Extragenital lichen answer

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Extragenital lichen sclerosus et atrophicus F. Peral Rubio, M.D. Department of Dermatology Complejo Hospitalario Universitario, Badajoz, Spain. www.dermatoblog.com

Transcript of Extragenital lichen answer

Page 1: Extragenital lichen answer

Extragenital lichen sclerosus et atrophicus

F. Peral Rubio, M.D.Department of Dermatology Complejo Hospitalario Universitario, Badajoz, Spain.

www.dermatoblog.com

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Extragenital lichen sclerosus et atrophicus

A 50-years-old women.The patient was referred to us for the assessment of lesions on the abdomen.

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Extragenital lichen sclerosus et atrophicus

Physical Examination:Hypopigmented, atrophic, 3cm to 6cm, thin plaques were present on the abdomen and inframammary area. Genital skin was without lesion.

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Extragenital lichen sclerosus et atrophicus

Skin Biopsy revealed:

Epidermal atrophy.Vacuolar alteration of dermo-epidermal junction.Sclerosis of the papillary dermis.

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Extragenital lichen sclerosus et atrophicus

Laboratory examinations:A complete blood count, liver, kidney, and thyroid function tests were normal. Antinuclear antibody and Borrelia burgdorferi serology was negative.

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Extragenital lichen sclerosus et atrophicus

Treatment of extragenital Lichen Sclerosus has been reported:

The first-line treatment for all types, is the use of superpotent topical glucocorticoids. Tacrolimus ointment not useful for patients with extragenital lichen sclerosus.Pulsed high-dose corticosteroids combined with low-dose methotrexate treatment in patients with refractory generalized extragenital lichen sclerosus.

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Extragenital lichen sclerosus et atrophicus

Other treatments:Narrowband UV-B phototherapy.Pulsed dye laser Topical and oral retinoids PUVA.UVA1 phototherapy.Antimalarials.

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Extragenital lichen sclerosus et atrophicus

In this case performed initially treated with topical glucocorticoids getting good response.

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Extragenital lichen sclerosus et atrophicus

F. Peral Rubio, M.D.Department of Dermatology Complejo Hospitalario Universitario, Badajoz, Spain.

www.dermatoblog.com