different variables used- Chief Complaint Secondary complaint- Narrative- Provider Impression- ICD-1O-CM codes- Medication administered (ie Naloxone)- Response to medication administered (ie awake following

Naloxone administration)

Rx Summit wwwNationalRxDrugAbuseSummitorg

Challenges in EMS data

Transition to newer versions of NEMSIS- Some states working in up to three versions (v221 v334 amp

v340)

Different case definitions in different versions

Missing data feeds

Not all EMS agencies share data

Varying time frame in when data is received- lt24 hours to 6 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Data submission process

Rx Summit wwwNationalRxDrugAbuseSummitorg

Sample quality control report

ObsSTATE YEAR QUARTER ERROR_TEXTTOTAL ED VISITS (GENDER)

TOTAL ED VISITS (AGE)

1XX 2017 1 ED Visits mismatch 98287 98309

2XX 2017 2 ED Visits mismatch 98195 98230

3XX 2017 3 ED Visits mismatch 99167 99205

Rx Summit wwwNationalRxDrugAbuseSummitorg

Sample site report

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results All drug (11 sites)

0

10

20

30

40

50

60

70

80

90

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d al

l dru

g ov

erdo

se ra

tes

by

100

00 E

D v

isits

Quarter year

-2000

-1000

000

1000

2000

3000

4000

5000

6000

7000

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Opioid (11 sites)

0

5

10

15

20

25

30

35

40

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Heroin (11 sites)

0

5

10

15

20

25

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-15

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

Annual percentage changes (11 sites)

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Chart1

All drug
Heroin
Opioid
889150252325
302341597796
208009807928
1075831326045
476222826087
283004552352
167997701832
215786123488
271305063812

table with overall

table with overall

All drug
Suspected all drug overdose rates by 10000 ED visits

Sheet1

All drug

table by sex

Opioid
Quarter year
Suspected opioid overdose rates by 10000 ED visits

table by age

Opioid

table by state

Heroin
Quarter year
Suspected opioid overdose rates by 10000 ED visits
Heroin
All drug
Heroin
Opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Summary

Stable increases for all drug and heroin from Q1 2016 to Q3 2017- Opioid had stable increases from Q3 2016 to Q2 2017

Moderate decreases from Q2 to Q3 2017- 9 for all drug 9 for opioid and 12 for heroin

Annual percentage changes were above 15 increases- Q1 to Q1 89 all drug 30 heroin amp 21 opioid- Q2 to Q2 108 all drug 48 heroin amp 28 opioid- Q3 to Q3 17 all drug 22 heroin amp 27 opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency department data dissemination efforts

ldquoOpioid Overdoses Treated in Emergency Departmentsrdquo -httpswwwcdcgovvitalsignsopioid-overdosesindexhtml

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose

Reporting System

Presenter Julie OrsquoDonnell PhD MPHEpidemiologist

Centers for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Alana Vivolo-Kantor R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Julie OrsquoDonnell PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Increase in deaths outpaces increase in use

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid

overdose

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid overdose surveillance

Track specific substances contributing to overdose deaths

Detect newly-emerging substances involved in overdose

Determine risk factors circumstances associated with fatal overdose

Assess common drug combinations Provide more timely data on overdose deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

State Unintentional Drug Overdose Reporting System (SUDORS)

Death certificates

Medical examiner

coroner reportsToxicology

reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data submitted bi-annually

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

1 Data entry started

2 Data entry finished

1 Data entry started

2 Data entry finished

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS leverages National Violent Death Reporting System (NVDRS) platform

- Basic descriptors- Compare across demographics

- Recent release from institution- Overdose location - Survival time

- Mental health diagnoses- Substance abuse treatment history

- Substances present- Substances contributing to death

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Maine 1941 -1273 225 278 1523 -201 3951 -692 257 -813 2945 981 793 656 -299 -2255 3199 2197
Massachusetts na na na na na na 1561 -157 -848 -1148 311 1897 553 -31 -13 -1632 456 2146
New Hampshire 511 1514 -1438 -832 2583 -961 318 64 -433 -1791 2967 -876 825 -184 -1002 -2016 3363 -17
Pennsylvania na na 869 -102 1211 -116 na na 2979 1751 2589 -594 na na 2601 1534 2735 -735
Rhode Island na na 735 -790 1002 -1594 na na 28 454 544 -1191 na na 121 1057 566 -3262
West Virginia -1596 875 2978 -1543 409 -1651 -367 995 4331 -1664 402 -2377 -769 1847 4571 -1584 -199 -3022
Kentucky -102 1242 -1707 2211 1092 -1468 1095 5192 -2694 4045 352 -2002 -043 5541 -3206 5012 -408 -1624
New Mexico 2932 283 521 -078 445 -716 255 -1298 2611 151 -501 -1093 -487 -3061 3227 987 -1715 323
Missouri 068 -304 754 028 114 421 292 827 477 -177 954 767 -046 1839 096 -512 966 125
Ohio na na 107 1216 1596 -1865 na na 2274 2567 2167 -3194 na na 2182 2254 2086 -3348
Wisconsin -229 1388 861 2928 888 931 -948 986 1712 6728 322 314 -1457 91 983 9621 196 668
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 1514 2112 1966 2017 1853 2398 2634
Massachusetts 7036 8133 8006 7327 6486 6687 7956
New Hampshire 3806 3927 4179 3998 3282 4255 3882
Pennsylvania na na 1265 1641 1929 2428 2284
Rhode Island na na 1498 154 161 1698 1496
West Virginia 2258 2176 2392 3428 2857 2972 2266
Kentucky 2095 2325 3532 258 3624 3752 3001
New Mexico 1927 1976 1719 2168 2201 2091 1862
Missouri 1472 1515 1641 1719 1688 185 1991
Ohio na na 236 2897 3641 443 3015
Wisconsin 664 601 66 773 1294 1336 1377
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 502 9 959 931 721 952 1161
Massachusetts 4035 4258 4126 359 3004 3141 3815
New Hampshire 2514 2721 2671 2403 1919 2564 2128
Pennsylvania na na 1013 1277 1473 1876 1738
Rhode Island na na 803 812 898 949 639
West Virginia 1496 1381 1636 2384 2006 1966 1372
Kentucky 1772 1764 2741 1863 2796 2682 2247
New Mexico 902 858 595 787 865 717 74
Missouri 1002 997 118 1192 1131 124 1255
Ohio na na 1804 2198 2693 3254 2165
Wisconsin 286 244 267 293 575 586 625
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 5609 6697 5845 5976 6142 7078 6936
Massachusetts na na na na na na na
New Hampshire 5678 5968 6872 5883 5394 6787 6135
Pennsylvania na na 8374 9102 9010 10100 9983
Rhode Island na na 3567 3829 3527 3880 3262
West Virginia 4628 3889 4229 5489 4642 4832 4034
Kentucky 6756 6687 7517 6234 7613 8444 7205
New Mexico 5291 6842 7036 7402 7345 7672 7123
Missouri 3213 3235 3137 3373 3383 3421 3565
Ohio na na 8696 8789 9859 11432 9300
Wisconsin 2724 2661 3031 3291 4255 4633 5064
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
15 to 24
25 to 34
35 to 54
55 and up
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Male -140 7355 827 901 1286 -927 742 -758 1157 1241 1306 -829 146 301 1082 1242 1306 -1249
Female 841 5151 103 733 1257 -1521 659 -922 533 1204 1494 -1014 -132 1299 229 1331 1617 -1214
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 4888 4820 8365 9057 9873 11142 10110
Female 3201 3470 5257 5312 5701 6418 5442
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 3611 3879 3585 40 4496 5083 4662
Female 159 1695 1538 162 1816 2087 1875
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 2295 2328 2399 2658 2988 3379 2957
Female 839 828 936 957 1085 126 1107
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017 q1 q2 q3
All drug 3948 4061 6589 6894 7458 8430 7696 889150252325 1075831326045 167997701832
Heroin 1452 1472 1571 1681 1891 2173 191 302341597796 476222826087 215786123488
Opioid 2447 2636 2429 2636 2956 3382 3088 208009807928 283004552352 271305063812
Q12016-Q12017 Q22016-Q22017 Q32016-Q32017
All drug 889150252325 1075831326045 167997701832
Heroin 302341597796 476222826087 215786123488
Opioid 208009807928 283004552352 271305063812
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Heroin 136 674 701 1251 1486 -1209
Opioid 77 -785 853 1212 1442 -868
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Heroin 1452 1472 1571 1681 1891 2173 191
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Heroin 1452 1472 1571 1681 1891 2173 191
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Opioid 77 -785 853 1212 1442 -868
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Heroin 136 674 701 1251 1486 -1209
Q12016-Q12017 Q12016-Q12017 Q12016-Q12017
Q22016-Q22017 Q22016-Q22017 Q22016-Q22017
Q32016-Q32017 Q32016-Q32017 Q32016-Q32017
Page 27: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

Our approach

Non-fatal overdoses

Emergency Department

Near real-time ED collection (ie

syndromic ESSENCE)

Case-level or aggregate data shared

through ESSENCE (BioSense) or directly

with CDC

DischargeBilling Data

Case-level or aggregate data shared

directly with CDC

Emergency Medical Services

Case-level or aggregate data shared

directly with CDC

Includes breakdown by

sex age group and county of residence

Raceethnicity is optional

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency Department Data

Two sources- Near real-time syndromic data (visit information within 24-48 hours)- Lagged hospital billing or claims data (usually within 3-4 weeks)

Different variables used- Discharge diagnosis codes (eg ICD-10-CM) ndash available in billing

data and sometimes in syndromic- Free text fields (eg chief complaint provided by Doctor) ndash

available only in syndromic

Rx Summit wwwNationalRxDrugAbuseSummitorg

Case definitions for suspected overdose

If syndromic- Uses both discharge codes (ie ICD-9-CM ICD-10-CM and

SNOMED) and free text fields such as chief complaint or triage notes

- Free text searches use common terms slang and misspellings (eg herion instead of heroin)

If hospital billing or claimshellip- Uses only discharge codes (ie ICD-9-CM ICD-10-CM and

SNOMED)

Discharge codes use are for acute unintentional or undetermined drug poisoning (eg T401X1A in ICD-10-CM) and may also include some substance useabuse codes (ie F11 in ICD-10-CM)

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency medical services data

Capture potential EMS transports to EDs- Excludes instances where individual is pronounced deceased on

the scene inter-facility transports and when EMTs provide no ldquotreatmentrdquo (eg patient refused or required no treatment or transport)

Different variables used- Chief Complaint Secondary complaint- Narrative- Provider Impression- ICD-1O-CM codes- Medication administered (ie Naloxone)- Response to medication administered (ie awake following

Naloxone administration)

Rx Summit wwwNationalRxDrugAbuseSummitorg

Challenges in EMS data

Transition to newer versions of NEMSIS- Some states working in up to three versions (v221 v334 amp

v340)

Different case definitions in different versions

Missing data feeds

Not all EMS agencies share data

Varying time frame in when data is received- lt24 hours to 6 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Data submission process

Rx Summit wwwNationalRxDrugAbuseSummitorg

Sample quality control report

ObsSTATE YEAR QUARTER ERROR_TEXTTOTAL ED VISITS (GENDER)

TOTAL ED VISITS (AGE)

1XX 2017 1 ED Visits mismatch 98287 98309

2XX 2017 2 ED Visits mismatch 98195 98230

3XX 2017 3 ED Visits mismatch 99167 99205

Rx Summit wwwNationalRxDrugAbuseSummitorg

Sample site report

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results All drug (11 sites)

0

10

20

30

40

50

60

70

80

90

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d al

l dru

g ov

erdo

se ra

tes

by

100

00 E

D v

isits

Quarter year

-2000

-1000

000

1000

2000

3000

4000

5000

6000

7000

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Opioid (11 sites)

0

5

10

15

20

25

30

35

40

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Heroin (11 sites)

0

5

10

15

20

25

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-15

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

Annual percentage changes (11 sites)

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Chart1

All drug
Heroin
Opioid
889150252325
302341597796
208009807928
1075831326045
476222826087
283004552352
167997701832
215786123488
271305063812

table with overall

table with overall

All drug
Suspected all drug overdose rates by 10000 ED visits

Sheet1

All drug

table by sex

Opioid
Quarter year
Suspected opioid overdose rates by 10000 ED visits

table by age

Opioid

table by state

Heroin
Quarter year
Suspected opioid overdose rates by 10000 ED visits
Heroin
All drug
Heroin
Opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Summary

Stable increases for all drug and heroin from Q1 2016 to Q3 2017- Opioid had stable increases from Q3 2016 to Q2 2017

Moderate decreases from Q2 to Q3 2017- 9 for all drug 9 for opioid and 12 for heroin

Annual percentage changes were above 15 increases- Q1 to Q1 89 all drug 30 heroin amp 21 opioid- Q2 to Q2 108 all drug 48 heroin amp 28 opioid- Q3 to Q3 17 all drug 22 heroin amp 27 opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency department data dissemination efforts

ldquoOpioid Overdoses Treated in Emergency Departmentsrdquo -httpswwwcdcgovvitalsignsopioid-overdosesindexhtml

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose

Reporting System

Presenter Julie OrsquoDonnell PhD MPHEpidemiologist

Centers for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Alana Vivolo-Kantor R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Julie OrsquoDonnell PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Increase in deaths outpaces increase in use

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid

overdose

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid overdose surveillance

Track specific substances contributing to overdose deaths

Detect newly-emerging substances involved in overdose

Determine risk factors circumstances associated with fatal overdose

Assess common drug combinations Provide more timely data on overdose deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

State Unintentional Drug Overdose Reporting System (SUDORS)

Death certificates

Medical examiner

coroner reportsToxicology

reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data submitted bi-annually

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

1 Data entry started

2 Data entry finished

1 Data entry started

2 Data entry finished

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS leverages National Violent Death Reporting System (NVDRS) platform

- Basic descriptors- Compare across demographics

- Recent release from institution- Overdose location - Survival time

- Mental health diagnoses- Substance abuse treatment history

- Substances present- Substances contributing to death

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Maine 1941 -1273 225 278 1523 -201 3951 -692 257 -813 2945 981 793 656 -299 -2255 3199 2197
Massachusetts na na na na na na 1561 -157 -848 -1148 311 1897 553 -31 -13 -1632 456 2146
New Hampshire 511 1514 -1438 -832 2583 -961 318 64 -433 -1791 2967 -876 825 -184 -1002 -2016 3363 -17
Pennsylvania na na 869 -102 1211 -116 na na 2979 1751 2589 -594 na na 2601 1534 2735 -735
Rhode Island na na 735 -790 1002 -1594 na na 28 454 544 -1191 na na 121 1057 566 -3262
West Virginia -1596 875 2978 -1543 409 -1651 -367 995 4331 -1664 402 -2377 -769 1847 4571 -1584 -199 -3022
Kentucky -102 1242 -1707 2211 1092 -1468 1095 5192 -2694 4045 352 -2002 -043 5541 -3206 5012 -408 -1624
New Mexico 2932 283 521 -078 445 -716 255 -1298 2611 151 -501 -1093 -487 -3061 3227 987 -1715 323
Missouri 068 -304 754 028 114 421 292 827 477 -177 954 767 -046 1839 096 -512 966 125
Ohio na na 107 1216 1596 -1865 na na 2274 2567 2167 -3194 na na 2182 2254 2086 -3348
Wisconsin -229 1388 861 2928 888 931 -948 986 1712 6728 322 314 -1457 91 983 9621 196 668
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 1514 2112 1966 2017 1853 2398 2634
Massachusetts 7036 8133 8006 7327 6486 6687 7956
New Hampshire 3806 3927 4179 3998 3282 4255 3882
Pennsylvania na na 1265 1641 1929 2428 2284
Rhode Island na na 1498 154 161 1698 1496
West Virginia 2258 2176 2392 3428 2857 2972 2266
Kentucky 2095 2325 3532 258 3624 3752 3001
New Mexico 1927 1976 1719 2168 2201 2091 1862
Missouri 1472 1515 1641 1719 1688 185 1991
Ohio na na 236 2897 3641 443 3015
Wisconsin 664 601 66 773 1294 1336 1377
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 502 9 959 931 721 952 1161
Massachusetts 4035 4258 4126 359 3004 3141 3815
New Hampshire 2514 2721 2671 2403 1919 2564 2128
Pennsylvania na na 1013 1277 1473 1876 1738
Rhode Island na na 803 812 898 949 639
West Virginia 1496 1381 1636 2384 2006 1966 1372
Kentucky 1772 1764 2741 1863 2796 2682 2247
New Mexico 902 858 595 787 865 717 74
Missouri 1002 997 118 1192 1131 124 1255
Ohio na na 1804 2198 2693 3254 2165
Wisconsin 286 244 267 293 575 586 625
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 5609 6697 5845 5976 6142 7078 6936
Massachusetts na na na na na na na
New Hampshire 5678 5968 6872 5883 5394 6787 6135
Pennsylvania na na 8374 9102 9010 10100 9983
Rhode Island na na 3567 3829 3527 3880 3262
West Virginia 4628 3889 4229 5489 4642 4832 4034
Kentucky 6756 6687 7517 6234 7613 8444 7205
New Mexico 5291 6842 7036 7402 7345 7672 7123
Missouri 3213 3235 3137 3373 3383 3421 3565
Ohio na na 8696 8789 9859 11432 9300
Wisconsin 2724 2661 3031 3291 4255 4633 5064
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
15 to 24
25 to 34
35 to 54
55 and up
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Male -140 7355 827 901 1286 -927 742 -758 1157 1241 1306 -829 146 301 1082 1242 1306 -1249
Female 841 5151 103 733 1257 -1521 659 -922 533 1204 1494 -1014 -132 1299 229 1331 1617 -1214
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 4888 4820 8365 9057 9873 11142 10110
Female 3201 3470 5257 5312 5701 6418 5442
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 3611 3879 3585 40 4496 5083 4662
Female 159 1695 1538 162 1816 2087 1875
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 2295 2328 2399 2658 2988 3379 2957
Female 839 828 936 957 1085 126 1107
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017 q1 q2 q3
All drug 3948 4061 6589 6894 7458 8430 7696 889150252325 1075831326045 167997701832
Heroin 1452 1472 1571 1681 1891 2173 191 302341597796 476222826087 215786123488
Opioid 2447 2636 2429 2636 2956 3382 3088 208009807928 283004552352 271305063812
Q12016-Q12017 Q22016-Q22017 Q32016-Q32017
All drug 889150252325 1075831326045 167997701832
Heroin 302341597796 476222826087 215786123488
Opioid 208009807928 283004552352 271305063812
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Heroin 136 674 701 1251 1486 -1209
Opioid 77 -785 853 1212 1442 -868
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Heroin 1452 1472 1571 1681 1891 2173 191
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Heroin 1452 1472 1571 1681 1891 2173 191
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Opioid 77 -785 853 1212 1442 -868
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Heroin 136 674 701 1251 1486 -1209
Q12016-Q12017 Q12016-Q12017 Q12016-Q12017
Q22016-Q22017 Q22016-Q22017 Q22016-Q22017
Q32016-Q32017 Q32016-Q32017 Q32016-Q32017
Page 28: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency Department Data

Two sources- Near real-time syndromic data (visit information within 24-48 hours)- Lagged hospital billing or claims data (usually within 3-4 weeks)

Different variables used- Discharge diagnosis codes (eg ICD-10-CM) ndash available in billing

data and sometimes in syndromic- Free text fields (eg chief complaint provided by Doctor) ndash

available only in syndromic

Rx Summit wwwNationalRxDrugAbuseSummitorg

Case definitions for suspected overdose

If syndromic- Uses both discharge codes (ie ICD-9-CM ICD-10-CM and

SNOMED) and free text fields such as chief complaint or triage notes

- Free text searches use common terms slang and misspellings (eg herion instead of heroin)

If hospital billing or claimshellip- Uses only discharge codes (ie ICD-9-CM ICD-10-CM and

SNOMED)

Discharge codes use are for acute unintentional or undetermined drug poisoning (eg T401X1A in ICD-10-CM) and may also include some substance useabuse codes (ie F11 in ICD-10-CM)

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency medical services data

Capture potential EMS transports to EDs- Excludes instances where individual is pronounced deceased on

the scene inter-facility transports and when EMTs provide no ldquotreatmentrdquo (eg patient refused or required no treatment or transport)

Different variables used- Chief Complaint Secondary complaint- Narrative- Provider Impression- ICD-1O-CM codes- Medication administered (ie Naloxone)- Response to medication administered (ie awake following

Naloxone administration)

Rx Summit wwwNationalRxDrugAbuseSummitorg

Challenges in EMS data

Transition to newer versions of NEMSIS- Some states working in up to three versions (v221 v334 amp

v340)

Different case definitions in different versions

Missing data feeds

Not all EMS agencies share data

Varying time frame in when data is received- lt24 hours to 6 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Data submission process

Rx Summit wwwNationalRxDrugAbuseSummitorg

Sample quality control report

ObsSTATE YEAR QUARTER ERROR_TEXTTOTAL ED VISITS (GENDER)

TOTAL ED VISITS (AGE)

1XX 2017 1 ED Visits mismatch 98287 98309

2XX 2017 2 ED Visits mismatch 98195 98230

3XX 2017 3 ED Visits mismatch 99167 99205

Rx Summit wwwNationalRxDrugAbuseSummitorg

Sample site report

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results All drug (11 sites)

0

10

20

30

40

50

60

70

80

90

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d al

l dru

g ov

erdo

se ra

tes

by

100

00 E

D v

isits

Quarter year

-2000

-1000

000

1000

2000

3000

4000

5000

6000

7000

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Opioid (11 sites)

0

5

10

15

20

25

30

35

40

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Heroin (11 sites)

0

5

10

15

20

25

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-15

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

Annual percentage changes (11 sites)

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Chart1

All drug
Heroin
Opioid
889150252325
302341597796
208009807928
1075831326045
476222826087
283004552352
167997701832
215786123488
271305063812

table with overall

table with overall

All drug
Suspected all drug overdose rates by 10000 ED visits

Sheet1

All drug

table by sex

Opioid
Quarter year
Suspected opioid overdose rates by 10000 ED visits

table by age

Opioid

table by state

Heroin
Quarter year
Suspected opioid overdose rates by 10000 ED visits
Heroin
All drug
Heroin
Opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Summary

Stable increases for all drug and heroin from Q1 2016 to Q3 2017- Opioid had stable increases from Q3 2016 to Q2 2017

Moderate decreases from Q2 to Q3 2017- 9 for all drug 9 for opioid and 12 for heroin

Annual percentage changes were above 15 increases- Q1 to Q1 89 all drug 30 heroin amp 21 opioid- Q2 to Q2 108 all drug 48 heroin amp 28 opioid- Q3 to Q3 17 all drug 22 heroin amp 27 opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency department data dissemination efforts

ldquoOpioid Overdoses Treated in Emergency Departmentsrdquo -httpswwwcdcgovvitalsignsopioid-overdosesindexhtml

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose

Reporting System

Presenter Julie OrsquoDonnell PhD MPHEpidemiologist

Centers for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Alana Vivolo-Kantor R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Julie OrsquoDonnell PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Increase in deaths outpaces increase in use

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid

overdose

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid overdose surveillance

Track specific substances contributing to overdose deaths

Detect newly-emerging substances involved in overdose

Determine risk factors circumstances associated with fatal overdose

Assess common drug combinations Provide more timely data on overdose deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

State Unintentional Drug Overdose Reporting System (SUDORS)

Death certificates

Medical examiner

coroner reportsToxicology

reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data submitted bi-annually

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

1 Data entry started

2 Data entry finished

1 Data entry started

2 Data entry finished

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS leverages National Violent Death Reporting System (NVDRS) platform

- Basic descriptors- Compare across demographics

- Recent release from institution- Overdose location - Survival time

- Mental health diagnoses- Substance abuse treatment history

- Substances present- Substances contributing to death

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Maine 1941 -1273 225 278 1523 -201 3951 -692 257 -813 2945 981 793 656 -299 -2255 3199 2197
Massachusetts na na na na na na 1561 -157 -848 -1148 311 1897 553 -31 -13 -1632 456 2146
New Hampshire 511 1514 -1438 -832 2583 -961 318 64 -433 -1791 2967 -876 825 -184 -1002 -2016 3363 -17
Pennsylvania na na 869 -102 1211 -116 na na 2979 1751 2589 -594 na na 2601 1534 2735 -735
Rhode Island na na 735 -790 1002 -1594 na na 28 454 544 -1191 na na 121 1057 566 -3262
West Virginia -1596 875 2978 -1543 409 -1651 -367 995 4331 -1664 402 -2377 -769 1847 4571 -1584 -199 -3022
Kentucky -102 1242 -1707 2211 1092 -1468 1095 5192 -2694 4045 352 -2002 -043 5541 -3206 5012 -408 -1624
New Mexico 2932 283 521 -078 445 -716 255 -1298 2611 151 -501 -1093 -487 -3061 3227 987 -1715 323
Missouri 068 -304 754 028 114 421 292 827 477 -177 954 767 -046 1839 096 -512 966 125
Ohio na na 107 1216 1596 -1865 na na 2274 2567 2167 -3194 na na 2182 2254 2086 -3348
Wisconsin -229 1388 861 2928 888 931 -948 986 1712 6728 322 314 -1457 91 983 9621 196 668
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 1514 2112 1966 2017 1853 2398 2634
Massachusetts 7036 8133 8006 7327 6486 6687 7956
New Hampshire 3806 3927 4179 3998 3282 4255 3882
Pennsylvania na na 1265 1641 1929 2428 2284
Rhode Island na na 1498 154 161 1698 1496
West Virginia 2258 2176 2392 3428 2857 2972 2266
Kentucky 2095 2325 3532 258 3624 3752 3001
New Mexico 1927 1976 1719 2168 2201 2091 1862
Missouri 1472 1515 1641 1719 1688 185 1991
Ohio na na 236 2897 3641 443 3015
Wisconsin 664 601 66 773 1294 1336 1377
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 502 9 959 931 721 952 1161
Massachusetts 4035 4258 4126 359 3004 3141 3815
New Hampshire 2514 2721 2671 2403 1919 2564 2128
Pennsylvania na na 1013 1277 1473 1876 1738
Rhode Island na na 803 812 898 949 639
West Virginia 1496 1381 1636 2384 2006 1966 1372
Kentucky 1772 1764 2741 1863 2796 2682 2247
New Mexico 902 858 595 787 865 717 74
Missouri 1002 997 118 1192 1131 124 1255
Ohio na na 1804 2198 2693 3254 2165
Wisconsin 286 244 267 293 575 586 625
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 5609 6697 5845 5976 6142 7078 6936
Massachusetts na na na na na na na
New Hampshire 5678 5968 6872 5883 5394 6787 6135
Pennsylvania na na 8374 9102 9010 10100 9983
Rhode Island na na 3567 3829 3527 3880 3262
West Virginia 4628 3889 4229 5489 4642 4832 4034
Kentucky 6756 6687 7517 6234 7613 8444 7205
New Mexico 5291 6842 7036 7402 7345 7672 7123
Missouri 3213 3235 3137 3373 3383 3421 3565
Ohio na na 8696 8789 9859 11432 9300
Wisconsin 2724 2661 3031 3291 4255 4633 5064
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
15 to 24
25 to 34
35 to 54
55 and up
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Male -140 7355 827 901 1286 -927 742 -758 1157 1241 1306 -829 146 301 1082 1242 1306 -1249
Female 841 5151 103 733 1257 -1521 659 -922 533 1204 1494 -1014 -132 1299 229 1331 1617 -1214
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 4888 4820 8365 9057 9873 11142 10110
Female 3201 3470 5257 5312 5701 6418 5442
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 3611 3879 3585 40 4496 5083 4662
Female 159 1695 1538 162 1816 2087 1875
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 2295 2328 2399 2658 2988 3379 2957
Female 839 828 936 957 1085 126 1107
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017 q1 q2 q3
All drug 3948 4061 6589 6894 7458 8430 7696 889150252325 1075831326045 167997701832
Heroin 1452 1472 1571 1681 1891 2173 191 302341597796 476222826087 215786123488
Opioid 2447 2636 2429 2636 2956 3382 3088 208009807928 283004552352 271305063812
Q12016-Q12017 Q22016-Q22017 Q32016-Q32017
All drug 889150252325 1075831326045 167997701832
Heroin 302341597796 476222826087 215786123488
Opioid 208009807928 283004552352 271305063812
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Heroin 136 674 701 1251 1486 -1209
Opioid 77 -785 853 1212 1442 -868
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Heroin 1452 1472 1571 1681 1891 2173 191
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Heroin 1452 1472 1571 1681 1891 2173 191
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Opioid 77 -785 853 1212 1442 -868
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Heroin 136 674 701 1251 1486 -1209
Q12016-Q12017 Q12016-Q12017 Q12016-Q12017
Q22016-Q22017 Q22016-Q22017 Q22016-Q22017
Q32016-Q32017 Q32016-Q32017 Q32016-Q32017
Page 29: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

Case definitions for suspected overdose

If syndromic- Uses both discharge codes (ie ICD-9-CM ICD-10-CM and

SNOMED) and free text fields such as chief complaint or triage notes

- Free text searches use common terms slang and misspellings (eg herion instead of heroin)

If hospital billing or claimshellip- Uses only discharge codes (ie ICD-9-CM ICD-10-CM and

SNOMED)

Discharge codes use are for acute unintentional or undetermined drug poisoning (eg T401X1A in ICD-10-CM) and may also include some substance useabuse codes (ie F11 in ICD-10-CM)

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency medical services data

Capture potential EMS transports to EDs- Excludes instances where individual is pronounced deceased on

the scene inter-facility transports and when EMTs provide no ldquotreatmentrdquo (eg patient refused or required no treatment or transport)

Different variables used- Chief Complaint Secondary complaint- Narrative- Provider Impression- ICD-1O-CM codes- Medication administered (ie Naloxone)- Response to medication administered (ie awake following

Naloxone administration)

Rx Summit wwwNationalRxDrugAbuseSummitorg

Challenges in EMS data

Transition to newer versions of NEMSIS- Some states working in up to three versions (v221 v334 amp

v340)

Different case definitions in different versions

Missing data feeds

Not all EMS agencies share data

Varying time frame in when data is received- lt24 hours to 6 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Data submission process

Rx Summit wwwNationalRxDrugAbuseSummitorg

Sample quality control report

ObsSTATE YEAR QUARTER ERROR_TEXTTOTAL ED VISITS (GENDER)

TOTAL ED VISITS (AGE)

1XX 2017 1 ED Visits mismatch 98287 98309

2XX 2017 2 ED Visits mismatch 98195 98230

3XX 2017 3 ED Visits mismatch 99167 99205

Rx Summit wwwNationalRxDrugAbuseSummitorg

Sample site report

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results All drug (11 sites)

0

10

20

30

40

50

60

70

80

90

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d al

l dru

g ov

erdo

se ra

tes

by

100

00 E

D v

isits

Quarter year

-2000

-1000

000

1000

2000

3000

4000

5000

6000

7000

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Opioid (11 sites)

0

5

10

15

20

25

30

35

40

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Heroin (11 sites)

0

5

10

15

20

25

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-15

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

Annual percentage changes (11 sites)

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Chart1

All drug
Heroin
Opioid
889150252325
302341597796
208009807928
1075831326045
476222826087
283004552352
167997701832
215786123488
271305063812

table with overall

table with overall

All drug
Suspected all drug overdose rates by 10000 ED visits

Sheet1

All drug

table by sex

Opioid
Quarter year
Suspected opioid overdose rates by 10000 ED visits

table by age

Opioid

table by state

Heroin
Quarter year
Suspected opioid overdose rates by 10000 ED visits
Heroin
All drug
Heroin
Opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Summary

Stable increases for all drug and heroin from Q1 2016 to Q3 2017- Opioid had stable increases from Q3 2016 to Q2 2017

Moderate decreases from Q2 to Q3 2017- 9 for all drug 9 for opioid and 12 for heroin

Annual percentage changes were above 15 increases- Q1 to Q1 89 all drug 30 heroin amp 21 opioid- Q2 to Q2 108 all drug 48 heroin amp 28 opioid- Q3 to Q3 17 all drug 22 heroin amp 27 opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency department data dissemination efforts

ldquoOpioid Overdoses Treated in Emergency Departmentsrdquo -httpswwwcdcgovvitalsignsopioid-overdosesindexhtml

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose

Reporting System

Presenter Julie OrsquoDonnell PhD MPHEpidemiologist

Centers for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Alana Vivolo-Kantor R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Julie OrsquoDonnell PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Increase in deaths outpaces increase in use

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid

overdose

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid overdose surveillance

Track specific substances contributing to overdose deaths

Detect newly-emerging substances involved in overdose

Determine risk factors circumstances associated with fatal overdose

Assess common drug combinations Provide more timely data on overdose deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

State Unintentional Drug Overdose Reporting System (SUDORS)

Death certificates

Medical examiner

coroner reportsToxicology

reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data submitted bi-annually

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

1 Data entry started

2 Data entry finished

1 Data entry started

2 Data entry finished

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS leverages National Violent Death Reporting System (NVDRS) platform

- Basic descriptors- Compare across demographics

- Recent release from institution- Overdose location - Survival time

- Mental health diagnoses- Substance abuse treatment history

- Substances present- Substances contributing to death

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Maine 1941 -1273 225 278 1523 -201 3951 -692 257 -813 2945 981 793 656 -299 -2255 3199 2197
Massachusetts na na na na na na 1561 -157 -848 -1148 311 1897 553 -31 -13 -1632 456 2146
New Hampshire 511 1514 -1438 -832 2583 -961 318 64 -433 -1791 2967 -876 825 -184 -1002 -2016 3363 -17
Pennsylvania na na 869 -102 1211 -116 na na 2979 1751 2589 -594 na na 2601 1534 2735 -735
Rhode Island na na 735 -790 1002 -1594 na na 28 454 544 -1191 na na 121 1057 566 -3262
West Virginia -1596 875 2978 -1543 409 -1651 -367 995 4331 -1664 402 -2377 -769 1847 4571 -1584 -199 -3022
Kentucky -102 1242 -1707 2211 1092 -1468 1095 5192 -2694 4045 352 -2002 -043 5541 -3206 5012 -408 -1624
New Mexico 2932 283 521 -078 445 -716 255 -1298 2611 151 -501 -1093 -487 -3061 3227 987 -1715 323
Missouri 068 -304 754 028 114 421 292 827 477 -177 954 767 -046 1839 096 -512 966 125
Ohio na na 107 1216 1596 -1865 na na 2274 2567 2167 -3194 na na 2182 2254 2086 -3348
Wisconsin -229 1388 861 2928 888 931 -948 986 1712 6728 322 314 -1457 91 983 9621 196 668
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 1514 2112 1966 2017 1853 2398 2634
Massachusetts 7036 8133 8006 7327 6486 6687 7956
New Hampshire 3806 3927 4179 3998 3282 4255 3882
Pennsylvania na na 1265 1641 1929 2428 2284
Rhode Island na na 1498 154 161 1698 1496
West Virginia 2258 2176 2392 3428 2857 2972 2266
Kentucky 2095 2325 3532 258 3624 3752 3001
New Mexico 1927 1976 1719 2168 2201 2091 1862
Missouri 1472 1515 1641 1719 1688 185 1991
Ohio na na 236 2897 3641 443 3015
Wisconsin 664 601 66 773 1294 1336 1377
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 502 9 959 931 721 952 1161
Massachusetts 4035 4258 4126 359 3004 3141 3815
New Hampshire 2514 2721 2671 2403 1919 2564 2128
Pennsylvania na na 1013 1277 1473 1876 1738
Rhode Island na na 803 812 898 949 639
West Virginia 1496 1381 1636 2384 2006 1966 1372
Kentucky 1772 1764 2741 1863 2796 2682 2247
New Mexico 902 858 595 787 865 717 74
Missouri 1002 997 118 1192 1131 124 1255
Ohio na na 1804 2198 2693 3254 2165
Wisconsin 286 244 267 293 575 586 625
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 5609 6697 5845 5976 6142 7078 6936
Massachusetts na na na na na na na
New Hampshire 5678 5968 6872 5883 5394 6787 6135
Pennsylvania na na 8374 9102 9010 10100 9983
Rhode Island na na 3567 3829 3527 3880 3262
West Virginia 4628 3889 4229 5489 4642 4832 4034
Kentucky 6756 6687 7517 6234 7613 8444 7205
New Mexico 5291 6842 7036 7402 7345 7672 7123
Missouri 3213 3235 3137 3373 3383 3421 3565
Ohio na na 8696 8789 9859 11432 9300
Wisconsin 2724 2661 3031 3291 4255 4633 5064
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
15 to 24
25 to 34
35 to 54
55 and up
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Male -140 7355 827 901 1286 -927 742 -758 1157 1241 1306 -829 146 301 1082 1242 1306 -1249
Female 841 5151 103 733 1257 -1521 659 -922 533 1204 1494 -1014 -132 1299 229 1331 1617 -1214
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 4888 4820 8365 9057 9873 11142 10110
Female 3201 3470 5257 5312 5701 6418 5442
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 3611 3879 3585 40 4496 5083 4662
Female 159 1695 1538 162 1816 2087 1875
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 2295 2328 2399 2658 2988 3379 2957
Female 839 828 936 957 1085 126 1107
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017 q1 q2 q3
All drug 3948 4061 6589 6894 7458 8430 7696 889150252325 1075831326045 167997701832
Heroin 1452 1472 1571 1681 1891 2173 191 302341597796 476222826087 215786123488
Opioid 2447 2636 2429 2636 2956 3382 3088 208009807928 283004552352 271305063812
Q12016-Q12017 Q22016-Q22017 Q32016-Q32017
All drug 889150252325 1075831326045 167997701832
Heroin 302341597796 476222826087 215786123488
Opioid 208009807928 283004552352 271305063812
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Heroin 136 674 701 1251 1486 -1209
Opioid 77 -785 853 1212 1442 -868
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Heroin 1452 1472 1571 1681 1891 2173 191
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Heroin 1452 1472 1571 1681 1891 2173 191
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Opioid 77 -785 853 1212 1442 -868
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Heroin 136 674 701 1251 1486 -1209
Q12016-Q12017 Q12016-Q12017 Q12016-Q12017
Q22016-Q22017 Q22016-Q22017 Q22016-Q22017
Q32016-Q32017 Q32016-Q32017 Q32016-Q32017
Page 30: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency medical services data

Capture potential EMS transports to EDs- Excludes instances where individual is pronounced deceased on

the scene inter-facility transports and when EMTs provide no ldquotreatmentrdquo (eg patient refused or required no treatment or transport)

Different variables used- Chief Complaint Secondary complaint- Narrative- Provider Impression- ICD-1O-CM codes- Medication administered (ie Naloxone)- Response to medication administered (ie awake following

Naloxone administration)

Rx Summit wwwNationalRxDrugAbuseSummitorg

Challenges in EMS data

Transition to newer versions of NEMSIS- Some states working in up to three versions (v221 v334 amp

v340)

Different case definitions in different versions

Missing data feeds

Not all EMS agencies share data

Varying time frame in when data is received- lt24 hours to 6 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Data submission process

Rx Summit wwwNationalRxDrugAbuseSummitorg

Sample quality control report

ObsSTATE YEAR QUARTER ERROR_TEXTTOTAL ED VISITS (GENDER)

TOTAL ED VISITS (AGE)

1XX 2017 1 ED Visits mismatch 98287 98309

2XX 2017 2 ED Visits mismatch 98195 98230

3XX 2017 3 ED Visits mismatch 99167 99205

Rx Summit wwwNationalRxDrugAbuseSummitorg

Sample site report

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results All drug (11 sites)

0

10

20

30

40

50

60

70

80

90

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d al

l dru

g ov

erdo

se ra

tes

by

100

00 E

D v

isits

Quarter year

-2000

-1000

000

1000

2000

3000

4000

5000

6000

7000

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Opioid (11 sites)

0

5

10

15

20

25

30

35

40

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Heroin (11 sites)

0

5

10

15

20

25

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-15

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

Annual percentage changes (11 sites)

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Chart1

All drug
Heroin
Opioid
889150252325
302341597796
208009807928
1075831326045
476222826087
283004552352
167997701832
215786123488
271305063812

table with overall

table with overall

All drug
Suspected all drug overdose rates by 10000 ED visits

Sheet1

All drug

table by sex

Opioid
Quarter year
Suspected opioid overdose rates by 10000 ED visits

table by age

Opioid

table by state

Heroin
Quarter year
Suspected opioid overdose rates by 10000 ED visits
Heroin
All drug
Heroin
Opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Summary

Stable increases for all drug and heroin from Q1 2016 to Q3 2017- Opioid had stable increases from Q3 2016 to Q2 2017

Moderate decreases from Q2 to Q3 2017- 9 for all drug 9 for opioid and 12 for heroin

Annual percentage changes were above 15 increases- Q1 to Q1 89 all drug 30 heroin amp 21 opioid- Q2 to Q2 108 all drug 48 heroin amp 28 opioid- Q3 to Q3 17 all drug 22 heroin amp 27 opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency department data dissemination efforts

ldquoOpioid Overdoses Treated in Emergency Departmentsrdquo -httpswwwcdcgovvitalsignsopioid-overdosesindexhtml

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose

Reporting System

Presenter Julie OrsquoDonnell PhD MPHEpidemiologist

Centers for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Alana Vivolo-Kantor R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Julie OrsquoDonnell PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Increase in deaths outpaces increase in use

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid

overdose

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid overdose surveillance

Track specific substances contributing to overdose deaths

Detect newly-emerging substances involved in overdose

Determine risk factors circumstances associated with fatal overdose

Assess common drug combinations Provide more timely data on overdose deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

State Unintentional Drug Overdose Reporting System (SUDORS)

Death certificates

Medical examiner

coroner reportsToxicology

reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data submitted bi-annually

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

1 Data entry started

2 Data entry finished

1 Data entry started

2 Data entry finished

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS leverages National Violent Death Reporting System (NVDRS) platform

- Basic descriptors- Compare across demographics

- Recent release from institution- Overdose location - Survival time

- Mental health diagnoses- Substance abuse treatment history

- Substances present- Substances contributing to death

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Maine 1941 -1273 225 278 1523 -201 3951 -692 257 -813 2945 981 793 656 -299 -2255 3199 2197
Massachusetts na na na na na na 1561 -157 -848 -1148 311 1897 553 -31 -13 -1632 456 2146
New Hampshire 511 1514 -1438 -832 2583 -961 318 64 -433 -1791 2967 -876 825 -184 -1002 -2016 3363 -17
Pennsylvania na na 869 -102 1211 -116 na na 2979 1751 2589 -594 na na 2601 1534 2735 -735
Rhode Island na na 735 -790 1002 -1594 na na 28 454 544 -1191 na na 121 1057 566 -3262
West Virginia -1596 875 2978 -1543 409 -1651 -367 995 4331 -1664 402 -2377 -769 1847 4571 -1584 -199 -3022
Kentucky -102 1242 -1707 2211 1092 -1468 1095 5192 -2694 4045 352 -2002 -043 5541 -3206 5012 -408 -1624
New Mexico 2932 283 521 -078 445 -716 255 -1298 2611 151 -501 -1093 -487 -3061 3227 987 -1715 323
Missouri 068 -304 754 028 114 421 292 827 477 -177 954 767 -046 1839 096 -512 966 125
Ohio na na 107 1216 1596 -1865 na na 2274 2567 2167 -3194 na na 2182 2254 2086 -3348
Wisconsin -229 1388 861 2928 888 931 -948 986 1712 6728 322 314 -1457 91 983 9621 196 668
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 1514 2112 1966 2017 1853 2398 2634
Massachusetts 7036 8133 8006 7327 6486 6687 7956
New Hampshire 3806 3927 4179 3998 3282 4255 3882
Pennsylvania na na 1265 1641 1929 2428 2284
Rhode Island na na 1498 154 161 1698 1496
West Virginia 2258 2176 2392 3428 2857 2972 2266
Kentucky 2095 2325 3532 258 3624 3752 3001
New Mexico 1927 1976 1719 2168 2201 2091 1862
Missouri 1472 1515 1641 1719 1688 185 1991
Ohio na na 236 2897 3641 443 3015
Wisconsin 664 601 66 773 1294 1336 1377
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 502 9 959 931 721 952 1161
Massachusetts 4035 4258 4126 359 3004 3141 3815
New Hampshire 2514 2721 2671 2403 1919 2564 2128
Pennsylvania na na 1013 1277 1473 1876 1738
Rhode Island na na 803 812 898 949 639
West Virginia 1496 1381 1636 2384 2006 1966 1372
Kentucky 1772 1764 2741 1863 2796 2682 2247
New Mexico 902 858 595 787 865 717 74
Missouri 1002 997 118 1192 1131 124 1255
Ohio na na 1804 2198 2693 3254 2165
Wisconsin 286 244 267 293 575 586 625
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 5609 6697 5845 5976 6142 7078 6936
Massachusetts na na na na na na na
New Hampshire 5678 5968 6872 5883 5394 6787 6135
Pennsylvania na na 8374 9102 9010 10100 9983
Rhode Island na na 3567 3829 3527 3880 3262
West Virginia 4628 3889 4229 5489 4642 4832 4034
Kentucky 6756 6687 7517 6234 7613 8444 7205
New Mexico 5291 6842 7036 7402 7345 7672 7123
Missouri 3213 3235 3137 3373 3383 3421 3565
Ohio na na 8696 8789 9859 11432 9300
Wisconsin 2724 2661 3031 3291 4255 4633 5064
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
15 to 24
25 to 34
35 to 54
55 and up
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Male -140 7355 827 901 1286 -927 742 -758 1157 1241 1306 -829 146 301 1082 1242 1306 -1249
Female 841 5151 103 733 1257 -1521 659 -922 533 1204 1494 -1014 -132 1299 229 1331 1617 -1214
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 4888 4820 8365 9057 9873 11142 10110
Female 3201 3470 5257 5312 5701 6418 5442
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 3611 3879 3585 40 4496 5083 4662
Female 159 1695 1538 162 1816 2087 1875
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 2295 2328 2399 2658 2988 3379 2957
Female 839 828 936 957 1085 126 1107
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017 q1 q2 q3
All drug 3948 4061 6589 6894 7458 8430 7696 889150252325 1075831326045 167997701832
Heroin 1452 1472 1571 1681 1891 2173 191 302341597796 476222826087 215786123488
Opioid 2447 2636 2429 2636 2956 3382 3088 208009807928 283004552352 271305063812
Q12016-Q12017 Q22016-Q22017 Q32016-Q32017
All drug 889150252325 1075831326045 167997701832
Heroin 302341597796 476222826087 215786123488
Opioid 208009807928 283004552352 271305063812
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Heroin 136 674 701 1251 1486 -1209
Opioid 77 -785 853 1212 1442 -868
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Heroin 1452 1472 1571 1681 1891 2173 191
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Heroin 1452 1472 1571 1681 1891 2173 191
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Opioid 77 -785 853 1212 1442 -868
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Heroin 136 674 701 1251 1486 -1209
Q12016-Q12017 Q12016-Q12017 Q12016-Q12017
Q22016-Q22017 Q22016-Q22017 Q22016-Q22017
Q32016-Q32017 Q32016-Q32017 Q32016-Q32017
Page 31: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

Challenges in EMS data

Transition to newer versions of NEMSIS- Some states working in up to three versions (v221 v334 amp

v340)

Different case definitions in different versions

Missing data feeds

Not all EMS agencies share data

Varying time frame in when data is received- lt24 hours to 6 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Data submission process

Rx Summit wwwNationalRxDrugAbuseSummitorg

Sample quality control report

ObsSTATE YEAR QUARTER ERROR_TEXTTOTAL ED VISITS (GENDER)

TOTAL ED VISITS (AGE)

1XX 2017 1 ED Visits mismatch 98287 98309

2XX 2017 2 ED Visits mismatch 98195 98230

3XX 2017 3 ED Visits mismatch 99167 99205

Rx Summit wwwNationalRxDrugAbuseSummitorg

Sample site report

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results All drug (11 sites)

0

10

20

30

40

50

60

70

80

90

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d al

l dru

g ov

erdo

se ra

tes

by

100

00 E

D v

isits

Quarter year

-2000

-1000

000

1000

2000

3000

4000

5000

6000

7000

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Opioid (11 sites)

0

5

10

15

20

25

30

35

40

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Heroin (11 sites)

0

5

10

15

20

25

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-15

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

Annual percentage changes (11 sites)

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Chart1

All drug
Heroin
Opioid
889150252325
302341597796
208009807928
1075831326045
476222826087
283004552352
167997701832
215786123488
271305063812

table with overall

table with overall

All drug
Suspected all drug overdose rates by 10000 ED visits

Sheet1

All drug

table by sex

Opioid
Quarter year
Suspected opioid overdose rates by 10000 ED visits

table by age

Opioid

table by state

Heroin
Quarter year
Suspected opioid overdose rates by 10000 ED visits
Heroin
All drug
Heroin
Opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Summary

Stable increases for all drug and heroin from Q1 2016 to Q3 2017- Opioid had stable increases from Q3 2016 to Q2 2017

Moderate decreases from Q2 to Q3 2017- 9 for all drug 9 for opioid and 12 for heroin

Annual percentage changes were above 15 increases- Q1 to Q1 89 all drug 30 heroin amp 21 opioid- Q2 to Q2 108 all drug 48 heroin amp 28 opioid- Q3 to Q3 17 all drug 22 heroin amp 27 opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency department data dissemination efforts

ldquoOpioid Overdoses Treated in Emergency Departmentsrdquo -httpswwwcdcgovvitalsignsopioid-overdosesindexhtml

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose

Reporting System

Presenter Julie OrsquoDonnell PhD MPHEpidemiologist

Centers for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Alana Vivolo-Kantor R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Julie OrsquoDonnell PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Increase in deaths outpaces increase in use

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid

overdose

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid overdose surveillance

Track specific substances contributing to overdose deaths

Detect newly-emerging substances involved in overdose

Determine risk factors circumstances associated with fatal overdose

Assess common drug combinations Provide more timely data on overdose deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

State Unintentional Drug Overdose Reporting System (SUDORS)

Death certificates

Medical examiner

coroner reportsToxicology

reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data submitted bi-annually

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

1 Data entry started

2 Data entry finished

1 Data entry started

2 Data entry finished

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS leverages National Violent Death Reporting System (NVDRS) platform

- Basic descriptors- Compare across demographics

- Recent release from institution- Overdose location - Survival time

- Mental health diagnoses- Substance abuse treatment history

- Substances present- Substances contributing to death

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Maine 1941 -1273 225 278 1523 -201 3951 -692 257 -813 2945 981 793 656 -299 -2255 3199 2197
Massachusetts na na na na na na 1561 -157 -848 -1148 311 1897 553 -31 -13 -1632 456 2146
New Hampshire 511 1514 -1438 -832 2583 -961 318 64 -433 -1791 2967 -876 825 -184 -1002 -2016 3363 -17
Pennsylvania na na 869 -102 1211 -116 na na 2979 1751 2589 -594 na na 2601 1534 2735 -735
Rhode Island na na 735 -790 1002 -1594 na na 28 454 544 -1191 na na 121 1057 566 -3262
West Virginia -1596 875 2978 -1543 409 -1651 -367 995 4331 -1664 402 -2377 -769 1847 4571 -1584 -199 -3022
Kentucky -102 1242 -1707 2211 1092 -1468 1095 5192 -2694 4045 352 -2002 -043 5541 -3206 5012 -408 -1624
New Mexico 2932 283 521 -078 445 -716 255 -1298 2611 151 -501 -1093 -487 -3061 3227 987 -1715 323
Missouri 068 -304 754 028 114 421 292 827 477 -177 954 767 -046 1839 096 -512 966 125
Ohio na na 107 1216 1596 -1865 na na 2274 2567 2167 -3194 na na 2182 2254 2086 -3348
Wisconsin -229 1388 861 2928 888 931 -948 986 1712 6728 322 314 -1457 91 983 9621 196 668
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 1514 2112 1966 2017 1853 2398 2634
Massachusetts 7036 8133 8006 7327 6486 6687 7956
New Hampshire 3806 3927 4179 3998 3282 4255 3882
Pennsylvania na na 1265 1641 1929 2428 2284
Rhode Island na na 1498 154 161 1698 1496
West Virginia 2258 2176 2392 3428 2857 2972 2266
Kentucky 2095 2325 3532 258 3624 3752 3001
New Mexico 1927 1976 1719 2168 2201 2091 1862
Missouri 1472 1515 1641 1719 1688 185 1991
Ohio na na 236 2897 3641 443 3015
Wisconsin 664 601 66 773 1294 1336 1377
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 502 9 959 931 721 952 1161
Massachusetts 4035 4258 4126 359 3004 3141 3815
New Hampshire 2514 2721 2671 2403 1919 2564 2128
Pennsylvania na na 1013 1277 1473 1876 1738
Rhode Island na na 803 812 898 949 639
West Virginia 1496 1381 1636 2384 2006 1966 1372
Kentucky 1772 1764 2741 1863 2796 2682 2247
New Mexico 902 858 595 787 865 717 74
Missouri 1002 997 118 1192 1131 124 1255
Ohio na na 1804 2198 2693 3254 2165
Wisconsin 286 244 267 293 575 586 625
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 5609 6697 5845 5976 6142 7078 6936
Massachusetts na na na na na na na
New Hampshire 5678 5968 6872 5883 5394 6787 6135
Pennsylvania na na 8374 9102 9010 10100 9983
Rhode Island na na 3567 3829 3527 3880 3262
West Virginia 4628 3889 4229 5489 4642 4832 4034
Kentucky 6756 6687 7517 6234 7613 8444 7205
New Mexico 5291 6842 7036 7402 7345 7672 7123
Missouri 3213 3235 3137 3373 3383 3421 3565
Ohio na na 8696 8789 9859 11432 9300
Wisconsin 2724 2661 3031 3291 4255 4633 5064
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
15 to 24
25 to 34
35 to 54
55 and up
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Male -140 7355 827 901 1286 -927 742 -758 1157 1241 1306 -829 146 301 1082 1242 1306 -1249
Female 841 5151 103 733 1257 -1521 659 -922 533 1204 1494 -1014 -132 1299 229 1331 1617 -1214
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 4888 4820 8365 9057 9873 11142 10110
Female 3201 3470 5257 5312 5701 6418 5442
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 3611 3879 3585 40 4496 5083 4662
Female 159 1695 1538 162 1816 2087 1875
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 2295 2328 2399 2658 2988 3379 2957
Female 839 828 936 957 1085 126 1107
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017 q1 q2 q3
All drug 3948 4061 6589 6894 7458 8430 7696 889150252325 1075831326045 167997701832
Heroin 1452 1472 1571 1681 1891 2173 191 302341597796 476222826087 215786123488
Opioid 2447 2636 2429 2636 2956 3382 3088 208009807928 283004552352 271305063812
Q12016-Q12017 Q22016-Q22017 Q32016-Q32017
All drug 889150252325 1075831326045 167997701832
Heroin 302341597796 476222826087 215786123488
Opioid 208009807928 283004552352 271305063812
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Heroin 136 674 701 1251 1486 -1209
Opioid 77 -785 853 1212 1442 -868
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Heroin 1452 1472 1571 1681 1891 2173 191
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Heroin 1452 1472 1571 1681 1891 2173 191
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Opioid 77 -785 853 1212 1442 -868
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Heroin 136 674 701 1251 1486 -1209
Q12016-Q12017 Q12016-Q12017 Q12016-Q12017
Q22016-Q22017 Q22016-Q22017 Q22016-Q22017
Q32016-Q32017 Q32016-Q32017 Q32016-Q32017
Page 32: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

Data submission process

Rx Summit wwwNationalRxDrugAbuseSummitorg

Sample quality control report

ObsSTATE YEAR QUARTER ERROR_TEXTTOTAL ED VISITS (GENDER)

TOTAL ED VISITS (AGE)

1XX 2017 1 ED Visits mismatch 98287 98309

2XX 2017 2 ED Visits mismatch 98195 98230

3XX 2017 3 ED Visits mismatch 99167 99205

Rx Summit wwwNationalRxDrugAbuseSummitorg

Sample site report

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results All drug (11 sites)

0

10

20

30

40

50

60

70

80

90

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d al

l dru

g ov

erdo

se ra

tes

by

100

00 E

D v

isits

Quarter year

-2000

-1000

000

1000

2000

3000

4000

5000

6000

7000

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Opioid (11 sites)

0

5

10

15

20

25

30

35

40

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Heroin (11 sites)

0

5

10

15

20

25

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-15

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

Annual percentage changes (11 sites)

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Chart1

All drug
Heroin
Opioid
889150252325
302341597796
208009807928
1075831326045
476222826087
283004552352
167997701832
215786123488
271305063812

table with overall

table with overall

All drug
Suspected all drug overdose rates by 10000 ED visits

Sheet1

All drug

table by sex

Opioid
Quarter year
Suspected opioid overdose rates by 10000 ED visits

table by age

Opioid

table by state

Heroin
Quarter year
Suspected opioid overdose rates by 10000 ED visits
Heroin
All drug
Heroin
Opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Summary

Stable increases for all drug and heroin from Q1 2016 to Q3 2017- Opioid had stable increases from Q3 2016 to Q2 2017

Moderate decreases from Q2 to Q3 2017- 9 for all drug 9 for opioid and 12 for heroin

Annual percentage changes were above 15 increases- Q1 to Q1 89 all drug 30 heroin amp 21 opioid- Q2 to Q2 108 all drug 48 heroin amp 28 opioid- Q3 to Q3 17 all drug 22 heroin amp 27 opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency department data dissemination efforts

ldquoOpioid Overdoses Treated in Emergency Departmentsrdquo -httpswwwcdcgovvitalsignsopioid-overdosesindexhtml

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose

Reporting System

Presenter Julie OrsquoDonnell PhD MPHEpidemiologist

Centers for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Alana Vivolo-Kantor R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Julie OrsquoDonnell PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Increase in deaths outpaces increase in use

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid

overdose

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid overdose surveillance

Track specific substances contributing to overdose deaths

Detect newly-emerging substances involved in overdose

Determine risk factors circumstances associated with fatal overdose

Assess common drug combinations Provide more timely data on overdose deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

State Unintentional Drug Overdose Reporting System (SUDORS)

Death certificates

Medical examiner

coroner reportsToxicology

reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data submitted bi-annually

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

1 Data entry started

2 Data entry finished

1 Data entry started

2 Data entry finished

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS leverages National Violent Death Reporting System (NVDRS) platform

- Basic descriptors- Compare across demographics

- Recent release from institution- Overdose location - Survival time

- Mental health diagnoses- Substance abuse treatment history

- Substances present- Substances contributing to death

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Maine 1941 -1273 225 278 1523 -201 3951 -692 257 -813 2945 981 793 656 -299 -2255 3199 2197
Massachusetts na na na na na na 1561 -157 -848 -1148 311 1897 553 -31 -13 -1632 456 2146
New Hampshire 511 1514 -1438 -832 2583 -961 318 64 -433 -1791 2967 -876 825 -184 -1002 -2016 3363 -17
Pennsylvania na na 869 -102 1211 -116 na na 2979 1751 2589 -594 na na 2601 1534 2735 -735
Rhode Island na na 735 -790 1002 -1594 na na 28 454 544 -1191 na na 121 1057 566 -3262
West Virginia -1596 875 2978 -1543 409 -1651 -367 995 4331 -1664 402 -2377 -769 1847 4571 -1584 -199 -3022
Kentucky -102 1242 -1707 2211 1092 -1468 1095 5192 -2694 4045 352 -2002 -043 5541 -3206 5012 -408 -1624
New Mexico 2932 283 521 -078 445 -716 255 -1298 2611 151 -501 -1093 -487 -3061 3227 987 -1715 323
Missouri 068 -304 754 028 114 421 292 827 477 -177 954 767 -046 1839 096 -512 966 125
Ohio na na 107 1216 1596 -1865 na na 2274 2567 2167 -3194 na na 2182 2254 2086 -3348
Wisconsin -229 1388 861 2928 888 931 -948 986 1712 6728 322 314 -1457 91 983 9621 196 668
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 1514 2112 1966 2017 1853 2398 2634
Massachusetts 7036 8133 8006 7327 6486 6687 7956
New Hampshire 3806 3927 4179 3998 3282 4255 3882
Pennsylvania na na 1265 1641 1929 2428 2284
Rhode Island na na 1498 154 161 1698 1496
West Virginia 2258 2176 2392 3428 2857 2972 2266
Kentucky 2095 2325 3532 258 3624 3752 3001
New Mexico 1927 1976 1719 2168 2201 2091 1862
Missouri 1472 1515 1641 1719 1688 185 1991
Ohio na na 236 2897 3641 443 3015
Wisconsin 664 601 66 773 1294 1336 1377
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 502 9 959 931 721 952 1161
Massachusetts 4035 4258 4126 359 3004 3141 3815
New Hampshire 2514 2721 2671 2403 1919 2564 2128
Pennsylvania na na 1013 1277 1473 1876 1738
Rhode Island na na 803 812 898 949 639
West Virginia 1496 1381 1636 2384 2006 1966 1372
Kentucky 1772 1764 2741 1863 2796 2682 2247
New Mexico 902 858 595 787 865 717 74
Missouri 1002 997 118 1192 1131 124 1255
Ohio na na 1804 2198 2693 3254 2165
Wisconsin 286 244 267 293 575 586 625
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 5609 6697 5845 5976 6142 7078 6936
Massachusetts na na na na na na na
New Hampshire 5678 5968 6872 5883 5394 6787 6135
Pennsylvania na na 8374 9102 9010 10100 9983
Rhode Island na na 3567 3829 3527 3880 3262
West Virginia 4628 3889 4229 5489 4642 4832 4034
Kentucky 6756 6687 7517 6234 7613 8444 7205
New Mexico 5291 6842 7036 7402 7345 7672 7123
Missouri 3213 3235 3137 3373 3383 3421 3565
Ohio na na 8696 8789 9859 11432 9300
Wisconsin 2724 2661 3031 3291 4255 4633 5064
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
15 to 24
25 to 34
35 to 54
55 and up
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Male -140 7355 827 901 1286 -927 742 -758 1157 1241 1306 -829 146 301 1082 1242 1306 -1249
Female 841 5151 103 733 1257 -1521 659 -922 533 1204 1494 -1014 -132 1299 229 1331 1617 -1214
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 4888 4820 8365 9057 9873 11142 10110
Female 3201 3470 5257 5312 5701 6418 5442
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 3611 3879 3585 40 4496 5083 4662
Female 159 1695 1538 162 1816 2087 1875
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 2295 2328 2399 2658 2988 3379 2957
Female 839 828 936 957 1085 126 1107
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017 q1 q2 q3
All drug 3948 4061 6589 6894 7458 8430 7696 889150252325 1075831326045 167997701832
Heroin 1452 1472 1571 1681 1891 2173 191 302341597796 476222826087 215786123488
Opioid 2447 2636 2429 2636 2956 3382 3088 208009807928 283004552352 271305063812
Q12016-Q12017 Q22016-Q22017 Q32016-Q32017
All drug 889150252325 1075831326045 167997701832
Heroin 302341597796 476222826087 215786123488
Opioid 208009807928 283004552352 271305063812
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Heroin 136 674 701 1251 1486 -1209
Opioid 77 -785 853 1212 1442 -868
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Heroin 1452 1472 1571 1681 1891 2173 191
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Heroin 1452 1472 1571 1681 1891 2173 191
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Opioid 77 -785 853 1212 1442 -868
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Heroin 136 674 701 1251 1486 -1209
Q12016-Q12017 Q12016-Q12017 Q12016-Q12017
Q22016-Q22017 Q22016-Q22017 Q22016-Q22017
Q32016-Q32017 Q32016-Q32017 Q32016-Q32017
Page 33: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

Sample quality control report

ObsSTATE YEAR QUARTER ERROR_TEXTTOTAL ED VISITS (GENDER)

TOTAL ED VISITS (AGE)

1XX 2017 1 ED Visits mismatch 98287 98309

2XX 2017 2 ED Visits mismatch 98195 98230

3XX 2017 3 ED Visits mismatch 99167 99205

Rx Summit wwwNationalRxDrugAbuseSummitorg

Sample site report

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results All drug (11 sites)

0

10

20

30

40

50

60

70

80

90

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d al

l dru

g ov

erdo

se ra

tes

by

100

00 E

D v

isits

Quarter year

-2000

-1000

000

1000

2000

3000

4000

5000

6000

7000

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Opioid (11 sites)

0

5

10

15

20

25

30

35

40

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Heroin (11 sites)

0

5

10

15

20

25

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-15

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

Annual percentage changes (11 sites)

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Chart1

All drug
Heroin
Opioid
889150252325
302341597796
208009807928
1075831326045
476222826087
283004552352
167997701832
215786123488
271305063812

table with overall

table with overall

All drug
Suspected all drug overdose rates by 10000 ED visits

Sheet1

All drug

table by sex

Opioid
Quarter year
Suspected opioid overdose rates by 10000 ED visits

table by age

Opioid

table by state

Heroin
Quarter year
Suspected opioid overdose rates by 10000 ED visits
Heroin
All drug
Heroin
Opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Summary

Stable increases for all drug and heroin from Q1 2016 to Q3 2017- Opioid had stable increases from Q3 2016 to Q2 2017

Moderate decreases from Q2 to Q3 2017- 9 for all drug 9 for opioid and 12 for heroin

Annual percentage changes were above 15 increases- Q1 to Q1 89 all drug 30 heroin amp 21 opioid- Q2 to Q2 108 all drug 48 heroin amp 28 opioid- Q3 to Q3 17 all drug 22 heroin amp 27 opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency department data dissemination efforts

ldquoOpioid Overdoses Treated in Emergency Departmentsrdquo -httpswwwcdcgovvitalsignsopioid-overdosesindexhtml

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose

Reporting System

Presenter Julie OrsquoDonnell PhD MPHEpidemiologist

Centers for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Alana Vivolo-Kantor R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Julie OrsquoDonnell PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Increase in deaths outpaces increase in use

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid

overdose

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid overdose surveillance

Track specific substances contributing to overdose deaths

Detect newly-emerging substances involved in overdose

Determine risk factors circumstances associated with fatal overdose

Assess common drug combinations Provide more timely data on overdose deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

State Unintentional Drug Overdose Reporting System (SUDORS)

Death certificates

Medical examiner

coroner reportsToxicology

reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data submitted bi-annually

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

1 Data entry started

2 Data entry finished

1 Data entry started

2 Data entry finished

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS leverages National Violent Death Reporting System (NVDRS) platform

- Basic descriptors- Compare across demographics

- Recent release from institution- Overdose location - Survival time

- Mental health diagnoses- Substance abuse treatment history

- Substances present- Substances contributing to death

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Maine 1941 -1273 225 278 1523 -201 3951 -692 257 -813 2945 981 793 656 -299 -2255 3199 2197
Massachusetts na na na na na na 1561 -157 -848 -1148 311 1897 553 -31 -13 -1632 456 2146
New Hampshire 511 1514 -1438 -832 2583 -961 318 64 -433 -1791 2967 -876 825 -184 -1002 -2016 3363 -17
Pennsylvania na na 869 -102 1211 -116 na na 2979 1751 2589 -594 na na 2601 1534 2735 -735
Rhode Island na na 735 -790 1002 -1594 na na 28 454 544 -1191 na na 121 1057 566 -3262
West Virginia -1596 875 2978 -1543 409 -1651 -367 995 4331 -1664 402 -2377 -769 1847 4571 -1584 -199 -3022
Kentucky -102 1242 -1707 2211 1092 -1468 1095 5192 -2694 4045 352 -2002 -043 5541 -3206 5012 -408 -1624
New Mexico 2932 283 521 -078 445 -716 255 -1298 2611 151 -501 -1093 -487 -3061 3227 987 -1715 323
Missouri 068 -304 754 028 114 421 292 827 477 -177 954 767 -046 1839 096 -512 966 125
Ohio na na 107 1216 1596 -1865 na na 2274 2567 2167 -3194 na na 2182 2254 2086 -3348
Wisconsin -229 1388 861 2928 888 931 -948 986 1712 6728 322 314 -1457 91 983 9621 196 668
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 1514 2112 1966 2017 1853 2398 2634
Massachusetts 7036 8133 8006 7327 6486 6687 7956
New Hampshire 3806 3927 4179 3998 3282 4255 3882
Pennsylvania na na 1265 1641 1929 2428 2284
Rhode Island na na 1498 154 161 1698 1496
West Virginia 2258 2176 2392 3428 2857 2972 2266
Kentucky 2095 2325 3532 258 3624 3752 3001
New Mexico 1927 1976 1719 2168 2201 2091 1862
Missouri 1472 1515 1641 1719 1688 185 1991
Ohio na na 236 2897 3641 443 3015
Wisconsin 664 601 66 773 1294 1336 1377
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 502 9 959 931 721 952 1161
Massachusetts 4035 4258 4126 359 3004 3141 3815
New Hampshire 2514 2721 2671 2403 1919 2564 2128
Pennsylvania na na 1013 1277 1473 1876 1738
Rhode Island na na 803 812 898 949 639
West Virginia 1496 1381 1636 2384 2006 1966 1372
Kentucky 1772 1764 2741 1863 2796 2682 2247
New Mexico 902 858 595 787 865 717 74
Missouri 1002 997 118 1192 1131 124 1255
Ohio na na 1804 2198 2693 3254 2165
Wisconsin 286 244 267 293 575 586 625
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 5609 6697 5845 5976 6142 7078 6936
Massachusetts na na na na na na na
New Hampshire 5678 5968 6872 5883 5394 6787 6135
Pennsylvania na na 8374 9102 9010 10100 9983
Rhode Island na na 3567 3829 3527 3880 3262
West Virginia 4628 3889 4229 5489 4642 4832 4034
Kentucky 6756 6687 7517 6234 7613 8444 7205
New Mexico 5291 6842 7036 7402 7345 7672 7123
Missouri 3213 3235 3137 3373 3383 3421 3565
Ohio na na 8696 8789 9859 11432 9300
Wisconsin 2724 2661 3031 3291 4255 4633 5064
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
15 to 24
25 to 34
35 to 54
55 and up
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Male -140 7355 827 901 1286 -927 742 -758 1157 1241 1306 -829 146 301 1082 1242 1306 -1249
Female 841 5151 103 733 1257 -1521 659 -922 533 1204 1494 -1014 -132 1299 229 1331 1617 -1214
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 4888 4820 8365 9057 9873 11142 10110
Female 3201 3470 5257 5312 5701 6418 5442
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 3611 3879 3585 40 4496 5083 4662
Female 159 1695 1538 162 1816 2087 1875
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 2295 2328 2399 2658 2988 3379 2957
Female 839 828 936 957 1085 126 1107
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017 q1 q2 q3
All drug 3948 4061 6589 6894 7458 8430 7696 889150252325 1075831326045 167997701832
Heroin 1452 1472 1571 1681 1891 2173 191 302341597796 476222826087 215786123488
Opioid 2447 2636 2429 2636 2956 3382 3088 208009807928 283004552352 271305063812
Q12016-Q12017 Q22016-Q22017 Q32016-Q32017
All drug 889150252325 1075831326045 167997701832
Heroin 302341597796 476222826087 215786123488
Opioid 208009807928 283004552352 271305063812
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Heroin 136 674 701 1251 1486 -1209
Opioid 77 -785 853 1212 1442 -868
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Heroin 1452 1472 1571 1681 1891 2173 191
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Heroin 1452 1472 1571 1681 1891 2173 191
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Opioid 77 -785 853 1212 1442 -868
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Heroin 136 674 701 1251 1486 -1209
Q12016-Q12017 Q12016-Q12017 Q12016-Q12017
Q22016-Q22017 Q22016-Q22017 Q22016-Q22017
Q32016-Q32017 Q32016-Q32017 Q32016-Q32017
Page 34: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

Sample site report

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results All drug (11 sites)

0

10

20

30

40

50

60

70

80

90

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d al

l dru

g ov

erdo

se ra

tes

by

100

00 E

D v

isits

Quarter year

-2000

-1000

000

1000

2000

3000

4000

5000

6000

7000

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Opioid (11 sites)

0

5

10

15

20

25

30

35

40

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Heroin (11 sites)

0

5

10

15

20

25

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-15

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

Annual percentage changes (11 sites)

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Chart1

All drug
Heroin
Opioid
889150252325
302341597796
208009807928
1075831326045
476222826087
283004552352
167997701832
215786123488
271305063812

table with overall

table with overall

All drug
Suspected all drug overdose rates by 10000 ED visits

Sheet1

All drug

table by sex

Opioid
Quarter year
Suspected opioid overdose rates by 10000 ED visits

table by age

Opioid

table by state

Heroin
Quarter year
Suspected opioid overdose rates by 10000 ED visits
Heroin
All drug
Heroin
Opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Summary

Stable increases for all drug and heroin from Q1 2016 to Q3 2017- Opioid had stable increases from Q3 2016 to Q2 2017

Moderate decreases from Q2 to Q3 2017- 9 for all drug 9 for opioid and 12 for heroin

Annual percentage changes were above 15 increases- Q1 to Q1 89 all drug 30 heroin amp 21 opioid- Q2 to Q2 108 all drug 48 heroin amp 28 opioid- Q3 to Q3 17 all drug 22 heroin amp 27 opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency department data dissemination efforts

ldquoOpioid Overdoses Treated in Emergency Departmentsrdquo -httpswwwcdcgovvitalsignsopioid-overdosesindexhtml

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose

Reporting System

Presenter Julie OrsquoDonnell PhD MPHEpidemiologist

Centers for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Alana Vivolo-Kantor R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Julie OrsquoDonnell PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Increase in deaths outpaces increase in use

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid

overdose

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid overdose surveillance

Track specific substances contributing to overdose deaths

Detect newly-emerging substances involved in overdose

Determine risk factors circumstances associated with fatal overdose

Assess common drug combinations Provide more timely data on overdose deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

State Unintentional Drug Overdose Reporting System (SUDORS)

Death certificates

Medical examiner

coroner reportsToxicology

reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data submitted bi-annually

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

1 Data entry started

2 Data entry finished

1 Data entry started

2 Data entry finished

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS leverages National Violent Death Reporting System (NVDRS) platform

- Basic descriptors- Compare across demographics

- Recent release from institution- Overdose location - Survival time

- Mental health diagnoses- Substance abuse treatment history

- Substances present- Substances contributing to death

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Maine 1941 -1273 225 278 1523 -201 3951 -692 257 -813 2945 981 793 656 -299 -2255 3199 2197
Massachusetts na na na na na na 1561 -157 -848 -1148 311 1897 553 -31 -13 -1632 456 2146
New Hampshire 511 1514 -1438 -832 2583 -961 318 64 -433 -1791 2967 -876 825 -184 -1002 -2016 3363 -17
Pennsylvania na na 869 -102 1211 -116 na na 2979 1751 2589 -594 na na 2601 1534 2735 -735
Rhode Island na na 735 -790 1002 -1594 na na 28 454 544 -1191 na na 121 1057 566 -3262
West Virginia -1596 875 2978 -1543 409 -1651 -367 995 4331 -1664 402 -2377 -769 1847 4571 -1584 -199 -3022
Kentucky -102 1242 -1707 2211 1092 -1468 1095 5192 -2694 4045 352 -2002 -043 5541 -3206 5012 -408 -1624
New Mexico 2932 283 521 -078 445 -716 255 -1298 2611 151 -501 -1093 -487 -3061 3227 987 -1715 323
Missouri 068 -304 754 028 114 421 292 827 477 -177 954 767 -046 1839 096 -512 966 125
Ohio na na 107 1216 1596 -1865 na na 2274 2567 2167 -3194 na na 2182 2254 2086 -3348
Wisconsin -229 1388 861 2928 888 931 -948 986 1712 6728 322 314 -1457 91 983 9621 196 668
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 1514 2112 1966 2017 1853 2398 2634
Massachusetts 7036 8133 8006 7327 6486 6687 7956
New Hampshire 3806 3927 4179 3998 3282 4255 3882
Pennsylvania na na 1265 1641 1929 2428 2284
Rhode Island na na 1498 154 161 1698 1496
West Virginia 2258 2176 2392 3428 2857 2972 2266
Kentucky 2095 2325 3532 258 3624 3752 3001
New Mexico 1927 1976 1719 2168 2201 2091 1862
Missouri 1472 1515 1641 1719 1688 185 1991
Ohio na na 236 2897 3641 443 3015
Wisconsin 664 601 66 773 1294 1336 1377
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 502 9 959 931 721 952 1161
Massachusetts 4035 4258 4126 359 3004 3141 3815
New Hampshire 2514 2721 2671 2403 1919 2564 2128
Pennsylvania na na 1013 1277 1473 1876 1738
Rhode Island na na 803 812 898 949 639
West Virginia 1496 1381 1636 2384 2006 1966 1372
Kentucky 1772 1764 2741 1863 2796 2682 2247
New Mexico 902 858 595 787 865 717 74
Missouri 1002 997 118 1192 1131 124 1255
Ohio na na 1804 2198 2693 3254 2165
Wisconsin 286 244 267 293 575 586 625
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 5609 6697 5845 5976 6142 7078 6936
Massachusetts na na na na na na na
New Hampshire 5678 5968 6872 5883 5394 6787 6135
Pennsylvania na na 8374 9102 9010 10100 9983
Rhode Island na na 3567 3829 3527 3880 3262
West Virginia 4628 3889 4229 5489 4642 4832 4034
Kentucky 6756 6687 7517 6234 7613 8444 7205
New Mexico 5291 6842 7036 7402 7345 7672 7123
Missouri 3213 3235 3137 3373 3383 3421 3565
Ohio na na 8696 8789 9859 11432 9300
Wisconsin 2724 2661 3031 3291 4255 4633 5064
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
15 to 24
25 to 34
35 to 54
55 and up
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Male -140 7355 827 901 1286 -927 742 -758 1157 1241 1306 -829 146 301 1082 1242 1306 -1249
Female 841 5151 103 733 1257 -1521 659 -922 533 1204 1494 -1014 -132 1299 229 1331 1617 -1214
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 4888 4820 8365 9057 9873 11142 10110
Female 3201 3470 5257 5312 5701 6418 5442
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 3611 3879 3585 40 4496 5083 4662
Female 159 1695 1538 162 1816 2087 1875
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 2295 2328 2399 2658 2988 3379 2957
Female 839 828 936 957 1085 126 1107
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017 q1 q2 q3
All drug 3948 4061 6589 6894 7458 8430 7696 889150252325 1075831326045 167997701832
Heroin 1452 1472 1571 1681 1891 2173 191 302341597796 476222826087 215786123488
Opioid 2447 2636 2429 2636 2956 3382 3088 208009807928 283004552352 271305063812
Q12016-Q12017 Q22016-Q22017 Q32016-Q32017
All drug 889150252325 1075831326045 167997701832
Heroin 302341597796 476222826087 215786123488
Opioid 208009807928 283004552352 271305063812
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Heroin 136 674 701 1251 1486 -1209
Opioid 77 -785 853 1212 1442 -868
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Heroin 1452 1472 1571 1681 1891 2173 191
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Heroin 1452 1472 1571 1681 1891 2173 191
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Opioid 77 -785 853 1212 1442 -868
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Heroin 136 674 701 1251 1486 -1209
Q12016-Q12017 Q12016-Q12017 Q12016-Q12017
Q22016-Q22017 Q22016-Q22017 Q22016-Q22017
Q32016-Q32017 Q32016-Q32017 Q32016-Q32017
Page 35: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results All drug (11 sites)

0

10

20

30

40

50

60

70

80

90

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d al

l dru

g ov

erdo

se ra

tes

by

100

00 E

D v

isits

Quarter year

-2000

-1000

000

1000

2000

3000

4000

5000

6000

7000

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Opioid (11 sites)

0

5

10

15

20

25

30

35

40

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Heroin (11 sites)

0

5

10

15

20

25

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-15

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

Annual percentage changes (11 sites)

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Chart1

All drug
Heroin
Opioid
889150252325
302341597796
208009807928
1075831326045
476222826087
283004552352
167997701832
215786123488
271305063812

table with overall

table with overall

All drug
Suspected all drug overdose rates by 10000 ED visits

Sheet1

All drug

table by sex

Opioid
Quarter year
Suspected opioid overdose rates by 10000 ED visits

table by age

Opioid

table by state

Heroin
Quarter year
Suspected opioid overdose rates by 10000 ED visits
Heroin
All drug
Heroin
Opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Summary

Stable increases for all drug and heroin from Q1 2016 to Q3 2017- Opioid had stable increases from Q3 2016 to Q2 2017

Moderate decreases from Q2 to Q3 2017- 9 for all drug 9 for opioid and 12 for heroin

Annual percentage changes were above 15 increases- Q1 to Q1 89 all drug 30 heroin amp 21 opioid- Q2 to Q2 108 all drug 48 heroin amp 28 opioid- Q3 to Q3 17 all drug 22 heroin amp 27 opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency department data dissemination efforts

ldquoOpioid Overdoses Treated in Emergency Departmentsrdquo -httpswwwcdcgovvitalsignsopioid-overdosesindexhtml

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose

Reporting System

Presenter Julie OrsquoDonnell PhD MPHEpidemiologist

Centers for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Alana Vivolo-Kantor R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Julie OrsquoDonnell PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Increase in deaths outpaces increase in use

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid

overdose

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid overdose surveillance

Track specific substances contributing to overdose deaths

Detect newly-emerging substances involved in overdose

Determine risk factors circumstances associated with fatal overdose

Assess common drug combinations Provide more timely data on overdose deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

State Unintentional Drug Overdose Reporting System (SUDORS)

Death certificates

Medical examiner

coroner reportsToxicology

reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data submitted bi-annually

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

1 Data entry started

2 Data entry finished

1 Data entry started

2 Data entry finished

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS leverages National Violent Death Reporting System (NVDRS) platform

- Basic descriptors- Compare across demographics

- Recent release from institution- Overdose location - Survival time

- Mental health diagnoses- Substance abuse treatment history

- Substances present- Substances contributing to death

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Maine 1941 -1273 225 278 1523 -201 3951 -692 257 -813 2945 981 793 656 -299 -2255 3199 2197
Massachusetts na na na na na na 1561 -157 -848 -1148 311 1897 553 -31 -13 -1632 456 2146
New Hampshire 511 1514 -1438 -832 2583 -961 318 64 -433 -1791 2967 -876 825 -184 -1002 -2016 3363 -17
Pennsylvania na na 869 -102 1211 -116 na na 2979 1751 2589 -594 na na 2601 1534 2735 -735
Rhode Island na na 735 -790 1002 -1594 na na 28 454 544 -1191 na na 121 1057 566 -3262
West Virginia -1596 875 2978 -1543 409 -1651 -367 995 4331 -1664 402 -2377 -769 1847 4571 -1584 -199 -3022
Kentucky -102 1242 -1707 2211 1092 -1468 1095 5192 -2694 4045 352 -2002 -043 5541 -3206 5012 -408 -1624
New Mexico 2932 283 521 -078 445 -716 255 -1298 2611 151 -501 -1093 -487 -3061 3227 987 -1715 323
Missouri 068 -304 754 028 114 421 292 827 477 -177 954 767 -046 1839 096 -512 966 125
Ohio na na 107 1216 1596 -1865 na na 2274 2567 2167 -3194 na na 2182 2254 2086 -3348
Wisconsin -229 1388 861 2928 888 931 -948 986 1712 6728 322 314 -1457 91 983 9621 196 668
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 1514 2112 1966 2017 1853 2398 2634
Massachusetts 7036 8133 8006 7327 6486 6687 7956
New Hampshire 3806 3927 4179 3998 3282 4255 3882
Pennsylvania na na 1265 1641 1929 2428 2284
Rhode Island na na 1498 154 161 1698 1496
West Virginia 2258 2176 2392 3428 2857 2972 2266
Kentucky 2095 2325 3532 258 3624 3752 3001
New Mexico 1927 1976 1719 2168 2201 2091 1862
Missouri 1472 1515 1641 1719 1688 185 1991
Ohio na na 236 2897 3641 443 3015
Wisconsin 664 601 66 773 1294 1336 1377
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 502 9 959 931 721 952 1161
Massachusetts 4035 4258 4126 359 3004 3141 3815
New Hampshire 2514 2721 2671 2403 1919 2564 2128
Pennsylvania na na 1013 1277 1473 1876 1738
Rhode Island na na 803 812 898 949 639
West Virginia 1496 1381 1636 2384 2006 1966 1372
Kentucky 1772 1764 2741 1863 2796 2682 2247
New Mexico 902 858 595 787 865 717 74
Missouri 1002 997 118 1192 1131 124 1255
Ohio na na 1804 2198 2693 3254 2165
Wisconsin 286 244 267 293 575 586 625
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 5609 6697 5845 5976 6142 7078 6936
Massachusetts na na na na na na na
New Hampshire 5678 5968 6872 5883 5394 6787 6135
Pennsylvania na na 8374 9102 9010 10100 9983
Rhode Island na na 3567 3829 3527 3880 3262
West Virginia 4628 3889 4229 5489 4642 4832 4034
Kentucky 6756 6687 7517 6234 7613 8444 7205
New Mexico 5291 6842 7036 7402 7345 7672 7123
Missouri 3213 3235 3137 3373 3383 3421 3565
Ohio na na 8696 8789 9859 11432 9300
Wisconsin 2724 2661 3031 3291 4255 4633 5064
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
15 to 24
25 to 34
35 to 54
55 and up
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Male -140 7355 827 901 1286 -927 742 -758 1157 1241 1306 -829 146 301 1082 1242 1306 -1249
Female 841 5151 103 733 1257 -1521 659 -922 533 1204 1494 -1014 -132 1299 229 1331 1617 -1214
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 4888 4820 8365 9057 9873 11142 10110
Female 3201 3470 5257 5312 5701 6418 5442
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 3611 3879 3585 40 4496 5083 4662
Female 159 1695 1538 162 1816 2087 1875
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 2295 2328 2399 2658 2988 3379 2957
Female 839 828 936 957 1085 126 1107
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017 q1 q2 q3
All drug 3948 4061 6589 6894 7458 8430 7696 889150252325 1075831326045 167997701832
Heroin 1452 1472 1571 1681 1891 2173 191 302341597796 476222826087 215786123488
Opioid 2447 2636 2429 2636 2956 3382 3088 208009807928 283004552352 271305063812
Q12016-Q12017 Q22016-Q22017 Q32016-Q32017
All drug 889150252325 1075831326045 167997701832
Heroin 302341597796 476222826087 215786123488
Opioid 208009807928 283004552352 271305063812
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Heroin 136 674 701 1251 1486 -1209
Opioid 77 -785 853 1212 1442 -868
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Heroin 1452 1472 1571 1681 1891 2173 191
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Heroin 1452 1472 1571 1681 1891 2173 191
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Opioid 77 -785 853 1212 1442 -868
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Heroin 136 674 701 1251 1486 -1209
Q12016-Q12017 Q12016-Q12017 Q12016-Q12017
Q22016-Q22017 Q22016-Q22017 Q22016-Q22017
Q32016-Q32017 Q32016-Q32017 Q32016-Q32017
Page 36: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Opioid (11 sites)

0

5

10

15

20

25

30

35

40

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Heroin (11 sites)

0

5

10

15

20

25

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-15

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

Annual percentage changes (11 sites)

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Chart1

All drug
Heroin
Opioid
889150252325
302341597796
208009807928
1075831326045
476222826087
283004552352
167997701832
215786123488
271305063812

table with overall

table with overall

All drug
Suspected all drug overdose rates by 10000 ED visits

Sheet1

All drug

table by sex

Opioid
Quarter year
Suspected opioid overdose rates by 10000 ED visits

table by age

Opioid

table by state

Heroin
Quarter year
Suspected opioid overdose rates by 10000 ED visits
Heroin
All drug
Heroin
Opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Summary

Stable increases for all drug and heroin from Q1 2016 to Q3 2017- Opioid had stable increases from Q3 2016 to Q2 2017

Moderate decreases from Q2 to Q3 2017- 9 for all drug 9 for opioid and 12 for heroin

Annual percentage changes were above 15 increases- Q1 to Q1 89 all drug 30 heroin amp 21 opioid- Q2 to Q2 108 all drug 48 heroin amp 28 opioid- Q3 to Q3 17 all drug 22 heroin amp 27 opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency department data dissemination efforts

ldquoOpioid Overdoses Treated in Emergency Departmentsrdquo -httpswwwcdcgovvitalsignsopioid-overdosesindexhtml

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose

Reporting System

Presenter Julie OrsquoDonnell PhD MPHEpidemiologist

Centers for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Alana Vivolo-Kantor R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Julie OrsquoDonnell PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Increase in deaths outpaces increase in use

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid

overdose

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid overdose surveillance

Track specific substances contributing to overdose deaths

Detect newly-emerging substances involved in overdose

Determine risk factors circumstances associated with fatal overdose

Assess common drug combinations Provide more timely data on overdose deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

State Unintentional Drug Overdose Reporting System (SUDORS)

Death certificates

Medical examiner

coroner reportsToxicology

reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data submitted bi-annually

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

1 Data entry started

2 Data entry finished

1 Data entry started

2 Data entry finished

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS leverages National Violent Death Reporting System (NVDRS) platform

- Basic descriptors- Compare across demographics

- Recent release from institution- Overdose location - Survival time

- Mental health diagnoses- Substance abuse treatment history

- Substances present- Substances contributing to death

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Maine 1941 -1273 225 278 1523 -201 3951 -692 257 -813 2945 981 793 656 -299 -2255 3199 2197
Massachusetts na na na na na na 1561 -157 -848 -1148 311 1897 553 -31 -13 -1632 456 2146
New Hampshire 511 1514 -1438 -832 2583 -961 318 64 -433 -1791 2967 -876 825 -184 -1002 -2016 3363 -17
Pennsylvania na na 869 -102 1211 -116 na na 2979 1751 2589 -594 na na 2601 1534 2735 -735
Rhode Island na na 735 -790 1002 -1594 na na 28 454 544 -1191 na na 121 1057 566 -3262
West Virginia -1596 875 2978 -1543 409 -1651 -367 995 4331 -1664 402 -2377 -769 1847 4571 -1584 -199 -3022
Kentucky -102 1242 -1707 2211 1092 -1468 1095 5192 -2694 4045 352 -2002 -043 5541 -3206 5012 -408 -1624
New Mexico 2932 283 521 -078 445 -716 255 -1298 2611 151 -501 -1093 -487 -3061 3227 987 -1715 323
Missouri 068 -304 754 028 114 421 292 827 477 -177 954 767 -046 1839 096 -512 966 125
Ohio na na 107 1216 1596 -1865 na na 2274 2567 2167 -3194 na na 2182 2254 2086 -3348
Wisconsin -229 1388 861 2928 888 931 -948 986 1712 6728 322 314 -1457 91 983 9621 196 668
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 1514 2112 1966 2017 1853 2398 2634
Massachusetts 7036 8133 8006 7327 6486 6687 7956
New Hampshire 3806 3927 4179 3998 3282 4255 3882
Pennsylvania na na 1265 1641 1929 2428 2284
Rhode Island na na 1498 154 161 1698 1496
West Virginia 2258 2176 2392 3428 2857 2972 2266
Kentucky 2095 2325 3532 258 3624 3752 3001
New Mexico 1927 1976 1719 2168 2201 2091 1862
Missouri 1472 1515 1641 1719 1688 185 1991
Ohio na na 236 2897 3641 443 3015
Wisconsin 664 601 66 773 1294 1336 1377
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 502 9 959 931 721 952 1161
Massachusetts 4035 4258 4126 359 3004 3141 3815
New Hampshire 2514 2721 2671 2403 1919 2564 2128
Pennsylvania na na 1013 1277 1473 1876 1738
Rhode Island na na 803 812 898 949 639
West Virginia 1496 1381 1636 2384 2006 1966 1372
Kentucky 1772 1764 2741 1863 2796 2682 2247
New Mexico 902 858 595 787 865 717 74
Missouri 1002 997 118 1192 1131 124 1255
Ohio na na 1804 2198 2693 3254 2165
Wisconsin 286 244 267 293 575 586 625
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 5609 6697 5845 5976 6142 7078 6936
Massachusetts na na na na na na na
New Hampshire 5678 5968 6872 5883 5394 6787 6135
Pennsylvania na na 8374 9102 9010 10100 9983
Rhode Island na na 3567 3829 3527 3880 3262
West Virginia 4628 3889 4229 5489 4642 4832 4034
Kentucky 6756 6687 7517 6234 7613 8444 7205
New Mexico 5291 6842 7036 7402 7345 7672 7123
Missouri 3213 3235 3137 3373 3383 3421 3565
Ohio na na 8696 8789 9859 11432 9300
Wisconsin 2724 2661 3031 3291 4255 4633 5064
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
15 to 24
25 to 34
35 to 54
55 and up
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Male -140 7355 827 901 1286 -927 742 -758 1157 1241 1306 -829 146 301 1082 1242 1306 -1249
Female 841 5151 103 733 1257 -1521 659 -922 533 1204 1494 -1014 -132 1299 229 1331 1617 -1214
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 4888 4820 8365 9057 9873 11142 10110
Female 3201 3470 5257 5312 5701 6418 5442
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 3611 3879 3585 40 4496 5083 4662
Female 159 1695 1538 162 1816 2087 1875
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 2295 2328 2399 2658 2988 3379 2957
Female 839 828 936 957 1085 126 1107
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017 q1 q2 q3
All drug 3948 4061 6589 6894 7458 8430 7696 889150252325 1075831326045 167997701832
Heroin 1452 1472 1571 1681 1891 2173 191 302341597796 476222826087 215786123488
Opioid 2447 2636 2429 2636 2956 3382 3088 208009807928 283004552352 271305063812
Q12016-Q12017 Q22016-Q22017 Q32016-Q32017
All drug 889150252325 1075831326045 167997701832
Heroin 302341597796 476222826087 215786123488
Opioid 208009807928 283004552352 271305063812
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Heroin 136 674 701 1251 1486 -1209
Opioid 77 -785 853 1212 1442 -868
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Heroin 1452 1472 1571 1681 1891 2173 191
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Heroin 1452 1472 1571 1681 1891 2173 191
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Opioid 77 -785 853 1212 1442 -868
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Heroin 136 674 701 1251 1486 -1209
Q12016-Q12017 Q12016-Q12017 Q12016-Q12017
Q22016-Q22017 Q22016-Q22017 Q22016-Q22017
Q32016-Q32017 Q32016-Q32017 Q32016-Q32017
Page 37: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

ED results Heroin (11 sites)

0

5

10

15

20

25

Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017

Susp

ecte

d op

ioid

ove

rdos

e ra

tes

by

100

00 E

D v

isits

Quarter year

-15

-10

-5

0

5

10

15

20

Δ fromQ1-Q2 2016

Δ fromQ2-Q3 2016

Δ fromQ3-Q4 2016

Δ fromQ4 2016-Q1

2017

Δ fromQ1-Q2 2017

Δ fromQ2-Q3 2017

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Rx Summit wwwNationalRxDrugAbuseSummitorg

Annual percentage changes (11 sites)

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Chart1

All drug
Heroin
Opioid
889150252325
302341597796
208009807928
1075831326045
476222826087
283004552352
167997701832
215786123488
271305063812

table with overall

table with overall

All drug
Suspected all drug overdose rates by 10000 ED visits

Sheet1

All drug

table by sex

Opioid
Quarter year
Suspected opioid overdose rates by 10000 ED visits

table by age

Opioid

table by state

Heroin
Quarter year
Suspected opioid overdose rates by 10000 ED visits
Heroin
All drug
Heroin
Opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Summary

Stable increases for all drug and heroin from Q1 2016 to Q3 2017- Opioid had stable increases from Q3 2016 to Q2 2017

Moderate decreases from Q2 to Q3 2017- 9 for all drug 9 for opioid and 12 for heroin

Annual percentage changes were above 15 increases- Q1 to Q1 89 all drug 30 heroin amp 21 opioid- Q2 to Q2 108 all drug 48 heroin amp 28 opioid- Q3 to Q3 17 all drug 22 heroin amp 27 opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency department data dissemination efforts

ldquoOpioid Overdoses Treated in Emergency Departmentsrdquo -httpswwwcdcgovvitalsignsopioid-overdosesindexhtml

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose

Reporting System

Presenter Julie OrsquoDonnell PhD MPHEpidemiologist

Centers for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Alana Vivolo-Kantor R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Julie OrsquoDonnell PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Increase in deaths outpaces increase in use

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid

overdose

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid overdose surveillance

Track specific substances contributing to overdose deaths

Detect newly-emerging substances involved in overdose

Determine risk factors circumstances associated with fatal overdose

Assess common drug combinations Provide more timely data on overdose deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

State Unintentional Drug Overdose Reporting System (SUDORS)

Death certificates

Medical examiner

coroner reportsToxicology

reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data submitted bi-annually

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

1 Data entry started

2 Data entry finished

1 Data entry started

2 Data entry finished

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS leverages National Violent Death Reporting System (NVDRS) platform

- Basic descriptors- Compare across demographics

- Recent release from institution- Overdose location - Survival time

- Mental health diagnoses- Substance abuse treatment history

- Substances present- Substances contributing to death

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Maine 1941 -1273 225 278 1523 -201 3951 -692 257 -813 2945 981 793 656 -299 -2255 3199 2197
Massachusetts na na na na na na 1561 -157 -848 -1148 311 1897 553 -31 -13 -1632 456 2146
New Hampshire 511 1514 -1438 -832 2583 -961 318 64 -433 -1791 2967 -876 825 -184 -1002 -2016 3363 -17
Pennsylvania na na 869 -102 1211 -116 na na 2979 1751 2589 -594 na na 2601 1534 2735 -735
Rhode Island na na 735 -790 1002 -1594 na na 28 454 544 -1191 na na 121 1057 566 -3262
West Virginia -1596 875 2978 -1543 409 -1651 -367 995 4331 -1664 402 -2377 -769 1847 4571 -1584 -199 -3022
Kentucky -102 1242 -1707 2211 1092 -1468 1095 5192 -2694 4045 352 -2002 -043 5541 -3206 5012 -408 -1624
New Mexico 2932 283 521 -078 445 -716 255 -1298 2611 151 -501 -1093 -487 -3061 3227 987 -1715 323
Missouri 068 -304 754 028 114 421 292 827 477 -177 954 767 -046 1839 096 -512 966 125
Ohio na na 107 1216 1596 -1865 na na 2274 2567 2167 -3194 na na 2182 2254 2086 -3348
Wisconsin -229 1388 861 2928 888 931 -948 986 1712 6728 322 314 -1457 91 983 9621 196 668
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 1514 2112 1966 2017 1853 2398 2634
Massachusetts 7036 8133 8006 7327 6486 6687 7956
New Hampshire 3806 3927 4179 3998 3282 4255 3882
Pennsylvania na na 1265 1641 1929 2428 2284
Rhode Island na na 1498 154 161 1698 1496
West Virginia 2258 2176 2392 3428 2857 2972 2266
Kentucky 2095 2325 3532 258 3624 3752 3001
New Mexico 1927 1976 1719 2168 2201 2091 1862
Missouri 1472 1515 1641 1719 1688 185 1991
Ohio na na 236 2897 3641 443 3015
Wisconsin 664 601 66 773 1294 1336 1377
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 502 9 959 931 721 952 1161
Massachusetts 4035 4258 4126 359 3004 3141 3815
New Hampshire 2514 2721 2671 2403 1919 2564 2128
Pennsylvania na na 1013 1277 1473 1876 1738
Rhode Island na na 803 812 898 949 639
West Virginia 1496 1381 1636 2384 2006 1966 1372
Kentucky 1772 1764 2741 1863 2796 2682 2247
New Mexico 902 858 595 787 865 717 74
Missouri 1002 997 118 1192 1131 124 1255
Ohio na na 1804 2198 2693 3254 2165
Wisconsin 286 244 267 293 575 586 625
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 5609 6697 5845 5976 6142 7078 6936
Massachusetts na na na na na na na
New Hampshire 5678 5968 6872 5883 5394 6787 6135
Pennsylvania na na 8374 9102 9010 10100 9983
Rhode Island na na 3567 3829 3527 3880 3262
West Virginia 4628 3889 4229 5489 4642 4832 4034
Kentucky 6756 6687 7517 6234 7613 8444 7205
New Mexico 5291 6842 7036 7402 7345 7672 7123
Missouri 3213 3235 3137 3373 3383 3421 3565
Ohio na na 8696 8789 9859 11432 9300
Wisconsin 2724 2661 3031 3291 4255 4633 5064
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
15 to 24
25 to 34
35 to 54
55 and up
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Male -140 7355 827 901 1286 -927 742 -758 1157 1241 1306 -829 146 301 1082 1242 1306 -1249
Female 841 5151 103 733 1257 -1521 659 -922 533 1204 1494 -1014 -132 1299 229 1331 1617 -1214
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 4888 4820 8365 9057 9873 11142 10110
Female 3201 3470 5257 5312 5701 6418 5442
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 3611 3879 3585 40 4496 5083 4662
Female 159 1695 1538 162 1816 2087 1875
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 2295 2328 2399 2658 2988 3379 2957
Female 839 828 936 957 1085 126 1107
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017 q1 q2 q3
All drug 3948 4061 6589 6894 7458 8430 7696 889150252325 1075831326045 167997701832
Heroin 1452 1472 1571 1681 1891 2173 191 302341597796 476222826087 215786123488
Opioid 2447 2636 2429 2636 2956 3382 3088 208009807928 283004552352 271305063812
Q12016-Q12017 Q22016-Q22017 Q32016-Q32017
All drug 889150252325 1075831326045 167997701832
Heroin 302341597796 476222826087 215786123488
Opioid 208009807928 283004552352 271305063812
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Heroin 136 674 701 1251 1486 -1209
Opioid 77 -785 853 1212 1442 -868
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Heroin 1452 1472 1571 1681 1891 2173 191
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Heroin 1452 1472 1571 1681 1891 2173 191
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Opioid 77 -785 853 1212 1442 -868
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Heroin 136 674 701 1251 1486 -1209
Q12016-Q12017 Q12016-Q12017 Q12016-Q12017
Q22016-Q22017 Q22016-Q22017 Q22016-Q22017
Q32016-Q32017 Q32016-Q32017 Q32016-Q32017
Page 38: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

Annual percentage changes (11 sites)

Kentucky Maine Massachusetts Missouri New Hampshire New Mexico Ohio Pennsylvania Rhode Island West Virginia Wisconsin

Chart1

All drug
Heroin
Opioid
889150252325
302341597796
208009807928
1075831326045
476222826087
283004552352
167997701832
215786123488
271305063812

table with overall

table with overall

All drug
Suspected all drug overdose rates by 10000 ED visits

Sheet1

All drug

table by sex

Opioid
Quarter year
Suspected opioid overdose rates by 10000 ED visits

table by age

Opioid

table by state

Heroin
Quarter year
Suspected opioid overdose rates by 10000 ED visits
Heroin
All drug
Heroin
Opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Summary

Stable increases for all drug and heroin from Q1 2016 to Q3 2017- Opioid had stable increases from Q3 2016 to Q2 2017

Moderate decreases from Q2 to Q3 2017- 9 for all drug 9 for opioid and 12 for heroin

Annual percentage changes were above 15 increases- Q1 to Q1 89 all drug 30 heroin amp 21 opioid- Q2 to Q2 108 all drug 48 heroin amp 28 opioid- Q3 to Q3 17 all drug 22 heroin amp 27 opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency department data dissemination efforts

ldquoOpioid Overdoses Treated in Emergency Departmentsrdquo -httpswwwcdcgovvitalsignsopioid-overdosesindexhtml

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose

Reporting System

Presenter Julie OrsquoDonnell PhD MPHEpidemiologist

Centers for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Alana Vivolo-Kantor R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Julie OrsquoDonnell PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Increase in deaths outpaces increase in use

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid

overdose

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid overdose surveillance

Track specific substances contributing to overdose deaths

Detect newly-emerging substances involved in overdose

Determine risk factors circumstances associated with fatal overdose

Assess common drug combinations Provide more timely data on overdose deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

State Unintentional Drug Overdose Reporting System (SUDORS)

Death certificates

Medical examiner

coroner reportsToxicology

reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data submitted bi-annually

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

1 Data entry started

2 Data entry finished

1 Data entry started

2 Data entry finished

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS leverages National Violent Death Reporting System (NVDRS) platform

- Basic descriptors- Compare across demographics

- Recent release from institution- Overdose location - Survival time

- Mental health diagnoses- Substance abuse treatment history

- Substances present- Substances contributing to death

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Maine 1941 -1273 225 278 1523 -201 3951 -692 257 -813 2945 981 793 656 -299 -2255 3199 2197
Massachusetts na na na na na na 1561 -157 -848 -1148 311 1897 553 -31 -13 -1632 456 2146
New Hampshire 511 1514 -1438 -832 2583 -961 318 64 -433 -1791 2967 -876 825 -184 -1002 -2016 3363 -17
Pennsylvania na na 869 -102 1211 -116 na na 2979 1751 2589 -594 na na 2601 1534 2735 -735
Rhode Island na na 735 -790 1002 -1594 na na 28 454 544 -1191 na na 121 1057 566 -3262
West Virginia -1596 875 2978 -1543 409 -1651 -367 995 4331 -1664 402 -2377 -769 1847 4571 -1584 -199 -3022
Kentucky -102 1242 -1707 2211 1092 -1468 1095 5192 -2694 4045 352 -2002 -043 5541 -3206 5012 -408 -1624
New Mexico 2932 283 521 -078 445 -716 255 -1298 2611 151 -501 -1093 -487 -3061 3227 987 -1715 323
Missouri 068 -304 754 028 114 421 292 827 477 -177 954 767 -046 1839 096 -512 966 125
Ohio na na 107 1216 1596 -1865 na na 2274 2567 2167 -3194 na na 2182 2254 2086 -3348
Wisconsin -229 1388 861 2928 888 931 -948 986 1712 6728 322 314 -1457 91 983 9621 196 668
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 1514 2112 1966 2017 1853 2398 2634
Massachusetts 7036 8133 8006 7327 6486 6687 7956
New Hampshire 3806 3927 4179 3998 3282 4255 3882
Pennsylvania na na 1265 1641 1929 2428 2284
Rhode Island na na 1498 154 161 1698 1496
West Virginia 2258 2176 2392 3428 2857 2972 2266
Kentucky 2095 2325 3532 258 3624 3752 3001
New Mexico 1927 1976 1719 2168 2201 2091 1862
Missouri 1472 1515 1641 1719 1688 185 1991
Ohio na na 236 2897 3641 443 3015
Wisconsin 664 601 66 773 1294 1336 1377
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 502 9 959 931 721 952 1161
Massachusetts 4035 4258 4126 359 3004 3141 3815
New Hampshire 2514 2721 2671 2403 1919 2564 2128
Pennsylvania na na 1013 1277 1473 1876 1738
Rhode Island na na 803 812 898 949 639
West Virginia 1496 1381 1636 2384 2006 1966 1372
Kentucky 1772 1764 2741 1863 2796 2682 2247
New Mexico 902 858 595 787 865 717 74
Missouri 1002 997 118 1192 1131 124 1255
Ohio na na 1804 2198 2693 3254 2165
Wisconsin 286 244 267 293 575 586 625
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 5609 6697 5845 5976 6142 7078 6936
Massachusetts na na na na na na na
New Hampshire 5678 5968 6872 5883 5394 6787 6135
Pennsylvania na na 8374 9102 9010 10100 9983
Rhode Island na na 3567 3829 3527 3880 3262
West Virginia 4628 3889 4229 5489 4642 4832 4034
Kentucky 6756 6687 7517 6234 7613 8444 7205
New Mexico 5291 6842 7036 7402 7345 7672 7123
Missouri 3213 3235 3137 3373 3383 3421 3565
Ohio na na 8696 8789 9859 11432 9300
Wisconsin 2724 2661 3031 3291 4255 4633 5064
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
15 to 24
25 to 34
35 to 54
55 and up
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Male -140 7355 827 901 1286 -927 742 -758 1157 1241 1306 -829 146 301 1082 1242 1306 -1249
Female 841 5151 103 733 1257 -1521 659 -922 533 1204 1494 -1014 -132 1299 229 1331 1617 -1214
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 4888 4820 8365 9057 9873 11142 10110
Female 3201 3470 5257 5312 5701 6418 5442
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 3611 3879 3585 40 4496 5083 4662
Female 159 1695 1538 162 1816 2087 1875
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 2295 2328 2399 2658 2988 3379 2957
Female 839 828 936 957 1085 126 1107
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017 q1 q2 q3
All drug 3948 4061 6589 6894 7458 8430 7696 889150252325 1075831326045 167997701832
Heroin 1452 1472 1571 1681 1891 2173 191 302341597796 476222826087 215786123488
Opioid 2447 2636 2429 2636 2956 3382 3088 208009807928 283004552352 271305063812
Q12016-Q12017 Q22016-Q22017 Q32016-Q32017
All drug 889150252325 1075831326045 167997701832
Heroin 302341597796 476222826087 215786123488
Opioid 208009807928 283004552352 271305063812
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Heroin 136 674 701 1251 1486 -1209
Opioid 77 -785 853 1212 1442 -868
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Heroin 1452 1472 1571 1681 1891 2173 191
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Heroin 1452 1472 1571 1681 1891 2173 191
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Opioid 77 -785 853 1212 1442 -868
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Heroin 136 674 701 1251 1486 -1209
Q12016-Q12017 Q12016-Q12017 Q12016-Q12017
Q22016-Q22017 Q22016-Q22017 Q22016-Q22017
Q32016-Q32017 Q32016-Q32017 Q32016-Q32017
Page 39: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Chart1

All drug
Heroin
Opioid
889150252325
302341597796
208009807928
1075831326045
476222826087
283004552352
167997701832
215786123488
271305063812

table with overall

table with overall

All drug
Suspected all drug overdose rates by 10000 ED visits

Sheet1

All drug

table by sex

Opioid
Quarter year
Suspected opioid overdose rates by 10000 ED visits

table by age

Opioid

table by state

Heroin
Quarter year
Suspected opioid overdose rates by 10000 ED visits
Heroin
All drug
Heroin
Opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Summary

Stable increases for all drug and heroin from Q1 2016 to Q3 2017- Opioid had stable increases from Q3 2016 to Q2 2017

Moderate decreases from Q2 to Q3 2017- 9 for all drug 9 for opioid and 12 for heroin

Annual percentage changes were above 15 increases- Q1 to Q1 89 all drug 30 heroin amp 21 opioid- Q2 to Q2 108 all drug 48 heroin amp 28 opioid- Q3 to Q3 17 all drug 22 heroin amp 27 opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency department data dissemination efforts

ldquoOpioid Overdoses Treated in Emergency Departmentsrdquo -httpswwwcdcgovvitalsignsopioid-overdosesindexhtml

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose

Reporting System

Presenter Julie OrsquoDonnell PhD MPHEpidemiologist

Centers for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Alana Vivolo-Kantor R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Julie OrsquoDonnell PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Increase in deaths outpaces increase in use

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid

overdose

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid overdose surveillance

Track specific substances contributing to overdose deaths

Detect newly-emerging substances involved in overdose

Determine risk factors circumstances associated with fatal overdose

Assess common drug combinations Provide more timely data on overdose deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

State Unintentional Drug Overdose Reporting System (SUDORS)

Death certificates

Medical examiner

coroner reportsToxicology

reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data submitted bi-annually

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

1 Data entry started

2 Data entry finished

1 Data entry started

2 Data entry finished

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS leverages National Violent Death Reporting System (NVDRS) platform

- Basic descriptors- Compare across demographics

- Recent release from institution- Overdose location - Survival time

- Mental health diagnoses- Substance abuse treatment history

- Substances present- Substances contributing to death

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Maine 1941 -1273 225 278 1523 -201 3951 -692 257 -813 2945 981 793 656 -299 -2255 3199 2197
Massachusetts na na na na na na 1561 -157 -848 -1148 311 1897 553 -31 -13 -1632 456 2146
New Hampshire 511 1514 -1438 -832 2583 -961 318 64 -433 -1791 2967 -876 825 -184 -1002 -2016 3363 -17
Pennsylvania na na 869 -102 1211 -116 na na 2979 1751 2589 -594 na na 2601 1534 2735 -735
Rhode Island na na 735 -790 1002 -1594 na na 28 454 544 -1191 na na 121 1057 566 -3262
West Virginia -1596 875 2978 -1543 409 -1651 -367 995 4331 -1664 402 -2377 -769 1847 4571 -1584 -199 -3022
Kentucky -102 1242 -1707 2211 1092 -1468 1095 5192 -2694 4045 352 -2002 -043 5541 -3206 5012 -408 -1624
New Mexico 2932 283 521 -078 445 -716 255 -1298 2611 151 -501 -1093 -487 -3061 3227 987 -1715 323
Missouri 068 -304 754 028 114 421 292 827 477 -177 954 767 -046 1839 096 -512 966 125
Ohio na na 107 1216 1596 -1865 na na 2274 2567 2167 -3194 na na 2182 2254 2086 -3348
Wisconsin -229 1388 861 2928 888 931 -948 986 1712 6728 322 314 -1457 91 983 9621 196 668
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 1514 2112 1966 2017 1853 2398 2634
Massachusetts 7036 8133 8006 7327 6486 6687 7956
New Hampshire 3806 3927 4179 3998 3282 4255 3882
Pennsylvania na na 1265 1641 1929 2428 2284
Rhode Island na na 1498 154 161 1698 1496
West Virginia 2258 2176 2392 3428 2857 2972 2266
Kentucky 2095 2325 3532 258 3624 3752 3001
New Mexico 1927 1976 1719 2168 2201 2091 1862
Missouri 1472 1515 1641 1719 1688 185 1991
Ohio na na 236 2897 3641 443 3015
Wisconsin 664 601 66 773 1294 1336 1377
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 502 9 959 931 721 952 1161
Massachusetts 4035 4258 4126 359 3004 3141 3815
New Hampshire 2514 2721 2671 2403 1919 2564 2128
Pennsylvania na na 1013 1277 1473 1876 1738
Rhode Island na na 803 812 898 949 639
West Virginia 1496 1381 1636 2384 2006 1966 1372
Kentucky 1772 1764 2741 1863 2796 2682 2247
New Mexico 902 858 595 787 865 717 74
Missouri 1002 997 118 1192 1131 124 1255
Ohio na na 1804 2198 2693 3254 2165
Wisconsin 286 244 267 293 575 586 625
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 5609 6697 5845 5976 6142 7078 6936
Massachusetts na na na na na na na
New Hampshire 5678 5968 6872 5883 5394 6787 6135
Pennsylvania na na 8374 9102 9010 10100 9983
Rhode Island na na 3567 3829 3527 3880 3262
West Virginia 4628 3889 4229 5489 4642 4832 4034
Kentucky 6756 6687 7517 6234 7613 8444 7205
New Mexico 5291 6842 7036 7402 7345 7672 7123
Missouri 3213 3235 3137 3373 3383 3421 3565
Ohio na na 8696 8789 9859 11432 9300
Wisconsin 2724 2661 3031 3291 4255 4633 5064
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
15 to 24
25 to 34
35 to 54
55 and up
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Male -140 7355 827 901 1286 -927 742 -758 1157 1241 1306 -829 146 301 1082 1242 1306 -1249
Female 841 5151 103 733 1257 -1521 659 -922 533 1204 1494 -1014 -132 1299 229 1331 1617 -1214
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 4888 4820 8365 9057 9873 11142 10110
Female 3201 3470 5257 5312 5701 6418 5442
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 3611 3879 3585 40 4496 5083 4662
Female 159 1695 1538 162 1816 2087 1875
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 2295 2328 2399 2658 2988 3379 2957
Female 839 828 936 957 1085 126 1107
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017 q1 q2 q3
All drug 3948 4061 6589 6894 7458 8430 7696 889150252325 1075831326045 167997701832
Heroin 1452 1472 1571 1681 1891 2173 191 302341597796 476222826087 215786123488
Opioid 2447 2636 2429 2636 2956 3382 3088 208009807928 283004552352 271305063812
Q12016-Q12017 Q22016-Q22017 Q32016-Q32017
All drug 889150252325 1075831326045 167997701832
Heroin 302341597796 476222826087 215786123488
Opioid 208009807928 283004552352 271305063812
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Heroin 136 674 701 1251 1486 -1209
Opioid 77 -785 853 1212 1442 -868
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Heroin 1452 1472 1571 1681 1891 2173 191
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Heroin 1452 1472 1571 1681 1891 2173 191
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Opioid 77 -785 853 1212 1442 -868
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Heroin 136 674 701 1251 1486 -1209
Q12016-Q12017 Q12016-Q12017 Q12016-Q12017
Q22016-Q22017 Q22016-Q22017 Q22016-Q22017
Q32016-Q32017 Q32016-Q32017 Q32016-Q32017
Page 40: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

table with overall

table with overall

All drug
Suspected all drug overdose rates by 10000 ED visits

Sheet1

All drug

table by sex

Opioid
Quarter year
Suspected opioid overdose rates by 10000 ED visits

table by age

Opioid

table by state

Heroin
Quarter year
Suspected opioid overdose rates by 10000 ED visits
Heroin
All drug
Heroin
Opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Summary

Stable increases for all drug and heroin from Q1 2016 to Q3 2017- Opioid had stable increases from Q3 2016 to Q2 2017

Moderate decreases from Q2 to Q3 2017- 9 for all drug 9 for opioid and 12 for heroin

Annual percentage changes were above 15 increases- Q1 to Q1 89 all drug 30 heroin amp 21 opioid- Q2 to Q2 108 all drug 48 heroin amp 28 opioid- Q3 to Q3 17 all drug 22 heroin amp 27 opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency department data dissemination efforts

ldquoOpioid Overdoses Treated in Emergency Departmentsrdquo -httpswwwcdcgovvitalsignsopioid-overdosesindexhtml

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose

Reporting System

Presenter Julie OrsquoDonnell PhD MPHEpidemiologist

Centers for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Alana Vivolo-Kantor R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Julie OrsquoDonnell PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Increase in deaths outpaces increase in use

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid

overdose

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid overdose surveillance

Track specific substances contributing to overdose deaths

Detect newly-emerging substances involved in overdose

Determine risk factors circumstances associated with fatal overdose

Assess common drug combinations Provide more timely data on overdose deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

State Unintentional Drug Overdose Reporting System (SUDORS)

Death certificates

Medical examiner

coroner reportsToxicology

reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data submitted bi-annually

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

1 Data entry started

2 Data entry finished

1 Data entry started

2 Data entry finished

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS leverages National Violent Death Reporting System (NVDRS) platform

- Basic descriptors- Compare across demographics

- Recent release from institution- Overdose location - Survival time

- Mental health diagnoses- Substance abuse treatment history

- Substances present- Substances contributing to death

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Maine 1941 -1273 225 278 1523 -201 3951 -692 257 -813 2945 981 793 656 -299 -2255 3199 2197
Massachusetts na na na na na na 1561 -157 -848 -1148 311 1897 553 -31 -13 -1632 456 2146
New Hampshire 511 1514 -1438 -832 2583 -961 318 64 -433 -1791 2967 -876 825 -184 -1002 -2016 3363 -17
Pennsylvania na na 869 -102 1211 -116 na na 2979 1751 2589 -594 na na 2601 1534 2735 -735
Rhode Island na na 735 -790 1002 -1594 na na 28 454 544 -1191 na na 121 1057 566 -3262
West Virginia -1596 875 2978 -1543 409 -1651 -367 995 4331 -1664 402 -2377 -769 1847 4571 -1584 -199 -3022
Kentucky -102 1242 -1707 2211 1092 -1468 1095 5192 -2694 4045 352 -2002 -043 5541 -3206 5012 -408 -1624
New Mexico 2932 283 521 -078 445 -716 255 -1298 2611 151 -501 -1093 -487 -3061 3227 987 -1715 323
Missouri 068 -304 754 028 114 421 292 827 477 -177 954 767 -046 1839 096 -512 966 125
Ohio na na 107 1216 1596 -1865 na na 2274 2567 2167 -3194 na na 2182 2254 2086 -3348
Wisconsin -229 1388 861 2928 888 931 -948 986 1712 6728 322 314 -1457 91 983 9621 196 668
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 1514 2112 1966 2017 1853 2398 2634
Massachusetts 7036 8133 8006 7327 6486 6687 7956
New Hampshire 3806 3927 4179 3998 3282 4255 3882
Pennsylvania na na 1265 1641 1929 2428 2284
Rhode Island na na 1498 154 161 1698 1496
West Virginia 2258 2176 2392 3428 2857 2972 2266
Kentucky 2095 2325 3532 258 3624 3752 3001
New Mexico 1927 1976 1719 2168 2201 2091 1862
Missouri 1472 1515 1641 1719 1688 185 1991
Ohio na na 236 2897 3641 443 3015
Wisconsin 664 601 66 773 1294 1336 1377
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 502 9 959 931 721 952 1161
Massachusetts 4035 4258 4126 359 3004 3141 3815
New Hampshire 2514 2721 2671 2403 1919 2564 2128
Pennsylvania na na 1013 1277 1473 1876 1738
Rhode Island na na 803 812 898 949 639
West Virginia 1496 1381 1636 2384 2006 1966 1372
Kentucky 1772 1764 2741 1863 2796 2682 2247
New Mexico 902 858 595 787 865 717 74
Missouri 1002 997 118 1192 1131 124 1255
Ohio na na 1804 2198 2693 3254 2165
Wisconsin 286 244 267 293 575 586 625
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 5609 6697 5845 5976 6142 7078 6936
Massachusetts na na na na na na na
New Hampshire 5678 5968 6872 5883 5394 6787 6135
Pennsylvania na na 8374 9102 9010 10100 9983
Rhode Island na na 3567 3829 3527 3880 3262
West Virginia 4628 3889 4229 5489 4642 4832 4034
Kentucky 6756 6687 7517 6234 7613 8444 7205
New Mexico 5291 6842 7036 7402 7345 7672 7123
Missouri 3213 3235 3137 3373 3383 3421 3565
Ohio na na 8696 8789 9859 11432 9300
Wisconsin 2724 2661 3031 3291 4255 4633 5064
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
15 to 24
25 to 34
35 to 54
55 and up
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Male -140 7355 827 901 1286 -927 742 -758 1157 1241 1306 -829 146 301 1082 1242 1306 -1249
Female 841 5151 103 733 1257 -1521 659 -922 533 1204 1494 -1014 -132 1299 229 1331 1617 -1214
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 4888 4820 8365 9057 9873 11142 10110
Female 3201 3470 5257 5312 5701 6418 5442
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 3611 3879 3585 40 4496 5083 4662
Female 159 1695 1538 162 1816 2087 1875
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 2295 2328 2399 2658 2988 3379 2957
Female 839 828 936 957 1085 126 1107
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017 q1 q2 q3
All drug 3948 4061 6589 6894 7458 8430 7696 889150252325 1075831326045 167997701832
Heroin 1452 1472 1571 1681 1891 2173 191 302341597796 476222826087 215786123488
Opioid 2447 2636 2429 2636 2956 3382 3088 208009807928 283004552352 271305063812
Q12016-Q12017 Q22016-Q22017 Q32016-Q32017
All drug 889150252325 1075831326045 167997701832
Heroin 302341597796 476222826087 215786123488
Opioid 208009807928 283004552352 271305063812
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Heroin 136 674 701 1251 1486 -1209
Opioid 77 -785 853 1212 1442 -868
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Heroin 1452 1472 1571 1681 1891 2173 191
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
All drug 3948 4061 6589 6894 7458 8430 7696
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Opioid 2447 2636 2429 2636 2956 3382 3088
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017
Heroin 1452 1472 1571 1681 1891 2173 191
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
All drug 286 6225 462 819 1303 -871
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Opioid 77 -785 853 1212 1442 -868
Δ fromQ1-Q2 2016 Δ fromQ2-Q3 2016 Δ fromQ3-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1-Q2 2017 Δ fromQ2-Q3 2017
Heroin 136 674 701 1251 1486 -1209
Page 41: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

table with overall

All drug
Suspected all drug overdose rates by 10000 ED visits

Sheet1

All drug

table by sex

Opioid
Quarter year
Suspected opioid overdose rates by 10000 ED visits

table by age

Opioid

table by state

Heroin
Quarter year
Suspected opioid overdose rates by 10000 ED visits
Heroin
All drug
Heroin
Opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Summary

Stable increases for all drug and heroin from Q1 2016 to Q3 2017- Opioid had stable increases from Q3 2016 to Q2 2017

Moderate decreases from Q2 to Q3 2017- 9 for all drug 9 for opioid and 12 for heroin

Annual percentage changes were above 15 increases- Q1 to Q1 89 all drug 30 heroin amp 21 opioid- Q2 to Q2 108 all drug 48 heroin amp 28 opioid- Q3 to Q3 17 all drug 22 heroin amp 27 opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency department data dissemination efforts

ldquoOpioid Overdoses Treated in Emergency Departmentsrdquo -httpswwwcdcgovvitalsignsopioid-overdosesindexhtml

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose

Reporting System

Presenter Julie OrsquoDonnell PhD MPHEpidemiologist

Centers for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Alana Vivolo-Kantor R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Julie OrsquoDonnell PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Increase in deaths outpaces increase in use

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid

overdose

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid overdose surveillance

Track specific substances contributing to overdose deaths

Detect newly-emerging substances involved in overdose

Determine risk factors circumstances associated with fatal overdose

Assess common drug combinations Provide more timely data on overdose deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

State Unintentional Drug Overdose Reporting System (SUDORS)

Death certificates

Medical examiner

coroner reportsToxicology

reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data submitted bi-annually

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

1 Data entry started

2 Data entry finished

1 Data entry started

2 Data entry finished

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS leverages National Violent Death Reporting System (NVDRS) platform

- Basic descriptors- Compare across demographics

- Recent release from institution- Overdose location - Survival time

- Mental health diagnoses- Substance abuse treatment history

- Substances present- Substances contributing to death

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Maine 1941 -1273 225 278 1523 -201 3951 -692 257 -813 2945 981 793 656 -299 -2255 3199 2197
Massachusetts na na na na na na 1561 -157 -848 -1148 311 1897 553 -31 -13 -1632 456 2146
New Hampshire 511 1514 -1438 -832 2583 -961 318 64 -433 -1791 2967 -876 825 -184 -1002 -2016 3363 -17
Pennsylvania na na 869 -102 1211 -116 na na 2979 1751 2589 -594 na na 2601 1534 2735 -735
Rhode Island na na 735 -790 1002 -1594 na na 28 454 544 -1191 na na 121 1057 566 -3262
West Virginia -1596 875 2978 -1543 409 -1651 -367 995 4331 -1664 402 -2377 -769 1847 4571 -1584 -199 -3022
Kentucky -102 1242 -1707 2211 1092 -1468 1095 5192 -2694 4045 352 -2002 -043 5541 -3206 5012 -408 -1624
New Mexico 2932 283 521 -078 445 -716 255 -1298 2611 151 -501 -1093 -487 -3061 3227 987 -1715 323
Missouri 068 -304 754 028 114 421 292 827 477 -177 954 767 -046 1839 096 -512 966 125
Ohio na na 107 1216 1596 -1865 na na 2274 2567 2167 -3194 na na 2182 2254 2086 -3348
Wisconsin -229 1388 861 2928 888 931 -948 986 1712 6728 322 314 -1457 91 983 9621 196 668
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 1514 2112 1966 2017 1853 2398 2634
Massachusetts 7036 8133 8006 7327 6486 6687 7956
New Hampshire 3806 3927 4179 3998 3282 4255 3882
Pennsylvania na na 1265 1641 1929 2428 2284
Rhode Island na na 1498 154 161 1698 1496
West Virginia 2258 2176 2392 3428 2857 2972 2266
Kentucky 2095 2325 3532 258 3624 3752 3001
New Mexico 1927 1976 1719 2168 2201 2091 1862
Missouri 1472 1515 1641 1719 1688 185 1991
Ohio na na 236 2897 3641 443 3015
Wisconsin 664 601 66 773 1294 1336 1377
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 502 9 959 931 721 952 1161
Massachusetts 4035 4258 4126 359 3004 3141 3815
New Hampshire 2514 2721 2671 2403 1919 2564 2128
Pennsylvania na na 1013 1277 1473 1876 1738
Rhode Island na na 803 812 898 949 639
West Virginia 1496 1381 1636 2384 2006 1966 1372
Kentucky 1772 1764 2741 1863 2796 2682 2247
New Mexico 902 858 595 787 865 717 74
Missouri 1002 997 118 1192 1131 124 1255
Ohio na na 1804 2198 2693 3254 2165
Wisconsin 286 244 267 293 575 586 625
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 5609 6697 5845 5976 6142 7078 6936
Massachusetts na na na na na na na
New Hampshire 5678 5968 6872 5883 5394 6787 6135
Pennsylvania na na 8374 9102 9010 10100 9983
Rhode Island na na 3567 3829 3527 3880 3262
West Virginia 4628 3889 4229 5489 4642 4832 4034
Kentucky 6756 6687 7517 6234 7613 8444 7205
New Mexico 5291 6842 7036 7402 7345 7672 7123
Missouri 3213 3235 3137 3373 3383 3421 3565
Ohio na na 8696 8789 9859 11432 9300
Wisconsin 2724 2661 3031 3291 4255 4633 5064
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
15 to 24
25 to 34
35 to 54
55 and up
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Male -140 7355 827 901 1286 -927 742 -758 1157 1241 1306 -829 146 301 1082 1242 1306 -1249
Female 841 5151 103 733 1257 -1521 659 -922 533 1204 1494 -1014 -132 1299 229 1331 1617 -1214
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 4888 4820 8365 9057 9873 11142 10110
Female 3201 3470 5257 5312 5701 6418 5442
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 3611 3879 3585 40 4496 5083 4662
Female 159 1695 1538 162 1816 2087 1875
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 2295 2328 2399 2658 2988 3379 2957
Female 839 828 936 957 1085 126 1107
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017 q1 q2 q3
All drug 3948 4061 6589 6894 7458 8430 7696 889150252325 1075831326045 167997701832
Heroin 1452 1472 1571 1681 1891 2173 191 302341597796 476222826087 215786123488
Opioid 2447 2636 2429 2636 2956 3382 3088 208009807928 283004552352 271305063812
Q12016-Q12017 Q22016-Q22017 Q32016-Q32017
All drug 889150252325 1075831326045 167997701832
Heroin 302341597796 476222826087 215786123488
Opioid 208009807928 283004552352 271305063812
Page 42: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Sheet1

All drug

table by sex

Opioid
Quarter year
Suspected opioid overdose rates by 10000 ED visits

table by age

Opioid

table by state

Heroin
Quarter year
Suspected opioid overdose rates by 10000 ED visits
Heroin
All drug
Heroin
Opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Summary

Stable increases for all drug and heroin from Q1 2016 to Q3 2017- Opioid had stable increases from Q3 2016 to Q2 2017

Moderate decreases from Q2 to Q3 2017- 9 for all drug 9 for opioid and 12 for heroin

Annual percentage changes were above 15 increases- Q1 to Q1 89 all drug 30 heroin amp 21 opioid- Q2 to Q2 108 all drug 48 heroin amp 28 opioid- Q3 to Q3 17 all drug 22 heroin amp 27 opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency department data dissemination efforts

ldquoOpioid Overdoses Treated in Emergency Departmentsrdquo -httpswwwcdcgovvitalsignsopioid-overdosesindexhtml

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose

Reporting System

Presenter Julie OrsquoDonnell PhD MPHEpidemiologist

Centers for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Alana Vivolo-Kantor R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Julie OrsquoDonnell PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Increase in deaths outpaces increase in use

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid

overdose

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid overdose surveillance

Track specific substances contributing to overdose deaths

Detect newly-emerging substances involved in overdose

Determine risk factors circumstances associated with fatal overdose

Assess common drug combinations Provide more timely data on overdose deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

State Unintentional Drug Overdose Reporting System (SUDORS)

Death certificates

Medical examiner

coroner reportsToxicology

reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data submitted bi-annually

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

1 Data entry started

2 Data entry finished

1 Data entry started

2 Data entry finished

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS leverages National Violent Death Reporting System (NVDRS) platform

- Basic descriptors- Compare across demographics

- Recent release from institution- Overdose location - Survival time

- Mental health diagnoses- Substance abuse treatment history

- Substances present- Substances contributing to death

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Maine 1941 -1273 225 278 1523 -201 3951 -692 257 -813 2945 981 793 656 -299 -2255 3199 2197
Massachusetts na na na na na na 1561 -157 -848 -1148 311 1897 553 -31 -13 -1632 456 2146
New Hampshire 511 1514 -1438 -832 2583 -961 318 64 -433 -1791 2967 -876 825 -184 -1002 -2016 3363 -17
Pennsylvania na na 869 -102 1211 -116 na na 2979 1751 2589 -594 na na 2601 1534 2735 -735
Rhode Island na na 735 -790 1002 -1594 na na 28 454 544 -1191 na na 121 1057 566 -3262
West Virginia -1596 875 2978 -1543 409 -1651 -367 995 4331 -1664 402 -2377 -769 1847 4571 -1584 -199 -3022
Kentucky -102 1242 -1707 2211 1092 -1468 1095 5192 -2694 4045 352 -2002 -043 5541 -3206 5012 -408 -1624
New Mexico 2932 283 521 -078 445 -716 255 -1298 2611 151 -501 -1093 -487 -3061 3227 987 -1715 323
Missouri 068 -304 754 028 114 421 292 827 477 -177 954 767 -046 1839 096 -512 966 125
Ohio na na 107 1216 1596 -1865 na na 2274 2567 2167 -3194 na na 2182 2254 2086 -3348
Wisconsin -229 1388 861 2928 888 931 -948 986 1712 6728 322 314 -1457 91 983 9621 196 668
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 1514 2112 1966 2017 1853 2398 2634
Massachusetts 7036 8133 8006 7327 6486 6687 7956
New Hampshire 3806 3927 4179 3998 3282 4255 3882
Pennsylvania na na 1265 1641 1929 2428 2284
Rhode Island na na 1498 154 161 1698 1496
West Virginia 2258 2176 2392 3428 2857 2972 2266
Kentucky 2095 2325 3532 258 3624 3752 3001
New Mexico 1927 1976 1719 2168 2201 2091 1862
Missouri 1472 1515 1641 1719 1688 185 1991
Ohio na na 236 2897 3641 443 3015
Wisconsin 664 601 66 773 1294 1336 1377
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 502 9 959 931 721 952 1161
Massachusetts 4035 4258 4126 359 3004 3141 3815
New Hampshire 2514 2721 2671 2403 1919 2564 2128
Pennsylvania na na 1013 1277 1473 1876 1738
Rhode Island na na 803 812 898 949 639
West Virginia 1496 1381 1636 2384 2006 1966 1372
Kentucky 1772 1764 2741 1863 2796 2682 2247
New Mexico 902 858 595 787 865 717 74
Missouri 1002 997 118 1192 1131 124 1255
Ohio na na 1804 2198 2693 3254 2165
Wisconsin 286 244 267 293 575 586 625
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 5609 6697 5845 5976 6142 7078 6936
Massachusetts na na na na na na na
New Hampshire 5678 5968 6872 5883 5394 6787 6135
Pennsylvania na na 8374 9102 9010 10100 9983
Rhode Island na na 3567 3829 3527 3880 3262
West Virginia 4628 3889 4229 5489 4642 4832 4034
Kentucky 6756 6687 7517 6234 7613 8444 7205
New Mexico 5291 6842 7036 7402 7345 7672 7123
Missouri 3213 3235 3137 3373 3383 3421 3565
Ohio na na 8696 8789 9859 11432 9300
Wisconsin 2724 2661 3031 3291 4255 4633 5064
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
15 to 24
25 to 34
35 to 54
55 and up
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Male -140 7355 827 901 1286 -927 742 -758 1157 1241 1306 -829 146 301 1082 1242 1306 -1249
Female 841 5151 103 733 1257 -1521 659 -922 533 1204 1494 -1014 -132 1299 229 1331 1617 -1214
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 4888 4820 8365 9057 9873 11142 10110
Female 3201 3470 5257 5312 5701 6418 5442
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 3611 3879 3585 40 4496 5083 4662
Female 159 1695 1538 162 1816 2087 1875
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 2295 2328 2399 2658 2988 3379 2957
Female 839 828 936 957 1085 126 1107
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017 q1 q2 q3
All drug 3948 4061 6589 6894 7458 8430 7696 889150252325 1075831326045 167997701832
Heroin 1452 1472 1571 1681 1891 2173 191 302341597796 476222826087 215786123488
Opioid 2447 2636 2429 2636 2956 3382 3088 208009807928 283004552352 271305063812
Q12016-Q12017 Q22016-Q22017 Q32016-Q32017
All drug 889150252325 1075831326045 167997701832
Heroin 302341597796 476222826087 215786123488
Opioid 208009807928 283004552352 271305063812
Page 43: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

table by sex

Opioid
Quarter year
Suspected opioid overdose rates by 10000 ED visits

table by age

Opioid

table by state

Heroin
Quarter year
Suspected opioid overdose rates by 10000 ED visits
Heroin
All drug
Heroin
Opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Summary

Stable increases for all drug and heroin from Q1 2016 to Q3 2017- Opioid had stable increases from Q3 2016 to Q2 2017

Moderate decreases from Q2 to Q3 2017- 9 for all drug 9 for opioid and 12 for heroin

Annual percentage changes were above 15 increases- Q1 to Q1 89 all drug 30 heroin amp 21 opioid- Q2 to Q2 108 all drug 48 heroin amp 28 opioid- Q3 to Q3 17 all drug 22 heroin amp 27 opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency department data dissemination efforts

ldquoOpioid Overdoses Treated in Emergency Departmentsrdquo -httpswwwcdcgovvitalsignsopioid-overdosesindexhtml

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose

Reporting System

Presenter Julie OrsquoDonnell PhD MPHEpidemiologist

Centers for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Alana Vivolo-Kantor R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Julie OrsquoDonnell PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Increase in deaths outpaces increase in use

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid

overdose

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid overdose surveillance

Track specific substances contributing to overdose deaths

Detect newly-emerging substances involved in overdose

Determine risk factors circumstances associated with fatal overdose

Assess common drug combinations Provide more timely data on overdose deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

State Unintentional Drug Overdose Reporting System (SUDORS)

Death certificates

Medical examiner

coroner reportsToxicology

reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data submitted bi-annually

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

1 Data entry started

2 Data entry finished

1 Data entry started

2 Data entry finished

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS leverages National Violent Death Reporting System (NVDRS) platform

- Basic descriptors- Compare across demographics

- Recent release from institution- Overdose location - Survival time

- Mental health diagnoses- Substance abuse treatment history

- Substances present- Substances contributing to death

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Maine 1941 -1273 225 278 1523 -201 3951 -692 257 -813 2945 981 793 656 -299 -2255 3199 2197
Massachusetts na na na na na na 1561 -157 -848 -1148 311 1897 553 -31 -13 -1632 456 2146
New Hampshire 511 1514 -1438 -832 2583 -961 318 64 -433 -1791 2967 -876 825 -184 -1002 -2016 3363 -17
Pennsylvania na na 869 -102 1211 -116 na na 2979 1751 2589 -594 na na 2601 1534 2735 -735
Rhode Island na na 735 -790 1002 -1594 na na 28 454 544 -1191 na na 121 1057 566 -3262
West Virginia -1596 875 2978 -1543 409 -1651 -367 995 4331 -1664 402 -2377 -769 1847 4571 -1584 -199 -3022
Kentucky -102 1242 -1707 2211 1092 -1468 1095 5192 -2694 4045 352 -2002 -043 5541 -3206 5012 -408 -1624
New Mexico 2932 283 521 -078 445 -716 255 -1298 2611 151 -501 -1093 -487 -3061 3227 987 -1715 323
Missouri 068 -304 754 028 114 421 292 827 477 -177 954 767 -046 1839 096 -512 966 125
Ohio na na 107 1216 1596 -1865 na na 2274 2567 2167 -3194 na na 2182 2254 2086 -3348
Wisconsin -229 1388 861 2928 888 931 -948 986 1712 6728 322 314 -1457 91 983 9621 196 668
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 1514 2112 1966 2017 1853 2398 2634
Massachusetts 7036 8133 8006 7327 6486 6687 7956
New Hampshire 3806 3927 4179 3998 3282 4255 3882
Pennsylvania na na 1265 1641 1929 2428 2284
Rhode Island na na 1498 154 161 1698 1496
West Virginia 2258 2176 2392 3428 2857 2972 2266
Kentucky 2095 2325 3532 258 3624 3752 3001
New Mexico 1927 1976 1719 2168 2201 2091 1862
Missouri 1472 1515 1641 1719 1688 185 1991
Ohio na na 236 2897 3641 443 3015
Wisconsin 664 601 66 773 1294 1336 1377
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 502 9 959 931 721 952 1161
Massachusetts 4035 4258 4126 359 3004 3141 3815
New Hampshire 2514 2721 2671 2403 1919 2564 2128
Pennsylvania na na 1013 1277 1473 1876 1738
Rhode Island na na 803 812 898 949 639
West Virginia 1496 1381 1636 2384 2006 1966 1372
Kentucky 1772 1764 2741 1863 2796 2682 2247
New Mexico 902 858 595 787 865 717 74
Missouri 1002 997 118 1192 1131 124 1255
Ohio na na 1804 2198 2693 3254 2165
Wisconsin 286 244 267 293 575 586 625
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 5609 6697 5845 5976 6142 7078 6936
Massachusetts na na na na na na na
New Hampshire 5678 5968 6872 5883 5394 6787 6135
Pennsylvania na na 8374 9102 9010 10100 9983
Rhode Island na na 3567 3829 3527 3880 3262
West Virginia 4628 3889 4229 5489 4642 4832 4034
Kentucky 6756 6687 7517 6234 7613 8444 7205
New Mexico 5291 6842 7036 7402 7345 7672 7123
Missouri 3213 3235 3137 3373 3383 3421 3565
Ohio na na 8696 8789 9859 11432 9300
Wisconsin 2724 2661 3031 3291 4255 4633 5064
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
15 to 24
25 to 34
35 to 54
55 and up
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Male -140 7355 827 901 1286 -927 742 -758 1157 1241 1306 -829 146 301 1082 1242 1306 -1249
Female 841 5151 103 733 1257 -1521 659 -922 533 1204 1494 -1014 -132 1299 229 1331 1617 -1214
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 4888 4820 8365 9057 9873 11142 10110
Female 3201 3470 5257 5312 5701 6418 5442
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 3611 3879 3585 40 4496 5083 4662
Female 159 1695 1538 162 1816 2087 1875
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 2295 2328 2399 2658 2988 3379 2957
Female 839 828 936 957 1085 126 1107
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017 q1 q2 q3
All drug 3948 4061 6589 6894 7458 8430 7696 889150252325 1075831326045 167997701832
Heroin 1452 1472 1571 1681 1891 2173 191 302341597796 476222826087 215786123488
Opioid 2447 2636 2429 2636 2956 3382 3088 208009807928 283004552352 271305063812
Q12016-Q12017 Q22016-Q22017 Q32016-Q32017
All drug 889150252325 1075831326045 167997701832
Heroin 302341597796 476222826087 215786123488
Opioid 208009807928 283004552352 271305063812
Page 44: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

table by age

Opioid

table by state

Heroin
Quarter year
Suspected opioid overdose rates by 10000 ED visits
Heroin
All drug
Heroin
Opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Summary

Stable increases for all drug and heroin from Q1 2016 to Q3 2017- Opioid had stable increases from Q3 2016 to Q2 2017

Moderate decreases from Q2 to Q3 2017- 9 for all drug 9 for opioid and 12 for heroin

Annual percentage changes were above 15 increases- Q1 to Q1 89 all drug 30 heroin amp 21 opioid- Q2 to Q2 108 all drug 48 heroin amp 28 opioid- Q3 to Q3 17 all drug 22 heroin amp 27 opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency department data dissemination efforts

ldquoOpioid Overdoses Treated in Emergency Departmentsrdquo -httpswwwcdcgovvitalsignsopioid-overdosesindexhtml

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose

Reporting System

Presenter Julie OrsquoDonnell PhD MPHEpidemiologist

Centers for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Alana Vivolo-Kantor R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Julie OrsquoDonnell PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Increase in deaths outpaces increase in use

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid

overdose

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid overdose surveillance

Track specific substances contributing to overdose deaths

Detect newly-emerging substances involved in overdose

Determine risk factors circumstances associated with fatal overdose

Assess common drug combinations Provide more timely data on overdose deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

State Unintentional Drug Overdose Reporting System (SUDORS)

Death certificates

Medical examiner

coroner reportsToxicology

reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data submitted bi-annually

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

1 Data entry started

2 Data entry finished

1 Data entry started

2 Data entry finished

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS leverages National Violent Death Reporting System (NVDRS) platform

- Basic descriptors- Compare across demographics

- Recent release from institution- Overdose location - Survival time

- Mental health diagnoses- Substance abuse treatment history

- Substances present- Substances contributing to death

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Maine 1941 -1273 225 278 1523 -201 3951 -692 257 -813 2945 981 793 656 -299 -2255 3199 2197
Massachusetts na na na na na na 1561 -157 -848 -1148 311 1897 553 -31 -13 -1632 456 2146
New Hampshire 511 1514 -1438 -832 2583 -961 318 64 -433 -1791 2967 -876 825 -184 -1002 -2016 3363 -17
Pennsylvania na na 869 -102 1211 -116 na na 2979 1751 2589 -594 na na 2601 1534 2735 -735
Rhode Island na na 735 -790 1002 -1594 na na 28 454 544 -1191 na na 121 1057 566 -3262
West Virginia -1596 875 2978 -1543 409 -1651 -367 995 4331 -1664 402 -2377 -769 1847 4571 -1584 -199 -3022
Kentucky -102 1242 -1707 2211 1092 -1468 1095 5192 -2694 4045 352 -2002 -043 5541 -3206 5012 -408 -1624
New Mexico 2932 283 521 -078 445 -716 255 -1298 2611 151 -501 -1093 -487 -3061 3227 987 -1715 323
Missouri 068 -304 754 028 114 421 292 827 477 -177 954 767 -046 1839 096 -512 966 125
Ohio na na 107 1216 1596 -1865 na na 2274 2567 2167 -3194 na na 2182 2254 2086 -3348
Wisconsin -229 1388 861 2928 888 931 -948 986 1712 6728 322 314 -1457 91 983 9621 196 668
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 1514 2112 1966 2017 1853 2398 2634
Massachusetts 7036 8133 8006 7327 6486 6687 7956
New Hampshire 3806 3927 4179 3998 3282 4255 3882
Pennsylvania na na 1265 1641 1929 2428 2284
Rhode Island na na 1498 154 161 1698 1496
West Virginia 2258 2176 2392 3428 2857 2972 2266
Kentucky 2095 2325 3532 258 3624 3752 3001
New Mexico 1927 1976 1719 2168 2201 2091 1862
Missouri 1472 1515 1641 1719 1688 185 1991
Ohio na na 236 2897 3641 443 3015
Wisconsin 664 601 66 773 1294 1336 1377
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 502 9 959 931 721 952 1161
Massachusetts 4035 4258 4126 359 3004 3141 3815
New Hampshire 2514 2721 2671 2403 1919 2564 2128
Pennsylvania na na 1013 1277 1473 1876 1738
Rhode Island na na 803 812 898 949 639
West Virginia 1496 1381 1636 2384 2006 1966 1372
Kentucky 1772 1764 2741 1863 2796 2682 2247
New Mexico 902 858 595 787 865 717 74
Missouri 1002 997 118 1192 1131 124 1255
Ohio na na 1804 2198 2693 3254 2165
Wisconsin 286 244 267 293 575 586 625
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 5609 6697 5845 5976 6142 7078 6936
Massachusetts na na na na na na na
New Hampshire 5678 5968 6872 5883 5394 6787 6135
Pennsylvania na na 8374 9102 9010 10100 9983
Rhode Island na na 3567 3829 3527 3880 3262
West Virginia 4628 3889 4229 5489 4642 4832 4034
Kentucky 6756 6687 7517 6234 7613 8444 7205
New Mexico 5291 6842 7036 7402 7345 7672 7123
Missouri 3213 3235 3137 3373 3383 3421 3565
Ohio na na 8696 8789 9859 11432 9300
Wisconsin 2724 2661 3031 3291 4255 4633 5064
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
15 to 24
25 to 34
35 to 54
55 and up
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Male -140 7355 827 901 1286 -927 742 -758 1157 1241 1306 -829 146 301 1082 1242 1306 -1249
Female 841 5151 103 733 1257 -1521 659 -922 533 1204 1494 -1014 -132 1299 229 1331 1617 -1214
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 4888 4820 8365 9057 9873 11142 10110
Female 3201 3470 5257 5312 5701 6418 5442
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 3611 3879 3585 40 4496 5083 4662
Female 159 1695 1538 162 1816 2087 1875
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 2295 2328 2399 2658 2988 3379 2957
Female 839 828 936 957 1085 126 1107
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017 q1 q2 q3
All drug 3948 4061 6589 6894 7458 8430 7696 889150252325 1075831326045 167997701832
Heroin 1452 1472 1571 1681 1891 2173 191 302341597796 476222826087 215786123488
Opioid 2447 2636 2429 2636 2956 3382 3088 208009807928 283004552352 271305063812
Q12016-Q12017 Q22016-Q22017 Q32016-Q32017
All drug 889150252325 1075831326045 167997701832
Heroin 302341597796 476222826087 215786123488
Opioid 208009807928 283004552352 271305063812
Page 45: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

table by state

Heroin
Quarter year
Suspected opioid overdose rates by 10000 ED visits
Heroin
All drug
Heroin
Opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Summary

Stable increases for all drug and heroin from Q1 2016 to Q3 2017- Opioid had stable increases from Q3 2016 to Q2 2017

Moderate decreases from Q2 to Q3 2017- 9 for all drug 9 for opioid and 12 for heroin

Annual percentage changes were above 15 increases- Q1 to Q1 89 all drug 30 heroin amp 21 opioid- Q2 to Q2 108 all drug 48 heroin amp 28 opioid- Q3 to Q3 17 all drug 22 heroin amp 27 opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency department data dissemination efforts

ldquoOpioid Overdoses Treated in Emergency Departmentsrdquo -httpswwwcdcgovvitalsignsopioid-overdosesindexhtml

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose

Reporting System

Presenter Julie OrsquoDonnell PhD MPHEpidemiologist

Centers for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Alana Vivolo-Kantor R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Julie OrsquoDonnell PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Increase in deaths outpaces increase in use

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid

overdose

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid overdose surveillance

Track specific substances contributing to overdose deaths

Detect newly-emerging substances involved in overdose

Determine risk factors circumstances associated with fatal overdose

Assess common drug combinations Provide more timely data on overdose deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

State Unintentional Drug Overdose Reporting System (SUDORS)

Death certificates

Medical examiner

coroner reportsToxicology

reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data submitted bi-annually

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

1 Data entry started

2 Data entry finished

1 Data entry started

2 Data entry finished

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS leverages National Violent Death Reporting System (NVDRS) platform

- Basic descriptors- Compare across demographics

- Recent release from institution- Overdose location - Survival time

- Mental health diagnoses- Substance abuse treatment history

- Substances present- Substances contributing to death

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Maine 1941 -1273 225 278 1523 -201 3951 -692 257 -813 2945 981 793 656 -299 -2255 3199 2197
Massachusetts na na na na na na 1561 -157 -848 -1148 311 1897 553 -31 -13 -1632 456 2146
New Hampshire 511 1514 -1438 -832 2583 -961 318 64 -433 -1791 2967 -876 825 -184 -1002 -2016 3363 -17
Pennsylvania na na 869 -102 1211 -116 na na 2979 1751 2589 -594 na na 2601 1534 2735 -735
Rhode Island na na 735 -790 1002 -1594 na na 28 454 544 -1191 na na 121 1057 566 -3262
West Virginia -1596 875 2978 -1543 409 -1651 -367 995 4331 -1664 402 -2377 -769 1847 4571 -1584 -199 -3022
Kentucky -102 1242 -1707 2211 1092 -1468 1095 5192 -2694 4045 352 -2002 -043 5541 -3206 5012 -408 -1624
New Mexico 2932 283 521 -078 445 -716 255 -1298 2611 151 -501 -1093 -487 -3061 3227 987 -1715 323
Missouri 068 -304 754 028 114 421 292 827 477 -177 954 767 -046 1839 096 -512 966 125
Ohio na na 107 1216 1596 -1865 na na 2274 2567 2167 -3194 na na 2182 2254 2086 -3348
Wisconsin -229 1388 861 2928 888 931 -948 986 1712 6728 322 314 -1457 91 983 9621 196 668
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 1514 2112 1966 2017 1853 2398 2634
Massachusetts 7036 8133 8006 7327 6486 6687 7956
New Hampshire 3806 3927 4179 3998 3282 4255 3882
Pennsylvania na na 1265 1641 1929 2428 2284
Rhode Island na na 1498 154 161 1698 1496
West Virginia 2258 2176 2392 3428 2857 2972 2266
Kentucky 2095 2325 3532 258 3624 3752 3001
New Mexico 1927 1976 1719 2168 2201 2091 1862
Missouri 1472 1515 1641 1719 1688 185 1991
Ohio na na 236 2897 3641 443 3015
Wisconsin 664 601 66 773 1294 1336 1377
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 502 9 959 931 721 952 1161
Massachusetts 4035 4258 4126 359 3004 3141 3815
New Hampshire 2514 2721 2671 2403 1919 2564 2128
Pennsylvania na na 1013 1277 1473 1876 1738
Rhode Island na na 803 812 898 949 639
West Virginia 1496 1381 1636 2384 2006 1966 1372
Kentucky 1772 1764 2741 1863 2796 2682 2247
New Mexico 902 858 595 787 865 717 74
Missouri 1002 997 118 1192 1131 124 1255
Ohio na na 1804 2198 2693 3254 2165
Wisconsin 286 244 267 293 575 586 625
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 5609 6697 5845 5976 6142 7078 6936
Massachusetts na na na na na na na
New Hampshire 5678 5968 6872 5883 5394 6787 6135
Pennsylvania na na 8374 9102 9010 10100 9983
Rhode Island na na 3567 3829 3527 3880 3262
West Virginia 4628 3889 4229 5489 4642 4832 4034
Kentucky 6756 6687 7517 6234 7613 8444 7205
New Mexico 5291 6842 7036 7402 7345 7672 7123
Missouri 3213 3235 3137 3373 3383 3421 3565
Ohio na na 8696 8789 9859 11432 9300
Wisconsin 2724 2661 3031 3291 4255 4633 5064
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
15 to 24
25 to 34
35 to 54
55 and up
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Male -140 7355 827 901 1286 -927 742 -758 1157 1241 1306 -829 146 301 1082 1242 1306 -1249
Female 841 5151 103 733 1257 -1521 659 -922 533 1204 1494 -1014 -132 1299 229 1331 1617 -1214
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 4888 4820 8365 9057 9873 11142 10110
Female 3201 3470 5257 5312 5701 6418 5442
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 3611 3879 3585 40 4496 5083 4662
Female 159 1695 1538 162 1816 2087 1875
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 2295 2328 2399 2658 2988 3379 2957
Female 839 828 936 957 1085 126 1107
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017 q1 q2 q3
All drug 3948 4061 6589 6894 7458 8430 7696 889150252325 1075831326045 167997701832
Heroin 1452 1472 1571 1681 1891 2173 191 302341597796 476222826087 215786123488
Opioid 2447 2636 2429 2636 2956 3382 3088 208009807928 283004552352 271305063812
Q12016-Q12017 Q22016-Q22017 Q32016-Q32017
All drug 889150252325 1075831326045 167997701832
Heroin 302341597796 476222826087 215786123488
Opioid 208009807928 283004552352 271305063812
Page 46: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease
Heroin
All drug
Heroin
Opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Summary

Stable increases for all drug and heroin from Q1 2016 to Q3 2017- Opioid had stable increases from Q3 2016 to Q2 2017

Moderate decreases from Q2 to Q3 2017- 9 for all drug 9 for opioid and 12 for heroin

Annual percentage changes were above 15 increases- Q1 to Q1 89 all drug 30 heroin amp 21 opioid- Q2 to Q2 108 all drug 48 heroin amp 28 opioid- Q3 to Q3 17 all drug 22 heroin amp 27 opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency department data dissemination efforts

ldquoOpioid Overdoses Treated in Emergency Departmentsrdquo -httpswwwcdcgovvitalsignsopioid-overdosesindexhtml

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose

Reporting System

Presenter Julie OrsquoDonnell PhD MPHEpidemiologist

Centers for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Alana Vivolo-Kantor R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Julie OrsquoDonnell PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Increase in deaths outpaces increase in use

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid

overdose

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid overdose surveillance

Track specific substances contributing to overdose deaths

Detect newly-emerging substances involved in overdose

Determine risk factors circumstances associated with fatal overdose

Assess common drug combinations Provide more timely data on overdose deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

State Unintentional Drug Overdose Reporting System (SUDORS)

Death certificates

Medical examiner

coroner reportsToxicology

reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data submitted bi-annually

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

1 Data entry started

2 Data entry finished

1 Data entry started

2 Data entry finished

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS leverages National Violent Death Reporting System (NVDRS) platform

- Basic descriptors- Compare across demographics

- Recent release from institution- Overdose location - Survival time

- Mental health diagnoses- Substance abuse treatment history

- Substances present- Substances contributing to death

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Maine 1941 -1273 225 278 1523 -201 3951 -692 257 -813 2945 981 793 656 -299 -2255 3199 2197
Massachusetts na na na na na na 1561 -157 -848 -1148 311 1897 553 -31 -13 -1632 456 2146
New Hampshire 511 1514 -1438 -832 2583 -961 318 64 -433 -1791 2967 -876 825 -184 -1002 -2016 3363 -17
Pennsylvania na na 869 -102 1211 -116 na na 2979 1751 2589 -594 na na 2601 1534 2735 -735
Rhode Island na na 735 -790 1002 -1594 na na 28 454 544 -1191 na na 121 1057 566 -3262
West Virginia -1596 875 2978 -1543 409 -1651 -367 995 4331 -1664 402 -2377 -769 1847 4571 -1584 -199 -3022
Kentucky -102 1242 -1707 2211 1092 -1468 1095 5192 -2694 4045 352 -2002 -043 5541 -3206 5012 -408 -1624
New Mexico 2932 283 521 -078 445 -716 255 -1298 2611 151 -501 -1093 -487 -3061 3227 987 -1715 323
Missouri 068 -304 754 028 114 421 292 827 477 -177 954 767 -046 1839 096 -512 966 125
Ohio na na 107 1216 1596 -1865 na na 2274 2567 2167 -3194 na na 2182 2254 2086 -3348
Wisconsin -229 1388 861 2928 888 931 -948 986 1712 6728 322 314 -1457 91 983 9621 196 668
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 1514 2112 1966 2017 1853 2398 2634
Massachusetts 7036 8133 8006 7327 6486 6687 7956
New Hampshire 3806 3927 4179 3998 3282 4255 3882
Pennsylvania na na 1265 1641 1929 2428 2284
Rhode Island na na 1498 154 161 1698 1496
West Virginia 2258 2176 2392 3428 2857 2972 2266
Kentucky 2095 2325 3532 258 3624 3752 3001
New Mexico 1927 1976 1719 2168 2201 2091 1862
Missouri 1472 1515 1641 1719 1688 185 1991
Ohio na na 236 2897 3641 443 3015
Wisconsin 664 601 66 773 1294 1336 1377
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 502 9 959 931 721 952 1161
Massachusetts 4035 4258 4126 359 3004 3141 3815
New Hampshire 2514 2721 2671 2403 1919 2564 2128
Pennsylvania na na 1013 1277 1473 1876 1738
Rhode Island na na 803 812 898 949 639
West Virginia 1496 1381 1636 2384 2006 1966 1372
Kentucky 1772 1764 2741 1863 2796 2682 2247
New Mexico 902 858 595 787 865 717 74
Missouri 1002 997 118 1192 1131 124 1255
Ohio na na 1804 2198 2693 3254 2165
Wisconsin 286 244 267 293 575 586 625
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 5609 6697 5845 5976 6142 7078 6936
Massachusetts na na na na na na na
New Hampshire 5678 5968 6872 5883 5394 6787 6135
Pennsylvania na na 8374 9102 9010 10100 9983
Rhode Island na na 3567 3829 3527 3880 3262
West Virginia 4628 3889 4229 5489 4642 4832 4034
Kentucky 6756 6687 7517 6234 7613 8444 7205
New Mexico 5291 6842 7036 7402 7345 7672 7123
Missouri 3213 3235 3137 3373 3383 3421 3565
Ohio na na 8696 8789 9859 11432 9300
Wisconsin 2724 2661 3031 3291 4255 4633 5064
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
15 to 24
25 to 34
35 to 54
55 and up
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Male -140 7355 827 901 1286 -927 742 -758 1157 1241 1306 -829 146 301 1082 1242 1306 -1249
Female 841 5151 103 733 1257 -1521 659 -922 533 1204 1494 -1014 -132 1299 229 1331 1617 -1214
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 4888 4820 8365 9057 9873 11142 10110
Female 3201 3470 5257 5312 5701 6418 5442
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 3611 3879 3585 40 4496 5083 4662
Female 159 1695 1538 162 1816 2087 1875
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 2295 2328 2399 2658 2988 3379 2957
Female 839 828 936 957 1085 126 1107
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017 q1 q2 q3
All drug 3948 4061 6589 6894 7458 8430 7696 889150252325 1075831326045 167997701832
Heroin 1452 1472 1571 1681 1891 2173 191 302341597796 476222826087 215786123488
Opioid 2447 2636 2429 2636 2956 3382 3088 208009807928 283004552352 271305063812
Q12016-Q12017 Q22016-Q22017 Q32016-Q32017
All drug 889150252325 1075831326045 167997701832
Heroin 302341597796 476222826087 215786123488
Opioid 208009807928 283004552352 271305063812
Page 47: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease
All drug
Heroin
Opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Summary

Stable increases for all drug and heroin from Q1 2016 to Q3 2017- Opioid had stable increases from Q3 2016 to Q2 2017

Moderate decreases from Q2 to Q3 2017- 9 for all drug 9 for opioid and 12 for heroin

Annual percentage changes were above 15 increases- Q1 to Q1 89 all drug 30 heroin amp 21 opioid- Q2 to Q2 108 all drug 48 heroin amp 28 opioid- Q3 to Q3 17 all drug 22 heroin amp 27 opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency department data dissemination efforts

ldquoOpioid Overdoses Treated in Emergency Departmentsrdquo -httpswwwcdcgovvitalsignsopioid-overdosesindexhtml

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose

Reporting System

Presenter Julie OrsquoDonnell PhD MPHEpidemiologist

Centers for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Alana Vivolo-Kantor R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Julie OrsquoDonnell PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Increase in deaths outpaces increase in use

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid

overdose

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid overdose surveillance

Track specific substances contributing to overdose deaths

Detect newly-emerging substances involved in overdose

Determine risk factors circumstances associated with fatal overdose

Assess common drug combinations Provide more timely data on overdose deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

State Unintentional Drug Overdose Reporting System (SUDORS)

Death certificates

Medical examiner

coroner reportsToxicology

reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data submitted bi-annually

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

1 Data entry started

2 Data entry finished

1 Data entry started

2 Data entry finished

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS leverages National Violent Death Reporting System (NVDRS) platform

- Basic descriptors- Compare across demographics

- Recent release from institution- Overdose location - Survival time

- Mental health diagnoses- Substance abuse treatment history

- Substances present- Substances contributing to death

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Maine 1941 -1273 225 278 1523 -201 3951 -692 257 -813 2945 981 793 656 -299 -2255 3199 2197
Massachusetts na na na na na na 1561 -157 -848 -1148 311 1897 553 -31 -13 -1632 456 2146
New Hampshire 511 1514 -1438 -832 2583 -961 318 64 -433 -1791 2967 -876 825 -184 -1002 -2016 3363 -17
Pennsylvania na na 869 -102 1211 -116 na na 2979 1751 2589 -594 na na 2601 1534 2735 -735
Rhode Island na na 735 -790 1002 -1594 na na 28 454 544 -1191 na na 121 1057 566 -3262
West Virginia -1596 875 2978 -1543 409 -1651 -367 995 4331 -1664 402 -2377 -769 1847 4571 -1584 -199 -3022
Kentucky -102 1242 -1707 2211 1092 -1468 1095 5192 -2694 4045 352 -2002 -043 5541 -3206 5012 -408 -1624
New Mexico 2932 283 521 -078 445 -716 255 -1298 2611 151 -501 -1093 -487 -3061 3227 987 -1715 323
Missouri 068 -304 754 028 114 421 292 827 477 -177 954 767 -046 1839 096 -512 966 125
Ohio na na 107 1216 1596 -1865 na na 2274 2567 2167 -3194 na na 2182 2254 2086 -3348
Wisconsin -229 1388 861 2928 888 931 -948 986 1712 6728 322 314 -1457 91 983 9621 196 668
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 1514 2112 1966 2017 1853 2398 2634
Massachusetts 7036 8133 8006 7327 6486 6687 7956
New Hampshire 3806 3927 4179 3998 3282 4255 3882
Pennsylvania na na 1265 1641 1929 2428 2284
Rhode Island na na 1498 154 161 1698 1496
West Virginia 2258 2176 2392 3428 2857 2972 2266
Kentucky 2095 2325 3532 258 3624 3752 3001
New Mexico 1927 1976 1719 2168 2201 2091 1862
Missouri 1472 1515 1641 1719 1688 185 1991
Ohio na na 236 2897 3641 443 3015
Wisconsin 664 601 66 773 1294 1336 1377
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 502 9 959 931 721 952 1161
Massachusetts 4035 4258 4126 359 3004 3141 3815
New Hampshire 2514 2721 2671 2403 1919 2564 2128
Pennsylvania na na 1013 1277 1473 1876 1738
Rhode Island na na 803 812 898 949 639
West Virginia 1496 1381 1636 2384 2006 1966 1372
Kentucky 1772 1764 2741 1863 2796 2682 2247
New Mexico 902 858 595 787 865 717 74
Missouri 1002 997 118 1192 1131 124 1255
Ohio na na 1804 2198 2693 3254 2165
Wisconsin 286 244 267 293 575 586 625
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 5609 6697 5845 5976 6142 7078 6936
Massachusetts na na na na na na na
New Hampshire 5678 5968 6872 5883 5394 6787 6135
Pennsylvania na na 8374 9102 9010 10100 9983
Rhode Island na na 3567 3829 3527 3880 3262
West Virginia 4628 3889 4229 5489 4642 4832 4034
Kentucky 6756 6687 7517 6234 7613 8444 7205
New Mexico 5291 6842 7036 7402 7345 7672 7123
Missouri 3213 3235 3137 3373 3383 3421 3565
Ohio na na 8696 8789 9859 11432 9300
Wisconsin 2724 2661 3031 3291 4255 4633 5064
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
15 to 24
25 to 34
35 to 54
55 and up
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Male -140 7355 827 901 1286 -927 742 -758 1157 1241 1306 -829 146 301 1082 1242 1306 -1249
Female 841 5151 103 733 1257 -1521 659 -922 533 1204 1494 -1014 -132 1299 229 1331 1617 -1214
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 4888 4820 8365 9057 9873 11142 10110
Female 3201 3470 5257 5312 5701 6418 5442
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 3611 3879 3585 40 4496 5083 4662
Female 159 1695 1538 162 1816 2087 1875
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 2295 2328 2399 2658 2988 3379 2957
Female 839 828 936 957 1085 126 1107
Q1 2016 Q2 2016 Q3 2016 Q4 2016 Q1 2017 Q2 2017 Q3 2017 q1 q2 q3
All drug 3948 4061 6589 6894 7458 8430 7696 889150252325 1075831326045 167997701832
Heroin 1452 1472 1571 1681 1891 2173 191 302341597796 476222826087 215786123488
Opioid 2447 2636 2429 2636 2956 3382 3088 208009807928 283004552352 271305063812
Q12016-Q12017 Q22016-Q22017 Q32016-Q32017
All drug 889150252325 1075831326045 167997701832
Heroin 302341597796 476222826087 215786123488
Opioid 208009807928 283004552352 271305063812
Page 48: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease
All drug
Heroin
Opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Summary

Stable increases for all drug and heroin from Q1 2016 to Q3 2017- Opioid had stable increases from Q3 2016 to Q2 2017

Moderate decreases from Q2 to Q3 2017- 9 for all drug 9 for opioid and 12 for heroin

Annual percentage changes were above 15 increases- Q1 to Q1 89 all drug 30 heroin amp 21 opioid- Q2 to Q2 108 all drug 48 heroin amp 28 opioid- Q3 to Q3 17 all drug 22 heroin amp 27 opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency department data dissemination efforts

ldquoOpioid Overdoses Treated in Emergency Departmentsrdquo -httpswwwcdcgovvitalsignsopioid-overdosesindexhtml

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose

Reporting System

Presenter Julie OrsquoDonnell PhD MPHEpidemiologist

Centers for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Alana Vivolo-Kantor R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Julie OrsquoDonnell PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Increase in deaths outpaces increase in use

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid

overdose

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid overdose surveillance

Track specific substances contributing to overdose deaths

Detect newly-emerging substances involved in overdose

Determine risk factors circumstances associated with fatal overdose

Assess common drug combinations Provide more timely data on overdose deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

State Unintentional Drug Overdose Reporting System (SUDORS)

Death certificates

Medical examiner

coroner reportsToxicology

reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data submitted bi-annually

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

1 Data entry started

2 Data entry finished

1 Data entry started

2 Data entry finished

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS leverages National Violent Death Reporting System (NVDRS) platform

- Basic descriptors- Compare across demographics

- Recent release from institution- Overdose location - Survival time

- Mental health diagnoses- Substance abuse treatment history

- Substances present- Substances contributing to death

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Maine 1941 -1273 225 278 1523 -201 3951 -692 257 -813 2945 981 793 656 -299 -2255 3199 2197
Massachusetts na na na na na na 1561 -157 -848 -1148 311 1897 553 -31 -13 -1632 456 2146
New Hampshire 511 1514 -1438 -832 2583 -961 318 64 -433 -1791 2967 -876 825 -184 -1002 -2016 3363 -17
Pennsylvania na na 869 -102 1211 -116 na na 2979 1751 2589 -594 na na 2601 1534 2735 -735
Rhode Island na na 735 -790 1002 -1594 na na 28 454 544 -1191 na na 121 1057 566 -3262
West Virginia -1596 875 2978 -1543 409 -1651 -367 995 4331 -1664 402 -2377 -769 1847 4571 -1584 -199 -3022
Kentucky -102 1242 -1707 2211 1092 -1468 1095 5192 -2694 4045 352 -2002 -043 5541 -3206 5012 -408 -1624
New Mexico 2932 283 521 -078 445 -716 255 -1298 2611 151 -501 -1093 -487 -3061 3227 987 -1715 323
Missouri 068 -304 754 028 114 421 292 827 477 -177 954 767 -046 1839 096 -512 966 125
Ohio na na 107 1216 1596 -1865 na na 2274 2567 2167 -3194 na na 2182 2254 2086 -3348
Wisconsin -229 1388 861 2928 888 931 -948 986 1712 6728 322 314 -1457 91 983 9621 196 668
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 1514 2112 1966 2017 1853 2398 2634
Massachusetts 7036 8133 8006 7327 6486 6687 7956
New Hampshire 3806 3927 4179 3998 3282 4255 3882
Pennsylvania na na 1265 1641 1929 2428 2284
Rhode Island na na 1498 154 161 1698 1496
West Virginia 2258 2176 2392 3428 2857 2972 2266
Kentucky 2095 2325 3532 258 3624 3752 3001
New Mexico 1927 1976 1719 2168 2201 2091 1862
Missouri 1472 1515 1641 1719 1688 185 1991
Ohio na na 236 2897 3641 443 3015
Wisconsin 664 601 66 773 1294 1336 1377
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 502 9 959 931 721 952 1161
Massachusetts 4035 4258 4126 359 3004 3141 3815
New Hampshire 2514 2721 2671 2403 1919 2564 2128
Pennsylvania na na 1013 1277 1473 1876 1738
Rhode Island na na 803 812 898 949 639
West Virginia 1496 1381 1636 2384 2006 1966 1372
Kentucky 1772 1764 2741 1863 2796 2682 2247
New Mexico 902 858 595 787 865 717 74
Missouri 1002 997 118 1192 1131 124 1255
Ohio na na 1804 2198 2693 3254 2165
Wisconsin 286 244 267 293 575 586 625
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 5609 6697 5845 5976 6142 7078 6936
Massachusetts na na na na na na na
New Hampshire 5678 5968 6872 5883 5394 6787 6135
Pennsylvania na na 8374 9102 9010 10100 9983
Rhode Island na na 3567 3829 3527 3880 3262
West Virginia 4628 3889 4229 5489 4642 4832 4034
Kentucky 6756 6687 7517 6234 7613 8444 7205
New Mexico 5291 6842 7036 7402 7345 7672 7123
Missouri 3213 3235 3137 3373 3383 3421 3565
Ohio na na 8696 8789 9859 11432 9300
Wisconsin 2724 2661 3031 3291 4255 4633 5064
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
15 to 24
25 to 34
35 to 54
55 and up
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Male -140 7355 827 901 1286 -927 742 -758 1157 1241 1306 -829 146 301 1082 1242 1306 -1249
Female 841 5151 103 733 1257 -1521 659 -922 533 1204 1494 -1014 -132 1299 229 1331 1617 -1214
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 4888 4820 8365 9057 9873 11142 10110
Female 3201 3470 5257 5312 5701 6418 5442
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 3611 3879 3585 40 4496 5083 4662
Female 159 1695 1538 162 1816 2087 1875
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 2295 2328 2399 2658 2988 3379 2957
Female 839 828 936 957 1085 126 1107
Page 49: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

Summary

Stable increases for all drug and heroin from Q1 2016 to Q3 2017- Opioid had stable increases from Q3 2016 to Q2 2017

Moderate decreases from Q2 to Q3 2017- 9 for all drug 9 for opioid and 12 for heroin

Annual percentage changes were above 15 increases- Q1 to Q1 89 all drug 30 heroin amp 21 opioid- Q2 to Q2 108 all drug 48 heroin amp 28 opioid- Q3 to Q3 17 all drug 22 heroin amp 27 opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency department data dissemination efforts

ldquoOpioid Overdoses Treated in Emergency Departmentsrdquo -httpswwwcdcgovvitalsignsopioid-overdosesindexhtml

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose

Reporting System

Presenter Julie OrsquoDonnell PhD MPHEpidemiologist

Centers for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Alana Vivolo-Kantor R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Julie OrsquoDonnell PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Increase in deaths outpaces increase in use

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid

overdose

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid overdose surveillance

Track specific substances contributing to overdose deaths

Detect newly-emerging substances involved in overdose

Determine risk factors circumstances associated with fatal overdose

Assess common drug combinations Provide more timely data on overdose deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

State Unintentional Drug Overdose Reporting System (SUDORS)

Death certificates

Medical examiner

coroner reportsToxicology

reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data submitted bi-annually

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

1 Data entry started

2 Data entry finished

1 Data entry started

2 Data entry finished

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS leverages National Violent Death Reporting System (NVDRS) platform

- Basic descriptors- Compare across demographics

- Recent release from institution- Overdose location - Survival time

- Mental health diagnoses- Substance abuse treatment history

- Substances present- Substances contributing to death

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Maine 1941 -1273 225 278 1523 -201 3951 -692 257 -813 2945 981 793 656 -299 -2255 3199 2197
Massachusetts na na na na na na 1561 -157 -848 -1148 311 1897 553 -31 -13 -1632 456 2146
New Hampshire 511 1514 -1438 -832 2583 -961 318 64 -433 -1791 2967 -876 825 -184 -1002 -2016 3363 -17
Pennsylvania na na 869 -102 1211 -116 na na 2979 1751 2589 -594 na na 2601 1534 2735 -735
Rhode Island na na 735 -790 1002 -1594 na na 28 454 544 -1191 na na 121 1057 566 -3262
West Virginia -1596 875 2978 -1543 409 -1651 -367 995 4331 -1664 402 -2377 -769 1847 4571 -1584 -199 -3022
Kentucky -102 1242 -1707 2211 1092 -1468 1095 5192 -2694 4045 352 -2002 -043 5541 -3206 5012 -408 -1624
New Mexico 2932 283 521 -078 445 -716 255 -1298 2611 151 -501 -1093 -487 -3061 3227 987 -1715 323
Missouri 068 -304 754 028 114 421 292 827 477 -177 954 767 -046 1839 096 -512 966 125
Ohio na na 107 1216 1596 -1865 na na 2274 2567 2167 -3194 na na 2182 2254 2086 -3348
Wisconsin -229 1388 861 2928 888 931 -948 986 1712 6728 322 314 -1457 91 983 9621 196 668
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 1514 2112 1966 2017 1853 2398 2634
Massachusetts 7036 8133 8006 7327 6486 6687 7956
New Hampshire 3806 3927 4179 3998 3282 4255 3882
Pennsylvania na na 1265 1641 1929 2428 2284
Rhode Island na na 1498 154 161 1698 1496
West Virginia 2258 2176 2392 3428 2857 2972 2266
Kentucky 2095 2325 3532 258 3624 3752 3001
New Mexico 1927 1976 1719 2168 2201 2091 1862
Missouri 1472 1515 1641 1719 1688 185 1991
Ohio na na 236 2897 3641 443 3015
Wisconsin 664 601 66 773 1294 1336 1377
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 502 9 959 931 721 952 1161
Massachusetts 4035 4258 4126 359 3004 3141 3815
New Hampshire 2514 2721 2671 2403 1919 2564 2128
Pennsylvania na na 1013 1277 1473 1876 1738
Rhode Island na na 803 812 898 949 639
West Virginia 1496 1381 1636 2384 2006 1966 1372
Kentucky 1772 1764 2741 1863 2796 2682 2247
New Mexico 902 858 595 787 865 717 74
Missouri 1002 997 118 1192 1131 124 1255
Ohio na na 1804 2198 2693 3254 2165
Wisconsin 286 244 267 293 575 586 625
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 5609 6697 5845 5976 6142 7078 6936
Massachusetts na na na na na na na
New Hampshire 5678 5968 6872 5883 5394 6787 6135
Pennsylvania na na 8374 9102 9010 10100 9983
Rhode Island na na 3567 3829 3527 3880 3262
West Virginia 4628 3889 4229 5489 4642 4832 4034
Kentucky 6756 6687 7517 6234 7613 8444 7205
New Mexico 5291 6842 7036 7402 7345 7672 7123
Missouri 3213 3235 3137 3373 3383 3421 3565
Ohio na na 8696 8789 9859 11432 9300
Wisconsin 2724 2661 3031 3291 4255 4633 5064
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
15 to 24
25 to 34
35 to 54
55 and up
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Male -140 7355 827 901 1286 -927 742 -758 1157 1241 1306 -829 146 301 1082 1242 1306 -1249
Female 841 5151 103 733 1257 -1521 659 -922 533 1204 1494 -1014 -132 1299 229 1331 1617 -1214
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 4888 4820 8365 9057 9873 11142 10110
Female 3201 3470 5257 5312 5701 6418 5442
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 3611 3879 3585 40 4496 5083 4662
Female 159 1695 1538 162 1816 2087 1875
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Male 2295 2328 2399 2658 2988 3379 2957
Female 839 828 936 957 1085 126 1107
Page 50: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

Summary

Stable increases for all drug and heroin from Q1 2016 to Q3 2017- Opioid had stable increases from Q3 2016 to Q2 2017

Moderate decreases from Q2 to Q3 2017- 9 for all drug 9 for opioid and 12 for heroin

Annual percentage changes were above 15 increases- Q1 to Q1 89 all drug 30 heroin amp 21 opioid- Q2 to Q2 108 all drug 48 heroin amp 28 opioid- Q3 to Q3 17 all drug 22 heroin amp 27 opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency department data dissemination efforts

ldquoOpioid Overdoses Treated in Emergency Departmentsrdquo -httpswwwcdcgovvitalsignsopioid-overdosesindexhtml

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose

Reporting System

Presenter Julie OrsquoDonnell PhD MPHEpidemiologist

Centers for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Alana Vivolo-Kantor R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Julie OrsquoDonnell PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Increase in deaths outpaces increase in use

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid

overdose

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid overdose surveillance

Track specific substances contributing to overdose deaths

Detect newly-emerging substances involved in overdose

Determine risk factors circumstances associated with fatal overdose

Assess common drug combinations Provide more timely data on overdose deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

State Unintentional Drug Overdose Reporting System (SUDORS)

Death certificates

Medical examiner

coroner reportsToxicology

reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data submitted bi-annually

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

1 Data entry started

2 Data entry finished

1 Data entry started

2 Data entry finished

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS leverages National Violent Death Reporting System (NVDRS) platform

- Basic descriptors- Compare across demographics

- Recent release from institution- Overdose location - Survival time

- Mental health diagnoses- Substance abuse treatment history

- Substances present- Substances contributing to death

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Maine 1941 -1273 225 278 1523 -201 3951 -692 257 -813 2945 981 793 656 -299 -2255 3199 2197
Massachusetts na na na na na na 1561 -157 -848 -1148 311 1897 553 -31 -13 -1632 456 2146
New Hampshire 511 1514 -1438 -832 2583 -961 318 64 -433 -1791 2967 -876 825 -184 -1002 -2016 3363 -17
Pennsylvania na na 869 -102 1211 -116 na na 2979 1751 2589 -594 na na 2601 1534 2735 -735
Rhode Island na na 735 -790 1002 -1594 na na 28 454 544 -1191 na na 121 1057 566 -3262
West Virginia -1596 875 2978 -1543 409 -1651 -367 995 4331 -1664 402 -2377 -769 1847 4571 -1584 -199 -3022
Kentucky -102 1242 -1707 2211 1092 -1468 1095 5192 -2694 4045 352 -2002 -043 5541 -3206 5012 -408 -1624
New Mexico 2932 283 521 -078 445 -716 255 -1298 2611 151 -501 -1093 -487 -3061 3227 987 -1715 323
Missouri 068 -304 754 028 114 421 292 827 477 -177 954 767 -046 1839 096 -512 966 125
Ohio na na 107 1216 1596 -1865 na na 2274 2567 2167 -3194 na na 2182 2254 2086 -3348
Wisconsin -229 1388 861 2928 888 931 -948 986 1712 6728 322 314 -1457 91 983 9621 196 668
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 1514 2112 1966 2017 1853 2398 2634
Massachusetts 7036 8133 8006 7327 6486 6687 7956
New Hampshire 3806 3927 4179 3998 3282 4255 3882
Pennsylvania na na 1265 1641 1929 2428 2284
Rhode Island na na 1498 154 161 1698 1496
West Virginia 2258 2176 2392 3428 2857 2972 2266
Kentucky 2095 2325 3532 258 3624 3752 3001
New Mexico 1927 1976 1719 2168 2201 2091 1862
Missouri 1472 1515 1641 1719 1688 185 1991
Ohio na na 236 2897 3641 443 3015
Wisconsin 664 601 66 773 1294 1336 1377
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 502 9 959 931 721 952 1161
Massachusetts 4035 4258 4126 359 3004 3141 3815
New Hampshire 2514 2721 2671 2403 1919 2564 2128
Pennsylvania na na 1013 1277 1473 1876 1738
Rhode Island na na 803 812 898 949 639
West Virginia 1496 1381 1636 2384 2006 1966 1372
Kentucky 1772 1764 2741 1863 2796 2682 2247
New Mexico 902 858 595 787 865 717 74
Missouri 1002 997 118 1192 1131 124 1255
Ohio na na 1804 2198 2693 3254 2165
Wisconsin 286 244 267 293 575 586 625
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 5609 6697 5845 5976 6142 7078 6936
Massachusetts na na na na na na na
New Hampshire 5678 5968 6872 5883 5394 6787 6135
Pennsylvania na na 8374 9102 9010 10100 9983
Rhode Island na na 3567 3829 3527 3880 3262
West Virginia 4628 3889 4229 5489 4642 4832 4034
Kentucky 6756 6687 7517 6234 7613 8444 7205
New Mexico 5291 6842 7036 7402 7345 7672 7123
Missouri 3213 3235 3137 3373 3383 3421 3565
Ohio na na 8696 8789 9859 11432 9300
Wisconsin 2724 2661 3031 3291 4255 4633 5064
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
15 to 24
25 to 34
35 to 54
55 and up
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
15 to 24
25 to 34
35 to 54
55 and up
Page 51: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

Summary

Stable increases for all drug and heroin from Q1 2016 to Q3 2017- Opioid had stable increases from Q3 2016 to Q2 2017

Moderate decreases from Q2 to Q3 2017- 9 for all drug 9 for opioid and 12 for heroin

Annual percentage changes were above 15 increases- Q1 to Q1 89 all drug 30 heroin amp 21 opioid- Q2 to Q2 108 all drug 48 heroin amp 28 opioid- Q3 to Q3 17 all drug 22 heroin amp 27 opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency department data dissemination efforts

ldquoOpioid Overdoses Treated in Emergency Departmentsrdquo -httpswwwcdcgovvitalsignsopioid-overdosesindexhtml

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose

Reporting System

Presenter Julie OrsquoDonnell PhD MPHEpidemiologist

Centers for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Alana Vivolo-Kantor R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Julie OrsquoDonnell PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Increase in deaths outpaces increase in use

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid

overdose

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid overdose surveillance

Track specific substances contributing to overdose deaths

Detect newly-emerging substances involved in overdose

Determine risk factors circumstances associated with fatal overdose

Assess common drug combinations Provide more timely data on overdose deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

State Unintentional Drug Overdose Reporting System (SUDORS)

Death certificates

Medical examiner

coroner reportsToxicology

reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data submitted bi-annually

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

1 Data entry started

2 Data entry finished

1 Data entry started

2 Data entry finished

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS leverages National Violent Death Reporting System (NVDRS) platform

- Basic descriptors- Compare across demographics

- Recent release from institution- Overdose location - Survival time

- Mental health diagnoses- Substance abuse treatment history

- Substances present- Substances contributing to death

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
all drug all opioids heroin
Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017 Δ fromQ1 2016-Q2 2016 Δ fromQ2 2016-Q3 2016 Δ fromQ3 2016-Q4 2016 Δ fromQ4 2016-Q1 2017 Δ fromQ1 2017-Q2 2017 Δ fromQ2 2017-Q3 2017
Maine 1941 -1273 225 278 1523 -201 3951 -692 257 -813 2945 981 793 656 -299 -2255 3199 2197
Massachusetts na na na na na na 1561 -157 -848 -1148 311 1897 553 -31 -13 -1632 456 2146
New Hampshire 511 1514 -1438 -832 2583 -961 318 64 -433 -1791 2967 -876 825 -184 -1002 -2016 3363 -17
Pennsylvania na na 869 -102 1211 -116 na na 2979 1751 2589 -594 na na 2601 1534 2735 -735
Rhode Island na na 735 -790 1002 -1594 na na 28 454 544 -1191 na na 121 1057 566 -3262
West Virginia -1596 875 2978 -1543 409 -1651 -367 995 4331 -1664 402 -2377 -769 1847 4571 -1584 -199 -3022
Kentucky -102 1242 -1707 2211 1092 -1468 1095 5192 -2694 4045 352 -2002 -043 5541 -3206 5012 -408 -1624
New Mexico 2932 283 521 -078 445 -716 255 -1298 2611 151 -501 -1093 -487 -3061 3227 987 -1715 323
Missouri 068 -304 754 028 114 421 292 827 477 -177 954 767 -046 1839 096 -512 966 125
Ohio na na 107 1216 1596 -1865 na na 2274 2567 2167 -3194 na na 2182 2254 2086 -3348
Wisconsin -229 1388 861 2928 888 931 -948 986 1712 6728 322 314 -1457 91 983 9621 196 668
opioid
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 1514 2112 1966 2017 1853 2398 2634
Massachusetts 7036 8133 8006 7327 6486 6687 7956
New Hampshire 3806 3927 4179 3998 3282 4255 3882
Pennsylvania na na 1265 1641 1929 2428 2284
Rhode Island na na 1498 154 161 1698 1496
West Virginia 2258 2176 2392 3428 2857 2972 2266
Kentucky 2095 2325 3532 258 3624 3752 3001
New Mexico 1927 1976 1719 2168 2201 2091 1862
Missouri 1472 1515 1641 1719 1688 185 1991
Ohio na na 236 2897 3641 443 3015
Wisconsin 664 601 66 773 1294 1336 1377
heroin
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 502 9 959 931 721 952 1161
Massachusetts 4035 4258 4126 359 3004 3141 3815
New Hampshire 2514 2721 2671 2403 1919 2564 2128
Pennsylvania na na 1013 1277 1473 1876 1738
Rhode Island na na 803 812 898 949 639
West Virginia 1496 1381 1636 2384 2006 1966 1372
Kentucky 1772 1764 2741 1863 2796 2682 2247
New Mexico 902 858 595 787 865 717 74
Missouri 1002 997 118 1192 1131 124 1255
Ohio na na 1804 2198 2693 3254 2165
Wisconsin 286 244 267 293 575 586 625
all drug
Q1 2016 rate Q2 2016 rate Q3 2016 rate Q4 2016 rate Q1 2017 rate Q2 2017 rate Q3 2017 rate
Maine 5609 6697 5845 5976 6142 7078 6936
Massachusetts na na na na na na na
New Hampshire 5678 5968 6872 5883 5394 6787 6135
Pennsylvania na na 8374 9102 9010 10100 9983
Rhode Island na na 3567 3829 3527 3880 3262
West Virginia 4628 3889 4229 5489 4642 4832 4034
Kentucky 6756 6687 7517 6234 7613 8444 7205
New Mexico 5291 6842 7036 7402 7345 7672 7123
Missouri 3213 3235 3137 3373 3383 3421 3565
Ohio na na 8696 8789 9859 11432 9300
Wisconsin 2724 2661 3031 3291 4255 4633 5064
Page 52: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

Summary

Stable increases for all drug and heroin from Q1 2016 to Q3 2017- Opioid had stable increases from Q3 2016 to Q2 2017

Moderate decreases from Q2 to Q3 2017- 9 for all drug 9 for opioid and 12 for heroin

Annual percentage changes were above 15 increases- Q1 to Q1 89 all drug 30 heroin amp 21 opioid- Q2 to Q2 108 all drug 48 heroin amp 28 opioid- Q3 to Q3 17 all drug 22 heroin amp 27 opioid

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency department data dissemination efforts

ldquoOpioid Overdoses Treated in Emergency Departmentsrdquo -httpswwwcdcgovvitalsignsopioid-overdosesindexhtml

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose

Reporting System

Presenter Julie OrsquoDonnell PhD MPHEpidemiologist

Centers for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Alana Vivolo-Kantor R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Julie OrsquoDonnell PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Increase in deaths outpaces increase in use

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid

overdose

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid overdose surveillance

Track specific substances contributing to overdose deaths

Detect newly-emerging substances involved in overdose

Determine risk factors circumstances associated with fatal overdose

Assess common drug combinations Provide more timely data on overdose deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

State Unintentional Drug Overdose Reporting System (SUDORS)

Death certificates

Medical examiner

coroner reportsToxicology

reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data submitted bi-annually

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

1 Data entry started

2 Data entry finished

1 Data entry started

2 Data entry finished

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS leverages National Violent Death Reporting System (NVDRS) platform

- Basic descriptors- Compare across demographics

- Recent release from institution- Overdose location - Survival time

- Mental health diagnoses- Substance abuse treatment history

- Substances present- Substances contributing to death

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Page 53: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency department data dissemination efforts

ldquoOpioid Overdoses Treated in Emergency Departmentsrdquo -httpswwwcdcgovvitalsignsopioid-overdosesindexhtml

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose

Reporting System

Presenter Julie OrsquoDonnell PhD MPHEpidemiologist

Centers for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Alana Vivolo-Kantor R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Julie OrsquoDonnell PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Increase in deaths outpaces increase in use

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid

overdose

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid overdose surveillance

Track specific substances contributing to overdose deaths

Detect newly-emerging substances involved in overdose

Determine risk factors circumstances associated with fatal overdose

Assess common drug combinations Provide more timely data on overdose deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

State Unintentional Drug Overdose Reporting System (SUDORS)

Death certificates

Medical examiner

coroner reportsToxicology

reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data submitted bi-annually

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

1 Data entry started

2 Data entry finished

1 Data entry started

2 Data entry finished

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS leverages National Violent Death Reporting System (NVDRS) platform

- Basic descriptors- Compare across demographics

- Recent release from institution- Overdose location - Survival time

- Mental health diagnoses- Substance abuse treatment history

- Substances present- Substances contributing to death

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Page 54: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

Emergency department data dissemination efforts

ldquoOpioid Overdoses Treated in Emergency Departmentsrdquo -httpswwwcdcgovvitalsignsopioid-overdosesindexhtml

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose

Reporting System

Presenter Julie OrsquoDonnell PhD MPHEpidemiologist

Centers for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Alana Vivolo-Kantor R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Julie OrsquoDonnell PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Increase in deaths outpaces increase in use

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid

overdose

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid overdose surveillance

Track specific substances contributing to overdose deaths

Detect newly-emerging substances involved in overdose

Determine risk factors circumstances associated with fatal overdose

Assess common drug combinations Provide more timely data on overdose deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

State Unintentional Drug Overdose Reporting System (SUDORS)

Death certificates

Medical examiner

coroner reportsToxicology

reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data submitted bi-annually

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

1 Data entry started

2 Data entry finished

1 Data entry started

2 Data entry finished

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS leverages National Violent Death Reporting System (NVDRS) platform

- Basic descriptors- Compare across demographics

- Recent release from institution- Overdose location - Survival time

- Mental health diagnoses- Substance abuse treatment history

- Substances present- Substances contributing to death

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Page 55: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose

Reporting System

Presenter Julie OrsquoDonnell PhD MPHEpidemiologist

Centers for Disease Control and Prevention

Co-authors Christine Mattson Puja Seth Alana Vivolo-Kantor R Matthew Gladden

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Julie OrsquoDonnell PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Increase in deaths outpaces increase in use

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid

overdose

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid overdose surveillance

Track specific substances contributing to overdose deaths

Detect newly-emerging substances involved in overdose

Determine risk factors circumstances associated with fatal overdose

Assess common drug combinations Provide more timely data on overdose deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

State Unintentional Drug Overdose Reporting System (SUDORS)

Death certificates

Medical examiner

coroner reportsToxicology

reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data submitted bi-annually

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

1 Data entry started

2 Data entry finished

1 Data entry started

2 Data entry finished

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS leverages National Violent Death Reporting System (NVDRS) platform

- Basic descriptors- Compare across demographics

- Recent release from institution- Overdose location - Survival time

- Mental health diagnoses- Substance abuse treatment history

- Substances present- Substances contributing to death

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Page 56: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

Disclosure Statement

Julie OrsquoDonnell PhD has disclosed no relevant real or apparent personal or professional financial relationships with proprietary entities that produce health care goods and services

Disclaimer The findings and conclusions are those of the presenter and do not necessarily represent the official position of the Centers for Disease Control

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Increase in deaths outpaces increase in use

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid

overdose

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid overdose surveillance

Track specific substances contributing to overdose deaths

Detect newly-emerging substances involved in overdose

Determine risk factors circumstances associated with fatal overdose

Assess common drug combinations Provide more timely data on overdose deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

State Unintentional Drug Overdose Reporting System (SUDORS)

Death certificates

Medical examiner

coroner reportsToxicology

reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data submitted bi-annually

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

1 Data entry started

2 Data entry finished

1 Data entry started

2 Data entry finished

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS leverages National Violent Death Reporting System (NVDRS) platform

- Basic descriptors- Compare across demographics

- Recent release from institution- Overdose location - Survival time

- Mental health diagnoses- Substance abuse treatment history

- Substances present- Substances contributing to death

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Page 57: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

Rx Summit wwwNationalRxDrugAbuseSummitorg

Increase in deaths outpaces increase in use

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid

overdose

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid overdose surveillance

Track specific substances contributing to overdose deaths

Detect newly-emerging substances involved in overdose

Determine risk factors circumstances associated with fatal overdose

Assess common drug combinations Provide more timely data on overdose deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

State Unintentional Drug Overdose Reporting System (SUDORS)

Death certificates

Medical examiner

coroner reportsToxicology

reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data submitted bi-annually

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

1 Data entry started

2 Data entry finished

1 Data entry started

2 Data entry finished

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS leverages National Violent Death Reporting System (NVDRS) platform

- Basic descriptors- Compare across demographics

- Recent release from institution- Overdose location - Survival time

- Mental health diagnoses- Substance abuse treatment history

- Substances present- Substances contributing to death

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Page 58: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

Increase in deaths outpaces increase in use

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid

overdose

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid overdose surveillance

Track specific substances contributing to overdose deaths

Detect newly-emerging substances involved in overdose

Determine risk factors circumstances associated with fatal overdose

Assess common drug combinations Provide more timely data on overdose deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

State Unintentional Drug Overdose Reporting System (SUDORS)

Death certificates

Medical examiner

coroner reportsToxicology

reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data submitted bi-annually

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

1 Data entry started

2 Data entry finished

1 Data entry started

2 Data entry finished

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS leverages National Violent Death Reporting System (NVDRS) platform

- Basic descriptors- Compare across demographics

- Recent release from institution- Overdose location - Survival time

- Mental health diagnoses- Substance abuse treatment history

- Substances present- Substances contributing to death

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Page 59: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid

overdose

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid overdose surveillance

Track specific substances contributing to overdose deaths

Detect newly-emerging substances involved in overdose

Determine risk factors circumstances associated with fatal overdose

Assess common drug combinations Provide more timely data on overdose deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

State Unintentional Drug Overdose Reporting System (SUDORS)

Death certificates

Medical examiner

coroner reportsToxicology

reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data submitted bi-annually

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

1 Data entry started

2 Data entry finished

1 Data entry started

2 Data entry finished

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS leverages National Violent Death Reporting System (NVDRS) platform

- Basic descriptors- Compare across demographics

- Recent release from institution- Overdose location - Survival time

- Mental health diagnoses- Substance abuse treatment history

- Substances present- Substances contributing to death

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Page 60: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

Fatal opioid overdose surveillance

Track specific substances contributing to overdose deaths

Detect newly-emerging substances involved in overdose

Determine risk factors circumstances associated with fatal overdose

Assess common drug combinations Provide more timely data on overdose deaths

Rx Summit wwwNationalRxDrugAbuseSummitorg

State Unintentional Drug Overdose Reporting System (SUDORS)

Death certificates

Medical examiner

coroner reportsToxicology

reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data submitted bi-annually

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

1 Data entry started

2 Data entry finished

1 Data entry started

2 Data entry finished

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS leverages National Violent Death Reporting System (NVDRS) platform

- Basic descriptors- Compare across demographics

- Recent release from institution- Overdose location - Survival time

- Mental health diagnoses- Substance abuse treatment history

- Substances present- Substances contributing to death

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Page 61: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

State Unintentional Drug Overdose Reporting System (SUDORS)

Death certificates

Medical examiner

coroner reportsToxicology

reports

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data submitted bi-annually

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

1 Data entry started

2 Data entry finished

1 Data entry started

2 Data entry finished

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS leverages National Violent Death Reporting System (NVDRS) platform

- Basic descriptors- Compare across demographics

- Recent release from institution- Overdose location - Survival time

- Mental health diagnoses- Substance abuse treatment history

- Substances present- Substances contributing to death

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Page 62: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data submitted bi-annually

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

1 Data entry started

2 Data entry finished

1 Data entry started

2 Data entry finished

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS leverages National Violent Death Reporting System (NVDRS) platform

- Basic descriptors- Compare across demographics

- Recent release from institution- Overdose location - Survival time

- Mental health diagnoses- Substance abuse treatment history

- Substances present- Substances contributing to death

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Page 63: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS leverages National Violent Death Reporting System (NVDRS) platform

- Basic descriptors- Compare across demographics

- Recent release from institution- Overdose location - Survival time

- Mental health diagnoses- Substance abuse treatment history

- Substances present- Substances contributing to death

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Page 64: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Page 65: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Page 66: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Page 67: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Page 68: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Page 69: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Page 70: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Page 71: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

Overdose-specific fields

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Page 72: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

Toxicology information

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Page 73: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS data as good as sources allow

Death Certificates

- Drug specificity- Time lag in

cause of death codes

Medical Examiner Coroner Reports

- Scene evidence availability

- Death scene investigation

Toxicology Reports

- Testing availability

- Emerging substances

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Page 74: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

Despite limitations SUDORS data have many strengths

Most states census of unintentional and undetermined intent opioid overdose deaths- Data on count of deaths within 6 months

Flexibility to include substances contributing to death outside of death certificate textcode fields

Overdose-specific circumstance data collected within 8 months

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Page 75: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

Preliminary results

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Page 76: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Page 77: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Page 78: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
Page 79: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017

Cohort 1 states (N=10)

Preliminary resultsMissouri Pennsylvania data not available

Total deaths (20162017)10699

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Page 80: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Chart1

Series 1
Time Period
Number of Deaths
5592
5377

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
1st half 2017
2nd half 2016
Page 81: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Sheet1

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Series 1 Series 2 Series 3
1st half 2017 5592 24 2
2nd half 2016 5377 44 2
Category 3 35 18 3
Category 4 45 28 5
Page 82: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

Number of opioid overdose deaths by state and reporting period

Preliminary results

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Page 83: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Chart1

2nd-half 2016
1st-half 2017
State
Number of deaths
524
646
156
144
1108
883
193
205
166
155
2063
2389
210
214
145
120
394
442
418
394

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
KY KY
ME ME
MA MA
NH NH
NM NM
OH OH
OK OK
RI RI
WV WV
WI WI
Page 84: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Sheet1

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
KY-2016 KY-2017 ME-2016 ME-2017 MA-2016 MA-2017 MO-2016 MO-2017 NH-2016 NH-2017 NM-2016 NM-2017 OH-2016 OH-2017 OK-2016 OK-2017 PA-2016 PA-2017 RI-2016 RI-2017 WV-2016 WV-2017 WI-2016 WI-2017
IMF 171 82 60 708 596 236 84 132 146 13 11 996 1291 8 11 695 1002 79 48 164 205 106 96
Rx fent 5 1 1 3 1 5 2 1 0 6 0 5 2 11 11 5 2 3 1 2 0 7 3
Page 85: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Sheet1

IMF
Rx fent

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
Page 86: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Sheet2

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
KY ME MA MO NH NM OH OK PA RI WV WI
2016 000 2821 163 070 1244 663 2648 095 490 205 2030 407
2017 2986 136 000 1485 024 4641 235 1894 885 2902 1804
Page 87: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Sheet2

2016
2017

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
Page 88: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Sheet3

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
opioid deaths overall
KY ME MA MO NH NM OH OK PA RI WV WI
2nd-half 2016 524 156 1108 427 193 166 2063 210 1388 145 394 418 7192
1st-half 2017 646 144 883 127 205 155 2389 214 1452 120 442 394 7171
14363
14522
Page 89: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Sheet3

2nd-half 2016
1st-half 2017
State
Number of deaths

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
Page 90: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Regional

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
2016 and 2017 data combined (KY currently doesnt have any 2017 data in there)
of all opioid deaths with these categories as cause of death (not mutually exclusive) of each drug category with circumstances
KY ME MA MO NH NM OH OK PA RI WV WI Prescription Heroin Fentanyl
Prescription 097 3133 2163 2166 1519 4860 1954 6525 2447 3861 4014 3375 Recent release 789 1151 993
Heroin 4854 3700 3737 4224 886 5701 3581 2435 5032 2317 3860 6117 Prior OD 1023 1234 1331
Fentanyl 7467 7716 6264 8759 1215 7708 1820 7415 7027 6615 3598 Current treatment 980 836 755
Recent opioid use relapse 755 1620 1296
History of heroin abuse 1946 4259 3926
History of Rx opioid abuse 1434 361 393
History of Rx opioid AND heroin abuse 541 656 603
Page 91: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Regional

Prescription
Heroin
Fentanyl
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
Page 92: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease
Prescription
Heroin
Fentanyl

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
Page 93: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

Most common prescription opioids involved in opioid overdose deaths

Prescription opioids3285 (30) deaths

Oxycodone1331 (41)

Hydrocodone576 (18)

Methadone542 (17)

Morphine448 (14)

Buprenorphine374 (11)

Oxymorphone334 (10)

Preliminary results

Substances listed as cause of death count does not include fentanyl categories not mutually exclusive

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
Page 94: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

Redefining morphine as heroin using scene and toxicology evidence

MorphineOriginal 4569 (42)Recoded 557 (6)

HeroinConfirmed 3437 (31)

Probable 813 (7)Suspected 0

Heroin- Confirmed heroin-positive- Probable morphine-positive evidence of injectionheroin useillicit drug use and no

evidence of prescription morphine use- Suspected morphine-positive no scene evidence heroin listed as cause of death

Morphine recoded morphine-positive not confirmedprobablesuspected heroin

Unknown morphine-positive no scene evidence

Preliminary results

Unknown386 (4)

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
Page 95: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

SUDORS Data

Drug potency

Polysubstance use

Route of administration

Overdose response

Health conditions

comorbidities

Capturing fentanyl analogs

All substances

present

Scene evidence indicating route(s)

Bystanders present naloxone

administration

Pain treatment

comorbidities

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
Page 96: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

Acknowledgments

State health departments participating in CDCrsquos Enhanced State Opioid Overdose Surveillance (ESOOS) program

State and local jurisdictions participating in CDCrsquos National Syndromic Surveillance Program (NSSP)BioSense ESSENCE

CDC ESOOS staff- Puja Seth- Reshma Mahendra- Alana Vivolo-Kantor- Christine Mattson- Shelby Alexander- Sabeen Bhimani- Felicita David- Naomi David- Terry Davis- Matthew Gladden- John Halpin

- Brooke Hoots- Mbabazi Kariisa- Stephen Liu- Londell McGlone- Julie OrsquoDonnell- Anita Pullani- Rose Rudd- Lawrence Scholl- Jessica Simpson- Nana Wilson

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
Page 97: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

Rx Summit wwwNationalRxDrugAbuseSummitorg

Faster Data The CDC-Funded Enhanced State Opioid Overdose

Surveillance ProgramPuja Seth PhD Lead Overdose Epidemiology and Surveillance Team

Centers for Disease Control and Prevention (CDC)

Alana Vivolo-Kantor PhD MPH Behavioral Scientist CDC

Julie ODonnell PhD MPH Epidemiologist CDC

Federal Track

Moderator Puja Seth

THANK YOURxSummit

wwwNationalRxDrugAbuseSummitorg

  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69
Page 98: Faster Data: The CDC-Funded Enhanced State …Enhanced State Opioid Overdose Surveillance Program Puja Seth, PhD, Lead, Overdose Epidemiology and Surveillance Team, Centers for Disease

THANK YOURxSummit

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  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Disclosures
  • Disclosures
  • Learning Objectives
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program (ESOOS)
  • Disclosure Statement
  • Goals
  • Opioid Overdoses Treated in Emergency Departments
  • Slide Number 9
  • Slide Number 10
  • Slide Number 11
  • Slide Number 12
  • Slide Number 13
  • Slide Number 14
  • CDCrsquos Pillars on Opioids
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Enhanced State Opioid Overdose Surveillance (ESOOS)
  • Funded ESOOS states
  • Slide Number 19
  • Next Two Presentationshellip
  • The utilization of emergency department syndromic surveillance and emergency medical services data to monitor nonfatal opioid overdoses
  • Disclosure Statement
  • Why Emergency Department and Emergency Medical Service Data for Surveillance
  • Our Philosophy
  • Our approach
  • Emergency Department Data
  • Case definitions for suspected overdose
  • Emergency medical services data
  • Challenges in EMS data
  • Data submission process
  • Sample quality control report
  • Sample site report
  • ED results All drug (11 sites)
  • ED results Opioid (11 sites)
  • ED results Heroin (11 sites)
  • Annual percentage changes (11 sites)
  • Summary
  • Slide Number 38
  • Emergency department data dissemination efforts
  • Fatal Opioid Overdose SurveillanceThe State Unintentional Drug Overdose Reporting System
  • Disclosure Statement
  • Slide Number 42
  • Increase in deaths outpaces increase in use
  • Slide Number 44
  • Fatal opioid overdose surveillance
  • Slide Number 46
  • SUDORS data submitted bi-annually
  • SUDORS leverages National Violent Death Reporting System (NVDRS) platform
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Overdose-specific fields
  • Toxicology information
  • SUDORS data as good as sources allow
  • Despite limitations SUDORS data have many strengths
  • Preliminary results
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths increasing 2nd-half 2016 to 1st-half 2017
  • Number of opioid overdose deaths by state and reporting period
  • Most common prescription opioids involved in opioid overdose deaths
  • Redefining morphine as heroin using scene and toxicology evidence
  • Slide Number 66
  • Acknowledgments
  • Faster Data The CDC-Funded Enhanced State Opioid Overdose Surveillance Program
  • Slide Number 69