Etiology of Periodontal Diseases - II- Role of Calculus and Local Factors

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    Dental Plaque is the

    primary etiologic

    (initiating) factor ofperiodontal

    inflammation

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    Factors that facilitates and favor plaque

    retention and accumulation are LOCAL

    PREDISPOSING FACTORS

    Systemic conditions that alter the host

    response (i.e. make a person more susceptible

    to disease) are SYSTEMIC FACTORS. These willbe covered next lecture

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    Calculus

    Malocclusion

    Faulty restorationsOrthodontic therapy

    Self-inflected injuries

    Radiation therapy

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    A. Inorganic Components (7090 %):

    Calcium phosphate (76 %)Calcium carbonate (3 %)

    Magnesium phosphate and other metals

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    Inorganic component of calculus is madeof crystals with different chemical

    composition as follows:

    Hydroxyapatite 58 %

    Magnesium Whitlockite 21 % (more in

    posterior regions)

    Octacalcium phosphate 12 %

    Brushite 9 % (more in mandibular anterior

    regions)

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    B. Organic Components (10

    30 %):

    Carbohydrates (29%)

    Proteins (6

    8 %) Lipids (< 1%) such as fatty acids, neutral fats,

    cholesterol, and phospholipids

    Host cells and microorganisms

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    Same as subgingival calculus with some

    differences:

    Magnesium Whitlockite Brushite and Octacalcium phosphate

    calcium to phosphate ratio

    No salivary proteins (because its

    minerals are derived from the gingival

    fluid)

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    Four modes of attachment havebeen described:

    1. Attachment by means of an

    organic pellicle

    2. Mechanical locking intosurface irregularities such

    as resorption lacunae

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    Four modes of attachment have been

    described:

    3. Close adaptation of calculusundersurface to cementum surfaces

    4. Penetration of calculus bacteria intocementum

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    Plaque is hardened by precipitation of mineral

    salts

    It starts 1

    14 days of plaque formation

    It is mineralized 50% in 2 days and 60-90& in 12

    days

    Plaque concentrates calcium ions 2 -20 times

    its level in saliva

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    Heavy, moderate, slight and non-calculusformers due to:

    salivary pH salivary Ca++ bacterial protein and lipid concentration

    protein and urea in submandibular salivary

    gland secretions

    total salivary lipid levels

    individual inhibitory factors

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    Anti-calculus (anti-tarter) agents have been

    incorporated into some dentifrices to reduce

    the calculus formation

    These toothpastes may be help in heavy

    calculus formers

    However, plaque control measures are the

    cornerstone in reduction of calculus rate

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    Local rise in saturation of Ca++& P++ leadsto their precipitation. This precipitation is

    due to any of the following factors:

    pH

    Colloidal proteins in saliva bind Ca++& P++

    hydrolysis of organic phosphate due to theaction of phosphatase enzyme from

    desquamated epithelial cells and bacteria

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    Epitactic concept or heterogenous

    nucleation: Seeding agents (e.g.

    intercellular matrix) induce small foci ofcalcification that enlarge and coalesce to

    form calcified masses

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    Covered in previous lecture

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    Interfere with the oral hygiene

    measures

    They favor the multiplication of

    disease-associated

    microorganisms

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    Margins of restorations are

    better to be placed

    supragingivally as

    aesthetically as possible

    Dental restorations should be

    as smooth as possible whenthey are related to the gingiva

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    Over-contoured crowns andrestorations accumulate and

    retain more plaque than

    under-contoured restorations

    Integrity of proximal contacts

    prevents food impaction thatdeteriorates the periodontal

    healthplunger cusp

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    Malocclusion interferes with

    plaque control by the patient

    Prominent roots are associatedwith gingival recession and less

    adequate attached gingiva

    Gingival health deteriorates inmouth-breathers

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    The misuse of

    toothbrushes may resultin gingival abrasion and

    alteration of teeth

    shape

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    A. Localized tooth-relatedfactors that modify or

    predispose to gingival

    diseases/periodontitis:

    Tooth anatomic factors:

    Enamel Pearls

    Cervical Enamel

    Projections

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    Localized tooth-relatedfactors that modify or

    predispose to gingival

    diseases/periodontitis:

    Root fractures

    Cervical root resorption

    and cemental tears

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