EHR Stakeholder workshop - EU - March 10 th & 11 th 2008 - Bruxelles 1 Dr Dirk Colaert, MD - Prof...
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Transcript of EHR Stakeholder workshop - EU - March 10 th & 11 th 2008 - Bruxelles 1 Dr Dirk Colaert, MD - Prof...
EHR Stakeholder workshop - EU - March 10 th & 11th 2008 - Bruxelles1
Dr Dirk Colaert, MD - Prof Christian Lovis, MD MPH
EHR Stakeholder workshop - EU - March 10 th & 11th 2008 - Bruxelles2
Detecting and Eliminating Bacteria
UsinG Information Technology
EHR Stakeholder workshop - EU - March 10 th & 11th 2008 - Bruxelles3
The Project in short
FP7 funded project (Framework Program 7)
This is a research initiative from the European Union
The DebugIT project proposal was ranked first
Start date: Jan 1st, 2008
End date: December 31st, 2011
11 Partners
11 Work packages
Total EU funding of the project 7M€
EHR Stakeholder workshop - EU - March 10 th & 11th 2008 - Bruxelles4
The Partners
1 Agfa Agfa HealthCare N.V.
2 HUG Les Hôpitaux universitaires de Genève
3 UNIGE Université De Genève
4 LIU LINKÖPINGS UNIVERSITET
5 EMP Empirica
6 UCL University College London
7 INSERM Institut National de la Santé et de la Recherche Médicale
8 UKLFR Universitätsklinikum Freiburg
9 TEILAM TECHNOLOGIKO EKPEDEFTIKO IDRIMA LAMIAS
10 IZIP IZIP A.S.
11 GAMA Gama/Sofia Ltd.
EHR Stakeholder workshop - EU - March 10 th & 11th 2008 - Bruxelles5
clinical context
Antibiotic resistance is a consequence of evolution via natural selection
antibiotic action is an environmental pressure
• patterns of antibiotic usage greatly affect the number of resistant organisms which develop.
• overuse of broad-spectrum antibiotics• incorrect diagnosis• unnecessary prescriptions• improper use of antibiotics• use of antibiotics as livestock food additives for growth promotion• counterfeited drugs
EHR Stakeholder workshop - EU - March 10 th & 11th 2008 - Bruxelles6
clinical context
WHO Weekly Epidemiological Record, Vol 71, No 18, 1996
antibiotic resistance in Salmonella typhimurium DT104, England and Wales, 1984-1995
EHR Stakeholder workshop - EU - March 10 th & 11th 2008 - Bruxelles7
clinical context
EHR Stakeholder workshop - EU - March 10 th & 11th 2008 - Bruxelles8
clinical context
http://www.rivm.nl/earss
EHR Stakeholder workshop - EU - March 10 th & 11th 2008 - Bruxelles9
…
a race against evolution can only be lost
new solutions must be found
This has become a new war !
New Antibiotics can not keep
up with the bacterial resistance
If this is a war: we need a new weapon
ITbiotics to help the Antibiotics
EHR Stakeholder workshop - EU - March 10 th & 11th 2008 - Bruxelles10
The DebugIT project
Clinical Care Medical research
Activities
Repositories
ClinicalData
Repository(aggregated,distributed)
Analysis
KnowledgeRepositories
(aggregated,distributed)
Reasoningengine
Knowledge
ClinicalActivity
clinical dataclinical data
Knowledge
1-CollectData
2-Learn
3-StoreKnowledge
4-Apply
EHR Stakeholder workshop - EU - March 10 th & 11th 2008 - Bruxelles11
Clinical Care Medical research
Activities
Repositories
ClinicalData
Repository(aggregated,distributed)
Analysis
KnowledgeRepositories
(aggregated,distributed)
Reasoningengine
Knowledge
ClinicalActivity
clinical dataclinical data
Knowledge
1-CollectData
2-Learn
3-StoreKnowledge
4-Apply
The Translational Framework
EHR Stakeholder workshop - EU - March 10 th & 11th 2008 - Bruxelles12
Focus points, challenges
• Technological– Interoperability– Clinical Data Repository Formalism– Federated Data Mining
• Collect everything and mine afterwards or mine on distributed data ?
– Multimodal Data Mining• Structured, unstructured, images, …
– Data Mining steered by knowledge/reasoning– Federated Knowledge Repository
• Multi format, multi source
– Reasoning• Statistical + logical• Performance• Formalism and decidability
EHR Stakeholder workshop - EU - March 10 th & 11th 2008 - Bruxelles13
Focus points, challenges
• Functional– Representation of Knowledge– Integration in Clinical Systems– Usability– Proof of concept and example of translational medicine
• Clinical Care– Decision support– Patient safety + Efficiency
• Medical Research– Pharmaco-vigilance– Strict clinical trials versus ‘real data’ mining
• a “nice picture of a dirty world”• applicability and usefulness of results• the “context” problem
EHR Stakeholder workshop - EU - March 10 th & 11th 2008 - Bruxelles14
Conclusion
• DebugIT will make a proof of concept of a generic translational framework focused on a specific clinical problem
• By it’s very nature the system will be scalable and fractal, such that it can be used from very low local levels to high strategic global levels
EHR Stakeholder workshop - EU - March 10 th & 11th 2008 - Bruxelles15
…