Echocardiographic Evaluation of Prosthetic Valves · Basic Principles By their design, almost all...
Transcript of Echocardiographic Evaluation of Prosthetic Valves · Basic Principles By their design, almost all...
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Prosthetic Valves Dr. Myla Gloria Salazar - Supe
Echocardiographic Evaluation of
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The 1st valve replacement in 1960
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There is no perfect valve
“they have introduced other, new problems into clinical medicine, so that in effect, the patient is exchanging one disease process for another”
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Basic Principles
By their design, almost all replacement valves are obstructive compared with normal native valves
Most mechanical valves and many biologic valves are associated with trivial or mild transprosthetic regurgitation(physiologic regurgitation)
Because of shielding and artifacts, insonation of the valve esp regurgitant jets may be difficult and requires multiple angulations of the probe and the use of off-axis view
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Normal Values for Implanted Aortic Valves
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Normal Values for Implanted Mitral Valves
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Basic Principles
By their design, almost all replacement valves are obstructive compared with normal native valves
Most mechanical valves and many biologic valves are associated with trivial or mild transprosthetic regurgitation(physiologic regurgitation)
Because of shielding and artifacts, insonation of the valve esp regurgitant jets may be difficult and requires multiple angulations of the probe and the use of off-axis view
![Page 8: Echocardiographic Evaluation of Prosthetic Valves · Basic Principles By their design, almost all replacement valves are obstructive compared with normal native valves Most mechanical](https://reader030.fdocuments.in/reader030/viewer/2022041213/5e02f294d9e2ea2f20410984/html5/thumbnails/8.jpg)
Physiologic Regurgitation
Washing jets to prevent thrombus formation
10-15%
Jets low in momentum homogeneous in color, aliasing mostly confined
to the base of the jet.
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Basic Principles
By their design, almost all replacement valves are obstructive compared with normal native valves
Most mechanical valves and many biologic valves are associated with trivial or mild transprosthetic regurgitation(physiologic regurgitation)
Because of shielding and artifacts, insonation of the valve esp. regurgitant jets may be difficult and requires multiple angulations of the probe and the use of off-axis view
![Page 10: Echocardiographic Evaluation of Prosthetic Valves · Basic Principles By their design, almost all replacement valves are obstructive compared with normal native valves Most mechanical](https://reader030.fdocuments.in/reader030/viewer/2022041213/5e02f294d9e2ea2f20410984/html5/thumbnails/10.jpg)
Shadowing
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Types of Prosthetic Valves
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Valve Size is not equal to EOA
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Doppler Echocardiography
Pressure Gradient Simplified Bernoulli equation: 4V2
Effective Orifice Area Continuity equation: EOA = stroke volume / VTI PrV
Better index of valve function than gradient alone
Dimensionless Index (DVI) = ratio of velocity proximal to the valve, to the velocity through the valve
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Doppler Echocardiography
Pressure Gradient Simplified Bernoulli equation: 4V2
Effective Orifice Area Continuity equation: EOA = stroke volume / VTI PrV
Better index of valve function than gradient alone
Dimensionless Index (DVI) = ratio of velocity proximal to the valve, to the velocity through the valve
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Effective Orifice Area
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Pressure Half Time
not appropriate to use the pressure half-time formula (220/pressure half-time) to estimate orifice area in prosthetic valves.
valid only for moderate or severe stenoses (< 1.5 cm2).
For larger valve areas, PHT reflects atrial and LV compliance characteristics and loading conditions and has no relation to valve area.
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Mitral Valve Continuity Equation
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Doppler Echocardiography
Pressure Gradient Simplified Bernoulli equation: 4V2
Effective Orifice Area Continuity equation: EOA = stroke volume / VTI PrV
Better index of valve function than gradient alone
Dimensionless Index (DVI) = ratio of velocity proximal to the valve, to the velocity through the valve
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Dimensionless Valve Index (DVI)
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Early and Late Complications of Prosthetic Valves
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Normal Mechanical Prosthesis at Aortic Position
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Normal Bi-leaflet Mechanical Aortic Valve (TEE)
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Stented Bioprosthetic Mitral Valve
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Prosthetic Valve Obstruction
Mechanical Valves: Thrombus or Pannus
Bioprosthetic: structural valve degeneration (SVD)
(Abnormal leaflet morphology / mobility) Increased gradient for valve subtype and size Decreased EOA and DVI Significant deviation from baseline study
#Importance of “finger printing” iEOA and DVI typically unchanged compared to baseline
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Prosthetic Valve Obstruction: Thrombus
Systole: both leaflets doesn’t close fully
Diastole: left disc opens fully, right disc immobilized
High velocity flow through single orifice
Elevated transmitralgradient = 11.2 mmHg
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Abnormal Mechanical Valve at Mitral Position
Decreased occludermotion and thrombus at the LV side of the prosthesis
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Pre- & post-thrombolysis of SJM mitral valve
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Pannus Formation in Mechanical Valve
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Pannus Ingrowth Mitral Bioprosthesis
systole diastole
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Pannus Bioprosthetic Valve
Elevated gradients across a bioprostheticmitral valve
Pannus by TEE (echogenic area on the atrial side of the prosthesis)
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Pannus formation
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Evaluation of Prosthetic Valves by Location
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Doppler parameters of prosthetic AV stenosis
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Inday – 41 year old female
Ht 149 cm Wt 53 kg BSA 1.46 m2
Concentric LVH LVMI = 119 gm/2, RWT = 0.53, LVEF 74%
Aortic root = 2.8 cmLVOT dia = 2.1 cmLVOT VTI = 26.7 Ao VTI = 98.1DVI = 0.27EOA = 0.94 cm2 iEOA = 0.64MVG = 42 mmHgPIG = 89 mmgSPAP = 33 mmHg
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Prosthesis Patient Mismatch
No detectable structural abnormality of the PV leaflets / occluders
Normal EOA and DVI for subtype
iEOA < 0.85 (0.64)
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Consequences of PPM
Worse hemodynamics
Less regression of LVH (and pulmonary HPN)
Worse functional class, exercise capacity, and quality of life
More cardiac events
Lower survival
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Indexed EOA is the only parameter shown to have any correlation with post-operative gradients &/or outcomesin prosthetic valve mismatch
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Determinants of Mismatch
larger BSA - higher cardiac output requirements
older age
smaller prosthesis size (< size19)
valvular stenosis as the predominant lesion before the operation
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Prevention of PPM
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BSA x 0.851.64 x 0.85 =
1.394
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Evaluation of Prosthetic Valve by Location
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Doppler Evaluation of Mitral Stenosis
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Doppler Evaluation of Mitral Prosthesis
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Degenerated Mitral Bioprosthesis
diastole
PISA shell
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Physiologic vs Pathologic Regurgitation
Washing jets to prevent thrombus formation
10-15%
Jets low in momentum homogeneous in color, aliasing mostly confined
to the base of the jet.
Central
Paravalvular
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Severe Paravalvular MR in TEE vs TTE
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Mild central MR across a bioprosthetic
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Large paravalvular leak
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Dehiscence
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Paravalvular Leak
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Periprosthetic Leak (CoreValve)
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Significant Mechanical Mitral Regurgitation
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Severity of Prosthetic Aortic Valve Regurgitation
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Severity of Mitral Regurgitation
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