F. Kurtis Kasper, PhD - School of Dentistry CV 12-2014... · CURRICULUM VITAE. December 8, 2014 ....

CURRICULUM VITAE

December 8, 2014

F. Kurtis Kasper, PhD PRESENT TITLE: Assistant Professor Department of Orthodontics ADDRESS: The University of Texas School of Dentistry at Houston

7500 Cambridge Street, Suite 5130 Houston, TX 77054 Office (713) 486-4174 Fax (713) 486-4123 BIRTHDATE: January 22, 1977 CITIZENSHIP: United States of America UNDERGRADUATE EDUCATION:

1996 Presidential Honors

Phillips University, Enid, OK

1999 Bachelor of Science in Biomedical Engineering Magna Cum Laude, Dean’s High Honors Case Western Reserve University, Cleveland, OH

GRADUATE EDUCATION:

2006 Ph.D. in Bioengineering Thesis Title: Investigation of Oligo (poly(ethylene glycol) fumarate) Hydrogels for Controlled Release of Plasmid DNA Rice University, Houston, TX

POSTGRADUATE TRAINING:

2005-2008 Postdoctoral Research Fellow Rice University, Houston, TX

ACADEMIC APPOINTMENTS:

of 47

July 2014 – Pres Assistant Professor Department of Orthodontics The University of Texas School of Dentistry at Houston, Houston, TX June 2009 – Pres Adjunct Assistant Professor of Oral & Maxillofacial Surgery, Anesthesiology & Oral Pharmacology The University of Texas School of Dentistry at Houston, Houston, TX September 2014 – Pres Scientist Houston Center for Biomaterials and Biomimetics The University of Texas School of Dentistry at Houston, Houston, TX July 2014 – Pres Core Member The Rolanette and Berdon Lawrence Bone Disease Program of Texas July 2014 – Pres Adjunct Assistant Professor Department of Bioengineering Rice University 2013 – Pres Member Gulf Coast Cluster for Regenerative Medicine, The Gulf Coast Consortia July 2008 – June 2014 Faculty Fellow in Bioengineering Rice University, Houston, TX *Promotion to Senior Faculty Fellow in Bioengineering Approved, 2014 LICENSURE: Not applicable CERTIFICATION: Not applicable PROFESSIONAL ORGANIZATIONS:

Local: None Regional: None National: 2011-2013 American Chemical Society (ACS) 2014-Pres American Dental Education Association (ADEA) 2008-2013 American Institute of Chemical Engineers (AIChE)

Dr. F. Kurtis Kasper, PhD of 47

2008-2014 American Society for Engineering Education (ASEE) 2013-2014 ASTM International 2008-Pres Tissue Engineering and Regenerative Medicine International Society (TERMIS)

Membership Committee, North America, 2012-Pres Endorsements Committee, Global, 2011-Pres Vice-chair, Endorsements Committee, Global, 2014-Pres Meetings Committee, North America, 2011-Pres Chair, Local Arrangements Committee, North America, 2011

2008-2013 Biomedical Engineering Society (BMES) 2006-Pres Society For Biomaterials (SFB)

Membership Committee, 2013-Pres Chair, Membership Committee, 2014-Pres

2003-2013 Controlled Release Society (CRS)

HONORS AND AWARDS: Awards 2014 Outstanding Graduate Alumnus Award, Department of Bioengineering, Rice University 2013 Young Investigator Award, Society For Biomaterials 2012 Young Alumnus Award, The Alumni Association of Case Western Reserve University 2011 Young Investigator Award, Tissue Engineering and Regenerative Medicine International

Society – North America 2011 Hershel M. Rich Invention Award, Rice University 2011 Faculty Teaching/Mentoring Award, Rice University 2010 Outstanding Oral Presentation Award, Craniofacial Program, Annual Meeting of the

Armed Forces Institute of Regenerative Medicine, St. Pete Beach, FL 2006 Sallyport Award for University and Community Service, Rice University 1999 Jose Ricardo Alcala Memorial Award for Biomedical Engineering Research, Case Western

Reserve University 1996 Distinguished Freshman Scholar Award, Phillips University 1996 CRC Press Freshman Chemistry Award, Phillips University 1996 United States Achievement Academy All-American Scholar, Phillips University

Honors 2013 Commission as Honorary Admiral in the Texas Navy, Office of the Governor 2013 Invited Protégé, The Academy of Medicine, Engineering & Science of Texas 2013 Invited Panelist, Cell and Tissue Culture Expert Panel, University Space Research

Association, Houston, TX 2013 Invited Keynote Lecture, Biomaterials Day, University of South Dakota, Sioux Falls, SD 2011 Invited Keynote Lecture, Bone-Tec 2011 International Bone Tissue Engineering

Congress, Hannover, Germany 2011 Invited Plenary Lecture, Kyoto University Global COE “Center for Frontier Medicine”

International Symposium, Awaji, Japan 2011 Invited Keynote Lecture, 4th International Conference on Tissue Engineering, Chania,

Crete, Greece 2011 Invited Keynote Lecture, 9th International Symposium on Frontiers in Biomedical

Polymers, Funchal, Portugal 2011 Invited Keynote Lecture, Symposium en Génie Tissulaire, Les Conférences du Centre

LOEX de l’Université Laval, Québec City, Canada 2010 Invited Keynote Lecture, 16th International Biomedical Science and Technology


Symposium, Beşiktaş, İstanbul, Turkey 2009 Invited Keynote Lecture, Honorary Series in Biomaterials, Annual Meeting of the

American Institute of Chemical Engineers, Nashville, TN 2009 Invited Keynote Lecture, World Congress of the Tissue Engineering and Regenerative

Medicine International Society, Seoul, Republic of Korea 2009 Invited Keynote Lecture, Bone-Tec 2009 International Bone Tissue Engineering

Congress, Hannover, Germany 2007 Nanobiology Training Fellow, W.M. Keck Center for Interdisciplinary Bioscience Training,

The Gulf Coast Consortia 2001-03 NSF Integrative Graduate Education and Research Trainee (IGERT), Rice University 1999 Golden Key National Honors Society, Case Western Reserve University 1998 Whitaker Foundation Summer Research Fellowship, Case Western Reserve University 1996 Alpha Lambda Delta National Honors Fraternity, Phillips University

MILITARY AWARDS: Not applicable

EDITORIAL POSTIONS: 2014-Pres Member of Review Editorial Board, Reconstructive and Plastic Surgery 2014-Pres Member of Advisory Board, Journal of Materials Chemistry B 2014-Pres Member of Editorial Board, Journal of Biomedical Materials Research, Part A 2012-Pres Member of Editorial Board, Experimental Biology and Medicine 2011-Pres Member of Editorial Board, Tissue Engineering, Part A 2011-Pres Member of Editorial Board, Tissue Engineering, Part B: Reviews 2011-Pres Member of Editorial Board, Tissue Engineering, Part C: Methods

JOURNAL REVIEWER: Acta Biomaterialia Advanced Healthcare Materials Annals of Biomedical Engineering Biomacromolecules Biomaterials Biomedical Materials Biomedical Microdevices BMC Biotechnology Cellular and Molecular Bioengineering Drug Delivery and Translational Research European Journal of Pharmaceutics and Biopharmaceutics Experimental Biology and Medicine Journal of Applied Polymer Science Journal of Biomedical Materials Research, Part A Journal of Biomedical Materials Research, Part B Journal of Controlled Release Journal of Materials Science: Materials in Medicine Journal of Nanobiotechnology


Journal of Orthopaedic Research Journal of Periodontology Journal of Tissue Engineering Journal of Tissue Engineering and Regenerative Medicine Langmuir Macromolecules Materials Materials Today Medical Engineering & Physics PLoS One Proceedings of the National Academy of Sciences Recent Patents on Biomedical Engineering RSC Advances Soft Matter Stem Cell Research Stem Cell Research & Therapy Tissue Engineering, Part A Tissue Engineering, Part B: Reviews Tissue Engineering, Part C: Methods

CONSULTANTSHIPS: None

SERVICE ON NATIONAL GRANT REVIEWS PANELS, STUDY SECTIONS, ADVISORY PANELS AND COMMITTEES:

None

SERVICE ON THE UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON COMMITTEES:

2014-Pres Interfaculty Council

SERVICE ON THE UNIVERSITY OF TEXAS SCHOOL OF DENTISTRY AT HOUSTON COMMITTEES:

2014-Pres Faculty Senate President-elect, 2014-2015 2014-Pres Research Committee

SERVICE ON RICE UNIVERSITY COMMITTEES: 2009-2010 ABET Materials Preparation Assistance, Department of Bioengineering 2006-2007 Rice University Citizens’ Police Academy

Officer Assessment Panel, 2007


Cadet, 2006 2001-2005 Rice University Bioengineering Graduate Student Association

Founding Committee Member, 2001 1999-2001 Rice Graduate Apartment Council

Representative & Founding Committee Member, 1999-2001

SERVICE TO THE COMMUNITY: Rice University

2013-Pres Association of Rice Alumni, Rice University Member, Board of Directors, 2013-Pres

Student Programing and Engagement Committee, 2013-Pres Alumni Education Committee, 2013-Pres Vice-chair, Alumni Education Committee, 2014-Pres Nominations Committee, 2013-Pres Alumni Recognition Committee, 2006-2008, 2013-Pres Graduate Degree Alumni Committee, 2006-Pres Chair, Graduate Degree Alumni Committee, 2008 2009-Pres McMurty College, Rice University Faculty Associate, 2009-2014 Community Associate, 2014-Pres

Professional Societies

Advisory Boards 2010 International Advisory Board, 16th International Biomedical Science & Technology

Symposium (BIOMED 2010), Beşiktaş, İstanbul, Turkey 2010 Scientific Advisory Board, Annual Meeting of the Tissue Engineering and

Regenerative Medicine International Society (TERMIS) North America Chapter, Orlando, Florida

Faculty Mentor 2012 Invited Faculty Mentor, Tissue Engineering and Regenerative Medicine

International Society (TERMIS) World Congress, Student-Mentor Meet, Vienna, Austria

2010 Invited Faculty Mentor, Annual Meeting of the Tissue Engineering and Regenerative Medicine International Society (TERMIS) North America Chapter, Student and Young Investigator Section Activities, Orlando, Florida

2011 Invited Faculty Mentor, Annual Meeting of the Tissue Engineering and Regenerative Medicine International Society (TERMIS) North America Chapter, Student-Meet Mentor Luncheon, Houston, Texas

Organization and Chairing of Sessions and Symposia 2012 Symposium Organizer, World Biomaterials Congress, Chengdu, China 2012 Session Co-Chair, Tissue Engineering and Regenerative Medicine International

Society (TERMIS) World Congress, Vienna, Austria


2012 Session Co-Chair, World Biomaterials Congress, Chengdu, China 2011 Session Chair, Bone-Tec 2011 International Bone Tissue Engineering Congress,

Hannover, Germany 2011 Session Co-Chair, 4th International Conference on Tissue Engineering, Crete,

Greece 2010 Session Co-Chair, Annual Meeting of the Biomedical Engineering Society,

Austin, Texas 2010 Session Co-Chair, 16th International Biomedical Science & Technology

Symposium (BIOMED 2010), Beşiktaş, İstanbul, Turkey 2009 Session Co-Chair, 26th Annual Houston Conference on Biomedical Engineering

Research, Houston, Texas 2008 Session Co-Chair, 3rd International Conference on Tissue Engineering, Rhodes,

Greece Abstract Reviewer 2013 Abstract Reviewer, Meeting of the Tissue Engineering and Regenerative

Medicine International Society (TERMIS) Americas Chapter Meeting, Atlanta, Georgia

2013 Abstract Reviewer, Annual Meeting of the Biomedical Engineering Society, Seattle, Washington

2012 Abstract Reviewer, Society For Biomaterials Fall Symposium, New Orleans, Louisiana

2012 Abstract Reviewer, Tissue Engineering and Regenerative Medicine International Society (TERMIS) World Congress, Vienna, Austria

2012 Abstract Reviewer, World Biomaterials Congress, Chengdu, China 2011 Abstract Reviewer, Meeting of the Tissue Engineering and Regenerative

Medicine International Society (TERMIS) North America Chapter Meeting, Houston, Texas

2011 Abstract Reviewer, Annual Meeting of the Society For Biomaterials, Orlando, Florida

2010 Abstract Reviewer, Annual Meeting of the Biomedical Engineering Society, Austin, Texas

2010 Abstract Reviewer, Annual Meeting of the Society For Biomaterials, Seattle, Washington

2009 Abstract Reviewer, Annual Meeting of the Society For Biomaterials, San Antonio, Texas

Poster Judge 2011 Poster Judge, Annual Meeting of the Tissue Engineering and Regenerative

Medicine International Society (TERMIS) North America Chapter, Houston, Texas

2010 Poster Judge, Annual Meeting of the Tissue Engineering and Regenerative Medicine International Society (TERMIS) North America Chapter, Orlando, Florida

Chemical Educational Foundation

2009-2014 Reviewer of Study Guide and Exam Questions for the Texas State and National

You Be the Chemist Challenges


2014 Speaking Judge, National You Be the Chemist Challenge, Kimmel Center, Philadelphia, PA

2014 Speaking Judge, Texas State You Be the Chemist Challenge, Houston Museum of Natural Science, Houston, TX

2014 Speaking Judge, Houston Local You Be the Chemist Challenge, Houston Food Bank, Houston, TX


2013 Speaking Judge, Texas State You Be the Chemist Challenge, University of Houston, Houston, TX

2013 Speaking Judge, Houston Local You Be the Chemist Challenge, It’z, Houston, TX


2012 Speaking Judge, Texas State You Be the Chemist Challenge, Houston Museum of Natural Science, Houston, TX

2011 Speaking Judge, National You Be the Chemist Challenge, National Constitution Center, Philadelphia, PA

2011 Judge, Houston Local You Be the Chemist Challenge, It’z, Houston, TX 2010 Speaking Judge, Texas State You Be the Chemist Challenge, Space Center

Houston, Houston, TX 2010 Judge, National You Be the Chemist Challenge, National Constitution Center,

Philadelphia, PA 2009 Speaking Judge, National You Be the Chemist Challenge, National Constitution

Center, Philadelphia, PA 2009 Speaking Judge, Texas State You Be the Chemist Challenge, Space Center

Houston, Houston, TX

SPONSORSHIP OF UNDERGRADUATE STUDENTS:

Rice University

John W. Baker, 2002 Stephanie K. Seidlits, 2002-2003 Todd T. Tomson, 2002 Erin D. Jerkins, 2004-2005 Mimi W. Zhang, 2008 Andy Chang, 2008-2009 Georgia K. Lagoudas, 2009

National Science Foundation Graduate Fellowship, 2012 Dai Zhang, 2009-2010

Rice University Century Scholar, 2009 Denny Lehman, 2009-2011 Benjamin Y. Lu, 2009-2011

Research Excellence Award, Rice Engineering Alumni, 2011 Outstanding Bioengineering Junior Award, Rice University, 2010 Honorable Mention Award for Outstanding Student Presentation, American Association for the Advancement of Science – Southwestern and Rocky Mountain Division Annual Meeting, 2010 George R. Brown Undergraduate Research Intern, Rice University, 2009 HHMI International Undergraduate Research Program Nominee, 2009


Kevin R. Perkins, 2009-2012 Stephanie N. Tzouanas, 2009-2014

Outstanding Junior Award, School of Engineering, Rice Engineering Alumni, 2013 Texas Society of Professional Engineers Outstanding Student Award, 2013 Outstanding Bioengineering Junior Award, Rice University, 2013 Goldwater Scholar, 2012 Research Excellence Award, Rice Engineering Alumni, 2012 Century Scholar, 2010

Joseph Yu, 2009-2013 Chia-Ye Chu, 2010-2014

Century Scholar, 2010 Mengwei Ni, 2010-2014

Century Scholar, 2010 Mallory T. Pierpoint, 2010-2011 Austin K. Williams, 2010-2012 Kylie E. Witherel, 2010-2011 Aline Lueckgen, 2011-2012 Sachin Allahabadi, 2011-2012 Don Gwak, 2011-2013 Olivia Hu, 2011-2014 Sophie Petrichenko, 2011-2012

SPONSORSHIP OF CANDIDATES FOR POSTGRADUATE DEGREE:

Rice University Richard A. Thibault, Ph.D. Candidate, 2006-2012

Ruth L. Kirschstein National Research Service Award, National Institutes of Health, 2008-2012 Emily L. Burdett, M.S. Candidate, 2007-2012

National Institutes of Health Biotechnology Program Trainee, 2008-2010 Paschalia M. Mountziaris, Ph.D. Candidate, 2007-2011

Graduate Student Award for Outstanding Research, Society For Biomaterials, 2012 Mary F.D. Morse Graduate Fellowship, Institute of Biosciences and Bioengineering, Rice University, 2010 National Institutes of Health Biotechnology Program Trainee, 2010-2011 Best Poster Award for Superior Presentation, Annual Research Conference of W.M. Keck Center for Interdisciplinary Bioscience Training, 2009 Edgar O’Rear Travel Grant, Institute of Biosciences and Bioengineering, Rice University, 2009 Student Travel Achievement Recognition, Society For Biomaterials, 2009 National Institutes of Health Nanobiology Program Trainee, 2008-2010

Allan M. Henslee, Ph.D. Candidate, 2008-2013 Erica J. Levorson, Ph.D. Candidate, 2008-2013

National Institutes of Health Biotechnology Program Trainee, 2009 Clark J. Needham, Ph.D. Candidate, 2008-2014

Robert L. Patten Award, Rice University, 2012 Patrick P. Spicer, Ph.D. Candidate, 2008-2012

Baylor College of Medicine Medical Scientist Training Program Publication Award, 2013 Rebecca L. Dahlin, Ph.D. Candidate, 2009-2014

P.E.O. Scholar Award, 2012-2013 Lucas A. Kinard, Ph.D. Candidate, 2009-2014


President’s Summer Fellowship, Rice University, 2013 Travel Award, Advanced Technology Applications for Combat Casualty Care Meeting, 2010 National Science Foundation Graduate Fellowship, 2009-2014

Brendan M. Watson, Ph.D. Candidate, 2009-2014 National Institutes of Health Nanobiology Program Trainee, 2010

Eliza L.S. Fong, Ph.D. Candidate, 2010-2014 Johnny Lam, Ph.D. Candidate, 2010-2014 Steven Lu, Ph.D. Candidate, 2010-2014 Tiffany N. Vo, Ph.D. Candidate, 2010-2014

Edgar O’Rear Travel Grant, Institute of Biosciences and Bioengineering, Rice University, 2012 National Institutes of Health Baylor’s Scientific Training Program for Dental Academic Researchers: B-Stars Trainee, 2011

Marco Santoro, Ph.D. Candidate, 2011-2014 Jordan E. Trachtenberg, Ph.D. Candidate, 2011-2014

National Science Foundation Graduate Fellowship, 2011-2014 Kelsea M. Hubka, Ph.D. Candidate, 2012-2014 Esther Lee, Ph.D. Candidate, 2012-2014

National Science Foundation Graduate Fellowship, 2012-2014 Sarita Shah, Ph.D. Candidate, 2012-2014 Alex Tatara, Ph.D. Candidate, 2012-2014

SPONSORSHIP OF POSTDOCTORAL FELLOWS:

Rice University

Meng Shi, Ph.D. (University of Toronto, 2008), 2008-2011 Milind Singh, Ph.D. (University of Kansas, 2008), 2008-2010 Ville V. Meretoja, Ph.D. (University of Turku, 2008), 2009-2013 Diana M. Yoon, Ph.D. (University of Maryland, 2008), 2009-2011

National Institutes of Health Nanobiology Program Trainee, 2009-2010 Manitha B. Nair, Ph.D. (Sree Chitra Tirunal Institute for Medical Sciences and Technology, 2009),

2009-2010 Kyle E. Hammerick, Ph.D. (Stanford University, 2009), 2009-2011

Alliance for NanoHealth Postdoctoral Fellowship, 2009-2011 Adam Ekenseair, Ph.D. (University of Texas at Austin, 2010), 2010-2013 George E. Kapellos, Ph.D. (University of Patras, 2008), 2010 Kyobum Kim, Ph.D. (University of Maryland, 2010), 2010-2012 Limin Wang, Ph.D. (University of Kansas, 2008), 2011-2013 Julia Gershovich, Ph.D. (State Scientific Center of Russian Federation Institute for Biomedical Problems of the Russian Academy of Sciences, 2009), 2011-2012 National Space Biomedical Research Institute Postdoctoral Fellowship, 2011-2012 Yu-Chieh Chiu, Ph.D. (Illinois Institute of Technology, 2011), 2012-2013 Hajar Seyednejad, Ph.D. (Utrecth University, 2012), 2012-2013

CURRENT TEACHING RESPONSIBILITIES: Course Director, 2143DBPG1106-100: Cell/Developmental Biology Course Director, 2143DBPG1110-100: Oral Biology-Development, Structure & Function of Tissues


CURRENT GRANT SUPPORT:

National Institutes of Health FK Kasper, JA Ludwig and AG Mikos (PIs) 2014-2019 “Three-dimensional Model of Human Ewing Sarcoma” The specific aims of this project involve the leverage of tissue engineering techniques toward the development and characterization of three-dimensional models of human Ewing sarcoma. Role: PI

National Institutes of Health FK Kasper and AG Mikos (PIs) 2010-2015 “Injectable Cellular Composites for Cartilage Engineering” The specific aims of this project involve the development of injectable, bilayered, biodegradable hydrogel composites for the co-delivery of chondrogenic growth factors and mesenchymal stem cells for cartilage tissue engineering. Role: PI

PAST GRANT SUPPORT: Department of Defense AG Mikos (PI) 2014-2018* “Space Maintenance, Wound Optimization, Osseous Regeneration and Reconstruction for Craniomaxillofacial Defects” The specific aims of this project involve the development of porous poly(methylmethacrylate)-based materials releasing antibiotic(s) in a controlled manner to mitigate wound infection in osseous space maintenance applications. Role: Co-Investigator

*Participation ended 06/30/2014 upon transition to UTHealth

Department of Defense AG Mikos (PI) 2014-2018* “Development of Resorbable Calcium Phosphate for Regeneration of Cranial and Midface Bones” The specific aims of this project include the development of fully resorbable injectable calcium phosphate-based cements incorporating poly(lactic-co-glycolic acid) microspheres for clinical application in cranial and midface bones. Role: Co-Investigator *Participation ended 06/30/2014 upon transition to UTHealth

Department of Defense FK Kasper and AG Mikos (PIs) 2008-2013 “Antibiotic Releasing Space Maintainer and Prefabricated Vascularized Bone Flap” The specific aims of this project involve investigations to decrease the complications and infections associated with large bony reconstructions in injured military personnel through initial implantation of an antibiotic releasing space maintainer followed by implantation of a vascularized bone flap. Role: PI Defense Adv. Res. Proj. Agency FK Kasper and AG Mikos (PIs) 2008-2010 “BioNanoScaffolds (BNS) for Post-traumatic Osteoregeneration” The specific aims of this project involve the development of a fracture putty material made of poly(propylene fumarate) and biodegradable nanoporous silicon enclosures. Role: PI

PUBLICATIONS:


A. Abstracts

1. Mikos AG and Kasper FK, “Biomaterials for Tissue Engineering,” Abstr. Intern. Confer.

Biomed. Eng., Abstract PL1 (December 2013). 2. Mikos AG, Wong ME and Kasper FK, “Leveraging Biomaterials in Translational Strategies for

Craniofacial Bone Repair,” Abstr. Intern. Confer. Biomed. Eng., Abstract SYM-01:1 (December 2013).

3. Ekenseair AK, Tzouanas SN, Vo TN, Spicer PP, Watson BM, Mountziaris PM, Kasper FK and

Mikos AG, “Spontaneous Mineralization of Hydrophobic Hydrogels for Craniofacial Bone Tissue Regeneration,” Abstr. AIChE Meeting, Abstract 42d (November 2013).

4. Watson BM, Kasper FK, Engel PS and Mikos AG, “Synthesis and Characterization of Novel, In

Situ Cross-linkable, Biodegradable, Thermoresponsive Hydrogels for Bone Tissue Engineering,” Abstr. AIChE Meeting, Abstract 489a (November 2013).

5. Lalwani G, Henslee AM, Farshid B, Lin L, Kasper FK, Qin Y-X, Mikos AG and Sitharaman B,

“Two Dimensional Carbon and Inorganic Nanostructures Reinforced Biodegradable Polymeric Nanocomposites for Bone Tissue Engineering,” Abstr. BMES Meeting, Abstract P-Fri-A-66 (September 2013).

6. Wang H, Kinard LA, Wang L, Liu J, Wang Y, Liu Z, Kasper FK, Mikos AG and Wang C, “OPF

Hydrogel Prevents Adverse Remodeling after Myocardial Infarction by Inhibiting Serum Response Factor Mediated Myofibroblast Transformation in Cardiac Fibroblasts and its Application in Heart Regeneration,” Abstr. Intern. Conf. Regener. Biomed. Mater., Abstract 110 (June 2013).

7. Lam J, Dahlin RL, Lu S, Tabata Y, Mikos AG and Kasper FK, “Articular Chondrocyte and

Mesenchymal Stem Cell Co-cultures in Hydrogels for Osteochondral Tissue Engineering,” Abstr. TERMIS-Americas Ann. Confer. Exp., Abstract Online (November 2013).

8. Lam J, Lu S, Mikos AG and Kasper FK, “Chondrogenic and Osteogenic Pre-differentiation of

Mesenchymal Stem Cells for Osteochondral Tissue Engineering Using Bilayered Hydrogels,” Abstr. BMES Meeting, Abstract P-Th-B-282 (September 2013).

9. Kinard LA, Kasper FK and Mikos AG, “Oligo(poly(ethylene glycol) fumarate) as a Synthetic

Hydrogel Carrier for Demineralized Bone Matrix,” Abstr. TERMIS-Americas Ann. Confer. Exp., Abstract Online (November 2013).

10. Santoro M, Lamhamedi-Cherradi S-E, Kasper FK, Ludwig JA and Mikos AG, “In Vitro Tumor

Model Generated Using a Flow Perfusion Bioreactor,” Abstr. BMES Meeting, Abstract OP-Sat-1-2F (September 2013).

11. Dahlin RL, Meretoja VV, Ni M, Kasper FK and Mikos AG, “Enhancing the Chondrogenic

Phenotype of Articular Chondrocytes in Flow Perfusion,” Abstr. TERMIS-Americas Ann. Confer. Exp., Abstract Online (November 2013).


12. Meretoja VV, Dahlin RL, Wright S, Ni M, Kasper FK and Mikos AG, “Effect of Chondrocyte Dedifferentiation on 3D Co-cultures with Mesenchymal Stem Cells,” Abstr. BMES Meeting, Abstract P-Th-B-266 (September 2013).

13. Dahlin R, Meretoja V, Ni M, Kasper FK and Mikos AG, “Flow Perfusion Co-culture of Articular Chondrocytes and Mesenchymal Stem Cells,” Abstr. TERMIS World Congr., 3, Abstract 56.P07 (September 2012).

14. Kim K, Lam J, Lu S, Tabata Y, Mikos AG and Kasper FK, “Dual Growth Factor Delivery from Bilayered Composite Hydrogels for Osteochondral Tissue Repair in a Rabbit Model,” Abstr. TERMIS World Congr., 3, Abstract 08.P30 (September 2012).

15. Spicer PP, Henslee AM, Nawab A, Demian N, Kasper FK, Mikos AG and Wong ME, “Porous Polymethylmethacrylate Fabricated Intraoperatively as a Mandibular Space Maintainer Post Tumor Resection: A Case Series,” Abstr. TERMIS World Congr., 3, Abstract 03.P22 (September 2012).

16. Kinard LA, Chu C, Kasper FK and Mikos AG, “Controlled Delivery of rhBMP-2 from OPF Hydrogel Composites for Bone Tissue Engineering,” Abstr. TERMIS World Congr., 3, Abstract 54.02 (September 2012).

17. Kim K, Lu S, Lam J, Tabata Y, Mikos AG and Kasper FK, “Delivery of Growth Factors and Mesenchymal Stem Cells Using Bilayered Hydrogels for Osteochondral Tissue Regeneration,” Abstr. Intern. Conf. Nanotechn. Bio-Med. Interf., 2, Abstract 130 (February 2012).

18. Kasper FK and Mikos AG, “Harnessing Nanotechnology in Approaches for Tissue Engineering,” Abstr. Intern. Conf. Nanotechn. Bio-Med. Interf., 2, Abstract 14 (February 2012).

19. Spicer PP, Shi M, Demian N, Wong ME, Kasper FK and Mikos AG, “Characterization of Poly(methylmethacrylate)/Gelatin Constructs for Osseous Space Maintenance and Antibiotic Delivery,” Abstr. TERMIS-North America Ann. Confer. Exp., Abstract 383 (December 2011).

20. Yoon DM, Henslee AM, Lu BY, Arango AA, Marruffo LP, Seng LJ, Anver TD, Ather H, Demian N, Wong ME, Kasper FK and Mikos AG, “Characterizing an Injectable Synthetic Biodegradable Polymer to Mechanically Stabilize Mandibular Defects,” Abstr. TERMIS-North America Ann. Confer. Exp., Abstract 312 (December 2011).

21. Henslee AM, Gwak D-H, Wong ME, Mikos AG and Kasper FK, “Development of a Biodegradable Bone Cement for Craniofacial Applications,” Abstr. TERMIS-North America Ann. Confer. Exp., Abstract 301 (December 2011).

22. Appel AA, Larson J, Somo S, Anastasio MA, Spicer PP, Kasper FK, Mikos AG and Brey EM, “Three Dimensional Quantitative Imaging of Biomaterials in Engineered Tissues with X-ray Phase Contrast,” Abstr. TERMIS-North America Ann. Confer. Exp., Abstract 246 (December 2011).

23. Kim K, Lu S, Lam J, Tabata Y, Mikos AG and Kasper FK, “Optimizing Encapsulation Densities of Cell Populations in Bilayered Hydrogels for Osteochondral Tissue Engineering,” Abstr. TERMIS-North America Ann. Confer. Exp., Abstract 225 (December 2011).


24. Kim K, Lam J, Lu S, Tabata Y, Mikos AG and Kasper FK, “Dual Growth Factor Release from Bilayered Oligo(poly(ethylene glycol) fumarate) Hydrogels,” Abstr. TERMIS-North America Ann. Confer. Exp., Abstract 224 (December 2011).

25. Dahlin RL, Meretoja VV, Kasper FK and Mikos AG, “Testing of a High Throughput Flow Perfusion Bioreactor for Osteochondral Tissue Engineering,” Abstr. TERMIS-North America Ann. Confer. Exp., Abstract 180 (December 2011).

26. Meretoja VV, Dahlin RL, Kasper FK and Mikos AG, “Enhanced Chondrogenesis in Mesenchymal Stem Cell Cultures Supplemented with Articular Chondrocytes,” Abstr. TERMIS-North America Ann. Confer. Exp., Abstract 147 (December 2011).

27. Vo TN, Ekenseair AK, Boere KWM, Kasper FK and Mikos AG, “Injectable PNiPAAm-based Scaffolds with Tunable LCST for Craniofacial Bone Regeneration,” Abstr. TERMIS-North America Ann. Confer. Exp., Abstract 144 (December 2011).

28. Thibault RA, Kasper FK and Mikos AG, “Protein and Mineral Composition of an Extracellular Matrix Scaffold for Osteogenic Differentiation of Bone Marrow Stromal Cells,” Abstr. AIChE Meeting, Abstract 567f (October 2011).

29. Ekenseair AK, Zuiker N, Kasper FK and Mikos AG, “Optimization of Thermogelling, Injectable Scaffolds for Craniofacial Tissue Regeneration,” Abstr. AIChE Meeting, Abstract 275f (October 2011).

30. Ekenseair AK, Boere KWM, Kasper FK and Mikos AG, “A Novel Epoxy-based, Injectable Hydrogel Scaffold for Tissue Regeneration,” Abstr. AIChE Meeting, Abstract 74h (October 2011).

31. Hammerick KE, Kasper FK and Mikos AG, “Nanostructured Scaffolds for Regulating Osteogenic Differentiation of Induced Pluripotent Stem Cells,” Abstr. BMES Meeting, Abstract Sat-2-9-F (October 2011).

32. Needham CJ, Chew S, Williams AK, Kasper FK and Mikos AG, “The Effect of Primary Amines, Overall Charge, and Ligand Targeting on the Effectiveness of Poly(ethylenimine)-hyaluronic Acid Conjugates as Gene Therapy Agents,” Abstr. BMES Meeting, Abstract PS-Thurs-B-197 (October 2011).

33. Mountziaris PM, Tzouanas SN, Mikos AG and Kasper FK, “Harnessing Inflammation in Strategies for Bone Tissue Engineering,” Aegean Confer. Ser., 55, Abstract 91 (June 2011).

34. Burdett E, Kasper FK, Mikos AG and Ludwig JA, “Development of a 3D Tissue Engineered Cancer Model for Drug Screening,” Aegean Confer. Ser., 55, Abstract 65 (June 2011).

35. Spicer PP, Shi M, Kretlow JD, Young S, Demian N, Jansen JA, Wong ME, Kasper FK and Mikos AG, “Antibiotic-releasing Porous Poly(methylmethacrylate) Space Maintainers for Craniofacial Tissue Engineering,” Aegean Confer. Ser., 55, Abstract 50 (June 2011).

36. Spicer PP, Kretlow JD, Henslee AM, Shi M, Young S, Demian N, Jansen JA, Wong MEK, Kasper FK and Mikos AG, “In Situ Formation of Porous Poly(methyl methacrylate) Space Maintainers for Craniofacial Complex Regeneration,” Abstr. TERMIS-North America Ann. Confer. Exp., Abstract 1331 (December 2010).


37. Yoon DM, Henslee AM, Arango AA, Marruffo LP, Nair MB, Anver TD, Ather H, Demian N,

Wong MEK, Kasper FK and Mikos AG, “Developing In-situ Crosslinkable Scaffold to Mechanically Stabilize Mandibular Defects,” Abstr. TERMIS-North America Ann. Confer. Exp., Abstract 1314 (December 2010).

38. Meretoja VV, Dahlin RL, Kasper FK and Mikos AG, “Enhanced Chondrogenesis of Mesenchymal Stem Cells under Flow Perfusion Conditions,” Abstr. TERMIS-North America Ann. Confer. Exp., Abstract 291 (December 2010).

39. Klouda L, Perkins KR, Kasper FK and Mikos AG, “Fabrication and Characterization of Thermally Responsive, In Situ Crosslinkable Hydrogels Based on Poly(N-isopropylacrylamide),” Abstr. AIChE Meeting, Abstract 513f (November 2010).

40. Buchanan R, Murphy M, Yoon DM, Henslee A, Nair M, Liu X, Kasper FK, Simmons P, Mikos AG, Ferrari M and Tasciotti E, “Trifunctional Porogens for the Development of an Injectable Putty to Treat Traumatic Bone Defects,” Abstr. BMES Meeting, Abstract OP-9-3-1E (October 2010).

41. Levorson EJ, Kasper FK and Mikos AG, “Development of a Chondrogenic Pellet Preculture System for Cartilage Tissue Engineering Applications,” Abstr. BMES Meeting, Abstract OP-9-1-15C (October 2010).

42. Yoon DM, Lu BY, Bakota EL, Kasper FK, Hartgerink JD and Mikos AG, “Exploring Multi-domain Peptides and Gelatin Microparticles as an Osteogenic Factor Delivery System,” Abstr. BMES Meeting, Abstract OP-9-1-13C (October 2010).

43. Singh M, Kasper FK and Mikos AG, “Cartilage Tissue Engineering Using Neonatal Human Dermal Fibroblasts,” Abstr. BMES Meeting, Abstract PS-9A-18-209 (October 2010).

44. Burdett E, Mikos AG, Kasper FK and Ludwig JA, “The Development of a 3D Tissue Engineered Bone Tumor Model,” Abstr. BMES Meeting, Abstract OP-8-2-16F (October 2010).

45. Mountziaris PM, Lehman ED, Kasper FK and Mikos AG, “Effect of Patterned TNF-α Delivery on In Vitro Osteogenic Differentiation of Mesenchymal Stem Cells,” Abstr. BMES Meeting, Abstract PS-8A-19-267 (October 2010).

46. Henslee A, Gwak D-H, Mikos AG and Kasper FK, “Development and Optimization of a Biodegradable Bone Cement for Clinical Applications,” Abstr. BMES Meeting, Abstract OP-7-2-9B (October 2010).

47. Kasper FK, Mountziaris PM, Tzouanas SN and Mikos AG, “Harnessing Inflammation in Strategies for Bone Tissue Engineering,” Abstr. Am. Aging Assoc. Meeting, 39, Abstract 37 (June 2010).

48. Kasper FK and Mikos AG, “Emerging Biomaterial Approaches for Bone Regeneration,” Abstr. AIChE Meeting, Abstract 282f (November 2009).

49. Liao J, Guo X, Kasper FK and Mikos AG, “Effect of a Mineralized Extracellular Matrix Scaffold Generated in Flow Perfusion on the Osteogenic Differentiation of Mesenchymal Stem Cells,” Abstr. TERMIS World Congr., 2, Abstract 1104 (August 2009).


50. Martins AM, Kasper FK, Kretlow JD, Costa-Pinto AR, Malafaya PB, Neves NM, Alves CM,

Reis RL and Mikos AG, “In Vivo Responsive Scaffolds with the Ability of In Situ Pore Formation: A Novel Strategy for Bone Tissue Engineering,” Abstr. TERMIS World Congr., 2, Abstract 1039 (August 2009).

51. Martins AM, Saraf A, Sousa RA, Kasper FK, Alves CM, Reis RL and Mikos AG, “Towards Osteogenic Differentiation of Bone Marrow Stromal Cells Cultured onto Starch/Poly(ε-caprolactone) Fiber Mesh Scaffolds: The Efficiency of Enzymes and Flow Perfusion Bioreactors,” Abstr. TERMIS World Congr., 2, Abstract 985 (August 2009).

52. Saraf A, Baggett LS, Kasper FK and Mikos AG, “Regulated Non-viral Gene Delivery from Coaxial Electrospun Fiber Mesh Scaffolds,” Abstr. TERMIS World Congr., 2, Abstract 372 (August 2009).

53. Guo X, Park H, Kasper FK and Mikos AG, “In Vitro Generation of an Osteochondral Construct Using Injectable Hydrogel Composites Encapsulating Rabbit Marrow Mesenchymal Stem Cells,” Abstr. TERMIS World Congr., 2, Abstract 158 (August 2009).

54. Shi M, Kretlow JD, Young S, Kasper FK, Wong M and Mikos AG, “Antibiotic-releasing Porous Poly(methyl methacrylate) Scaffolds for Osseous Space Maintenance and Infection Control,” Abstr. TERMIS World Congr., 2, Abstract 35 (August 2009).

55. Kretlow JD, Shi M, Young S, Kasper FK, Wong M and Mikos AG, “Porous Poly(methyl methacrylate) Implants for Osseous Space Maintenance and Promotion of Soft Tissue Healing around Craniofacial Bone Defects,” Abstr. TERMIS World Congr., 2, Abstract 7 (August 2009).

56. Shi M, Kretlow JD, Young S, Kasper FK, Wong M and Mikos AG, “Characterization of Porous Poly(methyl methacrylate) Scaffolds for Osseous Space Maintenance,” Abstr. HSEMB Confer., 26, Abstract 181 (March 2009).

57. Liao J, Kasper FK and Mikos AG, “Effect of Flow Perfusion on Osteogenic Differentiation of Mesenchymal Stem Cells Cultured on Biodegradable Microfiber Scaffolds,” Abstr. HSEMB Confer., 26, Abstract 63 (March 2009).

58. Martins AM, Saraf A, Kasper FK, Alves CM, Reis RL and Mikos AG, “Lipase Promotes Osteogenic Differentiation of Marrow Stromal Cells on SPCL Fiber Meshes under Flow Perfusion Conditions,” Abstr. TERMIS-North America Ann. Confer. Exp., Abstract 420 (December 2008).

59. Kasper FK, Thibault RA and Mikos AG, “Mineralized Extracellular Matrix Constructs Support the Osteogenic Differentiation of Mesenchymal Stem Cells In Vitro,” Abstr. AIChE Meeting, Abstract 579c (November 2008).

60. Kasper FK, Thibault RA and Mikos AG, “Mineralized Extracellular Matrix Constructs for Bone Tissue Engineering,” Abstr. Intern. Symp. Biomin., 10, Abstract F-01 (September 2008).

61. Kasper FK, Pham QP and Mikos AG, “Generation of Tissue Engineering Scaffolds with a Flow Perfusion Bioreactor,” Abstr. Intern. Bone Fluid Flow Workshop, 8, Abstract 30 (September 2007).


62. Mikos AG, Holland TA, Kasper FK and Temenoff JS, “Cell and Bioactive Factor Delivery from Injectable, Biodegradable Hydrogel Scaffolds for Tissue Engineering,” Abstr. Intern. Confer. Mater. Adv. Technol., Abstract A-10-KN8 (July 2005).

63. Jabbari E, Kasper FK and Mikos AG, “Controlled Release of Plasmid DNA from Biodegradable Oligo(poly(ethylene glycol) fumarate) Hydrogel Microspheres,” Abstr. AIChE Meeting, Abstract 305a (November 2002).

64. Mikos AG, Hedberg EL, Kasper FK and Temenoff JS, “Injectable, In Situ Crosslinkable, Biodegradable Polymers for Peptide and Gene Delivery,” Abstr. AAPS Workshop (February 2002).

B. Refereed Original Articles in Journals

1. Wang L, Lu S, Lam J, Kasper FK and Mikos AG. Fabrication of Cell-laden Macroporous Biodegradable Hydrogels with Tunable Porosities and Pore Sizes. Tissue Engineering, Part C: Methods, in press. (DOI:10.1089/ten.TEC.2014.0224)

2. Dahlin RL, Kinard LA, Lam J, Needham CJ, Lu S, Kasper FK and Mikos AG. Articular

Chondrocytes and Mesenchymal Stem Cells Seeded on Biodegradable Scaffolds for the Repair of Cartilage in a Rat Osteochondral Defect Model. Biomaterials, 35(26):7460-7469, 2014. PMCID: PMC4109803

3. Henslee AM, Shah SR, Wong ME, Mikos AG and Kasper FK. Degradable, Antibiotic

Releasing Poly(propylene fumarate)-based Constructs for Craniofacial Space Maintenance Applications. Journal of Biomedical Materials Research, Part A, in press. (DOI:10.1002/jbm.a.35288)

4. Lam J, Lu S, Lee EJ, Trachtenberg JE, Meretoja VV, Dahlin RL, van den Beucken JJ, Tabata

Y, Wong ME, Jansen JA, Mikos AG and Kasper FK. Osteochondral Defect Repair Using Bilayered Hydrogels Encapsulating Both Chondrogenically and Osteogenically Pre-differentiated Mesenchymal Stem Cells in a Rabbit Model. Osteoarthritis and Cartilage, 22(9):1291-1300, 2014. PMCID: PMC4150851

5. Lu S, Lam J, Trachtenberg J, Lee E, Seyednejad H, Tabata Y, Wong ME, van den Beucken

JJ, Jansen JA, Mikos AG and Kasper FK. Dual Growth Factor Delivery from Bilayered, Biodegradable Hydrogel Composites for Spatially-guided Osteochondral Tissue Repair. Biomaterials, 35(31):8829-8839, 2014. NIHMSID: 615251

6. Needham CJ, Shah SR, Dahlin RL, Kinard LA, Lam J, Watson BM, Lu S, Kasper FK and

Mikos AG. Osteochondral Tissue Regeneration through Polymeric Delivery of DNA Encoding for the SOX Trio and RUNX2. Acta Biomaterialia, 10(10):4103-4112, 2014.

7. Tatara AM, Shah SR, Sotoudeh M, Henslee AM, Wong ME, Ratcliffe A, Kasper FK and Mikos

AG. Effects of Electron Beam Sterilization on Mechanical Properties of a Porous Polymethylmethacrylate Space Maintenance Device. Journal of Medical Devices, submitted.

8. Lam J, Lu S, Kasper FK and Mikos AG. Strategies for Controlled Delivery of Biologics for

Cartilage Repair. Advanced Drug Delivery Reviews, in press. (DOI:10.1016/j.addr.2014.06.006)


9. Shah SR, Werlang CA, Kasper FK and Mikos AG. Applications of Statins in Bone Tissue

Engineering. National Science Review, in press. (DOI:10.1093/nsr/nwu028) 10. Kinard LA, Dahlin RL, Lam J, Lu S, Lee EJ, Kasper FK and Mikos AG. Synthetic

Biodegradable Hydrogel Delivery of Demineralized Bone Matrix for Bone Augmentation in a Rat Model. Acta Biomaterialia, 10(11):4574-4582, 2014.

11. Henslee AM, Yoon DM, Lu BY, Yu J, Arango AA, Marruffo LP, Seng L, Anver TD, Ather H,

Nair MB, Piper SO, Demian N, Wong ME, Kasper FK and Mikos AG. Characterization of an Injectable, Degradable Polymer for Mechanical Stabilization of Mandibular Fractures. Journal of Biomedical Materials Research, Part B: Applied Biomaterials, in press. (DOI:10.1002/jbm.b.33216)

12. Hubka KM, Dahlin RL, Meretoja VV, Kasper FK and Mikos AG. Enhancing Chondrogenic

Phenotype for Cartilage Tissue Engineering: Monoculture and Co-culture of Articular Chondrocytes and Mesenchymal Stem Cells. Tissue Engineering, Part B: Reviews, in press. (DOI: 10.1089/ten.teb.2014.0034)

13. Shah SR, Henslee AM, Spicer PP, Yokota S, Petrichenko S, Allahabadi S, Bennett GN, Wong

ME, Kasper FK and Mikos AG. Effects of Antibiotic Physicochemical Properties on Their Release Kinetics from Biodegradable Polymer Microparticles. Pharmaceutical Research, 31(12):3379-3389, 2014.

14. Watson BM, Kasper FK, Engel PS and Mikos AG. Synthesis and Characterization of

Injectable, Biodegradable, Phosphate-containing, Chemically Cross-linkable, Thermoresponsive Macromers for Bone Tissue Engineering. Biomacromolecules, 15(5):1788-1796, 2014. PMCID: PMC4025585

15. Wang H, Kinard LA, Wang Y, Wang L, Yin Y, Kasper FK, Liu J, Duan C, Li D, Mikos AG and

Wang C. Prevention of Myocardial Infarction-related Injury and Improved Myocardial Repair through Fumaric Acid Releasing Biodegradable Hydrogel. Advanced Functional Materials, submitted.

16. Dahlin RL, Meretoja VV, Ni M, Kasper FK and Mikos AG. Chondrogenic Phenotype of

Articular Chondrocytes in Monoculture and Co-culture with Mesenchymal Stem Cells in Flow Perfusion. Tissue Engineering, Part A, in press. (DOI:10.1089/ten.tea.2014.0107)

17. Henslee AM, Spicer PP, Shah SR, Tatara AM, Kasper FK, Mikos AG and Wong ME. Use of

Porous Space Maintainers in Staged Mandibular Reconstruction. Oral & Maxillofacial Surgery Clinics of North America, 26(2):143-149, 2014.

18. Trachtenberg JE, Mountziaris PM, Miller JS, Wettergreen M, Kasper FK and Mikos AG.

Open-source Three-dimensional Printing of Biodegradable Polymer Scaffolds for Tissue Engineering. Journal of Biomedical Materials Research, Part A, 102(12):4326-4335, 2014.

19. Tzouanas SN, Ekenseair AK, Kasper FK and Mikos AG. Mesenchymal Stem Cell and Gelatin

Microparticle Encapsulation in Thermally and Chemically Gelling Injectable Hydrogels for Tissue Engineering. Journal of Biomedical Materials Research, Part A, 102(5):1222-1230, 2014. PMCID: PMC3966975


20. Levorson EJ, Santoro M, Kasper FK and Mikos AG. Direct and Indirect Co-culture of Chondrocytes and Mesenchymal Stem Cells for the Generation of Polymer/Extracellular Matrix Hybrid Constructs. Acta Biomaterialia, 10(5):1824-1835, 2014. PMCID: PMC3976699

21. Watson BM, Kasper FK and Mikos AG. Phosphorous-containing Polymers for Regenerative

Medicine. Biomedical Materials, 9(2):025014, 2014. PMCID: PMC4005627 22. Vo TN, Ekenseair AK, Kasper FK and Mikos AG. Synthesis, Physicochemical

Characterization, and Cytocompatibility of Bioresorbable, Dual-gelling Injectable Hydrogels. Biomacromolecules, 15(1):132-142, 2014. PMCID: PMC3916782

23. Meretoja VV, Dahlin RL, Wright S, Kasper FK and Mikos AG. Articular Chondrocyte

Redifferentiation in 3D Co-cultures with Mesenchymal Stem Cells. Tissue Engineering, Part C: Methods, 20(6):514-523, 2014. PMCID: PMC4025602

24. Lam J, Lu S, Meretoja VV, Tabata Y, Mikos AG and Kasper FK. Generation of Osteochondral

Tissue Constructs with Chondrogenically and Osteogenically Pre-differentiated Mesenchymal Stem Cells Encapsulated in Bilayered Hydrogels. Acta Biomaterialia, 10(3):1112-1123, 2014. PMCID: PMC3924599

25. Lam J, Kim K, Lu S, Tabata Y, Scott DW, Mikos AG and Kasper FK. A Factorial Analysis of

the Combined Effects of Hydrogel Fabrication Parameters on the In Vitro Swelling and Degradation of Oligo(poly(ethylene glycol) fumarate) Hydrogels. Journal of Biomedical Materials Research, Part A, 102(10):3477-3487, 2014. PMCID: PMC4012001

26. Levorson EJ, Mountziaris PM, Hu O, Kasper FK and Mikos AG. Cell-derived

Polymer/Extracellular Matrix Composite Scaffolds for Cartilage Regeneration, Part 1: Investigation of Co-cultures and Seeding Densities for Improved Extracellular Matrix Deposition. Tissue Engineering, Part C: Methods, 20(4):340-357, 2014. PMCID: PMC3968878

27. Levorson EJ, Hu O, Mountziaris PM, Kasper FK and Mikos AG. Cell-derived

Polymer/Extracellular Matrix Composite Scaffolds for Cartilage Regeneration, Part 2: Construct Devitalization and Determination of Chondroinductive Capacity. Tissue Engineering, Part C: Methods, 20(4):358-372, 2014. PMCID: PMC3968877

28. Fong EL, Santoro M, Farach-Carson MC, Kasper FK and Mikos AG. Tissue Engineering

Perfusable Cancer Models. Current Opinion in Chemical Engineering, 3:112-117, 2014. PMCID: PMC3949682

29. Kinard LA, Dahlin RL, Henslee AM, Spicer PP, Chu CY, Tabata Y, van den Beucken JJ,

Jansen JA, Young S, Wong ME, Kasper FK and Mikos AG. Tissue Response to Composite Hydrogels for Vertical Bone Augmentation in the Rat. Journal of Biomedical Materials Research, Part A, 102(7):2079-2088, 2014.

30. Dahlin RL, Gershovich JG, Kasper FK and Mikos AG. Flow Perfusion Co-culture of Human

Mesenchymal Stem Cells and Endothelial Cells on Biodegradable Polymer Scaffolds. Annals of Biomedical Engineering, 42(7):1381-1390, 2014. PMCID: PMC3849322

31. Lee EJ, Kasper FK and Mikos AG. Biomaterials for Tissue Engineering. Annals of Biomedical

Engineering, 42(2):323-337, 2014. PMCID: PMC3844045


32. Needham CJ, Shah SR, Mountziaris PM, Kasper FK and Mikos AG. Modulation of Polyplex Release from Biodegradable Microparticles through Poly(ethylenimine) Modification and Varying Loading Concentration. Pharmaceutical Research, 31(1):77-85, 2014.

33. Shah SR, Kasper FK and Mikos AG. Perspectives on the Prevention and Treatment of

Infection for Tissue Engineering Applications. Chinese Science Bulletin, 58:4337-4341, 2013. 34. Ma J, Yang F, Both SK, Kersten-Niessen M, Bongio M, Pan J, Cui FZ, Kasper FK, Mikos AG,

Jansen JA and van den Beucken JJ. Comparison of Cell-loading Methods in Hydrogel Systems, Journal of Biomedical Materials Research, Part A, 102(4):935-946, 2014.

35. Dahlin RL, Ni M, Meretoja VV, Kasper FK and Mikos AG. TGF-β3-induced Chondrogenesis in

Co-cultures of Chondrocytes and Mesenchymal Stem Cells on Biodegradable Scaffolds. Biomaterials, 35(1):123-132, 2014. PMCID: PMC3844679

36. Trachtenberg JE, Mountziaris PM, Kasper FK and Mikos AG. Fiber-based Composite Tissue

Engineering Scaffolds for Drug Delivery. Israel Journal of Chemistry, 53:646-654, 2013. 37. Bongio M, Nejadnik MR, Kasper FK, Mikos AG, Jansen JA, Leeuwenburgh SC and van den

Beucken JJ. Development of an In Vitro Confinement Test to Predict the Clinical Handling of Polymer-based Injectable Bone Substitutes. Polymer Testing, 32:1379-1384, 2013.

38. Spicer PP, Shah SR, Henslee AM, Watson BM, Kinard LA, Kretlow JD, Bevil K, Kattchee L,

Bennett GN, Demian N, Mende K, Murray CK, Jansen JA, Wong ME, Mikos AG and Kasper FK. Evaluation of Antibiotic Releasing Porous Polymethylmethacrylate Space Maintainers in an Infected Composite Tissue Defect Model. Acta Biomaterialia, 9(11):8832-8839, 2013.

39. Gershovich JG, Dahlin RL, Kasper FK and Mikos AG. Enhanced Osteogenesis in Cocultures

with Human Mesenchymal Stem Cells and Endothelial Cells on Polymeric Microfiber Scaffolds. Tissue Engineering, Part A, 19(23-24):2565-2576, 2013. PMCID: PMC3856931

40. Lalwani G, Henslee AM, Farshid B, Parmar P, Lin L, Qin YX, Kasper FK, Mikos AG and

Sitharaman B. Tungsten Disulfide Nanotubes Reinforced Biodegradable Polymers for Bone Tissue Engineering. Acta Biomaterialia, 9(9):8365-8373, 2013. PMCID: PMC3732565

41. Shah SR, Tatara AM, D'Souza RN, Mikos AG and Kasper FK. Old and New: Evolving

Strategies for Preventing Biofilm on Implantable Materials. Materials Today, 16:177-182, 2013.

42. Mountziaris PM, Lehman ED, Mountziaris I, Sing DC, Kasper FK and Mikos AG. Effect of

Temporally Patterned TNF-α Delivery on In Vitro Osteogenic Differentiation of Mesenchymal Stem Cells Cultured on Biodegradable Polymer Scaffolds. Journal of Biomaterials Science: Polymer Edition, 24(15):1794-1813, 2013. PMCID: PMC3773264

43. Kinard LA, Chu CY, Tabata Y, Kasper FK and Mikos AG. Bone Morphogenetic Protein-2

Release from Composite Hydrogels of Oligo(poly(ethylene glycol) fumarate) and Gelatin. Pharmaceutical Research, 30(9):2332-2343, 2013.

44. Bongio M, Nejadnik MR, Birgani ZT, Habibovic P, Kinard LA, Kasper FK, Mikos AG, Jansen

JA, Leeuwenburgh SC and van den Beucken JJ. In Vitro and In Vivo Enzyme-mediated


Biomineralization of Oligo(poly(ethylene glycol) fumarate) Hydrogels. Macromolecular Bioscience, 13(6):777-788, 2013.

45. Wang L, Yoon DM, Spicer PP, Henslee AM, Scott DW, Wong ME, Kasper FK and Mikos AG.

Characterization of Porous Polymethylmethacrylate Space Maintainers for Craniofacial Reconstruction. Journal of Biomedical Materials Research, Part B: Applied Biomaterials, 101(5):813-825, 2013.

46. Dahlin RL, Meretoja VV, Ni M, Kasper FK and Mikos AG. Combination of Hypoxia and Flow

Perfusion Culture Modulates Proliferation and Gene Expression of Bovine Articular Chondrocytes on Porous Polymer Scaffolds. AIChE Journal, 59:3158-3166, 2013.

47. Fong EL, Lamhamedi-Cherradi SE, Burdett E, Ramamoorthy V, Lazar AJ, Kasper FK,

Farach-Carson MC, Vishwamitra D, Demicco EG, Menegaz BA, Amin HM, Mikos AG and Ludwig JA. Modeling of Ewing Sarcoma Tumors In Vitro with 3D Scaffolds. Proceedings of the National Academy of Sciences USA, 110(16):6500-6505, 2013. PMCID: PMC3631678

48. Meretoja VV, Dahlin RL, Wright S, Kasper FK and Mikos AG. The Effect of Hypoxia on the

Chondrogenic Differentiation of Co-cultured Articular Chondrocytes and Mesenchymal Stem Cells in Scaffolds. Biomaterials, 34(17):4266-4273, 2013. PMCID: PMC3610535

49. Kim K, Lam J, Lu S, Spicer PP, Lueckgen A, Tabata Y, Wong ME, Jansen JA, Mikos AG and

Kasper FK. Osteochondral Tissue Regeneration using a Bilayered Composite Hydrogel with Modulating Dual Growth Factor Release Kinetics in a Rabbit Model. Journal of Controlled Release, 168(2):166-178, 2013. PMCID: PMC3661728

50. Lalwani G, Henslee AM, Farshid B, Lin L, Kasper FK, Qin YX, Mikos AG and Sitharaman B.

Two-dimensional Nanostructure-reinforced Biodegradable Polymeric Nanocomposites for Bone Tissue Engineering. Biomacromolecules, 14(3):900-909, 2013. PMCID: PMC3601907

51. Thibault RA, Mikos AG and Kasper FK. Osteogenic Differentiation of Mesenchymal Stem

Cells on Demineralized and Devitalized Biodegradable Polymer and Extracellular Matrix Hybrid Constructs. Journal of Biomedical Materials Research, Part A, 101(5):1225-1236, 2013. PMCID: PMC3677758

52. Ekenseair AK, Kasper FK and Mikos AG. Perspectives on the Interface of Drug Delivery and

Tissue Engineering. Advanced Drug Delivery Reviews, 65(1):89-92, 2013. PMCID: PMC3548991

53. Thibault RA, Mikos AG and Kasper FK. Scaffold/Extracellular Matrix Hybrid Constructs for

Bone-tissue Engineering. Advanced Healthcare Materials, 2(1):13-24, 2013. PMCID: PMC3551448

54. Bongio M, van den Beucken JJ, Nejadnik MR, Birgani ZT, Habibovic P, Kinard LA, Kasper

FK, Mikos AG, Leeuwenburgh SC and Jansen JA. Subcutaneous Tissue Response and Osteogenic Performance of Calcium Phosphate Nanoparticle-enriched Hydrogels in the Tibial Medullary Cavity of Guinea Pigs. Acta Biomaterialia, 9(3):5464-5474, 2013.

55. Levorson EJ, Sreerekha PR, Chennazhi KP, Kasper FK, Nair SV and Mikos AG. Fabrication

and Characterization of Multiscale Electrospun Scaffolds for Cartilage Regeneration. Biomedical Materials, 8(1):014103, 2013. PMCID: PMC3857106


56. Atala A, Kasper FK and Mikos AG. Engineering Complex Tissues. Science Translational

Medicine, 4(160):160rv12, 2012. 57. Dahlin RL, Meretoja VV, Ni M, Kasper FK and Mikos AG. Design of a High-throughput Flow

Perfusion Bioreactor System for Tissue Engineering. Tissue Engineering, Part C: Methods, 18(10):817-820, 2012. PMCID: PMC3460612

58. Fong EL, Watson BM, Kasper FK and Mikos AG. Building Bridges: Leveraging

Interdisciplinary Collaborations in the Development of Biomaterials to Meet Clinical Needs. Advanced Materials, 24(36):4995-5013, 2012. PMCID: PMC3706713

59. Spicer PP, Kretlow JD, Young S, Jansen JA, Kasper FK and Mikos AG. Evaluation of Bone

Regeneration Using the Rat Critical Size Calvarial Defect. Nature Protocols, 7(10):1918-1929, 2012. PMCID: PMC3513397

60. Appel AA, Larson JC, Somo S, Zhong Z, Spicer PP, Kasper FK, Garson AB, Zysk AM, Mikos

AG, Anastasio MA and Brey EM. Imaging of Poly(α-hydroxy-ester) Scaffolds with X-ray Phase-contrast Microcomputed Tomography. Tissue Engineering, Part C: Methods, 18(11):859-865, 2012. PMCID: PMC3483049

61. Ekenseair AK, Boere KW, Tzouanas SN, Vo TN, Kasper FK and Mikos AG. Structure-

property Evaluation of Thermally and Chemically Gelling Injectable Hydrogels for Tissue Engineering. Biomacromolecules, 13(9):2821-2830, 2012. PMCID: PMC3448273

62. Mountziaris PM, Tzouanas SN, Sing DC, Kramer PR, Kasper FK and Mikos AG. Intra-

articular Controlled Release of Anti-inflammatory siRNA with Biodegradable Polymer Microparticles Ameliorates Temporomandibular Joint Inflammation. Acta Biomaterialia, 8(10):3552-3560, 2012. PMCID: PMC3429637

63. Ekenseair AK, Boere KW, Tzouanas SN, Vo TN, Kasper FK and Mikos AG. Synthesis and

Characterization of Thermally and Chemically Gelling Injectable Hydrogels for Tissue Engineering. Biomacromolecules, 13(6):1908-1915, 2012. PMCID: PMC3372601

64. Meretoja VV, Dahlin RL, Kasper FK and Mikos AG. Enhanced Chondrogenesis in Co-cultures

with Articular Chondrocytes and Mesenchymal Stem Cells. Biomaterials, 33(27):6362-6369, 2012. PMCID: PMC3392514

65. Needham CJ, Williams AK, Chew SA, Kasper FK and Mikos AG. Engineering a Polymeric

Gene Delivery Vector Based on Poly(ethylenimine) and Hyaluronic Acid. Biomacromolecules, 13(5):1429-1437, 2012. PMCID: PMC3351541

66. Vo TN, Kasper FK and Mikos AG. Strategies for Controlled Delivery of Growth Factors and

Cells for Bone Regeneration. Advanced Drug Delivery Reviews, 64(12):1292-1309, 2012. PMCID: PMC3358582

67. Henslee AM, Gwak DH, Mikos AG and Kasper FK. Development of a Biodegradable Bone

Cement for Craniofacial Applications. Journal of Biomedical Materials Research, Part A, 100(9):2252-2259, 2012. NIHMSID: 393655


68. Kinard LA, Kasper FK and Mikos AG. Synthesis of Oligo(poly(ethylene glycol) fumarate). Nature Protocols, 7(6):1219-1227, 2012. PMCID: PMC3513913

69. Spicer PP, Kretlow JD, Henslee AM, Shi M, Young S, Demian N, Jansen JA, Wong ME, Mikos

AG and Kasper FK. In Situ Formation of Porous Space Maintainers in a Composite Tissue Defect. Journal of Biomedical Materials Research, Part A, 100(4):827-833, 2012. PMCID: PMC3288442

70. Martins AM, Kretlow JD, Costa-Pinto AR, Malafaya PB, Fernandes EM, Neves NM, Alves CM,

Mikos AG, Kasper FK and Reis RL. Gradual Pore Formation in Natural Origin Scaffolds throughout Subcutaneous Implantation. Journal of Biomedical Materials Research: Part A, 100(3):599-612, 2012. PMCID: PMC3291094

71. Wang H, Liu Z, Li D, Guo X, Kasper FK, Duan C, Zhou J, Mikos AG and Wang C. Injectable

Biodegradable Hydrogels for Embryonic Stem Cell Transplantation: Improved Cardiac Remodeling and Function of Myocardial Infarction. Journal of Cellular and Molecular Medicine, 16(6):1310-1320, 2012. PMCID: PMC3227757

72. Thibault RA, Mikos AG and Kasper FK. Protein and Mineral Composition of Osteogenic

Extracellular Matrix Constructs Generated with a Flow Perfusion Bioreactor. Biomacromolecules, 12(12):4204-4212, 2011. PMCID: PMC3238915

73. Bongio M, van den Beucken JJ, Nejadnik MR, Leeuwenburgh SC, Kinard LA, Kasper FK,

Mikos AG and Jansen JA. Biomimetic Modification of Synthetic Hydrogels by Incorporation of Adhesive Peptides and Calcium Phosphate Nanoparticles: In Vitro Evaluation of Cell Behavior. European Cells and Materials Journal, 22:359-376, 2011.

74. Henslee AM, Spicer PP, Yoon DM, Nair MB, Meretoja VV, Witherel KE, Jansen JA, Mikos AG

and Kasper FK. Biodegradable Composite Scaffolds Incorporating an Intramedullary Rod and Delivering Bone Morphogenetic Protein-2 for Stabilization and Bone Regeneration in Segmental Long Bone Defects. Acta Biomaterialia, 7(10):3627-3637, 2011. PMCID: PMC3163689

75. Nair MB, Kretlow JD, Mikos AG and Kasper FK. Infection and Tissue Engineering in

Segmental Bone Defects: A Mini Review. Current Opinion in Biotechnology, 22(5):721-725, 2011. PMCID: PMC3138803

76. Singh M, Pierpoint M, Mikos AG and Kasper FK. Chondrogenic Differentiation of Neonatal

Human Dermal Fibroblasts Encapsulated in Alginate Beads with Hydrostatic Compression under Hypoxic Conditions in the Presence of Bone Morphogenetic Protein-2. Journal of Biomedical Materials Research: Part A, 98(3):412-424, 2011.

77. Liao J, Hammerick KE, Challen GA, Goodell MA, Kasper FK and Mikos AG. Investigating the

Role of Hematopoietic Stem and Progenitor Cells in Regulating the Osteogenic Differentiation of Mesenchymal Stem Cells In Vitro. Journal of Orthopaedic Research, 29(10):1544-1553, 2011. PMCID: PMC3150621

78. Shi M, Kretlow JD, Spicer PP, Tabata Y, Demian N, Wong ME, Kasper FK and Mikos AG.

Antibiotic-releasing Porous Polymethylmethacrylate/Gelatin/Antibiotic Constructs for Craniofacial Tissue Engineering. Journal of Controlled Release, 152(1):196-205, 2011. PMCID: PMC3110535


79. Dahlin RL, Kasper FK, and Mikos AG. Polymeric Nanofibers in Tissue Engineering. Tissue

Engineering, Part B: Reviews, 17(5):349-364, 2011. PMCID: PMC3179616 80. Mountziaris PM, Sing DC, Chew SA, Tzouanas SN, Lehman ED, Kasper FK and Mikos AG.

Controlled Release of Anti-inflammatory siRNA from Biodegradable Polymeric Microparticles Intended for Intra-articular Delivery to the Temporomandibular Joint. Pharmaceutical Research, 28(6):1370-1384, 2011.

81. Mountziaris PM, Spicer PP, Kasper FK and Mikos AG. Harnessing and Modulating

Inflammation in Strategies for Bone Regeneration. Tissue Engineering, Part B: Reviews, 17(6):393-402, 2011. PMCID: PMC3223017

82. Klouda L, Perkins KR, Watson BM, Hacker MC, Bryant SJ, Raphael RM, Kasper FK and

Mikos AG. Thermoresponsive, In Situ Cross-linkable Hydrogels Based on N-isopropylacrylamide: Fabrication, Characterization and Mesenchymal Stem Cell Encapsulation. Acta Biomaterialia, 7(4):1460-1467, 2011. PMCID: PMC3050091

83. Chew SA, Kretlow JD, Spicer PP, Edwards AW, Baggett LS, Tabata Y, Kasper FK and Mikos

AG. Delivery of Plasmid DNA Encoding Bone Morphogenetic Protein-2 with a Biodegradable Branched Polycationic Polymer in a Critical-size Rat Cranial Defect Model, Tissue Engineering, Part A, 17(5-6):751-763, 2011. PMCID: PMC3044067

84. Kretlow JD, Spicer PP, Jansen JA, Vacanti CA, Kasper FK and Mikos AG. Uncultured

Marrow Mononuclear Cells Delivered within Fibrin Glue Hydrogels to Porous Scaffolds Enhance Bone Regeneration within Critical-sized Rat Cranial Defects, Tissue Engineering, Part A, 16(12):3555-3568, 2010. PMCID: PMC2992452

85. Liao J, Guo X, Grande-Allen KJ, Kasper FK and Mikos AG. Bioactive Polymer/Extracellular

Matrix Scaffolds Fabricated with a Flow Perfusion Bioreactor for Cartilage Tissue Engineering. Biomaterials, 31(34):8911-8920, 2010. PMCID: PMC2953640

86. Ranganathan SI, Yoon DM, Henslee AM, Nair MB, Smid C, Kasper FK, Tasciotti E, Mikos

AG, Decuzzi P and Ferrari M. Shaping the Micromechanical Behavior of Multi-phase Composites for Bone Tissue Engineering. Acta Biomaterialia, 6(9):3448-3456, 2010.

87. Chew SA, Hacker MC, Saraf A, Raphael RM, Kasper FK and Mikos AG. Altering Amine

Basicities in Biodegradable Branched Polycationic Polymers for Nonviral Gene Delivery. Biomacromolecules, 11(3):600-609, 2010. PMCID: PMC2842827

88. Burdett E, Kasper FK, Mikos AG and Ludwig JA. Engineering Tumors: A Tissue Engineering

Perspective in Cancer Biology. Tissue Engineering, Part B: Reviews, 16(3):351-359, 2010. 89. Liao J, Guo X, Nelson D, Kasper FK and Mikos AG. Modulation of Osteogenic Properties of

Biodegradable Polymer/Extracellular Matrix Scaffolds Generated with a Flow Perfusion Bioreactor. Acta Biomaterialia, 6(7):2386-2393, 2010. PMCID: PMC2874124

90. Shi M, Kretlow JD, Nguyen A, Young S, Baggett LS, Wong ME, Kasper FK and Mikos AG.

Antibiotic-releasing Porous Polymethylmethacrylate Constructs for Osseous Space Maintenance and Infection Control. Biomaterials, 31(14):4146-4156, 2010. PMCID: PMC2839066


91. Kretlow JD, Shi M, Young S, Spicer PP, Demian N, Jansen JA, Wong ME, Kasper FK and

Mikos AG. Evaluation of Soft Tissue Coverage over Porous Polymethylmethacrylate Space Maintainers within Nonhealing Alveolar Bone Defects. Tissue Engineering, Part C: Methods, 16(6):1427-1438, 2010. PMCID: PMC3003916

92. Guo X, Liao J, Park H, Saraf A, Raphael RM, Tabata Y, Kasper FK and Mikos AG. Effects of

TGF-β3 and Preculture Period of Osteogenic Cells on the Chondrogenic Differentiation of Rabbit Marrow Mesenchymal Stem Cells Encapsulated in a Bilayered Hydrogel Composite. Acta Biomaterialia, 6(8): 2920-2931, 2010. PMCID: PMC2882985

93. Martins AM, Saraf A, Sousa RA, Alves CM, Mikos AG, Kasper FK and Reis RL. Combination

of Enzymes and Flow Perfusion Conditions Improves Osteogenic Differentiation of Bone Marrow Stromal Cells Cultured upon Starch/Poly(ε-caprolactone) Fiber Meshes. Journal of Biomedical Materials Research: Part A, 94(4):1061-1069, 2010.

94. Guo X, Park H, Young S, Kretlow JD, van den Beucken JJ, Baggett LS, Tabata Y, Kasper

FK, Mikos AG, Jansen JA. Repair of Osteochondral Defects with Biodegradable Hydrogel Composites Encapsulating Marrow Mesenchymal Stem Cells in a Rabbit Model. Acta Biomaterialia, 6(1):39-47, 2010. PMCID: PMC2787824

95. Martins AM, Alves CM, Kasper FK, Mikos AG and Reis RL. Naturally Derived Responsive

and In Situ-forming Scaffolds for Bone Tissue Engineering Applications: An Overview of the Last Decade. Journal of Materials Chemistry, 20:1638-1645, 2010.

96. Saraf A, Baggett LS, Raphael RM, Kasper FK and Mikos AG. Regulated Non-viral Gene

Delivery from Coaxial Electrospun Fiber Mesh Scaffolds. Journal of Controlled Release, 143(1):95-103, 2010. PMCID: PMC2840180

97. Thibault RA, Baggett LS, Mikos AG and Kasper FK. Osteogenic Differentiation of

Mesenchymal Stem Cells on Pregenerated Extracellular Matrix Scaffolds in the Absence of Osteogenic Cell Culture Supplements. Tissue Engineering, Part A, 16(2):431-440, 2010. PMCID: PMC2813072

98. Zhang MW, Park H, Guo X, Nakamura K, Raphael RM, Kasper FK, Mikos AG and Tsonis PA.

Adapting Biodegradable Oligo(poly(ethylene glycol) fumarate) Hydrogels for Pigment Epithelial Cell Encapsulation and Lens Regeneration. Tissue Engineering, Part C: Methods, 16(2):261-267, 2010. PMCID: PMC2946905

99. Park H, Guo X, Temenoff JS, Tabata Y, Caplan AI, Kasper FK and Mikos AG. Effect of

Swelling Ratio of Injectable Hydrogel Composites on Chondrogenic Differentiation of Encapsulated Rabbit Marrow Mesenchymal Stem Cells In Vitro. Biomacromolecules, 10(3):541-546, 2009. PMCID: PMC2765566

100. Chew SA, Hacker MC, Saraf A, Raphael RM, Kasper FK and Mikos AG. Biodegradable

Branched Polycationic Polymers with Varying Hydrophilic Spacers for Non-viral Gene Delivery. Biomacromolecules, 10(9):2436-45, 2009. PMCID: PMC2743757

101. Kasper FK, Tanahashi K, Fisher JP and Mikos AG. Synthesis of Poly(propylene fumarate).

Nature Protocols, 4(4):518-525, 2009. PMCID: PMC3076598


102. Pham QP, Kasper FK, Mistry AS, Sharma U, Yasko AW, Jansen JA and Mikos AG. Analysis of the Osteoinductive Capacity and Angiogenicity of an In Vitro Generated Extracellular Matrix. Journal of Biomedical Materials Research: Part A, 88(2):295-303, 2009.

103. Guo X, Park H, Liu G, Liu W, Cao Y, Tabata Y, Kasper FK and Mikos AG. In Vitro

Generation of an Osteochondral Construct Using Injectable Hydrogel Composites Encapsulating Rabbit Marrow Mesenchymal Stem Cells. Biomaterials, 30(14):2741-2752, 2009. PMCID: PMC2877597

104. Saraf A, Lozier G, Haesslein A, Kasper FK, Raphael RM, Baggett LS and Mikos AG.

Fabrication of Nonwoven Coaxial Fiber Meshes by Electrospinning. Tissue Engineering, Part C: Methods, 15(3):333-344, 2009. PMCID: PMC2738761

105. Martins AM, Pham QP, Malafaya PB, Raphael RM, Kasper FK, Reis RL and Mikos AG.

Natural Stimulus Responsive Scaffolds/Cells for Bone Tissue Engineering: Influence of Lysozyme upon Scaffold Degradation and Osteogenic Differentiation of Cultured Marrow Stromal Cells Induced by CaP Coatings. Tissue Engineering, Part A, 15(8):1953-1963, 2009.

106. Martins AM, Pham QP, Malafaya PB, Sousa RA, Gomes ME, Raphael RM, Kasper FK, Reis

RL and Mikos AG. The Role of Lipase and α-amylase in the Degradation of Starch/Poly(ε-caprolactone) Fiber Meshes and the Osteogenic Differentiation of Cultured Marrow Stromal Cells. Tissue Engineering, Part A, 15(2):295-305, 2009. PMCID: PMC2810216

107. Pham QP, Kasper FK, Baggett LS, Raphael RM, Jansen JA and Mikos AG. The Influence of

an In Vitro Generated Bone-like Extracellular Matrix on Osteoblastic Gene Expression of Marrow Stromal Cells. Biomaterials, 29(18):2729-2739, 2008.

108. Kasper FK, Jerkins E, Tanahashi K, Barry MA, Tabata Y and Mikos AG. Characterization of

DNA Release from Composites of Oligo(poly(ethylene glycol) fumarate) and Cationized Gelatin Microspheres In Vitro. Journal of Biomedical Materials Research: Part A, 78(4):823-835, 2006.

109. Kasper FK, Young S, Tanahashi K, Barry MA, Tabata Y, Jansen JA and Mikos AG.

Evaluation of Bone Regeneration by DNA Release from Composites of Oligo(poly(ethylene glycol) fumarate) and Cationized Gelatin Microspheres in a Critical-sized Calvarial Defect. Journal of Biomedical Materials Research: Part A, 78(2):335-342, 2006.

110. Kasper FK, Kushibiki T, Kimura Y, Mikos AG and Tabata Y. In Vivo Release of Plasmid DNA

from Composites of Oligo(poly(ethylene glycol) fumarate) and Cationized Gelatin Microspheres. Journal of Controlled Release, 107(3):547-561, 2005.

111. Kasper FK, Seidlits SK, Tang A, Crowther RS, Carney DH, Barry MA and Mikos AG. In Vitro

Release of Plasmid DNA from Oligo(poly(ethylene glycol) fumarate) Hydrogels. Journal of Controlled Release, 104(3):521-539, 2005.

112. Barber JE, Kasper FK, Ratliff NB, Cosgrove DM, Griffin BP and Vesely I. Mechanical

Properties of Myxomatous Mitral Valves. Journal of Thoracic and Cardiovascular Surgery, 122(5):955-962, 2001.

C. Invited Articles (Reviews, Editorials, etc.) in Journals


D. Book Chapters

1. Tatara AM, Ratcliffe A, Wong MEK, Kasper FK and Mikos AG. “Biomaterials in Regenerative Medicine: Considerations in Early Process Development” in Translational Regenerative Medicine, Atala A and Allickson J, Eds., Elsevier, Oxford, submitted.

2. Lu S, Kim K, Lam J, Kasper FK and Mikos AG. “Fumarate–Based Hydrogels in Regenerative

Medicine Applications” in Biomaterials and Regenerative Medicine, Ma PX, Ed., Cambridge University Press, Cambridge, in press.

3. Trachtenberg JE, Kasper FK and Mikos AG. “Chapter 22: Polymer Scaffold Fabrication” in

Principles of Tissue Engineering, 4th Edition, Lanza R, Langer R and Vacanti JP, Eds., Elsevier, Oxford, pp. 423-440, 2014.

4. Kinard LA, Mikos AG and Kasper FK. “Bone Engineering” in Biomedical Engineering

Handbook, 4th Edition, Volume 4: Molecular Engineering, Bronzino JD and Peterson DR, Eds., CRC Press, Boca Raton, pp. 27.1-27.19, 2013.

5. Singh M, Kasper FK and Mikos AG. “Tissue Engineering Scaffolds” in Biomaterials Science:

An Introduction to Materials in Medicine, 3rd Edition, Ratner BD, Hoffman AS, Schoen FJ and Lemons JE, Eds., Academic Press, San Diego, pp. 1138-1159, 2013.

6. Hammerick KE, Mikos AG and Kasper FK. “Drug Delivery in Tissue Engineering: Physiologic

Considerations and Mechanical Issues for Bone” in Nanostructured Biomaterials for Overcoming Biological Barriers, Alonso MJ and Csaba NS, Eds., RSC Publishing, Cambridge, 526-547, 2012.

7. Shi X, Henslee A, Yoon D, Kasper FK and Mikos AG. “Poly(propylene fumarate)” in An

Introduction to Biomaterials, 2nd Edition, Hollinger JO, Ed., CRC Press, Boca Raton, pp. 317-330, 2012.

8. Kim K, Yoon DM, Mikos AG and Kasper FK. “Harnessing Cell-biomaterial Interactions for

Osteochondral Tissue Regeneration” in Adv Biochemical Engineering/Biotechnology, Special Volume 126: Tissue Engineering III: Cell - Surface Interactions for Tissue Culture, Kasper C, Witte F and Pörtner R, Eds., Springer, Heidelberg, pp. 67-104, 2012. PMCID: PMC3664097

9. Levorson EJ, Kasper FK and Mikos AG. “Scaffolds: Flow Perfusion Bioreactor Design” in

Comprehensive Biomaterials, Volume 5, Ducheyne P, Healy KE, Hutmacher DW, Grainger DW, Kirkpatrick CJ, Eds., Elsevier, Oxford, pp. 1-11, 2011.

10. Martins AM, Alves CM, Reis RL, Mikos AG and Kasper FK. “Towards Osteogenic

Differentiation of Marrow Stromal Cells and In Vitro Production of Mineralized Extracellular Matrix onto Natural Scaffolds” in Biological Interactions on Materials Surfaces: Understanding and Controlling Protein, Cell and Tissue Responses, Bizios R and Puleo D, Eds., Springer, San Diego, pp. 263-281, 2009.

11. Kasper FK, Liao J, Kretlow JD, Sikavitsas VI and Mikos AG. “Flow Perfusion Culture of

Mesenchymal Stem Cells for Bone Tissue Engineering,” in StemBook: Tissue Engineering, S


Bhatia and J Polak, Eds., Harvard Stem Cell Institute, Cambridge, 2008. (DOI: 10.3824/stembook.1.18.1; http://www.stembook.org)

12. Temenoff JS, Kasper FK and Mikos AG. “Fumarate-based Macromers as Scaffolds for Tissue

Engineering Applications,” in Topics in Tissue Engineering, Vol. 3, N Ashammakhhi, RL Reis and E Chiellini, Eds., pp. 6.1-6.16, 2007.

13. Kasper FK and Mikos AG. “Biomaterials and Gene Therapy,” in Molecular and Cellular

Foundations of Biomaterials, NA Peppas and MV Sefton, Eds., Academic Press, San Diego, pp. 131-168, 2004.

E. Books None

F. Other Professional Communications a) Presentations at National and International Meetings (*Presenter) 1. “Promoting Mineralization and Mesenchymal Stem Cell Differentiation in Injectable,

Physically and Chemically Gelling Hydrogels for Craniofacial Tissue Engineering,” 2014 Annual Meeting of the Society For Biomaterials, Denver, Colorado (April 16-19, 2014) With Vo TN*, Roh TL, Ekenseair AK, Kasper FK and Mikos AG. (Oral Presentation)

2. “Mitigation of Biofilm Formation with an Elastomeric Barrier Membrane System,” 2014

Annual Meeting of the Society For Biomaterials, Denver, Colorado (April 16-19, 2014) With Tatara AM*, Shah SR, Puperi DS, Watson BM, Wong MEK, Grande-Allen KJ, Mikos AG and Kasper FK. (Oral Presentation)

3. “Promoting In Vitro Mineralization and Stem Cell Differentiation in Injectable, Dual-gelling Hydrogels for Craniofacial Tissue Engineering,” 2014 Annual Meeting of the American Association for Dental Research, Charlotte, North Carolina. (March 19-22, 2014) With Vo TN*, Roh TT, Ekenseair AK, Kasper FK and Mikos AG. (Poster Presentation)

4. “Oligo(poly(ethylene glycol) fumarate) as a Synthetic Hydrogel Carrier for Demineralized

Bone Matrix,” TERMIS-Americas Annual Conference and Exposition, Atlanta, Georgia. (November 10-13, 2013) With Kinard LA*, Kasper FK and Mikos AG. (Oral Presentation)

5. “Articular Chondrocyte and Mesenchymal Stem Cell Co-cultures in Hydrogels for

Osteochondral Tissue Engineering,” TERMIS-Americas Annual Conference and Exposition, Atlanta, Georgia. (November 10-13, 2013) With Lam J*, Dahlin RL, Lu S, Tabata Y, Mikos AG and Kasper FK. (Poster Presentation)

6. “Enhancing the Chondrogenic Phenotype of Articular Chondrocytes in Flow Perfusion,”

TERMIS- Americas Annual Conference and Exposition, Atlanta, Georgia. (November 10-13, 2013) With Dahlin RL*, Meretoja VV, Ni M, Kasper FK and Mikos AG. (Poster Presentation)


http://www.stembook.org/

7. “Synthesis and Characterization of Novel, In Situ Cross-linkable, Biodegradable, Thermoresponsive Hydrogels for Bone Tissue Engineering” 2013 AIChE Annual Meeting, San Francisco, California. (November 3-8, 2013) With Watson BM*, Kasper FK, Engel PS and Mikos AG. (Oral Presentation)

8. “In Vitro Tumor Model Generated Using a Flow Perfusion Bioreactor,” Annual Meeting of

the Biomedical Engineering Society, Seattle, Washington (September 25-28, 2013) With Santoro M*, Lamhamedi-Cherradi SE, Kasper FK, Ludwig JA and Mikos AG. (Poster Presentation)

9. “Chondrogenic and Osteogenic Pre-differentiation of Mesenchymal Stem Cells for

Osteochondral Tissue Engineering using Bilayered Hydrogels,” Annual Meeting of the Biomedical Engineering Society, Seattle, Washington (September 25-28, 2013) With Lam J*, Lu S, Mikos AG and Kasper FK. (Poster Presentation)

10. “Effect of Chondrocyte Dedifferentiation on 3D Co-cultures with Mesenchymal Stem Cells,”

Annual Meeting of the Biomedical Engineering Society, Seattle, Washington (September 25-28, 2013) With Meretoja VV*, Dahlin RL, Kasper FK and Mikos AG. (Oral Presentation)

11. “Engineering a Three-dimensional In Vitro Model of Bone Sarcoma for Drug-testing” 2013

Annual Meeting of the Society For Biomaterials, Boston, Massachusetts. (April 10-13, 2013) With Fong ELS*, Lamhamedi-Cherradi S-E, Burdett E, Ramamoorthy V, Lazar AJ, Kasper FK, Farach-Carson MC, Vishwamitra D, Demicco EG, Menegaz BA, Amin HM, Ludwig JA and Mikos AG. (Oral Presentation)

12. “Tissue Response to Hydrogel Scaffolds Delivering Bone Morphogenetic Protein-2 for

Bone Augmentation” 2013 Annual Meeting of the Society For Biomaterials, Boston, Massachusetts. (April 10-13, 2013) With Kinard LA*, Dahlin RL, Henslee AM, Spicer PP, Chu C, Kasper FK and Mikos AG. (Poster Presentation)

13. “Dose Response to TGF-β3 of Co-cultured Chondrocytes and Mesenchymal Stem Cells

on Porous Polymer Scaffolds” 2013 Annual Meeting of the Society For Biomaterials, Boston, Massachusetts. (April 10-13, 2013) With Dahlin RL*, Ni M, Meretoja VV, Kasper FK and Mikos AG. (Oral Presentation)

14. “Devitalized Cell Derived Polymer/Extracellular Matrix Composite Scaffolds for Cartilage

Regeneration” 2013 Annual Meeting of the Society For Biomaterials, Boston, Massachusetts. (April 10-13, 2013) With Levorson EJ*, Hu O, Kasper FK and Mikos AG. (Accepted for Poster Presentation)

15. “Modulation of Polymer/DNA Release from Poly(lactic-co-glycolic acid) Microspheres

through Poly(ethylenimine) Modification and Loading Concentration” 2013 Annual Meeting of the Society For Biomaterials, Boston, Massachusetts. (April 10-13, 2013) With Needham C*, Shah SR, Kasper FK and Mikos AG. (Oral Presentation)

16. “Antibiotic-loaded Porous Poly(methyl methacrylate) for Space Maintenance and Local

Drug Delivery” 2013 Annual Meeting of the Society For Biomaterials, Boston, Massachusetts. (April 10-13, 2013) With Shah SR*, Raindel N, Henslee AM, Spicer PP, Kasper FK and Mikos AG. (Poster Presentation)


17. “Degradation and Characterization of Porous Constructs for Craniofacial Space Maintenance and Antibiotic Delivery” 2013 Annual Meeting of the Society For Biomaterials, Boston, Massachusetts. (April 10-13, 2013) With Henslee AM*, Shah SR, Spicer PP, Mikos AG and Kasper FK. (Poster Presentation)

18. “Longevity of Implant-associated Infectious Biofilms” 2013 Annual Meeting of the Society

For Biomaterials, Boston, Massachusetts. (April 10-13, 2013) With Tatara AM,* Kasper FK and Mikos AG. (Poster Presentation)

19. “Biocompatibility Evaluation of Poly(N-isopropylacrylamide)-based Hydrogels for

Craniofacial Bone Regeneration” 2013 Annual Meeting of the Society For Biomaterials, Boston, Massachusetts. (April 10-13, 2013) With Vo TN*, Ekenseair AK, Spicer PP, Watson BM, Kasper FK and Mikos AG. (Oral Presentation)

20. “Evaluation of Polyamidoamine-based Dual-hardening, Injectable Hydrogels for Tissue

Engineering” 2012 AIChE Annual Meeting, Pittsburgh, Pennsylvania. (October 28-November 2, 2012) With Ekenseair AK*, Tzouanas SN, Boere KWM, Vo TN, Kasper FK and Mikos AG. (Oral Presentation)

21. “3D Co-cultures of Chondrocytes and MSCs are Resistant to Hypertrophy in Normoxia and

Hypoxia” Annual Meeting of the Biomedical Engineering Society, Atlanta, Georgia. (October 24-27, 2012) With Meretoja VV*, Dahlin RL, Kasper FK and Mikos AG. (Oral Presentation)

22. “Cell-laden Microporous Hydrogels Using Carboxymethylcellulose as a Porogen for

Cartilage Regeneration” Annual Meeting of the Biomedical Engineering Society, Atlanta, Georgia. (October 24-27, 2012) With Wang L*, Kasper FK and Mikos AG. (Poster Presentation)

23. “Fabrication of Cell-laden Microporous Hydrogels Using Gelatin as a Porogen for Bone

Regeneration” Annual Meeting of the Biomedical Engineering Society, Atlanta, Georgia. (October 24-27, 2012) With Wang L*, Kasper FK and Mikos AG. (Oral Presentation)

24. “Characterization of Porous Polymethymethacrylate for Craniofacial Reconstruction”

Annual Meeting of the Biomedical Engineering Society, Atlanta, Georgia. (October 24-27, 2012) With Wang L*, Yoon DM, Spicer PP, Henslee AM, Kasper FK and Mikos AG. (Oral Presentation)

25. “Swelling and Mechanical Behavior of Novel Thermally and Chemically Gelling Injectable

Hydrogels” Annual Meeting of the Biomedical Engineering Society, Atlanta, Georgia. (October 24-27, 2012) With Ekenseair AK*, Boere KWM, Vo TN, Kasper FK and Mikos AG. (Poster Presentation)

26. “Accelerated Osteogenesis of Human Mesenchymal Stem Cells in Co-culture with

Endothelial Cells in 3D Scaffolds” Annual Meeting of the Biomedical Engineering Society, Atlanta, Georgia. (October 24-27, 2012) With Gershovich JG, Kasper FK* and Mikos AG. (Oral Presentation)

27. “Porous Polymethylmethacrylate Fabricated Intraoperatively as a Mandibular Space

Maintainer Post Tumor Resection: A Case Series” 3rd Tissue Engineering and Regenerative Medicine International Society World Congress, Vienna, Austria.


(September 5-8, 2012) With Spicer PP, Henslee AM, Nawab A, Demian N, Kasper FK* and Mikos AG. (Poster Presentation)

28. “Controlled Delivery of rhBMP-2 from OPF Hydrogel Composites for Bone Tissue

Engineering” 3rd Tissue Engineering and Regenerative Medicine International Society World Congress, Vienna, Austria. (September 5-8, 2012) With Kinard LA*, Chu C, Kasper FK and Mikos AG. (Oral Presentation)

29. “Dual Growth Factor Delivery from Bilayered Composite Hydrogels for Osteochondral

Tissue Repair in a Rabbit Model” 3rd Tissue Engineering and Regenerative Medicine International Society World Congress, Vienna, Austria. (September 5-8, 2012) With Kim K*, Lam J, Lu S, Tabata Y, Mikos AG and Kasper FK. (Poster Presentation)

30. “Flow Perfusion Co-culture of Articular Chondrocytes and MSCs” 3rd Tissue Engineering

and Regenerative Medicine International Society World Congress, Vienna, Austria. (September 5-8, 2012) With Dahlin RL*, Meretoja VV, Ni M, Kasper FK and Mikos AG. (Poster Presentation)

31. “Evaluation of Antibiotic-releasing Porous Polymethylmethacrylate Space Maintainers in

an Infected Composite Tissue Defect” 39th Annual Meeting of the Controlled Release Society, Québec City, Canada. (July 15-18, 2012) With Spicer PP*, Henslee AM, Kinard LA, Watson BM, Kretlow JD, Bevil K, Katchee L, Jansen JA, Wong ME, Kasper FK and Mikos AG. (Oral Presentation)

32. “Development of Porous Poly(methyl methacrylate) Space Maintainers for Craniofacial

Tissue Engineering” 9th World Biomaterials Congress, Chengdu, China. (June 1-5, 2012) With Mikos AG*, Wong ME and Kasper FK. (Oral Presentation)

33. “Synthesis and Cytocompatibility of Novel Injectable, In Situ Hardening Hydrogels Based

on Poly(N-isopropylacrylamide) and Polyamidoamines” 9th World Biomaterials Congress, Chengdu, China. (June 1-5, 2012) With Ekenseair AK*, Tzouanas SN, Boere KWM, Vo TN, Kasper FK and Mikos AG. (Oral Presentation)

34. “Three Dimensional Quantitative Imaging of Biomaterials with X-ray Phase Contrast” 9th

World Biomaterials Congress, Chengdu, China. (June 1-5, 2012) With Appel AA*, Larson J, Somo S, Spicer PP, Kasper FK, Mikos AG, Anastasio MA and Brey EM (Oral Presentation).

35. “Injectable Thermogelling and Chemically Crosslinked Scaffolds with Hydrolysis-

dependent LCST for Craniofacial Bone Regeneration” 9th World Biomaterials Congress, Chengdu, China. (June 1-5, 2012) With Vo TN*, Ekenseair AK, Boere KWM, Kasper FK and Mikos AG. (Poster Presentation)

36. “Delivery of Induced Pluripotent Stem Cells Derived Cardiomyocytes and bFGF via

Injectable, Biodegradable Hydrogels for the Treatment of Myocardial Infarction” 9th World Biomaterials Congress, Chengdu, China. (June 1-5, 2012) With Wang H*, Kinard L, Liu Z, Chen W, Kasper FK, Zhou J, Lin Q, Duan C, Wang Y, Mikos AG and Wang C. (Oral Presentation)


37. “Fabrication of Antibiotic-loaded Biodegradable Polymer Microspheres for Infection Control” 9th World Biomaterials Congress, Chengdu, China. (June 1-5, 2012) With Shah SR*, Henslee AM, Spicer PP, Kasper FK* and Mikos AG. (Poster Presentation)

38. “Delivery of Growth Factors and Mesenchymal Stem Cells Using Bilayered Hydrogels for

Osteochondral Tissue Regeneration” 2nd International Conference on Nanotechnology at the Bio-Medical Interface (NANOBIO 2012), Kochi, Kerala, India. (February 21-23, 2012) With Kim K, Lu S, Tabata Y, Mikos AG* and Kasper FK (Poster Presentation)

39. “Evaluation of Antibiotic-releasing Porous Polymethylmethacrylate Space Maintainers in

an Infected Composite Tissue Defect” 2012 Armed Forces Institute of Regenerative Medicine “All Hands” Meeting, St. Pete Beach, Florida. (February 13-15, 2012) With Spicer PP, Henslee AM, Kinard LA, Watson BM, Kretlow JD, Bevil K, Katchee L, Wong ME, Mikos AG and Kasper FK*. (Oral and Poster Presentations)

40. “Fabrication of Antibiotic-loaded Biodegradable Polymer Microspheres for Infection

Control” 2012 Armed Forces Institute of Regenerative Medicine “All Hands” Meeting, St. Pete Beach, Florida. (February 13-15, 2012) With Shah SR, Henslee AM, Spicer PP, Wong ME, Kasper FK* and Mikos AG (Poster Presentation)

41. “Characterization of Polymethylmethacrylate/Gelatin Constructs for Osseous Space

Maintenance and Antibiotic Delivery” TERMIS-North America Annual Conference and Exposition, Houston, Texas. (December 11-14, 2011) With Spicer PP*, Shi M, Demian N, Wong ME, Kasper FK and Mikos AG. (Oral Presentation)

42. “Characterizing an Injectable Synthetic Biodegradable Polymer to Mechanically Stabilize

Mandibular Defects” TERMIS-North America Annual Conference and Exposition, Houston, Texas. (December 11-14, 2011) With Yoon DM*, Henslee AM, Lu BY, Arango AA, Marruffo LP, Seng LJ, Anver TD, Ather H, Demian N, Wong MEK, Kasper FK and Mikos AG. (Oral Presentation)

43. “Development of a Biodegradable Bone Cement for Craniofacial Applications” TERMIS-

North America Annual Conference and Exposition, Houston, Texas. (December 11-14, 2011) With Henslee AM*, Gwak DH, Wong ME, Mikos AG and Kasper FK. (Poster Presentation)

44. “Dual Growth Factor Release from Bilayered Oligo(poly(ethylene glycol) fumarate)

Hydrogels” TERMIS-North America Annual Conference and Exposition, Houston, Texas. (December 11-14, 2011) With Kim K*, Lam J, Lu S, Tabata Y, Mikos A.G. and Kasper FK. (Poster Presentation)

45. “Enhanced Chondrogenesis in Mesenchymal Stem Cell Cultures Supplemented with

Articular Chondrocytes” TERMIS-North America Annual Conference and Exposition, Houston, Texas. (December 11-14, 2011) With Meretoja VV*, Dahlin RL, Kasper FK and Mikos AG. (Poster Presentation)

46. “Injectable PNiPAAm-based Scaffolds with Tunable LCST for Craniofacial Bone

Regeneration” TERMIS-North America Annual Conference and Exposition, Houston, Texas. (December 11-14, 2011) With Vo TN*, Ekenseair AK, Boere KWM, Kasper FK and Mikos AG. (Poster Presentation)


47. “Injectable, Thermogelling Tissue Engineering Scaffolds Utilizing Polyamidoamines” TERMIS-North America Annual Conference and Exposition, Houston, Texas. (December 11-14, 2011) With Ekenseair AK*, Boere KWM, Touchet TJ, Kasper FK and Mikos AG. (Oral Presentation)

48. “Optimizing Encapsulation Densities of Cell Populations in Bilayered Hydrogels for

Osteochondral Tissue Engineering” TERMIS-North America Annual Conference and Exposition, Houston, Texas. (December 11-14, 2011) With Kim K*, Lu S, Lam J, Tabata Y, Mikos AG and Kasper FK. (Oral Presentation)

49. “Testing of a High Throughput Flow Perfusion Bioreactor for Osteochondral Tissue

Engineering” TERMIS-North America Annual Conference and Exposition, Houston, Texas. (December 11-14, 2011) With Dahlin RL*, Meretoja VV, Kasper FK and Mikos AG. (Oral Presentation)

50. “Three Dimensional Quantitative Imaging of Biomaterials in Engineered Tissues with X-ray

Phase Contrast” TERMIS-North America Annual Conference and Exposition, Houston, Texas. (December 11-14, 2011) With Appel AA*, Larson J, Somo S, Anastasio MA, Spicer PP, Kasper FK, Mikkos AG and Brey EM. (Oral Presentation)

51. “Protein and Mineral Composition of Osteogenic Constructs Generated within a Flow

Perfusion Bioreactor” 2011 AIChE Annual Meeting, Minneapolis, Minnesota. (October 16-21, 2011) With Thibault RA*, Kasper FK and Mikos AG. (Oral Presentation)

52. “Optimization of Thermogelling, Injectable Scaffolds for Craniofacial Tissue Regeneration”

2011 AIChE Annual Meeting, Minneapolis, Minnesota. (October 16-21, 2011) With Ekenseair AK*, Zuiker N, Kasper FK and Mikos AG. (Oral Presentation)

53. “A Novel Epoxy-based, Injectable Hydrogel Scaffold for Tissue Regeneration” 2011 AIChE

Annual Meeting, Minneapolis, Minnesota. (October 16-21, 2011) With Ekenseair AK*, Boere KWM, Kasper FK and Mikos AG. (Oral Presentation)

54. “Nanostructured Scaffolds For Regulating Osteogenic Differentiation of Induced

Pluripotent Stem Cells” Annual Meeting of the Biomedical Engineering Society, Hartford, Connecticut. (October 12-15, 2011) With Hammerick KE*, Kasper FK and Mikos AG. (Oral Presentation)

55. “The Effect of Primary Amines, Overall Charge, and Ligand Targeting on the Effectiveness

of Poly(ethylenimine)-hyaluronic Acid Conjugates as Gene Therapy Agents” Annual Meeting of the Biomedical Engineering Society, Hartford, Connecticut. (October 12-15, 2011) With Needham CJ*, Chew SA, Williams AK, Kasper FK and Mikos AG. (Poster Presentation)

56. “Antibiotic-releasing Porous Poly(methyl methacrylate) Space Maintainers for Craniofacial

Tissue Engineering” 38th Annual Meeting of the Controlled Release Society, National Harbor, Maryland. (July 30 - August 3, 2011) With Spicer PP, Shi M, Kretlow JD, Henslee AM, Young S, Demian N, Jansen JA, Wong ME, Kasper FK and Mikos AG*. (Oral Presentation)

57. “Porous Poly(methyl metharylate) Constructs for Osseous Space Maintenance and

Infection Control” TERMIS-Europe Annual Conference and Exposition, Granada, Spain.


(June 6-10, 2011) With Shi M, Spicer PP, Demian N, Wong ME, Mikos AG and Kasper FK*. (Oral Presentation)

58. “Harnessing Inflammation in Strategies for Bone Regeneration” 4th International

Conference on Tissue Engineering, Chania, Crete, Greece. (May 31-June 5, 2011) With Mountziaris PM, Tzouanas SN, Mikos AG and Kasper FK*. (Oral Presentation)

59. “Development of a 3D Tissue Engineered Cancer Model for Drug Screening” 4th

International Conference on Tissue Engineering, Chania, Crete, Greece. (May 31-June 5, 2011) With Burdett E, Kasper FK*, Mikos AG and Ludwig JA. (Oral and Poster Presentations)

60. “Calcium Alginate Porogens for the Development of an Injectable Paste to Treat Traumatic

Fractures” 2011 Annual Meeting of the Society For Biomaterials, Orlando, Florida. (April 13-16, 2011) With Buchanan RM*, Murphy MB, Yoon DM, Henslee AM, Nair M, Kasper FK, Simmons PJ, Mikos AG, Ferrari M and Tasciotti E. (Oral Presentation)

61. “Flow Perfusion Bioreactor for Bone and Cartilage Tissue Engineering” 2011 Annual

Meeting of the Society For Biomaterials, Orlando, Florida. (April 13-16, 2011) With Meretoja VV*, Dahlin RL, Kasper FK and Mikos AG. (Poster Presentation)

62. “In Situ Formation of Porous Poly(methyl methacrylate) Scaffolds for Space Maintenance

of Craniofacial Bone Defects” 2011 Armed Forces Institute of Regenerative Medicine “All Hands” Meeting, Clearwater, Florida. (January 17-21, 2011) With Spicer PP*, Henslee AM, Kretlow JD, Shi M, Young S, Demian N, Jansen JA, Wong ME, Kasper FK and Mikos AG. (Oral and Poster Presentations)

63. “Porous Poly(methyl methacrylate) Constructs for Osseous Space Maintenance and

Infection Control” 2011 Armed Forces Institute of Regenerative Medicine “All Hands” Meeting, Clearwater, Florida. (January 17-21, 2011) With Shi M*, Kretlow JD, Spicer PP, Demian N, Wong ME, Kasper FK and Mikos AG. (Poster Presentation)

64. “In Situ Formation of Porous Poly(methyl methacrylate) Space Maintainers for Craniofacial

Complex Regeneration” TERMIS-North America Annual Conference and Exposition, Orlando, Florida. (December 7-9, 2010) With Spicer PP*, Kretlow JD, Henslee AM, Shi M, Young S, Demian N, Jansen JA, Wong MEK, Kasper FK and Mikos AG. (Oral Presentation)

65. “Enhanced Chondrogenesis of Mesenchymal Stem Cells under Flow Perfusion

Conditions” TERMIS-North America Annual Conference and Exposition, Orlando, Florida. (December 7-9, 2010) With Meretoja VV*, Dahlin RL, Kasper FK and Mikos AG. (Poster Presentation)

66. “Developing In Situ Crosslinkable Scaffold to Mechanically Stabilize Mandibular Defects”

TERMIS-North America Annual Conference and Exposition, Orlando, Florida. (December 7-9, 2010) With Yoon DM*, Henslee AM, Arango AA, Marruffo LP, Nair MB, Anver TD, Ather H, Demian N, Wong MEK, Kasper FK and Mikos AG. (Poster Presentation)

67. “Fabrication and Characterization of Thermally Responsive, In Situ Crosslinkable

Hydrogels based on N-isopropylacrylamide” 2010 AIChE Annual Meeting, Salt Lake City,


Utah. (November 7-12, 2010) With Klouda L, Perkins KR, Kasper FK* and Mikos AG. (Oral Presentation)

68. “Controlled Release of Anti-tumor Necrosis Factor-alpha siRNA From Biodegradable

Polymeric Microparticles” 2010 AIChE Annual Meeting, Salt Lake City, Utah. (November 7-12, 2010) With Mountziaris P*, Sing DC, Chew SA, Tzouanas SN, Lehman ED, Kasper FK and Mikos AG. (Oral Presentation)

69. “Development and Optimization of a Biodegradable Bone Cement for Clinical Applications”

Annual Meeting of the Biomedical Engineering Society, Austin, Texas. (October 6-9, 2010) With Henslee A, Yoon DM*, Gwak D, Mikos AG and Kasper FK. (Oral Presentation)

70. “Effect of Patterned TNF-α Delivery on In Vitro Osteogenic Differentiation of Mesenchymal

Stem Cells” Annual Meeting of the Biomedical Engineering Society, Austin, Texas. (October 6-9, 2010) With Mountziaris P*, Lehman E, Kasper FK and Mikos AG. (Poster Presentation)

71. “The Development of a 3D Tissue Engineered Bone Tumor Model” Annual Meeting of the

Biomedical Engineering Society, Austin, Texas. (October 6-9, 2010) With Burdett E*, Mikos AG, Kasper FK and Ludwig J. (Oral Presentation)

72. “Cartilage Tissue Engineering Using Neonatal Human Dermal Fibroblasts” Annual Meeting

of the Biomedical Engineering Society, Austin, Texas. (October 6-9, 2010) With Singh M, Kasper FK* and Mikos AG. (Poster Presentation)

73. “Exploring Multi-domain Peptides and Gelatin Microparticles as an Osteogenic Factor

Delivery System” Annual Meeting of the Biomedical Engineering Society, Austin, Texas. (October 6-9, 2010) With Yoon DM*, Lu B, Bakota E, Kasper FK, Hartgerink J and Mikos AG. (Oral Presentation)

74. “Development of a Chondrogenic Pellet Preculture System for Cartilage Tissue

Engineering Applications” Annual Meeting of the Biomedical Engineering Society, Austin, Texas. (October 6-9, 2010) With Levorson EJ*, Kasper FK and Mikos AG. (Oral Presentation)

75. “Trifunctional Porogens for the Development of an Injectable Putty to Treat Traumatic

Bone Defects” Annual Meeting of the Biomedical Engineering Society, Austin, Texas. (October 6-9, 2010) With Buchanan R*, Murphy M, Yoon D, Liu X, Kasper FK, Simmons P, Mikos AG, Ferrari M and Tasciotti E. (Oral Presentation)

76. “Gelatin Microparticle-incorporating Poly(methyl methacrylate) Constructs for Craniofacial

Tissue Engineering” Advanced Technology Applications for Combat Casualty Care 2010, St. Pete Beach, Florida. (August 15-19, 2010) With Shi M, Kretlow JD, Young S, Wong ME, Kasper FK* and Mikos AG. (Oral Presentation)

77. “An Injectable Scaffold Exhibiting Staggered Bioactive Release through Multi-functional

Components for Bone Fracture Repair” 37th Annual Meeting of the Controlled Release Society, Portland, Oregon. (July 10-14, 2010) With Smid C, Buchanan R, Murphy M, Blashki D, Fan D, De Rosa E, Yoon D, Kasper FK, Liu X, Jones H, Noble P, Weiner B, Simmons P, Mikos AG, Ferrari M and Tasciotti E*. (Oral Presentation)


78. “Gelatin Microparticle-incorporating Poly(methyl methacrylate) Constructs for Craniofacial Tissue Engineering” 37th Annual Meeting of the Controlled Release Society, Portland, Oregon. (July 10-14, 2010) With Shi M, Kretlow JD, Young S, Wong ME, Kasper FK* and Mikos AG. (Poster Presentation)

79. “Gelatin Microparticle-incorporating Poly(methyl methacrylate) Constructs for Craniofacial

Tissue Engineering” 2010 Annual Meeting of the Society for Biomaterials, Seattle, Washington. (April 21-24, 2010) With Shi M, Kretlow JD, Young S, Wong ME, Kasper FK* and Mikos AG. (Poster Presentation)

80. “Emerging Controlled Release Approaches for Bone Tissue Engineering” 11th European

Symposium on Controlled Drug Delivery, Egmond aan Zee, The Netherlands. (April 6-9, 2010) With Shi M, Kretlow JD, Spicer PP, Nguyen A, Young S, Wong ME, Kasper FK and Mikos AG*. (Oral Presentation)

81. “Poly(lactic-co-glycolic acid) Microsphere-incorporating Poly(methyl methacrylate)

Constructs for Osseous Space Maintenance and Drug Delivery” ASME 2010 First Global Congress on NanoEngineering for Medicine and Biology, Houston, Texas. (February 7-10, 2010) With Shi M*, Kretlow JD, Young S, Wong ME, Kasper FK, and Mikos AG. (Oral Presentation)

82. “In Situ Formation of Porous Poly(methyl methacrylate) Scaffolds for Space Maintenance

of Craniofacial Bone Defects” 2010 Armed Forces Institute of Regenerative Medicine “All Hands” Meeting, St. Pete Beach, Florida. (January 11-14, 2010) With Spicer PP*, Kretlow JD, Shi M, Young S, Wong ME, Kasper FK, and Mikos AG. (Poster Presentation)

83. “Porous Poly(methyl methacrylate) Space Maintainers Promote Soft Tissue Coverage of

Clean/Contaminated Alveolar Bone Defects” 2010 Armed Forces Institute of Regenerative Medicine “All Hands” Meeting, St. Pete Beach, Florida. (January 11-14, 2010) With Kretlow JD, Shi M, Young S, Spicer PP*, Demien N, Jansen JA, Wong ME, Kasper FK, and Mikos AG. (Oral and Poster Presentations)

84. “Antibiotic-releasing Porous Poly(methyl methacrylate) Constructs for Osseous Space

Maintenance and Infection Control” 2010 Armed Forces Institute of Regenerative Medicine “All Hands” Meeting, St. Pete Beach, Florida. (January 11-14, 2010) With Shi M, Kretlow JD, Young S, Wong ME, Kasper FK*, and Mikos AG. (Oral and Poster Presentations)

85. “Antibiotic-releasing Porous Poly(methyl methacrylate) Scaffolds for Osseous Space

Maintenance and Infection Control” 2nd Tissue Engineering and Regenerative Medicine International Society World Congress, Seoul, Korea. (August 31-September 3, 2009) With Kasper FK*, Shi M, Kretlow JD, Young S, Wong ME and Mikos AG. (Oral Presentation)

86. “Porous Poly(methyl methacrylate) Implants for Osseous Space Maintenance and

Promotion of Soft Tissue Healing around Craniofacial Bone Defects” 2nd Tissue Engineering and Regenerative Medicine International Society World Congress, Seoul, Korea. (August 31-September 3, 2009) With Kretlow JD*, Shi M, Young S, Kasper FK, Wong ME and Mikos AG. (Oral Presentation)

87. “In Vitro Generation of an Osteochondral Construct Using Injectable Hydrogel Composites

Encapsulating Rabbit Marrow Mesenchymal Stem Cells” 2nd Tissue Engineering and


Regenerative Medicine International Society World Congress, Seoul, Korea. (August 31-September 3, 2009) With Guo X*, Park H, Kasper FK and Mikos AG. (Oral Presentation)

88. “Regulated Non-viral Gene Delivery from Coaxial Electrospun Fiber Mesh Scaffolds” 2nd

Tissue Engineering and Regenerative Medicine International Society World Congress, Seoul, Korea. (August 31-September 3, 2009) With Kasper FK*, Saraf A, Baggett LS and Mikos AG. (Poster Presentation)

89. “Towards Osteogenic Differentiation of Bone Marrow Stromal Cells Cultured onto

Starch/Poly(ε-caprolactone) Fiber Mesh Scaffolds: The Efficiency of Enzymes and Flow Perfusion Bioreactors” 2nd Tissue Engineering and Regenerative Medicine International Society World Congress, Seoul, Korea. (August 31-September 3, 2009) With Reis RL*, Martins AM, Saraf A, Sousa RA, Kasper FK, Alves CM and Mikos AG. (Poster Presentation)

90. “In Vivo Responsive Scaffolds with the Ability of In Situ Pore Formation: A Novel Strategy

for Bone Tissue Engineering” 2nd Tissue Engineering and Regenerative Medicine International Society World Congress, Seoul, Korea. (August 31-September 3, 2009) With Costa-Pinto AR*, Martins AM, Kasper FK, Kretlow JD, Malafaya PB, Neves NM, Alves CM, Reis RL and Mikos AG. (Poster Presentation)

91. “In Vitro and In Vivo Characterization of Porous Poly(methyl methacrylate) Implants for

Osseous Space Maintenance Following Craniofacial Trauma” Advanced Technology Applications for Combat Casualty Care 2009, St. Pete Beach, Florida. (August 11, 2009) With Kretlow JD, Shi M, Young S, Spicer PP, Kasper FK*, Wong ME and Mikos AG. (Poster Presentation)

92. “Effect of Flow Perfusion on Osteogenic Differentiation of Mesenchymal Stem Cells

Cultured on Biodegradable Microfiber Scaffolds” 26th Annual Houston Conference on Biomedical Engineering Research, Houston, Texas. (March 19-20, 2009) With Liao J*, Kasper FK, and Mikos AG. (Oral Presentation)

93. “Characterization of Porous Poly(methyl methacrylate) Scaffold for Osseous Space

Maintenance” 26th Annual Houston Conference on Biomedical Engineering Research, Houston, Texas. (March 19-20, 2009) Shi M*, Kretlow JD, Young S, Kasper FK, Wong ME, and Mikos AG. (Oral Presentation)

94. “Porous Poly(methyl methacrylate) Implants for Osseous Space Maintenance Following

Craniofacial Injury” 2009 Armed Forces Institute of Regenerative Medicine “All Hands” Meeting, St. Pete Beach, Florida. (January 13-16, 2009) With Kretlow JD*, Shi M, Young S, Kasper FK, Wong ME, and Mikos AG. (Oral and Poster Presentations)

95. “Mineralized Extracellular Matrix Constructs Support the Osteogenic Differentiation of

Mesenchymal Stem Cells In Vitro” 2008 AIChE Annual Meeting, Philadelphia, Pennsylvania. (November 16-21, 2008) With Kasper FK*, Thibault RA, and Mikos AG. (Oral Presentation)

96. “Growth Factor and Cell Delivery for Cartilage Tissue Engineering” 3rd International

Conference on Tissue Engineering, Rhodes, Greece. (September 21-26, 2008) With Kasper FK*, Guo X, Park H, and Mikos AG. (Oral Presentation)


97. “Extracellular Matrix Constructs Enhance the Osteogenic Differentiation of Marrow Stromal Cells In Vitro” 3rd International Conference on Tissue Engineering, Rhodes, Greece. (September 21-26, 2008) With Thibault RA*, Kasper FK, and Mikos AG. (Oral and Poster Presentations)

98. “Mineralized Extracellular Matrix Constructs for Bone Tissue Engineering” 10th

International Symposium on Biomineralization, Lianyungang, China. (August 31 - September 4, 2008) With Kasper FK, Thibault RA, and Mikos AG*. (Oral Presentation)

99. “Tissue Engineering and Its Future Perspective” 8th World Biomaterials Congress,

Amsterdam, The Netherlands. (May 28 - June 1, 2008) With Mikos AG* and Kasper FK. (Oral Presentation)

100. “Electrospun Poly(ε-caprolactone) Microfiber Scaffolds for Cartilage Regeneration” 8th

World Biomaterials Congress, Amsterdam, The Netherlands. (May 28 - June 1, 2008) With Liao J*, Guo X, Pham QP, Kasper FK, and Mikos AG. (Poster Presentation)

101. “The Role of Lipase and α-amylase in both the Degradation of Starch/Polycaprolactone

Fiber Meshes and the Osteogenic Differentiation of Rat Marrow Stromal Cells” 8th World Biomaterials Congress, Amsterdam, The Netherlands. (May 28 - June 1, 2008) With Martins AM*, Pham QP, Malafaya PB, Sousa RA, Gomes ME, Kasper FK, Reis RL, and Mikos AG. (Oral Presentation)

102. “Fabrication of Coaxial Fiber Meshes by Electrospinning” 5th Marie Curie Cutting-edge

InVENTS Conference on Synthesis and Applications of Self-assembling Materials at Nano-scale, Madeira, Portugal. (April 15, 2008) With Saraf A*, Lozier G, Kasper FK, Raphael RM, Baggett LS, and Mikos AG. (Oral Presentation)

103. “Generation of Tissue Engineering Scaffolds with a Flow Perfusion Bioreactor” 8th

International Bone Fluid Flow Workshop, New York, New York. (September 14, 2007) With Kasper FK, Pham QP, and Mikos AG*. (Oral Presentation)

104. “Osteoinductive Capacity and Angiogenicity of an In Vitro Generated Extracellular Matrix”

3rd Marie Curie Cutting Edge InVENTS Conference on Biomineralisation of Polymeric Materials, Bioactive Biomaterials and Biomimetic Methodologies, Madeira, Portugal. (June 6, 2007) With Pham QP, Kasper FK*, Sharma U, Mistry AS, Yasko AW, Jansen JA, and Mikos AG. (Oral Presentation)

105. “Evaluation of Bone Regeneration by DNA Release from Composites of

Oligo(poly(ethylene glycol) fumarate) and Cationized Gelatin Microspheres in a Critical-sized Calvarial Defect” 33rd Annual Meeting of the Controlled Release Society, Vienna, Austria. (2006) With Kasper FK*, Young S, Tanahashi K, Barry MA, Tabata Y, Jansen JA and Mikos AG. (Poster Presentation)

106. “Characterization of DNA Release from Composites of Oligo(poly(ethylene glycol)

fumarate) and Cationized Gelatin Microspheres In Vitro” 31st Annual Meeting of the Society for Biomaterials, Pittsburgh, PA. (2006) With Kasper FK*, Jerkins E, Tanahashi K, Barry MA, Tabata Y and Mikos AG. (Oral Presentation)

107. “In Vivo Release of Plasmid DNA from Composites of Oligo(poly(ethylene glycol)

fumarate) and Cationized Gelatin Microspheres” 32nd Annual Meeting of the Controlled


Release Society, Miami, FL. (2005) With Kasper FK*, Kushibiki T, Kimura Y, Mikos AG and Tabata Y. (Poster Presentation)

108. “In Vitro Release of Plasmid DNA from Oligo(poly(ethylene glycol) fumarate) Hydrogels”

32nd Annual Meeting of the Controlled Release Society, Miami, FL. (2005) With Kasper FK*, Seidlits SK, Barry MA and Mikos AG. (Poster Presentation)

b) Proceedings

1. Fong ELS, Lamhamedi-Cherradi S-E, Burdett E, Ramamoorthy V, Lazar AJ, Kasper FK,

Farach-Carson MC, Vishwamitra D, Demicco EG, Menegaz BA, Amin HM, Ludwig JA and Mikos AG, “Engineering a Three-dimensional In Vitro Model of Bone Sarcoma for Drug-testing,” Trans. Soc. Biomater., 35:140, 2013.

2. Kinard LA, Dahlin RL, Henslee AM, Spicer PP, Chu C, Kasper FK and Mikos AG, “Tissue

Response to Hydrogel Scaffolds Delivering Bone Morphogenetic Protein-2 for Bone Augmentation,” Trans. Soc. Biomater., 35:161, 2013.

3. Dahlin RL, Ni M, Meretoja VV, Kasper FK and Mikos AG, “Dose Response to TGF-β3 of

Co-cultured Chondrocytes and Mesenchymal Stem Cells on Porous Polymer Scaffolds” Trans. Soc. Biomater., 35:330, 2013.

4. Levorson EJ, Hu O, Kasper FK and Mikos AG, “Devitalized Cell Derived

Polymer/Extracellular Matrix Composite Scaffolds for Cartilage Regeneration,” Trans. Soc. Biomater., 35:414, 2013.

5. Needham C, Shah SR, Kasper FK and Mikos AG, “Modulation of Polymer/DNA Release

from Poly(lactic-co-glycolic acid) Microspheres through Poly(ethylenimine) Modification and Loading Concentration,” Trans. Soc. Biomater., 35:93, 2013.

6. Shah SR, Raindel N, Henslee AM, Spicer PP, Kasper FK and Mikos AG, “Antibiotic-

loaded Porous Poly(methyl methacrylate) for Space Maintenance and Local Drug Delivery,” Trans. Soc. Biomater., 35:588, 2013.

7. Henslee AM, Shah SR, Spicer PP, Mikos AG and Kasper FK, “Degradation and

Characterization of Porous Constructs for Craniofacial Space Maintenance and Antibiotic Delivery,” Trans. Soc. Biomater., 35:952, 2013.

8. Tatara AM, Kasper FK and Mikos AG, “Longevity of Implant-associated Infectious

Biofilms,” Trans. Soc. Biomater., 35:662, 2013. 9. Vo TN, Ekenseair AK, Spicer PP, Watson BM, Kasper FK and Mikos AG,

“Biocompatibility Evaluation of Poly(N-isopropylacrylamide)-based Hydrogels for Craniofacial Bone Regeneration,” Trans. Soc. Biomater., 35:156, 2013.

10. Spicer PP, Henslee AM, Kinard LA, Watson BM, Kretlow JD, Bevil K, Katchee L, Jansen

JA, Wong ME, Kasper FK and Mikos AG, “Evaluation of Antibiotic-releasing Porous Polymethylmethacrylate Space Maintainers in an Infected Composite Tissue Defect,” Trans. Control. Rel. Soc., 39:103, 2012.


11. Shah S, Henslee AM, Spicer PP, Kasper FK and Mikos AG, “Fabrication of Antibiotic-loaded Biodegradable Polymer Microspheres for Infection Control,” Trans. World Biomater. Congr., 9:P-SAT-C-201, 2012.

12. Vo TN, Ekenseair AK, Boere KWM, Kasper FK and Mikos AG, “Injectable Thermogelling

and Chemically Crosslinked Scaffolds with Hydrolysis-dependent LCST for Craniofacial Bone Regeneration,” Trans. World Biomater. Congr., 9:P-SAT-A-153, 2012.

13. Ekenseair AK, Mikos AG, Tzouanas SN, Boere KWM, Vo TN and Kasper FK, “Synthesis

and Cytocompatibility of Novel Injectable, In Situ Hardening Hydrogels Based on Poly(N-isopropylacrylamide) and Polyamidoamines,” Trans. World Biomater. Congr., 9:S167b, 2012.

14. Appel AA, Larson J, Somo S, Spicer PP, Kasper FK, Mikos AG, Anastasio MA and Brey

EM, “Three Dimensional Quantitative Imaging of Biomaterials with X-ray Phase Contrast,” Trans. World Biomater. Congr., 9:S131a, 2012.

15. Wang H, Kinard LA, Liu Z, Chen W, Kasper FK, Zhou J, Lin Q, Duan C, Wang Y, Mikos

AG and Wang C, “Delivery of Induced Pluripotent Stem Cells Derived Cardiomyocytes and bFGF via Injectable, Biodegradable Hydrogels for the Treatment of Myocardial Infarction,” Trans. World Biomater. Congr., 9:S124b, 2012.

16. Mikos AG, Wong ME and Kasper FK, “Development of Porous Poly(methyl methacrylate)

Space Maintainers for Craniofacial Tissue Engineering,” Trans. World Biomater. Congr., 9:S002c, 2012.

17. Spicer PP, Shi M, Kretlow JD, Henslee AM, Young S, Demian N, Jansen JA, Wong ME,

Kasper FK and Mikos AG, “Antibiotic-releasing Porous Poly(methyl methacrylate) Space Maintainers for Craniofacial Tissue Engineering,” Trans. Control. Rel. Soc., 38:74, 2011.

18. Hinds FM, Spicer PP, Shi M, Wong ME, Kasper FK and Mikos AG, “Development,

Characterisation and Optimisation of Poly(methylmethacrylate) Bone Cement Formulations for Application as a Space Maintainer in a Staged Strategy for Cranio-facial Bone Regeneration,” International Journal of Surgery, 9:537, 2011.

19. Meretoja VV, Dahlin RL, Kasper FK and Mikos AG, “Flow Perfusion Bioreactor for Bone

and Cartilage Tissue Engineering,” Trans. Soc. Biomater., 33:406, 2011. 20. Buchanan RM, Murphy MB, Yoon DM, Henslee AM, Nair M, Kasper FK, Simmons PJ,

Mikos AG, Ferrari M and Tasciotti E, “Calcium Alginate Porogens for the Development of an Injectable Paste to Treat Traumatic Fractures,” Trans. Soc. Biomater., 33:80, 2011.

21. Shi M, Kretlow JD, Young S, Wong ME, Mikos AG and Kasper FK, “Gelatin Microparticle-

incorporating Poly(methyl methacrylate) Constructs for Craniofacial Tissue Engineering,” Trans. Control. Rel. Soc., 37:820, 2010.

22. Smid C, Buchanan R, Murphy M, Blashki D, Fan D, De Rosa E, Yoon DM, Kasper FK, Liu

X, Jones H, Noble P, Weiner B, Simmons P, Mikos AG, Ferrari M and Tasciotti E, “An Injectable Scaffold Exhibiting Staggered Bioactive Release through Multi-functional Components for Bone Fracture Repair,” Trans. Control. Rel. Soc., 37:210, 2010.


23. Shi M, Kretlow JD, Young S, Wong ME, Kasper FK and Mikos AG, “Gelatin Microparticle-incorporating Poly(methyl methacrylate) Constructs for Craniofacial Tissue Engineering,” Trans. Soc. Biomater., 32:572, 2010.

24. Shi M, Kretlow JD, Spicer P, Nguyen A, Young S, Wong ME, Kasper FK and Mikos AG,

“Emerging Controlled Release Approaches for Bone Tissue Engineering,” Abstr. Eur. Symp. Contr. Drug Deliv., 11:67, 2010.

25. Martins AM, Pham QP, Malafaya PB, Sousa RA, Gomes ME, Kasper FK, Reis RL and

Mikos AG, “The Role of Lipase and α-amylase in both the Degradation of Starch/Polycaprolactone Fiber Meshes and the Osteogenic Differentiation of Rat Marrow Stromal Cells,” Trans. World Biomater. Congr., 8:1931, 2008.

26. Liao J, Guo X, Pham QP, Kasper FK and Mikos AG, “Effect of Transforming Growth

Factor-β1 on Chondrogenic Differentiation of Mesenchymal Stem Cells Cultured on Biodegradable Microfiber Scaffolds,” Trans. World Biomater. Congr., 8:1228, 2008.

27. Mikos AG and Kasper FK, “Tissue Engineering and Its Future Perspective,” Trans. World

Biomater. Congr., 8:1226, 2008. 28. Kasper FK, Young S., Tanahashi K, Barry MA, Tabata T, Jansen JA and Mikos AG,

“Evaluation of Bone Regeneration by DNA Release from Composites of Oligo(Poly(ethylene glycol) fumarate) and Cationized Gelatin Microspheres in a Critical-sized Calvarial Defect,” Trans. Control. Rel. Soc., 33:525, 2006.

29. Kasper FK, Jerkins E, Tanahashi K, Barry MA, Tabata Y and Mikos AG, “Characterization

of DNA Release from Composites of Oligo(poly(ethylene glycol) fumarate) and Cationized Gelatin Microspheres In Vitro,” Trans. Soc. Biomater., 29:28, 2006.

30. Kasper FK, Kushibiki T, Kimura Y, Mikos AG and Tabata Y, “In Vivo Release of Plasmid

DNA from Composites of Oligo(poly(ethylene glycol) fumarate) and Cationized Gelatin Microspheres,” Proceed. Intern. Symp. Control. Rel. Bioact. Mater., 32:605, 2005.

31. Kasper FK, Seidlits SK, Barry MA and Mikos AG, “In Vitro Release of Plasmid DNA from

Oligo(poly(ethylene glycol) fumarate) Hydrogels,” Proceed. Intern. Symp. Control. Rel. Bioact. Mater., 32:585, 2005.

32. Mikos AG, Hedberg EL, Jo S, Kasper FK, Shin H and Temenoff JS, “Injectable

Biodegradable Hydrogels for Tissue Engineering,” Proceed. Intern. Symp. Control. Rel. Bioact. Mater., 29:83, 2002.

c) Invited Presentations at Other Universities and at Professional Meetings (*Presenter)

1. “Translational Biomaterial-based Approach for Craniofacial Tissue Regeneration,” 2013 Annual Meeting of the American Association of Blood Banks, Denver, Colorado. (October 14, 2013) With Kasper FK*.

2. “Projected Needs for Characterization of Hydrogels for Tissue Engineering,” ASTM

International Workshop on “Standards and Measurements for Tissue Engineering


Scaffolds: What Do We Have? What Do We Need?,” Indianapolis, Indiana. (May 21, 2013) With Kasper FK* and Mikos AG.

3. “Translational Biomaterial-based Approaches for Tissue Engineering,” Biomaterials Day:

Putting the Pieces Together: Students, Researchers, Biomaterials and Commercialization, University of South Dakota, Sioux Falls, South Dakota. (May 8, 2013) With Kasper FK*. (Keynote Talk)

4. “Osteogenic Differentiation of Mesenchymal Stem Cells on Demineralized and Devitalized

Biodegradable Polymer and Extracellular Matrix Hybrid Constructs,” 2013 Annual Meeting of the Society For Biomaterials, Boston, Massachusetts. (April 10-13, 2013) With Kasper FK*. (Plenary Session - Young Investigator Award Talk)

5. “Life Inside the Hedges: Leveraging the Rice Environment for Success” Rice University

Century Scholars Seminar Series, Houston, Texas. (March 12, 2012) With Kasper FK*. 6. “Translational Biomaterials-based Approaches for Bone Tissue Engineering,” 20th Annual

Advances in Tissue Engineering Short Course, Rice University, Houston, Texas. (August 11, 2012) with Kasper FK*.

7. “Life Inside the Hedges: Leveraging the Rice Environment for Success” Rice University

Office of Graduate & Postdoctoral Studies Seminar Series, “How to Succeed as a Graduate Student at Rice and Beyond,” Houston, Texas. (March 29, 2012) With Kasper FK*.

8. “Harnessing Nanotechnology in Approaches for Tissue Engineering” 2nd International

Conference on Nanotechnology at the Bio-Medical Interface (NANOBIO 2012), Kochi, Kerala, India. (February 21-23, 2012) With Kasper FK and Mikos AG* (Keynote Lecture)

9. “Leveraging Biomaterials in Approaches for Tissue Engineering,” TERMIS-North America

Annual Conference and Exposition, Houston, Texas. (December 11-14, 2011) With Kasper FK*. (Plenary Session - Young Investigator Award Talk)

10. “Promise and Pitfalls of Tissue Engineering Circa 2011,” TERMIS-North America Annual

Conference and Exposition, “Regenerative Medicine’s Challenge to Cure” Workshop, Houston, Texas. (December 11-14, 2011) With Kasper FK*.


Tissue Engineering,” DSM, Geleen, The Netherlands. (October 18, 2011) With Kasper FK*.


Tissue Engineering,” Department of Biomaterials, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands. (October 17, 2011) With Kasper FK*.


Tissue Engineering,” Bone-Tec 2011, Hannover, Germany. (October 12-15, 2011) With Kasper FK*. (Keynote Lecture)


14. “Development of a Staged Approach for Craniofacial Bone Regeneration,” The Rolanette and Berdon Lawrence Bone Disease Program of Texas Bone Research Club, Houston, Texas. (September 14, 2011) With Kasper FK*.

15. “Advancing Biomaterials Strategies for Translational Craniofacial Bone Tissue

Engineering,” Kyoto University Global COE “Center for Frontier Medicine” International Symposium, Awaji, Japan. (September 9-10, 2011) With Shi M, Spicer PP, Kretlow JD, Demian N, Wong ME, Mikos AG and Kasper FK*. (Plenary Lecture)

16. “Regulatory Considerations in the Development of Approaches for Craniofacial Tissue

Engineering,” 19th Annual Advances in Tissue Engineering Short Course, Rice University, Houston, Texas. (August 12, 2011) with Kasper FK*.

17. “Harnessing Inflammation in Tissue Engineering,” 19th Annual Advances in Tissue

Engineering Short Course, Rice University, Houston, Texas. (August 13, 2011) with Kasper FK*.

18. “Antibiotic-releasing Porous Poly(methyl methacrylate) Space Maintainers for Craniofacial

Tissue Engineering,” 9th International Symposium on Frontiers in Biomedical Polymers, Funchal, Portugal. (May 9-12, 2011) With Spicer PP, Shi M, Kretlow JD, Henslee AM, Young S, Demian N, Jansen JA, Wong ME, Kasper FK* and Mikos AG. (Keynote Lecture)

19. “Defining the Engineering in Tissue Engineering,” 36th Annual Meeting of the Society For

Biomaterials, Orlando, Florida. (April 13-16, 2011) With Dahlin RL, Kasper FK and Mikos AG*.

20. “Novel Materials and Approaches for the Regeneration of Bone and Cartilage,”

Symposium en Génie Tissulaire, Les Conférences du Centre LOEX de l’Université Laval, Québec City, Canada. (March 13, 2011) With Kasper FK*. (Keynote Lecture)

21. “Anticipation of Regulatory Pathways in Strategies for Bone Regeneration,” 2010 Armed

Forces Institute of Regenerative Medicine Interim Meeting, Washington DC. (December 9-10, 2010) With Kasper FK*, Wong ME and Mikos AG.

22. “Leveraging Clinical Products and Harnessing Inflammation in Strategies for Bone

Regeneration,” TERMIS-North America Annual Conference and Exposition Pre-conference Workshop, Orlando, Florida. (December 5, 2010) With Kasper FK*, Wong ME and Mikos AG.

23. “Evolving Approaches Harnessing Biomaterials for Bone Tissue Engineering,” 16th

International Biomedical Science & Technology Symposium (BIOMED 2010), Beşiktaş, İstanbul, Turkey. (September 29 - October 2, 2010) With Kasper FK* and Mikos AG. (Keynote Lecture)

24. “Advancing Translational Approaches for Craniofacial Reconstruction,” Advanced

Technology Applications for Combat Casualty Care 2010, St. Pete Beach, Florida. (August 16-19, 2010) With Kasper FK*. (on behalf of the Craniofacial Reconstruction Program of the Wake Forest-Pittsburgh Consortium of the Armed Forces Institute of Regenerative Medicine)


25. “Nanocomposite Scaffolds for Tissue Engineering,” 18th Annual Advances in Tissue Engineering Short Course, Rice University, Houston, Texas. (August 14, 2010) With Kasper FK*.

26. “Harnessing Inflammation in Strategies for Bone Tissue Engineering,” 39th Annual Meeting

of the American Aging Association, Portland, Oregon. (June 4-7, 2010) With Kasper FK*, Mountziaris PM, Tzouanas SN and Mikos AG.

27. “Emerging Biomaterial Approaches for Bone Tissue Engineering,” 2009 AIChE Annual

Meeting, Nashville, Tennessee. (November 8-13, 2009) With Kasper FK* and Mikos AG. 28. “Advancing Biomaterials Strategies for Bone Tissue Engineering,” Bone-Tec 2009,

Hannover, Germany. (October 8-11, 2009) With Kasper FK*. (Keynote Lecture) 29. “Synthetic Scaffolds for Bone Tissue Engineering,” 2nd Tissue Engineering and

Regenerative Medicine International Society World Congress, Seoul, Korea. (August 31-September 3, 2009) With Kasper FK* and Mikos AG. (Keynote Lecture)

30. “Nanocomposite Scaffolds for Tissue Engineering,” 17th Annual Advances in Tissue

Engineering Short Course, Rice University, Houston, Texas. (August 15, 2009) With Kasper FK*.

31. “Tissue Engineering Education,” 34th Annual Meeting of the Society for Biomaterials, San

Antonio, Texas. (April 25, 2009) With Kasper FK and Mikos AG*. 32. “Degradable Polymer Networks for Bone Tissue Engineering,” United States Army Institute

of Surgical Research, Fort Sam Houston, Texas. (April 21, 2009) With Kasper FK*. 33. “Generation of Bone Tissue Engineering Constructs Using a Flow Perfusion Bioreactor,”

26th Annual Houston Conference on Biomedical Engineering Research, Houston, Texas. (March 19-20, 2009) With Kasper FK*. (Keynote Lecture)

34. “Animal Models for Evaluation of Bone Grafting Materials in the Craniofacial Complex,”

2009 Armed Forces Institute of Regenerative Medicine “All Hands” Meeting, St. Pete Beach, Florida. (January 13-16, 2009) With Kasper FK*, Kretlow JD, Wong ME, and Mikos AG.

35. “Bioactive Extracellular Matrix Constructs for Osteogenic Differentiation of Marrow Stromal

Cells,” BioInterface 2008, Minneapolis, Minnesota. (October 27-29, 2008) With Kasper FK* and Mikos AG.

36. “Biomimetic Strategies for Tissue Engineering of Bone,” 3rd Marie Curie Cutting Edge

InVENTS Conference on Biomineralisation of Polymeric Materials, Bioactive Biomaterials and Biomimetic Methodologies, Madeira, Portugal. (June 4, 2007) With Kasper FK* and Mikos AG.

37. “Drug Delivery and Bioreactor Strategies in Tissue Engineering,” 1st Summer School of the

European Chapter of the Tissue Engineering and Regenerative Medicine International Society: Key Elements of Tissue Engineering, Madeira, Portugal. (June 3, 2007) With Kasper FK* and Mikos AG.


38. “Tissue Engineering Scaffolds: The Principles and the Practice,” 4th Annual Cell-based Therapies and Tissue Engineering Short Course, Case Western Reserve University, Cleveland, OH. (June 2, 2005) With Kasper FK* and Mikos AG.

d) Service as a Panelist or Discussant at Professional Meetings

1. Invited Panelist, “Cell and Tissue Culture Expert Panel,” University Space Research Association, Houston, Texas, 2013.

2. Panelist, “Student and Young Investigator Section Career Session,” Tissue Engineering and Regenerative Medicine International Society (TERMIS) World Congress, Vienna, Austria, 2012.

3. Panel Co-chair, “Development of Standards in Tissue Engineering and Regenerative Medicine,” Annual Meeting of the Tissue Engineering and Regenerative Medicine International Society (TERMIS) North America, Orlando, Florida, 2010.

e) Table Clinic Presentations None

G. Non-refereed Publications None

H. Continuing Education Courses Presented None

I. Other Teaching Experience: UTHealth Course Director: Cell/Developmental Biology (DBPG1106) Fall 2014 This graduate course reviews principles of molecular biology and provides a basic understanding of genetics and cytogenetics, and a detailed knowledge of development of the craniofacial complex, including formation of the face and the bones of the skull. A review of cell structure and reproduction is included, as well as a session on special techniques the student is likely to encounter in their studies and/or research. Course Director: Oral Biology: Development, Structure and Function of Oral Tissues (DBPG1110) Fall 2014 This graduate course provides an overview of the developmental anatomy, light and ultrastructural microscopic features, biochemistry, and functional properties of oral tissues. In particular, emphasis is placed on developing and adult mineralized tissues of enamel, dentin, bone, and cementum as well as pulp, periodontium, oral mucosa, and salivary glands.


Advanced instruction includes information about current research advances (basic and translational) within each of the topic areas. Rice University Co-instructor: Biomaterials (BIOE 370) Fall 2008 – 2013 This undergraduate course introduces both basic materials science and biological concepts with an emphasis on application of these basic principles to understanding the interactions between materials and biological systems. Co-instructor: Tissue Engineering (BIOE 620) Spring 2009 – 2013 This graduate course presents strategies to regenerate metabolic organs and structural tissues with a particular emphasis on applying engineering principles toward scaffold design, bioactive factor delivery and cell transplantation approaches for tissue regeneration. Faculty Mentor: Introduction to Engineering Design (ENGI 120) Spring 2012 This undergraduate course introduces students to the engineering design process and requires them to apply it to solve meaningful problems drawn from local hospitals and medical facilities, local engineering companies, and international communities. Supported efforts of two teams both in and out of class. Guest Lecturer: Fundamental Concepts in Biology (BIOS 122) Fall/Spring 2008 – 2013 Presented lectures on biomaterials and tissue engineering to non-science major undergraduate students and wrote associated exam questions. Guest Lecturer: Advances in Bioengineering (BIOE 202) Spring 2007 – 2010, 2012 Presented lectures on biomaterials, controlled bioactive factor delivery, and on the societal and ethical implications of bioengineering to undergraduates majoring in science and engineering. Guest Lecturer: Spring 2010 Philosophical Challenges and Engineering Applications of Stem Cells (BIOE 220) Presented a lecture on the application of bone marrow-derived stem cell populations in musculoskeletal tissue engineering. Guest Lecturer: Foundations in Biotechnology (BIOE 577) Spring 2008 Presented an overview lecture regarding advanced approaches for orthopeadic tissue engineering to graduate students in bioengineering and the biosciences. Guest Lecturer: Introduction to Bioengineering (BIOE 551) Fall 2008 Presented an overview lecture regarding recent advances in biomaterial approaches for controlled drug delivery and orthopaedic tissue engineering to graduate students in engineering. Teaching Assistant: Advanced Bioengineering Lab (BIOE 441) January – December 2001 Supervisor: Ann Saterbak, Ph.D. Designed and developed a senior bioengineering lab module involving mechanical testing of chicken bones, skin and tendons using an Instron 5565 mechanical testing system, wrote the accompanying text, and assisted students in comprehension and completion of the lab module. Textbook Contributor March 2006 – July 2007


Composed text passages, chapter summaries, figures, and example problems in the preparation of the following undergraduate level biomaterials textbook: Temenoff JS and Mikos AG. Biomaterials: The Intersection of Biology and Materials Science. Pearson Prentice Hall, Upper Saddle River, NJ, 2008.

J. Patents

1. Mikos AG, Wong ME, Young SW, Kretlow JD, Shi M and Kasper FK, “Combined Space Maintenance and Bone Regeneration System for the Reconstruction of Large Osseous Defects,” PCT/US2011/021266, pending.

2. Mikos AG, Kasper FK, Ekenseair AK, Vo TN, Boere K.W.M. and Touchet TJ, “Injectable, Thermogelling Tissue Engineering Scaffolds Utilizing Polyamidoamines,” PCT/US2012/68810, pending.


F. Kurtis Kasper, PhD - School of Dentistry CV 12-2014... · CURRICULUM VITAE. December 8, 2014 ....

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Transcript of F. Kurtis Kasper, PhD - School of Dentistry CV 12-2014... · CURRICULUM VITAE. December 8, 2014 ....