Challenges of central neuraxial anaesthesia and sedation ...
Failed neuraxial anaesthsia- what now?
Transcript of Failed neuraxial anaesthsia- what now?
![Page 1: Failed neuraxial anaesthsia- what now?](https://reader030.fdocuments.in/reader030/viewer/2022020620/61e4288d9480a14ecb37b69f/html5/thumbnails/1.jpg)
Failed neuraxial
anaesthsia- what
now?
Dr. Moira Baeriswyl
![Page 2: Failed neuraxial anaesthsia- what now?](https://reader030.fdocuments.in/reader030/viewer/2022020620/61e4288d9480a14ecb37b69f/html5/thumbnails/2.jpg)
![Page 3: Failed neuraxial anaesthsia- what now?](https://reader030.fdocuments.in/reader030/viewer/2022020620/61e4288d9480a14ecb37b69f/html5/thumbnails/3.jpg)
3
![Page 4: Failed neuraxial anaesthsia- what now?](https://reader030.fdocuments.in/reader030/viewer/2022020620/61e4288d9480a14ecb37b69f/html5/thumbnails/4.jpg)
4
![Page 5: Failed neuraxial anaesthsia- what now?](https://reader030.fdocuments.in/reader030/viewer/2022020620/61e4288d9480a14ecb37b69f/html5/thumbnails/5.jpg)
Unsatisfactory labour epidural ?
5
![Page 6: Failed neuraxial anaesthsia- what now?](https://reader030.fdocuments.in/reader030/viewer/2022020620/61e4288d9480a14ecb37b69f/html5/thumbnails/6.jpg)
Inadequat analgesia (2-20%) Impossible to place KT (13%)
Insufficient analgesia Failure de find epidural space
Asymmetric analgesia (80% = right side )
Failure to thread catheter
Analgesia limited to a small number of segments
Lack of sacral block
Epidural failure ?
Hermanides BJA 2012
![Page 7: Failed neuraxial anaesthsia- what now?](https://reader030.fdocuments.in/reader030/viewer/2022020620/61e4288d9480a14ecb37b69f/html5/thumbnails/7.jpg)
Insufficient analgesia
KT displacement or problem ?
Rapid progression of labour/ End of
labour / Posterior presentation ?
Insuffisant volume of LA ?
![Page 8: Failed neuraxial anaesthsia- what now?](https://reader030.fdocuments.in/reader030/viewer/2022020620/61e4288d9480a14ecb37b69f/html5/thumbnails/8.jpg)
Panni MK. BJA 2006; 106-10
Insuffisant volume of LA ?
![Page 9: Failed neuraxial anaesthsia- what now?](https://reader030.fdocuments.in/reader030/viewer/2022020620/61e4288d9480a14ecb37b69f/html5/thumbnails/9.jpg)
Low correlation between patient size and quantity of LA
necessary
Lower dose of LA in obese patients
Recommandations
4-8 ml
Insuffisant volume of LA ?
![Page 10: Failed neuraxial anaesthsia- what now?](https://reader030.fdocuments.in/reader030/viewer/2022020620/61e4288d9480a14ecb37b69f/html5/thumbnails/10.jpg)
Migration du KT durant le W (54%)
Crosby ET. CJA 1990; 37: 789-93
0
5
10
15
20
25
30
35
40
45
50
>-2 -2 -1,5 -1 -0,5 0 0,5 1 1,5 2 >2
Migration du KT (cm)
Po
urc
en
tag
e d
e p
ati
en
tes
KT displacement ?
![Page 11: Failed neuraxial anaesthsia- what now?](https://reader030.fdocuments.in/reader030/viewer/2022020620/61e4288d9480a14ecb37b69f/html5/thumbnails/11.jpg)
11
![Page 12: Failed neuraxial anaesthsia- what now?](https://reader030.fdocuments.in/reader030/viewer/2022020620/61e4288d9480a14ecb37b69f/html5/thumbnails/12.jpg)
« Lockit »
Clark MK. Anesthesia 2001; 56: 865-870
How to prevent it ?
![Page 13: Failed neuraxial anaesthsia- what now?](https://reader030.fdocuments.in/reader030/viewer/2022020620/61e4288d9480a14ecb37b69f/html5/thumbnails/13.jpg)
Clark MK. Anesthesia 2001; 56: 865-870
Migration du KT Lockit
(n = 48)
Standard
(n = 54)
P
External migration 2 cm 3 (6%) 14 (26%) < 0,01
Internal migration 1 cm 0 (0%) 9 (17%) < 0,01
No significant migration 42 (88%) 15 (28%) < 0,001
« Lockit »
How to prevent it ?
![Page 14: Failed neuraxial anaesthsia- what now?](https://reader030.fdocuments.in/reader030/viewer/2022020620/61e4288d9480a14ecb37b69f/html5/thumbnails/14.jpg)
RR P
Insuffisance analgesia after 1st bolus
3,5 0,001
Posterior presentation 5,6 0,001
Radiculaire pain during epidural 3,9 0,05
Length of epidural analgesia > 6h 9,1 0,001
Length of analgesia < 1h 18,3 0,001
Le Coq G. CJA 1998; 45: 719-23.
Risks factors for insuffisant analgesia
Rapid progression of labour/ End of labour/
Posterior presentation ?
![Page 15: Failed neuraxial anaesthsia- what now?](https://reader030.fdocuments.in/reader030/viewer/2022020620/61e4288d9480a14ecb37b69f/html5/thumbnails/15.jpg)
Adapt analgesia (L2-S5 during expulsion)
Recommandations
- Increase volume
- Increase concentration of LA
- Use adjuvants:
• Sufentanil
• Clonidine (50-75 µg)
Rapid progression of labour/ End of labour/
Posterior presentation ?
![Page 16: Failed neuraxial anaesthsia- what now?](https://reader030.fdocuments.in/reader030/viewer/2022020620/61e4288d9480a14ecb37b69f/html5/thumbnails/16.jpg)
Length of KT
(> 4cm for multi-perforated KT) ?
KT in intervertebral foramen?
KT in anterior epidural space ?
Asymetrical analgesia (80% on right side)
Deformation or spinal surgery?
Septum ou adhesions in epidural space
![Page 17: Failed neuraxial anaesthsia- what now?](https://reader030.fdocuments.in/reader030/viewer/2022020620/61e4288d9480a14ecb37b69f/html5/thumbnails/17.jpg)
KT in intervertebral foramen?
Unilateral analgesia limited to 1-2 dermatome
Collier CB. IJOA 1996; 5: 19-31.
![Page 18: Failed neuraxial anaesthsia- what now?](https://reader030.fdocuments.in/reader030/viewer/2022020620/61e4288d9480a14ecb37b69f/html5/thumbnails/18.jpg)
Septum in epidural space (2%)
Epidural limited to a few
segments
Collier CB. IJOA 1996; 5: 19-31.
![Page 19: Failed neuraxial anaesthsia- what now?](https://reader030.fdocuments.in/reader030/viewer/2022020620/61e4288d9480a14ecb37b69f/html5/thumbnails/19.jpg)
Deformation of spine or spinal surgery ?
Collier CB. IJOA 1996; 5: 19-31.
![Page 20: Failed neuraxial anaesthsia- what now?](https://reader030.fdocuments.in/reader030/viewer/2022020620/61e4288d9480a14ecb37b69f/html5/thumbnails/20.jpg)
Recommandations
- 4-8 ml of LA solution
- pull KT out 1-2 cm
- If insufficient, reposition KT:
• Another level
• Consider a spinal
• Combined Spinal
Asymetrical analgesia
![Page 21: Failed neuraxial anaesthsia- what now?](https://reader030.fdocuments.in/reader030/viewer/2022020620/61e4288d9480a14ecb37b69f/html5/thumbnails/21.jpg)
Failed Spinal before CS ?
23
![Page 22: Failed neuraxial anaesthsia- what now?](https://reader030.fdocuments.in/reader030/viewer/2022020620/61e4288d9480a14ecb37b69f/html5/thumbnails/22.jpg)
24
![Page 23: Failed neuraxial anaesthsia- what now?](https://reader030.fdocuments.in/reader030/viewer/2022020620/61e4288d9480a14ecb37b69f/html5/thumbnails/23.jpg)
• Failed lumbar puncture
• Positioning
• Pseudo-successful puncture
• CSF volume
• Anatomical : septa
25
![Page 24: Failed neuraxial anaesthsia- what now?](https://reader030.fdocuments.in/reader030/viewer/2022020620/61e4288d9480a14ecb37b69f/html5/thumbnails/24.jpg)
26
![Page 25: Failed neuraxial anaesthsia- what now?](https://reader030.fdocuments.in/reader030/viewer/2022020620/61e4288d9480a14ecb37b69f/html5/thumbnails/25.jpg)
• Repeating:
– Insufficient block: lower
dose, higher level
– Unilateral
27
![Page 26: Failed neuraxial anaesthsia- what now?](https://reader030.fdocuments.in/reader030/viewer/2022020620/61e4288d9480a14ecb37b69f/html5/thumbnails/26.jpg)
28
![Page 27: Failed neuraxial anaesthsia- what now?](https://reader030.fdocuments.in/reader030/viewer/2022020620/61e4288d9480a14ecb37b69f/html5/thumbnails/27.jpg)
Grau T. Acta Anaest Scand 2001; 45: 766-71
Control Group (n = 36)
US group (n = 36)
P
Number of puncture attempts 2,6+/- 1,4 1,5 +/- 0,9 P<0,001
Number spinal levels 1,5 +/- 0,7 1,27 +/- 0,51 P<0,05
Number of attempts to insert KT 1,3 +/- 0,6 1,1 +/- 0,6 P<0,003
Patients with asymetric epidural 5 2 n.s
Patients with inequal epidural 3 1 n.s
Failure to place epidural 2 0 n.s
VAS before epidural placement 4,2 +/- 4,1 4,1 +/- 4,1 n.s
VAS max 1,8 +/- 2,7 0,8 +/- 1,4 P<0,035
Patient satisfaction 2,1 +/- 1,3 1,3 +/- 0,5 P<0,006
Headache 4 2 n.s
Back pain 7 7 n.s
Ultrasound in difficult situations
Difficulty in finding the right space ?
![Page 28: Failed neuraxial anaesthsia- what now?](https://reader030.fdocuments.in/reader030/viewer/2022020620/61e4288d9480a14ecb37b69f/html5/thumbnails/28.jpg)
Patients with BMI 33-86 kg/m²
Balki M. Anesth Analg 2009
Difficulty in finding the right space ?
![Page 29: Failed neuraxial anaesthsia- what now?](https://reader030.fdocuments.in/reader030/viewer/2022020620/61e4288d9480a14ecb37b69f/html5/thumbnails/29.jpg)
Facteur Odds ratio 95% CI P
BMI (Kg.m-2)
≥ 30 versus < 30 1,9 1,0 – 3,6 0,03
Abdominal perimeter(cm)
≥ 105 versus < 105 1,5 0,8 – 2,6 0,14
Anatomical level
Grade 3 - 4 versus Grade 1 - 2 1,7 1,0 – 2,9 0,04
Deformation of spine
deformed versus normal 4,3 2,2 – 8,2 < 0,0001
First year internes finding epidural space
Faitot V et al. IJOA 2011; 20: 124-7
Difficulty finding the right space ?
![Page 30: Failed neuraxial anaesthsia- what now?](https://reader030.fdocuments.in/reader030/viewer/2022020620/61e4288d9480a14ecb37b69f/html5/thumbnails/30.jpg)
Failed Top-up before incision
CS ?
32
![Page 31: Failed neuraxial anaesthsia- what now?](https://reader030.fdocuments.in/reader030/viewer/2022020620/61e4288d9480a14ecb37b69f/html5/thumbnails/31.jpg)
33
![Page 32: Failed neuraxial anaesthsia- what now?](https://reader030.fdocuments.in/reader030/viewer/2022020620/61e4288d9480a14ecb37b69f/html5/thumbnails/32.jpg)
34
![Page 33: Failed neuraxial anaesthsia- what now?](https://reader030.fdocuments.in/reader030/viewer/2022020620/61e4288d9480a14ecb37b69f/html5/thumbnails/33.jpg)
35
Spinal General
![Page 34: Failed neuraxial anaesthsia- what now?](https://reader030.fdocuments.in/reader030/viewer/2022020620/61e4288d9480a14ecb37b69f/html5/thumbnails/34.jpg)
Intraoperative pain
with epidural/spinal
• N2O
• Alfentanil
• Ketamine
• Dexmedetomidine
• Remi
36
![Page 35: Failed neuraxial anaesthsia- what now?](https://reader030.fdocuments.in/reader030/viewer/2022020620/61e4288d9480a14ecb37b69f/html5/thumbnails/35.jpg)
What to do then?
• Volume
• Reposition when in doubt
• Deficient spinal: redo
• Ultra-sound
• General anesthesia: safe conditions
40
![Page 36: Failed neuraxial anaesthsia- what now?](https://reader030.fdocuments.in/reader030/viewer/2022020620/61e4288d9480a14ecb37b69f/html5/thumbnails/36.jpg)
41