Dusjagr nano filia_size

download Dusjagr nano filia_size

of 25

  • date post

    16-Apr-2017
  • Category

    Education

  • view

    489
  • download

    1

Embed Size (px)

Transcript of Dusjagr nano filia_size

NanoHacking: Converging Life and Tech at the NanoscaleSEEING THINGS But how big/small is it?Dr. Marc R. Dusseiller aka dusjagr www.dusseiller.ch/labsBiofilia & LUMA Centre at Aalto University, Helsinki

The Size of Things

Small seems to be the state of the art

Why are we so big?

Why must our bodies be so large compared with the atom?

Erwin Schrdinger, "What Is Life? The Physical Aspect of the Living Cell ", 1944 Austrian/Irish physicist and Nobel Laureate (1887 - 1961)

The Size of Things

Lngenskalen in der Biologie

Atome, Kristalle und kleine Molekle

Computermodels

Molekle

Lipid MolekleWichtiger Bestandteil der Zellmembran

Computermodels

DNA

1 Umdrehung = 10 Basenpaare = 3.4 nmBreite = 2 nm

Trgerin der Erbinformation

4 Nukleotiden

GATC

Doppelhelix

DNA

Was wre die theoretische Lnge des menschlichen Genoms?Schtzungen...

DNA

Was wre die theoretische Lnge des menschlichen Genoms?27'000 oder 150'000 Gene, weiss man doch nicht so genau...

75% non-coding regions with unknown function

3'200'000'000 Basenpaare

Diploides Genom auf 23 Chromosomen

Frauen haben offenbar eine lngere DNA :-)

0,34 nm/bp * 6,4 Mrd bp = 2,18 Mrd nm = 2,18 m

DNA als Nano-LEGO Baukasten

Computermodels

Steifes Polymer

Negative Ladung

Self-Assembly

Proteine

Entstehen durch Translation von mRNA

Computermodels

Protein Komplexe

Zb RibosomBesteht aus Proteinen und Ribonukleinsuren

Durchmesser 25 nm

Computermodels

Viren

Computermodels

Bakterien

Computermodels

Zellen

Computermodels

Extrazellulre Matrix

Plastisches und bewegtes Gefge

Zellen im Verbund

Computermodels

Einzellige Organismen

Computermodels

Pantoffeltierchen, Paramecium (Ciliate)

Amoebae

Computermodels

Multicellular Microorganisms

Caenorhabditis elegans, Fadenwurm

Tardigrada, Brtierchen, war 2007 im Weltraum, ESA Projekt TARDIS

Computermodels

Rotifers (1000 Cells)

Seeing Things

Looking at Things

Seeing with light aka your eyes

Seeing with light aka your eyes

Zivalice Laser Projector

A small drop of pond water acts as a lens, shine a laser through it and see!

Click to edit the title text format

Click to edit the outline text formatSecond Outline LevelThird Outline LevelFourth Outline LevelFifth Outline LevelSixth Outline LevelSeventh Outline LevelEighth Outline LevelNinth Outline Level

Slide