ESSENTIAL PAIN MANAGEMENT CC BY-NC-SA: This work is licensed under a Creative Commons...

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ESSENTIAL PAIN MANAGEMENT CC BY-NC-SA: This work is licensed under a Creative Commons Attribution-NonCommerical-ShareAlike 3.0 License. 1.1

Transcript of ESSENTIAL PAIN MANAGEMENT CC BY-NC-SA: This work is licensed under a Creative Commons...

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ESSENTIAL PAIN MANAGEMENT

CC BY-NC-SA: This work is licensed under a Creative Commons Attribution-NonCommerical-ShareAlike 3.0 License.1.1

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EPM Aims

1.To improve understanding of pain2.To teach a simple framework for managing

pain3.To reduce pain management barriers

1.2

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Workshop Plan 1

• Pain basics– What is pain?– Why should we treat pain?– Classification of pain– Physiology and pathology– Pain treatment– Barriers to treatment

1.3

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Workshop Plan 2

• Practical pain management– Case discussions– Overcoming barriers

1.4

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Untreated Pain

1.5

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Untreated Pain

• Often hidden (not recognized)• Causes a lot of suffering• But … can often be treated simply and cheaply

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Approach to Pain

• Recognize• Assess• Treat

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Approach to PainR

• Recognize– Does the patient have pain?– Do other people know the patient has pain?

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Approach to PainA

• Assess– How severe is the pain?– What type of pain is it?– Are there other factors?

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Approach to PainT

• Treat– What non-drug treatments can I use?– What drug treatments can I use?

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IntroductionSummary

• At the end of this course, you will be able to:

1. Understand the importance of treating pain2. Recognize, assess and treat different types of

pain3. Identify and address barriers where you work

1.12

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What is Pain?

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What is Pain?Aims

• To define pain• To give examples of pain

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What is Pain?

• Group discussion

– Think of a patient / friend / relative who had pain.– How did the person describe the pain?– How was it treated?

2.3

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What is Pain?

• International Association for the Study of Pain– Pain is "an unpleasant sensory and emotional

experience associated with actual or potential tissue damage, or described in terms of such damage”.

• What does this mean?• Are there any other definitions?

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What is Pain?

• Unpleasant• Emotions are important• The cause is not always visible

• “Pain is what the patient says hurts.”

2.5

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Is this man feeling pain?2.6

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?2.7

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What is Pain?Summary

• Pain is an unpleasant sensory and emotional experience

• Pain is what the patient says hurts!

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Why Should We Treat Pain?

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Why Should We Treat Pain?Aims

• To understand the reasons for treating pain• To understand the benefits for the patient,

family and society

3.2

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Case 1

• Mr T is a 29-year-old man with a fast growing mouth cancer that has spread to his bones. He has severe face pain. He is expected to die within 6 months and the surgeons do not want to operate. He is married with two children, aged 11 and 8

• Why should we treat his pain?

3.3

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Case 2

• Mrs G is a 54-year-old woman who has just had a laparotomy for bowel obstruction. You see her on the surgical ward soon after the operation. She appears to be in pain.

• Why should we treat her pain?

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Why Pain Matters

• For the patient– Physical • Suffering, poor sleep, decreased appetite• Medical complications

(e.g. heart attack, pneumonia)– Psychological• Depression, anxiety

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Why Pain Matters

• For the family– Unable to function as part of the family

(e.g. as a father / mother)– Lost income

• For society– Greater health costs

(e.g. delayed hospital discharge)– Unable to contribute to the community

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Painful SCC (xeroderma pigmentosum)

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Advantages of Treating Pain

• For the patient– Fewer physical and psychological problems– Greater dignity (esp. cancer pain)

• For the family– Able to function as part of the family– Able to provide for family

• For society– Lower health costs

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?3.9

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Why Should We Treat Pain?Summary

• Treating pain is the “humane” thing to do!• Treating pain has many benefits– For the patient– For the family– For society

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Classification of Pain

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Classification of PainAims

• To classify types of pain• To understand that treatment depends on the

pain type

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Classification of Pain

• Not all pain is the same!• Three main questions:

1. How long has the patient had pain?2. What is the cause?3. What is the pain mechanism?

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Classification of Pain

Duration AcuteChronicAcute on chronic

Cause CancerNon-cancer

Mechanism Nociceptive (physiological)Neuropathic (pathological)

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Acute versus Chronic

• Acute– Pain of recent onset and probable limited

duration

• Chronic– Pain persisting beyond healing of injury– Often no identifiable cause– (Pain lasting for more than 3 months)

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Cancer versus Non-Cancer

• Cancer pain– Progressive– May be mixture of acute and chronic

• Non-cancer pain– Many different causes– Acute or chronic

Can you give examples?

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Invasive oral cancer

4.7

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Nociceptive Pain

• Obvious tissue injury or illness• “Physiological pain”• Description– Sharp ± dull– Well localised

Can you give examples?

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Neuropathic Pain

• Nervous system damage or abnormality• “Pathological pain”• Tissue injury may not be obvious• Description– Burning, shooting ± numbness, pins and needles– Not well localised

Can you give examples?

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Examples of Pain Types

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Acute Non-Cancer Pain

• Examples– Fracture, appendicitis

• Symptom of tissue injury or illness• Useful• Usually nociceptive• Occasionally neuropathic (e.g. sciatica)

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Chronic Non-Cancer Pain

• Examples– Headache, back pain

• Usually no obvious injury• Not useful• Complex, may be mixed nociceptive and

neuropathic• Does not respond to usual drug treatment

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Cancer Pain

• Examples– Oral cancer, uterine cervical cancer

• Features of acute and chronic pain– May be acute on chronic

• Often mixed nociceptive and neuropathic pain• Usually gets worse over time if untreated

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?4.14

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Classification of PainSummary

• Deciding on the type of pain is important– Acute / chronic– Cancer / non-cancer– Nociceptive / neuropathic

• Treatment depends on the pain type

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Pain Physiology and Pathology

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Pain Physiology and PathologyAims

• To understand normal pain physiology– Pain pathway – Factors affecting the pain signal

• To understand the basis of neuropathic pain(pathology)

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Nociception and Pain

• Nociception– How pain signals get from the site of injury to the

brain

• Pain perception– How we “feel” pain

• Nociception is not the same as pain!

5.3

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Is this man feeling pain?5.4

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PainWhat the patient says hurts.

What must be treated.

Injury

Beliefs/concerns about pain

Psychol. factorsanxiety/anger/depression

Cultural issuesLanguage, expectations

Other illnesses

Coping strategies

Social factorse.g. family, work

Nociception is not the same as pain!

Modified from Analgesic Expert Group. Therapeutic Guidelines 20075.5

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Physiology

• 4 steps:– Periphery– Spinal cord– Brain– Modulation

• We will look at each step

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Periphery

• Tissue injury• Release of chemicals• Stimulation of pain

receptors (nociceptors)

• Signal travels in Aδ or C nerve to spinal cord

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Spinal Cord

• Dorsal horn is the “first relay station”

• Aδ or C nerve synapses (connects) with second nerve

• Second nerve travels up opposite side of spinal cord

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Brain• Thalamus is the

“second relay station”

• Connections to many parts of the brain– Cortex– Limbic system– Brainstem

• Pain perception occurs in the cortex

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Modulation

• Descending pathway from brain to dorsal horn

• Usually decreases pain signal

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Why is pain physiology important?

• Many factors affect how we “feel” pain.– Psychological factors are very important.

• Different treatments work on different parts of the pathway.– More than one treatment may be needed.

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Neuropathic Pain

• “Pathological” pain• Abnormality of:– Peripheral nerves– Spinal cord or brain

• Needs to be treated differently

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Neuropathic Pain

• Peripheral– Damaged nerves (e.g. trauma, diabetes)– Abnormal firing of nerves

• Central– Changes in “wiring”– Abnormal firing– Loss of modulation

How do patients describe their pain?

5.13

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?5.14

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Pain Physiology and PathologySummary

• Many factors affect how we “feel” pain.• Different treatments work on different parts

of the pain pathway.• Neuropathic pain is “pathological” pain and

needs to be treated differently.

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Pain Treatment Overview

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Pain Treatment OverviewAims

• To discuss non-drug and drug treatments where you work

• To classify pain treatments

6.2

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Pain Treatment

• Group discussion

– What non-drug treatments are available where you work?

– What drug treatments are available where you work?

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Non-Drug Treatments

• Physical– Rest, ice, compression, elevation– Surgery– Acupuncture, massage, physiotherapy

• Psychological– Explanation– Reassurance– Counseling

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Placebo Treatment

• Group discussion

– What is placebo?– Is it helpful or unhelpful?

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Placebo Treatment

• Psychological factors are important.• If a placebo treatment works, this does not

mean the patient did not have pain or was telling lies!

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Drug Classification

• Simple analgesics– Paracetamol (acetaminophen)– Anti-inflammatory medicines– Aspirin, ibuprofen

• Opioids– Mild– Codeine

– Strong–Morphine, pethidine

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Drug Classification

• Other analgesics– Amitriptyline– Carbamazepine– Local anaesthetics– Ketamine– Tramadol– Clonidine– Entonox (N2O/O2)

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Treatments - Periphery

• Non-drug treatments– Rest, ice,

compression, elevation

• Anti-inflammatory medicines

• Local anaesthetics

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Treatments - Spinal Cord

• Non-drug treatments– Acupuncture,

massage

• Local anaesthetics• Opioids• Ketamine

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Treatments - Brain

• Non-drug treatments– Psychological

• Drug treatments– Paracetamol– Opioids– Amitriptyline– Clonidine

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?6.12

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Pain Treatment OverviewSummary

• Both non-drug and drug treatments are important.

• Different treatments work on different parts of the pain pathway.

• Analgesics can be classified into simple analgesics, opioids and other drugs.

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Pain Drugs

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Pain DrugsAims

• To summarise the major advantages and disadvantages of important drugs

• To discuss drug addiction

7.2

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Paracetamol (Acetaminophen)

• Advantages– Cheap, safe– Can be given orally or rectally– Good for:• Mild pain (by itself)• Mod-severe pain (with other drugs)

• Disadvantages– Liver damage in overdose

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Anti-Inflammatory Medicines

• Aspirin, ibuprofen• Advantages– Cheap, generally safe– Good for nociceptive pain• Best given regularly with paracetamol

• Disadvantages– Gastrointestinal and renal side effects

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Codeine

• Advantages– Cheap, safe– Good for mild-moderate acute nociceptive pain• Best given regularly with paracetamol

• Disadvantages– Constipation– Not good for chronic pain– Myths about addiction

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Opioids and Addiction

• Group discussion

– Do opioids cause addiction?– Would this stop you giving opioids to a patient

who has pain?

7.6

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Opioids and Addiction

• Pain is sometimes poorly treated because of concerns about addiction.

• Addiction is very rare in:– Acute pain– Cancer pain

• Addiction is more likely in chronic non-cancer pain.

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Morphine 1

• Advantages– Cheap, generally safe– Can be given orally, IV, IM, SC– Effective if given regularly– Good for:• Mod-severe acute nociceptive pain (e.g. post-op pain)• Chronic cancer pain

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Morphine 2

• Disadvantages– Constipation– Respiratory depression in high dose– Myths about addiction– Regulations about use

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Pethidine

• Advantages– Cheap– Can be given orally, IV, IM– Can be good for severe acute nociceptive pain

• Disadvantages– Must be given more often than morphine– Breakdown product (norpethidine) can cause

convulsions– Not good for chronic pain

7.10

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Amitriptyline• Increases descending inhibitory signals• Advantages– Cheap, safe in low dose– Good for neuropathic pain– Also treats depression, poor sleep

• Disadvantages– Anti-cholinergic side effects (glaucoma, urinary

retention)

7.11

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Anti-Epileptic Drugs

• Carbamazepine (Tegretol)• Sodium valproate (Epilim)• “Membrane stabilisers”– Reduce abnormal firing of nerves

• Good for neuropathic pain

7.12

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Entonox (N2O/O2)

• Advantages– Fast onset / fast offset– Good for:• Labour pains• Short painful procedures (e.g. dressing changes)

• Disadvantages– Need cylinder and mask

7.13

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Drug TreatmentsAcute noci mild

Acute nocisevere

Acute neuro

Chronic non-cancer

Chronic cancer

Paracetamol +++ ++ + + +NSAIMs ++ ++ + ± ±Codeine ++ + ±Morphine +++ ++ - +++Amitriptyline - - ++ ++ ++Carbamazepine - - ++ + +

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Pain DrugsSummary

• Pain can be treated with relatively cheap and safe drugs.

• Opioid addiction is rare in acute or cancer pain.

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Barriers to Pain Treatment

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Barriers to Pain TreatmentAims

• To understand some of the reasons why pain may not be treated adequately

• To think about some solutions

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Barriers to Pain Treatment

• Group Discussion– Pain is often not treated as well as it could be.

What are some of the reasons for this?• Patients• Drugs• Health workers• System issues

– What are the main barriers where you work?– What can be done about these barriers?

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Barriers to Pain TreatmentSummary

• There are many reasons why pain is not treated as well as it could be.

• Important barriers are attitudes, lack of staff and lack of drugs.

• How can YOU overcome these barriers where you work?

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Basic Approach to Pain Management

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Basic ApproachAims

• To give a simple framework for managing patients with pain

• To illustrate the use of this framework for different types of pain

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Approach to Pain

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Approach to Pain

• Recognize• Assess• Treat

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Approach to PainRecognize

• Does the patient have pain?– Ask– Look (frowning, moving easily, sweating?)

• Do other people know the patient has pain?– Other health workers– Patient’s family

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Approach to PainAssess

• Measure the severity– What is the pain score?• At rest• With movement

– How is the pain affecting the patient?• Can the patient move, cough?• Can the patient work?

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Measuring Pain

• Helps guide treatment• Methods– Verbal (e.g. mild, moderate, severe)– Numerical• 0 (no pain) to 10 (worst pain imaginable)

– Visual• Visual Analogue Scale (VAS)• “Faces” pain scale

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Visual Analogue Scale

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Faces Pain Scale

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Approach to PainAssess

• Make a pain diagnosis!– Acute or chronic?– Cancer or non-cancer?– Nociceptive or neuropathic?• Look for neuropathic features:

– Burning or shooting pain– Phantom limb pain– Other features (pins and needles, numbness)

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Approach to PainAssess

• Are there other factors?– Physical factors (other illnesses)– Psychological and social factors• Anger, anxiety, depression• Lack of social supports

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Approach to PainTreat

• Non-Drug Treatments– RICE• Rest, ice, compression, elevation of injuries

– Nursing care– Surgery, acupuncture, massage etc– Psychological• Explanation and reassurance• Input from social worker / pastor

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Approach to PainTreat

• Drug Treatments – Nociceptive Pain– Mild• Paracetamol (± NSAIM)

– Moderate• Paracetamol (± NSAIM) + codeine

– Severe• Paracetamol (± NSAIM) + morphine

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Approach to PainTreat

• Drug Treatments – Neuropathic Pain– Traditional drugs may not be as useful– Use other drugs early• Amitriptyline• Carbamazepine

• Don’t forget non-drug treatments

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Approach to PainExample 1

• Mr D is a 32-year-old man who caught his right hand in a piece of machinery at work and now has a large open wound with several broken bones.

• How would you manage his pain?

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Approach to PainExample 2

• Jon is an 8-year-old boy with probable appendicitis. He is in the Emergency Department and will have to wait several hours for an operation.

• How would you manage his pain?

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Approach to PainExample 3

• Miss B is a 24-year-old woman who has a two year history of severe headache. She was seen at the regional hospital 6 months ago and was told that there was “nothing wrong inside her head” and she was going to have to live with the pain.

• How would you manage her pain?

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Approach to PainExample 4

• Maria is a 12-year-old girl with burns to her chest and abdomen. She needs dressing changes every 2-3 days.

• How would you manage her pain?

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Approach to PainSummary

• Recognize• Assess– Measure severity– Make a pain diagnosis– Consider other factors

• Treat– Non-drug treatments– Drug treatments

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