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Transcript of Endocrine function of hypothalamo-hypophyseal systemphysiology.lf2.cuni.cz/teaching/prezentace...
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Endocrine function of hypothalamo-hypophyseal
system
Matilda Meinshausen Group 1
Academic Year 2015/2016
Charles University of Prague 2nd Faculty of Medicine
Physiology
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Hypothalamus and hypophysis
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Hypothalamus and posterior pituitary
! Neural connections
! Hormones : ADH + oxytocin (neuropeptides)
! ADH = primarily associated w/ supraoptic ncl
! Oxytocin = primarily associated w/ paraventricular ncl
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Control of hormonal secretion
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Hypothalamus and anterior pituitary ! Secretes 6 peptide
hormones:
! Hypothalamus and ant. pituitary linked directly by hypothalamic-hypophyseal portal system
• TSH • FSH • LH • Growth
hormone • Prolactin • ACTH
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Anterior lobe hormones
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Hormone functions
Hormones
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1. Hormones synthesized by cell
bodies in the hypothalamus
Paraventricular nucleus
Neural Connection
Vascular Connection
Hypothalamic hormone control
secretion
Inhibitory Factors
Releasing Factors
Conducted through: Hypothalamic-hypophyseal
portal vessels
2. To Target Glands
Supraoptic nucleus
2. To General Circulation
1. Hormones synthesized by cells
in hypophysis
Nerve Fibers: Hypothalamic-hypophyseal tract
Overview
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References
! Constanzo, Linda (2011): Physiology. 5th edition, Lippincott Williams & Wilkins.
! Hall, John Edward, and Arthur C. Guyton. Guyton And Hall Textbook Of Medical Physiology. 12th ed. Philadelphia: W.B. Saunders Company, 2006. Print.
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Thank you for your attention!