EWMA 2014 - EP448 BACTERIA AEROSOL SPREAD WITH DIFFERENT METHODS FOR WOUND DEBRIDEMENT
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Transcript of EWMA 2014 - EP448 BACTERIA AEROSOL SPREAD WITH DIFFERENT METHODS FOR WOUND DEBRIDEMENT
BACTERIA AEROSOL SPREAD WITH DIFFERENT METHODS FOR WOUND DEBRIDEMENT
HH Sönnergren, MD, LLB, S Polesie, MD, L Strömbeck, PhD, F Aldenborg, MD, PhD, BR Johansson, MD, PhD, J Faergemann, MD, PhD Department of Dermatology and Venereology Institute of Clinical Sciences at Sahlgrenska Academy, University of Gothenburg
Background • Debridement is essential in wound treatment to remove necrotic tissue and wound bacteria • Wound debridement may lead to the transmission of bacteria by aerosolization and cross-contamination of bacteria to other patients
Purpose The aims of the study were to in an ex vivo porcine wound model; 1) Determine the reduction of wound bacterial
load, and 2) Compare the amount of bacterial
aerosolization induced by debridement, using;
a) Cold steel curette, b) Plasma-mediated bipolar radiofrequency
ablation, or c) Hydro-debridement
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Methods
Porcine full thickness skin specimens
Artificial full thickness wounds cut out
Inoculated with S. aureus and incubated 24 hrs
Debrided with Plasma-ablation/Hydrosurgery/Curette
Bacteria-aerosol measured during debridement and Wound swabs pre/post
Fig 1. Artificial porcine wound.
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Results
• Only plasma-ablation significantly reduced the
wound bacterial load (P<0.0001).
• Hydro-debridement resulted in a significant bacterial aerosolization increase with up to 20 000% (P<0.001).
• Plasma-ablation and curette debridement did not increase bacterial aerosolization.
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Conclusions
This study shows that plasma-ablation is a promising wound debridement method which; • Effectively reduce the wound bed bacterial
load. • Do not increase the risk of bacterial
aerosolization.
Take home message The plasma-ablation method should be further evaluated in prospective clinical trials to evaluate the clinical antibacterial effect and the wound healing progression after treatment.
For additional information, please contact: Dr Henrik H Sönnergren Physician Department of Dermatology Gröna stråket 16 SE-41345, Gothenburg Sweden Phone: +46 703 347532 [email protected]
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