Endocrinology: anatomy and physiology

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Jamie Ranse: Critical Care Education Coordinator, Staff Development Unit, ACT Health. Endocrinology anatomy and physiology

description

Presentation to participants undertaking the: Critical Care Transition Program at ACT Health, 2008

Transcript of Endocrinology: anatomy and physiology

Page 1: Endocrinology: anatomy and physiology

Jamie Ranse: Critical Care Education Coordinator, Staff Development Unit, ACT Health.

Endocrinology anatomy and physiology

Page 2: Endocrinology: anatomy and physiology

• Outline endocrine function

• Outline various functions of endocrine organs:

– Pituitary gland,

– Adrenal gland,

– Thyroid gland,

– Parathyroid glands, and

– Pancreatic function.

Overview

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Overview

What is the endocrine system?

• Complex system

• Coordinates and maintains a ‘steady state’

• Hormones activated by other hormones or neural impulses

• Regulated feedback system

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Overview

What are hormones?

• Chemical substances

• Transported though the blood to the target cells

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Endocrine organpituitary gland

• Gross anatomy

• Position

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Endocrine organpituitary gland

• Gross anatomy

• Position

• Divisions:– Adenohypophysis

• Pars tuberalis• Pars distalis

– Neurohypophysis• Neural lobe• Infundibular stalk• Median eminence

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Endocrine organpituitary gland

Common alterations in pathology (anterior pituitary)• Hypersecretion of growth hormone (Gigantism)• Hypersecreting ACTH (Cushing’s syndrome)

Common alterations in pathology (posterior pituitary)• ADH deficiency • Inappropriate ADH secretion

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Endocrine organadrenal gland

• Gross anatomy

• Position

• Layers

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Endocrine organadrenal gland

Adrenal cortex

• Adrenal cortical steroids (cortisol)

• Aldosterone

Adrenal medulla

• Adrenaline

• Noradrenaline

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Endocrine organadrenal gland

Common alterations in pathology• Adrenocortical insufficiency• Acute (addisionian) crisis

• Chronic deficiency• Adrenocortical excess

– Cushing’s syndrome– Cushing’s disease

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Endocrine organthyroid and parathyroid

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Endocrine organthyroid and parathyroid

Thyroid

• Thyroxine (T4)

• Triidothyronine (T3)

• Throcalcitonin

Parathyroid

• Parathormone

• Throcalcitonin

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Endocrine organthyroid and parathyroid

Common alterations in pathology

Thyroid• Hyperthyroidism (Graves disease)• Thyroid strom• Hypothyroidism

Parathyroid• Hyperparathyroidism• Hypoparathyroidism

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Endocrine organpancreas

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Endocrine organpancreas

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Summary

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Summary

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Summary

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Jamie Ranse: Critical Care Education Coordinator, Staff Development Unit, ACT Health.

Endocrinology anatomy and physiology