Dry Powder Granulation Equp
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Transcript of Dry Powder Granulation Equp
7/25/2019 Dry Powder Granulation Equp
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DRY POWDER & GRANULATION
EQUIPMENTS
STARCH PASTE KETTLE CONTA BLENDERTURBOSIFTER CUM MULTIMILLwith Lifter & Tipper Unit (LTU)
FLUIDAIR Fluid Bed Dryer RAPIDMIX High Shear Mixer Granulator
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MIX MIX PI
HIGH SHEAR MIXER GRANULATOR
The Starch Paste kettle is a specially designed unit for preparation of binder material. It is a
hemispherical kettle with jacket mounted on trunion supports with the help of shaft. The kettle has a
small cylindrical top shell with a spout for pouring out binder mass.
Jacket is provided with steam accessories i.e.
pressure guage, safety valve and vent cock. The Kettle is also provided with a lever with hand wheel to
accomplish tilting manually. The kettle is provided with 16 swg thick SS 304 loose lid.
SALIENT FEATURES
All contact parts are made of
Bottom discharge with flush bottom ball valve.
Mechanical tilting with worm / wormwheel arrangement. Motorised drive mechanism for tilting as
an optional.
The kettle is provided with Anchor
type beater for paste mixing with dual speed option.
SS 316.
Detachable Agitator with Anchor blades and Teflon scrappers.
Paste Kettle with Hydraulic Lifting and Lowering Arrangement - Optional.
RAPIDMIX -- High Shear Mixer Granulator is a versatile
machine developed for mixing as well a s granulation of
ingredients. The multi-bladed dual speed impeller is fitted close
to the base of the mixing bowl whereas the chopper is mounted
on the wall of the mixing bowl. Both the impeller as well as the
chopper have dual-speed options for gently distributing the
granulating solution as it is added and for fluidizing the charge
and creating the vortex of the material being mixed by both
vertical and horizontal components.
SALIENT FEATURES
Capacity ranging from 10 ltrs. to 1000 ltrs. ( i.e. from 5 kgs.
to 400 kgs. Approx. ).
Design and finish comply with GMP standards.
Integration of dry blending and wet granulation processes into
one-step mixing and granulation.
Telescopic lifting arrangement for main impeller as an option.
CIP Manifold washes all product contact surfaces.
Controlled and enclosed mixing complying to GMP
standards.
Specially designed impeller blades to optimise the high speed
agitation of the charge.
Precision engineering to minimize clearance between bowl
and impeller.
The machine is supplied with standard manual controls.
Optionally, ca n also be supplied with Programmable Logic
Control [PLC] system and MMI for the visual display of the
operating parameters.
Dual-speed option for the Impeller as well as Chopper to
ensure outstanding results for different types of products.
Specially designed air-purged GMP shaft seals keep powder
away from mechanical drives a nd prevent product
contamination.
Built-in piping and drainage system for thorough cleaning and
flushing of water through both drive shaft seals without the
need to remove these seals.
Jacketed Bowl Provision -- Optional.
Flame proof construction -- Optional.
In situ product transfer with IPC by IPC Lifter and
Positioner for dust free operation and better GMP
compliance - Optional.
MACHINE LAYOUT
Various options are provided in the machine layout to suit
the individual customer’s applications. Orientation of the
following items can be made to suit specialised
applications :
Positioning of discharge port.
Height of the discharge port from the floor.
Platform height.
Access steps and railing.
Utility connections.
Top dish opening mechanism.
Position and size of the charging port for powders and
liquids through the bowl’s top dish.
Details of the room layout required for installation of
the machine.
D r y P o w d
e r &
G r a n u l a t i o
n L i n e
STARCH PASTE KETTLE
The Turbosifter cum Multimill machine is used for high speed sieving and milling s imultaneously to achieve
uniform properties. Sieving and milling process is achieved by means of passing the dry granules through
Sifter and then passing through the Multimill. The time taken for the entire operation is less as compared to
vibratory Sifter and Multimill individually. The process is less dusty and laborious.
Loader and Tipper Unit lifts Fluid Bed Drier b owl, tilts and charges dry powder / granules to the
hopper of Turbosifter cum Multimill. Dust free operation between LPU and Turbosifter cum Multimill is
ensured by interconnecting flexible Latex bellow.
SALIENT FEATURES
High speed sieving with quick changeover of sieves.
Dust free discharge and charging.
Choice of material of construction (SS 304, SS 316, SS 316L) product contact parts.
Flame-proof construction – optional.
'LTU' is a simple stand alone unit allowing minimum
manpower and better GMP concept. It is ideal for linear flow and allows faster operation with
minimum dust generation and reduced changeovers.
Tilting Head is integral with the lifting head and housed on the yoke with horse shoe shaped Stainless
Steel lifting cradle.
The tilting degree of the cone is provided by double action hydraulic cylinder through specially
designed rack and pinion assembly.
Hydraulic Power pack is operated through a custom built panel with pushbutton station for Raising /
Lowering & Tilting, with limit switches for controlling the UP / DOWN traverse.
TURBOSIFTER CUM MULTIMILL WITHLIFTER AND TIPPER UNIT (LTU)
The Conta Blender is latest addition to the range of blenders which conforms to GMP
concepts. It gives uniform mixing / lubrication of powder / granules and better mixingefficiency as compared to conventional Blenders like Double Cone Blender, V ShapeBlender, Octagonal Blender, Polygonal Blender, etc.
It lays emphasis on dust free transfer of powders / granules at different stages from sizing /dispensing to compression / filling of tablets, capsules or dry powder.
The system consists of a mobile bunker, which is clamped to a rotating arm having liftingarrangement. The bunker is loaded with sized granules to be mixed and is clamped to therotating arm and locked. The material is tumbled in the partial void inside the bin for a pre-determined period. The Conta Blender rotates in a diagonal and eccentric plane, shufflingthe product intimately and resulting in homogenous blend within 5-20 minutes approx.Conta blender has flexibility of batch volume wherein varying size of containers can bemounted on a drive console, which is equipped with clamping arms.
0Design of arm is such that the shell is given a tilt of 15 , thereby giving uniform mixing / lubrication of powder / granules. The Conta Blenderis provided with mechanical stopper to the bunker trolley, to ease in locating and unloading the bunker after completion of mixing operation.The drive consists of a brake motor with helical gear box, which is coupled to the rotating arm shaft by gear coupling.
SALIENT FEATURES
Capacity : 25 Kgs to 500 Kgs.
Fluid coupling between motors and gear box to take care of initialtorque.
An ideal blender for dry blending of powder and lubrication ofgranules / powder.
Tumbling principle of powder in a partial void enableshomogenous mixing of active ingredients, additives and rawcarrier materials.
It enables dust free operation in processing area.
Electric or Manual inching arrangement to bring the arm withbunker back to rest at initial position.
Control panel is equipped with Programmable Logic Control(PLC) system and MMI for the visual display of the operatingparameters.
Variable frequency drive / AC Inverter for the variable batch speed
control
CONTA BLENDER
Lifting andPositioning
Unit for
Bunker /IPC Lifter and
Tipper Unit
TECHNICAL SPECIFICATIONS
CHOPPER ASSLY
COUNTERWEIGHT
L
DISCHARGE
PORT W B
STAIRCASE
PLAN
ELEVATION
F D
H
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FLUIDAIRE Fluid Bed Dryer works on the principle of creating a fluid turbulence in agranulated or powdery wet product by means of hot air (or dehumidified air) flowing in an
upward direction and drying the product to the required degree.
FLUID BED DRYERS
SALIENT FEATURES
Short drying time and Low dryingtemperature
Uniform drying
Rapid exchange of granules
Single piece retarding chamber and finger bag
chamber with inflatable gasket.
Pneumatic lifting & locking for product
container with retarding chamber.
Heating by electricity / steam air heating
systems with SS heat exchangers.
Fully automatic bag shaking arrangement.
Intrinsically safe earthing mechanism -
Optional.
AHU with Inlet-air filtration system with 20
Micron Coarse Filter, 5 Micron Pre Filter and
0.3 micron HEPA filters ( -99.9 % ) as an
option. Compact design. Contact parts in Stainless Steel 304 quality
or 316 quality or 316L quality as per user's
requirement. Differential pressure guage across micro-vee
and filter bag as an optional.
Þ
ADVANTAGES
In the Fluidaire Fluid Bed Dryer, the loaded wet material is
completely fluidised by a powerful stream of hot air, thereby
achieving high heat transfer rate and uniform temperature
distribution across the product. This results in reducing drying
time considerably and achieving high productivity in
comparison with other dryers. As the drying temperature is low
and duration is short, physical and chemical properties of the
product are generally not affected, thereby facilitating the use
of the dryer for heat sensitive products. Common problems
faced during drying such as lump formation, case hardening
etc. are minimised due to total fluidisation.
It is not recommended to dry liquids or pasty materials in the
Fluidaire Fluid Bed Dryer.
WORKING PRINCIPLES Atmospheric Air is drawn by means of a Blower and is passed
through a fine dust HDPE filter thereby freeing the air from
impurities. The pure air is subsequently heated by steam or an
electric heater. The temperature is controlled by means of apreset themostat or by a temperature regulator. Heaters are
electrically operated with thermostat controls and are made in
stainless steel 304. Electrical interlocking of heater and blower
is provided. Steam radiators can also be provided instead of
electrical heaters.
Steam radiators are suitable for operation at 3.5 kg. / sq. cm.
pressure having finned tube is provided in S S casing. A
suitable steam control manifold is provided with all S S or all
copper or combination of copper and S S or S S andaluminium construction depending upon the customer's
requirements.
The clean hot air stream flowing upwards, fluidises the batch offlowable moist material charged in the bowl. The product bowl
is equipped with a stainless steel mesh to facilitate air flow
through the material. A homogeneous distribution of
temperature is achieved as the hot air comes into contact with
the entire surface of individual particles during fluidisation,
resulting in rapid and effective drying of even the smallest
traces of residual moisture.
A Bag filter provided in the filter chamber arrests the
particulates in the air flow. The particulates fall back into the
bowl when the bag shaker is set into operation at the end of
the working process. The air containing the moisture escapes
through the exhaust.
An outlet air damper and inlet air damper regulates the
quantity of air.
The fluidising air for drying is drawn by the Blower located on thetop section of the Fluid Bed Dryer. (The Blower can also be
positioned elsewhere away from the Fluid Bed Dryer)
IMPORTANT
In case the product contains solvents or inflammable
substances, it is essential that the Dryer is steam operated
and provided with a flame-proof motor.
Air Handling Unit consists of Inlet Air Filters
Three stage-filtering device for incoming air is provided. The filters
are mounted in a stainless steel housing. The details of the filters are
as follows:
- Primary filter 95% efficiency up to 20 microns.
- Intermediate filter ( EU 7 ) 95% efficiency up to 5 microns.- Final filter HEPA filters (EU 8) 99.9% efficiency up to 0.3
microns - Optional.
Retarding Chamber And Finger Bag Assembly:
This is a cylindrical shell with a dished end at the top, made out of
S S 304 or S S 316. The air outlet nozzle is provided on top for
connecting to exhaust air fan via suitable length of ducts. This
chamber houses the filter bag assembly provided with top ring
bracket for holding the finger bag and sealing ring with inflatable
tube gasket at the bottom. The retarding chamber is provided with
sight glass and a lamp.
Bag Shaking and Lowering Device:
This is a pneumatically operated specially designed three stage bag
Shaking arrangement. Proper design selection of stroke length and
predetermined shaking time helps, up & down movement of the
cylinder, giving jerks to the bag for dedusting.Gaskets :
Following gaskets are provided on the machine
- Bottom chamber and product container.
- Product container and retarding chamber.
- Inflatable tube gasket between sealing ring of finger bags and
retarding chamber wall.
Exhaust Air Blower:
Blower consists of centrifugal fan with backward curved impeller in
stainless steel / Aluminium/ MS painted . The impeller is mounted
directly on motor shaft.
Blower can also be supplied with Flame-proof construction
as an optional.
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FLUID BED DRYERS
Explosion Vent with Rupture Disc:
Proper vent connection from retarding chamber is provided to
carry the inflammable solvent vapors along with hot air directlyto the atmosphere in case of any explosion or any excess
pressure built up. A rupture disc of appropriate material andthickness is provided in the explosion vent.
Sampling Device:
A suitable sampling device is provided in the product container
to carry out periodical sampling & analysis of material being
dried as an optional.
Dampers:
A butterfly damper is provided in the inlet and outlet air duct. A
lockable lever is provided for manual operation of the damper.
Damper can alternatively be provided with a Rotary motorisedactuator with indication of % opening in MMI panel as an
option.
Damper closes automatically when the bag shaking cycle starts
and opens once the shaking cycle is over.Earth Safety Relay:
During fluidization static charge may develop due to productcharacteristic and heavy turbulent condition inside the retarding
chamber. A safety earth circuit relay is provided to discharge
static charge developed during fluidisation.
Clean In Place (CIP) System can be provided as an Option.
PRODUCT CONTAINER (BOWL) SEALING
The product bowl is hermetically sealed with the retarding
chamber. The sealing is done by means of a hand operatedlever or through a pneumatically operated bowl lifting &
sealing arrangement with inflatable gasket which ensuresproper sealing of the bowl to the retarding chamber. Ensure
that the lifting platform is in the same plane for proper sealing
of the bowl with the retarding chamber.
AIR DUCTS (USER'S SCOPE)
Suitable ducts must be provided for the air inlet and outlet
from outside the external wall, close to which the dryer is
installed.
It is recommended to draw the air from outside the room
where the dryer is installed.
Avoid all unnecessary resistances (like narrow bends etc.)
A suitable rain protection cowl with bird mesh is to be
provided at the end of each duct to prevent rain, dust etc.
from entering the duct.
The ducts can be fabricated from Mild Steel or Stainless
Steel material.
Fluid Bed Dryers are also supplied with solid flow monitor as
an optional feature for detecting product leakage from filter
bag and to trip the blower motor.
TECHNICAL SPECIFICATIONS
Model FBD 30 FBD 60 FBD 120 FBD 150 FBD 200 FBD 250 FBD 300
Gross Capacity - Ltrs. 100 195 425 475 625 725 1000
Working Capacity - Ltrs. 60 115 255 285 375 435 600
Capacity of Dryer in Kg. 30 60 120 150 200 250 300
Blower Motor - HP - Std. 5.0 10 15 15 20 20 30Blower Motor - HP in case
of 20, 5 & 0.3 micron Air Filter 7.5 15 20 20 25 30 40
Steam Consumption at2
3 - 4 Kg/cm Pressure 75 - 85 150 - 160 200 - 215 225 - 240 250 - 265 275 - 300 300 - 325
Electrical Heater Capacity -KW 18 36 42 48 N.A. N.A. N.A.
Dimensions All Dimensions are in mm
L 750 1425 1950 2075 2150 2225 2500
W 950 1300 1585 1650 1700 1750 2000
H 2225 2775 3400 3550 3625 3750 4150
BH 775 885 1075 1115 1150 1250 1375
L1 450 525 725 750 800 800 1000
1618
17 21
19
10
2
4
23
22
11 12
13
20
B H
H
1
3
5
7
8
6
9
14
24
15
CONTROL PANEL
EXHAUST
DUCTING
2" BSP DOP
TEST NOZZLE
R O O M
H E I G H T
OPERATING
PANEL
ELEVATION
W
SIDE VIEW
L L1
HOT AIR
INLET DUCTING
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Anchor Mark Pvt. Ltd. offers comprehensive technical consultancy and advisory assistance to all genuinely interested parties. Personnel training and follow-upservice is promptly provided as sales back-up.
As the design and manufacture of ANCHOR MARK PVT. LTD. machines are subject to improvement, the product supplied may differ in some details from the specificationsand illustrations given.
101 A, Kandivli Co-op. Industrial Estate Ltd., Charkop, Kandivli (W), Mumbai - 400 067. INDIA.
Tel. : 91-22-28682001 Fax : 91-22-28682250E-mail : [email protected] Website : www.anchormark.com
The Octagonal Blender is useful for
mixing dry powder and dry
granules due to its octagonalshape. The mixer is rotated at a
slow speed and has a removable
baffle mounted through
rectangular openable lid. It
occupies less space as compared to
other blenders like V and Cone
blenders.
The Double Cone Blender is an efficient
and versatile machine for mixing Dry
Powder and Granuals homogeneously.Two-thirds of the volume of the Cone
Blender is filled to ensure proper mixing. It
can be used for phamaceutical, food,
chemical and cosmetic units.
SALIENT FEATURES
The conical shape at both ends enables
uniform mixing and easy discharge.
The Coating pan is used for coating of tablets and
confectioneries. The pan of the machine is
mounted in a inclined position facilitating effective
coating of tablets. This machine is widely used in
pharmaceuticals, confectioneries etc.
SALIENT FEATURES
The drives system is provided with a variable
speed pulley for changing the RPM for different
types of coating.
The machine is equipped with a hot bowler for
feeding hot air in the regular temperature range0 0
of 40 C to 80 C. Thermostat makes selectionof required temperature easy.
SALIENT FEATURES
Octagonal Blender is supplied with a bin charging system or can be
designed for vacuum charging.
It is a very useful machine for pharmaceutical industry wherein gentle
blending of dry granules or powder is to be done. It is a slow speed
blender and has a removable baffle mounted through a rectangular
openable lid.
The bin charging system can also be incorporated in it which is a dust
free closed system for charging and discharging of powders or
granules.
The power consumption is comparatively lower than the other similartype of blenders.
Capacity : 100 ltrs - 3000 ltrs.
Flame-proof motor can be supplied as an optional.
Capacity : 20 ltrs. to 3000 ltrs.
The cone is statically balanced to avoid any excessive load on the gear
box and motor.
While the powder can be loaded into the cone through a wider
opening, it can be discharged through a Mucon valve or a slide valve.
Depending upon the product, paddle type baffles can be provided on
the shaft for better mixing.
Maximum care has been taken to ensure safe operation of the unit. It
can also be operated through a timer.
The contact parts are made of S.S. 304 or S.S. 316 quality as per
user's requirement.
Damper is provided for controlling the volume of air intake.
Flame-proof motor can be supplied as optional.
Variable frequency drive for speed variation as an optional.
Capacity : 30 kgs to 200 kgs. (450 mm to 1500 mm). Suitable for
coating of Tablets and Confectioneries.
OCTAGONAL BLENDER DOUBLE CONE BLENDER
COATING PAN
The tumbler type Drum Blender is ideal
for mixing dry powder and granular
material. The unique baffle fitted on the
lid ensures uniform mixing. This
blender is ideally used in the production
of pharmaceutical, chemical, food
products & cosmetics units.
SALIENT FEATURES
Loading of the materials into the
drum is easier as the lid is easily
removable.
Conical baffles fitted on lid ensures uniform moving and mixing.
The conical bottom portion of the drum enables easy flow while
unloading.
The outlet is provided with Mucon Valve.
Contact parts in S.S. 304 or S.S. 316 quality as per users' requirement.
Capacity : 200 ltrs. to 600 ltrs. ( 60 kgs. to 200 kgs.)
DRUM BLENDER
The Mechanical Sifter is ideal for gradation
and separation of dry powder / granules. By
utilising different sizes of screens materials can
be sifted and separated until the required size
is obtained. It works on the principle of
gyratory vibration. This machine is used in the
production of Chemicals, Pharmaceuticals,
Dyestuffs, Ceramics, Flour Products,
Cosmetics, Spices etc.
SALIENT FEATURES
All contact parts are made from S.S. AISI
304 material or 316 quality. Contact parts
can be provided as an optional.
MECHANICAL SIFTER
Screens are interchangeable depending upon the required sizes of
separation.
Portable, compact and easy to handle and dismantle for cleaning.
Flame-proof motor can be supplied as an optional.
Capacity : SFT-250 SFT-500 SFT-750
25 kg./hr. 50 kg./hr. 100 kg./hr.
The Multimill is utilized for granulating,
pulverising, shredding and chopping of
materials. This can be used for dry as well as
wet granulation. Odd-size materials / granules
can be reduced to the required size by fitting
interchangeable perforated screens around
the swing hammer blades. The machine is
widely used in the production of chemicals,pharmaceuticals, dyestuffs, ceramics,
cosmetics, spices etc.
SALIENT FEATURES
Contact parts in S.S. 304 or S.S. 316
quality as per user's requirement.
The Multimill is compact, easy to operate
and dismantle for cleaning.
Capacity : 50 to 200 kg./hr. depending on the characteristics of powder
and mesh size required.
MULTIMILL
Variable frequency drive for speed variation as an optional.
Height of discharge can be made to suit different capacity IPC height.
MACHINES CAN BE SUPPLIED FOR 380 VOLTS 3 PHASE 50 Hz OR 220 VOLTS 3 PHASE 60 Hz AS PER CUSTOMER’S REQUIREMENTS