Drugs Study Guide Student Table(1) (1)

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Pharmacology Study Guide Directions: Fill in the table, using the drug information in Lippincott Advisor for Education> Drugs. The document is being left in .docx format so you can fill in the information and utilize the document as a study guide for the material. Bring copy of study guide to class. It will be completed in class as a group project and reviewed, if time permits, by the game “20 Questions”. Selecte d Drugs Used Specifi cally for Osteopo rosis Drug Classifica tion Drugs in Class Mechanism of Action Indication s Contraindi cations Adverse Effects Interactio ns Dosages Bisphospho Alendronat -Inhibit Osteoporos -drug -headache, Prevention Rev. 4/5/2015 JAS

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Drugs study guide biphosphonate

Transcript of Drugs Study Guide Student Table(1) (1)

Pharmacology Study Guide

Directions: Fill in the table, using the drug information in Lippincott Advisor for Education> Drugs. The document is being left in .docx format so you can fill in the information and utilize the document as a study guide for the material. Bring copy of study guide to class. It will be completed in class as a group project and reviewed, if time permits, by the game “20 Questions”.

Selected Drugs Used

Specifically for

Osteoporosis

Drug Classification

Drugs in Class Mechanism of Action

Indications Contraindications

Adverse Effects Interactions Dosages

Bisphosphonates

Alendronate (Fosamax)

-Inhibit osteoclastic-mediated bone resorption indirectly enhancing bone mineral density

Osteoporosis preventionOsteoporosis treatmentIn men and postmenopausal women

-drug allergy, hypocalcemia, -esophageal dysfunction-inability to stand or sit upright for 30

-headache, GI upset, joint pain-esophageal burns-osteonecrosis of the jaw

Prevention- 5 mg/day or 35 mg/wk.Treatment 10 mg/day or 70 mg/wk.

Rev. 4/5/2015 JAS

minutesNursing Care: Take medication with a full glass of water, upon rising. Remain sitting/standing upright for 30 minutes. If hospitalized, and cannot follow these cautions hold due to long half-life, and no problem for several days.Check for severe (incapacitating) bone, muscle, and/or joint pain, low energy fractures when on med for long time.Notes: Oral, Non-estrogen, non-hormonal option. Reduces risk of hip fracture by

Rev. 4/5/2015 JAS

51%, spinal fracture by 47%, and wrist fracture by 48%.Caution in clients with dysphagia, esophagitis, esophageal ulcer, or gastric ulcer. Recommended for 5 years and reassess. Half-life 10 years d/t storage in bone. Onset : 3 weeks

Zoldronic Acid

Rev. 4/5/2015 JAS

Nursing Care:

Risedronate Sodium

Nursing Care:

Ibandronate

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Nursing Care:

Selective Estrogen Receptor Modulators (SERM’s)

Raloxifene HCL

Notes: Has positive effects on cholesterol level. Not best choice for women near menopause d/t hot flashes adverse effects.Onset: 8 weeks.

Rev. 4/5/2015 JAS

Hormone Calcitonin

Nursing Care:

Recumbant Human Parathyroid Hormone

Teriparatide

Nursing Care:

Rev. 4/5/2015 JAS

Monoclonal Antibody

Denosumab (Prolia)

Nursing Care:

Vitamin D Analogue

Calcitriol

Nursing Care:

Rev. 4/5/2015 JAS