Ezastatin ( The Art of Combination Therapy)
-
Upload
faris-salama -
Category
Health & Medicine
-
view
416 -
download
0
description
Transcript of Ezastatin ( The Art of Combination Therapy)
Coronary Artery Disease Risk
Coronary Artery Disease Risk
Are LDL-C Goals The Same For All Patients With Dyslipideamia?
Coronary Artery Disease RiskATP III modification
Debate
Can we achieve these goals with Statin mono therapy alone ?
At which Statin concentration ? Is it enough to achieve normal lipid
profile only ? what else ? What about increase exogenous
cholesterol absorption in diabetics?
Coronary Artery Disease RiskStatins monotherapy limitations
Coronary Artery Disease RiskStatins monotherapy limitations
Fill the unmet need in lipid lowering managementEzastatin
atorvastatin + ezetimibe
MANAGEMENT OF DIABETIC DYSLIPIDEMIA: RECENT ADVANCES IN COMBINATION THERAPY
Fill the unmet need in lipid lowering managementEzastatin
atorvastatin + ezetimibe
Fill the unmet need in lipid lowering managementEzastatin
atorvastatin + ezetimibe
Fill the unmet need in lipid lowering managementEzastatin
atorvastatin + ezetimibe
Fill the unmet need in lipid lowering managementEzastatin
atorvastatin + ezetimibe
Fill the unmet need in lipid lowering managementEzastatin
atorvastatin + ezetimibe
Fill the unmet need in lipid lowering managementEzastatin
atorvastatin + ezetimibe
Fill the unmet need in lipid lowering managementEzastatin
atorvastatin + ezetimibe
Fill the unmet need in lipid lowering managementEzastatin
atorvastatin + ezetimibe
Fill the unmet need in lipid lowering managementEzastatin
atorvastatin + ezetimibe
Fill the unmet need in lipid lowering managementEzastatin
atorvastatin + ezetimibe
Fill the unmet need in lipid lowering managementEzastatin
atorvastatin + ezetimibe
Fill the unmet need in lipid lowering managementEzastatin
atorvastatin + ezetimibe
Fill the unmet need in lipid lowering managementEzastatin
atorvastatin + ezetimibe
Fill the unmet need in lipid lowering managementEzastatin
atorvastatin + ezetimibe
Fill the unmet need in lipid lowering managementEzastatin
atorvastatin + ezetimibe
Fill the unmet need in lipid lowering managementEzastatin
atorvastatin + ezetimibe
Why Ezastatin
Ezastatin combines 10 mg ezetimibe with 40 mg atorvastatin
Marked improvement in lipid profile compared to plain Atorvastatin.
Reduction in Oxidized LDL, an effect not achieved by up-titration of statin dose.
Reduces cholesterol absorption specially in diabetic patients with CAD.
Ezastatin with 40 mg atorvastatin concentration to benefit from pleiotropic effects of atorvastatin.
Ezastatin reduces CIMT compared to standard and aggressive therapy.
Higher safety profile than maximizing atorvastatin dose to 80mg.
Ezastatinatorvastatin + ezetimibe
Fill the unmet need in lipid lowering management
THANK YOU
Thank YOU