Emergence of Community-Acquired Adenovirus Type 55 as a ...both S. pneumonia and Legionella...

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Online supplements are not copyedited prior to posting. ©2014 American College of Chest Physicians. Reproduction of this article is prohibited without written permission from the American College of Chest Physicians. See online for more details. DOI: 10.1378/chest.13-1186 CHEST 2014; 145(1):79-86 Emergence of Community-Acquired Adenovirus Type 55 as a Cause of Community-Onset Pneumonia Bin Cao, MD; Guo-Hong Huang, MD; Zeng-Hui Pu, MD; Jiu-Xin Qu, MD; Xiao-Min Yu, MD; Zhen Zhu, MD; Jian-Ping Dong, MD; Yan Gao, MD; Yong-Xiang Zhang, MD; Xiao-Hui Li, MD; Jian-Hua Liu, MD; Hong Wang, MD; Qian Xu, MD; Hui Li, MD; Wenbo Xu, MD; and Chen Wang, MD, FCCP e-Table 1. The microbiology of the total population (n=969) Pathogen identified n (%) At least one pathogen 393 (40.6) Respiratory viruses (RVs) 262 (27.0) IFV A 94 (9.7) ADV 48 (5.0) HRV 41 (4.2) HMPV 17 (1.8) PIV 1 16 (1.7) PIV 3 14 (1.5) PIV 2 11 (1.4) IFV B 6 (0.6) EV 5 (0.5) RSVA 5 (0.5) RSV B 4 (0.4) HCoV OC43/HKU1 4 (0.4) HCoV 229E/NL63 4 (0.4) PIV 4 1 (0.1) Atypical pathogens (APs) 172 (17.8) MP 168 (17.3) LP 4 (0.4) Bacteria* 47 (4.9) Mycobacterium tuberculosis 15 (1.5) Dual etiology 65 (6.7)

Transcript of Emergence of Community-Acquired Adenovirus Type 55 as a ...both S. pneumonia and Legionella...

Page 1: Emergence of Community-Acquired Adenovirus Type 55 as a ...both S. pneumonia and Legionella pneumophila. influenza virus (IFV) types A and B, human rhinovirus (HRV), adenovirus (ADV),

 

Online supplements are not copyedited prior to posting.

©2014 American College of Chest Physicians. Reproduction of this article is prohibited without written permission from the American College of Chest Physicians. See online for more details. DOI: 10.1378/chest.13-1186

CHEST 2014; 145(1):79-86

   

Emergence of Community-Acquired Adenovirus Type 55 as a Cause of Community-Onset Pneumonia Bin Cao, MD; Guo-Hong Huang, MD; Zeng-Hui Pu, MD; Jiu-Xin Qu, MD; Xiao-Min Yu, MD; Zhen Zhu, MD; Jian-Ping Dong, MD; Yan Gao, MD; Yong-Xiang Zhang, MD; Xiao-Hui Li, MD; Jian-Hua Liu, MD; Hong Wang, MD; Qian Xu, MD; Hui Li, MD; Wenbo Xu, MD; and Chen Wang, MD, FCCP e-Table 1. The microbiology of the total population (n=969)

Pathogen identified n (%)

At least one pathogen 393 (40.6)

Respiratory viruses (RVs) 262 (27.0)

IFV A 94 (9.7)

ADV 48 (5.0)

HRV 41 (4.2)

HMPV 17 (1.8)

PIV 1 16 (1.7)

PIV 3 14 (1.5)

PIV 2 11 (1.4)

IFV B 6 (0.6)

EV 5 (0.5)

RSVA 5 (0.5)

RSV B 4 (0.4)

HCoV OC43/HKU1 4 (0.4)

HCoV 229E/NL63 4 (0.4)

PIV 4 1 (0.1)

Atypical pathogens (APs) 172 (17.8)

MP 168 (17.3)

LP 4 (0.4)

Bacteria* 47 (4.9)

Mycobacterium tuberculosis 15 (1.5)

Dual etiology 65 (6.7)

Page 2: Emergence of Community-Acquired Adenovirus Type 55 as a ...both S. pneumonia and Legionella pneumophila. influenza virus (IFV) types A and B, human rhinovirus (HRV), adenovirus (ADV),

 

Online supplements are not copyedited prior to posting.

©2014 American College of Chest Physicians. Reproduction of this article is prohibited without written permission from the American College of Chest Physicians. See online for more details. DOI: 10.1378/chest.13-1186

CHEST 2014; 145(1):79-86

RVs + APs 34 (3.5)

IFV A + MP 10 (1.0)

HRV + MP 6 (0.6)

PIVs + MP 6 (0.6)

ADV + MP 4 (0.4)

HCoVs + MP 2 (0.2)

IFV B + MP 2 (0.2)

RSVs + MP 2 (0.2)

HMPV + MP 1 (0.1)

HRV + LP 3 (0.3)

RVs + bacteria 14 (1.4)

IFV A + bacteria 9 (0.9)

PIVs + bacteria 2 (0.2)

HMPV + bacteria 1 (0.1)

RVs + RVs 11 (1.1)

IFV A + HCoVs 2 (0.2)

IFV A + PIVs 2 (0.2)

HRV + PIVs 2 (0.2)

HMPV + PIVs 2 (0.2)

ADV + RSV A 1 (0.1)

ADV + PIVs 1 (0.1)

ADV + HCoVs 1 (0.1)

MP + bacteria 6 (0.6)

Data are expressed as n (%). * Note: 533 CAP patients were available to sputum culture. All 969 patients were tested with urine antigen tests for both S. pneumonia and Legionella pneumophila. influenza virus (IFV) types A and B, human rhinovirus (HRV), adenovirus (ADV), human metapneumovirus (hMPV), parainfluenza virus (PIV) types 1, 2, 3 and 4, enterovirus (EV), respiratory syncytial virus (RSV) types A and B, human coronavirus (HCoV) types 229E, NL63, OC43 and HKU1, Mycoplasma pneumoniae (MP) and Legionella pneumophila (LP).

Page 3: Emergence of Community-Acquired Adenovirus Type 55 as a ...both S. pneumonia and Legionella pneumophila. influenza virus (IFV) types A and B, human rhinovirus (HRV), adenovirus (ADV),

 

Online supplements are not copyedited prior to posting.

©2014 American College of Chest Physicians. Reproduction of this article is prohibited without written permission from the American College of Chest Physicians. See online for more details. DOI: 10.1378/chest.13-11886

CHEST 2014; 145(1):79-86

                                               

Page 4: Emergence of Community-Acquired Adenovirus Type 55 as a ...both S. pneumonia and Legionella pneumophila. influenza virus (IFV) types A and B, human rhinovirus (HRV), adenovirus (ADV),

 

Online supplements are not copyedited prior to posting.

©2014 American College of Chest Physicians. Reproduction of this article is prohibited without written permission from the American College of Chest Physicians. See online for more details. DOI: 10.1378/chest.13-11886

CHEST 2014; 145(1):79-86

 

Page 5: Emergence of Community-Acquired Adenovirus Type 55 as a ...both S. pneumonia and Legionella pneumophila. influenza virus (IFV) types A and B, human rhinovirus (HRV), adenovirus (ADV),

 

Online supplements are not copyedited prior to posting.

©2014 American College of Chest Physicians. Reproduction of this article is prohibited without written permission from the American College of Chest Physicians. See online for more details. DOI: 10.1378/chest.13-11886

CHEST 2014; 145(1):79-86