Excito Toxins

7/30/2019 Excito Toxins

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Excitotoxins


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The job of GABA(gamma-amino-n-

butyric acid) is tocalm brainfunctions

When glutamate is pumped into astrocytes (a major mechanism for terminating itsexcitatory action), the glutamate is converted into glutamine.

Glutamine is then released by the astrocytes, picked up by glutamate-neurons, storedin vesicles, and converted back to glutamate as needed.

Excessive free radicals can prevent glutamate uptake by astrocytes.


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http://www.youtube.com/watch?v=90cj4NX87Yk&feature=related
http://www.youtube.com/watch?v=90cj4NX87Yk&feature=relatedhttp://www.youtube.com/watch?v=90cj4NX87Yk&feature=related


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Excitotoxicity can cause these tight junctures to open up and allow moleculesthrough. Technically this is known as "paracellular transport" but morecommonly it is known as "leaky gut".

Other tissues such as bladder and kidney can be leaky like this too.


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When the glutamate receptors over-stimulate in response , effectssuch as these can be experienced.

Brain headaches (including migraines), irritability, aggression,depression, confusion, uncontrollable cravings, seizures

Esophagus reflux, indigestion

Bowel irritable bowel, diarrhea

Nerves tingling sensations, ringing in the ears, visual sensitivity,changed sense of taste or smell

Heart cardiac arrhythmia and cardio artery spasm (heart attacks, bothcan be fatal)

There is growingevidence that theexcitotoxic mechanism

plays a major role incardiac disease.


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Also characteristic of MSG exposure is an increase in insulin release from the pancreas.

The pancreas contains numerous glutamate type receptors, andglutamate in the diet can induce as much as a threefold increase in insulin releasefrom the pancreas.

In addition, experiments in animals have demonstrated that MSG can induceinsulin resistance, exactly as we see in type 2 diabetes in humans.


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Excess glutamate impairs a baby's nervous system. It can contribute todevelopmental delays and lead to juvenile obesity or (SIDS).

Excitotoxins themselves, can cause the generation of numerous amounts of free radicals.

A particularly deadly combination occurs in young athletes: Low magnesium intake, highcalcium intake, low intake of omega-3 fatty acids and excitotoxins in food additives.

When magnesium stores are low, as we see in athletes, the glutamate receptors are sosensitive that even low levels of these excitotoxins can result in cardiac arrhythmiasand death.

One characteristic of the obesity induced byexcitotoxins is that itdoesnt appear todepend on food intake.


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In unprocessed whole foods, glutamic acid and aspartic acid are not freeamino acids. They are bound together with other amino acids in complex

proteins.

These get digested and absorbed as combined amino acids. They get broken down in the liver and released at very low levels the body can dealwith.

Hydrolysis is used during processing to break down proteins and starches into aminoacids, simple sugars, and fatty acids.

Hydrolysis can be achieved using chemicals,enzymes, heat, and other techniques.

Processed FoodsSoybeansCitric acid

'Edible' films and coatings applied to foods


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Food science has explored and refined a variety of processes to convert whole

foods into basic materials.

These materials are manipulated, combined, and added to foods in ways thatmeet performance and cost requirements.

When an excess of food-borne excitotoxins, such as MSG , hydrolyzed proteinsoy protein isolate and concentrate , natural flavoring , sodium caseinateand aspartate from aspartame , are consumed, glutamate receptors are over-stimulated, producing cardiac arrhythmias.

High consumption of aspartame adds an additional cardiacmuscle toxin: methanol.

A number of studies have shown that consuming aspartameand MSG (and similar excitotoxins) together greatlymagnifies the toxicity.


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Ingredients are engineered to achieve attractive taste, texture, appearance, and shelf life characteristics.

Glutamate or aspartame combined with colorsfound in snack foods were significantly moreneurotoxic than any of the chemicals alone.

Heavy metals cause glutamate to actmore strongly towards neuron death.

Aspartate is a component of aspartame -- the artificialsweetener known as Equal, NutraSweet andAminoSweet.

It's in diet sodas, sugar-free drink mixes, and all kinds of low-calorie packaged products.

Soft drink companies put their productscontaining aspartame in containersmade of aluminum. When aluminum --a known neurotoxin -- is combined withaspartame, the results are multiplied.


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Some Products that Contain Aspartame

Sugar-free cough syrups and cough drops could contain Aspartame

As the three cornered molecule Aspartame is metabolized it releases methylalcohol, plus phenylalanine and aspartic acid, both neurotoxins.

Aspartame's three components are: phenylalanine, which makes up 50 percent of the chemical weight; aspartic acid, which makes up 40 percent;and methanol (wood alcohol), which makes up 10 percent.

Carbonatedsoft drinks

Somevitamins

Frozendesserts

Yogurt Puddingsand fillings

Powdereddrink mixes

Chewinggum

Confections Gelatins Dessertmixes

Phenylalanine is an amino acid normally found in the brain. Human testing has shown phenylalanine levels in the blood are increased significantly in those who chronically useaspartame.

Excessive levels of phenylalanine in the brain can cause the levels of serotonin to decrease,which can lead to depression, schizophrenia and make one more susceptible to seizures.


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Aspartame May Speed Up the Process of Alzheimer's:Dr. H.J. Roberts, the foremost medical authority on aspartame,

believes that aspartame is partially responsible for the widespreadepidemic of Alzheimers, because it speeds up the process.This is likely because as other studies have shown aspartame cancause holes in the brains of rats.

Aspartame May Contribute to Parkinson's Disease:

According to Dr. Blaylock, excitotoxins may be a contributing factor inthe development of to Parkinsons disease.Excitotoxins, excessively stimulate the brain cells, which thengenerate free radicals causing cell injury and even death.

Some individuals (those who eat a diet low in nutrients andantioxidants) have cellular defense enzymes that are either immature or defective, and are unable to protect the brain cellsfrom excitotoxins.


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The methanol from breaking down aspartame can break down in your body as formaldehyde.

In the body, methanol is oxidated to formaldehyde and formic acid; bothof these metabolites are toxic.This oxidation occurs when methanol reaches 30 C.

The Environmental Protection Agency defines safe consumption of methanol as no more than 7.8 milligrams per day.

One can of diet sodacontains almost16 milligrams of methanol.

Over four billion gallons of diet sodas are sold per year .

The Food and Drug Administration (FDA) has received morecomplaints about aspartame than any other ingredient to date.


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Dr. H.J. Roberts, MD, stated after treating hundreds of aspartame reactors:the optic nerve swelling, retinal degeneration, and visual

impairment associated with heavy aspartame use is identicalto the pathology observed in recorded cases of methanoltoxicity from drinking wood alcohol throughout the days of

prohibition.

More Dangers of Methanol PoisoningIt has been demonstrated that formaldehyde formation fromaspartame ingestion is very common and it accumulateswithin the cell.It reacts with cellular proteins (mostly enzymes) and DNA(both mitochondrial and nuclear).

The fact that it accumulates with each dose, indicates graveconsequences among those who consume diet drinks andfoodstuffs on a daily basis.


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Military Warns Pilots About Aspartame:

Articles warned pilots about the many dangers of aspartame including the

cumulative deleterious effects of methanol.

The articles note that the ingestion of aspartame can make pilots more susceptibleto seizures and vertigo.

National Business Aircraft Association Digest (NBAA Digest 1993)Aviation Medical Bulletin (1988)

The Aviation Consumer (1988)Canadian General Aviation News (1990)Pacific Flyer (1988), General Aviation News (1989)Aviation Safety Digest (1989), and Plane and Pilot (1990)

Recently, a hotline was set up for pilots suffering from acute reactions to

aspartame ingestion.Over 600 pilots have reported symptoms including some who have reportedsuffering grand mal seizures in the cockpit due to aspartame.

Reported by the Aspartame Consumer Safety Network


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Hypothalamus

Microscopic photograph: shows normal brain area called the arcuate nucleus.

Photograph at right shows same area after exposure to MSG at 1 g/kg. White areas are dead brain cells resulting from the MSG exposure

As early as 1976, it was shown that aspartame feeding in mice could producelesions in the hypothalamus of newborns. These are lesions (injuries) that can

be seen through an ordinary light microscope.

Exposure to highintakes of excitotoxins, can alter the development of the hypothalamus,leading to sexual mal-development andendocrine problemsthat will appear later in life.


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Neuroscientist Dr. John Olney showed that one of the main ingredients in aspartame,aspartic acid, caused damage to the brains of infant mice. These findings have beenconfirmed in a similar study.

In an analysis of 166 articles published in medical journals from 1980 to 1985, Dr.Ralph G. Walton, a professor of psychiatry at Northeastern Ohio Universities Collegeof Medicine, found that 100 percent of the seventy-four studies financed by theindustry attested to the sweeteners safety.

Although of the ninety-two independently funded articles, 91 percent indentifiedadverse health reactions.


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Any time a cell's energy is reduced it becomesdramatically more sensitive to glutamate.Even normal levels of glutamate become excitotoxicwhen cell energy is low.

Keeping a normal blood sugar level is critical to brain function and excitotoxin protection.

During excitotoxicity, ATP production may bereduced, stopped or even reversed.

Several studies have shown thatthe levels consumed by our youthequal those that cause damage inexperimental animals.

Also, humans are 5X moresensitive to these toxins than anyanimal.

Consuming a meal or drink containing MSG can elevateglutamate in the blood by 20x.

Remember: By foodindustry definition, allMSG is "naturallyoccurring." "Natural"doesn't mean "safe.""Natural" only meansthat the ingredientstarted out in nature,like arsenic andhydrochloric acid.


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MSG-exposed animals prefer carbohydrates and sugars over protein-rich foods.A diet low in carbohydrates allows MSG to do its worst damage

Glutamic acid found in unadulterated protein does not causeadverse reactions.

To cause adverse reactions, the glutamic acid must have been

processed/manufactured or come from protein that has been fermented.

Also, when aspartameis paired with carbs, itcauses your brain toslow down its

production of serotonin, leading todepression andinsomnia.

MSG takes the flavors of any foodand enhances them to the max,then uses its addictive qualities tomake sure the customer keepscoming back for more.


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What many dont know, is that more than 40 different ingredients containthe chemical in monosodium glutamate (processed free glutamic acid).

The following list of ingredients has been compiled over the last 20 years fromconsumers reports of adverse reactions and information provided bymanufacturers and food technologists.

Names of ingredients that always contain processed glutamic acid :

Glutamic acid (E

620)

Monoammonium

glutamate (E 624)

Any hydrolyzed

protein

Gelatin

Glutamate (E 620) Magnesiumglutamate (E 625)

Anythinghydrolyzed

Yeast food

Monosodiumglutamate (E 621)

Natrium glutamate Textured protein Yeast nutrient

Calcium glutamate(E 622)

Calcium caseinate Ajinomoto Autolyzed yeast

Calcium glutamate(E 623)

Sodium caseinate Vestin Yeast extract


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When soy extracts are produced through hydrolysis; glutamic acid is released andconcentrated.

Names of ingredients that often contain or produce processed free glutamic acid:

Pectin (E 330) Soy sauceextract

Soy proteinconcentrate

Stock/ Broth Any flavors or flavoring

Protease Soy proteinisolate

Any proteinfortified

Bouillon Anything ultra-pasteurized

Malt extract Whey protein Seasonings CaramelFlavoring(coloring)

Anythingenzymemodified

Soy sauce Whey proteinconcentrate

Barley malt Carrageenan(E 407)

Anythingcontainingenzymes

Soy protein Whey proteinisolate

Citric acid (E330)- whenprocessedfrom corn

Maltodextrin Anythingfermented

The following ingredients work synergistically with MSG to enhance flavor.If they are present for flavoring purposes, so is MSG;Disodium 5-guanylate (E 627) Disodium 5-inosinate (E-631) Disodium 5'-ribonucleotides (E 635)


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These ingredients are suspected of containing or creating sufficient processed free glutamicacid.

Causes MSG-reaction triggers in HIGHLY SENSITIVE people:

Reduced fat milk (e.g.., skim milk; 1% milk; 2% milk) most things low fat or no fat andanything Enriched or Vitamin enriched.

Low fat and no fat milk products (ice cream, cheese, yogurt, milk, cream, cream cheese,cottage cheese, etc.) often contain milk solids that contain MSG and/or contain carrageenan,guar gum, and/or locust bean gum.

Drinks, candy, and chewing gum are potential sources of hidden MSG and/or aspartame,neotame. and AminoSweet (the new name for aspartame).

Neotame is relatively new. We have not seen it used widely in the United States.

Protein powders contain glutamic acid, which, invariably, will be processed free glutamicacid (MSG).

Milk powder Modified foodstarch

Corn syrup Corn starch

Brown ricesyrup

Lipolyzedbutter fat

Dextrose Rice syrup


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Humans concentrate MSG in their blood 5 times higher than mice from a

comparable dose, and maintain the higher blood level longer than mice.We concentrate MSG in our blood to a greater degree than any other knownanimal, including monkeys.

MSG could cause the hypothalamus to secrete excessive amounts of a

reproductive hormone (called luteinizing hormone) which is associated with anearly onset of puberty.

Numerous studies using immature mice have shown that LH, FSH and prolactin(the reproductive hormones), HGH (growth hormone), ACTH (adrenal regulatinghormone), and TSH (thyroid regulating hormone) were all decreased following

exposure to MSG.


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Is there anything that a person can take to block the absorption of MSG or glutamateas a defensive supplement?

Not necessarily to block it but, there are other amino acids that can't compete for glutamicacid absorption.So that may be one way to help reduce the rate at which it would be absorbed.

These would include leucine, isoleucine and lysine . They compete for the same carrier system, which would slow down absorption.

There are some good general rules to follow regarding amino acid therapy. 1) If you are considering using a specific amino acid, (such as glutamine, aspartic acid,cysteine, etc), document the need first.

2) Do not dose single amino acids on an empty stomach, especially those that are alsoexcitatory neurotransmitters.

3) Consider balancing single amino acid supplements with a broad-spectrum amino acidsupplement.


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There are a lot of things that act as glutamate receptor blockers:Like silymarin, curcumin (ingredient of turmeric), and ginkgo biloba .

Curcumin is very potent. It enhances bile flow as well as DNA repair enzymes.Most flavonoids reduce excitotoxicity.

Rosemary extract, green tea extract, ginger and oregano are also effectivenatural COX-2 inhibitors- reducing inflammation.

To enhance and ensure detoxification; milk thistle to help the liver eliminate alltoxins.


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The brain normally contains one of the highest concentrations of vitamin C in the body.The advantages of these antioxidants is that they can easily enter the blood brain

barrier and reach the brain cells where they are needed most.

The brain is very dependent on vitamin E & C for its protection. Vitamin Esuccinate is powerful at inhibiting excitotoxicity

Other antioxidant helpers are beta carotene, Vitamin K, Vitamin D, Vitamin A andthe mineral chromium.

They found combinations of B vitamins also block excitotoxicity.

Rechts Regulat: potent enzyme-rich fermented drink from Germany that has beenshown to break up abnormal proteins in blood and matrix.

An enzyme called "glutamate dehydrogenase" also helps neurons dispose of excessglutamate by converting glutamate to alpha-ketoglutarate (a Krebs' cycle fuel).

Glutamate dehydrogenase is activated by NADH, so taking the amount of NADH recommended will promote breakdown of glutamate excess.


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Anti-oxidants work best in combination and when use separately can have opposite,harmful, effects.

That is, when antioxidants, such as ascorbic acid and alpha tocopherol, becomeoxidized themselves, such as in the case of dehydroascorbic acid, they no longer protect, but rather act as free radicals themselves.

The same is true of alpha-tocopherol.

How to Help Protect Your Brain From Excitotoxins:

Magnesium has been discovered to help impede glutamates from overloadingglutamate receptors. Magnesium can block the NMDA glutamate type receptor.That's its natural function, so it significantly reduces toxicity.

Magnesium is vital to 300 biochemical functions within the body.

So it is important for overall health in addition to blocking glutamate sensors or channels from excitotoxin overload.

Magnesium content is high in green, leafy vegetables. It is also available in wholegrains and many beans and nuts.


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Omega 3 fatty acids also block excitotoxins while repairing cellular damage.Fish oils seem to be the best source of Omega 3 for this specific purpose,according to Dr. Russel Blaylock.

Selenium is another protector of glutamate receptors from excitotoxininvasion.Brazil nuts are considered a high source of selenium. Two or three Brazilnuts a day is considered sufficient for optimum selenium intake.

Zinc also helps obstruct the glutamate receptor channels from excessive

excitotoxin absorption.However, high levels of neuronal zinc may over activate thequisqualate/AMPA glutamate receptors, causing an excitotoxic action. Keepsupplementary zinc levels to 10-20 mg daily.

Red Clover Blocks Neurological Damage From MSG.It is an herb that is inexpensive and available as leaves for tea, in tinctures,

liquid extracts, and capsules.According to Barbara Minton's article, lab tests demonstrated a significantdecline in brain cell neuron damage when red clover's essential protectiveingredient was added.


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Your Health is Your Wealth so Spend it Wisely.

How You Can Protect Yourself:

Become aware of all unnecessary chemicalshidden in your foods. Be a food detective.Purify your diet as much as possible, and try toenjoy natural eating.

Educate yourself, your friends and family andanyone who will listen to you about the dangers

of excitotoxins.

The key is to eat food as close to nature as possible at all times.

Don't skip meals or practice "starvation dieting".


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Resources

Russell Blaylock, Excitotoxins: The Taste That KillsMike Adams, Grocery Warning How to recognize and avoid the groceries that cause cancer,diabetes, heart disease, high cholesterol, high blood pressure, and other common diseaseshttp://www.sailhome.org/Concerns/Excitotoxins.htmlhttp://www.bibliotecapleyades.net/salud/esp_salud23k.htmhttp://www.joyfulaging.com/Excitotoxins.htmhttp://www.conspiracyplanet.com/channel.cfm?channelid=63&contentid=5272&page=2http://chronicfatigue.about.com/b/2010/08/07/excitotoxins-food-in-fibromyalgia-chronic-fatigue-synwww.truthinlabeling.orghttp://www.321recipes.com/symptoms.htmlhttp://www.rejuvinstitute.com/excitotoxins-chemicals-destroy-healthhttp://www.mpwhi.com/excitotoxins_death_by_profit_margin.pdf http://thewellnesswarrior.blogspot.com/2010/08/sickeningly-sweet.htmlhttp://smart-drugs.net/ias-excitotoxins.htm
http://www.bibliotecapleyades.net/salud/esp_salud23k.htmhttp://www.joyfulaging.com/Excitotoxins.htmhttp://www.conspiracyplanet.com/channel.cfm?channelid=63&contentid=5272&page=2http://chronicfatigue.about.com/b/2010/08/07/excitotoxins-food-in-fibromyalgia-chronic-fatigue-syndrome.htmhttp://www.truthinlabeling.org/http://www.rejuvinstitute.com/excitotoxins-chemicals-destroy-healthhttp://thewellnesswarrior.blogspot.com/2010/08/sickeningly-sweet.htmlhttp://thewellnesswarrior.blogspot.com/2010/08/sickeningly-sweet.htmlhttp://www.rejuvinstitute.com/excitotoxins-chemicals-destroy-healthhttp://www.truthinlabeling.org/http://chronicfatigue.about.com/b/2010/08/07/excitotoxins-food-in-fibromyalgia-chronic-fatigue-syndrome.htmhttp://www.conspiracyplanet.com/channel.cfm?channelid=63&contentid=5272&page=2http://www.joyfulaging.com/Excitotoxins.htmhttp://www.bibliotecapleyades.net/salud/esp_salud23k.htm


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Some Pictureshttp://www.newmediaexplorer.org/sepp/aspartame-poison.jpghttp://www.granddistraction.com/wp-content/uploads/2009/04/excited_cells.jpghttp://pics.livejournal.com/food307/pic/000014t7http://www.msgexposed.com/wp-content/uploads/2009/04/doritos-flavors-msg.jpghttps://reader009.{domain}/reader009/html5/0425/5adf8bc91eac2/5adf8bdb83522.pnghttp://1.bp.blogspot.com/_SmqSa90BDlc/TEavXv9ydWI/AAAAAAAABRM/605CQvHk5IM/s1600/Aspartame-Sweetmisery.jpghttp://www.nature.com/nrd/journal/v7/n5/images/nrd2462-f1.jpghttps://reader009.{domain}/reader009/html5/0425/5adf8bc91eac2/5adf8bdc2af6a.pnghttp://medschool.creighton.edu/fileadmin/user/medicine/Departments/Pharm/Pharm_Images/MurrayResearch1.jpghttp://home.ix.netcom.com/~jdalton/two%20stage%20MS.jpghttp://home.ix.netcom.com/~jdalton/two%20stage%20MS.jpg

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