ECG and cardiac resynchronization Case report of … · ECG and cardiac resynchronization Case...

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ECG and cardiac resynchronization Case report of a non responder Pierre Bordachar, MD CHU de Bordeaux Hôpital Haut Lévêque

Transcript of ECG and cardiac resynchronization Case report of … · ECG and cardiac resynchronization Case...

Page 1: ECG and cardiac resynchronization Case report of … · ECG and cardiac resynchronization Case report of a non responder Pierre Bordachar, MD CHU de Bordeaux Hôpital Haut Lévêque

ECG and cardiac resynchronization

Case report of a non responder

Pierre Bordachar, MDCHU de Bordeaux

Hôpital Haut Lévêque

Page 2: ECG and cardiac resynchronization Case report of … · ECG and cardiac resynchronization Case report of a non responder Pierre Bordachar, MD CHU de Bordeaux Hôpital Haut Lévêque

• Man 57 years old• Ischemic cardiomyopathy• Ejection fraction 20%• NYHA class III• Optimal medical therapy• QRS 145 ms

DI

DII

DIIIaVRaVL

aVF

V1

V2• QRS 145 ms• Aspect of left bundle branch

block

Class I recommandation for DAI-CRT

V2

V3

V4

V5

V6

Page 3: ECG and cardiac resynchronization Case report of … · ECG and cardiac resynchronization Case report of a non responder Pierre Bordachar, MD CHU de Bordeaux Hôpital Haut Lévêque

DI

DII

DIIIaVRaVL

aVF

V1

Implantation

V1

V2

V3

V4

V5

V6

Aspect of biventricular pacingRight ventricular lead: apexLeft ventricular lead: lateral wall

Page 4: ECG and cardiac resynchronization Case report of … · ECG and cardiac resynchronization Case report of a non responder Pierre Bordachar, MD CHU de Bordeaux Hôpital Haut Lévêque

• After one month: hospitalization for severe heart fa ilure • 100% ventricular pacing

DI

DII

DIIIaVRaVL

aVFaVF

V1

V2

V3

V4

V5

V6

Aspect of apical right ventricular pacing

Dislodgement of the left ventricular lead

Page 5: ECG and cardiac resynchronization Case report of … · ECG and cardiac resynchronization Case report of a non responder Pierre Bordachar, MD CHU de Bordeaux Hôpital Haut Lévêque

Repositionning of the left ventricular lead

Optimization of AV delays- sensed P AV delay: 140 ms- paced P AV delay: 180 ms

Page 6: ECG and cardiac resynchronization Case report of … · ECG and cardiac resynchronization Case report of a non responder Pierre Bordachar, MD CHU de Bordeaux Hôpital Haut Lévêque

DI

DII

DIII

aVR

aVL

LBBB LV RV BIV

ECG for different pacing configurations

aVF

V1

V2

V3

V4

V5

V6

Page 7: ECG and cardiac resynchronization Case report of … · ECG and cardiac resynchronization Case report of a non responder Pierre Bordachar, MD CHU de Bordeaux Hôpital Haut Lévêque

• After 6 months, clinical non-response: NYHA class I II• 100% ventricular pacing

DI

DII

DIII

aVR

aVL Fusion between intrinsic and pacedaVF

V1

V2

V3

V4

V5

V6

activations

Page 8: ECG and cardiac resynchronization Case report of … · ECG and cardiac resynchronization Case report of a non responder Pierre Bordachar, MD CHU de Bordeaux Hôpital Haut Lévêque

DI

DII

DIII

aVR

aVL

AV 200

AV160

AV140

AV120

AV100

AV70

• In patients without AV blockMajor impact of the AV delay on the ventricular activation sequence

Electrocardiographic aspect during optimization of the AV delay

aVL

aVF

V1

V2

V3

V4

V5

V6

Programming of a shorter AV delay

Page 9: ECG and cardiac resynchronization Case report of … · ECG and cardiac resynchronization Case report of a non responder Pierre Bordachar, MD CHU de Bordeaux Hôpital Haut Lévêque

LV LV60

LV40

LV20

BV RV20

RV40

RV60

RV

DI

DII

DIII

aVR

aVL

Electrocardiographic aspect during optimization of the VV delay

aVL

aVF

V1

V2

V3

V4

V5

V6

Page 10: ECG and cardiac resynchronization Case report of … · ECG and cardiac resynchronization Case report of a non responder Pierre Bordachar, MD CHU de Bordeaux Hôpital Haut Lévêque

DI

DII

DIII

aVR

• After 3 months: poor clinical improvement• 81% ventricular pacing

Atrial undersensingaVR

aVL

aVFAtrial sensing

reprogramming

Page 11: ECG and cardiac resynchronization Case report of … · ECG and cardiac resynchronization Case report of a non responder Pierre Bordachar, MD CHU de Bordeaux Hôpital Haut Lévêque

Take away messages

• ECG is mandatory during follow-up of patients with cardiac resynchronization

• ECG recording in the different pacing configuration s is mandatory to diagnose loss of capture at follow-up

• ECG should be controlled before echocardiographic o ptimization of AV delays

• VV delay programming impacts the ECG pattern but is difficult

• Correct functioning of the atrial lead is mandatory during biventricular pacing

Page 12: ECG and cardiac resynchronization Case report of … · ECG and cardiac resynchronization Case report of a non responder Pierre Bordachar, MD CHU de Bordeaux Hôpital Haut Lévêque

In ICD patients, analysis of systematic remotely tr ansmitted EGMs is as important as interpretation of tachycardia episodes

Jacques Clémenty, MDUniversity Hospital of

Bordeaux

Page 13: ECG and cardiac resynchronization Case report of … · ECG and cardiac resynchronization Case report of a non responder Pierre Bordachar, MD CHU de Bordeaux Hôpital Haut Lévêque

Systematic transmitted ECG: R wave double counting, but no therapy delivered

Page 14: ECG and cardiac resynchronization Case report of … · ECG and cardiac resynchronization Case report of a non responder Pierre Bordachar, MD CHU de Bordeaux Hôpital Haut Lévêque

Large QRS complex: 200 ms

Page 15: ECG and cardiac resynchronization Case report of … · ECG and cardiac resynchronization Case report of a non responder Pierre Bordachar, MD CHU de Bordeaux Hôpital Haut Lévêque

Real-time telemetry at follow-up extra-visit

R wave double counting

FF

Surface ECG

Markers

RV

A

FF

Page 16: ECG and cardiac resynchronization Case report of … · ECG and cardiac resynchronization Case report of a non responder Pierre Bordachar, MD CHU de Bordeaux Hôpital Haut Lévêque

Change in the detection modality

Only the positive part

of the ventricular EGM

will be sensed

Page 17: ECG and cardiac resynchronization Case report of … · ECG and cardiac resynchronization Case report of a non responder Pierre Bordachar, MD CHU de Bordeaux Hôpital Haut Lévêque

After Reprogramming. Real-time telemetry

No R wave double counting

Surface ECG

Markers

RV

A

FF